Hub : Genes

UBE2R2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0490 0.0250 1.8e-03 0.016 0.014 0.003 0.012 0.005 3.6e-03 7.5e-03 1.3e-01 1.1e-02 6.6e-02
2 GTEx Cells Transformed fibroblasts 0.1450 0.0420 3.6e-06 0.052 NA 0.154 NA 0.139 9.0e-05 NA 1.2e-11 NA 1.4e-10
3 METSIM Adipose 0.0336 0.0163 4.0e-03 0.003 0.000 -0.002 0.003 -0.002 1.1e-01 3.3e-01 8.4e-01 9.6e-02 7.6e-01
4 ROSMAP Brain Pre-frontal Cortex 0.2157 0.0406 0.0e+00 0.199 0.192 0.205 0.210 0.203 5.4e-25 4.1e-24 7.2e-26 1.9e-26 1.3e-25
5 YFS Blood 0.0150 0.0071 3.8e-03 0.007 0.004 0.005 0.004 0.006 1.6e-03 1.5e-02 6.0e-03 1.0e-02 2.6e-03
6 TCGA Kidney Renal Clear Cell Carcinoma 0.0956 0.0756 1.9e-03 0.001 0.000 0.018 NA 0.004 2.4e-01 3.6e-01 4.0e-03 NA 9.9e-02
7 TCGA Prostate Adenocarcinoma 0.0429 0.0233 4.7e-04 0.008 0.024 0.019 NA 0.008 4.8e-02 1.3e-03 3.9e-03 NA 4.0e-02
8 TCGA Thyroid Carcinoma 0.0670 0.0320 5.6e-05 0.027 0.051 0.032 NA 0.039 1.0e-03 9.2e-06 3.9e-04 NA 9.9e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 1.8 2.8 5.0 -2.1 1.9 1.3 -0.8 1.2 -1.3 2.0 2.2
Bipolar Disorder or Schizophrenia 1.2 2.8 8.1 -2.2 1.8 1.3 -0.7 0.8 -0.3 1.9 2.9
Depressed Affect (Nagel 2018) 0.0 0.1 0.1 0.4 -0.3 0.3 0.4 0.1 0.0 0.1 0.0
Depression (Nagel 2018) 0.7 1.0 2.2 0.7 -1.0 -1.4 -1.0 1.5 -1.2 -0.4 -0.0
Intelligence (Savage-Jansen 2018) 1.9 5.9 9.3 0.1 -2.6 -2.5 -3.0 2.5 -2.4 -2.6 -2.5
Neuroticism (Nagel 2018) 0.1 0.1 0.3 -0.2 0.5 0.4 -0.3 0.4 -0.1 0.4 0.5
Schizophrenia (2018) 0.4 0.9 3.5 -1.1 0.8 0.6 -0.3 0.1 0.7 0.8 1.9
Schizophrenia vs Biploar Disorder 1.0 1.3 6.3 0.8 -0.3 0.2 0.3 -1.1 2.5 -1.5 0.1
Worry (Nagel 2018) 0.2 0.4 0.9 0.9 0.3 0.7 -0.1 -0.0 0.9 -0.2 0.8
Alzheimer’s Disease (in mother) 1.0 1.2 2.2 1.5 -1.4 -0.5 -0.9 0.7 -0.6 -1.5 -1.3
Alzheimer’s Disease (in father) 0.2 0.2 0.9 -0.0 0.5 0.9 -0.1 -0.5 0.2 0.3 0.1
Alzheimer’s Disease (including proxy) 0.3 0.4 1.2 1.1 -0.7 0.3 -0.5 -0.0 -0.1 -0.9 -0.6
Crohns Disease (2017) 0.5 1.2 3.2 0.6 -0.6 -0.9 -1.5 1.8 0.7 -1.3 -0.5
Irritable Bowel Disease (IBD) 0.9 2.1 5.7 0.5 -1.1 -1.3 -2.0 2.4 0.1 -1.7 -1.0
Ulcerative Colitis (UC) 0.6 1.2 2.7 0.4 -0.8 -0.9 -1.4 1.6 -0.3 -1.3 -1.1
Major Depression (MDD) 0.1 0.2 0.5 0.6 -0.7 -0.1 0.4 -0.3 -0.3 0.1 0.3
Reaction Time 0.1 0.3 0.9 0.7 0.7 0.0 1.0 -0.3 0.1 0.3 -0.1
Verbal and Numeric Reasoning (VNR) 2.0 4.7 6.9 0.4 -2.5 -2.1 -2.6 1.8 -1.9 -2.6 -2.6
Breast Cancer 0.3 0.7 3.5 -0.3 0.0 -0.2 -0.3 1.9 -0.3 -1.2 -0.6
Ovarian Cancer 2.6 3.4 6.2 -2.2 2.4 2.1 0.6 0.2 0.3 2.5 2.3
Prostate Cancer 5.8 8.2 11.6 3.4 -3.4 -3.2 -2.1 1.2 -2.4 -3.3 -3.2
Age at First Birth 1.4 2.0 4.3 1.2 -1.4 -1.3 -1.5 0.8 -0.5 -2.1 -2.0
Bipolar Disorder (2011) 1.3 1.2 3.4 -1.2 1.3 1.0 -0.7 0.6 -0.3 1.2 1.9
Body Mass Index (BMI) (2010) 7.9 10.8 17.3 -1.6 3.4 3.5 4.2 -3.8 2.6 3.5 3.0
Coronary Artery Disease (CAD) 0.8 0.9 2.8 -0.7 0.7 1.0 0.9 -1.7 -0.0 1.1 0.8
Crohns Disease (2012) 0.3 0.4 0.9 0.2 0.2 -0.5 -0.9 0.9 1.0 -0.8 0.3
Mean Putamen Volume 2.4 2.8 4.5 1.5 -1.3 -1.9 -1.5 2.1 -1.9 -1.4 -1.5
Fasting Glucose 0.3 0.3 1.1 0.2 -0.6 0.6 0.3 -0.4 0.1 0.8 1.0
HbA1C 1.3 1.5 4.3 -0.3 1.1 0.2 0.8 -2.1 1.1 1.0 1.8
HDL Cholesterol 1.1 1.9 3.6 0.4 -0.8 -1.0 -1.7 1.9 -1.1 -1.4 -1.8
LDL Cholesterol 0.4 0.6 1.8 0.2 -0.8 -0.9 -0.2 0.8 -1.4 -0.4 -0.7
Lupus 0.3 0.4 1.3 -0.4 -0.0 1.1 -0.4 0.4 0.3 1.0 0.5
Neuroticism (2016) 0.1 0.1 0.5 -0.1 0.7 -0.0 -0.1 0.1 0.1 -0.1 0.2
Primary Biliary Cirrhosis 0.2 0.2 1.3 -0.3 0.3 -0.3 -0.1 0.3 0.2 -0.5 -1.1
Rheumatoid Arthritis 0.2 0.3 0.8 -0.3 0.9 0.8 0.7 -0.2 -0.2 -0.1 -0.4
Schizophrenia (2014) 0.4 0.8 2.4 -0.9 0.7 0.5 -1.2 0.8 0.1 0.4 1.6
Triglycerides 5.5 9.0 13.8 -3.0 2.7 2.2 3.3 -3.5 2.2 3.0 3.7
Type 2 Diabetes (T2D) (2012) 6.6 7.6 14.5 -3.8 2.7 2.4 1.9 -3.1 1.9 3.3 2.3
Ulcerative Colitis 0.8 1.1 2.7 -0.2 -1.2 -0.2 -1.6 1.6 0.3 -1.4 -0.4
Blood Eosinophil Count 1.0 7.4 21.2 -4.6 1.5 3.2 1.9 -1.6 0.7 3.8 2.2
Blood Platelet Count 1.2 13.4 27.0 -1.7 4.7 3.7 5.2 -4.6 2.5 3.3 2.1
Blood Red Count 0.3 3.1 12.2 -3.5 0.7 2.1 -1.5 0.8 -0.8 1.5 1.4
Blood White Count 1.4 10.7 20.1 -3.9 4.1 4.5 1.4 -1.4 1.5 4.0 3.4
Heel T-Score 1.3 10.5 24.2 -4.4 3.3 4.0 1.1 -3.3 0.1 4.9 1.2
BMI 4.5 26.2 38.3 -3.7 6.2 6.0 6.0 -3.4 4.6 5.6 4.5
Height 1.4 27.9 39.2 3.0 -5.5 -5.3 -6.2 6.3 -5.7 -4.8 -4.8
Waist Hip Ratio (WHR) 0.6 2.5 9.6 -0.3 0.5 -0.6 -1.6 2.4 -3.1 1.2 -0.0
Systolic Blood Pressure 0.5 2.5 9.3 1.4 1.1 0.1 2.0 -1.4 0.9 0.1 3.0
Smoking Status 2.8 6.7 12.9 2.1 -2.2 -1.7 -3.6 2.6 -2.4 -2.5 -3.1
Allergy or Eczema 0.4 1.0 2.7 0.2 0.4 0.5 1.6 -0.7 0.2 1.7 1.4
Cardiovascular Disease 1.1 3.7 9.7 -0.5 2.2 1.5 2.5 -1.7 1.2 1.4 3.1
Hypothyroidism (self reported) 0.1 0.3 0.9 0.2 0.4 -0.2 0.2 -0.1 -0.6 0.9 0.9
Respiratory disease 1.4 3.1 8.3 -1.1 2.0 2.1 0.9 0.5 -0.1 2.9 2.4
Type 2 Diabetes (T2D) (2018) 0.8 1.5 4.9 -1.1 1.6 1.2 0.7 0.9 -0.4 2.2 0.6
Lung FEV1/FVC ratio 3.1 15.7 29.8 -2.5 4.0 3.1 4.9 -5.2 5.5 2.5 2.7
Lung FVC 1.0 5.0 15.1 0.7 -1.2 -2.0 -3.9 3.1 -2.4 -1.6 -1.2
Neuroticism 0.2 0.4 1.4 0.4 0.0 0.0 -1.2 0.9 0.4 -0.5 0.2
Chronotype (morning person) 2.8 6.4 11.8 -1.6 3.4 2.2 3.1 -2.5 2.1 2.4 2.4
Hair Pigment 0.0 1.3 6.2 0.1 0.5 -0.0 -1.4 0.6 -1.2 0.4 -2.5
Tanning 0.1 1.0 4.8 2.2 -0.7 0.0 1.2 -0.8 -0.0 0.2 -0.7
Hand grip strength (left) 3.5 9.3 13.5 3.6 -3.7 -3.2 -3.0 2.9 -1.9 -3.5 -1.9
Number of treatments/medications taken 1.4 2.5 6.7 -0.9 2.0 1.6 0.6 -0.8 1.3 1.9 2.6
Average weekly spirits intake 0.3 0.4 0.8 -0.0 0.8 0.9 0.9 -0.2 0.5 0.4 0.7
Sensitivity / hurt feelings 0.6 1.0 4.8 -0.4 1.3 0.0 -0.9 0.1 0.3 0.7 2.2
Frequency of depressed mood in last 2 weeks 1.3 1.9 3.3 0.8 -0.9 -1.8 -1.8 1.6 -1.8 -0.8 -1.0
Hearing difficulty/problems: Yes 0.1 0.2 0.7 0.2 -0.0 0.1 -0.8 0.8 -0.7 0.1 -0.1
Relative age of first facial hair 0.3 0.7 3.6 0.5 -1.9 -0.3 -0.3 0.2 -0.4 -0.0 -1.1
Other serious medical condition/disability diagnosed by doctor 1.3 1.6 3.6 -1.5 0.9 1.9 0.3 -0.1 0.4 1.6 1.9
Ever used hormone-replacement therapy (HRT) 1.4 1.8 5.4 -2.3 1.1 1.3 0.2 -1.0 0.2 2.1 0.8
Ever had hysterectomy (womb removed) 0.1 0.2 0.8 0.0 -0.0 0.3 0.1 0.4 0.9 0.3 -0.0
Systolic blood pressure, automated reading 2.4 7.1 14.6 -0.1 2.8 2.3 3.4 -2.6 2.8 1.7 3.8
Eye problems/disorders: Diabetes related eye disease 0.4 0.4 2.0 0.4 -0.4 -0.5 -0.6 1.4 -0.2 0.2 0.5
Angina 0.5 0.6 3.6 0.0 0.8 0.7 0.3 0.3 1.9 -0.3 0.4
Medication for hormone replacement therapy 0.6 0.7 1.7 -0.6 1.2 0.7 0.3 0.2 0.5 0.9 1.3
Vitamin and mineral supplements 1.8 2.5 5.8 2.3 0.7 0.4 2.0 -1.5 2.4 -1.4 0.3
Supplements: Zinc 0.8 0.8 1.9 -1.1 0.8 1.1 0.7 -1.0 0.2 1.4 0.3
Medication: Co-codamol 1.1 1.2 2.4 0.5 1.5 0.7 1.6 -1.0 1.5 0.2 1.2
Medication: Metformin 0.8 1.1 3.1 -0.8 1.8 0.6 0.8 0.1 0.8 1.7 0.9
Diabetes (father) 0.8 0.9 2.3 0.3 1.1 0.4 1.5 -1.1 -0.6 1.4 0.0
Diabetes (mother) 1.4 1.8 3.6 -1.6 1.5 1.9 1.1 0.1 0.4 1.7 1.1
Severe depression (siblings) 0.6 0.7 2.6 0.3 0.2 -0.9 -0.7 -0.7 1.6 -1.0 0.3
Pack years adult smoking proportion 1.5 2.3 4.8 2.2 -1.6 -1.6 -0.4 1.1 -1.5 -1.6 -1.4
Impedance of leg (right) 3.4 16.4 23.7 2.7 -4.7 -4.7 -4.3 3.5 -3.3 -4.9 -3.8
Leg fat-free mass (left) 0.9 4.7 10.0 -2.0 2.7 2.5 2.2 -1.0 1.0 3.2 1.9
Trunk fat percentage 0.6 2.4 6.2 -1.7 2.5 2.0 0.8 -0.1 1.5 1.7 0.3
Hand grip strength (right) 4.1 11.2 14.3 3.6 -3.8 -3.8 -3.2 3.4 -2.9 -3.5 -2.4
Townsend deprivation index at recruitment 0.2 0.3 1.7 1.3 0.1 -0.4 0.1 0.2 -0.4 0.4 0.6
Current tobacco smoking 1.8 3.0 5.3 1.8 -1.3 -0.9 -2.1 1.9 -1.3 -2.3 -1.7
Average weekly fortified wine intake 0.7 0.9 5.2 -2.3 -0.4 0.4 -0.4 -0.9 0.2 0.6 0.2
Maternal smoking around birth 0.9 1.3 6.1 0.1 -1.0 -0.8 -0.5 0.7 -2.5 -0.2 -1.3
Fed-up feelings 0.6 1.0 1.7 0.9 -1.1 -0.8 -1.0 0.8 -1.3 -1.0 -1.0
Frequency of unenthusiasm / disinterest in last 2 weeks 0.7 0.9 3.0 0.7 -0.5 -1.3 -0.2 1.2 -1.7 -0.2 -0.0
Relative age voice broke 0.8 1.2 2.2 -0.9 0.1 1.4 1.5 -1.2 0.9 1.5 0.4
Taking other prescription medications 0.3 0.5 1.4 0.8 0.1 1.0 -0.5 0.4 -0.1 0.8 1.2
Age when periods started (menarche) 0.4 1.0 3.3 1.2 -0.7 -0.5 -0.3 1.8 -1.3 -0.3 -0.5
Bilateral oophorectomy (both ovaries removed) 1.1 1.3 3.1 0.7 -1.3 -1.0 -1.5 1.8 -0.5 -0.4 -1.1
Heel bone mineral density (BMD) T-score, automated (left) 0.9 2.1 7.7 -2.8 1.0 1.6 -0.3 -0.5 1.0 2.0 -0.3
Tinnitus: Yes, but not now, but have in the past 1.4 1.5 3.2 -0.7 1.1 1.0 1.1 -1.6 0.1 1.6 1.8
Qualifications: CSEs or equivalent 0.1 0.2 0.5 0.1 -0.0 -0.1 -0.5 -0.6 -0.4 -0.7 -0.5
Serious illness, injury or assault to yourself 0.3 0.3 0.8 -0.9 0.7 0.2 0.5 -0.5 0.7 0.4 0.2
High blood pressure 2.1 5.8 13.4 -1.0 3.0 2.2 2.7 -1.5 2.0 2.1 3.7
Hayfever, allergic rhinitis or eczema 0.3 0.7 2.3 0.6 -0.5 -0.3 1.5 -1.0 0.2 0.9 0.7
Multivitamins +/- minerals 2.2 2.9 12.4 -3.5 0.7 1.0 -0.0 0.0 -1.1 2.6 0.9
Stomach or abdominal pain in last month 0.3 0.3 1.8 -0.1 -0.5 -0.5 0.1 -0.4 -1.3 -0.3 0.1
Supplements: Glucosamine 3.3 4.3 9.8 -0.6 1.2 1.7 2.6 -3.1 3.0 1.5 1.3
Diverticular disease/diverticulitis (self-reported) 0.4 0.5 1.1 -0.6 0.5 1.0 0.3 -1.0 0.5 0.8 0.7
Medication: Atenolol 0.4 0.5 1.2 0.2 0.0 -0.6 -0.9 1.1 -0.5 -1.1 -0.5
Medication: Levothyroxine sodium 0.3 0.5 2.0 0.5 0.6 -0.1 0.5 0.8 0.4 0.6 1.4
Sitting height 0.7 4.9 10.4 0.1 -2.2 -1.5 -2.9 3.2 -2.9 -1.7 -1.4
Chronic bronchitis/emphysema (father) 0.9 1.0 2.9 1.1 -0.9 -0.7 -1.7 1.2 -1.1 -0.2 -0.0
High blood pressure (mother) 0.4 0.6 3.8 -0.2 -0.2 0.0 -0.9 2.0 -0.1 -0.3 0.3
Body mass index (BMI) 2.9 12.4 20.7 -2.5 4.5 4.2 3.7 -2.4 3.1 4.1 2.9
Impedance of leg (left) 3.9 19.0 29.7 3.3 -5.1 -4.9 -4.5 3.5 -3.3 -5.5 -4.3
Leg predicted mass (left) 0.9 4.6 9.8 -1.9 2.6 2.5 2.2 -0.9 0.9 3.1 1.9
Trunk fat mass 0.8 3.6 7.6 -2.0 2.8 2.5 1.4 -0.2 1.5 2.3 0.9
Waist circumference 2.0 7.5 15.4 -2.7 3.9 3.4 2.3 -1.0 0.8 3.9 1.9
Number of incorrect matches in round 1.0 1.7 5.0 -1.5 1.3 0.7 0.5 0.4 0.3 1.8 2.2
Past tobacco smoking 1.4 2.6 7.3 -0.9 1.1 1.0 2.7 -2.0 1.4 0.8 1.9
Alcohol usually taken with meals 0.4 0.6 1.8 -0.2 -0.7 -0.7 -0.4 1.3 0.0 -0.9 -1.2
Nervous feelings 0.4 0.8 2.2 1.0 -0.9 -0.7 -1.5 0.7 0.5 -1.1 -0.0
Frequency of tenseness / restlessness in last 2 weeks 0.7 1.0 2.9 1.2 -0.4 -0.8 -1.0 1.7 -1.2 -0.4 -0.6
Hearing difficulty/problems with background noise 0.7 1.2 2.8 -1.6 1.7 1.1 -0.5 0.3 -0.2 1.2 1.1
Hair/balding pattern: Pattern 2 2.9 3.7 7.9 -1.4 2.1 1.9 1.9 -1.3 1.5 2.0 2.8
Had menopause 1.7 2.2 3.7 -1.3 1.3 1.2 1.8 -1.3 1.6 1.9 1.2
Had other major operations 0.7 0.8 3.4 0.8 -0.2 -1.0 -0.5 0.4 -1.8 -0.0 -0.9
Forced vital capacity (FVC) 3.1 11.9 22.5 1.1 -3.2 -3.0 -4.6 4.7 -4.2 -2.4 -2.7
Heel bone mineral density (BMD) T-score, automated (right) 1.2 2.9 10.0 -3.2 1.7 1.8 0.2 -1.1 1.2 2.0 0.1
Ever unenthusiastic/disinterested for a whole week 2.1 2.6 4.9 1.5 -2.2 -2.2 -1.5 0.8 -0.4 -2.0 -1.4
Qualifications: None of the above 1.2 2.6 6.0 0.3 1.6 0.5 2.2 -2.4 1.0 1.0 2.2
Financial difficulties in last 2 years 0.2 0.2 0.8 0.6 -0.4 -0.4 0.0 0.9 0.4 -0.4 0.2
Mouth/teeth dental problems 0.1 0.1 0.6 0.7 -0.2 -0.3 0.0 0.2 0.1 -0.1 0.2
Heart attack 0.5 0.7 2.0 0.5 -0.7 -0.8 -1.1 1.4 0.2 -0.9 -0.0
Allergy 0.7 1.5 3.1 0.4 -0.8 -1.3 -1.8 0.7 -0.8 -1.7 -1.6
Pain all over the body in last month 1.0 1.1 4.4 2.1 -0.5 -1.3 -0.7 0.7 -0.3 -1.1 -0.1
Diabetes (self-reported) 0.7 1.2 3.9 -1.2 2.0 0.9 0.2 0.9 0.1 1.4 0.6
Hayfever/allergic rhinitis (self-reported) 1.3 1.7 3.8 0.2 1.2 0.9 1.9 -1.8 1.3 1.1 1.1
Medication: Ramipril 0.3 0.4 1.2 0.5 0.3 -0.4 -0.8 1.1 0.1 -0.7 -0.3
Medication: Simvastatin 0.2 0.3 0.9 0.6 0.6 -0.2 -0.3 -0.6 0.9 -0.7 0.5
Fluid intelligence score 3.1 6.4 9.2 1.3 -2.9 -2.1 -3.0 2.8 -1.8 -3.0 -2.8
Illnesses of siblings 0.5 0.7 1.6 -0.2 -0.8 -0.5 -0.2 1.0 -1.1 -0.6 -1.2
Neuroticism score 0.3 0.6 1.4 1.0 -0.5 -0.6 -1.2 1.2 -0.3 -0.7 -0.2
Weight 0.8 3.8 7.0 -1.8 2.5 2.6 1.8 -0.5 1.2 2.6 1.3
Impedance of arm (right) 2.2 10.1 18.2 0.2 -2.8 -3.5 -4.3 3.4 -3.1 -2.9 -3.5
Arm fat percentage (right) 2.3 9.1 17.6 -3.2 4.2 3.7 2.4 -1.4 2.3 3.8 2.0
Trunk fat-free mass 0.2 1.1 3.1 -0.9 0.6 1.6 0.9 0.4 -0.3 1.8 1.0
Hip circumference 1.1 4.9 9.3 -2.5 2.9 3.0 2.0 -1.0 1.6 2.6 0.9
Time employed in main current job 1.6 1.8 3.6 0.5 -1.9 -1.9 -1.7 0.7 -0.3 -1.7 -0.8
Alcohol intake versus 10 years previously 0.1 0.1 0.6 -0.3 0.8 0.1 -0.2 -0.3 -0.0 -0.0 -0.2
Father’s age at death 0.7 0.9 2.0 -1.2 0.5 1.0 1.0 1.1 0.2 1.4 0.6
Worrier / anxious feelings 0.2 0.4 1.4 0.1 0.5 1.2 -0.3 0.6 0.7 -0.3 0.6
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.8 2.1 0.8 -0.5 -0.6 -0.5 1.5 -1.4 -0.5 -0.3
Falls in the last year 1.2 1.7 3.3 -1.4 1.1 1.2 1.7 -0.2 1.0 1.8 1.1
Hair/balding pattern: Pattern 3 5.7 8.5 15.6 3.3 -3.1 -3.2 -1.7 2.1 -2.6 -2.7 -4.0
Number of live births 2.5 3.5 5.6 -1.0 2.4 1.9 2.1 -1.7 1.3 1.8 2.3
Forced expiratory volume in 1-second (FEV1) 1.3 4.4 8.5 -0.1 -1.7 -2.1 -2.9 2.9 -2.6 -1.4 -1.5
Pulse rate 0.3 0.5 2.8 0.2 0.2 -0.3 -1.7 0.5 -0.7 -0.1 -0.6
Happiness 1.2 1.4 3.8 1.3 -1.1 -1.9 -1.2 1.4 -0.8 -1.0 -0.3
Noisy workplace 1.2 1.5 2.7 -1.4 1.7 1.5 1.0 -1.0 0.8 1.2 1.0
Qualifications: A levels/AS levels or equivalent 0.7 1.5 4.3 0.4 -2.1 -1.1 -1.2 1.1 -1.0 -1.1 -1.4
Serious illness, injury or assault of a close relative in last 2 years 1.3 1.5 5.0 0.1 -1.0 -1.1 -1.0 1.5 -2.2 -0.4 -1.2
Mouth/teeth dental problems: Dentures 1.8 3.0 5.5 -1.2 2.1 2.3 1.8 -1.0 0.7 2.3 1.5
Asthma 1.1 2.1 5.2 -1.6 1.7 2.0 0.7 0.1 -0.3 2.3 1.3
Medication: Ibuprofen (e.g. Nurofen) 0.2 0.3 1.2 -0.3 -0.1 -0.4 0.1 -0.1 -1.1 0.9 0.1
Medication: Cholesterol lowering 0.5 0.7 2.5 0.2 0.9 0.1 -0.1 -0.3 1.4 -0.5 1.6
Depression (self-reported) 0.2 0.3 1.0 0.1 -0.5 -0.7 -1.0 0.7 -0.0 -0.3 0.4
Medication: Lansoprazole 0.4 0.4 1.3 1.1 0.4 0.9 0.9 -0.0 0.4 -0.2 0.0
Prospective memory result 2.3 2.8 5.4 0.4 1.6 1.0 2.3 -2.3 1.6 1.4 1.8
Lung cancer (father) 0.3 0.4 0.9 0.9 0.7 0.4 0.5 0.6 1.0 -0.3 0.3
Illnesses of mother 0.4 0.5 1.0 0.5 -0.9 -1.0 -0.6 -0.1 -0.5 -0.6 -1.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.9 2.7 6.1 0.1 -1.1 -1.6 -2.4 2.1 -2.5 -0.9 -1.1
Pulse wave Arterial Stiffness index 0.3 0.3 1.1 -0.5 -0.0 0.2 -1.0 0.4 -0.8 0.0 -0.7
Impedance of arm (left) 2.4 11.2 18.7 1.0 -3.0 -3.8 -4.3 3.0 -2.8 -3.7 -4.0
Arm fat mass (right) 1.9 7.7 15.2 -2.6 3.9 3.5 2.4 -1.3 2.0 3.5 1.8
Trunk predicted mass 0.2 1.1 3.1 -0.9 0.6 1.6 0.8 0.4 -0.3 1.8 1.0
Standing height 1.2 11.5 17.6 1.2 -3.9 -2.9 -4.0 4.2 -3.9 -2.7 -3.3
Length of working week for main job 0.2 0.2 0.7 0.0 0.1 -0.1 -0.2 -0.7 -0.7 0.8 -0.2
Exposure to tobacco smoke at home 0.3 0.3 1.7 -0.1 0.6 0.3 -0.1 0.3 1.3 0.3 0.2
Breastfed as a baby 0.4 0.6 1.3 -0.9 0.3 -0.5 -0.9 0.9 -1.1 -0.5 0.3
Tense / ‘highly strung’ 0.3 0.5 1.3 0.4 1.0 0.3 0.6 -0.5 1.2 0.2 1.0
Seen doctor (GP) for nerves, anxiety, tension or depression 0.4 0.6 1.2 -0.8 0.2 -1.1 -0.8 0.0 -1.1 0.8 0.8
Hair/balding pattern: Pattern 4 2.6 6.2 10.5 -2.3 2.7 2.4 1.9 -2.0 2.7 2.5 3.2
Birth weight of first child 0.2 0.4 2.1 0.1 -0.2 0.7 0.7 -0.4 1.4 -0.3 0.4
Peak expiratory flow (PEF) 1.5 3.5 6.3 -0.5 -2.1 -2.2 -2.5 2.0 -2.5 -0.8 -0.9
Pulse wave reflection index 0.3 0.4 1.2 -1.1 0.4 1.1 0.2 0.1 0.0 0.5 0.4
Ever highly irritable/argumentative for 2 days 0.1 0.2 0.9 -0.0 0.0 0.1 0.5 -0.4 -0.2 0.2 0.9
Loud music exposure frequency 0.5 0.5 2.3 -0.2 0.3 0.4 0.5 0.3 -0.3 1.1 1.5
Qualifications: O levels/GCSEs or equivalent 1.2 1.9 5.2 0.3 -2.3 -0.8 -1.5 0.2 -0.2 -2.0 -1.7
Mouth/teeth dental problems: Bleeding gums 2.1 2.7 5.9 1.5 -2.4 -2.2 -1.5 0.2 -1.0 -2.0 -1.2
Blood clot in the leg (DVT) 0.8 1.0 2.5 -1.3 1.1 1.4 0.5 -0.1 -0.9 1.6 0.4
Medication: Paracetamol 0.1 0.2 0.5 0.4 0.5 -0.1 -0.7 0.4 0.0 -0.5 -0.2
Headache pain in last month 0.3 0.5 1.2 -0.8 0.1 1.1 -0.2 -0.6 -1.0 0.7 0.5
Medication for cholesterol, blood pressure or diabetes 0.6 0.9 4.0 -0.6 -1.1 -0.1 -0.5 0.6 -1.2 0.2 -2.0
Glaucoma (self-reported) 2.1 2.5 5.1 -0.6 2.3 1.5 1.5 -1.9 2.2 0.0 1.2
Gout (self-reported) 3.0 4.1 7.6 -2.2 2.6 1.5 1.8 -1.7 1.1 2.8 2.2
Hypothyroidism/myxoedema (self-reported) 0.4 0.8 2.7 0.5 0.8 0.2 1.0 -0.3 -0.1 1.3 1.6
Medication: Amlodipine 0.6 0.8 2.3 0.7 0.7 0.5 1.1 -0.9 1.5 0.3 1.0
Medication: Ventolin 100micrograms inhaler 0.4 0.5 1.4 -0.7 -0.1 0.1 -1.1 1.2 -0.5 0.7 0.4
Birth weight 1.7 3.6 6.7 2.5 -2.4 -1.5 -1.0 1.7 -0.5 -2.0 -2.6
Chronic bronchitis/emphysema (mother) 0.4 0.5 1.1 1.1 0.3 -0.3 1.0 -1.0 0.4 -0.5 0.1
High blood pressure (siblings) 0.3 0.4 1.4 0.8 -0.2 -0.7 -0.3 0.3 0.1 0.4 1.2
Forced vital capacity (FVC), Best measure 2.7 9.8 19.2 0.7 -2.5 -2.6 -4.3 4.0 -4.4 -2.0 -2.6
Body fat percentage 0.9 3.7 7.7 -2.0 2.8 2.5 1.6 -0.6 1.8 2.2 0.8
Leg fat percentage (right) 1.6 5.8 9.6 -1.8 3.1 2.9 2.6 -1.3 2.6 2.4 2.0
Arm fat-free mass (right) 0.3 1.3 2.8 -0.4 1.0 1.7 1.5 -0.4 0.6 1.7 1.0
Exposure to tobacco smoke outside home 0.6 0.8 1.8 -0.9 1.1 0.0 0.4 -1.3 -0.5 1.2 0.7
Comparative body size at age 10 3.9 10.7 20.5 -2.3 4.5 3.1 3.9 -2.9 2.1 3.6 3.0
Number of full brothers 1.4 1.8 3.4 -1.1 1.2 1.2 1.1 -1.8 1.7 1.0 1.3
Worry too long after embarrassment 0.6 1.0 2.3 -1.5 1.2 -0.2 -1.4 1.0 -0.1 0.7 0.7
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.6 1.8 -0.1 -0.2 -1.1 -0.5 0.9 -1.3 0.6 0.4
Wheeze or whistling in the chest in last year 0.4 0.7 1.8 0.7 0.1 1.3 -0.1 0.9 -1.1 0.8 0.6
Number of children fathered 0.7 0.8 1.8 -1.1 1.3 1.2 -0.1 -0.8 1.0 0.3 0.8
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.5 1.6 -0.4 0.9 0.5 -0.4 1.3 0.1 0.9 0.4
Age at first live birth 1.5 2.7 5.7 2.0 -1.7 -2.3 0.2 0.8 -0.3 -2.4 -1.8
Pulse wave peak to peak time 0.2 0.2 0.5 0.7 -0.3 -0.6 0.7 -0.0 0.5 -0.3 0.5
Health satisfaction 0.3 0.4 1.2 0.5 -0.4 -0.9 -0.0 0.1 1.1 -0.7 -0.5
Shortness of breath walking on level ground 0.2 0.3 0.5 -0.7 0.4 0.6 0.4 -0.4 0.7 0.5 0.2
Qualifications: College or University degree 0.6 1.9 4.0 0.5 -2.0 -1.7 -1.5 1.6 -0.9 -0.7 -1.2
Eye problems/disorders: None of the above 1.0 1.2 3.9 0.5 -0.9 -0.5 -1.0 0.5 -1.5 -0.7 -2.0
Mouth/teeth dental problems: Loose teeth 0.9 1.1 3.6 0.1 -0.4 -1.0 -0.8 1.9 -0.6 -1.1 -1.4
Emphysema/chronic bronchitis 0.6 0.7 2.7 1.7 -0.9 -0.3 -0.5 0.8 -0.8 -0.7 -0.2
Medication for pain relief, constipation, heartburn 1.1 1.8 2.9 1.1 -1.7 -1.2 -1.5 1.2 -1.7 -0.9 -1.3
Neck or shoulder pain in last month 0.1 0.2 0.5 0.1 0.5 0.2 0.7 0.1 0.7 -0.0 0.3
Medication: Blood pressure 0.7 1.3 6.9 0.1 1.3 0.1 0.5 -0.2 1.0 0.5 2.6
Angina (self-reported) 0.4 0.5 2.5 -0.0 0.8 0.7 0.1 0.5 1.6 -0.2 0.2
Migraine (self-reported) 0.9 1.2 2.5 -1.6 1.5 1.0 -0.1 0.4 -0.9 1.4 0.8
Medication: Ibuprofen 0.6 0.7 2.7 -0.6 -0.3 0.3 0.4 0.1 -1.2 1.6 0.8
Medication: Allopurinol 4.2 5.6 9.5 -2.1 3.1 2.1 2.0 -2.3 1.3 2.8 2.7
Medication: Omeprazole 3.1 3.7 5.7 -0.8 2.3 2.1 2.4 -2.1 1.7 1.4 2.1
Medication: Seretide 50 evohaler 3.4 3.9 6.8 -1.9 1.8 2.6 1.9 -1.9 0.8 2.4 1.8
Mean time to correctly identify matches 0.9 1.8 3.4 -0.1 1.8 1.1 1.8 -0.8 1.2 1.8 1.1
Heart disease (mother) 0.3 0.4 1.3 0.3 0.4 -0.3 0.7 -0.8 0.0 0.5 1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 2.2 2.6 5.7 -1.5 1.2 2.4 1.7 -1.4 1.1 1.9 1.4
Whole body fat mass 1.2 4.8 8.9 -2.2 3.0 2.8 2.0 -0.8 1.5 2.8 1.3
Leg fat mass (right) 1.8 7.2 12.7 -2.1 3.6 3.2 2.9 -1.5 2.2 3.1 2.2
Arm predicted mass (right) 0.3 1.5 3.1 -0.4 1.0 1.6 1.6 -0.6 0.7 1.8 1.2
Pulse rate, automated reading 0.3 1.0 5.3 -0.2 0.5 -0.3 -2.3 0.9 -1.1 -0.3 -0.6
Alcohol intake frequency. 0.4 0.9 1.5 -1.1 1.2 1.1 0.8 -0.8 0.6 0.9 1.2
Comparative height size at age 10 0.3 1.7 6.7 -0.5 -1.0 -0.5 -2.6 1.0 -1.3 -0.7 -1.5
Number of full sisters 0.6 0.7 2.6 -0.1 1.6 -0.1 1.2 -0.4 0.7 0.2 0.8
Suffer from ‘nerves’ 1.0 1.6 5.7 2.4 -1.2 -1.2 -0.3 -0.4 -0.2 -1.9 -0.8
Overall health rating 0.4 0.8 1.9 -0.5 1.4 0.2 0.4 -0.3 -0.9 1.2 1.2
Chest pain or discomfort 0.3 0.4 1.3 1.1 0.1 0.1 0.7 0.1 1.1 -0.2 0.7
Had major operations 1.4 1.7 4.7 -1.1 1.0 1.7 0.7 0.6 2.2 0.7 1.5
Age at last live birth 0.2 0.2 0.6 -0.1 -0.4 -0.6 0.8 -0.4 -0.5 -0.6 0.2
Family relationship satisfaction 0.4 0.5 1.3 -1.0 -0.1 -0.4 -1.0 1.1 -0.4 0.5 0.0
Leg pain on walking 0.8 1.0 2.2 -1.0 1.0 0.7 0.4 -1.1 1.5 1.4 0.7
Qualifications: NVQ or HND or HNC or equivalent 2.6 3.1 6.6 -1.6 2.4 1.8 1.2 -1.0 0.0 2.6 2.0
Commuting to job workplace: Car/motor vehicle 0.7 0.8 2.4 -0.8 0.7 0.9 1.3 0.1 -0.0 1.6 0.7
Illness, injury, bereavement, stress in last 2 years 1.2 1.4 3.1 0.6 -1.6 -0.9 -1.8 0.9 -0.3 -1.2 -1.4
Medication: Aspirin 0.1 0.1 0.5 0.4 0.4 -0.1 -0.0 0.1 0.5 -0.7 0.2
Supplements: Vitamin C 0.3 0.4 0.9 0.9 -0.9 -1.0 -0.7 0.1 -0.0 -0.6 -0.2
Knee pain experienced in last month 0.5 0.8 2.3 0.8 -1.0 -0.2 0.4 -0.9 -1.5 0.6 -0.9
Hypertension (Self-reported) 1.6 4.5 12.0 -1.0 2.7 1.9 2.3 -1.1 1.5 1.9 3.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.9 2.2 4.7 0.2 1.3 1.7 1.6 -2.2 0.8 1.4 1.8
Illnesses of father: Heart disease 0.1 0.2 0.3 -0.5 -0.5 -0.5 0.0 -0.6 0.0 -0.4 -0.3
Illnesses of siblings: Diabetes 3.1 3.8 4.6 -1.8 2.1 2.1 1.7 -2.1 1.5 2.2 2.0
Smoking status: Previous 0.5 0.8 3.0 -0.2 -0.2 -0.4 -1.7 1.1 -0.7 0.1 -1.1
Forced expiratory volume in 1-second (FEV1), predicted 0.5 1.0 4.0 -0.0 -0.5 -0.4 -0.9 1.6 -2.0 -0.5 -0.7
Whole body fat-free mass 0.4 2.2 5.6 -1.3 1.4 2.0 1.5 -0.2 0.3 2.4 1.4
Leg fat-free mass (right) 0.8 4.1 8.8 -1.7 2.5 2.5 2.1 -1.1 0.9 3.0 1.7
Arm fat percentage (left) 2.3 9.2 18.7 -2.9 4.3 3.6 2.6 -1.7 2.5 3.6 2.1
Average weekly red wine intake 0.3 0.4 1.2 0.8 -0.3 -0.5 1.1 0.3 0.9 -0.3 0.1
Handedness (chirality/laterality): Left-handed 0.6 0.7 2.0 -0.4 -0.2 0.3 1.2 -1.0 0.8 0.4 1.4
Mood swings 0.3 0.5 1.6 1.3 -0.4 -0.6 -0.2 0.5 0.2 -1.0 -0.4
Loneliness, isolation 1.6 2.1 4.0 0.8 -1.5 -1.4 -1.6 2.0 -1.7 -0.7 -1.6
Long-standing illness, disability or infirmity 0.5 0.7 1.6 0.1 0.7 1.3 -0.1 0.7 0.5 1.1 1.3
Ever had bowel cancer screening 0.3 0.3 0.6 -0.5 0.5 0.8 0.0 -0.7 0.7 0.1 0.5
Diabetes diagnosed by doctor 0.6 0.9 3.2 -0.7 1.8 1.0 0.4 1.0 0.4 1.2 0.4
Ever had stillbirth, spontaneous miscarriage or termination 1.0 1.0 3.7 -0.4 -0.5 -0.9 -1.9 1.6 -0.9 -0.5 0.0
Friendships satisfaction 0.3 0.4 1.0 -0.6 -0.4 -1.0 -0.7 0.4 -1.0 -0.1 -0.1
Qualifications: nursing, teaching 1.4 2.1 6.6 -0.6 -1.6 -0.6 -1.7 1.6 -2.6 -0.4 -1.3
Commuting to job workplace: Walk 1.1 1.2 4.3 -1.6 0.6 0.4 1.2 -2.1 0.2 0.9 -0.0
Eye problems/disorders: Cataract 0.1 0.2 0.7 0.4 -0.3 -0.1 0.2 -0.0 0.8 -0.2 0.4
Mouth/teeth dental problems: Mouth ulcers 1.4 2.2 5.1 -0.9 -1.5 -1.1 -2.3 1.3 -2.0 -0.7 -1.4
Medication for cholesterol 0.4 0.7 2.2 0.1 -1.5 -0.2 -1.0 0.5 -0.4 -0.5 -1.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.4 2.8 4.8 -1.2 1.8 0.7 2.2 -1.9 1.7 1.9 1.6
Back pain experienced in last month 0.3 0.5 2.5 -0.4 0.2 -0.4 -0.1 0.3 -1.6 1.0 0.4
Mineral and other dietary supplements 1.8 2.4 5.8 2.4 -1.5 -1.7 -0.3 1.2 -1.2 -2.0 -0.9
Breast cancer (self-reported) 0.5 0.5 1.4 -0.5 0.4 0.7 0.7 -1.1 -0.3 1.2 -0.6
Asthma (self-reported) 1.2 2.4 5.4 -1.6 1.8 2.1 0.9 -0.1 0.1 2.3 1.6
Osteoporosis (self-reported) 0.1 0.2 0.7 0.2 -0.5 -0.0 -0.5 0.2 0.2 -0.8 -0.3
Osteoarthritis (self-reported) 1.4 1.8 4.0 -1.5 1.6 1.7 1.2 -0.8 -0.1 2.0 0.7
Medication: Aspirin 0.1 0.1 0.4 0.3 0.5 -0.1 -0.2 0.6 0.2 -0.6 0.2
Medication: Gliclazide 2.6 3.0 6.2 -1.9 2.4 2.5 1.4 -1.0 1.2 1.9 0.7
Illnesses of father: None of the above (group 1) 0.3 0.4 0.7 -0.8 0.8 0.6 0.8 0.1 0.9 -0.1 0.3
Smoking status: Current 2.6 4.2 6.6 2.0 -1.5 -1.1 -2.6 2.5 -1.8 -2.4 -2.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.2 0.7 0.1 -0.2 0.2 -0.5 0.4 0.8 -0.2 -0.1
Whole body water mass 0.4 2.5 6.3 -1.3 1.6 2.1 1.6 -0.3 0.4 2.5 1.5
Leg predicted mass (right) 0.7 4.0 8.5 -1.7 2.4 2.4 2.1 -1.1 0.8 2.9 1.7
Arm fat mass (left) 2.0 8.1 16.1 -2.6 4.0 3.6 2.5 -1.3 2.1 3.6 1.9
Number of self-reported non-cancer illnesses 0.9 1.6 5.8 0.0 1.8 1.1 0.8 -0.2 0.5 1.5 2.4
Average weekly champagne plus white wine intake 0.6 0.9 3.9 -0.1 -1.2 -0.7 -0.3 2.0 -1.0 -0.2 -0.1
Miserableness 0.1 0.1 0.4 -0.0 0.1 0.2 -0.0 -0.3 -0.5 0.6 0.1
Guilty feelings 1.0 1.6 3.6 -1.9 1.8 0.9 0.7 -0.9 1.1 1.2 1.0
Wears glasses or contact lenses 0.5 0.6 2.5 0.7 -0.5 0.2 -0.1 1.6 -0.6 0.3 -0.9
Ever taken oral contraceptive pill 0.8 0.9 2.2 1.2 -0.7 -1.1 -0.8 0.7 -0.5 -0.9 -1.5
Hearing aid user 1.0 1.1 3.0 -0.5 0.7 1.5 1.5 -0.4 0.1 1.7 0.5
Mother’s age at death 0.9 1.1 3.9 -0.2 0.7 0.6 2.0 -1.4 1.2 0.8 0.5
Financial situation satisfaction 1.7 2.2 4.4 -0.1 -1.7 -1.0 -1.8 2.1 -1.3 -1.4 -1.5
Tinnitus: Yes, now most or all of the time 0.3 0.4 1.0 0.3 0.4 0.3 -0.6 1.0 -1.0 -0.3 -0.4
Commuting to job workplace: Public transport 1.4 1.6 4.4 0.8 -1.8 -1.4 -1.4 0.3 0.2 -2.1 -0.8
Eye problems/disorders: Glaucoma 1.6 1.9 3.9 0.1 1.9 1.5 1.5 -1.4 2.0 0.0 1.1
Medication: Blood pressure 0.4 0.8 2.8 0.7 0.9 0.2 1.7 -0.9 0.5 0.2 1.1
Pain type(s) experienced in last month: Hip pain 0.6 0.8 2.0 -1.4 0.7 1.2 0.1 0.6 -0.3 1.1 0.9
Supplements: Fish oil (including cod liver oil) 2.0 2.6 8.0 -2.8 1.6 2.0 -0.1 0.0 1.0 2.0 0.8
High cholesterol (Self-reported) 0.4 0.7 2.6 -0.2 1.1 0.2 -0.3 -0.3 1.2 -0.3 1.6
Medication: Bendroflumethiazide 0.4 0.6 2.0 1.4 0.0 -1.0 -0.1 -0.1 0.1 -1.3 -0.0
Medication: Paracetamol 0.1 0.1 0.7 0.8 0.5 0.0 -0.1 0.1 0.4 -0.1 0.2
Medication: Lisinopril 0.6 0.8 2.7 0.1 0.8 0.9 1.6 -0.8 -0.3 0.5 1.0
Medication: Atorvastatin 0.1 0.1 0.7 -0.2 0.2 -0.2 -0.0 -0.3 0.2 -0.1 0.9
Illnesses of father: High blood pressure 0.9 1.1 3.1 1.3 -0.3 -1.1 -1.0 1.8 -0.9 -0.8 -0.4
Alcohol drinker status: Never 4.0 4.8 7.6 -0.7 1.6 2.6 2.8 -1.6 2.5 2.2 2.8
Ever smoked 2.3 4.0 8.6 1.8 -1.8 -1.8 -2.9 1.9 -1.0 -2.0 -2.2
Basal metabolic rate 0.5 2.7 6.5 -1.5 1.9 2.2 1.6 -0.4 0.5 2.5 1.4
Leg fat percentage (left) 1.5 5.3 8.6 -1.3 2.9 2.8 2.6 -1.4 2.7 2.2 1.8
Arm fat-free mass (left) 0.4 1.8 5.0 -1.0 1.3 1.9 1.3 -0.2 0.3 2.2 1.2
Number of operations (self-reported) 1.0 1.4 4.3 -2.1 1.4 1.4 0.1 0.1 0.8 1.4 0.8
Average weekly beer plus cider intake 2.8 4.1 6.9 1.7 -2.0 -2.6 -2.1 1.6 -2.1 -2.3 -1.6
Irritability 1.2 2.0 4.8 0.8 -1.0 -1.4 -1.7 2.2 -1.8 -1.1 -0.6
Risk taking 0.3 0.5 1.4 -1.2 1.0 0.5 -0.4 0.4 0.7 0.5 0.3
Ever had prostate specific antigen (PSA) test 0.1 0.2 0.3 -0.3 -0.5 -0.4 -0.0 0.5 0.4 -0.5 0.4
Fractured/broken bones in last 5 years 0.0 0.0 0.1 -0.0 0.3 0.2 -0.0 0.1 0.1 0.1 -0.3
Age started oral contraceptive pill 1.9 2.4 4.4 -2.0 1.5 1.8 0.8 -0.5 1.4 2.1 1.6
Diastolic blood pressure, automated reading 0.8 2.5 9.4 -0.1 2.0 1.4 0.9 -0.0 0.6 1.8 3.1
Ever depressed for a whole week 0.5 0.6 1.3 -0.1 -1.2 -1.0 -0.9 0.3 -0.7 -0.3 -0.9
Unable to work because of sickness or disability 0.3 0.4 1.5 -0.4 1.2 -0.4 0.3 -0.5 0.2 0.5 1.0
Commuting to job workplace: Cycle 0.8 1.0 2.9 -0.3 -0.5 -0.7 -1.6 1.7 -1.2 -0.4 -0.6
Myopia 0.7 1.1 3.0 -1.5 0.4 -0.1 -1.3 0.4 -1.7 0.9 0.6
Vascular/heart problems diagnosed by doctor 2.0 5.5 12.3 1.1 -2.9 -2.2 -2.7 1.4 -2.1 -2.0 -3.5
Cholesterol lowering medication 0.1 0.1 0.9 -0.2 0.9 0.2 -0.1 -0.2 0.0 0.1 -0.1
Medication: Omeprazole (e.g. Zanprol) 6.1 7.4 13.7 -0.8 2.9 2.6 3.7 -3.5 2.5 2.2 2.6
Pain experienced in last month 0.3 0.4 1.4 -0.5 1.1 0.7 -0.0 0.2 1.2 -0.1 0.3
Supplements: Calcium 0.6 0.6 2.7 -1.7 0.3 0.1 -0.8 0.8 -0.3 0.8 0.5
Basal cell carcinoma (self-reported) 0.4 0.5 1.5 1.0 0.4 -0.3 -0.6 -0.3 -1.2 -0.7 0.1
Heart attack/myocardial infarction (self-reported) 0.7 0.9 2.4 0.8 -0.8 -1.0 -1.3 1.6 0.2 -1.1 -0.1
Deep venous thrombosis (DVT) (self-reported) 1.1 1.4 3.1 -1.3 1.3 1.7 0.9 -0.1 -0.6 1.8 0.6
Heart disease (siblings) 2.2 2.7 5.6 -0.1 1.5 0.6 1.6 -2.3 2.4 1.1 2.1
Alcohol drinker status: Previous 1.5 1.7 4.1 -0.6 -0.5 -0.8 -1.9 2.0 -1.8 -0.4 -1.0
Pack years of smoking 1.5 2.2 4.3 2.1 -1.6 -1.6 -0.4 1.1 -1.5 -1.5 -1.4
Impedance of whole body 3.4 17.5 23.7 2.2 -4.4 -4.7 -4.8 3.5 -3.5 -4.9 -4.7
Leg fat mass (left) 1.8 7.0 12.0 -1.8 3.5 3.2 3.0 -1.6 2.3 3.0 2.1
Arm predicted mass (left) 0.3 1.5 4.2 -0.7 1.1 1.8 1.3 -0.2 0.2 2.0 1.2