Hub : Genes

UQCRH

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1450	0.0390	3.7e-07	0.119	0.073	0.119	0.115	0.118	2.4e-14	3.6e-09	3.0e-14	8.3e-14	3.5e-14
2	METSIM	Adipose	0.0821	0.0304	2.1e-03	0.035	0.022	0.033	0.029	0.029	5.1e-06	2.6e-04	9.8e-06	3.0e-05	2.8e-05
3	NTR	Blood	0.0992	0.0244	8.6e-11	0.049	0.041	0.043	0.041	0.049	1.2e-15	3.6e-13	1.0e-13	3.8e-13	1.4e-15
4	ROSMAP	Brain Pre-frontal Cortex	0.3524	0.0512	0.0e+00	0.234	0.226	0.239	0.232	0.245	1.3e-29	1.3e-28	2.2e-30	2.1e-29	3.8e-31
5	TCGA	Breast Invasive Carcinoma	0.0607	0.0245	3.5e-07	0.034	0.038	0.036	NA	0.029	1.1e-07	2.2e-08	5.0e-08	NA	9.9e-07
6	TCGA	Liver Hepatocellular Carcinoma	0.1450	0.0750	7.6e-03	0.049	0.013	0.014	NA	0.036	2.5e-03	7.9e-02	7.2e-02	NA	8.5e-03
7	TCGA	Prostate Adenocarcinoma	0.0620	0.0384	4.7e-03	0.008	0.010	0.000	NA	0.004	4.3e-02	2.9e-02	3.2e-01	NA	1.0e-01
8	TCGA	Thyroid Carcinoma	0.0480	0.0260	4.4e-03	0.032	0.030	0.028	NA	0.025	4.4e-04	6.0e-04	8.0e-04	NA	1.5e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.3	0.5	2.8	-0.2	0.7	0.4	-0.3	-0.1	-0.1	1.7	-0.2
Bipolar Disorder or Schizophrenia	0.1	0.3	1.7	0.2	0.5	-0.1	0.1	0.1	0.2	1.3	0.5
Depressed Affect (Nagel 2018)	0.3	0.7	1.6	0.7	-0.0	-0.8	0.5	0.8	1.3	1.3	0.3
Depression (Nagel 2018)	0.2	0.2	1.2	-0.2	-1.1	0.5	-0.5	-0.3	-0.3	0.3	0.2
Intelligence (Savage-Jansen 2018)	0.5	1.7	2.5	1.2	1.0	-1.4	1.4	1.5	0.9	1.2	1.6
Neuroticism (Nagel 2018)	0.0	0.1	0.4	-0.1	-0.6	0.1	-0.2	-0.0	0.2	0.1	0.3
Schizophrenia (2018)	0.1	0.3	0.8	0.5	0.5	-0.6	0.4	0.2	0.3	0.3	0.9
Schizophrenia vs Biploar Disorder	0.9	1.2	2.8	-0.8	-1.5	0.7	-0.8	-1.0	-1.1	-1.7	-0.5
Worry (Nagel 2018)	0.3	0.6	1.4	0.8	0.2	-0.8	0.7	0.6	0.7	0.7	1.2
Alzheimer’s Disease (in mother)	0.4	0.4	1.0	-0.8	-0.6	0.7	-0.7	-0.4	-1.0	-0.3	-0.3
Alzheimer’s Disease (in father)	0.6	0.7	1.4	-1.1	-0.3	1.0	-0.9	-0.8	-1.2	0.5	-0.1
Alzheimer’s Disease (including proxy)	0.7	1.0	1.9	-1.4	-0.7	1.1	-1.2	-0.7	-1.4	-0.3	-0.5
Crohns Disease (2017)	0.1	0.1	0.8	-0.2	0.9	0.0	-0.3	-0.0	-0.1	0.3	-0.4
Irritable Bowel Disease (IBD)	0.1	0.3	1.5	-0.4	0.2	0.2	-0.4	0.4	0.0	1.2	-0.2
Ulcerative Colitis (UC)	0.3	0.5	1.8	-0.7	-0.6	0.7	-0.7	0.3	-0.1	1.3	-0.4
Major Depression (MDD)	0.9	1.1	2.1	-1.2	0.5	1.1	-1.2	-1.1	-1.4	-0.5	-0.8
Reaction Time	0.3	0.5	1.9	0.1	1.0	-0.2	0.1	0.8	0.2	1.4	0.5
Verbal and Numeric Reasoning (VNR)	1.7	4.1	6.1	2.1	1.3	-2.3	2.4	2.2	1.6	1.3	2.5
Breast Cancer	0.6	1.3	9.2	0.0	0.2	-0.2	-0.1	1.0	0.5	3.0	0.2
Ovarian Cancer	0.4	0.5	1.0	0.9	-0.3	-0.8	0.8	0.7	1.0	0.4	0.6
Prostate Cancer	0.4	0.6	2.5	0.5	-0.5	-0.5	0.4	0.4	1.0	-1.6	-0.1
Age at First Birth	0.5	0.7	2.3	0.7	0.5	-0.7	0.8	0.8	0.5	1.5	0.8
Bipolar Disorder (2011)	0.5	0.5	2.1	0.3	0.7	-0.3	0.3	0.7	0.5	1.4	0.4
Body Mass Index (BMI) (2010)	0.3	0.4	1.0	-0.7	0.8	0.6	-0.7	-0.3	-0.5	0.3	-1.0
Coronary Artery Disease (CAD)	0.0	0.1	0.3	-0.2	-0.1	0.2	-0.2	-0.1	-0.1	-0.2	-0.5
Crohns Disease (2012)	0.7	1.1	1.8	-1.1	-0.6	1.0	-1.2	-1.2	-1.0	-1.0	-1.4
Mean Putamen Volume	1.4	1.5	2.7	-1.3	0.1	1.4	-1.2	-1.3	-1.6	-1.2	-1.1
Fasting Glucose	0.1	0.1	0.4	0.4	0.6	-0.4	0.3	-0.0	0.5	-0.0	0.0
HbA1C	6.6	7.3	9.9	-2.5	-1.5	2.6	-2.7	-3.1	-3.0	-3.1	-2.8
HDL Cholesterol	0.3	0.6	1.0	-0.8	-0.6	1.0	-0.9	-0.8	-0.8	0.2	-0.7
LDL Cholesterol	0.3	0.5	1.4	-0.4	-0.9	0.5	-0.2	-0.4	-1.1	-1.2	-0.6
Lupus	0.1	0.1	0.2	0.1	-0.2	-0.2	0.1	0.4	0.4	0.5	0.2
Neuroticism (2016)	1.2	1.7	2.8	-1.5	-1.3	1.4	-1.7	-0.9	-1.4	-0.3	-1.3
Primary Biliary Cirrhosis	0.1	0.1	0.6	-0.0	0.5	0.1	-0.0	-0.2	-0.2	-0.8	-0.1
Rheumatoid Arthritis	0.4	0.6	2.6	0.1	-0.8	0.0	-0.1	-0.6	0.0	-1.6	-0.9
Schizophrenia (2014)	0.2	0.5	1.2	-0.7	-0.6	0.7	-0.8	-0.6	-1.1	-0.2	-0.0
Triglycerides	0.1	0.2	0.5	0.3	0.4	-0.2	0.3	0.5	0.3	0.1	0.7
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.8	0.2	0.1	-0.0	0.2	0.8	0.1	0.6	0.9
Ulcerative Colitis	0.3	0.4	1.9	0.1	0.7	-0.3	0.1	0.5	0.6	1.4	0.1
Blood Eosinophil Count	3.2	24.8	36.7	-5.0	-4.4	4.9	-4.9	-4.9	-4.4	-6.1	-5.2
Blood Platelet Count	0.0	0.5	2.2	0.1	0.2	0.2	-0.1	-0.2	0.5	-1.1	-1.5
Blood Red Count	2.2	21.4	30.5	-4.7	-5.5	4.4	-5.0	-5.0	-3.8	-4.5	-3.9
Blood White Count	0.1	1.0	5.7	-0.4	-1.1	0.2	-0.2	-0.6	-0.0	-2.4	-0.9
Heel T-Score	0.9	7.4	17.9	-2.1	-2.7	2.2	-2.2	-2.9	-2.2	-4.2	-2.5
BMI	0.8	4.7	8.2	-2.0	-1.2	2.2	-2.0	-2.1	-2.0	-2.9	-2.7
Height	0.3	5.4	7.3	-2.5	-2.7	2.5	-2.6	-2.3	-2.7	-1.2	-1.6
Waist Hip Ratio (WHR)	0.1	0.3	0.9	0.4	0.9	-0.6	0.5	0.3	0.3	0.2	0.5
Systolic Blood Pressure	0.7	3.7	5.6	2.4	1.9	-2.1	2.3	1.8	2.0	0.5	1.8
Smoking Status	0.1	0.3	1.4	0.4	1.2	-0.4	0.4	0.1	0.2	-0.2	-0.6
Allergy or Eczema	0.3	0.8	1.3	1.1	-0.2	-1.0	1.1	1.0	0.7	0.6	1.1
Cardiovascular Disease	0.5	1.6	5.7	-0.7	-2.4	1.1	-1.0	-0.9	-0.7	-1.6	-0.7
Hypothyroidism (self reported)	0.4	1.0	5.8	-0.2	-0.4	0.2	-0.4	-1.1	-0.2	-2.4	-0.8
Respiratory disease	1.1	2.4	3.6	-1.6	-1.4	1.6	-1.6	-1.8	-1.6	-0.3	-1.9
Type 2 Diabetes (T2D) (2018)	0.5	0.9	4.2	-0.5	-0.3	0.6	-0.5	-1.1	-0.8	-2.0	-0.5
Lung FEV1/FVC ratio	1.5	7.7	11.0	3.0	2.5	-2.5	2.7	2.7	3.3	3.3	1.9
Lung FVC	0.3	1.5	2.7	1.4	0.4	-1.3	1.3	1.3	1.6	0.4	1.4
Neuroticism	0.1	0.3	2.2	-0.3	-1.5	0.2	-0.4	-0.1	-0.1	-0.3	-0.1
Chronotype (morning person)	2.1	5.0	6.4	-2.5	-1.7	2.5	-2.5	-1.9	-2.5	-1.6	-2.3
Hair Pigment	0.1	4.1	5.7	2.3	2.0	-2.1	2.4	1.9	2.3	1.5	1.5
Tanning	0.2	2.6	3.9	-1.8	-1.4	1.9	-2.0	-1.4	-1.6	-0.6	-1.7
Hand grip strength (left)	2.1	5.6	7.5	-2.5	-2.7	2.5	-2.4	-2.4	-2.4	-1.8	-2.0
Number of treatments/medications taken	1.2	2.2	3.5	-1.6	-1.2	1.9	-1.7	-1.5	-1.7	-1.1	-1.0
Average weekly spirits intake	3.6	4.4	8.2	-2.0	-1.1	2.2	-1.9	-2.3	-2.2	-2.9	-1.6
Sensitivity / hurt feelings	0.2	0.4	1.6	-0.5	-0.8	0.5	-0.5	-0.3	-0.5	-1.3	-0.2
Frequency of depressed mood in last 2 weeks	0.0	0.1	0.2	0.0	-0.4	0.2	-0.1	-0.2	-0.3	-0.3	0.2
Hearing difficulty/problems: Yes	1.2	1.8	3.0	-1.6	-1.1	1.5	-1.7	-1.4	-1.4	-0.3	-1.4
Relative age of first facial hair	0.0	0.0	0.2	-0.1	0.3	-0.1	-0.0	-0.0	0.0	0.2	0.4
Other serious medical condition/disability diagnosed by doctor	1.7	2.2	3.4	-1.5	-1.6	1.8	-1.6	-1.3	-1.5	-1.4	-0.9
Ever used hormone-replacement therapy (HRT)	0.4	0.5	0.8	-0.9	-0.8	0.9	-0.8	-0.4	-0.7	-0.0	-0.5
Ever had hysterectomy (womb removed)	3.5	3.9	5.2	-2.2	-1.4	2.1	-2.3	-2.2	-2.2	-1.5	-1.6
Systolic blood pressure, automated reading	0.2	0.7	1.2	1.0	1.0	-0.9	1.1	0.5	0.6	-0.9	0.5
Eye problems/disorders: Diabetes related eye disease	0.2	0.3	0.6	0.8	-0.0	-0.7	0.6	0.1	0.6	-0.5	-0.0
Angina	0.9	1.1	1.9	-0.9	-0.8	1.1	-1.1	-1.4	-1.1	-1.1	-1.1
Medication for hormone replacement therapy	0.5	0.6	1.6	-0.5	-1.3	0.6	-0.7	-0.5	-0.1	-0.9	-0.8
Vitamin and mineral supplements	1.2	1.6	3.2	1.1	0.7	-1.5	1.3	1.8	1.4	1.2	0.9
Supplements: Zinc	0.2	0.2	0.9	0.1	1.0	-0.1	0.0	-0.3	0.0	-0.6	-0.3
Medication: Co-codamol	1.5	1.7	2.9	-1.3	-0.2	1.4	-1.5	-1.7	-1.1	-1.4	-1.3
Medication: Metformin	1.4	2.0	4.7	-1.1	-1.5	1.2	-1.2	-1.4	-1.3	-2.2	-0.9
Diabetes (father)	1.1	1.3	2.1	1.4	0.8	-1.3	1.4	1.3	1.5	-0.0	1.0
Diabetes (mother)	0.6	0.8	1.1	0.9	1.0	-0.8	1.0	0.9	1.0	1.0	0.5
Severe depression (siblings)	1.1	1.2	1.8	-1.2	-0.9	1.2	-1.3	-1.3	-1.3	-0.7	-0.6
Pack years adult smoking proportion	0.1	0.2	0.6	-0.2	0.4	0.1	-0.2	-0.8	-0.2	-0.7	-0.6
Impedance of leg (right)	0.0	0.1	0.8	-0.1	-0.0	-0.1	-0.0	0.3	0.3	0.9	-0.0
Leg fat-free mass (left)	0.3	1.6	2.3	-1.1	-1.3	1.2	-1.1	-1.2	-1.5	-1.4	-1.1
Trunk fat percentage	0.2	0.7	1.7	-0.5	-0.6	0.7	-0.5	-0.7	-0.4	-1.3	-1.3
Hand grip strength (right)	0.4	1.2	4.7	-1.0	-2.2	1.1	-1.0	-0.8	-0.9	-0.2	-0.7
Townsend deprivation index at recruitment	0.9	1.2	2.2	1.3	1.5	-1.1	1.4	0.8	0.7	-0.1	1.2
Current tobacco smoking	0.1	0.1	0.2	-0.3	0.5	0.2	-0.4	-0.3	-0.4	-0.3	-0.5
Average weekly fortified wine intake	7.4	8.7	10.8	-3.0	-3.0	3.2	-3.3	-3.1	-2.6	-2.1	-3.0
Maternal smoking around birth	1.2	1.7	2.9	1.6	0.7	-1.4	1.7	1.2	1.6	0.1	1.3
Fed-up feelings	1.2	2.1	3.1	1.4	1.3	-1.4	1.3	1.6	1.5	1.8	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	2.7	-0.9	-1.6	1.3	-1.2	-1.1	-1.1	-0.4	-0.7
Relative age voice broke	0.2	0.4	1.2	0.7	0.2	-0.7	0.6	0.2	1.1	0.3	0.6
Taking other prescription medications	1.1	1.6	2.6	-1.4	-1.1	1.6	-1.5	-1.3	-1.5	-0.6	-0.9
Age when periods started (menarche)	1.1	2.6	3.5	1.7	0.2	-1.9	1.7	1.8	1.8	1.8	1.3
Bilateral oophorectomy (both ovaries removed)	3.0	3.5	7.0	-1.5	-1.8	1.8	-1.7	-2.1	-2.0	-2.7	-1.0
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	2.3	-0.2	-0.4	0.2	-0.4	-0.6	0.4	-1.5	-1.0
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.5	-0.2	-0.1	0.7	-0.6	-0.4	0.2	0.5	-0.4
Qualifications: CSEs or equivalent	0.6	0.8	1.8	1.1	0.7	-1.0	1.0	0.8	1.3	-0.1	0.3
Serious illness, injury or assault to yourself	6.0	7.3	9.8	-2.9	-2.7	2.9	-2.8	-2.6	-3.1	-2.1	-2.3
High blood pressure	0.1	0.2	0.5	-0.3	-0.7	0.7	-0.5	-0.4	-0.3	-0.3	-0.2
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.1	0.8	0.0	-0.7	0.8	0.9	0.6	1.0	1.0
Multivitamins +/- minerals	1.1	1.4	3.3	-0.7	-1.1	1.1	-0.8	-1.5	-1.1	-1.8	-0.9
Stomach or abdominal pain in last month	1.3	1.6	2.8	-1.6	-0.8	1.5	-1.7	-1.0	-1.1	-0.3	-1.5
Supplements: Glucosamine	1.5	2.0	2.9	-1.4	-0.8	1.5	-1.5	-1.7	-1.4	-1.4	-1.6
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	2.3	-0.7	-1.5	0.7	-0.7	-0.5	-0.4	-0.7	-1.0
Medication: Atenolol	0.1	0.1	0.3	0.3	0.1	-0.3	0.0	-0.1	-0.0	0.1	0.6
Medication: Levothyroxine sodium	0.3	0.5	2.3	-0.1	-0.8	0.1	-0.4	-0.8	-0.0	-1.5	-0.4
Sitting height	0.3	2.0	4.9	-1.4	-2.2	1.3	-1.5	-1.0	-1.5	-0.3	-1.2
Chronic bronchitis/emphysema (father)	0.3	0.3	1.0	0.1	-1.0	-0.0	-0.0	0.4	0.5	1.0	0.2
High blood pressure (mother)	0.2	0.2	0.6	0.7	0.1	-0.4	0.6	0.2	0.4	0.1	0.8
Body mass index (BMI)	0.2	0.7	2.9	-0.4	-0.3	0.6	-0.4	-0.8	-0.4	-1.7	-1.2
Impedance of leg (left)	0.0	0.2	0.7	0.1	0.3	-0.3	0.2	0.4	0.5	0.8	-0.1
Leg predicted mass (left)	0.4	1.9	2.7	-1.2	-1.5	1.4	-1.2	-1.4	-1.6	-1.5	-1.2
Trunk fat mass	0.3	1.2	2.4	-0.8	-0.9	1.0	-0.8	-1.0	-0.8	-1.6	-1.5
Waist circumference	0.2	0.6	2.0	-0.5	0.2	0.6	-0.5	-0.8	-0.7	-1.4	-1.0
Number of incorrect matches in round	2.2	3.6	5.3	-1.8	-1.5	2.0	-2.0	-2.3	-1.5	-2.0	-2.0
Past tobacco smoking	0.1	0.2	0.4	-0.6	-0.1	0.5	-0.6	-0.1	-0.4	0.5	0.4
Alcohol usually taken with meals	0.1	0.1	0.3	-0.0	-0.6	-0.1	0.0	-0.4	-0.1	-0.5	0.3
Nervous feelings	0.8	1.6	3.2	1.4	0.8	-1.2	1.2	1.0	1.2	1.1	1.8
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	1.2	-0.0	-1.1	0.2	-0.1	0.1	-0.1	0.3	0.5
Hearing difficulty/problems with background noise	0.3	0.5	2.5	-0.6	-1.6	0.6	-0.7	-0.8	-0.3	-0.1	-0.2
Hair/balding pattern: Pattern 2	0.2	0.2	1.2	0.4	-1.1	-0.1	0.3	0.1	0.5	0.1	0.0
Had menopause	0.9	1.1	5.2	0.3	0.7	-0.3	0.2	1.3	0.4	2.3	1.2
Had other major operations	1.0	1.2	2.1	-1.1	-1.5	0.9	-1.2	-1.0	-1.0	-0.7	-1.4
Forced vital capacity (FVC)	0.2	0.6	0.8	-0.8	-0.9	0.7	-0.8	-0.8	-0.8	-0.3	-0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	1.6	0.5	0.2	-0.4	0.3	-0.1	0.8	-1.3	-0.3
Ever unenthusiastic/disinterested for a whole week	1.3	1.6	2.7	-1.4	-0.7	1.3	-1.4	-1.4	-1.3	-0.4	-1.6
Qualifications: None of the above	0.1	0.1	0.3	0.5	0.5	-0.4	0.5	0.1	0.3	-0.3	0.3
Financial difficulties in last 2 years	1.4	1.9	3.0	1.7	1.3	-1.7	1.7	1.3	1.4	0.2	1.0
Mouth/teeth dental problems	0.9	1.4	2.4	-1.5	-1.3	1.3	-1.5	-1.2	-1.2	0.1	-0.9
Heart attack	1.1	1.3	1.6	-1.2	-1.0	1.3	-1.2	-1.3	-1.3	-1.0	-1.1
Allergy	0.1	0.3	1.1	0.3	1.1	-0.5	0.4	0.4	0.4	0.1	0.2
Pain all over the body in last month	1.5	1.6	3.7	-1.1	-1.9	1.4	-1.5	-1.1	-0.9	-0.4	-1.2
Diabetes (self-reported)	0.6	0.9	4.9	-0.5	-0.3	0.5	-0.4	-1.0	-0.9	-2.2	-0.1
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	2.3	-0.5	-1.5	0.4	-0.4	-0.2	-0.7	-1.0	-0.3
Medication: Ramipril	0.1	0.1	0.2	0.4	-0.3	-0.4	0.4	0.2	0.2	-0.3	0.4
Medication: Simvastatin	0.5	0.7	1.7	-0.4	-1.0	0.5	-0.5	-0.9	-0.7	-1.3	-0.9
Fluid intelligence score	1.2	2.4	3.9	1.6	1.1	-1.8	1.8	1.8	1.1	1.1	2.0
Illnesses of siblings	0.3	0.4	1.1	-0.1	-1.1	0.0	0.2	0.8	0.3	1.0	-0.1
Neuroticism score	0.1	0.2	1.3	0.2	-1.2	-0.1	-0.0	0.2	0.4	-0.1	0.2
Weight	0.3	1.4	2.6	-0.9	-1.1	1.1	-0.9	-1.2	-1.1	-1.6	-1.4
Impedance of arm (right)	0.4	1.8	2.5	1.3	0.9	-1.2	1.2	1.4	1.6	1.4	1.4
Arm fat percentage (right)	0.1	0.4	2.1	-0.2	-0.2	0.5	-0.2	-0.5	-0.1	-1.4	-0.9
Trunk fat-free mass	0.4	2.2	3.5	-1.3	-1.7	1.4	-1.3	-1.5	-1.9	-1.5	-1.2
Hip circumference	0.6	2.8	6.2	-1.4	-1.0	1.6	-1.4	-1.7	-1.6	-2.5	-1.7
Time employed in main current job	0.0	0.1	0.1	0.3	0.1	-0.3	0.4	0.1	0.1	-0.2	0.2
Alcohol intake versus 10 years previously	0.1	0.1	0.2	0.5	0.4	-0.3	0.4	-0.1	0.2	0.0	0.1
Father’s age at death	1.9	2.6	4.7	-1.9	-2.2	1.7	-1.8	-1.4	-1.7	-0.9	-0.9
Worrier / anxious feelings	0.9	1.7	2.2	-1.3	-1.3	1.5	-1.5	-1.3	-1.4	-1.0	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.5	0.7	-0.2	-0.6	0.5	0.1	0.5	0.3	0.5
Falls in the last year	1.2	1.6	2.5	-1.2	-1.6	1.3	-1.3	-1.3	-1.4	-0.9	-1.1
Hair/balding pattern: Pattern 3	0.1	0.2	0.7	-0.3	-0.8	0.3	-0.4	-0.3	-0.2	-0.4	-0.3
Number of live births	1.8	2.5	3.1	-1.7	-1.1	1.6	-1.8	-1.8	-1.6	-1.3	-1.7
Forced expiratory volume in 1-second (FEV1)	0.0	0.1	0.3	0.4	-0.1	-0.3	0.2	0.1	0.6	0.5	-0.1
Pulse rate	0.1	0.1	0.5	-0.4	0.1	0.2	-0.3	-0.0	-0.1	-0.7	-0.4
Happiness	0.2	0.2	0.9	0.3	-1.0	-0.2	0.2	0.5	0.6	-0.1	0.3
Noisy workplace	0.1	0.1	0.4	0.1	0.6	0.0	-0.2	-0.2	0.4	0.4	-0.6
Qualifications: A levels/AS levels or equivalent	1.9	4.3	5.4	-2.3	-1.9	2.2	-2.3	-2.0	-2.1	-1.4	-2.3
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	2.3	-1.4	-1.4	1.5	-1.4	-0.9	-1.5	-0.5	-0.9
Mouth/teeth dental problems: Dentures	0.2	0.3	1.0	0.6	-0.5	-0.2	0.4	-0.0	0.4	-1.0	-0.2
Asthma	0.6	1.2	2.1	-0.9	-1.1	1.3	-1.1	-1.2	-0.9	-0.5	-1.4
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	1.3	0.4	1.1	-0.5	0.6	0.9	0.4	1.1	1.1
Medication: Cholesterol lowering	0.9	1.4	2.7	-1.0	-1.1	1.0	-1.0	-1.3	-1.0	-1.6	-1.2
Depression (self-reported)	0.2	0.3	0.8	-0.3	-0.9	0.2	-0.4	-0.2	-0.2	-0.9	-0.4
Medication: Lansoprazole	0.8	0.9	1.4	1.0	0.2	-0.9	1.0	1.2	0.8	1.0	1.1
Prospective memory result	0.7	0.9	1.2	1.0	1.0	-1.1	1.0	0.9	0.8	1.0	0.7
Lung cancer (father)	0.1	0.1	0.6	0.1	-0.0	-0.1	0.3	0.8	0.3	-0.3	-0.3
Illnesses of mother	0.8	1.0	1.7	-1.3	-0.9	1.2	-1.2	-0.3	-1.2	-0.0	-1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.1	0.3	0.3	-0.4	-0.2	0.2	0.2	0.4	0.5	-0.2
Pulse wave Arterial Stiffness index	0.4	0.5	2.2	-0.1	-0.1	0.2	-0.3	-1.0	0.0	-1.5	-0.9
Impedance of arm (left)	0.1	0.4	1.1	0.5	0.3	-0.4	0.4	0.6	0.8	1.1	0.7
Arm fat mass (right)	0.3	1.1	3.2	-0.6	-0.6	0.9	-0.7	-1.1	-0.7	-1.8	-1.4
Trunk predicted mass	0.4	2.3	3.5	-1.3	-1.7	1.4	-1.4	-1.6	-1.9	-1.6	-1.2
Standing height	0.2	1.8	4.2	-1.4	-2.0	1.3	-1.4	-1.1	-1.7	-0.3	-0.8
Length of working week for main job	0.4	0.4	0.9	0.7	0.9	-0.6	0.5	0.3	0.9	-0.5	0.0
Exposure to tobacco smoke at home	0.2	0.2	0.7	-0.0	0.8	0.2	0.1	-0.3	-0.6	-0.7	-0.2
Breastfed as a baby	0.6	0.7	1.0	-0.8	-0.1	1.0	-1.0	-1.0	-0.9	-1.0	-0.5
Tense / ‘highly strung’	1.0	1.7	5.0	-1.0	-2.2	1.0	-1.1	-1.3	-0.7	-1.5	-0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	3.1	0.5	0.4	-0.7	0.6	0.9	0.6	1.8	0.5
Hair/balding pattern: Pattern 4	0.7	1.6	3.2	1.4	0.8	-1.3	1.4	1.1	1.8	0.4	1.3
Birth weight of first child	0.2	0.3	1.9	0.1	-0.2	-0.1	0.1	0.2	0.0	1.4	0.8
Peak expiratory flow (PEF)	0.4	0.9	1.8	1.1	1.4	-1.0	1.0	0.4	1.2	0.4	0.5
Pulse wave reflection index	0.4	0.5	0.8	-0.7	-0.5	0.7	-0.7	-0.7	-0.6	-0.7	-0.9
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.3	0.2	0.6	-0.5	0.2	0.3	0.5	-0.1	-0.1
Loud music exposure frequency	1.2	1.3	2.0	-1.3	-0.5	1.2	-1.4	-1.1	-1.1	-0.9	-1.3
Qualifications: O levels/GCSEs or equivalent	1.8	2.9	4.2	-1.9	-1.8	2.0	-2.0	-1.5	-1.5	-0.9	-1.6
Mouth/teeth dental problems: Bleeding gums	2.9	3.8	4.9	2.1	2.2	-2.1	2.2	2.2	1.9	1.1	1.6
Blood clot in the leg (DVT)	1.5	2.0	3.0	-1.2	-1.7	1.4	-1.4	-1.5	-1.1	-1.7	-1.2
Medication: Paracetamol	0.9	1.5	2.3	-1.4	-0.9	1.5	-1.5	-1.2	-1.1	-0.9	-1.1
Headache pain in last month	0.2	0.3	0.8	-0.5	0.2	0.8	-0.6	-0.5	-0.4	0.9	-0.2
Medication for cholesterol, blood pressure or diabetes	1.2	2.1	2.8	1.4	1.2	-1.5	1.4	1.7	1.3	1.4	1.5
Glaucoma (self-reported)	1.1	1.3	2.1	-1.4	-0.8	1.3	-1.4	-1.0	-1.5	-0.2	-0.9
Gout (self-reported)	0.2	0.2	1.1	0.1	1.1	-0.3	0.3	0.3	0.4	-0.2	0.4
Hypothyroidism/myxoedema (self-reported)	0.6	1.3	5.3	-0.5	-1.1	0.5	-0.6	-1.3	-0.5	-2.3	-0.8
Medication: Amlodipine	1.0	1.4	2.2	1.5	0.1	-1.4	1.4	1.3	1.2	1.0	1.0
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.5	0.6	0.5	-0.6	0.6	0.3	0.4	0.7	0.4
Birth weight	0.9	1.9	3.9	1.3	1.3	-1.4	1.3	1.6	1.1	2.0	0.8
Chronic bronchitis/emphysema (mother)	1.6	1.9	7.1	-1.1	-2.7	1.1	-1.2	-1.1	-0.9	-1.0	-1.1
High blood pressure (siblings)	0.4	0.6	2.0	-0.4	0.5	0.6	-0.4	-1.0	-1.0	-1.4	-0.0
Forced vital capacity (FVC), Best measure	0.3	0.9	1.8	-0.9	-1.4	0.9	-0.9	-0.8	-1.0	-0.5	-1.0
Body fat percentage	0.1	0.5	1.5	-0.4	-0.3	0.6	-0.4	-0.6	-0.3	-1.1	-1.2
Leg fat percentage (right)	0.3	1.0	2.6	-0.7	-0.5	1.0	-0.8	-1.0	-0.6	-1.3	-1.6
Arm fat-free mass (right)	0.6	3.1	4.6	-1.6	-1.7	1.6	-1.6	-1.8	-2.1	-1.7	-1.7
Exposure to tobacco smoke outside home	0.3	0.4	1.1	0.9	0.2	-0.6	0.7	0.5	1.1	0.0	0.2
Comparative body size at age 10	0.8	2.1	3.0	-1.5	-0.9	1.7	-1.4	-1.5	-1.7	-1.0	-1.6
Number of full brothers	0.9	1.1	2.1	-0.9	-0.9	1.1	-1.1	-1.4	-0.9	-1.0	-1.0
Worry too long after embarrassment	0.6	1.0	2.9	-0.9	-1.7	1.0	-0.9	-0.5	-0.8	-0.8	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.6	-0.4	-0.5	0.7	-0.6	-0.4	-0.5	0.4	-0.8
Wheeze or whistling in the chest in last year	1.7	3.1	6.0	-1.8	-0.8	1.9	-1.8	-1.7	-1.6	-1.4	-2.5
Number of children fathered	0.4	0.4	1.0	-0.7	-1.0	0.6	-0.9	-0.7	-0.3	0.1	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.5	-0.6	-0.5	0.4	-0.7	-0.5	-0.2	0.7	-0.3
Age at first live birth	0.8	1.4	2.1	1.4	0.8	-1.0	1.2	0.9	1.5	1.3	1.1
Pulse wave peak to peak time	0.3	0.4	2.0	-0.1	-0.2	0.0	0.0	0.8	-0.2	1.4	0.7
Health satisfaction	0.5	0.7	1.2	1.1	0.5	-1.1	1.0	0.4	1.1	-0.1	0.6
Shortness of breath walking on level ground	0.8	1.0	1.6	-1.0	-1.1	1.0	-1.1	-0.8	-0.8	-1.3	-0.7
Qualifications: College or University degree	0.2	0.6	1.5	-0.9	-1.2	0.8	-0.8	-0.3	-0.7	0.2	-0.6
Eye problems/disorders: None of the above	0.3	0.4	1.0	-0.6	-0.4	0.4	-0.6	-0.6	-0.5	-1.0	-0.5
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.6	0.4	0.6	-0.4	0.5	0.8	0.2	-0.2	0.4
Emphysema/chronic bronchitis	1.3	1.5	3.3	-1.4	-0.7	1.3	-1.4	-1.2	-1.8	-0.2	-0.8
Medication for pain relief, constipation, heartburn	0.7	1.2	1.8	1.2	0.7	-1.3	1.2	1.1	1.1	1.2	0.8
Neck or shoulder pain in last month	1.7	2.4	6.0	1.2	1.4	-1.3	1.2	1.9	1.2	2.4	1.2
Medication: Blood pressure	0.5	0.9	1.3	-1.0	-0.7	1.1	-1.0	-1.1	-0.9	-0.8	-0.9
Angina (self-reported)	1.0	1.3	1.9	-1.0	-0.9	1.2	-1.2	-1.4	-1.1	-1.1	-1.2
Migraine (self-reported)	0.2	0.3	0.6	-0.7	0.2	0.4	-0.5	-0.6	-0.8	-0.3	-0.4
Medication: Ibuprofen	0.9	1.0	2.9	0.5	1.3	-0.6	0.7	1.0	0.6	1.7	1.2
Medication: Allopurinol	0.2	0.3	2.0	0.1	1.4	-0.3	0.3	0.2	0.3	0.0	0.4
Medication: Omeprazole	1.4	1.7	3.6	-1.2	-1.9	1.4	-1.3	-1.4	-1.1	-0.8	-1.1
Medication: Seretide 50 evohaler	0.2	0.2	0.7	-0.2	0.5	0.1	-0.3	-0.5	0.1	-0.7	-0.8
Mean time to correctly identify matches	0.2	0.4	1.1	-0.7	0.3	0.6	-0.6	0.2	-0.7	1.1	-0.0
Heart disease (mother)	0.1	0.1	0.3	0.3	0.2	-0.1	0.1	-0.6	0.4	-0.1	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	2.0	1.3	0.4	-1.2	1.4	1.3	1.1	-0.3	0.8
Whole body fat mass	0.3	1.4	3.0	-0.8	-0.8	1.1	-0.9	-1.1	-0.9	-1.7	-1.6
Leg fat mass (right)	0.5	1.8	3.4	-1.1	-0.8	1.4	-1.2	-1.3	-1.1	-1.7	-1.8
Arm predicted mass (right)	0.4	2.0	3.0	-1.3	-1.4	1.2	-1.2	-1.4	-1.7	-1.5	-1.4
Pulse rate, automated reading	0.1	0.5	0.8	-0.8	-0.6	0.7	-0.7	-0.3	-0.2	-0.8	-0.9
Alcohol intake frequency.	0.4	0.9	1.4	1.2	0.5	-1.0	1.0	0.9	0.9	0.8	1.1
Comparative height size at age 10	0.0	0.1	0.2	0.1	-0.1	-0.3	0.1	0.0	-0.3	0.4	0.5
Number of full sisters	5.4	6.5	9.7	3.1	2.5	-2.8	2.9	2.5	2.6	1.1	2.3
Suffer from ‘nerves’	0.9	1.4	2.2	1.2	1.1	-1.3	1.2	1.1	1.1	0.7	1.5
Overall health rating	1.8	3.8	5.9	2.4	1.5	-2.4	2.3	1.8	2.2	0.7	1.7
Chest pain or discomfort	1.3	1.8	3.9	-1.0	-0.6	1.2	-1.1	-1.8	-1.5	-2.0	-1.1
Had major operations	0.1	0.1	0.6	0.2	0.2	-0.1	0.4	0.4	0.1	-0.0	0.8
Age at last live birth	1.9	2.7	4.8	2.1	1.2	-1.7	1.8	1.4	2.2	1.3	1.1
Family relationship satisfaction	1.2	1.5	2.3	-1.5	-1.4	1.2	-1.4	-1.1	-1.2	-0.3	-1.3
Leg pain on walking	0.4	0.5	2.6	0.7	0.2	-0.6	0.8	0.1	0.2	-1.6	0.4
Qualifications: NVQ or HND or HNC or equivalent	2.1	2.6	5.1	1.5	2.3	-1.8	1.6	1.4	1.5	1.0	1.5
Commuting to job workplace: Car/motor vehicle	1.1	1.3	1.8	1.1	1.1	-1.1	1.1	1.3	1.3	1.1	0.9
Illness, injury, bereavement, stress in last 2 years	1.6	1.9	3.4	1.6	1.8	-1.4	1.5	1.0	1.6	0.4	1.2
Medication: Aspirin	1.6	2.1	3.2	-1.3	-1.2	1.4	-1.5	-1.8	-1.4	-1.7	-1.1
Supplements: Vitamin C	3.0	3.5	4.7	-2.0	-1.3	2.1	-2.1	-2.2	-2.0	-0.9	-1.9
Knee pain experienced in last month	1.6	2.5	3.3	-1.7	-0.6	1.8	-1.6	-1.7	-1.7	-1.4	-1.6
Hypertension (Self-reported)	0.0	0.1	0.4	-0.1	-0.7	0.5	-0.3	-0.2	-0.2	-0.5	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	0.8	-0.8	-0.9	0.8	-0.8	-0.6	-0.5	0.7	-0.7
Illnesses of father: Heart disease	0.3	0.4	1.9	0.0	-1.0	-0.0	-0.1	-0.6	0.3	-1.4	-0.5
Illnesses of siblings: Diabetes	0.5	0.7	2.1	0.9	1.4	-0.8	0.6	-0.1	0.9	-0.5	0.6
Smoking status: Previous	0.1	0.1	0.2	0.4	0.1	-0.4	0.4	0.2	0.3	-0.2	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.3	0.4	-0.6	-0.7	0.5	-0.5	-0.5	-0.6	-0.5	-0.6
Whole body fat-free mass	0.4	2.1	3.2	-1.2	-1.6	1.3	-1.3	-1.5	-1.8	-1.5	-1.2
Leg fat-free mass (right)	0.3	1.5	2.3	-1.1	-1.2	1.1	-1.0	-1.2	-1.5	-1.5	-1.1
Arm fat percentage (left)	0.2	0.8	2.6	-0.5	-0.4	0.8	-0.5	-0.8	-0.4	-1.6	-1.2
Average weekly red wine intake	0.2	0.3	1.6	-0.3	-1.3	0.3	-0.3	-0.2	-0.4	-0.2	-0.3
Handedness (chirality/laterality): Left-handed	0.2	0.3	0.5	0.6	-0.1	-0.5	0.5	0.7	0.7	0.0	0.5
Mood swings	0.1	0.2	0.8	-0.2	-0.7	0.2	-0.3	-0.3	-0.2	-0.9	-0.5
Loneliness, isolation	0.3	0.4	1.8	-0.5	-1.3	0.5	-0.7	-0.1	-0.2	0.3	-0.4
Long-standing illness, disability or infirmity	1.8	2.8	3.7	-1.7	-1.9	1.8	-1.8	-1.7	-1.9	-1.1	-1.3
Ever had bowel cancer screening	4.6	5.4	7.5	-2.4	-2.6	2.7	-2.6	-2.2	-2.2	-1.3	-2.2
Diabetes diagnosed by doctor	0.4	0.7	4.7	-0.2	-0.2	0.3	-0.1	-0.9	-0.5	-2.2	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	2.4	0.3	-0.2	-0.3	0.2	0.3	0.5	1.6	0.5
Friendships satisfaction	1.7	2.1	3.5	-1.7	-1.9	1.3	-1.4	-1.2	-1.6	-1.3	-1.3
Qualifications: nursing, teaching	2.6	4.1	9.8	-2.2	-3.1	2.2	-2.2	-1.3	-1.9	-0.6	-1.7
Commuting to job workplace: Walk	1.2	1.3	2.2	-1.3	-0.8	1.2	-1.3	-1.0	-1.2	-0.1	-1.5
Eye problems/disorders: Cataract	0.2	0.2	0.7	0.4	0.3	-0.5	0.5	0.5	0.1	0.3	0.8
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.1	-1.1	-0.3	1.0	-0.8	-0.6	-0.8	0.3	-0.9
Medication for cholesterol	0.2	0.3	0.8	-0.7	0.2	0.4	-0.5	-0.4	-0.6	0.9	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.5	-0.3	-0.7	0.3	-0.4	-0.5	-0.3	-0.6	-0.1
Back pain experienced in last month	0.2	0.3	1.1	-0.6	-0.3	0.4	-0.4	-0.2	-1.1	0.4	-0.2
Mineral and other dietary supplements	1.7	2.2	3.8	1.5	0.3	-1.5	1.6	1.9	1.8	1.3	1.5
Breast cancer (self-reported)	1.0	1.2	2.0	1.1	1.2	-1.2	1.3	0.9	0.7	0.0	1.4
Asthma (self-reported)	0.9	1.9	3.1	-1.2	-1.3	1.6	-1.4	-1.5	-1.2	-0.7	-1.7
Osteoporosis (self-reported)	0.2	0.2	1.0	0.3	0.4	-0.3	0.3	0.4	0.1	1.0	0.4
Osteoarthritis (self-reported)	0.0	0.0	0.1	0.3	0.1	0.1	0.2	-0.3	0.2	0.1	0.2
Medication: Aspirin	0.9	1.1	1.9	-1.0	-0.8	1.1	-1.1	-1.4	-1.1	-1.3	-0.7
Medication: Gliclazide	1.3	1.5	2.5	-1.3	-0.1	1.5	-1.4	-1.6	-1.3	-1.0	-0.9
Illnesses of father: None of the above (group 1)	0.2	0.3	0.9	0.1	1.0	-0.1	0.2	0.7	-0.1	0.7	0.2
Smoking status: Current	0.1	0.2	0.3	-0.4	0.4	0.3	-0.5	-0.6	-0.5	-0.4	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	1.3	1.1	0.7	-1.1	1.1	0.9	1.1	0.7	1.2
Whole body water mass	0.4	2.0	3.2	-1.2	-1.6	1.3	-1.2	-1.4	-1.8	-1.5	-1.2
Leg predicted mass (right)	0.3	1.4	2.1	-1.0	-1.1	1.1	-1.0	-1.2	-1.4	-1.4	-1.1
Arm fat mass (left)	0.4	1.7	4.2	-0.9	-0.9	1.2	-0.9	-1.3	-1.0	-2.0	-1.6
Number of self-reported non-cancer illnesses	2.1	3.7	6.6	-1.8	-2.6	2.0	-1.8	-1.9	-2.0	-1.7	-1.3
Average weekly champagne plus white wine intake	0.1	0.2	0.5	-0.2	-0.2	0.3	-0.2	-0.6	0.1	-0.5	-0.7
Miserableness	1.4	2.4	3.9	1.7	1.3	-1.7	1.5	1.4	2.0	1.6	1.0
Guilty feelings	2.9	4.4	8.0	-2.2	-2.8	2.2	-2.3	-2.0	-1.9	-1.8	-1.4
Wears glasses or contact lenses	0.2	0.2	1.0	0.0	-0.3	0.0	0.1	-0.2	-0.5	-1.0	0.3
Ever taken oral contraceptive pill	1.4	1.6	3.1	-1.2	-1.8	1.2	-1.2	-1.1	-1.1	-1.4	-0.9
Hearing aid user	0.2	0.2	0.5	-0.5	-0.7	0.4	-0.5	-0.6	-0.4	-0.1	-0.5
Mother’s age at death	0.1	0.2	0.4	-0.5	-0.0	0.4	-0.4	-0.5	-0.7	-0.4	-0.1
Financial situation satisfaction	0.3	0.4	2.9	0.1	-0.4	-0.3	0.2	-0.3	-0.2	-1.7	-0.2
Tinnitus: Yes, now most or all of the time	0.2	0.3	0.9	-0.5	-0.5	0.4	-0.4	-0.6	-1.0	-0.3	-0.1
Commuting to job workplace: Public transport	0.3	0.4	1.2	-0.6	-0.5	0.5	-0.5	-0.5	-0.8	-1.1	-0.2
Eye problems/disorders: Glaucoma	0.9	1.1	1.8	-1.2	0.1	1.3	-1.3	-1.2	-1.2	-0.1	-1.0
Medication: Blood pressure	0.1	0.2	0.4	-0.5	-0.5	0.6	-0.5	-0.1	-0.4	-0.1	-0.2
Pain type(s) experienced in last month: Hip pain	0.0	0.0	0.1	-0.2	-0.1	0.3	-0.3	-0.3	-0.1	-0.0	-0.2
Supplements: Fish oil (including cod liver oil)	2.6	3.4	5.3	-1.8	-1.0	1.8	-1.9	-2.3	-2.2	-1.8	-1.6
High cholesterol (Self-reported)	0.3	0.6	3.1	-0.3	-1.8	0.6	-0.5	-0.6	-0.5	-0.6	-0.1
Medication: Bendroflumethiazide	0.1	0.2	0.6	-0.5	-0.8	0.6	-0.5	-0.1	-0.5	0.1	-0.3
Medication: Paracetamol	0.7	1.1	1.7	-1.2	-0.3	1.3	-1.3	-1.2	-1.1	-0.5	-1.0
Medication: Lisinopril	0.2	0.3	0.5	-0.7	-0.4	0.7	-0.6	-0.5	-0.6	-0.6	-0.2
Medication: Atorvastatin	0.4	0.5	2.2	-0.2	-1.2	0.3	-0.2	-0.2	-0.4	-1.5	0.0
Illnesses of father: High blood pressure	0.3	0.3	0.7	-0.5	-0.0	0.5	-0.6	-0.8	-0.5	-0.7	-0.6
Alcohol drinker status: Never	0.2	0.2	0.8	-0.3	-0.3	0.4	-0.5	-0.5	-0.4	-0.9	-0.1
Ever smoked	0.1	0.1	0.2	0.4	-0.1	-0.5	0.4	0.1	0.3	-0.5	-0.3
Basal metabolic rate	0.4	2.1	3.0	-1.2	-1.5	1.3	-1.2	-1.5	-1.7	-1.7	-1.3
Leg fat percentage (left)	0.3	1.0	3.0	-0.8	-0.4	1.0	-0.8	-1.0	-0.6	-1.3	-1.7
Arm fat-free mass (left)	0.3	1.5	2.1	-1.0	-1.2	1.1	-1.1	-1.2	-1.4	-1.3	-1.2
Number of operations (self-reported)	1.0	1.5	2.2	-1.3	-1.2	1.5	-1.4	-1.3	-1.2	-0.4	-1.0
Average weekly beer plus cider intake	0.2	0.3	0.6	0.6	0.3	-0.7	0.8	0.4	0.3	0.4	0.6
Irritability	1.1	1.8	3.3	1.4	0.9	-1.3	1.4	1.3	1.5	0.7	1.8
Risk taking	10.1	14.8	17.9	-4.2	-3.0	4.1	-4.2	-4.1	-3.9	-2.8	-4.2
Ever had prostate specific antigen (PSA) test	0.3	0.4	2.5	-0.4	-1.6	0.3	-0.2	0.3	-0.1	0.6	-0.0
Fractured/broken bones in last 5 years	1.0	1.2	2.1	-1.2	-0.4	1.2	-1.2	-1.5	-1.3	-0.2	-1.2
Age started oral contraceptive pill	0.3	0.4	0.7	-0.6	-0.4	0.8	-0.7	-0.9	-0.6	0.5	0.4
Diastolic blood pressure, automated reading	0.3	1.0	2.4	-0.6	-1.1	0.6	-0.6	-0.9	-0.5	-1.5	-1.6
Ever depressed for a whole week	0.8	1.0	1.8	-1.2	-0.9	1.0	-1.2	-0.7	-0.9	-0.1	-1.4
Unable to work because of sickness or disability	1.2	1.6	2.3	-1.2	-0.6	1.3	-1.3	-1.4	-1.3	-1.3	-1.5
Commuting to job workplace: Cycle	1.4	1.7	2.7	1.2	1.6	-1.2	1.2	1.0	1.1	1.6	1.2
Myopia	0.7	1.0	1.8	1.2	0.6	-1.2	1.2	0.9	0.8	-0.3	1.4
Vascular/heart problems diagnosed by doctor	0.2	0.6	1.1	0.7	1.0	-1.0	0.9	0.7	0.7	0.3	0.5
Cholesterol lowering medication	0.9	1.3	2.6	-0.8	-1.4	1.0	-0.9	-1.2	-1.3	-1.6	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	2.2	-1.1	-1.5	1.2	-1.0	-1.0	-1.0	-0.6	-0.9
Pain experienced in last month	0.6	1.1	1.6	1.2	0.8	-1.3	1.2	0.9	1.2	-0.4	1.0
Supplements: Calcium	2.7	2.9	6.5	1.4	2.1	-1.4	1.2	1.4	1.4	2.5	1.7
Basal cell carcinoma (self-reported)	3.2	3.7	5.1	-2.2	-0.7	2.2	-2.3	-2.2	-2.2	-1.2	-1.9
Heart attack/myocardial infarction (self-reported)	1.3	1.7	2.0	-1.4	-1.1	1.4	-1.3	-1.4	-1.4	-1.1	-1.2
Deep venous thrombosis (DVT) (self-reported)	1.3	1.7	3.0	-1.0	-1.7	1.2	-1.2	-1.4	-1.0	-1.6	-1.1
Heart disease (siblings)	0.7	0.9	1.4	-0.7	-1.1	0.8	-1.0	-1.2	-0.9	-1.0	-0.9
Alcohol drinker status: Previous	0.2	0.2	0.4	-0.4	-0.1	0.4	-0.5	-0.3	-0.5	0.6	-0.5
Pack years of smoking	0.1	0.2	0.5	-0.3	0.3	0.2	-0.3	-0.7	-0.3	-0.6	-0.6
Impedance of whole body	0.2	0.9	2.8	0.6	0.7	-0.8	0.7	1.0	1.1	1.7	0.8
Leg fat mass (left)	0.5	1.9	3.6	-1.1	-0.8	1.3	-1.1	-1.3	-1.1	-1.8	-1.9
Arm predicted mass (left)	0.4	2.1	3.0	-1.2	-1.4	1.3	-1.2	-1.4	-1.7	-1.5	-1.4