Hub : Genes

UQCRC1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Artery Coronary 0.7930 0.0510 3.1e-05 0.019 NA 0.014 NA -0.007 0.075 NA 0.11 NA 0.65
2 GTEx Heart Left Ventricle 0.0652 0.0371 9.5e-03 -0.005 NA -0.003 NA -0.005 0.690 NA 0.54 NA 0.72

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.6 0.9 1.2 -0.8 -1.1
Bipolar Disorder or Schizophrenia 0.0 0.1 0.2 -0.4 -0.0
Depressed Affect (Nagel 2018) 0.3 0.7 1.0 1.0 -0.7
Depression (Nagel 2018) 1.7 2.5 3.1 1.8 -1.4
Intelligence (Savage-Jansen 2018) 1.4 4.4 5.4 2.3 -1.8
Neuroticism (Nagel 2018) 0.4 1.0 1.9 -0.2 1.4
Schizophrenia (2018) 0.2 0.3 0.5 0.4 0.7
Schizophrenia vs Biploar Disorder 0.9 1.2 1.6 0.9 1.3
Worry (Nagel 2018) 1.5 3.2 5.2 -1.1 2.3
Alzheimer’s Disease (in mother) 0.9 1.0 2.0 1.4 -0.2
Alzheimer’s Disease (in father) 0.5 0.6 0.9 -1.0 -0.4
Alzheimer’s Disease (including proxy) 0.0 0.0 0.0 -0.1 0.2
Crohns Disease (2017) 3.3 7.2 9.4 3.1 -2.2
Irritable Bowel Disease (IBD) 4.3 10.1 10.2 3.2 -3.2
Ulcerative Colitis (UC) 2.8 5.2 5.9 2.1 -2.4
Major Depression (MDD) 2.3 2.8 4.0 -2.0 1.2
Reaction Time 0.2 0.3 0.5 0.7 -0.2
Verbal and Numeric Reasoning (VNR) 0.1 0.3 0.3 0.5 -0.5
Breast Cancer 1.8 4.3 7.6 -1.0 -2.8
Ovarian Cancer 0.6 0.8 1.0 -1.0 -0.8
Prostate Cancer 0.1 0.1 0.2 -0.0 0.5
Age at First Birth 0.0 0.0 0.0 -0.1 -0.2
Bipolar Disorder (2011) 2.0 1.9 3.2 0.8 -1.8
Body Mass Index (BMI) (2010) 0.0 0.1 0.1 -0.3 -0.1
Coronary Artery Disease (CAD) 0.5 0.6 0.9 -0.5 1.0
Crohns Disease (2012) 4.8 7.7 8.5 2.6 -2.9
Mean Putamen Volume 3.7 4.3 6.5 1.4 -2.5
Fasting Glucose 1.2 1.4 2.6 -0.5 1.6
HbA1C 1.3 1.5 2.8 -1.7 0.4
HDL Cholesterol 1.5 2.5 3.9 1.0 -2.0
LDL Cholesterol 0.6 0.9 1.2 0.8 -1.1
Lupus 1.3 1.9 3.4 0.7 -1.9
Neuroticism (2016) 0.7 1.0 2.0 -1.4 0.3
Primary Biliary Cirrhosis 2.6 3.7 6.7 0.9 -2.6
Rheumatoid Arthritis 2.1 2.9 3.4 1.6 -1.9
Schizophrenia (2014) 0.2 0.3 0.3 0.6 0.6
Triglycerides 0.0 0.0 0.0 0.1 0.1
Type 2 Diabetes (T2D) (2012) 5.5 6.3 11.7 -1.0 3.4
Ulcerative Colitis 3.2 4.6 7.1 1.4 -2.7
Blood Eosinophil Count 0.5 3.8 6.8 0.9 2.6
Blood Platelet Count 0.2 1.8 3.3 -0.5 -1.8
Blood Red Count 0.8 8.1 15.4 0.9 3.9
Blood White Count 2.7 19.7 25.5 -3.7 5.0
Heel T-Score 1.8 14.5 28.8 -0.5 5.4
BMI 0.0 0.3 0.4 -0.6 0.5
Height 0.4 8.5 13.8 1.8 3.7
Waist Hip Ratio (WHR) 1.3 5.8 8.0 -1.9 2.8
Systolic Blood Pressure 2.6 12.8 18.8 -2.6 4.3
Smoking Status 1.8 4.3 8.4 0.4 -2.9
Allergy or Eczema 1.1 2.9 4.4 2.1 -1.2
Cardiovascular Disease 1.8 6.0 9.6 -1.6 3.1
Hypothyroidism (self reported) 0.2 0.5 0.8 -0.9 0.4
Respiratory disease 0.5 1.0 1.5 1.2 -0.8
Type 2 Diabetes (T2D) (2018) 1.7 3.3 3.7 -1.9 1.7
Lung FEV1/FVC ratio 0.5 2.7 3.1 1.5 -1.8
Lung FVC 0.0 0.1 0.1 -0.4 0.1
Neuroticism 1.9 4.5 4.5 -2.1 2.1
Chronotype (morning person) 0.4 0.9 1.6 0.3 1.3
Hair Pigment 0.1 1.7 2.4 1.1 -1.5
Tanning 0.2 2.0 3.9 -2.0 0.2
Hand grip strength (left) 0.7 1.8 3.5 1.9 -0.0
Number of treatments/medications taken 1.4 2.5 4.5 -0.7 2.1
Average weekly spirits intake 0.2 0.2 0.4 -0.7 -0.3
Sensitivity / hurt feelings 0.6 1.0 1.6 -1.2 0.7
Frequency of depressed mood in last 2 weeks 0.1 0.2 0.3 0.3 -0.5
Hearing difficulty/problems: Yes 0.2 0.2 0.5 -0.7 0.0
Relative age of first facial hair 0.1 0.3 0.5 -0.2 0.7
Other serious medical condition/disability diagnosed by doctor 0.7 0.9 1.4 1.2 -0.6
Ever used hormone-replacement therapy (HRT) 0.8 1.0 1.6 -0.7 1.3
Ever had hysterectomy (womb removed) 0.8 0.8 1.7 -0.1 1.3
Systolic blood pressure, automated reading 1.5 4.4 5.3 -2.3 1.9
Eye problems/disorders: Diabetes related eye disease 2.0 2.2 3.7 -1.9 0.8
Angina 1.0 1.3 1.8 -1.3 0.9
Medication for hormone replacement therapy 0.4 0.4 0.5 -0.7 0.6
Vitamin and mineral supplements 0.5 0.7 1.3 -0.0 1.2
Supplements: Zinc 0.5 0.6 1.2 0.0 -1.1
Medication: Co-codamol 1.8 2.1 3.7 -1.9 0.7
Medication: Metformin 4.2 5.9 8.9 -3.0 1.7
Diabetes (father) 0.5 0.6 0.9 -0.9 0.6
Diabetes (mother) 4.6 5.9 7.0 -2.6 2.2
Severe depression (siblings) 1.4 1.5 1.6 -1.2 -1.2
Pack years adult smoking proportion 0.2 0.3 0.5 -0.7 0.2
Impedance of leg (right) 0.3 1.6 2.4 0.9 1.6
Leg fat-free mass (left) 0.2 0.9 1.6 -0.4 1.3
Trunk fat percentage 0.3 1.1 2.2 -0.3 1.5
Hand grip strength (right) 0.6 1.6 3.1 1.8 0.4
Townsend deprivation index at recruitment 0.3 0.5 0.9 -0.9 0.3
Current tobacco smoking 1.3 2.1 4.2 0.3 -2.0
Average weekly fortified wine intake 0.8 1.0 1.9 1.4 -0.3
Maternal smoking around birth 0.5 0.7 1.0 -1.0 -0.6
Fed-up feelings 0.1 0.3 0.4 -0.6 -0.4
Frequency of unenthusiasm / disinterest in last 2 weeks 0.0 0.0 0.0 0.2 -0.1
Relative age voice broke 0.3 0.5 0.9 0.2 1.0
Taking other prescription medications 0.4 0.6 0.7 -0.7 0.9
Age when periods started (menarche) 0.7 1.6 2.8 -1.7 0.7
Bilateral oophorectomy (both ovaries removed) 1.3 1.5 1.7 -1.3 1.1
Heel bone mineral density (BMD) T-score, automated (left) 0.4 1.0 1.5 0.7 1.2
Tinnitus: Yes, but not now, but have in the past 0.6 0.7 1.2 -0.3 1.1
Qualifications: CSEs or equivalent 0.1 0.2 0.3 -0.2 -0.5
Serious illness, injury or assault to yourself 0.9 1.1 2.1 0.2 -1.5
High blood pressure 0.8 2.4 3.5 -1.1 1.9
Hayfever, allergic rhinitis or eczema 0.8 1.8 3.2 1.8 -0.6
Multivitamins +/- minerals 0.8 1.0 2.1 -0.0 -1.4
Stomach or abdominal pain in last month 1.5 1.9 3.7 -1.9 0.3
Supplements: Glucosamine 0.7 0.9 1.6 -0.5 1.3
Diverticular disease/diverticulitis (self-reported) 0.2 0.3 0.3 -0.5 -0.6
Medication: Atenolol 3.1 3.9 5.8 -1.4 2.4
Medication: Levothyroxine sodium 0.3 0.5 1.0 -1.0 -0.1
Sitting height 1.6 11.4 22.8 -0.3 4.8
Chronic bronchitis/emphysema (father) 1.3 1.5 2.7 -1.7 0.4
High blood pressure (mother) 0.5 0.7 1.3 -1.1 0.1
Body mass index (BMI) 0.3 1.2 2.3 -1.5 -0.0
Impedance of leg (left) 0.3 1.4 1.9 1.0 1.4
Leg predicted mass (left) 0.1 0.7 1.3 -0.3 1.1
Trunk fat mass 0.3 1.3 2.5 -0.2 1.6
Waist circumference 0.3 1.2 1.8 -1.4 0.8
Number of incorrect matches in round 0.3 0.4 0.8 -0.3 0.9
Past tobacco smoking 0.4 0.8 1.5 -0.1 1.2
Alcohol usually taken with meals 0.0 0.0 0.1 -0.1 0.3
Nervous feelings 0.9 1.6 3.0 -0.5 1.7
Frequency of tenseness / restlessness in last 2 weeks 0.1 0.1 0.1 -0.3 -0.3
Hearing difficulty/problems with background noise 0.1 0.1 0.3 0.5 0.2
Hair/balding pattern: Pattern 2 0.5 0.6 1.0 -1.0 0.5
Had menopause 0.2 0.2 0.4 -0.3 -0.6
Had other major operations 0.3 0.4 0.8 -0.9 0.3
Forced vital capacity (FVC) 0.2 0.9 1.1 1.0 0.8
Heel bone mineral density (BMD) T-score, automated (right) 1.1 2.6 4.6 0.7 2.2
Ever unenthusiastic/disinterested for a whole week 0.3 0.4 0.7 0.2 -0.9
Qualifications: None of the above 0.8 1.7 3.4 -1.8 0.2
Financial difficulties in last 2 years 0.2 0.2 0.4 -0.6 0.3
Mouth/teeth dental problems 0.1 0.1 0.2 0.3 0.5
Heart attack 1.4 1.8 3.0 -1.7 0.8
Allergy 3.0 7.0 9.1 -3.0 2.2
Pain all over the body in last month 1.4 1.5 2.3 -1.5 -0.8
Diabetes (self-reported) 1.9 3.0 5.5 -2.4 0.7
Hayfever/allergic rhinitis (self-reported) 1.1 1.5 2.8 1.7 -0.3
Medication: Ramipril 0.2 0.3 0.4 -0.7 0.4
Medication: Simvastatin 0.1 0.1 0.2 -0.1 0.4
Fluid intelligence score 0.1 0.2 0.2 -0.5 -0.4
Illnesses of siblings 2.3 3.2 6.2 2.5 0.3
Neuroticism score 1.4 3.0 3.1 -1.7 1.8
Weight 0.2 1.2 1.8 -0.7 1.3
Impedance of arm (right) 0.8 3.6 6.8 2.6 0.6
Arm fat percentage (right) 0.1 0.3 0.6 -0.8 0.3
Trunk fat-free mass 0.1 0.9 1.5 -0.5 1.2
Hip circumference 0.0 0.1 0.1 -0.2 -0.3
Time employed in main current job 1.7 1.9 3.8 0.2 -1.9
Alcohol intake versus 10 years previously 0.3 0.5 0.9 1.0 0.1
Father’s age at death 6.5 8.7 11.9 2.4 -3.5
Worrier / anxious feelings 1.8 3.5 4.0 -1.7 2.0
Frequency of tiredness / lethargy in last 2 weeks 0.8 1.3 2.5 -0.4 -1.6
Falls in the last year 0.6 0.9 1.5 -1.2 -0.5
Hair/balding pattern: Pattern 3 0.8 1.2 2.1 1.4 -0.6
Number of live births 1.9 2.7 4.1 -2.0 1.2
Forced expiratory volume in 1-second (FEV1) 0.2 0.7 1.4 1.2 0.2
Pulse rate 1.8 3.0 5.6 -0.6 2.4
Happiness 0.0 0.0 0.0 -0.1 0.0
Noisy workplace 0.1 0.1 0.1 -0.4 0.1
Qualifications: A levels/AS levels or equivalent 0.5 1.0 1.8 0.6 -1.3
Serious illness, injury or assault of a close relative in last 2 years 0.8 1.0 1.9 0.2 -1.4
Mouth/teeth dental problems: Dentures 0.0 0.0 0.1 -0.1 -0.3
Asthma 0.9 1.8 2.3 1.5 -1.2
Medication: Ibuprofen (e.g. Nurofen) 0.1 0.1 0.2 0.1 -0.4
Medication: Cholesterol lowering 2.0 3.1 4.7 -1.3 2.2
Depression (self-reported) 2.1 2.6 4.7 0.6 -2.2
Medication: Lansoprazole 3.1 3.5 4.1 -1.7 2.0
Prospective memory result 1.0 1.3 2.0 1.4 0.8
Lung cancer (father) 1.9 2.2 3.5 0.9 -1.9
Illnesses of mother 1.1 1.3 1.9 1.4 -0.9
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 1.0 1.8 1.4 -0.3
Pulse wave Arterial Stiffness index 1.8 2.2 2.6 -1.3 1.6
Impedance of arm (left) 0.9 4.2 7.7 2.8 0.8
Arm fat mass (right) 0.3 1.2 1.3 -1.1 1.0
Trunk predicted mass 0.2 1.0 1.7 -0.5 1.3
Standing height 0.7 6.6 11.4 1.3 3.4
Length of working week for main job 1.8 2.0 4.0 -2.0 -0.3
Exposure to tobacco smoke at home 1.1 1.3 2.2 -0.6 1.5
Breastfed as a baby 0.1 0.1 0.2 0.2 0.4
Tense / ‘highly strung’ 2.2 3.7 4.7 -1.6 2.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.8 1.2 2.1 -1.5 0.6
Hair/balding pattern: Pattern 4 0.3 0.8 1.4 -0.5 1.2
Birth weight of first child 2.1 3.8 7.5 0.3 -2.7
Peak expiratory flow (PEF) 0.9 2.2 4.0 0.6 -2.0
Pulse wave reflection index 1.9 2.4 4.8 -2.2 -0.1
Ever highly irritable/argumentative for 2 days 0.5 0.6 1.1 1.1 -0.2
Loud music exposure frequency 0.1 0.1 0.1 -0.4 -0.2
Qualifications: O levels/GCSEs or equivalent 1.1 1.8 2.4 1.1 -1.5
Mouth/teeth dental problems: Bleeding gums 0.4 0.5 1.0 0.1 -1.0
Blood clot in the leg (DVT) 1.8 2.3 4.1 0.7 -2.0
Medication: Paracetamol 1.1 1.7 3.4 0.4 -1.8
Headache pain in last month 0.4 0.7 1.3 0.1 -1.1
Medication for cholesterol, blood pressure or diabetes 4.9 8.2 12.0 2.1 -3.5
Glaucoma (self-reported) 0.1 0.1 0.2 -0.5 -0.0
Gout (self-reported) 0.5 0.6 0.9 -0.6 0.9
Hypothyroidism/myxoedema (self-reported) 0.1 0.2 0.4 -0.2 -0.7
Medication: Amlodipine 1.6 2.2 2.3 -1.4 1.5
Medication: Ventolin 100micrograms inhaler 0.4 0.5 0.7 0.5 0.9
Birth weight 2.3 5.1 7.1 1.8 -2.7
Chronic bronchitis/emphysema (mother) 0.3 0.4 0.4 -0.6 -0.6
High blood pressure (siblings) 2.4 3.4 5.8 -2.4 1.0
Forced vital capacity (FVC), Best measure 0.2 0.8 1.6 1.3 0.3
Body fat percentage 0.2 0.8 1.2 -0.7 1.1
Leg fat percentage (right) 0.3 1.1 2.0 -1.4 0.5
Arm fat-free mass (right) 0.3 1.4 2.3 -0.8 1.5
Exposure to tobacco smoke outside home 0.4 0.5 0.9 -0.1 1.0
Comparative body size at age 10 2.8 7.7 13.9 1.2 -3.7
Number of full brothers 1.5 1.9 2.6 -1.6 -1.1
Worry too long after embarrassment 2.0 3.3 4.5 -1.4 2.1
Seen a psychiatrist for nerves, anxiety, tension or depression 1.3 1.6 2.0 1.1 -1.4
Wheeze or whistling in the chest in last year 0.6 1.0 1.7 -1.3 0.6
Number of children fathered 1.3 1.5 2.9 -1.7 -0.2
Reason for reducing amount of alcohol drunk: Health precaution 0.7 0.8 0.8 0.9 0.9
Age at first live birth 1.2 2.1 4.0 2.0 -0.5
Pulse wave peak to peak time 1.4 1.7 1.7 1.3 -1.3
Health satisfaction 0.3 0.4 0.8 -0.2 0.9
Shortness of breath walking on level ground 0.2 0.2 0.3 0.6 -0.2
Qualifications: College or University degree 1.5 4.7 7.9 2.8 -1.2
Eye problems/disorders: None of the above 0.3 0.3 0.5 0.7 -0.4
Mouth/teeth dental problems: Loose teeth 4.0 4.8 8.3 -2.9 1.1
Emphysema/chronic bronchitis 0.7 0.7 1.5 0.0 -1.2
Medication for pain relief, constipation, heartburn 0.5 0.8 1.0 0.8 1.0
Neck or shoulder pain in last month 1.6 2.3 4.5 -2.1 -0.2
Medication: Blood pressure 4.4 7.8 10.1 -2.3 3.2
Angina (self-reported) 1.3 1.7 2.6 -1.6 0.9
Migraine (self-reported) 4.0 5.0 9.9 -0.2 -3.1
Medication: Ibuprofen 0.2 0.2 0.3 0.3 -0.5
Medication: Allopurinol 0.7 1.0 1.6 -0.6 1.3
Medication: Omeprazole 1.1 1.3 2.5 -1.6 0.1
Medication: Seretide 50 evohaler 0.6 0.7 1.3 -1.1 -0.2
Mean time to correctly identify matches 0.1 0.3 0.4 0.4 -0.6
Heart disease (mother) 0.0 0.0 0.1 0.0 0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.7 0.8 1.6 0.3 -1.3
Whole body fat mass 0.3 1.3 2.1 -0.8 1.4
Leg fat mass (right) 0.4 1.7 2.2 -1.5 1.1
Arm predicted mass (right) 0.4 2.2 3.3 -1.0 1.8
Pulse rate, automated reading 5.4 17.4 34.1 -0.8 5.8
Alcohol intake frequency. 0.1 0.3 0.7 -0.0 -0.8
Comparative height size at age 10 0.4 2.4 4.4 0.6 2.1
Number of full sisters 1.1 1.3 1.7 -1.3 -0.9
Suffer from ‘nerves’ 0.5 0.8 1.2 -1.1 0.6
Overall health rating 0.9 1.9 3.7 -1.9 0.4
Chest pain or discomfort 0.4 0.6 0.9 -0.9 0.6
Had major operations 2.3 2.7 2.7 -1.6 1.6
Age at last live birth 1.3 1.9 3.7 1.9 -0.5
Family relationship satisfaction 1.3 1.6 2.5 -0.8 1.6
Leg pain on walking 1.1 1.4 2.1 1.4 -0.9
Qualifications: NVQ or HND or HNC or equivalent 0.0 0.0 0.0 0.0 0.1
Commuting to job workplace: Car/motor vehicle 1.5 1.7 2.8 -1.7 -0.8
Illness, injury, bereavement, stress in last 2 years 0.4 0.5 1.1 1.0 0.1
Medication: Aspirin 2.0 2.6 3.0 -1.7 1.5
Supplements: Vitamin C 0.1 0.1 0.1 -0.2 0.3
Knee pain experienced in last month 0.2 0.3 0.6 -0.2 -0.8
Hypertension (Self-reported) 1.0 2.7 4.1 -1.2 2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.2 0.3 0.5 -0.7 -0.0
Illnesses of father: Heart disease 0.4 0.6 0.8 -0.9 0.7
Illnesses of siblings: Diabetes 0.1 0.2 0.2 -0.5 -0.3
Smoking status: Previous 0.2 0.3 0.4 0.5 -0.6
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.4 0.5 0.7 0.6
Whole body fat-free mass 0.1 0.8 1.5 -0.5 1.2
Leg fat-free mass (right) 0.1 0.5 0.9 -0.3 0.9
Arm fat percentage (left) 0.1 0.3 0.3 -0.5 0.5
Average weekly red wine intake 0.2 0.3 0.6 0.8 -0.1
Handedness (chirality/laterality): Left-handed 1.5 1.8 3.5 -0.2 1.9
Mood swings 0.2 0.3 0.6 0.3 -0.7
Loneliness, isolation 0.7 0.9 1.8 1.3 -0.2
Long-standing illness, disability or infirmity 0.4 0.6 1.2 -0.1 -1.1
Ever had bowel cancer screening 1.9 2.2 4.2 0.4 -2.0
Diabetes diagnosed by doctor 1.9 3.2 4.7 -2.2 1.3
Ever had stillbirth, spontaneous miscarriage or termination 0.1 0.1 0.2 0.5 -0.0
Friendships satisfaction 0.7 0.8 1.2 0.7 1.1
Qualifications: nursing, teaching 0.2 0.4 0.7 0.9 0.0
Commuting to job workplace: Walk 0.4 0.5 0.9 1.0 0.1
Eye problems/disorders: Cataract 0.2 0.3 0.5 0.7 -0.2
Mouth/teeth dental problems: Mouth ulcers 0.2 0.3 0.5 0.2 -0.7
Medication for cholesterol 1.1 1.7 3.4 0.1 -1.9
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.3 1.5 3.1 -1.8 0.2
Back pain experienced in last month 0.0 0.1 0.1 0.2 -0.3
Mineral and other dietary supplements 1.1 1.5 2.9 1.7 -0.4
Breast cancer (self-reported) 0.0 0.1 0.1 -0.2 0.2
Asthma (self-reported) 1.0 1.9 2.9 1.7 -1.0
Osteoporosis (self-reported) 0.4 0.6 1.1 1.0 -0.1
Osteoarthritis (self-reported) 0.7 0.9 1.7 -1.3 -0.2
Medication: Aspirin 0.8 1.0 1.4 -0.8 1.2
Medication: Gliclazide 1.0 1.1 2.0 -1.4 0.5
Illnesses of father: None of the above (group 1) 0.7 0.8 0.9 1.0 -0.9
Smoking status: Current 0.9 1.4 2.8 0.2 -1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.3 0.4 0.6 -0.5
Whole body water mass 0.2 1.2 2.0 -0.6 1.4
Leg predicted mass (right) 0.1 0.6 1.0 -0.4 1.0
Arm fat mass (left) 0.2 1.0 1.2 -0.9 1.1
Number of self-reported non-cancer illnesses 0.0 0.1 0.1 -0.3 0.0
Average weekly champagne plus white wine intake 0.0 0.0 0.0 0.2 -0.0
Miserableness 0.2 0.3 0.5 -0.4 0.7
Guilty feelings 0.5 0.7 1.3 -0.3 -1.1
Wears glasses or contact lenses 0.2 0.2 0.5 0.2 0.7
Ever taken oral contraceptive pill 2.0 2.3 3.7 -0.9 1.9
Hearing aid user 0.7 0.8 1.5 0.2 -1.2
Mother’s age at death 0.2 0.3 0.4 0.7 0.4
Financial situation satisfaction 0.5 0.6 1.2 -1.1 0.2
Tinnitus: Yes, now most or all of the time 0.2 0.2 0.4 0.6 -0.0
Commuting to job workplace: Public transport 0.5 0.6 0.8 0.7 0.9
Eye problems/disorders: Glaucoma 0.4 0.4 0.8 -0.9 -0.1
Medication: Blood pressure 0.5 0.9 1.6 -0.5 1.3
Pain type(s) experienced in last month: Hip pain 0.6 0.7 1.0 -1.0 0.7
Supplements: Fish oil (including cod liver oil) 0.3 0.5 0.9 -0.9 -0.1
High cholesterol (Self-reported) 0.0 0.1 0.1 0.1 -0.3
Medication: Bendroflumethiazide 1.6 2.5 4.1 -0.9 2.0
Medication: Paracetamol 0.8 1.3 2.0 0.8 -1.4
Medication: Lisinopril 1.4 1.8 1.9 -1.4 1.3
Medication: Atorvastatin 1.2 1.4 2.0 -1.4 0.9
Illnesses of father: High blood pressure 0.1 0.2 0.3 0.0 -0.6
Alcohol drinker status: Never 0.2 0.2 0.3 0.5 -0.4
Ever smoked 1.0 1.7 3.1 0.6 -1.8
Basal metabolic rate 0.2 1.0 1.7 -0.6 1.3
Leg fat percentage (left) 0.2 0.9 1.7 -1.3 0.3
Arm fat-free mass (left) 0.4 1.8 2.4 -1.1 1.6
Number of operations (self-reported) 2.0 3.0 5.5 -2.3 0.7
Average weekly beer plus cider intake 1.1 1.6 3.0 -0.4 1.7
Irritability 1.3 2.3 4.5 -2.1 -0.3
Risk taking 0.3 0.5 0.9 -0.1 -1.0
Ever had prostate specific antigen (PSA) test 0.1 0.1 0.2 0.5 0.1
Fractured/broken bones in last 5 years 0.8 1.0 1.4 0.8 -1.2
Age started oral contraceptive pill 0.4 0.5 0.9 0.9 0.2
Diastolic blood pressure, automated reading 2.9 8.8 12.4 -2.3 3.5
Ever depressed for a whole week 0.4 0.4 0.8 -0.9 0.2
Unable to work because of sickness or disability 1.5 1.9 3.5 -0.6 -1.9
Commuting to job workplace: Cycle 0.8 1.0 1.8 1.4 -0.5
Myopia 1.7 2.4 4.5 2.1 -0.6
Vascular/heart problems diagnosed by doctor 1.2 3.3 4.5 1.4 -2.1
Cholesterol lowering medication 0.1 0.2 0.2 0.4 0.5
Medication: Omeprazole (e.g. Zanprol) 0.6 0.7 1.3 -1.2 -0.2
Pain experienced in last month 0.4 0.7 1.4 1.2 0.2
Supplements: Calcium 0.3 0.3 0.4 0.6 -0.6
Basal cell carcinoma (self-reported) 1.4 1.6 1.7 1.2 -1.3
Heart attack/myocardial infarction (self-reported) 1.4 1.8 3.0 -1.7 0.8
Deep venous thrombosis (DVT) (self-reported) 2.1 2.6 4.7 0.8 -2.2
Heart disease (siblings) 2.5 3.1 6.0 -2.4 0.5
Alcohol drinker status: Previous 1.1 1.2 2.1 -1.4 -0.6
Pack years of smoking 0.2 0.3 0.6 -0.7 0.0
Impedance of whole body 0.6 2.9 4.5 2.1 1.2
Leg fat mass (left) 0.4 1.5 1.9 -1.4 1.0
Arm predicted mass (left) 0.2 1.1 1.4 -0.9 1.2