TWAS hub - UCKL1AS

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0207	0.0112	0.0046	-0.001	0.004	-0.001	NA	-0.001	0.4800	0.03900	0.5500	NA	1.0000
2	TCGA	Thyroid Carcinoma	0.0450	0.0220	0.0016	0.024	0.031	0.021	NA	0.024	0.0019	0.00046	0.0034	NA	0.0021

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Birth weight	8.2	17.9	34.3	1.2	5.9
High blood pressure	5.9	16.3	31.9	0.9	-5.6
Hypertension (Self-reported)	5.8	16.1	30.9	1.1	-5.6
Illnesses of siblings	5.5	7.8	8.7	2.6	3.0
Medication: Atorvastatin	5.3	6.5	12.8	0.4	-3.6
Systolic Blood Pressure	5.2	26.0	51.2	0.9	-7.2
Osteoporosis (self-reported)	5.2	6.5	12.0	1.0	3.5
Medication: Blood pressure	5.2	10.0	19.0	1.0	-4.4
Vascular/heart problems diagnosed by doctor	4.9	13.3	26.2	-0.6	5.1
Medication: Lisinopril	4.5	5.8	6.6	2.2	-2.6
Seen a psychiatrist for nerves, anxiety, tension or depression	4.2	5.5	10.8	3.3	0.4
Shortness of breath walking on level ground	4.2	5.0	9.8	3.1	-0.2
High blood pressure (mother)	4.1	5.8	11.2	-0.6	-3.3
Hand grip strength (right)	4.0	10.8	20.9	0.9	-4.6
Cardiovascular Disease	3.9	12.7	25.4	-0.1	-5.0
Heart attack	3.8	4.9	9.7	0.0	-3.1
Pulse wave Arterial Stiffness index	3.7	4.3	6.2	-2.5	-1.6
Basal cell carcinoma (self-reported)	3.6	4.2	7.7	-2.8	0.9
Pulse wave peak to peak time	3.5	4.1	6.2	2.5	1.4
Heart attack/myocardial infarction (self-reported)	3.4	4.3	8.6	-0.1	-2.9
Supplements: Zinc	3.3	3.6	4.2	-1.7	-2.1
Medication: Bendroflumethiazide	3.3	5.1	6.8	1.8	-2.6
Irritability	3.2	5.4	9.3	-1.2	3.0
Birth weight of first child	3.1	5.7	10.8	-0.7	3.3
Medication for cholesterol	3.1	4.7	8.9	-0.6	3.0
Cholesterol lowering medication	3.1	4.5	9.1	0.1	-3.0
Qualifications: CSEs or equivalent	3.0	3.9	6.4	1.2	-2.5
Glaucoma (self-reported)	3.0	3.5	5.7	1.1	2.4
Number of full sisters	2.9	3.6	4.2	-1.7	-2.0
Pack years adult smoking proportion	2.8	4.3	6.6	2.6	-1.4
Medication: Atenolol	2.8	3.5	4.5	1.6	-2.1
High blood pressure (siblings)	2.8	4.0	5.7	-1.5	-2.4
Irritable Bowel Disease (IBD)	2.7	6.5	11.4	1.3	3.4
Systolic blood pressure, automated reading	2.7	7.9	15.2	0.8	-3.9
Impedance of arm (left)	2.7	12.3	20.5	-2.0	4.5
Medication: Blood pressure	2.7	4.8	9.6	0.2	-3.1
Medication for cholesterol, blood pressure or diabetes	2.6	4.3	8.5	-0.2	2.9
Diastolic blood pressure, automated reading	2.6	8.1	15.0	1.1	-3.9
Angina	2.5	3.2	6.3	0.4	-2.5
Medication: Omeprazole	2.5	3.0	5.0	2.2	1.0
Medication: Aspirin	2.5	3.3	6.6	0.0	-2.6
Angina (self-reported)	2.4	3.2	6.2	0.5	-2.5
Illnesses of father: Heart disease	2.4	3.3	5.8	-1.0	-2.4
Tinnitus: Yes, now most or all of the time	2.4	2.8	4.1	1.2	-2.0
Hand grip strength (left)	2.3	6.0	11.5	0.8	-3.4
Hayfever, allergic rhinitis or eczema	2.3	5.0	9.8	-0.4	3.1
Impedance of arm (right)	2.3	10.9	17.7	-2.0	4.2
Breast cancer (self-reported)	2.2	2.7	3.2	-1.8	1.4
Ever smoked	2.2	3.9	4.7	1.8	2.2
Alzheimer’s Disease (in father)	2.1	2.3	4.6	2.2	0.0
Maternal smoking around birth	2.1	3.0	5.9	2.4	-0.4
Medication: Lansoprazole	2.1	2.4	4.2	-2.1	-0.8
Comparative body size at age 10	2.1	5.7	10.6	3.3	0.9
Medication for pain relief, constipation, heartburn	2.1	3.6	6.6	-2.6	0.8
Pain type(s) experienced in last month: Hip pain	2.1	2.6	3.1	1.8	1.4
Townsend deprivation index at recruitment	2.0	2.8	5.2	-2.3	-0.6
Qualifications: College or University degree	2.0	6.2	7.9	-2.8	2.1
Pack years of smoking	2.0	2.9	4.5	2.1	-1.1
Relative age of first facial hair	1.9	3.9	7.2	-0.7	-2.7
Medication: Omeprazole (e.g. Zanprol)	1.9	2.3	3.8	2.0	0.9
Body Mass Index (BMI) (2010)	1.8	2.4	4.9	2.2	-0.0
Severe depression (siblings)	1.8	2.0	3.3	0.8	1.8
Emphysema/chronic bronchitis	1.8	2.0	4.0	2.0	0.1
Average weekly beer plus cider intake	1.8	2.7	4.8	2.2	0.7
Past tobacco smoking	1.7	3.2	3.3	-1.7	-1.8
Had other major operations	1.7	2.0	3.3	-0.9	1.8
Serious illness, injury or assault of a close relative in last 2 years	1.7	2.0	3.4	-1.8	-0.8
Crohns Disease (2017)	1.6	3.5	6.7	0.5	2.6
Crohns Disease (2012)	1.6	2.6	5.3	-0.0	2.3
Other serious medical condition/disability diagnosed by doctor	1.6	2.0	3.2	1.8	1.0
Breastfed as a baby	1.6	2.0	2.3	-1.3	1.5
Ever highly irritable/argumentative for 2 days	1.6	1.9	3.0	1.7	-0.9
Commuting to job workplace: Walk	1.6	1.8	3.5	-0.2	1.9
Medication: Aspirin	1.6	2.0	4.1	0.1	-2.0
Impedance of whole body	1.6	8.1	11.7	-2.1	3.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.5	2.0	4.0	-0.1	-2.0
Medication: Paracetamol	1.5	2.5	3.7	1.2	-1.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.8	3.2	0.6	1.8
Ulcerative Colitis (UC)	1.4	2.5	4.5	0.8	2.1
Average weekly fortified wine intake	1.4	1.6	2.6	0.8	-1.6
Relative age voice broke	1.4	2.2	2.7	-1.3	-1.6
Age when periods started (menarche)	1.4	3.4	3.7	-1.9	-1.8
Medication: Levothyroxine sodium	1.4	2.4	4.6	-2.1	-0.5
Allergy	1.4	3.2	6.3	0.4	-2.5
Medication: Cholesterol lowering	1.4	2.2	4.1	-0.5	-2.0
Health satisfaction	1.4	1.9	3.7	1.9	-0.1
Average weekly champagne plus white wine intake	1.4	1.9	3.0	-0.9	1.7
High cholesterol (Self-reported)	1.4	2.4	4.8	0.1	-2.2
Fractured/broken bones in last 5 years	1.4	1.8	3.5	1.9	0.5
Bipolar Disorder (2018)	1.3	2.0	3.9	-0.2	2.0
Allergy or Eczema	1.3	3.5	7.0	0.2	2.6
Trunk fat percentage	1.3	5.1	5.6	2.2	2.4
Diverticular disease/diverticulitis (self-reported)	1.3	1.6	2.3	1.5	-0.9
Pain all over the body in last month	1.3	1.4	2.7	1.6	-0.1
Medication: Ventolin 100micrograms inhaler	1.3	1.7	1.7	1.3	1.3
Body fat percentage	1.3	5.3	6.8	2.6	1.9
Medication: Seretide 50 evohaler	1.3	1.5	2.1	1.5	1.0
Suffer from ‘nerves’	1.3	2.0	3.2	1.8	0.9
Knee pain experienced in last month	1.3	2.0	2.9	1.1	1.7
Smoking status: Previous	1.3	2.0	2.0	1.4	1.4
Financial situation satisfaction	1.3	1.6	2.7	0.7	-1.6
Supplements: Calcium	1.3	1.4	1.9	-1.4	1.0
Body mass index (BMI)	1.2	5.2	10.1	3.2	-0.6
Headache pain in last month	1.2	2.1	3.5	-0.8	-1.9
Leg fat percentage (right)	1.2	4.3	8.1	2.9	0.8
Number of full brothers	1.2	1.5	2.6	-1.6	0.6
Number of self-reported non-cancer illnesses	1.2	2.2	3.7	1.9	-0.8
Leg fat percentage (left)	1.2	4.4	8.4	2.9	0.7
Deep venous thrombosis (DVT) (self-reported)	1.2	1.6	2.8	-1.7	0.6
Medication: Ramipril	1.1	1.4	2.5	-0.5	-1.6
Medication: Simvastatin	1.1	1.6	1.7	-1.3	-1.2
Hip circumference	1.1	4.8	8.4	2.9	1.1
Qualifications: A levels/AS levels or equivalent	1.1	2.5	3.9	-2.0	1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.7	2.9	0.7	-1.7
Medication: Amlodipine	1.1	1.5	3.0	-0.2	-1.7
Chronic bronchitis/emphysema (mother)	1.1	1.3	2.4	0.4	1.6
Leg fat mass (right)	1.1	4.4	8.8	3.0	-0.0
Ever had bowel cancer screening	1.1	1.3	1.9	-0.8	1.4
Eye problems/disorders: Glaucoma	1.1	1.4	2.3	1.5	0.6
Alcohol drinker status: Never	1.1	1.3	2.7	1.6	0.0
Alcohol drinker status: Previous	1.1	1.3	1.6	-1.3	1.0
Leg fat mass (left)	1.1	4.2	8.4	2.9	-0.0
Alzheimer’s Disease (in mother)	1.0	1.2	2.1	0.6	1.4
Ulcerative Colitis	1.0	1.4	2.8	0.3	1.7
Lung FEV1/FVC ratio	1.0	5.2	8.6	2.9	-1.3
Taking other prescription medications	1.0	1.5	2.4	0.8	1.6
Had menopause	1.0	1.3	1.7	1.3	0.9
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.3	3.9	0.8	-2.0
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	1.4	1.2	1.1
Father’s age at death	1.0	1.3	2.4	-0.5	1.5
Arm fat mass (right)	1.0	3.9	7.8	2.8	0.3
Exposure to tobacco smoke at home	1.0	1.1	1.4	0.9	-1.2
Pulse wave reflection index	1.0	1.2	1.9	-1.4	-0.7
Arm fat percentage (left)	1.0	4.1	6.2	2.5	1.4
Mother’s age at death	1.0	1.3	2.6	-0.1	1.6
Alzheimer’s Disease (including proxy)	0.9	1.3	1.3	1.2	1.1
Breast Cancer	0.9	2.3	4.3	-0.5	-2.1
Heel T-Score	0.9	7.5	10.6	-2.1	-3.2
BMI	0.9	5.2	10.3	3.2	-0.4
Ever used hormone-replacement therapy (HRT)	0.9	1.2	1.9	1.4	0.6
Vitamin and mineral supplements	0.9	1.2	1.5	-1.0	1.2
Diabetes (mother)	0.9	1.2	2.2	-1.5	-0.4
Multivitamins +/- minerals	0.9	1.2	1.9	0.7	-1.4
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	1.9	1.4	0.5
Arm fat percentage (right)	0.9	3.7	6.0	2.5	1.2
Depression (self-reported)	0.9	1.1	1.2	-1.1	-1.0
Loud music exposure frequency	0.9	1.0	2.0	1.4	-0.2
Blood clot in the leg (DVT)	0.9	1.2	2.1	-1.4	0.5
Exposure to tobacco smoke outside home	0.9	1.2	1.8	1.3	-0.7
Illnesses of siblings: Diabetes	0.9	1.2	2.0	-1.4	-0.5
Handedness (chirality/laterality): Left-handed	0.9	1.1	1.2	1.0	1.1
Arm fat mass (left)	0.9	3.7	7.2	2.7	0.3
Prostate Cancer	0.8	1.1	2.2	-1.5	0.3
Rheumatoid Arthritis	0.8	1.1	1.2	1.1	1.0
Blood White Count	0.8	6.0	11.7	0.5	-3.4
Average weekly spirits intake	0.8	1.0	2.0	1.4	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.7	3.4	-0.0	-1.9
Trunk fat mass	0.8	3.6	4.7	2.2	1.6
Whole body fat mass	0.8	3.5	6.3	2.5	0.9
Arm predicted mass (right)	0.8	4.3	4.6	2.1	-2.0
Leg pain on walking	0.8	1.0	1.4	1.2	-0.7
Supplements: Vitamin C	0.8	1.0	1.9	0.1	-1.4
Osteoarthritis (self-reported)	0.8	1.0	1.2	1.1	0.9
Medication: Gliclazide	0.8	0.9	1.4	1.2	-0.7
Medication: Paracetamol	0.8	1.2	1.9	0.6	-1.4
Arm fat-free mass (left)	0.8	4.0	4.2	1.9	-2.0
Ever had prostate specific antigen (PSA) test	0.8	0.9	1.7	-1.3	0.4
Ever depressed for a whole week	0.8	1.0	1.6	1.3	-0.6
Arm predicted mass (left)	0.8	4.1	4.2	2.1	-2.0
Fasting Glucose	0.7	0.8	1.0	-0.8	-1.0
Diabetes (father)	0.7	0.9	1.8	-0.1	1.3
Waist circumference	0.7	2.6	5.0	2.2	0.4
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	2.0	-1.4	-0.5
Arm fat-free mass (right)	0.7	3.5	4.0	1.7	-2.0
Migraine (self-reported)	0.7	0.9	1.6	1.3	-0.4
Heart disease (mother)	0.7	0.8	1.5	-0.4	-1.2
Chest pain or discomfort	0.7	1.1	1.9	-1.4	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.8	1.5	-1.2	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	2.3	-1.5	-0.1
Miserableness	0.7	1.2	2.5	-0.0	-1.6
Triglycerides	0.6	1.0	2.1	0.0	-1.4
Hypothyroidism (self reported)	0.6	1.3	2.6	-1.6	0.1
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	0.8	0.9	-0.7
Supplements: Glucosamine	0.6	0.8	1.3	1.2	0.4
Mouth/teeth dental problems	0.6	1.0	1.7	0.5	-1.3
Weight	0.6	2.9	5.7	2.4	0.0
Mouth/teeth dental problems: Dentures	0.6	1.0	1.2	1.1	0.9
Hypothyroidism/myxoedema (self-reported)	0.6	1.1	2.1	-1.5	0.2
Average weekly red wine intake	0.6	0.8	1.0	-1.0	-0.8
Long-standing illness, disability or infirmity	0.6	0.9	1.8	-0.2	1.3
Intelligence (Savage-Jansen 2018)	0.5	1.4	1.9	-1.0	1.4
Ovarian Cancer	0.5	0.6	1.2	-1.1	-0.1
LDL Cholesterol	0.5	0.8	1.6	-0.0	-1.2
Waist Hip Ratio (WHR)	0.5	2.2	4.5	-2.1	-0.1
Smoking Status	0.5	1.1	1.9	0.5	1.4
Chronotype (morning person)	0.5	1.1	1.5	0.9	1.2
Frequency of depressed mood in last 2 weeks	0.5	0.7	0.7	0.8	-0.8
Impedance of leg (right)	0.5	2.5	2.6	-1.6	1.6
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	0.6	0.8	-0.7
Sitting height	0.5	3.2	5.3	-2.3	-1.1
Number of incorrect matches in round	0.5	0.8	1.4	-0.4	-1.2
Hair/balding pattern: Pattern 3	0.5	0.7	1.0	-1.0	0.7
Happiness	0.5	0.5	1.1	1.0	-0.2
Neck or shoulder pain in last month	0.5	0.8	1.3	-1.1	0.5
Comparative height size at age 10	0.5	2.6	5.0	0.4	2.2
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	2.3	-1.5	0.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	1.2	1.1	0.1
Illnesses of father: None of the above (group 1)	0.5	0.6	1.0	0.4	1.0
Illnesses of father: High blood pressure	0.5	0.7	1.1	-1.1	-0.5
Number of operations (self-reported)	0.5	0.8	1.2	-0.5	1.1
Myopia	0.5	0.7	1.3	-0.4	1.1
Pain experienced in last month	0.5	0.8	1.0	-1.0	-0.8
Depression (Nagel 2018)	0.4	0.7	1.0	0.6	-1.0
HDL Cholesterol	0.4	0.7	1.3	0.1	1.1
Primary Biliary Cirrhosis	0.4	0.6	0.8	0.9	-0.6
Respiratory disease	0.4	0.8	1.5	-1.2	-0.4
Type 2 Diabetes (T2D) (2018)	0.4	0.8	1.5	0.0	1.2
Ever had hysterectomy (womb removed)	0.4	0.5	0.8	0.4	-0.9
Medication: Co-codamol	0.4	0.5	0.8	0.3	-0.9
Stomach or abdominal pain in last month	0.4	0.5	0.5	0.7	0.6
Chronic bronchitis/emphysema (father)	0.4	0.5	0.7	0.8	0.6
Impedance of leg (left)	0.4	2.1	2.2	-1.4	1.5
Alcohol usually taken with meals	0.4	0.6	1.1	-1.1	-0.4
Hearing difficulty/problems with background noise	0.4	0.7	1.4	0.2	1.2
Forced vital capacity (FVC)	0.4	1.6	3.0	-1.7	-0.5
Trunk fat-free mass	0.4	2.5	4.6	0.6	-2.1
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	1.0	0.5	-1.0
Prospective memory result	0.4	0.5	0.6	0.8	0.7
Trunk predicted mass	0.4	2.5	4.6	0.6	-2.1
Forced vital capacity (FVC), Best measure	0.4	1.3	2.6	-1.6	-0.1
Worry too long after embarrassment	0.4	0.6	1.0	1.0	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.4	0.7	0.8	0.4
Pulse rate, automated reading	0.4	1.2	1.9	1.4	0.7
Family relationship satisfaction	0.4	0.5	0.9	0.9	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	0.5	-0.7	-0.7
Illness, injury, bereavement, stress in last 2 years	0.4	0.4	0.8	0.9	0.3
Whole body fat-free mass	0.4	2.1	2.5	1.3	-1.6
Mood swings	0.4	0.7	1.1	0.6	-1.1
Diabetes diagnosed by doctor	0.4	0.6	0.9	-0.7	0.9
Asthma (self-reported)	0.4	0.8	1.4	-1.2	0.5
Whole body water mass	0.4	2.2	2.9	1.3	-1.7
Wears glasses or contact lenses	0.4	0.4	0.8	0.9	-0.1
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.0	1.0	0.2
Basal metabolic rate	0.4	2.0	2.5	1.6	-1.2
Verbal and Numeric Reasoning (VNR)	0.3	0.8	1.0	-0.7	1.0
Lupus	0.3	0.4	0.7	-0.8	-0.3
Number of treatments/medications taken	0.3	0.6	1.0	1.0	-0.5
Sensitivity / hurt feelings	0.3	0.5	0.8	0.9	-0.5
Medication for hormone replacement therapy	0.3	0.3	0.4	0.5	-0.6
Medication: Metformin	0.3	0.4	0.7	-0.8	-0.1
Current tobacco smoking	0.3	0.5	1.0	1.0	0.3
Leg predicted mass (left)	0.3	1.5	2.9	1.7	-0.4
Hair/balding pattern: Pattern 2	0.3	0.4	0.8	-0.1	0.9
Qualifications: None of the above	0.3	0.7	0.7	0.8	-0.8
Financial difficulties in last 2 years	0.3	0.3	0.4	-0.6	-0.5
Diabetes (self-reported)	0.3	0.5	0.9	-0.2	1.0
Falls in the last year	0.3	0.4	0.6	0.5	0.8
Asthma	0.3	0.6	1.1	-1.1	0.4
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	0.6	0.8	0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	0.6	-0.8	0.2
Overall health rating	0.3	0.6	0.7	0.7	-0.8
Leg fat-free mass (right)	0.3	1.5	2.5	1.6	-0.6
Friendships satisfaction	0.3	0.4	0.4	0.6	-0.7
Leg predicted mass (right)	0.3	1.6	2.6	1.6	-0.7
Ever taken oral contraceptive pill	0.3	0.3	0.7	0.0	-0.8
Risk taking	0.3	0.5	0.7	-0.9	-0.5
Unable to work because of sickness or disability	0.3	0.4	0.5	0.6	-0.7
Bipolar Disorder or Schizophrenia	0.2	0.5	1.1	-0.1	1.0
Depressed Affect (Nagel 2018)	0.2	0.4	0.4	-0.6	-0.7
Mean Putamen Volume	0.2	0.2	0.4	0.6	0.3
HbA1C	0.2	0.2	0.3	-0.6	-0.1
Neuroticism (2016)	0.2	0.3	0.4	0.7	-0.3
Schizophrenia (2014)	0.2	0.5	0.8	-0.5	0.9
Blood Red Count	0.2	2.4	4.7	-2.2	-0.4
Height	0.2	3.6	4.7	-2.2	1.6
Hair Pigment	0.2	6.1	7.5	2.7	2.2
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.2	0.4	-0.4
Leg fat-free mass (left)	0.2	1.3	2.5	1.6	-0.3
Fed-up feelings	0.2	0.3	0.5	0.1	-0.7
Time employed in main current job	0.2	0.3	0.5	0.7	0.3
Alcohol intake versus 10 years previously	0.2	0.2	0.4	0.7	0.1
Worrier / anxious feelings	0.2	0.3	0.6	0.8	0.1
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	0.9	-0.5	-1.0
Pulse rate	0.2	0.3	0.5	-0.2	-0.7
Noisy workplace	0.2	0.2	0.4	0.2	-0.6
Lung cancer (father)	0.2	0.2	0.4	-0.7	-0.2
Standing height	0.2	1.5	2.0	-1.4	1.0
Tense / ‘highly strung’	0.2	0.3	0.4	0.4	0.6
Number of children fathered	0.2	0.2	0.4	0.1	-0.7
Age at first live birth	0.2	0.4	0.7	0.8	-0.1
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.2	-0.4	0.5
Alcohol intake frequency.	0.2	0.5	0.9	0.2	-0.9
Eye problems/disorders: Cataract	0.2	0.2	0.2	0.4	-0.4
Back pain experienced in last month	0.2	0.2	0.3	0.5	0.5
Guilty feelings	0.2	0.3	0.5	-0.7	0.1
Heart disease (siblings)	0.2	0.2	0.2	-0.5	-0.5
Worry (Nagel 2018)	0.1	0.2	0.3	0.5	0.3
Reaction Time	0.1	0.2	0.2	-0.5	-0.3
Blood Eosinophil Count	0.1	0.4	0.7	-0.3	0.9
Blood Platelet Count	0.1	1.5	3.0	-0.3	-1.7
Lung FVC	0.1	0.4	0.8	0.3	0.9
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.1	0.1	-0.3	-0.3
Neuroticism score	0.1	0.1	0.2	0.3	0.4
Number of live births	0.1	0.2	0.3	0.6	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	0.5	-0.7	-0.5
Hair/balding pattern: Pattern 4	0.1	0.1	0.2	-0.5	-0.2
Peak expiratory flow (PEF)	0.1	0.2	0.4	0.6	-0.0
Mouth/teeth dental problems: Bleeding gums	0.1	0.2	0.3	-0.1	0.6
Gout (self-reported)	0.1	0.1	0.3	-0.1	-0.5
Eye problems/disorders: None of the above	0.1	0.1	0.2	-0.2	-0.5
Medication: Ibuprofen	0.1	0.1	0.1	0.3	0.1
Medication: Allopurinol	0.1	0.1	0.1	0.3	-0.3
Mean time to correctly identify matches	0.1	0.1	0.2	-0.0	0.5
Had major operations	0.1	0.1	0.1	0.0	-0.3
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.1	0.3	-0.4
Qualifications: nursing, teaching	0.1	0.2	0.3	0.3	-0.6
Mineral and other dietary supplements	0.1	0.2	0.3	-0.1	-0.6
Smoking status: Current	0.1	0.2	0.5	0.7	-0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	0.5	-0.7	0.3
Hearing aid user	0.1	0.1	0.1	0.3	0.3
Age started oral contraceptive pill	0.1	0.1	0.3	-0.5	-0.1
Neuroticism (Nagel 2018)	0.0	0.1	0.1	-0.4	0.3
Schizophrenia (2018)	0.0	0.0	0.0	-0.2	-0.1
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.0	0.0	0.0	-0.0	-0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0
Neuroticism	0.0	0.0	0.0	0.2	0.2
Tanning	0.0	0.5	0.7	0.8	-0.6
Hearing difficulty/problems: Yes	0.0	0.1	0.2	-0.4	0.0
Serious illness, injury or assault to yourself	0.0	0.1	0.1	-0.3	0.1
Nervous feelings	0.0	0.1	0.1	0.1	0.4
Fluid intelligence score	0.0	0.0	0.0	0.0	-0.1
Illnesses of mother	0.0	0.0	0.0	-0.1	-0.0
Length of working week for main job	0.0	0.0	0.1	0.1	-0.2
Wheeze or whistling in the chest in last year	0.0	0.1	0.1	0.3	-0.1
Age at last live birth	0.0	0.0	0.0	0.0	-0.1
Loneliness, isolation	0.0	0.1	0.1	-0.1	-0.3
Commuting to job workplace: Public transport	0.0	0.0	0.1	0.1	-0.3
Commuting to job workplace: Cycle	0.0	0.0	0.0	0.1	-0.1

Hub : Genes

UCKL1AS

Models

Trait associations