TWAS hub - UBE2FP3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.180	0.054	0.00041	0.057	NA	0.005	NA	0.045	4.2e-04	NA	0.17000	NA	1.7e-03
2	GTEx	Brain Putamen basal ganglia	0.377	0.101	0.00054	0.216	NA	0.105	NA	0.179	7.6e-06	NA	0.00180	NA	4.9e-05
3	GTEx	Testis	0.146	0.056	0.00290	0.102	NA	0.072	NA	0.081	3.0e-05	NA	0.00043	NA	1.9e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Heart disease (siblings)	5.3	6.5	10.7	-0.6	3.3	2.9
Exposure to tobacco smoke at home	5.1	5.8	6.6	2.3	2.3	2.6
Age at last live birth	5.1	7.3	12.3	-0.5	3.1	3.5
Smoking Status	4.4	10.6	13.4	3.7	2.7	3.3
Ever smoked	4.4	7.8	12.8	3.6	1.6	2.8
Maternal smoking around birth	3.8	5.5	11.8	3.4	1.3	1.8
Past tobacco smoking	3.7	6.9	13.1	-3.6	-1.2	-2.4
Noisy workplace	3.7	4.6	12.9	3.6	0.9	-0.1
Fractured/broken bones in last 5 years	3.7	4.8	12.5	3.5	-0.6	1.3
Ever had hysterectomy (womb removed)	3.6	4.1	5.2	1.5	2.3	2.2
Qualifications: CSEs or equivalent	3.5	4.6	5.8	1.5	-2.4	-2.4
Illnesses of father: Heart disease	3.5	4.9	10.4	0.8	3.2	1.9
Back pain experienced in last month	3.5	5.1	8.9	3.0	1.7	1.8
Supplements: Vitamin C	3.4	4.0	7.7	-0.4	2.8	2.0
Other serious medical condition/disability diagnosed by doctor	3.2	4.1	6.1	1.4	2.1	2.5
Smoking status: Previous	3.2	4.8	9.5	3.1	1.1	1.9
Pain experienced in last month	3.1	5.2	12.5	-3.5	-1.2	-1.2
Mouth/teeth dental problems: Loose teeth	2.9	3.5	5.4	0.3	2.2	2.3
Type 2 Diabetes (T2D) (2012)	2.8	3.3	4.1	1.3	-2.0	-2.0
Current tobacco smoking	2.8	4.6	6.9	1.3	2.3	2.6
Number of full brothers	2.8	3.6	9.7	3.1	0.4	0.9
Supplements: Zinc	2.7	3.0	5.4	-0.8	2.3	1.7
Had menopause	2.7	3.4	4.6	-2.1	1.9	1.4
Exposure to tobacco smoke outside home	2.7	3.6	9.2	3.0	0.3	1.2
Commuting to job workplace: Cycle	2.7	3.3	5.9	-0.7	1.9	2.4
Medication for hormone replacement therapy	2.5	2.8	5.8	-0.1	-1.6	-2.4
Supplements: Calcium	2.5	2.7	4.5	-1.3	2.1	1.4
Hearing difficulty/problems: Yes	2.4	3.7	7.2	2.7	1.4	1.3
Serious illness, injury or assault to yourself	2.4	2.9	3.2	1.8	1.8	1.6
Alzheimer’s Disease (including proxy)	2.3	3.3	4.3	-2.1	1.4	1.9
Mean time to correctly identify matches	2.3	4.3	12.9	-3.6	0.2	0.3
Alzheimer’s Disease (in father)	2.2	2.4	4.2	-1.2	2.0	1.3
Average weekly fortified wine intake	2.2	2.6	5.3	0.6	2.3	1.4
Forced expiratory volume in 1-second (FEV1), predicted	2.2	4.6	8.0	0.5	-2.4	-2.8
Cholesterol lowering medication	2.2	3.2	5.7	0.1	1.9	2.4
Illness, injury, bereavement, stress in last 2 years	2.1	2.5	3.8	-1.9	-1.1	-1.6
Smoking status: Current	2.1	3.3	4.8	1.1	2.0	2.2
Had major operations	1.9	2.2	6.4	0.3	2.5	0.4
Diabetes (mother)	1.8	2.3	4.8	0.7	2.2	1.2
Tinnitus: Yes, but not now, but have in the past	1.8	2.0	5.8	2.4	-0.3	0.0
Hayfever/allergic rhinitis (self-reported)	1.8	2.4	3.6	1.1	1.6	1.9
Neck or shoulder pain in last month	1.8	2.6	7.2	2.7	0.4	0.5
Long-standing illness, disability or infirmity	1.8	2.8	4.9	1.0	2.2	1.6
Average weekly champagne plus white wine intake	1.8	2.5	3.4	-1.5	-1.8	-1.4
Blood White Count	1.7	12.4	26.5	5.2	2.4	2.2
Severe depression (siblings)	1.7	1.9	4.8	2.2	0.9	0.3
Stomach or abdominal pain in last month	1.7	2.1	6.3	2.5	-0.2	-0.3
Number of live births	1.7	2.4	4.8	0.2	1.6	2.2
Number of children fathered	1.7	1.9	3.5	0.2	1.9	1.5
Ever had stillbirth, spontaneous miscarriage or termination	1.7	1.8	2.9	1.5	0.2	1.7
Myopia	1.7	2.4	7.1	-2.7	-0.3	-0.2
Vitamin and mineral supplements	1.6	2.2	4.5	-0.5	-2.1	-1.3
Ever unenthusiastic/disinterested for a whole week	1.6	2.0	3.0	1.5	1.7	0.8
Frequency of tiredness / lethargy in last 2 weeks	1.6	2.5	7.1	2.7	-0.2	-0.7
Mouth/teeth dental problems: Bleeding gums	1.6	2.1	2.6	1.2	1.6	1.5
Heart disease (mother)	1.6	1.9	2.8	-0.8	1.7	1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	1.5	2.0	5.0	2.2	0.9	0.3
Taking other prescription medications	1.5	2.3	5.3	0.9	2.3	1.0
Alcohol usually taken with meals	1.5	2.4	6.1	-2.5	-0.1	1.1
Financial difficulties in last 2 years	1.5	2.0	3.8	1.9	0.3	1.5
Loud music exposure frequency	1.5	1.6	3.8	1.9	0.9	0.4
Qualifications: O levels/GCSEs or equivalent	1.5	2.4	5.9	-2.4	-1.0	-0.4
Number of self-reported non-cancer illnesses	1.5	2.6	5.3	0.4	2.3	1.5
Wears glasses or contact lenses	1.5	1.7	3.6	-1.9	-0.6	-1.1
Ever taken oral contraceptive pill	1.5	1.7	3.3	0.8	-1.8	-1.1
Medication: Atorvastatin	1.5	1.8	2.3	1.5	1.5	1.0
Body Mass Index (BMI) (2010)	1.4	1.9	5.5	2.4	-0.1	-0.4
Triglycerides	1.4	2.2	6.5	2.5	0.1	0.4
Systolic blood pressure, automated reading	1.4	4.0	12.0	-3.5	-0.1	-0.1
Impedance of arm (right)	1.4	6.7	11.8	-3.4	-1.9	-2.2
Pulse rate	1.4	2.3	4.4	2.1	1.5	0.7
Glaucoma (self-reported)	1.4	1.7	2.6	-0.5	1.6	1.5
Shortness of breath walking on level ground	1.4	1.6	4.1	2.0	0.3	0.8
Knee pain experienced in last month	1.4	2.2	4.9	2.2	-0.6	-1.2
Hearing aid user	1.4	1.5	2.6	0.8	1.6	1.2
Systolic Blood Pressure	1.3	6.3	13.9	-3.7	-1.5	-1.7
Medication: Co-codamol	1.3	1.5	4.3	2.1	0.2	-0.1
Hair/balding pattern: Pattern 3	1.3	2.0	3.0	-1.7	0.4	1.6
Impedance of arm (left)	1.3	5.9	10.6	-3.3	-1.8	-1.9
Blood clot in the leg (DVT)	1.3	1.7	2.6	-0.5	-1.6	-1.5
Medication: Omeprazole	1.3	1.5	3.3	0.7	1.8	0.9
Illnesses of siblings: Diabetes	1.3	1.6	2.2	1.5	1.5	0.5
Loneliness, isolation	1.3	1.8	4.4	2.1	0.8	-0.6
Diabetes diagnosed by doctor	1.3	2.1	5.5	0.4	2.4	0.7
Mouth/teeth dental problems: Mouth ulcers	1.3	2.0	4.8	2.2	-0.2	-1.2
Financial situation satisfaction	1.3	1.6	2.3	1.5	0.8	1.4
Alcohol drinker status: Never	1.3	1.5	1.7	-1.0	-1.3	-1.3
Medication: Omeprazole (e.g. Zanprol)	1.3	1.5	2.9	1.2	1.7	0.6
Deep venous thrombosis (DVT) (self-reported)	1.3	1.6	2.4	-0.6	-1.6	-1.4
LDL Cholesterol	1.2	1.9	3.2	1.8	0.9	1.3
BMI	1.2	7.2	16.8	4.1	1.6	1.5
Medication: Atenolol	1.2	1.4	3.1	-1.8	-0.8	-0.8
Body mass index (BMI)	1.2	5.2	9.9	3.1	1.8	1.6
Waist circumference	1.2	4.5	11.0	3.3	1.0	1.2
Hair/balding pattern: Pattern 2	1.2	1.5	4.0	2.0	0.3	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.8	4.0	1.9	-2.0	-1.9
Peak expiratory flow (PEF)	1.2	2.7	7.6	2.8	-0.5	-0.5
Mineral and other dietary supplements	1.2	1.7	3.0	-1.2	-1.7	-0.7
Unable to work because of sickness or disability	1.2	1.5	2.1	1.4	-0.7	-1.4
Pack years of smoking	1.2	1.7	3.9	2.0	0.6	0.9
Leg fat mass (left)	1.2	4.6	9.9	3.1	1.6	1.2
Bipolar Disorder or Schizophrenia	1.1	2.6	5.0	2.2	1.0	1.3
Primary Biliary Cirrhosis	1.1	1.6	3.3	0.8	-1.8	-0.8
Pack years adult smoking proportion	1.1	1.7	4.0	2.0	0.6	0.9
High blood pressure (mother)	1.1	1.5	2.0	-1.4	-0.7	-1.4
Lung cancer (father)	1.1	1.3	2.3	0.1	-1.5	-1.3
Emphysema/chronic bronchitis	1.1	1.2	1.6	1.1	1.3	0.9
Medication: Allopurinol	1.1	1.4	1.7	1.1	1.1	1.3
Leg fat mass (right)	1.1	4.4	8.5	2.9	1.8	1.3
Chest pain or discomfort	1.1	1.7	3.3	0.3	1.8	1.2
Medication: Aspirin	1.1	1.4	1.8	1.4	1.1	1.1
Commuting to job workplace: Walk	1.1	1.2	1.7	-1.3	-1.0	-1.0
Illnesses of father: None of the above (group 1)	1.1	1.3	2.8	-0.7	-1.7	-0.8
Medication: Blood pressure	1.1	2.0	5.4	-2.3	-0.1	0.8
Impedance of whole body	1.1	5.4	8.1	-2.9	-1.8	-2.2
Depression (Nagel 2018)	1.0	1.6	3.3	1.8	0.9	0.8
Type 2 Diabetes (T2D) (2018)	1.0	1.9	4.1	0.6	2.0	1.2
Diabetes (father)	1.0	1.2	3.2	1.8	0.5	0.5
Fed-up feelings	1.0	1.8	2.9	1.7	1.0	1.2
Falls in the last year	1.0	1.3	3.9	2.0	-0.1	-0.2
Gout (self-reported)	1.0	1.4	2.1	1.1	1.4	0.9
Leg fat percentage (right)	1.0	3.7	4.5	2.1	2.1	1.5
Arm predicted mass (right)	1.0	5.3	12.8	3.6	1.0	1.4
Qualifications: nursing, teaching	1.0	1.5	4.4	-2.1	-0.1	0.4
Depressed Affect (Nagel 2018)	0.9	1.9	2.2	1.2	1.5	1.4
Rheumatoid Arthritis	0.9	1.3	2.7	0.0	-1.6	-1.1
Relative age of first facial hair	0.9	1.8	4.1	-2.0	-0.4	-1.1
Medication: Metformin	0.9	1.3	2.7	0.9	1.6	0.5
Leg fat-free mass (left)	0.9	5.0	13.3	3.6	0.6	1.1
Impedance of leg (left)	0.9	4.2	5.8	-2.1	-1.6	-2.4
Leg predicted mass (left)	0.9	4.8	12.7	3.6	0.7	1.1
Asthma	0.9	1.8	2.1	-1.2	1.4	1.3
Breastfed as a baby	0.9	1.1	2.2	-0.6	0.9	1.5
Forced vital capacity (FVC), Best measure	0.9	3.2	4.4	1.4	-2.1	-1.8
Arm fat-free mass (right)	0.9	4.8	12.5	3.5	0.7	1.1
Whole body fat mass	0.9	3.7	9.0	3.0	1.2	0.8
Leg fat-free mass (right)	0.9	4.7	13.9	3.7	-0.1	0.6
Leg predicted mass (right)	0.9	5.0	14.6	3.8	-0.1	0.6
Arm fat mass (left)	0.9	3.8	8.2	2.9	1.3	1.3
Basal metabolic rate	0.9	4.7	13.0	3.6	0.5	0.9
Leg fat percentage (left)	0.9	3.4	6.1	2.5	1.7	1.1
Schizophrenia (2018)	0.8	1.7	2.6	1.6	1.2	1.0
Alzheimer’s Disease (in mother)	0.8	1.0	2.4	-1.5	-0.0	0.7
Reaction Time	0.8	1.6	4.5	-2.1	-0.5	-0.0
Hearing difficulty/problems with background noise	0.8	1.3	3.9	2.0	0.3	-0.2
Medication: Simvastatin	0.8	1.2	2.0	-0.4	1.4	1.2
Illnesses of siblings	0.8	1.1	2.2	0.0	-1.5	-1.0
Weight	0.8	4.0	10.3	3.2	0.9	0.9
Father’s age at death	0.8	1.1	1.7	-0.0	-1.3	-1.3
Forced expiratory volume in 1-second (FEV1)	0.8	2.7	5.3	2.3	-1.3	-1.0
Arm fat mass (right)	0.8	3.4	8.4	2.9	1.1	0.9
Worry too long after embarrassment	0.8	1.4	3.7	0.6	-0.2	-1.9
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	1.7	1.3	-0.2	-1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	1.8	-0.9	1.4	-0.1
Medication: Aspirin	0.8	1.0	1.5	1.2	0.9	0.9
Mother’s age at death	0.8	1.0	2.1	-1.4	0.1	-0.9
Arm predicted mass (left)	0.8	3.9	10.2	3.2	0.7	1.0
Bipolar Disorder (2018)	0.7	1.1	2.5	1.6	0.2	0.8
Schizophrenia (2014)	0.7	1.5	4.4	2.1	-0.0	0.0
Average weekly spirits intake	0.7	0.8	1.5	0.5	1.2	0.8
Ever used hormone-replacement therapy (HRT)	0.7	0.9	1.5	0.3	1.2	1.1
Impedance of leg (right)	0.7	3.2	6.4	-2.5	-0.7	-1.6
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	2.1	0.5	1.4	0.5
Qualifications: None of the above	0.7	1.4	3.3	1.8	0.8	0.5
Time employed in main current job	0.7	0.8	2.0	-0.7	-0.3	-1.4
Depression (self-reported)	0.7	0.9	1.4	1.2	0.4	1.1
Headache pain in last month	0.7	1.3	3.5	1.9	0.2	0.5
Age at first live birth	0.7	1.3	2.1	-0.4	1.5	1.2
Whole body fat-free mass	0.7	4.2	11.6	3.4	0.5	1.0
Asthma (self-reported)	0.7	1.4	1.5	-1.2	1.2	1.1
Whole body water mass	0.7	4.1	11.6	3.4	0.2	0.8
Illnesses of father: High blood pressure	0.7	0.8	1.4	-0.7	1.2	0.7
Arm fat-free mass (left)	0.7	3.6	9.8	3.1	0.5	0.9
Age started oral contraceptive pill	0.7	0.9	1.7	-1.3	0.3	1.0
Major Depression (MDD)	0.6	0.8	1.3	1.1	-0.9	-0.3
Ovarian Cancer	0.6	0.8	1.2	-1.1	0.6	-1.0
Bipolar Disorder (2011)	0.6	0.5	0.9	0.9	0.1	0.9
Fasting Glucose	0.6	0.7	0.9	1.0	-0.7	0.9
Lupus	0.6	0.9	1.0	1.0	-0.9	-0.9
Lung FVC	0.6	2.9	8.4	2.9	-0.4	-0.2
Number of treatments/medications taken	0.6	1.1	2.3	-0.1	1.5	1.0
Trunk fat mass	0.6	2.6	6.9	2.6	0.8	0.3
Mouth/teeth dental problems	0.6	0.9	2.1	-1.5	-0.7	-0.3
Hip circumference	0.6	2.8	5.8	2.4	0.8	1.4
Length of working week for main job	0.6	0.6	1.4	0.7	-0.1	1.2
Birth weight of first child	0.6	1.2	1.6	1.2	-1.2	-0.7
Body fat percentage	0.6	2.4	5.0	2.2	1.3	0.6
Health satisfaction	0.6	0.8	1.2	1.1	0.8	0.7
Medication for pain relief, constipation, heartburn	0.6	1.0	2.7	-1.6	-0.3	-0.4
Arm fat percentage (left)	0.6	2.4	4.2	2.1	1.2	1.2
Tinnitus: Yes, now most or all of the time	0.6	0.7	1.7	1.3	0.4	0.5
High cholesterol (Self-reported)	0.6	1.0	1.6	0.2	1.2	1.3
Diastolic blood pressure, automated reading	0.6	1.7	3.5	-1.9	-1.0	-0.9
Ever depressed for a whole week	0.6	0.7	1.5	0.8	1.2	0.1
Verbal and Numeric Reasoning (VNR)	0.5	1.3	1.4	-1.2	-1.1	-1.1
Breast Cancer	0.5	1.3	2.3	1.5	-0.6	-1.1
Prostate Cancer	0.5	0.7	0.9	-0.8	0.9	0.8
Mean Putamen Volume	0.5	0.5	0.9	0.5	-0.6	-1.0
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.0	1.4	-0.2	-0.4
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	1.3	-1.1	0.3	0.5
Townsend deprivation index at recruitment	0.5	0.7	1.7	0.3	0.6	1.3
High blood pressure	0.5	1.4	3.1	-1.8	0.7	0.8
Multivitamins +/- minerals	0.5	0.7	1.5	0.5	1.2	0.5
Had other major operations	0.5	0.6	1.3	-1.1	0.2	0.6
Forced vital capacity (FVC)	0.5	1.9	3.7	1.9	-1.1	-0.8
Arm fat percentage (right)	0.5	1.9	3.6	1.9	1.1	1.0
Trunk fat-free mass	0.5	2.7	7.4	2.7	0.3	0.8
Qualifications: A levels/AS levels or equivalent	0.5	1.0	2.6	-1.6	-0.7	-0.0
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.4	-0.3	-1.2	-0.4
Illnesses of mother	0.5	0.6	1.7	1.3	-0.4	-0.1
Trunk predicted mass	0.5	2.6	7.1	2.7	0.3	0.7
Tense / ‘highly strung’	0.5	0.8	1.5	1.2	0.7	0.8
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.2	1.1	0.8	-0.3
Medication: Paracetamol	0.5	0.9	2.2	1.5	0.2	0.6
Medication: Ventolin 100micrograms inhaler	0.5	0.7	1.6	-1.3	0.3	0.5
Eye problems/disorders: None of the above	0.5	0.6	1.5	1.2	-0.0	-0.5
Pulse rate, automated reading	0.5	1.5	1.9	1.2	-1.0	-1.4
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.2	1.1	0.8	0.0
Ever had bowel cancer screening	0.5	0.6	1.5	0.3	1.2	0.5
Medication for cholesterol	0.5	0.7	2.1	1.4	0.3	0.0
Pain type(s) experienced in last month: Hip pain	0.5	0.7	1.9	1.4	0.3	-0.2
Risk taking	0.5	0.8	2.0	1.4	-0.1	0.6
Intelligence (Savage-Jansen 2018)	0.4	1.1	3.1	-1.8	-0.4	-0.2
HbA1C	0.4	0.4	0.9	0.0	-0.9	-0.7
HDL Cholesterol	0.4	0.7	1.7	-1.3	-0.1	-0.6
Waist Hip Ratio (WHR)	0.4	2.0	5.2	2.3	-0.8	-0.5
Respiratory disease	0.4	0.8	1.7	-1.3	0.6	0.5
Sensitivity / hurt feelings	0.4	0.7	1.1	0.9	-0.4	-1.1
Trunk fat percentage	0.4	1.6	4.2	2.1	0.7	0.1
Supplements: Glucosamine	0.4	0.5	1.3	1.2	0.4	0.0
Medication: Levothyroxine sodium	0.4	0.7	1.4	-0.8	1.2	0.4
Nervous feelings	0.4	0.7	1.0	0.4	-0.9	-1.0
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	1.4	1.2	-0.2	-0.8
Diabetes (self-reported)	0.4	0.6	1.8	0.1	1.4	-0.2
Happiness	0.4	0.5	1.0	1.0	0.5	0.4
Hair/balding pattern: Pattern 4	0.4	0.9	2.0	-0.3	-0.8	-1.4
Pulse wave reflection index	0.4	0.5	0.7	-0.8	0.4	0.8
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	0.9	0.8	-1.0	-0.6
Wheeze or whistling in the chest in last year	0.4	0.7	2.0	-0.3	1.4	0.3
Qualifications: College or University degree	0.4	1.3	3.5	-1.9	0.7	0.2
Family relationship satisfaction	0.4	0.5	1.0	0.6	1.0	0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	0.7	0.5	0.8	-0.7
Commuting to job workplace: Public transport	0.4	0.5	1.5	-1.2	-0.2	0.0
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.4	0.2	1.2	-0.2
Medication: Paracetamol	0.4	0.7	2.0	1.4	0.0	0.3
Vascular/heart problems diagnosed by doctor	0.4	1.0	2.6	1.6	-0.5	-0.5
Alcohol drinker status: Previous	0.4	0.4	0.8	0.3	0.6	0.9
Schizophrenia vs Biploar Disorder	0.3	0.3	0.8	0.9	-0.3	-0.3
Crohns Disease (2017)	0.3	0.6	1.4	0.6	1.2	-0.3
Ulcerative Colitis	0.3	0.5	0.7	0.8	-0.8	-0.5
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	1.0	1.0	-0.2	0.0
Pain all over the body in last month	0.3	0.3	0.8	-0.5	0.9	-0.0
Neuroticism score	0.3	0.7	1.8	1.4	0.5	0.0
Alcohol intake versus 10 years previously	0.3	0.5	1.3	1.1	0.2	-0.5
Medication: Amlodipine	0.3	0.4	0.6	-0.8	0.7	0.6
Birth weight	0.3	0.6	0.9	-0.2	-0.9	-0.9
Chronic bronchitis/emphysema (mother)	0.3	0.3	0.8	0.4	0.0	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.0	1.0	0.3	0.2
Medication: Blood pressure	0.3	0.5	1.4	-1.2	0.1	0.0
Medication: Ibuprofen	0.3	0.3	0.8	-0.0	0.5	0.9
Suffer from ‘nerves’	0.3	0.4	1.1	1.0	0.4	-0.1
Overall health rating	0.3	0.7	1.7	0.6	1.3	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.1	1.0	-0.1	0.4
Hypertension (Self-reported)	0.3	0.9	2.2	-1.5	0.4	0.6
Average weekly red wine intake	0.3	0.4	0.9	0.3	0.5	1.0
Breast cancer (self-reported)	0.3	0.3	0.6	0.2	-0.6	-0.8
Osteoarthritis (self-reported)	0.3	0.4	1.0	1.0	0.4	-0.1
Medication: Gliclazide	0.3	0.3	0.6	0.5	0.2	-0.8
Medication: Bendroflumethiazide	0.3	0.4	0.8	-0.9	-0.6	-0.2
Ever had prostate specific antigen (PSA) test	0.3	0.4	1.1	-0.1	1.0	-0.2
Basal cell carcinoma (self-reported)	0.3	0.4	0.6	-0.5	-0.5	-0.7
Neuroticism (Nagel 2018)	0.2	0.4	0.8	0.9	0.4	0.4
Worry (Nagel 2018)	0.2	0.3	0.4	0.7	-0.5	-0.5
Ulcerative Colitis (UC)	0.2	0.3	0.5	0.3	-0.7	-0.7
Coronary Artery Disease (CAD)	0.2	0.2	0.4	0.2	-0.7	-0.3
Crohns Disease (2012)	0.2	0.3	0.8	0.2	0.9	-0.1
Lung FEV1/FVC ratio	0.2	1.1	1.7	1.3	-0.7	-1.0
Neuroticism	0.2	0.5	1.2	1.1	0.4	0.3
Angina	0.2	0.2	0.5	-0.1	-0.3	-0.7
Sitting height	0.2	1.4	4.1	2.0	0.3	-0.2
Chronic bronchitis/emphysema (father)	0.2	0.3	0.7	-0.1	-0.9	0.2
Number of incorrect matches in round	0.2	0.3	0.8	-0.3	0.9	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.0	1.0	0.6	-0.0
Fluid intelligence score	0.2	0.4	0.7	-0.8	-0.4	-0.7
Mouth/teeth dental problems: Dentures	0.2	0.4	0.7	-0.8	-0.5	-0.3
Standing height	0.2	1.7	2.8	0.4	-1.7	-1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.4	0.6	0.7	-0.7	-0.0
Angina (self-reported)	0.2	0.3	0.7	-0.1	-0.3	-0.8
Migraine (self-reported)	0.2	0.2	0.5	0.2	0.4	-0.7
Medication: Seretide 50 evohaler	0.2	0.3	0.5	0.3	0.5	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	0.6	0.5	0.7	0.1
Number of full sisters	0.2	0.2	0.4	0.5	0.3	0.6
Eye problems/disorders: Cataract	0.2	0.3	0.7	-0.1	-0.8	-0.2
Osteoporosis (self-reported)	0.2	0.2	0.4	0.3	0.5	0.7
Irritable Bowel Disease (IBD)	0.1	0.2	0.6	0.3	0.0	-0.8
Neuroticism (2016)	0.1	0.1	0.3	-0.1	0.3	0.5
Blood Eosinophil Count	0.1	0.6	0.7	0.6	-0.7	-0.9
Blood Platelet Count	0.1	0.6	0.8	0.6	-0.9	-0.9
Blood Red Count	0.1	1.1	2.1	1.4	1.1	0.1
Heel T-Score	0.1	0.5	1.3	1.2	0.1	0.1
Height	0.1	1.7	3.0	-1.7	-1.2	-0.8
Cardiovascular Disease	0.1	0.4	0.9	-0.2	0.5	1.0
Hypothyroidism (self reported)	0.1	0.2	0.3	-0.4	0.5	0.3
Tanning	0.1	0.9	1.2	0.8	-1.0	-1.1
Hand grip strength (left)	0.1	0.3	0.6	0.8	-0.4	-0.4
Hand grip strength (right)	0.1	0.2	0.6	0.8	-0.3	0.1
Age when periods started (menarche)	0.1	0.2	0.3	0.4	0.5	-0.1
Hayfever, allergic rhinitis or eczema	0.1	0.1	0.3	0.6	0.2	-0.0
Heart attack	0.1	0.1	0.3	-0.6	-0.2	-0.1
Worrier / anxious feelings	0.1	0.2	0.4	0.6	-0.4	-0.0
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.2	0.3	0.2	0.5
Medication: Cholesterol lowering	0.1	0.2	0.6	0.1	0.7	-0.3
Medication: Lansoprazole	0.1	0.1	0.2	0.3	0.4	0.2
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	0.7	0.1	0.8	0.2
Pulse wave peak to peak time	0.1	0.1	0.2	-0.1	-0.3	-0.4
Alcohol intake frequency.	0.1	0.3	0.5	0.7	0.4	0.3
Leg pain on walking	0.1	0.1	0.2	-0.2	0.3	0.4
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.4	-0.1	-0.0	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.5	-0.2	-0.2	-0.7
Miserableness	0.1	0.1	0.3	0.6	-0.2	-0.0
Guilty feelings	0.1	0.2	0.2	0.5	0.5	-0.4
Medication: Lisinopril	0.1	0.2	0.2	-0.5	-0.3	-0.4
Number of operations (self-reported)	0.1	0.1	0.3	-0.3	0.6	0.2
Average weekly beer plus cider intake	0.1	0.1	0.3	-0.6	0.0	-0.3
Irritability	0.1	0.2	0.2	0.4	0.2	0.5
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.2	-0.5	-0.2	-0.3
Age at First Birth	0.0	0.1	0.1	-0.3	-0.2	-0.2
Allergy or Eczema	0.0	0.0	0.0	-0.0	0.1	0.1
Chronotype (morning person)	0.0	0.1	0.2	-0.1	-0.4	-0.2
Hair Pigment	0.0	0.3	0.7	0.1	-0.8	-0.2
Relative age voice broke	0.0	0.0	0.1	-0.3	0.0	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.2	0.2	0.4	0.1
Allergy	0.0	0.0	0.0	-0.0	-0.1	0.0
Medication: Ramipril	0.0	0.0	0.1	-0.2	-0.3	0.0
Prospective memory result	0.0	0.0	0.1	0.2	-0.2	-0.2
Pulse wave Arterial Stiffness index	0.0	0.0	0.0	0.1	0.0	0.1
High blood pressure (siblings)	0.0	0.1	0.1	-0.4	-0.2	-0.1
Comparative body size at age 10	0.0	0.0	0.1	-0.2	0.0	-0.3
Comparative height size at age 10	0.0	0.1	0.2	-0.1	0.1	0.4
Mood swings	0.0	0.0	0.1	-0.1	-0.1	0.3
Friendships satisfaction	0.0	0.0	0.0	0.2	0.2	0.1
Eye problems/disorders: Glaucoma	0.0	0.0	0.1	0.2	0.3	0.1

Hub : Genes

UBE2FP3

Models

Trait associations