TWAS hub - UBE2R2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0490	0.0250	1.8e-03	0.016	0.014	0.003	0.012	0.005	3.6e-03	7.5e-03	1.3e-01	1.1e-02	6.6e-02
2	GTEx	Cells Transformed fibroblasts	0.1450	0.0420	3.6e-06	0.052	NA	0.154	NA	0.139	9.0e-05	NA	1.2e-11	NA	1.4e-10
3	METSIM	Adipose	0.0336	0.0163	4.0e-03	0.003	0.000	-0.002	0.003	-0.002	1.1e-01	3.3e-01	8.4e-01	9.6e-02	7.6e-01
4	ROSMAP	Brain Pre-frontal Cortex	0.2157	0.0406	0.0e+00	0.199	0.192	0.205	0.210	0.203	5.4e-25	4.1e-24	7.2e-26	1.9e-26	1.3e-25
5	YFS	Blood	0.0150	0.0071	3.8e-03	0.007	0.004	0.005	0.004	0.006	1.6e-03	1.5e-02	6.0e-03	1.0e-02	2.6e-03
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.0956	0.0756	1.9e-03	0.001	0.000	0.018	NA	0.004	2.4e-01	3.6e-01	4.0e-03	NA	9.9e-02
7	TCGA	Prostate Adenocarcinoma	0.0429	0.0233	4.7e-04	0.008	0.024	0.019	NA	0.008	4.8e-02	1.3e-03	3.9e-03	NA	4.0e-02
8	TCGA	Thyroid Carcinoma	0.0670	0.0320	5.6e-05	0.027	0.051	0.032	NA	0.039	1.0e-03	9.2e-06	3.9e-04	NA	9.9e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Body Mass Index (BMI) (2010)	7.9	10.8	17.3	-1.6	3.4	3.5	4.2	-3.8	2.6	3.5	3.0
Type 2 Diabetes (T2D) (2012)	6.6	7.6	14.5	-3.8	2.7	2.4	1.9	-3.1	1.9	3.3	2.3
Medication: Omeprazole (e.g. Zanprol)	6.1	7.4	13.7	-0.8	2.9	2.6	3.7	-3.5	2.5	2.2	2.6
Prostate Cancer	5.8	8.2	11.6	3.4	-3.4	-3.2	-2.1	1.2	-2.4	-3.3	-3.2
Hair/balding pattern: Pattern 3	5.7	8.5	15.6	3.3	-3.1	-3.2	-1.7	2.1	-2.6	-2.7	-4.0
Triglycerides	5.5	9.0	13.8	-3.0	2.7	2.2	3.3	-3.5	2.2	3.0	3.7
BMI	4.5	26.2	38.3	-3.7	6.2	6.0	6.0	-3.4	4.6	5.6	4.5
Medication: Allopurinol	4.2	5.6	9.5	-2.1	3.1	2.1	2.0	-2.3	1.3	2.8	2.7
Hand grip strength (right)	4.1	11.2	14.3	3.6	-3.8	-3.8	-3.2	3.4	-2.9	-3.5	-2.4
Alcohol drinker status: Never	4.0	4.8	7.6	-0.7	1.6	2.6	2.8	-1.6	2.5	2.2	2.8
Impedance of leg (left)	3.9	19.0	29.7	3.3	-5.1	-4.9	-4.5	3.5	-3.3	-5.5	-4.3
Comparative body size at age 10	3.9	10.7	20.5	-2.3	4.5	3.1	3.9	-2.9	2.1	3.6	3.0
Hand grip strength (left)	3.5	9.3	13.5	3.6	-3.7	-3.2	-3.0	2.9	-1.9	-3.5	-1.9
Impedance of leg (right)	3.4	16.4	23.7	2.7	-4.7	-4.7	-4.3	3.5	-3.3	-4.9	-3.8
Medication: Seretide 50 evohaler	3.4	3.9	6.8	-1.9	1.8	2.6	1.9	-1.9	0.8	2.4	1.8
Impedance of whole body	3.4	17.5	23.7	2.2	-4.4	-4.7	-4.8	3.5	-3.5	-4.9	-4.7
Supplements: Glucosamine	3.3	4.3	9.8	-0.6	1.2	1.7	2.6	-3.1	3.0	1.5	1.3
Lung FEV1/FVC ratio	3.1	15.7	29.8	-2.5	4.0	3.1	4.9	-5.2	5.5	2.5	2.7
Forced vital capacity (FVC)	3.1	11.9	22.5	1.1	-3.2	-3.0	-4.6	4.7	-4.2	-2.4	-2.7
Fluid intelligence score	3.1	6.4	9.2	1.3	-2.9	-2.1	-3.0	2.8	-1.8	-3.0	-2.8
Medication: Omeprazole	3.1	3.7	5.7	-0.8	2.3	2.1	2.4	-2.1	1.7	1.4	2.1
Illnesses of siblings: Diabetes	3.1	3.8	4.6	-1.8	2.1	2.1	1.7	-2.1	1.5	2.2	2.0
Gout (self-reported)	3.0	4.1	7.6	-2.2	2.6	1.5	1.8	-1.7	1.1	2.8	2.2
Body mass index (BMI)	2.9	12.4	20.7	-2.5	4.5	4.2	3.7	-2.4	3.1	4.1	2.9
Hair/balding pattern: Pattern 2	2.9	3.7	7.9	-1.4	2.1	1.9	1.9	-1.3	1.5	2.0	2.8
Smoking Status	2.8	6.7	12.9	2.1	-2.2	-1.7	-3.6	2.6	-2.4	-2.5	-3.1
Chronotype (morning person)	2.8	6.4	11.8	-1.6	3.4	2.2	3.1	-2.5	2.1	2.4	2.4
Average weekly beer plus cider intake	2.8	4.1	6.9	1.7	-2.0	-2.6	-2.1	1.6	-2.1	-2.3	-1.6
Forced vital capacity (FVC), Best measure	2.7	9.8	19.2	0.7	-2.5	-2.6	-4.3	4.0	-4.4	-2.0	-2.6
Ovarian Cancer	2.6	3.4	6.2	-2.2	2.4	2.1	0.6	0.2	0.3	2.5	2.3
Hair/balding pattern: Pattern 4	2.6	6.2	10.5	-2.3	2.7	2.4	1.9	-2.0	2.7	2.5	3.2
Qualifications: NVQ or HND or HNC or equivalent	2.6	3.1	6.6	-1.6	2.4	1.8	1.2	-1.0	0.0	2.6	2.0
Medication: Gliclazide	2.6	3.0	6.2	-1.9	2.4	2.5	1.4	-1.0	1.2	1.9	0.7
Smoking status: Current	2.6	4.2	6.6	2.0	-1.5	-1.1	-2.6	2.5	-1.8	-2.4	-2.1
Number of live births	2.5	3.5	5.6	-1.0	2.4	1.9	2.1	-1.7	1.3	1.8	2.3
Mean Putamen Volume	2.4	2.8	4.5	1.5	-1.3	-1.9	-1.5	2.1	-1.9	-1.4	-1.5
Systolic blood pressure, automated reading	2.4	7.1	14.6	-0.1	2.8	2.3	3.4	-2.6	2.8	1.7	3.8
Impedance of arm (left)	2.4	11.2	18.7	1.0	-3.0	-3.8	-4.3	3.0	-2.8	-3.7	-4.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.4	2.8	4.8	-1.2	1.8	0.7	2.2	-1.9	1.7	1.9	1.6
Arm fat percentage (right)	2.3	9.1	17.6	-3.2	4.2	3.7	2.4	-1.4	2.3	3.8	2.0
Prospective memory result	2.3	2.8	5.4	0.4	1.6	1.0	2.3	-2.3	1.6	1.4	1.8
Arm fat percentage (left)	2.3	9.2	18.7	-2.9	4.3	3.6	2.6	-1.7	2.5	3.6	2.1
Ever smoked	2.3	4.0	8.6	1.8	-1.8	-1.8	-2.9	1.9	-1.0	-2.0	-2.2
Multivitamins +/- minerals	2.2	2.9	12.4	-3.5	0.7	1.0	-0.0	0.0	-1.1	2.6	0.9
Impedance of arm (right)	2.2	10.1	18.2	0.2	-2.8	-3.5	-4.3	3.4	-3.1	-2.9	-3.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.2	2.6	5.7	-1.5	1.2	2.4	1.7	-1.4	1.1	1.9	1.4
Heart disease (siblings)	2.2	2.7	5.6	-0.1	1.5	0.6	1.6	-2.3	2.4	1.1	2.1
High blood pressure	2.1	5.8	13.4	-1.0	3.0	2.2	2.7	-1.5	2.0	2.1	3.7
Ever unenthusiastic/disinterested for a whole week	2.1	2.6	4.9	1.5	-2.2	-2.2	-1.5	0.8	-0.4	-2.0	-1.4
Mouth/teeth dental problems: Bleeding gums	2.1	2.7	5.9	1.5	-2.4	-2.2	-1.5	0.2	-1.0	-2.0	-1.2
Glaucoma (self-reported)	2.1	2.5	5.1	-0.6	2.3	1.5	1.5	-1.9	2.2	0.0	1.2
Verbal and Numeric Reasoning (VNR)	2.0	4.7	6.9	0.4	-2.5	-2.1	-2.6	1.8	-1.9	-2.6	-2.6
Waist circumference	2.0	7.5	15.4	-2.7	3.9	3.4	2.3	-1.0	0.8	3.9	1.9
Arm fat mass (left)	2.0	8.1	16.1	-2.6	4.0	3.6	2.5	-1.3	2.1	3.6	1.9
Supplements: Fish oil (including cod liver oil)	2.0	2.6	8.0	-2.8	1.6	2.0	-0.1	0.0	1.0	2.0	0.8
Vascular/heart problems diagnosed by doctor	2.0	5.5	12.3	1.1	-2.9	-2.2	-2.7	1.4	-2.1	-2.0	-3.5
Intelligence (Savage-Jansen 2018)	1.9	5.9	9.3	0.1	-2.6	-2.5	-3.0	2.5	-2.4	-2.6	-2.5
Arm fat mass (right)	1.9	7.7	15.2	-2.6	3.9	3.5	2.4	-1.3	2.0	3.5	1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.9	2.2	4.7	0.2	1.3	1.7	1.6	-2.2	0.8	1.4	1.8
Age started oral contraceptive pill	1.9	2.4	4.4	-2.0	1.5	1.8	0.8	-0.5	1.4	2.1	1.6
Bipolar Disorder (2018)	1.8	2.8	5.0	-2.1	1.9	1.3	-0.8	1.2	-1.3	2.0	2.2
Vitamin and mineral supplements	1.8	2.5	5.8	2.3	0.7	0.4	2.0	-1.5	2.4	-1.4	0.3
Current tobacco smoking	1.8	3.0	5.3	1.8	-1.3	-0.9	-2.1	1.9	-1.3	-2.3	-1.7
Mouth/teeth dental problems: Dentures	1.8	3.0	5.5	-1.2	2.1	2.3	1.8	-1.0	0.7	2.3	1.5
Leg fat mass (right)	1.8	7.2	12.7	-2.1	3.6	3.2	2.9	-1.5	2.2	3.1	2.2
Mineral and other dietary supplements	1.8	2.4	5.8	2.4	-1.5	-1.7	-0.3	1.2	-1.2	-2.0	-0.9
Leg fat mass (left)	1.8	7.0	12.0	-1.8	3.5	3.2	3.0	-1.6	2.3	3.0	2.1
Had menopause	1.7	2.2	3.7	-1.3	1.3	1.2	1.8	-1.3	1.6	1.9	1.2
Birth weight	1.7	3.6	6.7	2.5	-2.4	-1.5	-1.0	1.7	-0.5	-2.0	-2.6
Financial situation satisfaction	1.7	2.2	4.4	-0.1	-1.7	-1.0	-1.8	2.1	-1.3	-1.4	-1.5
Time employed in main current job	1.6	1.8	3.6	0.5	-1.9	-1.9	-1.7	0.7	-0.3	-1.7	-0.8
Leg fat percentage (right)	1.6	5.8	9.6	-1.8	3.1	2.9	2.6	-1.3	2.6	2.4	2.0
Hypertension (Self-reported)	1.6	4.5	12.0	-1.0	2.7	1.9	2.3	-1.1	1.5	1.9	3.5
Loneliness, isolation	1.6	2.1	4.0	0.8	-1.5	-1.4	-1.6	2.0	-1.7	-0.7	-1.6
Eye problems/disorders: Glaucoma	1.6	1.9	3.9	0.1	1.9	1.5	1.5	-1.4	2.0	0.0	1.1
Pack years adult smoking proportion	1.5	2.3	4.8	2.2	-1.6	-1.6	-0.4	1.1	-1.5	-1.6	-1.4
Peak expiratory flow (PEF)	1.5	3.5	6.3	-0.5	-2.1	-2.2	-2.5	2.0	-2.5	-0.8	-0.9
Age at first live birth	1.5	2.7	5.7	2.0	-1.7	-2.3	0.2	0.8	-0.3	-2.4	-1.8
Leg fat percentage (left)	1.5	5.3	8.6	-1.3	2.9	2.8	2.6	-1.4	2.7	2.2	1.8
Alcohol drinker status: Previous	1.5	1.7	4.1	-0.6	-0.5	-0.8	-1.9	2.0	-1.8	-0.4	-1.0
Pack years of smoking	1.5	2.2	4.3	2.1	-1.6	-1.6	-0.4	1.1	-1.5	-1.5	-1.4
Age at First Birth	1.4	2.0	4.3	1.2	-1.4	-1.3	-1.5	0.8	-0.5	-2.1	-2.0
Blood White Count	1.4	10.7	20.1	-3.9	4.1	4.5	1.4	-1.4	1.5	4.0	3.4
Height	1.4	27.9	39.2	3.0	-5.5	-5.3	-6.2	6.3	-5.7	-4.8	-4.8
Respiratory disease	1.4	3.1	8.3	-1.1	2.0	2.1	0.9	0.5	-0.1	2.9	2.4
Number of treatments/medications taken	1.4	2.5	6.7	-0.9	2.0	1.6	0.6	-0.8	1.3	1.9	2.6
Ever used hormone-replacement therapy (HRT)	1.4	1.8	5.4	-2.3	1.1	1.3	0.2	-1.0	0.2	2.1	0.8
Diabetes (mother)	1.4	1.8	3.6	-1.6	1.5	1.9	1.1	0.1	0.4	1.7	1.1
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	3.2	-0.7	1.1	1.0	1.1	-1.6	0.1	1.6	1.8
Past tobacco smoking	1.4	2.6	7.3	-0.9	1.1	1.0	2.7	-2.0	1.4	0.8	1.9
Number of full brothers	1.4	1.8	3.4	-1.1	1.2	1.2	1.1	-1.8	1.7	1.0	1.3
Had major operations	1.4	1.7	4.7	-1.1	1.0	1.7	0.7	0.6	2.2	0.7	1.5
Qualifications: nursing, teaching	1.4	2.1	6.6	-0.6	-1.6	-0.6	-1.7	1.6	-2.6	-0.4	-1.3
Mouth/teeth dental problems: Mouth ulcers	1.4	2.2	5.1	-0.9	-1.5	-1.1	-2.3	1.3	-2.0	-0.7	-1.4
Osteoarthritis (self-reported)	1.4	1.8	4.0	-1.5	1.6	1.7	1.2	-0.8	-0.1	2.0	0.7
Commuting to job workplace: Public transport	1.4	1.6	4.4	0.8	-1.8	-1.4	-1.4	0.3	0.2	-2.1	-0.8
Bipolar Disorder (2011)	1.3	1.2	3.4	-1.2	1.3	1.0	-0.7	0.6	-0.3	1.2	1.9
HbA1C	1.3	1.5	4.3	-0.3	1.1	0.2	0.8	-2.1	1.1	1.0	1.8
Heel T-Score	1.3	10.5	24.2	-4.4	3.3	4.0	1.1	-3.3	0.1	4.9	1.2
Frequency of depressed mood in last 2 weeks	1.3	1.9	3.3	0.8	-0.9	-1.8	-1.8	1.6	-1.8	-0.8	-1.0
Other serious medical condition/disability diagnosed by doctor	1.3	1.6	3.6	-1.5	0.9	1.9	0.3	-0.1	0.4	1.6	1.9
Hayfever/allergic rhinitis (self-reported)	1.3	1.7	3.8	0.2	1.2	0.9	1.9	-1.8	1.3	1.1	1.1
Forced expiratory volume in 1-second (FEV1)	1.3	4.4	8.5	-0.1	-1.7	-2.1	-2.9	2.9	-2.6	-1.4	-1.5
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	5.0	0.1	-1.0	-1.1	-1.0	1.5	-2.2	-0.4	-1.2
Bipolar Disorder or Schizophrenia	1.2	2.8	8.1	-2.2	1.8	1.3	-0.7	0.8	-0.3	1.9	2.9
Blood Platelet Count	1.2	13.4	27.0	-1.7	4.7	3.7	5.2	-4.6	2.5	3.3	2.1
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.9	10.0	-3.2	1.7	1.8	0.2	-1.1	1.2	2.0	0.1
Qualifications: None of the above	1.2	2.6	6.0	0.3	1.6	0.5	2.2	-2.4	1.0	1.0	2.2
Falls in the last year	1.2	1.7	3.3	-1.4	1.1	1.2	1.7	-0.2	1.0	1.8	1.1
Happiness	1.2	1.4	3.8	1.3	-1.1	-1.9	-1.2	1.4	-0.8	-1.0	-0.3
Noisy workplace	1.2	1.5	2.7	-1.4	1.7	1.5	1.0	-1.0	0.8	1.2	1.0
Standing height	1.2	11.5	17.6	1.2	-3.9	-2.9	-4.0	4.2	-3.9	-2.7	-3.3
Qualifications: O levels/GCSEs or equivalent	1.2	1.9	5.2	0.3	-2.3	-0.8	-1.5	0.2	-0.2	-2.0	-1.7
Whole body fat mass	1.2	4.8	8.9	-2.2	3.0	2.8	2.0	-0.8	1.5	2.8	1.3
Illness, injury, bereavement, stress in last 2 years	1.2	1.4	3.1	0.6	-1.6	-0.9	-1.8	0.9	-0.3	-1.2	-1.4
Asthma (self-reported)	1.2	2.4	5.4	-1.6	1.8	2.1	0.9	-0.1	0.1	2.3	1.6
Irritability	1.2	2.0	4.8	0.8	-1.0	-1.4	-1.7	2.2	-1.8	-1.1	-0.6
HDL Cholesterol	1.1	1.9	3.6	0.4	-0.8	-1.0	-1.7	1.9	-1.1	-1.4	-1.8
Cardiovascular Disease	1.1	3.7	9.7	-0.5	2.2	1.5	2.5	-1.7	1.2	1.4	3.1
Medication: Co-codamol	1.1	1.2	2.4	0.5	1.5	0.7	1.6	-1.0	1.5	0.2	1.2
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	3.1	0.7	-1.3	-1.0	-1.5	1.8	-0.5	-0.4	-1.1
Hip circumference	1.1	4.9	9.3	-2.5	2.9	3.0	2.0	-1.0	1.6	2.6	0.9
Asthma	1.1	2.1	5.2	-1.6	1.7	2.0	0.7	0.1	-0.3	2.3	1.3
Medication for pain relief, constipation, heartburn	1.1	1.8	2.9	1.1	-1.7	-1.2	-1.5	1.2	-1.7	-0.9	-1.3
Commuting to job workplace: Walk	1.1	1.2	4.3	-1.6	0.6	0.4	1.2	-2.1	0.2	0.9	-0.0
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	3.1	-1.3	1.3	1.7	0.9	-0.1	-0.6	1.8	0.6
Schizophrenia vs Biploar Disorder	1.0	1.3	6.3	0.8	-0.3	0.2	0.3	-1.1	2.5	-1.5	0.1
Alzheimer’s Disease (in mother)	1.0	1.2	2.2	1.5	-1.4	-0.5	-0.9	0.7	-0.6	-1.5	-1.3
Blood Eosinophil Count	1.0	7.4	21.2	-4.6	1.5	3.2	1.9	-1.6	0.7	3.8	2.2
Lung FVC	1.0	5.0	15.1	0.7	-1.2	-2.0	-3.9	3.1	-2.4	-1.6	-1.2
Number of incorrect matches in round	1.0	1.7	5.0	-1.5	1.3	0.7	0.5	0.4	0.3	1.8	2.2
Pain all over the body in last month	1.0	1.1	4.4	2.1	-0.5	-1.3	-0.7	0.7	-0.3	-1.1	-0.1
Eye problems/disorders: None of the above	1.0	1.2	3.9	0.5	-0.9	-0.5	-1.0	0.5	-1.5	-0.7	-2.0
Suffer from ‘nerves’	1.0	1.6	5.7	2.4	-1.2	-1.2	-0.3	-0.4	-0.2	-1.9	-0.8
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.0	3.7	-0.4	-0.5	-0.9	-1.9	1.6	-0.9	-0.5	0.0
Guilty feelings	1.0	1.6	3.6	-1.9	1.8	0.9	0.7	-0.9	1.1	1.2	1.0
Hearing aid user	1.0	1.1	3.0	-0.5	0.7	1.5	1.5	-0.4	0.1	1.7	0.5
Number of operations (self-reported)	1.0	1.4	4.3	-2.1	1.4	1.4	0.1	0.1	0.8	1.4	0.8
Irritable Bowel Disease (IBD)	0.9	2.1	5.7	0.5	-1.1	-1.3	-2.0	2.4	0.1	-1.7	-1.0
Leg fat-free mass (left)	0.9	4.7	10.0	-2.0	2.7	2.5	2.2	-1.0	1.0	3.2	1.9
Maternal smoking around birth	0.9	1.3	6.1	0.1	-1.0	-0.8	-0.5	0.7	-2.5	-0.2	-1.3
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.1	7.7	-2.8	1.0	1.6	-0.3	-0.5	1.0	2.0	-0.3
Chronic bronchitis/emphysema (father)	0.9	1.0	2.9	1.1	-0.9	-0.7	-1.7	1.2	-1.1	-0.2	-0.0
Leg predicted mass (left)	0.9	4.6	9.8	-1.9	2.6	2.5	2.2	-0.9	0.9	3.1	1.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	2.7	6.1	0.1	-1.1	-1.6	-2.4	2.1	-2.5	-0.9	-1.1
Body fat percentage	0.9	3.7	7.7	-2.0	2.8	2.5	1.6	-0.6	1.8	2.2	0.8
Mouth/teeth dental problems: Loose teeth	0.9	1.1	3.6	0.1	-0.4	-1.0	-0.8	1.9	-0.6	-1.1	-1.4
Migraine (self-reported)	0.9	1.2	2.5	-1.6	1.5	1.0	-0.1	0.4	-0.9	1.4	0.8
Mean time to correctly identify matches	0.9	1.8	3.4	-0.1	1.8	1.1	1.8	-0.8	1.2	1.8	1.1
Number of self-reported non-cancer illnesses	0.9	1.6	5.8	0.0	1.8	1.1	0.8	-0.2	0.5	1.5	2.4
Mother’s age at death	0.9	1.1	3.9	-0.2	0.7	0.6	2.0	-1.4	1.2	0.8	0.5
Illnesses of father: High blood pressure	0.9	1.1	3.1	1.3	-0.3	-1.1	-1.0	1.8	-0.9	-0.8	-0.4
Coronary Artery Disease (CAD)	0.8	0.9	2.8	-0.7	0.7	1.0	0.9	-1.7	-0.0	1.1	0.8
Ulcerative Colitis	0.8	1.1	2.7	-0.2	-1.2	-0.2	-1.6	1.6	0.3	-1.4	-0.4
Type 2 Diabetes (T2D) (2018)	0.8	1.5	4.9	-1.1	1.6	1.2	0.7	0.9	-0.4	2.2	0.6
Supplements: Zinc	0.8	0.8	1.9	-1.1	0.8	1.1	0.7	-1.0	0.2	1.4	0.3
Medication: Metformin	0.8	1.1	3.1	-0.8	1.8	0.6	0.8	0.1	0.8	1.7	0.9
Diabetes (father)	0.8	0.9	2.3	0.3	1.1	0.4	1.5	-1.1	-0.6	1.4	0.0
Relative age voice broke	0.8	1.2	2.2	-0.9	0.1	1.4	1.5	-1.2	0.9	1.5	0.4
Trunk fat mass	0.8	3.6	7.6	-2.0	2.8	2.5	1.4	-0.2	1.5	2.3	0.9
Weight	0.8	3.8	7.0	-1.8	2.5	2.6	1.8	-0.5	1.2	2.6	1.3
Blood clot in the leg (DVT)	0.8	1.0	2.5	-1.3	1.1	1.4	0.5	-0.1	-0.9	1.6	0.4
Leg pain on walking	0.8	1.0	2.2	-1.0	1.0	0.7	0.4	-1.1	1.5	1.4	0.7
Leg fat-free mass (right)	0.8	4.1	8.8	-1.7	2.5	2.5	2.1	-1.1	0.9	3.0	1.7
Ever taken oral contraceptive pill	0.8	0.9	2.2	1.2	-0.7	-1.1	-0.8	0.7	-0.5	-0.9	-1.5
Diastolic blood pressure, automated reading	0.8	2.5	9.4	-0.1	2.0	1.4	0.9	-0.0	0.6	1.8	3.1
Commuting to job workplace: Cycle	0.8	1.0	2.9	-0.3	-0.5	-0.7	-1.6	1.7	-1.2	-0.4	-0.6
Depression (Nagel 2018)	0.7	1.0	2.2	0.7	-1.0	-1.4	-1.0	1.5	-1.2	-0.4	-0.0
Average weekly fortified wine intake	0.7	0.9	5.2	-2.3	-0.4	0.4	-0.4	-0.9	0.2	0.6	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	3.0	0.7	-0.5	-1.3	-0.2	1.2	-1.7	-0.2	-0.0
Sitting height	0.7	4.9	10.4	0.1	-2.2	-1.5	-2.9	3.2	-2.9	-1.7	-1.4
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.0	2.9	1.2	-0.4	-0.8	-1.0	1.7	-1.2	-0.4	-0.6
Hearing difficulty/problems with background noise	0.7	1.2	2.8	-1.6	1.7	1.1	-0.5	0.3	-0.2	1.2	1.1
Had other major operations	0.7	0.8	3.4	0.8	-0.2	-1.0	-0.5	0.4	-1.8	-0.0	-0.9
Allergy	0.7	1.5	3.1	0.4	-0.8	-1.3	-1.8	0.7	-0.8	-1.7	-1.6
Diabetes (self-reported)	0.7	1.2	3.9	-1.2	2.0	0.9	0.2	0.9	0.1	1.4	0.6
Father’s age at death	0.7	0.9	2.0	-1.2	0.5	1.0	1.0	1.1	0.2	1.4	0.6
Qualifications: A levels/AS levels or equivalent	0.7	1.5	4.3	0.4	-2.1	-1.1	-1.2	1.1	-1.0	-1.1	-1.4
Number of children fathered	0.7	0.8	1.8	-1.1	1.3	1.2	-0.1	-0.8	1.0	0.3	0.8
Medication: Blood pressure	0.7	1.3	6.9	0.1	1.3	0.1	0.5	-0.2	1.0	0.5	2.6
Commuting to job workplace: Car/motor vehicle	0.7	0.8	2.4	-0.8	0.7	0.9	1.3	0.1	-0.0	1.6	0.7
Leg predicted mass (right)	0.7	4.0	8.5	-1.7	2.4	2.4	2.1	-1.1	0.8	2.9	1.7
Myopia	0.7	1.1	3.0	-1.5	0.4	-0.1	-1.3	0.4	-1.7	0.9	0.6
Heart attack/myocardial infarction (self-reported)	0.7	0.9	2.4	0.8	-0.8	-1.0	-1.3	1.6	0.2	-1.1	-0.1
Ulcerative Colitis (UC)	0.6	1.2	2.7	0.4	-0.8	-0.9	-1.4	1.6	-0.3	-1.3	-1.1
Waist Hip Ratio (WHR)	0.6	2.5	9.6	-0.3	0.5	-0.6	-1.6	2.4	-3.1	1.2	-0.0
Sensitivity / hurt feelings	0.6	1.0	4.8	-0.4	1.3	0.0	-0.9	0.1	0.3	0.7	2.2
Medication for hormone replacement therapy	0.6	0.7	1.7	-0.6	1.2	0.7	0.3	0.2	0.5	0.9	1.3
Severe depression (siblings)	0.6	0.7	2.6	0.3	0.2	-0.9	-0.7	-0.7	1.6	-1.0	0.3
Trunk fat percentage	0.6	2.4	6.2	-1.7	2.5	2.0	0.8	-0.1	1.5	1.7	0.3
Fed-up feelings	0.6	1.0	1.7	0.9	-1.1	-0.8	-1.0	0.8	-1.3	-1.0	-1.0
Medication for cholesterol, blood pressure or diabetes	0.6	0.9	4.0	-0.6	-1.1	-0.1	-0.5	0.6	-1.2	0.2	-2.0
Medication: Amlodipine	0.6	0.8	2.3	0.7	0.7	0.5	1.1	-0.9	1.5	0.3	1.0
Exposure to tobacco smoke outside home	0.6	0.8	1.8	-0.9	1.1	0.0	0.4	-1.3	-0.5	1.2	0.7
Worry too long after embarrassment	0.6	1.0	2.3	-1.5	1.2	-0.2	-1.4	1.0	-0.1	0.7	0.7
Qualifications: College or University degree	0.6	1.9	4.0	0.5	-2.0	-1.7	-1.5	1.6	-0.9	-0.7	-1.2
Emphysema/chronic bronchitis	0.6	0.7	2.7	1.7	-0.9	-0.3	-0.5	0.8	-0.8	-0.7	-0.2
Medication: Ibuprofen	0.6	0.7	2.7	-0.6	-0.3	0.3	0.4	0.1	-1.2	1.6	0.8
Number of full sisters	0.6	0.7	2.6	-0.1	1.6	-0.1	1.2	-0.4	0.7	0.2	0.8
Handedness (chirality/laterality): Left-handed	0.6	0.7	2.0	-0.4	-0.2	0.3	1.2	-1.0	0.8	0.4	1.4
Diabetes diagnosed by doctor	0.6	0.9	3.2	-0.7	1.8	1.0	0.4	1.0	0.4	1.2	0.4
Average weekly champagne plus white wine intake	0.6	0.9	3.9	-0.1	-1.2	-0.7	-0.3	2.0	-1.0	-0.2	-0.1
Pain type(s) experienced in last month: Hip pain	0.6	0.8	2.0	-1.4	0.7	1.2	0.1	0.6	-0.3	1.1	0.9
Medication: Lisinopril	0.6	0.8	2.7	0.1	0.8	0.9	1.6	-0.8	-0.3	0.5	1.0
Supplements: Calcium	0.6	0.6	2.7	-1.7	0.3	0.1	-0.8	0.8	-0.3	0.8	0.5
Crohns Disease (2017)	0.5	1.2	3.2	0.6	-0.6	-0.9	-1.5	1.8	0.7	-1.3	-0.5
Systolic Blood Pressure	0.5	2.5	9.3	1.4	1.1	0.1	2.0	-1.4	0.9	0.1	3.0
Angina	0.5	0.6	3.6	0.0	0.8	0.7	0.3	0.3	1.9	-0.3	0.4
Heart attack	0.5	0.7	2.0	0.5	-0.7	-0.8	-1.1	1.4	0.2	-0.9	-0.0
Illnesses of siblings	0.5	0.7	1.6	-0.2	-0.8	-0.5	-0.2	1.0	-1.1	-0.6	-1.2
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.1	0.8	-0.5	-0.6	-0.5	1.5	-1.4	-0.5	-0.3
Medication: Cholesterol lowering	0.5	0.7	2.5	0.2	0.9	0.1	-0.1	-0.3	1.4	-0.5	1.6
Loud music exposure frequency	0.5	0.5	2.3	-0.2	0.3	0.4	0.5	0.3	-0.3	1.1	1.5
Knee pain experienced in last month	0.5	0.8	2.3	0.8	-1.0	-0.2	0.4	-0.9	-1.5	0.6	-0.9
Smoking status: Previous	0.5	0.8	3.0	-0.2	-0.2	-0.4	-1.7	1.1	-0.7	0.1	-1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	4.0	-0.0	-0.5	-0.4	-0.9	1.6	-2.0	-0.5	-0.7
Long-standing illness, disability or infirmity	0.5	0.7	1.6	0.1	0.7	1.3	-0.1	0.7	0.5	1.1	1.3
Breast cancer (self-reported)	0.5	0.5	1.4	-0.5	0.4	0.7	0.7	-1.1	-0.3	1.2	-0.6
Wears glasses or contact lenses	0.5	0.6	2.5	0.7	-0.5	0.2	-0.1	1.6	-0.6	0.3	-0.9
Basal metabolic rate	0.5	2.7	6.5	-1.5	1.9	2.2	1.6	-0.4	0.5	2.5	1.4
Ever depressed for a whole week	0.5	0.6	1.3	-0.1	-1.2	-1.0	-0.9	0.3	-0.7	-0.3	-0.9
Schizophrenia (2018)	0.4	0.9	3.5	-1.1	0.8	0.6	-0.3	0.1	0.7	0.8	1.9
LDL Cholesterol	0.4	0.6	1.8	0.2	-0.8	-0.9	-0.2	0.8	-1.4	-0.4	-0.7
Schizophrenia (2014)	0.4	0.8	2.4	-0.9	0.7	0.5	-1.2	0.8	0.1	0.4	1.6
Allergy or Eczema	0.4	1.0	2.7	0.2	0.4	0.5	1.6	-0.7	0.2	1.7	1.4
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	2.0	0.4	-0.4	-0.5	-0.6	1.4	-0.2	0.2	0.5
Age when periods started (menarche)	0.4	1.0	3.3	1.2	-0.7	-0.5	-0.3	1.8	-1.3	-0.3	-0.5
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.1	-0.6	0.5	1.0	0.3	-1.0	0.5	0.8	0.7
Medication: Atenolol	0.4	0.5	1.2	0.2	0.0	-0.6	-0.9	1.1	-0.5	-1.1	-0.5
High blood pressure (mother)	0.4	0.6	3.8	-0.2	-0.2	0.0	-0.9	2.0	-0.1	-0.3	0.3
Alcohol usually taken with meals	0.4	0.6	1.8	-0.2	-0.7	-0.7	-0.4	1.3	0.0	-0.9	-1.2
Nervous feelings	0.4	0.8	2.2	1.0	-0.9	-0.7	-1.5	0.7	0.5	-1.1	-0.0
Medication: Lansoprazole	0.4	0.4	1.3	1.1	0.4	0.9	0.9	-0.0	0.4	-0.2	0.0
Illnesses of mother	0.4	0.5	1.0	0.5	-0.9	-1.0	-0.6	-0.1	-0.5	-0.6	-1.0
Breastfed as a baby	0.4	0.6	1.3	-0.9	0.3	-0.5	-0.9	0.9	-1.1	-0.5	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	1.2	-0.8	0.2	-1.1	-0.8	0.0	-1.1	0.8	0.8
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	2.7	0.5	0.8	0.2	1.0	-0.3	-0.1	1.3	1.6
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.4	-0.7	-0.1	0.1	-1.1	1.2	-0.5	0.7	0.4
Chronic bronchitis/emphysema (mother)	0.4	0.5	1.1	1.1	0.3	-0.3	1.0	-1.0	0.4	-0.5	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	1.8	-0.1	-0.2	-1.1	-0.5	0.9	-1.3	0.6	0.4
Wheeze or whistling in the chest in last year	0.4	0.7	1.8	0.7	0.1	1.3	-0.1	0.9	-1.1	0.8	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	1.6	-0.4	0.9	0.5	-0.4	1.3	0.1	0.9	0.4
Angina (self-reported)	0.4	0.5	2.5	-0.0	0.8	0.7	0.1	0.5	1.6	-0.2	0.2
Alcohol intake frequency.	0.4	0.9	1.5	-1.1	1.2	1.1	0.8	-0.8	0.6	0.9	1.2
Overall health rating	0.4	0.8	1.9	-0.5	1.4	0.2	0.4	-0.3	-0.9	1.2	1.2
Family relationship satisfaction	0.4	0.5	1.3	-1.0	-0.1	-0.4	-1.0	1.1	-0.4	0.5	0.0
Whole body fat-free mass	0.4	2.2	5.6	-1.3	1.4	2.0	1.5	-0.2	0.3	2.4	1.4
Medication for cholesterol	0.4	0.7	2.2	0.1	-1.5	-0.2	-1.0	0.5	-0.4	-0.5	-1.2
Whole body water mass	0.4	2.5	6.3	-1.3	1.6	2.1	1.6	-0.3	0.4	2.5	1.5
Medication: Blood pressure	0.4	0.8	2.8	0.7	0.9	0.2	1.7	-0.9	0.5	0.2	1.1
High cholesterol (Self-reported)	0.4	0.7	2.6	-0.2	1.1	0.2	-0.3	-0.3	1.2	-0.3	1.6
Medication: Bendroflumethiazide	0.4	0.6	2.0	1.4	0.0	-1.0	-0.1	-0.1	0.1	-1.3	-0.0
Arm fat-free mass (left)	0.4	1.8	5.0	-1.0	1.3	1.9	1.3	-0.2	0.3	2.2	1.2
Basal cell carcinoma (self-reported)	0.4	0.5	1.5	1.0	0.4	-0.3	-0.6	-0.3	-1.2	-0.7	0.1
Alzheimer’s Disease (including proxy)	0.3	0.4	1.2	1.1	-0.7	0.3	-0.5	-0.0	-0.1	-0.9	-0.6
Breast Cancer	0.3	0.7	3.5	-0.3	0.0	-0.2	-0.3	1.9	-0.3	-1.2	-0.6
Crohns Disease (2012)	0.3	0.4	0.9	0.2	0.2	-0.5	-0.9	0.9	1.0	-0.8	0.3
Fasting Glucose	0.3	0.3	1.1	0.2	-0.6	0.6	0.3	-0.4	0.1	0.8	1.0
Lupus	0.3	0.4	1.3	-0.4	-0.0	1.1	-0.4	0.4	0.3	1.0	0.5
Blood Red Count	0.3	3.1	12.2	-3.5	0.7	2.1	-1.5	0.8	-0.8	1.5	1.4
Average weekly spirits intake	0.3	0.4	0.8	-0.0	0.8	0.9	0.9	-0.2	0.5	0.4	0.7
Relative age of first facial hair	0.3	0.7	3.6	0.5	-1.9	-0.3	-0.3	0.2	-0.4	-0.0	-1.1
Taking other prescription medications	0.3	0.5	1.4	0.8	0.1	1.0	-0.5	0.4	-0.1	0.8	1.2
Serious illness, injury or assault to yourself	0.3	0.3	0.8	-0.9	0.7	0.2	0.5	-0.5	0.7	0.4	0.2
Hayfever, allergic rhinitis or eczema	0.3	0.7	2.3	0.6	-0.5	-0.3	1.5	-1.0	0.2	0.9	0.7
Stomach or abdominal pain in last month	0.3	0.3	1.8	-0.1	-0.5	-0.5	0.1	-0.4	-1.3	-0.3	0.1
Medication: Levothyroxine sodium	0.3	0.5	2.0	0.5	0.6	-0.1	0.5	0.8	0.4	0.6	1.4
Medication: Ramipril	0.3	0.4	1.2	0.5	0.3	-0.4	-0.8	1.1	0.1	-0.7	-0.3
Neuroticism score	0.3	0.6	1.4	1.0	-0.5	-0.6	-1.2	1.2	-0.3	-0.7	-0.2
Pulse rate	0.3	0.5	2.8	0.2	0.2	-0.3	-1.7	0.5	-0.7	-0.1	-0.6
Lung cancer (father)	0.3	0.4	0.9	0.9	0.7	0.4	0.5	0.6	1.0	-0.3	0.3
Pulse wave Arterial Stiffness index	0.3	0.3	1.1	-0.5	-0.0	0.2	-1.0	0.4	-0.8	0.0	-0.7
Exposure to tobacco smoke at home	0.3	0.3	1.7	-0.1	0.6	0.3	-0.1	0.3	1.3	0.3	0.2
Tense / ‘highly strung’	0.3	0.5	1.3	0.4	1.0	0.3	0.6	-0.5	1.2	0.2	1.0
Pulse wave reflection index	0.3	0.4	1.2	-1.1	0.4	1.1	0.2	0.1	0.0	0.5	0.4
Headache pain in last month	0.3	0.5	1.2	-0.8	0.1	1.1	-0.2	-0.6	-1.0	0.7	0.5
High blood pressure (siblings)	0.3	0.4	1.4	0.8	-0.2	-0.7	-0.3	0.3	0.1	0.4	1.2
Arm fat-free mass (right)	0.3	1.3	2.8	-0.4	1.0	1.7	1.5	-0.4	0.6	1.7	1.0
Health satisfaction	0.3	0.4	1.2	0.5	-0.4	-0.9	-0.0	0.1	1.1	-0.7	-0.5
Heart disease (mother)	0.3	0.4	1.3	0.3	0.4	-0.3	0.7	-0.8	0.0	0.5	1.2
Arm predicted mass (right)	0.3	1.5	3.1	-0.4	1.0	1.6	1.6	-0.6	0.7	1.8	1.2
Pulse rate, automated reading	0.3	1.0	5.3	-0.2	0.5	-0.3	-2.3	0.9	-1.1	-0.3	-0.6
Comparative height size at age 10	0.3	1.7	6.7	-0.5	-1.0	-0.5	-2.6	1.0	-1.3	-0.7	-1.5
Chest pain or discomfort	0.3	0.4	1.3	1.1	0.1	0.1	0.7	0.1	1.1	-0.2	0.7
Supplements: Vitamin C	0.3	0.4	0.9	0.9	-0.9	-1.0	-0.7	0.1	-0.0	-0.6	-0.2
Average weekly red wine intake	0.3	0.4	1.2	0.8	-0.3	-0.5	1.1	0.3	0.9	-0.3	0.1
Mood swings	0.3	0.5	1.6	1.3	-0.4	-0.6	-0.2	0.5	0.2	-1.0	-0.4
Ever had bowel cancer screening	0.3	0.3	0.6	-0.5	0.5	0.8	0.0	-0.7	0.7	0.1	0.5
Friendships satisfaction	0.3	0.4	1.0	-0.6	-0.4	-1.0	-0.7	0.4	-1.0	-0.1	-0.1
Back pain experienced in last month	0.3	0.5	2.5	-0.4	0.2	-0.4	-0.1	0.3	-1.6	1.0	0.4
Illnesses of father: None of the above (group 1)	0.3	0.4	0.7	-0.8	0.8	0.6	0.8	0.1	0.9	-0.1	0.3
Tinnitus: Yes, now most or all of the time	0.3	0.4	1.0	0.3	0.4	0.3	-0.6	1.0	-1.0	-0.3	-0.4
Risk taking	0.3	0.5	1.4	-1.2	1.0	0.5	-0.4	0.4	0.7	0.5	0.3
Unable to work because of sickness or disability	0.3	0.4	1.5	-0.4	1.2	-0.4	0.3	-0.5	0.2	0.5	1.0
Pain experienced in last month	0.3	0.4	1.4	-0.5	1.1	0.7	-0.0	0.2	1.2	-0.1	0.3
Arm predicted mass (left)	0.3	1.5	4.2	-0.7	1.1	1.8	1.3	-0.2	0.2	2.0	1.2
Worry (Nagel 2018)	0.2	0.4	0.9	0.9	0.3	0.7	-0.1	-0.0	0.9	-0.2	0.8
Alzheimer’s Disease (in father)	0.2	0.2	0.9	-0.0	0.5	0.9	-0.1	-0.5	0.2	0.3	0.1
Primary Biliary Cirrhosis	0.2	0.2	1.3	-0.3	0.3	-0.3	-0.1	0.3	0.2	-0.5	-1.1
Rheumatoid Arthritis	0.2	0.3	0.8	-0.3	0.9	0.8	0.7	-0.2	-0.2	-0.1	-0.4
Neuroticism	0.2	0.4	1.4	0.4	0.0	0.0	-1.2	0.9	0.4	-0.5	0.2
Townsend deprivation index at recruitment	0.2	0.3	1.7	1.3	0.1	-0.4	0.1	0.2	-0.4	0.4	0.6
Financial difficulties in last 2 years	0.2	0.2	0.8	0.6	-0.4	-0.4	0.0	0.9	0.4	-0.4	0.2
Medication: Simvastatin	0.2	0.3	0.9	0.6	0.6	-0.2	-0.3	-0.6	0.9	-0.7	0.5
Trunk fat-free mass	0.2	1.1	3.1	-0.9	0.6	1.6	0.9	0.4	-0.3	1.8	1.0
Worrier / anxious feelings	0.2	0.4	1.4	0.1	0.5	1.2	-0.3	0.6	0.7	-0.3	0.6
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.2	-0.3	-0.1	-0.4	0.1	-0.1	-1.1	0.9	0.1
Depression (self-reported)	0.2	0.3	1.0	0.1	-0.5	-0.7	-1.0	0.7	-0.0	-0.3	0.4
Trunk predicted mass	0.2	1.1	3.1	-0.9	0.6	1.6	0.8	0.4	-0.3	1.8	1.0
Length of working week for main job	0.2	0.2	0.7	0.0	0.1	-0.1	-0.2	-0.7	-0.7	0.8	-0.2
Birth weight of first child	0.2	0.4	2.1	0.1	-0.2	0.7	0.7	-0.4	1.4	-0.3	0.4
Pulse wave peak to peak time	0.2	0.2	0.5	0.7	-0.3	-0.6	0.7	-0.0	0.5	-0.3	0.5
Shortness of breath walking on level ground	0.2	0.3	0.5	-0.7	0.4	0.6	0.4	-0.4	0.7	0.5	0.2
Age at last live birth	0.2	0.2	0.6	-0.1	-0.4	-0.6	0.8	-0.4	-0.5	-0.6	0.2
Neuroticism (Nagel 2018)	0.1	0.1	0.3	-0.2	0.5	0.4	-0.3	0.4	-0.1	0.4	0.5
Major Depression (MDD)	0.1	0.2	0.5	0.6	-0.7	-0.1	0.4	-0.3	-0.3	0.1	0.3
Reaction Time	0.1	0.3	0.9	0.7	0.7	0.0	1.0	-0.3	0.1	0.3	-0.1
Neuroticism (2016)	0.1	0.1	0.5	-0.1	0.7	-0.0	-0.1	0.1	0.1	-0.1	0.2
Hypothyroidism (self reported)	0.1	0.3	0.9	0.2	0.4	-0.2	0.2	-0.1	-0.6	0.9	0.9
Tanning	0.1	1.0	4.8	2.2	-0.7	0.0	1.2	-0.8	-0.0	0.2	-0.7
Hearing difficulty/problems: Yes	0.1	0.2	0.7	0.2	-0.0	0.1	-0.8	0.8	-0.7	0.1	-0.1
Ever had hysterectomy (womb removed)	0.1	0.2	0.8	0.0	-0.0	0.3	0.1	0.4	0.9	0.3	-0.0
Qualifications: CSEs or equivalent	0.1	0.2	0.5	0.1	-0.0	-0.1	-0.5	-0.6	-0.4	-0.7	-0.5
Mouth/teeth dental problems	0.1	0.1	0.6	0.7	-0.2	-0.3	0.0	0.2	0.1	-0.1	0.2
Alcohol intake versus 10 years previously	0.1	0.1	0.6	-0.3	0.8	0.1	-0.2	-0.3	-0.0	-0.0	-0.2
Ever highly irritable/argumentative for 2 days	0.1	0.2	0.9	-0.0	0.0	0.1	0.5	-0.4	-0.2	0.2	0.9
Medication: Paracetamol	0.1	0.2	0.5	0.4	0.5	-0.1	-0.7	0.4	0.0	-0.5	-0.2
Neck or shoulder pain in last month	0.1	0.2	0.5	0.1	0.5	0.2	0.7	0.1	0.7	-0.0	0.3
Medication: Aspirin	0.1	0.1	0.5	0.4	0.4	-0.1	-0.0	0.1	0.5	-0.7	0.2
Illnesses of father: Heart disease	0.1	0.2	0.3	-0.5	-0.5	-0.5	0.0	-0.6	0.0	-0.4	-0.3
Eye problems/disorders: Cataract	0.1	0.2	0.7	0.4	-0.3	-0.1	0.2	-0.0	0.8	-0.2	0.4
Osteoporosis (self-reported)	0.1	0.2	0.7	0.2	-0.5	-0.0	-0.5	0.2	0.2	-0.8	-0.3
Medication: Aspirin	0.1	0.1	0.4	0.3	0.5	-0.1	-0.2	0.6	0.2	-0.6	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.7	0.1	-0.2	0.2	-0.5	0.4	0.8	-0.2	-0.1
Miserableness	0.1	0.1	0.4	-0.0	0.1	0.2	-0.0	-0.3	-0.5	0.6	0.1
Medication: Paracetamol	0.1	0.1	0.7	0.8	0.5	0.0	-0.1	0.1	0.4	-0.1	0.2
Medication: Atorvastatin	0.1	0.1	0.7	-0.2	0.2	-0.2	-0.0	-0.3	0.2	-0.1	0.9
Ever had prostate specific antigen (PSA) test	0.1	0.2	0.3	-0.3	-0.5	-0.4	-0.0	0.5	0.4	-0.5	0.4
Cholesterol lowering medication	0.1	0.1	0.9	-0.2	0.9	0.2	-0.1	-0.2	0.0	0.1	-0.1
Depressed Affect (Nagel 2018)	0.0	0.1	0.1	0.4	-0.3	0.3	0.4	0.1	0.0	0.1	0.0
Hair Pigment	0.0	1.3	6.2	0.1	0.5	-0.0	-1.4	0.6	-1.2	0.4	-2.5
Fractured/broken bones in last 5 years	0.0	0.0	0.1	-0.0	0.3	0.2	-0.0	0.1	0.1	0.1	-0.3

Hub : Genes

UBE2R2

Models

Trait associations