TWAS hub - USP30-AS1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Colon Transverse	0.187	0.0700	7.3e-03	0.052	NA	0.022	NA	0.039	0.00170	NA	3.1e-02	NA	0.0061
2	GTEx	Lung	0.155	0.0469	1.5e-05	0.024	NA	0.067	NA	0.034	0.00540	NA	7.5e-06	NA	0.0012
3	GTEx	Muscle Skeletal	0.121	0.0472	5.6e-03	0.037	NA	0.008	NA	0.011	0.00013	NA	5.3e-02	NA	0.0260

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Blood Platelet Count	19.2	222.1	458.0	9.1	11.2	21.4
Alzheimer’s Disease (in father)	5.2	5.6	9.9	-3.1	2.6	-0.4
Miserableness	5.1	8.8	23.4	1.1	-4.8	-1.3
HDL Cholesterol	4.7	7.8	23.3	0.2	-4.8	-0.4
Alzheimer’s Disease (in mother)	4.2	5.0	8.6	-0.0	-2.5	-2.9
Medication: Blood pressure	4.2	7.3	17.5	-0.3	4.2	2.1
Frequency of tiredness / lethargy in last 2 weeks	4.1	6.7	14.9	-0.3	-3.9	-2.3
Neuroticism (Nagel 2018)	3.9	9.1	25.2	0.5	-5.0	-1.3
Hearing difficulty/problems: Yes	3.1	4.7	9.3	1.5	-3.0	1.6
Medication: Amlodipine	3.1	4.4	7.1	0.8	2.7	2.3
Vascular/heart problems diagnosed by doctor	3.1	8.3	14.7	-0.5	-3.8	-3.2
Neuroticism	2.9	6.9	18.9	0.6	-4.3	-1.2
Allergy	2.8	6.5	14.7	-2.2	3.8	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.8	3.3	5.7	-1.8	1.1	-2.4
Wears glasses or contact lenses	2.8	3.2	3.6	1.7	-1.9	-1.8
Back pain experienced in last month	2.7	3.9	4.4	1.8	-2.0	2.1
Worry (Nagel 2018)	2.6	5.4	15.7	0.5	-4.0	-0.6
Fractured/broken bones in last 5 years	2.6	3.4	10.0	0.1	-3.2	0.3
Sensitivity / hurt feelings	2.5	4.3	11.8	-0.4	-3.4	-1.0
Migraine (self-reported)	2.5	3.1	4.0	-2.0	-1.4	-1.8
Hypertension (Self-reported)	2.5	6.9	11.6	0.7	3.4	2.9
High blood pressure	2.4	6.6	11.2	1.0	3.3	2.8
Hearing difficulty/problems with background noise	2.4	3.8	6.6	2.6	-1.3	1.8
Wheeze or whistling in the chest in last year	2.4	4.3	6.1	2.4	-2.5	1.1
Depressed Affect (Nagel 2018)	2.3	4.9	13.9	0.3	-3.7	-0.8
Neuroticism score	2.3	4.8	13.5	-0.4	-3.7	-0.8
Headache pain in last month	2.2	3.8	7.6	-2.8	-1.2	-1.6
Supplements: Calcium	2.2	2.4	5.0	-1.1	-0.9	-2.2
Seen doctor (GP) for nerves, anxiety, tension or depression	2.1	3.2	6.5	0.8	-2.6	-1.6
Ever depressed for a whole week	2.1	2.6	5.0	1.5	-2.2	-0.6
Vitamin and mineral supplements	2.0	2.8	5.6	0.6	1.6	2.4
Reason for reducing amount of alcohol drunk: Health precaution	2.0	2.3	5.0	-1.3	-0.2	-2.2
Mouth/teeth dental problems: Loose teeth	2.0	2.3	4.9	1.2	0.9	2.2
Tinnitus: Yes, now most or all of the time	2.0	2.3	3.3	1.8	-1.4	1.3
Number of operations (self-reported)	2.0	3.0	4.3	-1.1	-1.9	-2.1
Frequency of tenseness / restlessness in last 2 weeks	1.9	3.0	5.4	1.6	-2.3	1.1
Asthma	1.9	3.7	8.8	1.6	-3.0	0.1
Friendships satisfaction	1.9	2.3	4.8	2.2	0.5	1.4
Financial situation satisfaction	1.9	2.3	6.1	0.6	-2.5	-0.7
Irritability	1.9	3.3	8.9	0.9	-3.0	-0.3
Illnesses of siblings	1.8	2.5	5.5	-1.4	0.1	-2.4
Medication for cholesterol, blood pressure or diabetes	1.8	3.0	7.6	0.6	-2.8	-1.0
Exposure to tobacco smoke outside home	1.8	2.4	5.9	1.1	-2.4	-0.2
Mineral and other dietary supplements	1.8	2.4	3.6	-0.4	1.9	1.9
Ever taken oral contraceptive pill	1.8	2.0	3.8	-2.0	-1.2	-1.0
Hearing aid user	1.8	2.1	5.3	0.3	-2.3	-0.9
Pain experienced in last month	1.8	3.0	8.8	-0.3	3.0	-0.1
Severe depression (siblings)	1.7	1.9	4.7	1.0	-2.2	-0.2
Noisy workplace	1.7	2.1	5.5	0.9	0.3	2.4
Medication: Ibuprofen (e.g. Nurofen)	1.7	2.1	5.8	-0.5	-0.5	-2.4
Mood swings	1.7	3.1	9.2	0.2	-3.0	-0.2
Supplements: Fish oil (including cod liver oil)	1.7	2.3	4.2	1.2	-1.0	-2.0
Medication: Atorvastatin	1.7	2.0	3.2	-1.8	-0.8	-1.5
Illnesses of father: High blood pressure	1.7	2.0	4.0	2.0	-1.3	0.7
Neuroticism (2016)	1.6	2.3	5.3	-0.0	-2.3	-1.2
Allergy or Eczema	1.6	4.2	9.7	0.9	-3.1	-1.4
Other serious medical condition/disability diagnosed by doctor	1.6	2.1	6.2	-0.5	-0.0	-2.5
Systolic blood pressure, automated reading	1.6	4.6	6.8	0.9	2.6	2.5
Impedance of leg (left)	1.6	7.7	8.1	2.7	2.8	2.8
Financial difficulties in last 2 years	1.6	2.1	4.4	1.4	-2.1	-0.3
Mouth/teeth dental problems	1.6	2.5	5.8	-0.6	1.1	-2.4
Medication: Ramipril	1.6	2.0	5.4	0.4	2.3	0.7
Asthma (self-reported)	1.6	3.1	7.6	1.3	-2.8	-0.1
Ever smoked	1.6	2.9	4.2	2.0	0.6	2.0
Impedance of leg (right)	1.5	7.4	7.9	2.6	2.8	2.8
Hayfever, allergic rhinitis or eczema	1.5	3.2	7.5	1.2	-2.7	-0.7
Lung cancer (father)	1.5	1.7	2.2	1.5	-0.9	1.5
Medication: Paracetamol	1.5	2.5	7.0	0.5	-2.7	-0.4
Medication: Omeprazole	1.5	1.8	2.6	1.2	1.1	1.6
Osteoporosis (self-reported)	1.5	1.8	3.0	0.2	-1.5	-1.7
Medication: Omeprazole (e.g. Zanprol)	1.5	1.8	2.7	1.4	0.9	1.6
Fasting Glucose	1.4	1.7	4.3	0.2	-2.1	-0.8
HbA1C	1.4	1.5	3.1	0.8	-1.8	0.9
Ever used hormone-replacement therapy (HRT)	1.3	1.7	4.0	-2.0	0.2	-1.0
Diabetes (mother)	1.3	1.7	3.0	-0.6	-1.2	-1.7
Pack years adult smoking proportion	1.3	2.0	2.4	1.2	-1.5	1.5
Past tobacco smoking	1.3	2.4	4.4	-1.0	-1.4	-2.1
Father’s age at death	1.3	1.8	4.0	0.8	-2.0	-0.8
Worrier / anxious feelings	1.3	2.5	7.3	-0.3	-2.7	-0.2
Happiness	1.3	1.6	3.2	1.8	-0.3	1.2
Pulse wave reflection index	1.3	1.6	3.0	-1.2	-1.7	-0.4
Emphysema/chronic bronchitis	1.3	1.5	3.2	1.0	-0.5	1.8
Ever had bowel cancer screening	1.3	1.5	4.0	-0.7	0.1	-2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.3	1.5	2.3	-1.4	-0.7	-1.5
Frequency of depressed mood in last 2 weeks	1.2	1.7	4.3	0.9	-2.1	-0.4
Medication: Atenolol	1.2	1.5	2.4	-1.5	0.9	1.0
Nervous feelings	1.2	2.2	6.0	-0.5	-2.4	-0.5
Mouth/teeth dental problems: Dentures	1.2	2.1	5.6	-0.2	-0.8	2.4
Birth weight of first child	1.2	2.2	5.4	-0.6	-0.9	-2.3
Angina (self-reported)	1.2	1.5	3.1	1.2	-0.1	1.8
Suffer from ‘nerves’	1.2	1.9	4.2	1.0	-2.0	0.8
Medication: Aspirin	1.2	1.6	2.2	-1.2	1.2	-1.5
Knee pain experienced in last month	1.2	1.9	4.4	1.1	-0.3	2.1
Smoking status: Previous	1.2	1.8	2.6	0.8	1.5	1.6
Pack years of smoking	1.2	1.8	2.0	1.4	-1.2	1.4
Impedance of whole body	1.2	6.1	6.3	2.4	2.5	2.5
Bipolar Disorder (2018)	1.1	1.7	2.4	1.1	-1.5	-1.2
Body Mass Index (BMI) (2010)	1.1	1.5	3.3	-1.8	-0.1	-1.1
Supplements: Zinc	1.1	1.2	2.3	0.9	0.7	1.5
Taking other prescription medications	1.1	1.7	2.8	-0.5	-1.7	-1.4
Body mass index (BMI)	1.1	4.6	6.0	-2.3	-1.6	-2.5
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	2.8	-0.1	-1.7	-1.2
Pain all over the body in last month	1.1	1.2	2.9	-0.5	-1.7	-0.5
Worry too long after embarrassment	1.1	1.8	3.1	-1.1	-1.8	-1.0
Family relationship satisfaction	1.1	1.3	2.2	1.2	0.5	1.5
Leg pain on walking	1.1	1.4	2.9	0.3	1.1	1.7
Illnesses of siblings: Diabetes	1.1	1.4	2.0	1.4	-0.1	1.4
Eye problems/disorders: Cataract	1.1	1.2	2.4	0.1	-1.5	-1.1
Medication: Aspirin	1.1	1.4	2.8	-1.0	0.7	-1.7
Schizophrenia vs Biploar Disorder	1.0	1.3	2.3	-1.5	0.9	0.8
Systolic Blood Pressure	1.0	5.1	8.1	1.0	2.5	2.9
Chronotype (morning person)	1.0	2.3	5.5	1.1	-2.3	-0.2
Relative age of first facial hair	1.0	2.0	3.7	1.1	-1.9	-1.1
Ever had hysterectomy (womb removed)	1.0	1.1	2.7	1.6	-0.6	-0.6
Leg fat-free mass (left)	1.0	5.1	6.9	-2.6	-1.8	-2.2
Townsend deprivation index at recruitment	1.0	1.4	3.4	-0.7	-0.7	-1.8
Medication: Levothyroxine sodium	1.0	1.7	2.7	-1.6	-0.0	-1.6
Leg predicted mass (left)	1.0	5.0	7.0	-2.6	-1.8	-2.2
Waist circumference	1.0	3.5	5.6	-1.8	-1.4	-2.4
Had other major operations	1.0	1.3	3.0	0.8	-1.7	-0.4
Heart attack	1.0	1.3	2.7	0.6	0.9	1.6
Arm fat percentage (right)	1.0	3.8	6.7	-1.6	-1.5	-2.6
Eye problems/disorders: None of the above	1.0	1.2	2.6	0.3	1.6	0.9
Medication: Paracetamol	1.0	1.5	4.4	-0.3	-2.1	-0.2
Major Depression (MDD)	0.9	1.1	1.7	0.6	-1.3	1.1
Reaction Time	0.9	1.8	2.8	0.7	-1.7	-1.4
Age at First Birth	0.9	1.4	2.6	0.8	1.6	0.9
Cardiovascular Disease	0.9	3.0	4.6	0.2	2.1	2.1
Angina	0.9	1.1	2.3	1.0	-0.1	1.5
Current tobacco smoking	0.9	1.4	2.1	1.3	-1.4	0.7
Hip circumference	0.9	3.7	4.9	-2.1	-1.3	-2.2
Falls in the last year	0.9	1.2	2.8	0.6	-1.7	-0.5
Depression (self-reported)	0.9	1.0	2.0	-0.0	-1.4	-1.0
Arm fat mass (right)	0.9	3.8	5.9	-1.9	-1.5	-2.4
Hypothyroidism/myxoedema (self-reported)	0.9	1.7	3.7	-1.9	0.9	-0.9
Neck or shoulder pain in last month	0.9	1.2	3.5	0.4	-1.9	0.2
Mean time to correctly identify matches	0.9	1.7	2.0	1.2	-1.4	-1.4
Had major operations	0.9	1.1	1.7	0.7	-1.3	-1.0
Leg fat-free mass (right)	0.9	5.0	6.2	-2.5	-1.9	-2.3
Illnesses of father: None of the above (group 1)	0.9	1.2	1.7	1.3	-0.9	-1.0
Leg predicted mass (right)	0.9	5.0	6.0	-2.4	-1.9	-2.4
Arm fat mass (left)	0.9	3.6	5.5	-2.0	-1.2	-2.3
Medication: Blood pressure	0.9	1.7	3.0	-0.5	1.4	1.7
Medication: Lisinopril	0.9	1.2	2.7	-0.8	-0.3	1.7
Age started oral contraceptive pill	0.9	1.2	3.5	-0.2	1.9	0.2
Cholesterol lowering medication	0.9	1.4	2.3	-1.0	-0.9	-1.5
Alzheimer’s Disease (including proxy)	0.8	1.2	2.1	-1.5	-0.1	-1.2
Bipolar Disorder (2011)	0.8	0.8	1.7	0.0	-0.9	-1.3
Lupus	0.8	1.3	2.2	-0.1	-1.5	-1.2
Respiratory disease	0.8	1.8	3.1	1.1	-1.8	0.9
Average weekly fortified wine intake	0.8	1.0	2.1	-0.4	0.8	-1.5
Age when periods started (menarche)	0.8	2.0	4.6	1.2	-2.1	-0.1
Multivitamins +/- minerals	0.8	1.0	1.7	0.6	-1.0	-1.3
Stomach or abdominal pain in last month	0.8	1.0	2.9	-0.4	0.1	1.7
Diverticular disease/diverticulitis (self-reported)	0.8	1.0	1.8	-0.6	1.3	-0.8
Had menopause	0.8	1.0	2.4	0.5	1.5	0.6
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	1.7	0.1	-1.3	-1.2
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	1.4	1.2	1.1	0.3
Medication: Lansoprazole	0.8	0.9	2.7	-1.6	-0.1	-0.1
Tense / ‘highly strung’	0.8	1.3	2.5	1.0	-1.6	0.7
Glaucoma (self-reported)	0.8	1.0	2.6	0.2	-1.6	-0.5
Number of full brothers	0.8	1.0	2.5	0.6	-1.6	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.0	1.4	0.7	-1.1	-1.2
Medication: Ibuprofen	0.8	0.9	2.1	-0.6	-0.6	-1.4
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	1.6	-1.3	0.9	-0.6
Supplements: Vitamin C	0.8	0.9	2.4	0.5	-1.6	-0.2
Whole body fat-free mass	0.8	4.3	5.3	-2.3	-1.6	-2.3
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	2.0	1.2	-0.7	1.4
Whole body water mass	0.8	4.3	5.2	-2.3	-1.6	-2.2
Basal metabolic rate	0.8	4.3	5.5	-2.3	-1.5	-2.2
Heart disease (siblings)	0.8	1.0	2.4	0.2	-0.8	1.6
Schizophrenia (2018)	0.7	1.4	2.2	-1.2	0.8	-1.5
Smoking Status	0.7	1.7	2.6	1.6	-0.6	1.5
Average weekly spirits intake	0.7	0.9	2.5	-0.1	-0.5	1.6
Number of incorrect matches in round	0.7	1.1	2.0	-0.8	1.4	-0.8
Medication: Ventolin 100micrograms inhaler	0.7	0.9	2.2	0.5	-1.5	0.6
Birth weight	0.7	1.5	4.2	0.4	0.4	-2.0
Comparative body size at age 10	0.7	1.9	3.1	-1.6	-1.8	-0.1
Shortness of breath walking on level ground	0.7	0.8	1.5	1.0	-1.2	0.3
Qualifications: College or University degree	0.7	2.3	4.5	-0.9	-1.2	-2.1
Comparative height size at age 10	0.7	3.9	9.0	-1.4	3.0	1.0
Arm fat percentage (left)	0.7	2.9	4.8	-1.6	-1.1	-2.2
Eye problems/disorders: Glaucoma	0.7	0.9	2.5	0.2	-1.6	-0.1
Medication: Bendroflumethiazide	0.7	1.1	1.9	-0.7	1.0	1.4
Heart attack/myocardial infarction (self-reported)	0.7	0.9	1.8	0.2	0.9	1.4
Ovarian Cancer	0.6	0.7	2.1	-0.4	0.2	1.4
BMI	0.6	3.2	3.7	-1.8	-1.9	-1.7
Lung FEV1/FVC ratio	0.6	3.0	7.8	-2.8	-0.3	-1.0
Medication for hormone replacement therapy	0.6	0.7	1.2	-0.4	-1.1	0.8
Medication: Metformin	0.6	0.9	2.0	-0.8	1.4	0.2
Fed-up feelings	0.6	1.1	3.1	-0.0	-1.8	-0.6
High blood pressure (mother)	0.6	0.9	1.3	-1.2	0.3	1.1
Weight	0.6	2.8	3.8	-2.0	-0.9	-1.9
Trunk fat-free mass	0.6	3.3	4.6	-1.8	-1.4	-2.2
Pulse rate	0.6	0.9	1.2	1.1	1.1	0.7
Prospective memory result	0.6	0.7	0.9	0.5	-0.9	-1.0
Pulse wave Arterial Stiffness index	0.6	0.8	0.8	0.8	-0.9	0.9
Impedance of arm (left)	0.6	2.7	3.7	1.9	1.6	1.4
Length of working week for main job	0.6	0.6	1.4	0.4	-0.5	1.2
Exposure to tobacco smoke at home	0.6	0.7	1.9	0.2	-1.4	0.2
Breastfed as a baby	0.6	0.7	1.6	1.3	0.7	0.1
Peak expiratory flow (PEF)	0.6	1.5	3.7	0.3	1.9	0.8
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	1.6	0.8	-1.2	0.4
Chronic bronchitis/emphysema (mother)	0.6	0.7	1.2	-1.1	-0.2	-0.8
Number of children fathered	0.6	0.6	1.9	0.1	0.1	1.4
Medication: Allopurinol	0.6	0.8	2.1	1.5	0.3	0.2
Medication: Seretide 50 evohaler	0.6	0.7	1.9	0.3	0.3	1.4
Whole body fat mass	0.6	2.5	4.4	-1.7	-0.3	-2.1
Pulse rate, automated reading	0.6	1.8	3.2	1.0	1.8	1.1
Chest pain or discomfort	0.6	0.9	2.6	0.4	0.1	1.6
Guilty feelings	0.6	0.9	1.9	1.0	-1.4	0.1
Arm fat-free mass (left)	0.6	3.1	4.7	-2.2	-1.0	-1.9
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.6	-0.5	1.3	-0.2
Basal cell carcinoma (self-reported)	0.6	0.8	1.3	0.8	0.5	-1.1
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	1.9	0.6	-1.4	-0.0
Bipolar Disorder or Schizophrenia	0.5	1.3	3.7	-0.3	-0.3	-1.9
Depression (Nagel 2018)	0.5	0.8	1.9	0.5	-1.4	-0.5
Mean Putamen Volume	0.5	0.6	0.8	0.9	0.9	0.3
Ulcerative Colitis	0.5	0.7	1.0	-0.6	1.0	0.9
Trunk fat mass	0.5	2.0	3.3	-1.6	0.1	-1.8
Illnesses of mother	0.5	0.6	1.3	1.2	0.6	-0.1
Trunk predicted mass	0.5	3.1	4.2	-1.7	-1.4	-2.1
Loud music exposure frequency	0.5	0.5	1.5	-0.3	-1.2	-0.2
High blood pressure (siblings)	0.5	0.8	1.1	1.0	0.4	1.1
Arm fat-free mass (right)	0.5	2.5	4.5	-2.1	-0.6	-1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	0.8	0.9	-0.7	0.7
Arm predicted mass (right)	0.5	2.6	4.6	-2.1	-0.7	-1.7
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.7	1.3	-0.3	-0.8	-1.1
Average weekly champagne plus white wine intake	0.5	0.7	1.4	-0.7	-0.5	-1.2
Average weekly beer plus cider intake	0.5	0.8	1.9	1.4	0.6	0.3
Diastolic blood pressure, automated reading	0.5	1.5	2.7	0.2	1.6	1.3
Arm predicted mass (left)	0.5	2.7	4.8	-2.2	-0.7	-1.7
Irritable Bowel Disease (IBD)	0.4	1.0	1.5	-1.2	0.5	1.1
Ulcerative Colitis (UC)	0.4	0.7	0.8	-0.8	0.9	0.8
Primary Biliary Cirrhosis	0.4	0.6	1.1	-0.2	0.9	1.0
Schizophrenia (2014)	0.4	1.0	2.7	-0.4	-0.3	-1.6
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	1.0	0.4	-1.0	0.1
Diabetes (father)	0.4	0.5	1.6	0.2	-1.3	-0.1
Trunk fat percentage	0.4	1.5	2.8	-1.3	0.4	-1.7
Maternal smoking around birth	0.4	0.6	1.5	-1.2	0.4	0.3
Supplements: Glucosamine	0.4	0.6	1.3	0.3	-0.5	-1.1
Chronic bronchitis/emphysema (father)	0.4	0.5	1.4	0.1	0.2	1.2
Impedance of arm (right)	0.4	1.7	4.0	2.0	0.7	0.7
Hair/balding pattern: Pattern 3	0.4	0.6	0.9	0.7	0.7	1.0
Number of live births	0.4	0.5	0.9	-0.1	-0.8	-0.9
Blood clot in the leg (DVT)	0.4	0.5	1.4	0.3	-1.2	0.1
Gout (self-reported)	0.4	0.5	1.4	1.2	0.4	-0.1
Pulse wave peak to peak time	0.4	0.5	0.6	-0.6	0.8	-0.7
Heart disease (mother)	0.4	0.4	1.0	-0.3	1.0	0.4
Leg fat mass (right)	0.4	1.4	2.2	-1.5	-0.5	-1.3
Age at last live birth	0.4	0.6	1.2	0.3	1.1	0.6
Commuting to job workplace: Car/motor vehicle	0.4	0.5	0.8	0.8	-0.9	0.2
Illnesses of father: Heart disease	0.4	0.5	0.8	-0.9	0.7	-0.6
Loneliness, isolation	0.4	0.6	1.1	0.7	-0.4	1.0
Commuting to job workplace: Walk	0.4	0.4	0.5	-0.5	0.7	0.7
Smoking status: Current	0.4	0.6	1.0	0.7	-1.0	0.6
Alcohol drinker status: Never	0.4	0.5	1.0	-1.0	0.1	-0.6
Risk taking	0.4	0.6	1.1	0.0	-1.1	0.7
Myopia	0.4	0.6	1.2	0.4	-1.1	-0.7
Alcohol drinker status: Previous	0.4	0.5	1.3	-1.1	-0.2	0.3
Leg fat mass (left)	0.4	1.4	2.0	-1.4	-0.5	-1.3
Crohns Disease (2012)	0.3	0.4	0.9	-0.4	-0.9	0.5
Blood Eosinophil Count	0.3	2.3	5.9	-0.3	-2.4	1.0
Blood White Count	0.3	2.4	5.7	-2.4	1.0	0.8
Waist Hip Ratio (WHR)	0.3	1.2	2.1	0.4	-1.5	-1.2
Hypothyroidism (self reported)	0.3	0.7	1.3	-1.2	0.2	-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.5	0.7	0.6	-0.8	0.5
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	0.8	-0.5	-0.9	-0.0
Qualifications: CSEs or equivalent	0.3	0.5	0.9	-0.4	-0.9	0.6
Medication: Simvastatin	0.3	0.5	0.8	-0.1	-0.9	-0.8
Alcohol intake versus 10 years previously	0.3	0.5	1.0	0.5	-0.6	-1.0
Body fat percentage	0.3	1.2	2.4	-1.1	0.1	-1.6
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	1.3	-0.0	-1.1	0.8
Medication for cholesterol	0.3	0.5	1.1	0.4	0.5	-1.0
Breast cancer (self-reported)	0.3	0.4	0.6	0.8	0.3	0.7
Osteoarthritis (self-reported)	0.3	0.5	1.3	-0.1	0.1	-1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.2	-0.1	-0.7	-1.1
Commuting to job workplace: Public transport	0.3	0.3	0.8	-0.2	-0.9	-0.3
Pain type(s) experienced in last month: Hip pain	0.3	0.3	0.6	0.8	-0.2	0.5
Commuting to job workplace: Cycle	0.3	0.4	0.8	-0.9	-0.2	-0.5
Crohns Disease (2017)	0.2	0.4	0.5	-0.7	-0.7	0.6
Tanning	0.2	2.9	4.8	2.2	-1.1	1.7
Medication: Co-codamol	0.2	0.3	0.5	-0.6	-0.7	0.0
Hand grip strength (right)	0.2	0.5	0.8	-0.5	0.7	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.1	-1.0	0.1	0.3
Sitting height	0.2	1.4	4.2	0.2	2.0	0.3
Qualifications: None of the above	0.2	0.4	0.8	0.2	0.9	0.6
Time employed in main current job	0.2	0.2	0.5	-0.1	-0.7	-0.0
Hair/balding pattern: Pattern 4	0.2	0.4	0.8	-0.4	0.9	-0.5
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.3	0.4	-0.6	0.3
Health satisfaction	0.2	0.2	0.3	0.4	0.5	0.5
Number of full sisters	0.2	0.2	0.5	0.2	0.1	0.7
Handedness (chirality/laterality): Left-handed	0.2	0.3	0.4	0.6	0.2	0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.4	-0.6	0.1	-0.5
High cholesterol (Self-reported)	0.2	0.3	0.7	-0.9	0.1	-0.4
Unable to work because of sickness or disability	0.2	0.2	0.6	-0.1	-0.8	-0.1
Intelligence (Savage-Jansen 2018)	0.1	0.5	1.1	1.1	0.5	0.1
Coronary Artery Disease (CAD)	0.1	0.2	0.4	-0.2	0.7	-0.1
LDL Cholesterol	0.1	0.1	0.1	0.4	0.3	0.3
Rheumatoid Arthritis	0.1	0.2	0.4	-0.2	0.4	0.7
Triglycerides	0.1	0.2	0.4	-0.3	-0.2	0.6
Type 2 Diabetes (T2D) (2012)	0.1	0.2	0.2	0.2	-0.5	-0.4
Blood Red Count	0.1	0.7	2.1	1.5	-0.1	0.3
Heel T-Score	0.1	0.7	1.6	0.8	1.3	-0.1
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.4	-0.2	-0.6	-0.6
Lung FVC	0.1	0.3	0.7	0.8	-0.2	-0.3
Hand grip strength (left)	0.1	0.3	0.7	0.2	0.2	-0.9
Number of treatments/medications taken	0.1	0.2	0.3	-0.6	0.1	-0.4
Relative age voice broke	0.1	0.1	0.1	0.3	-0.4	-0.1
Serious illness, injury or assault to yourself	0.1	0.1	0.3	-0.1	-0.6	0.0
Alcohol usually taken with meals	0.1	0.1	0.3	-0.2	0.3	-0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.5	-0.7	-0.0	0.2
Diabetes (self-reported)	0.1	0.1	0.4	-0.6	0.0	0.1
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	0.5	-0.7	0.0	-0.6
Qualifications: A levels/AS levels or equivalent	0.1	0.3	0.4	0.7	-0.4	-0.5
Medication: Cholesterol lowering	0.1	0.2	0.3	0.5	-0.6	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	0.3	-0.3	0.6	-0.4
Standing height	0.1	0.7	1.7	0.4	1.3	0.5
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.2	0.3	0.0	0.5
Leg fat percentage (right)	0.1	0.3	0.5	-0.7	0.1	-0.6
Medication for pain relief, constipation, heartburn	0.1	0.1	0.3	0.2	-0.2	0.6
Alcohol intake frequency.	0.1	0.2	0.2	-0.5	-0.1	-0.5
Overall health rating	0.1	0.1	0.3	-0.0	-0.5	0.3
Average weekly red wine intake	0.1	0.2	0.4	-0.2	0.3	0.6
Long-standing illness, disability or infirmity	0.1	0.2	0.2	-0.5	-0.2	0.5
Diabetes diagnosed by doctor	0.1	0.2	0.5	-0.7	0.5	-0.2
Qualifications: nursing, teaching	0.1	0.1	0.2	0.4	0.3	-0.3
Medication: Gliclazide	0.1	0.2	0.2	-0.4	-0.4	-0.4
Number of self-reported non-cancer illnesses	0.1	0.2	0.3	-0.0	-0.4	-0.5
Mother’s age at death	0.1	0.1	0.2	-0.4	0.0	-0.5
Leg fat percentage (left)	0.1	0.3	0.5	-0.7	0.1	-0.6
Verbal and Numeric Reasoning (VNR)	0.0	0.0	0.0	-0.2	0.1	-0.2
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0
Height	0.0	0.8	2.0	0.2	1.4	0.6
Hair Pigment	0.0	0.4	0.7	-0.5	0.6	0.8
Tinnitus: Yes, but not now, but have in the past	0.0	0.0	0.1	-0.3	-0.0	-0.2
Hair/balding pattern: Pattern 2	0.0	0.0	0.0	-0.1	0.2	0.1
Forced vital capacity (FVC)	0.0	0.0	0.0	-0.2	0.1	0.0
Fluid intelligence score	0.0	0.0	0.0	-0.1	0.1	-0.2
Forced vital capacity (FVC), Best measure	0.0	0.2	0.4	-0.4	0.6	-0.2
Age at first live birth	0.0	0.0	0.0	0.2	0.1	0.2

Hub : Genes

USP30-AS1

Models

Trait associations