TWAS hub - UQCRC1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Coronary	0.7930	0.0510	3.1e-05	0.019	NA	0.014	NA	-0.007	0.075	NA	0.11	NA	0.65
2	GTEx	Heart Left Ventricle	0.0652	0.0371	9.5e-03	-0.005	NA	-0.003	NA	-0.005	0.690	NA	0.54	NA	0.72

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Father’s age at death	6.5	8.7	11.9	2.4	-3.5
Type 2 Diabetes (T2D) (2012)	5.5	6.3	11.7	-1.0	3.4
Pulse rate, automated reading	5.4	17.4	34.1	-0.8	5.8
Medication for cholesterol, blood pressure or diabetes	4.9	8.2	12.0	2.1	-3.5
Crohns Disease (2012)	4.8	7.7	8.5	2.6	-2.9
Diabetes (mother)	4.6	5.9	7.0	-2.6	2.2
Medication: Blood pressure	4.4	7.8	10.1	-2.3	3.2
Irritable Bowel Disease (IBD)	4.3	10.1	10.2	3.2	-3.2
Medication: Metformin	4.2	5.9	8.9	-3.0	1.7
Mouth/teeth dental problems: Loose teeth	4.0	4.8	8.3	-2.9	1.1
Migraine (self-reported)	4.0	5.0	9.9	-0.2	-3.1
Mean Putamen Volume	3.7	4.3	6.5	1.4	-2.5
Crohns Disease (2017)	3.3	7.2	9.4	3.1	-2.2
Ulcerative Colitis	3.2	4.6	7.1	1.4	-2.7
Medication: Atenolol	3.1	3.9	5.8	-1.4	2.4
Medication: Lansoprazole	3.1	3.5	4.1	-1.7	2.0
Allergy	3.0	7.0	9.1	-3.0	2.2
Diastolic blood pressure, automated reading	2.9	8.8	12.4	-2.3	3.5
Ulcerative Colitis (UC)	2.8	5.2	5.9	2.1	-2.4
Comparative body size at age 10	2.8	7.7	13.9	1.2	-3.7
Blood White Count	2.7	19.7	25.5	-3.7	5.0
Primary Biliary Cirrhosis	2.6	3.7	6.7	0.9	-2.6
Systolic Blood Pressure	2.6	12.8	18.8	-2.6	4.3
Heart disease (siblings)	2.5	3.1	6.0	-2.4	0.5
High blood pressure (siblings)	2.4	3.4	5.8	-2.4	1.0
Major Depression (MDD)	2.3	2.8	4.0	-2.0	1.2
Illnesses of siblings	2.3	3.2	6.2	2.5	0.3
Birth weight	2.3	5.1	7.1	1.8	-2.7
Had major operations	2.3	2.7	2.7	-1.6	1.6
Tense / ‘highly strung’	2.2	3.7	4.7	-1.6	2.2
Rheumatoid Arthritis	2.1	2.9	3.4	1.6	-1.9
Depression (self-reported)	2.1	2.6	4.7	0.6	-2.2
Birth weight of first child	2.1	3.8	7.5	0.3	-2.7
Deep venous thrombosis (DVT) (self-reported)	2.1	2.6	4.7	0.8	-2.2
Bipolar Disorder (2011)	2.0	1.9	3.2	0.8	-1.8
Eye problems/disorders: Diabetes related eye disease	2.0	2.2	3.7	-1.9	0.8
Medication: Cholesterol lowering	2.0	3.1	4.7	-1.3	2.2
Worry too long after embarrassment	2.0	3.3	4.5	-1.4	2.1
Medication: Aspirin	2.0	2.6	3.0	-1.7	1.5
Ever taken oral contraceptive pill	2.0	2.3	3.7	-0.9	1.9
Number of operations (self-reported)	2.0	3.0	5.5	-2.3	0.7
Neuroticism	1.9	4.5	4.5	-2.1	2.1
Diabetes (self-reported)	1.9	3.0	5.5	-2.4	0.7
Number of live births	1.9	2.7	4.1	-2.0	1.2
Lung cancer (father)	1.9	2.2	3.5	0.9	-1.9
Pulse wave reflection index	1.9	2.4	4.8	-2.2	-0.1
Ever had bowel cancer screening	1.9	2.2	4.2	0.4	-2.0
Diabetes diagnosed by doctor	1.9	3.2	4.7	-2.2	1.3
Breast Cancer	1.8	4.3	7.6	-1.0	-2.8
Heel T-Score	1.8	14.5	28.8	-0.5	5.4
Smoking Status	1.8	4.3	8.4	0.4	-2.9
Cardiovascular Disease	1.8	6.0	9.6	-1.6	3.1
Medication: Co-codamol	1.8	2.1	3.7	-1.9	0.7
Worrier / anxious feelings	1.8	3.5	4.0	-1.7	2.0
Pulse rate	1.8	3.0	5.6	-0.6	2.4
Pulse wave Arterial Stiffness index	1.8	2.2	2.6	-1.3	1.6
Length of working week for main job	1.8	2.0	4.0	-2.0	-0.3
Blood clot in the leg (DVT)	1.8	2.3	4.1	0.7	-2.0
Depression (Nagel 2018)	1.7	2.5	3.1	1.8	-1.4
Type 2 Diabetes (T2D) (2018)	1.7	3.3	3.7	-1.9	1.7
Time employed in main current job	1.7	1.9	3.8	0.2	-1.9
Myopia	1.7	2.4	4.5	2.1	-0.6
Sitting height	1.6	11.4	22.8	-0.3	4.8
Medication: Amlodipine	1.6	2.2	2.3	-1.4	1.5
Neck or shoulder pain in last month	1.6	2.3	4.5	-2.1	-0.2
Medication: Bendroflumethiazide	1.6	2.5	4.1	-0.9	2.0
Worry (Nagel 2018)	1.5	3.2	5.2	-1.1	2.3
HDL Cholesterol	1.5	2.5	3.9	1.0	-2.0
Systolic blood pressure, automated reading	1.5	4.4	5.3	-2.3	1.9
Stomach or abdominal pain in last month	1.5	1.9	3.7	-1.9	0.3
Number of full brothers	1.5	1.9	2.6	-1.6	-1.1
Qualifications: College or University degree	1.5	4.7	7.9	2.8	-1.2
Commuting to job workplace: Car/motor vehicle	1.5	1.7	2.8	-1.7	-0.8
Handedness (chirality/laterality): Left-handed	1.5	1.8	3.5	-0.2	1.9
Unable to work because of sickness or disability	1.5	1.9	3.5	-0.6	-1.9
Intelligence (Savage-Jansen 2018)	1.4	4.4	5.4	2.3	-1.8
Number of treatments/medications taken	1.4	2.5	4.5	-0.7	2.1
Severe depression (siblings)	1.4	1.5	1.6	-1.2	-1.2
Heart attack	1.4	1.8	3.0	-1.7	0.8
Pain all over the body in last month	1.4	1.5	2.3	-1.5	-0.8
Neuroticism score	1.4	3.0	3.1	-1.7	1.8
Pulse wave peak to peak time	1.4	1.7	1.7	1.3	-1.3
Medication: Lisinopril	1.4	1.8	1.9	-1.4	1.3
Basal cell carcinoma (self-reported)	1.4	1.6	1.7	1.2	-1.3
Heart attack/myocardial infarction (self-reported)	1.4	1.8	3.0	-1.7	0.8
HbA1C	1.3	1.5	2.8	-1.7	0.4
Lupus	1.3	1.9	3.4	0.7	-1.9
Waist Hip Ratio (WHR)	1.3	5.8	8.0	-1.9	2.8
Current tobacco smoking	1.3	2.1	4.2	0.3	-2.0
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	1.7	-1.3	1.1
Chronic bronchitis/emphysema (father)	1.3	1.5	2.7	-1.7	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	1.3	1.6	2.0	1.1	-1.4
Number of children fathered	1.3	1.5	2.9	-1.7	-0.2
Angina (self-reported)	1.3	1.7	2.6	-1.6	0.9
Age at last live birth	1.3	1.9	3.7	1.9	-0.5
Family relationship satisfaction	1.3	1.6	2.5	-0.8	1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.3	1.5	3.1	-1.8	0.2
Irritability	1.3	2.3	4.5	-2.1	-0.3
Fasting Glucose	1.2	1.4	2.6	-0.5	1.6
Age at first live birth	1.2	2.1	4.0	2.0	-0.5
Medication: Atorvastatin	1.2	1.4	2.0	-1.4	0.9
Vascular/heart problems diagnosed by doctor	1.2	3.3	4.5	1.4	-2.1
Allergy or Eczema	1.1	2.9	4.4	2.1	-1.2
Heel bone mineral density (BMD) T-score, automated (right)	1.1	2.6	4.6	0.7	2.2
Hayfever/allergic rhinitis (self-reported)	1.1	1.5	2.8	1.7	-0.3
Illnesses of mother	1.1	1.3	1.9	1.4	-0.9
Exposure to tobacco smoke at home	1.1	1.3	2.2	-0.6	1.5
Qualifications: O levels/GCSEs or equivalent	1.1	1.8	2.4	1.1	-1.5
Medication: Paracetamol	1.1	1.7	3.4	0.4	-1.8
Medication: Omeprazole	1.1	1.3	2.5	-1.6	0.1
Number of full sisters	1.1	1.3	1.7	-1.3	-0.9
Leg pain on walking	1.1	1.4	2.1	1.4	-0.9
Medication for cholesterol	1.1	1.7	3.4	0.1	-1.9
Mineral and other dietary supplements	1.1	1.5	2.9	1.7	-0.4
Average weekly beer plus cider intake	1.1	1.6	3.0	-0.4	1.7
Alcohol drinker status: Previous	1.1	1.2	2.1	-1.4	-0.6
Angina	1.0	1.3	1.8	-1.3	0.9
Prospective memory result	1.0	1.3	2.0	1.4	0.8
Hypertension (Self-reported)	1.0	2.7	4.1	-1.2	2.0
Asthma (self-reported)	1.0	1.9	2.9	1.7	-1.0
Medication: Gliclazide	1.0	1.1	2.0	-1.4	0.5
Ever smoked	1.0	1.7	3.1	0.6	-1.8
Schizophrenia vs Biploar Disorder	0.9	1.2	1.6	0.9	1.3
Alzheimer’s Disease (in mother)	0.9	1.0	2.0	1.4	-0.2
Serious illness, injury or assault to yourself	0.9	1.1	2.1	0.2	-1.5
Nervous feelings	0.9	1.6	3.0	-0.5	1.7
Asthma	0.9	1.8	2.3	1.5	-1.2
Impedance of arm (left)	0.9	4.2	7.7	2.8	0.8
Peak expiratory flow (PEF)	0.9	2.2	4.0	0.6	-2.0
Overall health rating	0.9	1.9	3.7	-1.9	0.4
Smoking status: Current	0.9	1.4	2.8	0.2	-1.7
Blood Red Count	0.8	8.1	15.4	0.9	3.9
Ever used hormone-replacement therapy (HRT)	0.8	1.0	1.6	-0.7	1.3
Ever had hysterectomy (womb removed)	0.8	0.8	1.7	-0.1	1.3
Average weekly fortified wine intake	0.8	1.0	1.9	1.4	-0.3
High blood pressure	0.8	2.4	3.5	-1.1	1.9
Hayfever, allergic rhinitis or eczema	0.8	1.8	3.2	1.8	-0.6
Multivitamins +/- minerals	0.8	1.0	2.1	-0.0	-1.4
Qualifications: None of the above	0.8	1.7	3.4	-1.8	0.2
Impedance of arm (right)	0.8	3.6	6.8	2.6	0.6
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	2.5	-0.4	-1.6
Hair/balding pattern: Pattern 3	0.8	1.2	2.1	1.4	-0.6
Serious illness, injury or assault of a close relative in last 2 years	0.8	1.0	1.9	0.2	-1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	2.1	-1.5	0.6
Medication: Aspirin	0.8	1.0	1.4	-0.8	1.2
Medication: Paracetamol	0.8	1.3	2.0	0.8	-1.4
Fractured/broken bones in last 5 years	0.8	1.0	1.4	0.8	-1.2
Commuting to job workplace: Cycle	0.8	1.0	1.8	1.4	-0.5
Neuroticism (2016)	0.7	1.0	2.0	-1.4	0.3
Hand grip strength (left)	0.7	1.8	3.5	1.9	-0.0
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	1.4	1.2	-0.6
Age when periods started (menarche)	0.7	1.6	2.8	-1.7	0.7
Supplements: Glucosamine	0.7	0.9	1.6	-0.5	1.3
Standing height	0.7	6.6	11.4	1.3	3.4
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	0.8	0.9	0.9
Emphysema/chronic bronchitis	0.7	0.7	1.5	0.0	-1.2
Medication: Allopurinol	0.7	1.0	1.6	-0.6	1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	1.6	0.3	-1.3
Loneliness, isolation	0.7	0.9	1.8	1.3	-0.2
Friendships satisfaction	0.7	0.8	1.2	0.7	1.1
Osteoarthritis (self-reported)	0.7	0.9	1.7	-1.3	-0.2
Illnesses of father: None of the above (group 1)	0.7	0.8	0.9	1.0	-0.9
Hearing aid user	0.7	0.8	1.5	0.2	-1.2
Bipolar Disorder (2018)	0.6	0.9	1.2	-0.8	-1.1
Ovarian Cancer	0.6	0.8	1.0	-1.0	-0.8
LDL Cholesterol	0.6	0.9	1.2	0.8	-1.1
Sensitivity / hurt feelings	0.6	1.0	1.6	-1.2	0.7
Hand grip strength (right)	0.6	1.6	3.1	1.8	0.4
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	1.2	-0.3	1.1
Falls in the last year	0.6	0.9	1.5	-1.2	-0.5
Wheeze or whistling in the chest in last year	0.6	1.0	1.7	-1.3	0.6
Medication: Seretide 50 evohaler	0.6	0.7	1.3	-1.1	-0.2
Pain type(s) experienced in last month: Hip pain	0.6	0.7	1.0	-1.0	0.7
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	1.3	-1.2	-0.2
Impedance of whole body	0.6	2.9	4.5	2.1	1.2
Alzheimer’s Disease (in father)	0.5	0.6	0.9	-1.0	-0.4
Coronary Artery Disease (CAD)	0.5	0.6	0.9	-0.5	1.0
Blood Eosinophil Count	0.5	3.8	6.8	0.9	2.6
Respiratory disease	0.5	1.0	1.5	1.2	-0.8
Lung FEV1/FVC ratio	0.5	2.7	3.1	1.5	-1.8
Vitamin and mineral supplements	0.5	0.7	1.3	-0.0	1.2
Supplements: Zinc	0.5	0.6	1.2	0.0	-1.1
Diabetes (father)	0.5	0.6	0.9	-0.9	0.6
Maternal smoking around birth	0.5	0.7	1.0	-1.0	-0.6
High blood pressure (mother)	0.5	0.7	1.3	-1.1	0.1
Hair/balding pattern: Pattern 2	0.5	0.6	1.0	-1.0	0.5
Qualifications: A levels/AS levels or equivalent	0.5	1.0	1.8	0.6	-1.3
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.1	1.1	-0.2
Gout (self-reported)	0.5	0.6	0.9	-0.6	0.9
Medication for pain relief, constipation, heartburn	0.5	0.8	1.0	0.8	1.0
Suffer from ‘nerves’	0.5	0.8	1.2	-1.1	0.6
Guilty feelings	0.5	0.7	1.3	-0.3	-1.1
Financial situation satisfaction	0.5	0.6	1.2	-1.1	0.2
Commuting to job workplace: Public transport	0.5	0.6	0.8	0.7	0.9
Medication: Blood pressure	0.5	0.9	1.6	-0.5	1.3
Neuroticism (Nagel 2018)	0.4	1.0	1.9	-0.2	1.4
Height	0.4	8.5	13.8	1.8	3.7
Chronotype (morning person)	0.4	0.9	1.6	0.3	1.3
Medication for hormone replacement therapy	0.4	0.4	0.5	-0.7	0.6
Taking other prescription medications	0.4	0.6	0.7	-0.7	0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.4	1.0	1.5	0.7	1.2
Past tobacco smoking	0.4	0.8	1.5	-0.1	1.2
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.0	0.1	-1.0
Headache pain in last month	0.4	0.7	1.3	0.1	-1.1
Medication: Ventolin 100micrograms inhaler	0.4	0.5	0.7	0.5	0.9
Exposure to tobacco smoke outside home	0.4	0.5	0.9	-0.1	1.0
Leg fat mass (right)	0.4	1.7	2.2	-1.5	1.1
Arm predicted mass (right)	0.4	2.2	3.3	-1.0	1.8
Comparative height size at age 10	0.4	2.4	4.4	0.6	2.1
Chest pain or discomfort	0.4	0.6	0.9	-0.9	0.6
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.1	1.0	0.1
Illnesses of father: Heart disease	0.4	0.6	0.8	-0.9	0.7
Long-standing illness, disability or infirmity	0.4	0.6	1.2	-0.1	-1.1
Commuting to job workplace: Walk	0.4	0.5	0.9	1.0	0.1
Osteoporosis (self-reported)	0.4	0.6	1.1	1.0	-0.1
Eye problems/disorders: Glaucoma	0.4	0.4	0.8	-0.9	-0.1
Arm fat-free mass (left)	0.4	1.8	2.4	-1.1	1.6
Age started oral contraceptive pill	0.4	0.5	0.9	0.9	0.2
Ever depressed for a whole week	0.4	0.4	0.8	-0.9	0.2
Pain experienced in last month	0.4	0.7	1.4	1.2	0.2
Leg fat mass (left)	0.4	1.5	1.9	-1.4	1.0
Depressed Affect (Nagel 2018)	0.3	0.7	1.0	1.0	-0.7
Impedance of leg (right)	0.3	1.6	2.4	0.9	1.6
Trunk fat percentage	0.3	1.1	2.2	-0.3	1.5
Townsend deprivation index at recruitment	0.3	0.5	0.9	-0.9	0.3
Relative age voice broke	0.3	0.5	0.9	0.2	1.0
Medication: Levothyroxine sodium	0.3	0.5	1.0	-1.0	-0.1
Body mass index (BMI)	0.3	1.2	2.3	-1.5	-0.0
Impedance of leg (left)	0.3	1.4	1.9	1.0	1.4
Trunk fat mass	0.3	1.3	2.5	-0.2	1.6
Waist circumference	0.3	1.2	1.8	-1.4	0.8
Number of incorrect matches in round	0.3	0.4	0.8	-0.3	0.9
Had other major operations	0.3	0.4	0.8	-0.9	0.3
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	0.7	0.2	-0.9
Alcohol intake versus 10 years previously	0.3	0.5	0.9	1.0	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	1.8	1.4	-0.3
Arm fat mass (right)	0.3	1.2	1.3	-1.1	1.0
Hair/balding pattern: Pattern 4	0.3	0.8	1.4	-0.5	1.2
Chronic bronchitis/emphysema (mother)	0.3	0.4	0.4	-0.6	-0.6
Leg fat percentage (right)	0.3	1.1	2.0	-1.4	0.5
Arm fat-free mass (right)	0.3	1.4	2.3	-0.8	1.5
Health satisfaction	0.3	0.4	0.8	-0.2	0.9
Eye problems/disorders: None of the above	0.3	0.3	0.5	0.7	-0.4
Whole body fat mass	0.3	1.3	2.1	-0.8	1.4
Supplements: Fish oil (including cod liver oil)	0.3	0.5	0.9	-0.9	-0.1
Risk taking	0.3	0.5	0.9	-0.1	-1.0
Supplements: Calcium	0.3	0.3	0.4	0.6	-0.6
Schizophrenia (2018)	0.2	0.3	0.5	0.4	0.7
Reaction Time	0.2	0.3	0.5	0.7	-0.2
Schizophrenia (2014)	0.2	0.3	0.3	0.6	0.6
Blood Platelet Count	0.2	1.8	3.3	-0.5	-1.8
Hypothyroidism (self reported)	0.2	0.5	0.8	-0.9	0.4
Tanning	0.2	2.0	3.9	-2.0	0.2
Average weekly spirits intake	0.2	0.2	0.4	-0.7	-0.3
Hearing difficulty/problems: Yes	0.2	0.2	0.5	-0.7	0.0
Pack years adult smoking proportion	0.2	0.3	0.5	-0.7	0.2
Leg fat-free mass (left)	0.2	0.9	1.6	-0.4	1.3
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	0.3	-0.5	-0.6
Had menopause	0.2	0.2	0.4	-0.3	-0.6
Forced vital capacity (FVC)	0.2	0.9	1.1	1.0	0.8
Financial difficulties in last 2 years	0.2	0.2	0.4	-0.6	0.3
Medication: Ramipril	0.2	0.3	0.4	-0.7	0.4
Weight	0.2	1.2	1.8	-0.7	1.3
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	1.4	1.2	0.2
Trunk predicted mass	0.2	1.0	1.7	-0.5	1.3
Forced vital capacity (FVC), Best measure	0.2	0.8	1.6	1.3	0.3
Body fat percentage	0.2	0.8	1.2	-0.7	1.1
Shortness of breath walking on level ground	0.2	0.2	0.3	0.6	-0.2
Medication: Ibuprofen	0.2	0.2	0.3	0.3	-0.5
Knee pain experienced in last month	0.2	0.3	0.6	-0.2	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	0.5	-0.7	-0.0
Smoking status: Previous	0.2	0.3	0.4	0.5	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	0.5	0.7	0.6
Average weekly red wine intake	0.2	0.3	0.6	0.8	-0.1
Mood swings	0.2	0.3	0.6	0.3	-0.7
Qualifications: nursing, teaching	0.2	0.4	0.7	0.9	0.0
Eye problems/disorders: Cataract	0.2	0.3	0.5	0.7	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.5	0.2	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.3	0.4	0.6	-0.5
Whole body water mass	0.2	1.2	2.0	-0.6	1.4
Arm fat mass (left)	0.2	1.0	1.2	-0.9	1.1
Miserableness	0.2	0.3	0.5	-0.4	0.7
Wears glasses or contact lenses	0.2	0.2	0.5	0.2	0.7
Mother’s age at death	0.2	0.3	0.4	0.7	0.4
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.4	0.6	-0.0
Alcohol drinker status: Never	0.2	0.2	0.3	0.5	-0.4
Basal metabolic rate	0.2	1.0	1.7	-0.6	1.3
Leg fat percentage (left)	0.2	0.9	1.7	-1.3	0.3
Pack years of smoking	0.2	0.3	0.6	-0.7	0.0
Arm predicted mass (left)	0.2	1.1	1.4	-0.9	1.2
Verbal and Numeric Reasoning (VNR)	0.1	0.3	0.3	0.5	-0.5
Prostate Cancer	0.1	0.1	0.2	-0.0	0.5
Hair Pigment	0.1	1.7	2.4	1.1	-1.5
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.3	0.3	-0.5
Relative age of first facial hair	0.1	0.3	0.5	-0.2	0.7
Fed-up feelings	0.1	0.3	0.4	-0.6	-0.4
Qualifications: CSEs or equivalent	0.1	0.2	0.3	-0.2	-0.5
Leg predicted mass (left)	0.1	0.7	1.3	-0.3	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.1	0.1	-0.3	-0.3
Hearing difficulty/problems with background noise	0.1	0.1	0.3	0.5	0.2
Mouth/teeth dental problems	0.1	0.1	0.2	0.3	0.5
Medication: Simvastatin	0.1	0.1	0.2	-0.1	0.4
Fluid intelligence score	0.1	0.2	0.2	-0.5	-0.4
Arm fat percentage (right)	0.1	0.3	0.6	-0.8	0.3
Trunk fat-free mass	0.1	0.9	1.5	-0.5	1.2
Noisy workplace	0.1	0.1	0.1	-0.4	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.2	0.1	-0.4
Breastfed as a baby	0.1	0.1	0.2	0.2	0.4
Loud music exposure frequency	0.1	0.1	0.1	-0.4	-0.2
Glaucoma (self-reported)	0.1	0.1	0.2	-0.5	-0.0
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.4	-0.2	-0.7
Mean time to correctly identify matches	0.1	0.3	0.4	0.4	-0.6
Alcohol intake frequency.	0.1	0.3	0.7	-0.0	-0.8
Supplements: Vitamin C	0.1	0.1	0.1	-0.2	0.3
Illnesses of siblings: Diabetes	0.1	0.2	0.2	-0.5	-0.3
Whole body fat-free mass	0.1	0.8	1.5	-0.5	1.2
Leg fat-free mass (right)	0.1	0.5	0.9	-0.3	0.9
Arm fat percentage (left)	0.1	0.3	0.3	-0.5	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.2	0.5	-0.0
Leg predicted mass (right)	0.1	0.6	1.0	-0.4	1.0
Illnesses of father: High blood pressure	0.1	0.2	0.3	0.0	-0.6
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.2	0.5	0.1
Cholesterol lowering medication	0.1	0.2	0.2	0.4	0.5
Bipolar Disorder or Schizophrenia	0.0	0.1	0.2	-0.4	-0.0
Alzheimer’s Disease (including proxy)	0.0	0.0	0.0	-0.1	0.2
Age at First Birth	0.0	0.0	0.0	-0.1	-0.2
Body Mass Index (BMI) (2010)	0.0	0.1	0.1	-0.3	-0.1
Triglycerides	0.0	0.0	0.0	0.1	0.1
BMI	0.0	0.3	0.4	-0.6	0.5
Lung FVC	0.0	0.1	0.1	-0.4	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.0	0.0	0.0	0.2	-0.1
Alcohol usually taken with meals	0.0	0.0	0.1	-0.1	0.3
Hip circumference	0.0	0.1	0.1	-0.2	-0.3
Happiness	0.0	0.0	0.0	-0.1	0.0
Mouth/teeth dental problems: Dentures	0.0	0.0	0.1	-0.1	-0.3
Heart disease (mother)	0.0	0.0	0.1	0.0	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.0	0.0	0.0	0.1
Back pain experienced in last month	0.0	0.1	0.1	0.2	-0.3
Breast cancer (self-reported)	0.0	0.1	0.1	-0.2	0.2
Number of self-reported non-cancer illnesses	0.0	0.1	0.1	-0.3	0.0
Average weekly champagne plus white wine intake	0.0	0.0	0.0	0.2	-0.0
High cholesterol (Self-reported)	0.0	0.1	0.1	0.1	-0.3

Hub : Genes

UQCRC1

Models

Trait associations