Hub : Genes

USP37

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0550	0.0220	1.3e-04	0.028	NA	0.017	NA	0.029	2.2e-03	NA	1.4e-02	NA	2.0e-03
2	GTEx	Artery Aorta	0.0790	0.0390	5.6e-03	0.049	NA	0.002	NA	0.045	1.1e-03	NA	2.5e-01	NA	1.7e-03
3	GTEx	Brain Cerebellum	0.1310	0.0650	2.7e-03	0.163	NA	0.079	NA	0.147	1.5e-05	NA	2.5e-03	NA	4.2e-05
4	GTEx	Breast Mammary Tissue	0.1970	0.0830	1.9e-03	0.016	NA	-0.004	NA	0.009	4.9e-02	NA	5.7e-01	NA	1.1e-01
5	GTEx	Breast Mammary Tissue (Male)	0.0790	0.0714	1.4e-01	-0.009	NA	-0.005	NA	-0.011	5.8e-01	NA	4.3e-01	NA	7.3e-01
6	GTEx	Breast Mammary Tissue (Female)	0.1567	0.1056	8.3e-02	0.001	NA	-0.002	NA	-0.009	2.9e-01	NA	3.7e-01	NA	8.3e-01
7	GTEx	Cells Transformed fibroblasts	0.1090	0.0380	9.8e-06	0.057	NA	0.072	NA	0.058	4.1e-05	NA	4.5e-06	NA	3.4e-05
8	GTEx	Esophagus Mucosa	0.1040	0.0420	3.8e-05	0.066	NA	0.062	NA	0.053	3.2e-05	NA	5.6e-05	NA	1.8e-04
9	GTEx	Nerve Tibial	0.0632	0.0302	1.6e-03	0.057	NA	0.043	NA	0.054	7.3e-05	NA	4.9e-04	NA	1.1e-04
10	GTEx	Pancreas	0.0950	0.0490	7.1e-03	0.007	NA	-0.005	NA	0.005	1.6e-01	NA	5.7e-01	NA	1.8e-01
11	GTEx	Skin Not Sun Exposed Suprapubic	0.1080	0.0420	9.0e-05	0.006	NA	0.065	NA	0.029	1.4e-01	NA	1.9e-04	NA	1.0e-02
12	GTEx	Spleen	0.2550	0.1120	1.5e-03	0.051	NA	0.022	NA	0.065	1.9e-02	NA	9.2e-02	NA	9.4e-03
13	GTEx	Thyroid	0.0930	0.0320	2.6e-06	0.077	NA	0.057	NA	0.061	1.7e-06	NA	3.3e-05	NA	1.8e-05
14	METSIM	Adipose	0.0429	0.0163	1.4e-05	0.017	0.024	0.021	0.018	0.020	1.3e-03	1.5e-04	3.6e-04	0.00086	5.1e-04
15	NTR	Blood	0.0112	0.0071	7.5e-03	0.010	0.007	0.002	0.006	0.005	3.3e-04	1.7e-03	8.7e-02	0.00330	7.4e-03
16	TCGA	Prostate Adenocarcinoma	0.0232	0.0161	1.2e-03	0.024	0.020	0.020	NA	0.018	1.4e-03	3.2e-03	3.2e-03	NA	4.7e-03
17	TCGA	Thyroid Carcinoma	0.0480	0.0340	2.5e-05	0.034	0.045	0.023	NA	0.036	2.6e-04	3.4e-05	2.5e-03	NA	1.9e-04
18	TCGA	Uterine Corpus Endometrial Carcinoma	0.0840	0.0590	8.7e-03	0.018	0.006	-0.011	NA	-0.009	9.9e-02	2.2e-01	9.6e-01	NA	7.3e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Bipolar Disorder (2018)	0.2	0.3	0.7	0.3	0.0	-0.7	0.6	0.1	0.5	0.3	0.5	-0.0	0.7	-0.4	0.5	0.5	0.9	0.5	0.6	0.5	0.7
Bipolar Disorder or Schizophrenia	0.2	0.5	1.1	1.1	0.2	-1.1	0.8	0.4	0.3	0.4	0.1	0.3	0.9	0.1	0.7	0.8	0.9	0.5	1.0	0.8	0.9
Depressed Affect (Nagel 2018)	0.4	0.8	1.3	0.6	1.0	-0.8	1.0	0.5	0.9	0.6	1.0	1.0	1.1	0.4	1.2	0.9	0.8	0.9	0.6	0.9	1.0
Depression (Nagel 2018)	0.4	0.7	3.2	0.8	0.5	-0.9	0.9	0.1	-0.1	0.6	1.8	0.6	0.6	0.5	0.4	0.9	0.1	0.9	1.0	1.0	1.1
Intelligence (Savage-Jansen 2018)	0.4	1.4	6.8	-1.2	-0.8	0.5	0.2	-0.1	2.6	-0.9	0.6	-1.1	1.1	-1.4	1.6	-0.3	0.8	-1.7	-1.4	-0.9	-0.9
Neuroticism (Nagel 2018)	0.2	0.4	0.9	-0.6	-0.4	0.7	-0.0	-0.7	1.0	-0.6	-0.1	-0.7	0.0	0.0	0.4	-0.7	-0.8	-0.7	-0.9	-0.6	-0.6
Schizophrenia (2018)	0.2	0.3	1.3	1.2	0.2	-0.8	0.6	0.5	0.0	0.3	-0.4	0.4	0.6	0.2	0.5	0.7	0.5	0.2	0.9	0.7	0.7
Schizophrenia vs Biploar Disorder	0.6	0.8	2.9	-0.6	-0.6	0.9	-1.1	-0.5	-0.8	-0.6	-1.7	-0.6	-1.2	-0.6	-1.0	-1.0	-1.2	-0.5	-0.7	-0.7	-0.8
Worry (Nagel 2018)	0.3	0.6	1.3	-0.9	-0.8	0.8	0.1	-0.8	1.2	-0.6	-0.1	-1.1	-0.1	0.3	0.4	-1.0	-1.0	-1.0	-1.1	-0.8	-0.9
Alzheimer’s Disease (in mother)	1.9	2.2	4.5	-1.4	-1.3	1.8	-1.2	-0.8	-0.6	-2.1	-1.4	-1.3	-1.6	-0.3	-1.3	-2.0	-1.8	-1.5	-1.6	-1.6	-1.7
Alzheimer’s Disease (in father)	1.1	1.2	2.5	1.1	1.0	-1.2	0.9	1.5	-0.2	0.3	1.6	1.3	0.7	0.9	0.3	1.2	0.6	1.4	1.3	1.3	1.3
Alzheimer’s Disease (including proxy)	0.2	0.3	1.7	-0.3	-0.0	0.5	0.1	0.5	-0.7	-1.3	-0.0	0.0	-0.7	0.1	-0.8	-0.8	-1.0	-0.5	-0.5	-0.2	-0.3
Crohns Disease (2017)	0.8	1.8	3.5	1.9	0.2	-1.5	-0.5	-1.6	-1.7	1.5	1.0	0.4	0.4	-1.2	-0.3	1.8	0.7	1.7	1.9	1.8	1.7
Irritable Bowel Disease (IBD)	0.7	1.6	10.6	0.6	-0.5	-0.4	-2.3	-1.1	-2.2	0.5	0.3	-0.4	-0.8	-3.2	-1.3	1.1	0.1	1.0	0.9	0.6	0.6
Ulcerative Colitis (UC)	0.9	1.6	10.9	-0.8	-1.1	0.7	-2.6	-0.0	-1.3	-0.5	-0.4	-1.1	-1.4	-3.3	-1.5	-0.1	-0.4	-0.3	-0.4	-0.8	-0.7
Major Depression (MDD)	2.2	2.7	4.6	1.9	1.6	-2.0	2.0	1.7	-0.4	1.7	1.0	1.7	1.4	1.7	0.7	1.6	0.7	2.2	2.1	2.0	2.0
Reaction Time	0.2	0.3	1.9	0.6	0.2	-0.5	0.3	-0.3	-0.7	1.1	0.2	0.4	-0.2	1.4	-0.5	0.6	0.1	0.2	0.6	0.4	0.4
Verbal and Numeric Reasoning (VNR)	0.6	1.4	3.4	-1.3	-1.3	1.1	-0.3	-0.8	1.9	-1.5	0.2	-1.5	0.3	-0.6	0.9	-1.1	-0.3	-1.8	-1.6	-1.4	-1.3
Breast Cancer	0.4	1.0	3.6	-0.6	-1.2	0.8	-1.7	0.0	-0.7	0.2	-1.5	-1.0	-0.9	-1.9	-1.1	-0.6	-0.0	-1.5	-0.5	-0.7	-0.7
Ovarian Cancer	1.7	2.2	4.0	1.8	1.8	-1.9	1.2	0.9	-0.0	1.6	0.6	1.8	1.3	0.9	1.0	2.0	0.9	1.6	1.9	1.9	1.8
Prostate Cancer	1.3	1.9	6.6	0.7	1.1	-1.0	1.7	0.6	2.6	1.0	1.0	0.6	2.3	1.2	2.4	1.1	2.1	0.1	0.2	0.7	0.7
Age at First Birth	2.7	3.9	6.0	1.9	2.3	-2.1	2.4	2.1	1.5	2.3	1.3	2.1	2.4	1.4	2.2	2.1	2.0	1.1	1.7	2.0	2.1
Bipolar Disorder (2011)	0.5	0.5	2.2	-0.0	-1.2	0.2	-0.3	-1.2	0.1	0.4	1.0	-1.0	0.0	-1.5	0.3	-0.1	-0.1	-0.7	-0.2	-0.2	-0.1
Body Mass Index (BMI) (2010)	5.3	7.3	14.6	3.4	3.0	-2.9	2.0	3.0	-0.9	3.8	2.4	3.4	1.8	1.0	1.3	2.9	1.8	2.9	3.1	3.2	3.2
Coronary Artery Disease (CAD)	0.1	0.1	1.1	0.2	-0.5	-0.2	-0.0	-0.5	0.1	0.4	1.0	-0.5	0.1	0.2	-0.2	0.3	0.3	-0.3	0.2	0.1	0.1
Crohns Disease (2012)	0.4	0.6	2.5	-0.1	-1.1	-0.0	-1.1	-1.3	-1.0	-0.4	0.3	-0.9	-0.4	-1.6	-0.7	0.3	-0.6	0.5	0.2	0.2	0.1
Mean Putamen Volume	0.1	0.1	0.7	-0.2	0.0	0.2	-0.2	-0.0	0.6	0.2	-0.4	-0.0	0.2	0.2	0.7	-0.1	-0.1	-0.8	-0.4	-0.2	-0.1
Fasting Glucose	0.2	0.2	1.2	0.4	0.6	-0.5	-0.3	0.4	-0.3	-0.2	0.1	0.7	0.2	0.0	-0.1	0.6	0.2	1.1	0.6	0.6	0.5
HbA1C	0.7	0.7	2.0	0.9	0.9	-0.8	0.4	1.0	0.2	0.9	1.3	1.0	0.6	1.4	0.6	0.8	0.5	0.8	0.7	0.9	0.8
HDL Cholesterol	1.1	1.9	4.8	1.6	1.2	-1.5	1.3	1.7	-0.2	0.6	1.3	1.2	1.0	1.9	0.3	1.4	1.1	2.2	1.5	1.5	1.4
LDL Cholesterol	0.8	1.3	4.7	-1.3	-0.6	1.2	-1.7	0.4	-0.1	-1.1	-0.7	-0.6	-1.3	-2.2	-0.6	-1.0	-0.3	-1.2	-1.2	-1.4	-1.3
Lupus	0.2	0.3	0.8	0.7	0.2	-0.6	0.7	-0.1	0.9	0.4	0.9	0.2	0.7	0.8	0.7	0.5	0.3	0.5	0.4	0.5	0.3
Neuroticism (2016)	0.5	0.8	3.1	-1.0	-1.1	0.8	-0.2	-1.8	1.0	-0.1	-0.6	-1.0	-0.1	-0.9	-0.1	-1.0	-0.5	-1.2	-0.9	-0.8	-0.8
Primary Biliary Cirrhosis	2.4	3.5	11.5	-1.9	-2.3	1.7	-1.8	-2.3	1.2	-1.1	-1.9	-2.4	-0.6	-3.4	-0.1	-1.3	-1.1	-2.1	-2.1	-1.9	-1.9
Rheumatoid Arthritis	0.7	0.9	3.4	0.2	0.6	-0.7	1.0	1.0	1.4	-0.2	1.3	0.3	1.3	1.9	1.1	0.8	1.1	1.0	0.3	0.5	0.4
Schizophrenia (2014)	0.2	0.4	1.3	1.1	0.2	-0.9	0.8	0.4	0.0	0.3	-0.7	0.2	0.7	0.2	0.6	0.7	0.6	0.2	0.9	0.8	0.8
Triglycerides	3.4	5.6	13.8	-2.9	-2.0	2.8	-2.2	-1.8	1.8	-1.4	-1.6	-2.2	-1.0	-3.3	-0.1	-2.4	-1.2	-3.7	-3.1	-3.0	-2.8
Type 2 Diabetes (T2D) (2012)	0.6	0.7	1.6	-0.8	-1.1	0.7	-1.1	-0.7	-0.7	-0.3	-0.2	-1.2	-0.9	-0.9	-0.6	-0.9	-1.0	-0.9	-0.5	-0.7	-0.6
Ulcerative Colitis	1.5	2.2	14.7	-0.5	-1.3	0.8	-2.8	-0.2	-1.7	-0.6	0.6	-1.0	-1.7	-3.8	-2.0	-0.1	-0.9	-0.5	-0.4	-0.8	-0.8
Blood Eosinophil Count	0.6	4.6	8.7	-2.3	-2.4	2.7	-1.6	-1.3	0.3	-2.6	-2.3	-2.4	-1.5	-0.6	-1.0	-3.0	-2.1	-2.2	-2.8	-2.5	-2.7
Blood Platelet Count	4.3	49.3	116.6	10.8	5.4	-8.4	2.5	4.8	-5.4	9.9	6.8	6.7	3.3	-0.3	0.4	9.4	4.4	6.0	10.0	9.3	9.1
Blood Red Count	10.5	101.0	164.9	-12.2	-10.7	11.7	-8.2	-10.3	3.6	-11.2	-8.1	-11.6	-6.6	-6.4	-3.3	-11.5	-7.5	-12.8	-12.8	-12.1	-12.2
Blood White Count	0.9	6.8	33.3	-0.0	1.9	-0.4	3.4	2.2	5.8	0.7	1.6	1.2	3.2	4.4	4.8	0.2	2.6	-1.7	-1.1	0.2	-0.0
Heel T-Score	0.2	1.4	13.9	0.9	-1.1	-0.4	-1.2	-1.0	-0.1	0.7	0.9	-0.6	0.1	-3.7	0.2	0.8	1.8	-0.1	0.5	0.3	0.5
BMI	4.3	24.9	34.3	5.7	5.3	-5.8	5.3	5.0	0.0	5.7	5.5	5.6	4.3	2.5	2.9	5.5	4.1	4.9	5.8	5.9	5.8
Height	7.8	151.1	313.3	-17.1	-11.7	14.9	-7.1	-8.7	9.9	-14.5	-7.4	-13.9	-5.5	-2.8	-0.2	-15.0	-8.6	-15.0	-17.7	-16.0	-16.0
Waist Hip Ratio (WHR)	1.2	5.4	23.8	-2.4	-2.0	2.0	-3.0	-1.8	1.2	-2.0	-2.6	-2.5	-1.2	-4.9	-0.2	-1.3	-0.3	-3.1	-2.4	-2.1	-2.3
Systolic Blood Pressure	0.3	1.4	6.5	0.8	0.9	-1.1	-0.0	0.7	1.0	1.0	1.6	0.8	1.0	-2.5	1.2	1.6	1.5	0.2	0.8	0.8	1.0
Smoking Status	0.1	0.3	0.5	0.5	0.5	-0.5	0.5	0.4	0.6	0.5	0.3	0.5	0.7	-0.6	0.7	0.6	0.5	0.6	0.4	0.5	0.4
Allergy or Eczema	2.9	7.7	12.7	3.3	3.0	-3.2	1.7	2.4	-1.0	3.0	2.9	3.4	2.0	-0.7	1.1	3.5	1.7	3.5	3.5	3.6	3.5
Cardiovascular Disease	1.5	5.1	18.7	1.4	1.9	-2.3	1.8	1.7	2.3	2.5	4.3	1.6	2.6	-0.2	2.9	2.7	2.8	0.3	1.7	2.0	2.1
Hypothyroidism (self reported)	3.5	8.1	13.2	3.5	3.6	-3.0	2.9	2.8	0.9	3.6	2.6	3.5	2.5	1.8	2.2	3.1	2.5	2.2	2.8	3.2	3.1
Respiratory disease	0.4	1.0	1.9	1.4	0.9	-1.1	-0.1	0.9	-1.0	0.5	1.4	1.2	0.3	-0.3	-0.1	1.2	0.1	1.1	1.3	1.2	1.2
Type 2 Diabetes (T2D) (2018)	0.1	0.3	1.2	0.2	-0.4	0.0	-0.6	-0.3	-1.1	0.1	0.7	-0.3	-0.5	-0.9	-0.8	0.1	-0.6	0.2	0.3	0.1	0.1
Lung FEV1/FVC ratio	0.5	2.6	6.2	0.9	1.6	-1.6	1.5	1.3	2.3	1.6	1.1	1.3	2.4	-0.5	2.5	1.9	2.5	0.6	0.9	1.1	1.3
Lung FVC	1.1	5.8	18.9	2.3	2.4	-2.5	2.7	2.7	-1.1	2.0	0.7	2.7	1.2	4.3	0.4	1.9	1.8	3.1	2.8	2.5	2.6
Neuroticism	0.5	1.2	2.4	-1.5	-0.8	1.2	-0.2	-1.0	1.1	-1.4	0.1	-1.2	-0.5	0.9	0.3	-1.4	-1.3	-1.2	-1.5	-1.3	-1.3
Chronotype (morning person)	2.6	6.0	10.6	-3.0	-2.7	2.7	-2.2	-2.5	1.1	-2.0	-2.6	-3.0	-1.4	-2.7	-0.5	-2.5	-1.4	-3.3	-3.1	-2.8	-2.7
Hair Pigment	0.0	0.6	2.7	0.9	0.3	-0.0	0.5	0.3	-1.6	0.5	0.3	0.4	-1.1	1.4	-1.2	-0.4	-0.9	0.1	0.4	0.4	0.2
Tanning	0.5	5.6	14.3	2.4	2.2	-2.9	2.5	2.0	-0.7	1.8	0.7	2.5	2.0	2.2	1.2	2.5	2.0	3.8	3.0	2.9	3.0
Hand grip strength (left)	1.0	2.6	5.7	-2.0	-1.2	1.8	-0.2	-1.2	2.3	-1.6	-2.1	-1.6	-0.1	0.3	0.9	-1.9	-0.1	-1.8	-2.4	-1.9	-1.9
Number of treatments/medications taken	1.9	3.3	8.3	1.6	2.1	-2.0	1.9	1.9	0.9	1.9	2.9	1.9	1.9	0.8	1.7	2.2	1.5	0.8	1.8	2.0	2.0
Average weekly spirits intake	0.8	1.1	2.9	1.1	0.4	-1.2	1.2	0.9	-0.3	1.2	0.8	0.6	0.7	1.7	0.4	1.1	0.0	1.5	1.2	1.2	1.2
Sensitivity / hurt feelings	0.4	0.7	1.5	-0.6	-0.7	0.9	-0.7	-0.8	-0.1	-0.8	0.1	-1.0	-0.8	0.6	-0.4	-0.9	-1.2	-1.2	-0.9	-0.8	-0.9
Frequency of depressed mood in last 2 weeks	0.2	0.2	1.9	-0.4	0.3	-0.1	0.3	0.6	0.6	0.2	1.4	0.1	0.3	0.4	0.5	0.2	0.5	-0.2	-0.1	0.0	0.1
Hearing difficulty/problems: Yes	0.3	0.5	2.2	0.1	-0.1	-0.7	1.2	0.1	-0.4	1.5	0.4	0.0	0.2	1.5	0.0	0.5	0.3	-0.2	0.7	0.6	0.7
Relative age of first facial hair	1.2	2.5	5.2	2.1	1.6	-1.7	0.7	1.8	-1.3	2.0	-0.2	1.8	0.6	-0.8	0.2	1.7	1.3	2.3	2.1	1.9	1.9
Other serious medical condition/disability diagnosed by doctor	1.1	1.4	4.7	0.2	1.2	-0.9	1.5	0.8	1.6	1.1	2.2	0.9	1.5	1.5	1.7	1.0	0.9	0.0	0.5	0.7	0.7
Ever used hormone-replacement therapy (HRT)	0.6	0.8	2.2	-0.5	-0.6	0.8	-0.5	-0.0	-1.3	-1.1	-1.0	-0.3	-1.1	-0.1	-1.5	-1.1	-1.4	0.0	-0.5	-0.8	-0.8
Ever had hysterectomy (womb removed)	1.7	2.0	4.7	-1.7	-1.1	1.5	-1.2	-1.3	-0.2	-1.3	-2.2	-0.9	-1.3	-0.8	-1.2	-1.6	-1.2	-1.6	-1.5	-1.7	-1.6
Systolic blood pressure, automated reading	1.2	3.6	6.1	2.3	2.0	-2.3	1.1	2.1	-0.9	2.2	1.4	2.3	1.1	-1.0	0.4	2.5	1.5	2.1	2.5	2.3	2.3
Eye problems/disorders: Diabetes related eye disease	1.3	1.4	4.5	1.8	1.3	-0.9	-0.2	1.0	-2.1	0.5	0.4	1.4	-0.6	-1.0	-1.2	1.1	0.1	1.7	1.5	1.2	0.9
Angina	0.4	0.6	3.5	-0.1	0.6	-0.3	0.3	0.8	1.4	0.0	1.9	0.2	0.8	0.0	1.0	0.6	1.0	-0.3	-0.1	0.1	0.0
Medication for hormone replacement therapy	0.6	0.7	1.6	1.2	1.0	-0.9	0.8	1.3	0.2	0.3	-0.1	1.1	0.7	0.6	0.7	0.7	1.0	0.7	0.8	0.9	1.0
Vitamin and mineral supplements	0.1	0.1	0.8	-0.3	-0.4	0.0	0.2	-0.6	0.9	-0.4	-0.2	-0.4	0.4	0.3	0.5	-0.2	-0.1	-0.0	-0.3	-0.2	-0.1
Supplements: Zinc	2.9	3.2	6.5	-1.6	-1.9	1.9	-2.0	-1.4	-1.1	-1.2	-1.4	-1.9	-1.9	-1.8	-2.1	-1.6	-1.9	-2.5	-1.6	-1.9	-1.8
Medication: Co-codamol	1.4	1.7	4.6	1.5	1.3	-1.3	0.6	1.5	-1.4	0.4	2.0	1.5	0.1	0.7	-0.4	1.2	-0.1	2.1	1.6	1.4	1.4
Medication: Metformin	0.5	0.7	3.3	0.5	-0.6	0.2	-1.0	-0.4	-1.8	0.2	0.7	-0.4	-1.2	-1.2	-1.6	-0.0	-0.9	0.0	0.3	0.0	-0.1
Diabetes (father)	0.6	0.7	3.5	0.5	-0.1	0.0	-1.1	-0.7	-1.9	-0.8	-0.1	-0.1	-1.0	-1.3	-1.5	-0.0	-0.8	0.3	0.5	0.2	0.1
Diabetes (mother)	0.4	0.5	3.2	0.6	0.6	-0.8	0.6	-0.4	-0.1	0.5	1.8	0.6	0.3	1.3	0.1	0.7	-0.2	-0.0	0.8	0.6	0.7
Severe depression (siblings)	0.2	0.2	1.1	-0.2	-0.7	0.2	-0.4	-0.8	-0.2	-0.1	1.1	-0.7	-0.5	-0.4	-0.3	-0.0	-0.4	-0.6	-0.0	-0.0	-0.1
Pack years adult smoking proportion	0.3	0.4	1.1	-0.1	-0.1	0.6	-0.3	-0.6	-1.0	-0.1	-0.3	-0.2	-1.1	0.7	-0.9	-0.6	-0.8	-0.8	-0.4	-0.6	-0.7
Impedance of leg (right)	7.7	37.3	50.7	-6.3	-6.5	7.0	-6.1	-6.3	0.3	-6.2	-6.5	-7.0	-5.1	-5.6	-3.4	-6.8	-5.1	-6.6	-7.1	-6.9	-7.0
Leg fat-free mass (left)	0.4	2.2	10.1	-0.6	1.0	-0.3	2.1	1.5	3.2	0.8	2.4	0.7	2.0	1.8	2.5	0.3	1.2	-0.4	-0.6	-0.1	0.0
Trunk fat percentage	0.2	0.6	2.4	0.8	0.7	-0.6	0.5	1.2	-0.6	1.3	1.6	1.0	0.2	-0.8	-0.1	0.8	-0.1	0.1	0.8	0.7	0.7
Hand grip strength (right)	1.5	4.1	8.7	-2.7	-1.7	2.5	-1.1	-1.4	1.6	-2.6	-2.1	-2.1	-1.0	-0.5	-0.0	-2.5	-1.0	-2.0	-3.0	-2.6	-2.7
Townsend deprivation index at recruitment	2.7	3.8	6.2	2.4	1.9	-2.3	1.3	2.2	-0.8	2.1	2.2	2.0	1.2	0.9	0.7	2.4	1.9	2.3	2.5	2.3	2.2
Current tobacco smoking	0.4	0.6	1.4	0.9	1.2	-0.7	0.5	0.9	0.1	0.8	1.2	1.1	0.4	-0.1	0.5	0.9	0.9	0.6	0.7	0.7	0.7
Average weekly fortified wine intake	0.3	0.4	2.0	0.0	0.4	-0.0	0.1	-0.1	-1.4	-0.4	-0.1	0.7	-0.7	0.7	-1.1	-0.3	-0.7	0.7	0.4	0.1	0.1
Maternal smoking around birth	1.1	1.6	4.1	0.5	1.4	-0.9	1.4	0.9	1.8	1.1	1.8	0.8	1.5	2.0	1.9	1.1	1.0	-0.1	0.4	0.7	0.7
Fed-up feelings	0.1	0.2	1.3	-0.1	0.3	-0.1	-0.2	0.1	-0.6	-0.9	-0.7	0.1	-0.5	-0.2	-0.5	0.1	-0.5	1.1	0.3	0.1	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.3	6.6	1.3	1.4	-1.8	1.6	0.9	-0.2	1.7	2.6	1.5	1.1	1.0	0.8	1.8	1.0	1.5	1.8	1.8	1.8
Relative age voice broke	0.6	1.0	4.8	1.0	0.4	-0.8	-0.5	-0.1	-1.1	0.9	-1.1	0.6	-0.0	-2.2	-0.4	1.0	0.2	1.5	1.1	1.0	1.0
Taking other prescription medications	3.9	6.0	9.4	2.8	2.9	-2.7	2.3	2.5	0.2	3.1	2.9	2.8	2.1	1.3	1.5	2.9	2.1	2.1	2.7	2.8	2.7
Age when periods started (menarche)	0.1	0.3	4.1	0.2	0.2	-0.0	-0.2	0.2	0.1	0.3	-0.3	0.1	-0.1	-2.0	0.4	0.1	0.4	0.1	-0.0	0.1	0.1
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	1.1	0.3	0.4	-0.7	1.0	0.4	0.6	0.6	0.3	0.6	0.9	0.9	0.7	0.5	0.9	0.3	0.6	0.6	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	2.2	-0.6	-1.1	0.4	-0.5	-0.5	-0.1	-0.7	0.7	-1.1	-0.7	-1.5	-0.4	-0.4	0.3	-0.9	-0.4	-0.6	-0.5
Tinnitus: Yes, but not now, but have in the past	1.1	1.1	1.7	1.1	1.1	-1.2	1.0	1.1	-0.0	1.3	1.2	1.2	0.9	0.5	0.5	1.3	1.2	0.8	1.3	1.2	1.3
Qualifications: CSEs or equivalent	0.6	0.8	6.6	0.0	-0.3	0.5	-0.9	-0.1	-1.4	-0.4	-2.6	-0.3	-1.2	-1.1	-1.3	-0.5	-0.4	-0.4	-0.1	-0.3	-0.3
Serious illness, injury or assault to yourself	1.3	1.6	2.5	1.0	1.3	-1.5	1.3	1.6	0.3	1.2	1.4	1.1	1.1	1.3	0.9	1.4	1.5	0.7	1.4	1.5	1.5
High blood pressure	4.2	11.8	26.1	2.6	3.9	-3.6	3.9	3.5	2.2	3.6	5.1	3.7	3.8	2.5	3.6	3.6	3.4	1.5	2.9	3.3	3.4
Hayfever, allergic rhinitis or eczema	1.2	2.6	4.5	1.9	1.7	-1.8	0.8	1.2	-0.6	2.1	1.7	2.0	1.0	-1.1	0.6	2.1	0.7	1.9	2.0	2.1	2.1
Multivitamins +/- minerals	1.1	1.4	4.0	-0.9	-1.1	1.1	-1.4	-1.3	-2.0	-0.3	-0.5	-0.9	-1.8	-0.7	-2.0	-1.0	-1.3	-0.9	-0.6	-0.9	-0.9
Stomach or abdominal pain in last month	0.3	0.4	1.1	0.8	-0.0	-0.5	-0.3	-0.1	-0.8	0.5	0.9	0.3	-0.3	-1.0	-0.4	0.5	0.3	0.7	0.7	0.7	0.7
Supplements: Glucosamine	0.1	0.1	0.4	-0.5	0.3	-0.0	0.0	0.2	0.2	0.2	0.1	0.4	0.4	-0.6	0.2	0.0	0.3	0.5	-0.1	-0.0	0.1
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	1.3	0.9	-0.1	-0.2	-0.1	-0.1	-1.0	-0.8	-0.1	0.0	-0.4	0.6	-0.7	0.0	-1.1	0.3	0.5	0.2	0.3
Medication: Atenolol	0.6	0.8	4.2	-0.7	0.4	-0.1	1.0	0.2	2.0	0.5	1.0	0.1	1.2	0.9	1.5	0.0	1.1	-0.8	-0.5	-0.3	-0.1
Medication: Levothyroxine sodium	2.2	3.8	6.2	1.9	2.5	-2.0	2.2	2.2	1.1	1.9	1.2	2.2	2.0	1.9	2.0	2.0	1.8	1.6	1.7	2.0	2.0
Sitting height	3.7	26.2	57.3	-7.2	-4.6	6.2	-2.3	-3.3	4.8	-5.6	-2.4	-5.5	-2.1	-0.7	0.4	-6.4	-3.3	-6.8	-7.6	-6.9	-6.8
Chronic bronchitis/emphysema (father)	0.3	0.4	1.8	0.0	0.6	-0.5	0.9	1.4	-0.0	1.2	-0.1	0.7	0.4	0.8	0.2	0.3	0.2	0.4	0.5	0.4	0.6
High blood pressure (mother)	0.8	1.2	2.3	1.2	1.3	-1.0	0.9	1.5	0.1	1.4	1.4	1.4	0.7	0.8	0.7	1.1	0.9	0.3	1.0	1.1	1.1
Body mass index (BMI)	4.1	17.5	25.8	4.7	4.3	-4.8	4.0	4.3	-1.0	5.1	5.0	4.8	3.2	2.4	1.7	4.7	3.0	4.1	5.1	4.9	4.9
Impedance of leg (left)	8.1	39.5	54.3	-6.6	-6.5	7.3	-6.3	-6.4	0.4	-6.7	-6.9	-7.0	-5.3	-5.2	-3.4	-7.0	-5.2	-7.0	-7.4	-7.2	-7.3
Leg predicted mass (left)	0.4	2.3	10.4	-0.6	0.9	-0.3	2.0	1.5	3.2	0.8	2.4	0.6	2.1	1.8	2.6	0.3	1.2	-0.4	-0.6	-0.1	0.0
Trunk fat mass	0.1	0.6	2.9	0.0	0.7	-0.2	1.1	1.4	0.9	1.0	1.7	0.8	0.7	-0.0	0.8	0.3	0.1	-0.4	-0.0	0.1	0.1
Waist circumference	0.5	2.0	6.0	1.0	1.5	-1.3	1.5	2.3	0.7	1.8	2.5	1.6	1.3	-0.2	1.2	1.4	1.2	0.6	1.1	1.2	1.1
Number of incorrect matches in round	0.7	1.2	3.0	-0.3	-1.5	0.7	-1.4	-1.0	-1.6	-0.6	-1.1	-1.5	-1.4	0.4	-1.6	-0.8	-1.7	-0.4	-0.3	-0.7	-0.7
Past tobacco smoking	0.0	0.1	0.6	0.3	-0.1	-0.1	0.2	-0.2	0.2	-0.5	0.8	-0.0	0.2	0.5	0.4	0.1	0.4	-0.0	0.1	0.1	0.2
Alcohol usually taken with meals	2.6	4.3	9.2	-2.4	-2.1	2.5	-1.1	-1.1	0.6	-3.0	-1.2	-2.3	-1.7	-0.4	-1.0	-2.9	-2.0	-2.5	-2.7	-2.4	-2.6
Nervous feelings	0.1	0.3	2.1	-0.0	-0.2	0.1	0.4	-0.5	-0.3	-0.2	-0.7	-0.3	-0.4	0.9	-0.3	-0.3	-1.4	0.4	-0.1	-0.0	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	1.0	-1.0	-0.6	0.6	-0.9	-1.0	0.7	-0.8	-0.1	-0.8	-0.0	-0.6	0.3	-0.2	-0.7	-0.6	-0.8	-0.6	-0.6
Hearing difficulty/problems with background noise	0.8	1.2	3.8	-2.0	-1.4	1.1	-0.4	-0.9	0.6	-0.5	-0.3	-1.4	-0.7	0.2	-0.2	-1.1	-0.7	-1.8	-1.3	-1.4	-1.3
Hair/balding pattern: Pattern 2	0.8	1.0	2.8	-0.3	-1.0	0.7	-1.3	-0.6	-1.6	-0.3	-1.6	-0.6	-1.3	-1.4	-1.7	-0.8	-1.2	-0.6	-0.2	-0.5	-0.5
Had menopause	0.7	0.9	5.5	0.2	-0.6	0.1	-0.0	-0.2	-2.4	-0.5	-0.0	-0.3	-1.1	1.1	-1.8	-0.7	-1.5	1.0	0.5	0.1	0.0
Had other major operations	0.3	0.3	1.9	0.2	0.9	-0.2	1.4	1.1	-0.1	-0.2	-0.4	0.8	0.0	0.7	0.2	-0.2	-0.1	0.5	0.2	0.5	0.4
Forced vital capacity (FVC)	1.7	6.6	14.0	-3.7	-2.0	2.7	-0.2	-1.5	3.6	-2.9	-2.3	-2.8	-0.2	1.3	1.3	-2.9	-0.5	-3.3	-3.7	-3.1	-3.2
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.6	2.6	-0.5	-0.9	-0.0	0.0	-1.1	1.0	0.3	0.5	-0.9	0.3	-1.6	0.6	0.0	1.3	-0.8	-0.3	-0.3	-0.2
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	0.8	-0.5	0.5	-0.3	0.8	0.2	0.8	0.2	-0.5	0.3	0.8	0.9	0.8	0.2	0.9	0.4	0.0	0.0	0.2
Qualifications: None of the above	5.9	12.6	20.6	4.5	3.2	-4.2	3.3	2.6	-0.8	4.4	3.9	3.7	2.9	2.0	1.7	4.0	3.2	4.1	4.4	4.2	4.2
Financial difficulties in last 2 years	0.3	0.4	1.1	-0.7	-0.4	0.8	-0.7	0.3	0.2	-0.6	-0.7	-0.5	-0.5	-0.2	-0.4	-0.7	-0.6	-1.0	-0.8	-0.9	-0.8
Mouth/teeth dental problems	8.5	13.1	21.5	-4.4	-3.2	4.5	-3.0	-2.8	0.6	-4.5	-2.3	-3.5	-2.9	-1.3	-1.9	-4.4	-3.8	-4.4	-4.6	-4.6	-4.5
Heart attack	0.9	1.1	5.4	-0.8	-0.7	0.4	-0.7	-0.8	2.3	0.7	1.1	-1.0	1.1	-1.3	1.6	0.2	1.0	-1.3	-1.0	-0.6	-0.5
Allergy	1.2	2.8	5.1	-2.0	-1.8	1.8	-0.3	-1.3	1.3	-2.0	-1.9	-2.2	-0.7	0.8	-0.1	-2.1	-0.4	-2.3	-2.1	-2.1	-2.1
Pain all over the body in last month	0.5	0.5	1.3	0.2	0.5	-0.8	0.6	-0.1	0.7	0.9	-0.5	0.5	1.1	-0.3	1.0	1.0	1.1	0.4	0.6	0.6	0.6
Diabetes (self-reported)	0.6	1.0	6.5	0.8	-0.4	-0.1	-1.0	-0.0	-2.6	0.4	1.3	-0.0	-1.2	-0.6	-1.9	0.2	-1.1	0.6	0.7	0.3	0.2
Hayfever/allergic rhinitis (self-reported)	1.5	2.0	3.5	1.6	1.3	-1.6	0.4	0.9	-1.0	1.8	1.8	1.7	0.7	-1.0	0.1	1.8	1.0	1.6	1.9	1.7	1.8
Medication: Ramipril	0.6	0.7	1.6	1.2	0.6	-1.2	1.0	0.7	-0.5	0.6	1.0	0.6	0.5	-0.9	0.0	0.8	0.2	0.8	1.3	1.1	1.1
Medication: Simvastatin	0.2	0.4	1.6	-0.0	-0.1	-0.4	-0.1	-0.0	0.5	0.7	1.3	-0.2	0.3	-1.3	0.6	0.7	0.5	-0.9	0.2	0.2	0.2
Fluid intelligence score	0.5	1.0	2.4	-1.0	-1.0	0.8	-0.2	-1.3	1.4	-1.5	-0.5	-1.2	0.2	-1.0	0.5	-0.8	-0.4	-1.1	-1.2	-1.0	-1.0
Illnesses of siblings	0.5	0.7	1.6	1.2	0.9	-0.9	0.7	-0.2	-1.3	0.8	-0.3	0.8	0.2	0.7	-0.3	0.8	0.4	0.6	1.2	1.1	1.0
Neuroticism score	0.7	1.4	3.1	-1.8	-1.1	1.3	-0.8	-1.1	0.2	-1.3	-0.7	-1.4	-1.1	0.1	-0.5	-1.4	-1.6	-0.9	-1.4	-1.4	-1.4
Weight	0.3	1.5	5.1	-0.4	0.8	-0.2	1.9	1.7	2.3	0.8	2.2	0.7	1.5	1.2	1.8	0.1	0.7	-0.6	-0.4	-0.0	-0.0
Impedance of arm (right)	3.0	14.2	19.5	-3.2	-3.7	4.4	-4.4	-3.2	-1.1	-3.8	-3.9	-3.8	-3.9	-4.2	-3.0	-4.2	-3.5	-3.7	-4.1	-4.1	-4.3
Arm fat percentage (right)	2.0	7.7	14.0	3.5	3.0	-3.0	2.3	3.2	-1.4	3.7	3.4	3.5	1.6	0.6	0.5	3.0	1.5	2.5	3.4	3.2	3.2
Trunk fat-free mass	1.1	6.1	33.4	-3.2	-0.6	1.9	1.6	0.4	5.8	-1.2	0.9	-1.3	1.8	1.9	3.4	-2.1	0.7	-2.8	-3.5	-2.6	-2.5
Hip circumference	0.5	2.3	9.4	0.5	1.8	-0.8	2.2	2.7	1.6	1.4	3.1	1.7	1.5	1.1	1.7	0.7	0.9	0.6	0.4	0.7	0.7
Time employed in main current job	3.0	3.4	7.1	1.4	2.1	-1.9	2.7	2.5	0.9	1.4	0.6	2.2	2.0	2.0	1.7	1.6	1.4	2.5	1.6	1.7	1.8
Alcohol intake versus 10 years previously	0.4	0.7	1.8	1.4	0.5	-1.0	0.5	0.1	-0.3	1.3	1.0	0.4	0.4	-0.3	0.2	1.2	0.9	0.2	1.1	1.1	0.9
Father’s age at death	1.5	2.0	6.0	1.1	2.0	-1.3	1.1	1.8	-1.7	1.0	0.6	2.2	0.1	1.0	-0.6	1.1	0.8	2.5	1.8	1.4	1.4
Worrier / anxious feelings	0.3	0.6	1.4	-0.7	-0.8	0.6	-0.3	-0.9	0.9	-0.8	0.9	-1.2	-0.0	-0.0	0.4	-0.5	-0.6	-1.2	-0.9	-0.7	-0.8
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.7	-0.5	0.4	-0.2	0.3	-0.3	0.8	0.5	0.8	0.1	0.3	0.0	0.6	0.4	0.5	-0.2	-0.1	0.1	0.1
Falls in the last year	0.1	0.2	0.8	0.1	0.2	-0.1	-0.3	0.2	-0.9	0.1	-0.6	0.3	-0.6	-0.5	-0.7	0.2	-0.4	0.4	0.3	0.1	0.1
Hair/balding pattern: Pattern 3	0.9	1.3	8.6	-0.8	-0.6	1.1	-0.4	-1.1	0.1	-2.9	-0.5	-0.7	-0.5	0.8	-0.4	-1.1	-2.1	-0.2	-1.1	-1.2	-1.2
Number of live births	0.1	0.1	0.6	-0.3	-0.2	0.0	-0.4	0.2	-0.8	-0.3	-0.5	0.0	-0.5	-0.6	-0.5	-0.1	0.1	0.1	0.2	0.0	0.1
Forced expiratory volume in 1-second (FEV1)	1.1	3.7	12.0	-2.9	-1.2	1.7	0.3	-0.7	3.5	-1.9	-1.9	-1.9	0.5	1.1	1.7	-1.8	0.3	-2.3	-2.7	-2.2	-2.2
Pulse rate	0.4	0.6	1.2	-0.5	-1.0	0.7	-0.9	-0.4	-0.8	-1.1	-0.9	-1.0	-1.1	0.0	-1.1	-0.8	-0.9	-0.3	-0.5	-0.7	-0.7
Happiness	0.2	0.2	1.9	-0.6	0.2	-0.1	0.5	-0.0	0.5	-0.7	-0.1	-0.2	0.2	1.4	0.3	-0.2	0.0	0.5	0.0	-0.1	-0.1
Noisy workplace	1.6	2.0	4.5	2.1	1.0	-1.6	0.9	1.7	-0.1	2.1	1.4	1.2	1.1	0.4	0.8	1.6	1.6	1.3	1.7	1.6	1.7
Qualifications: A levels/AS levels or equivalent	5.6	12.3	23.8	-4.1	-3.5	4.3	-2.8	-2.9	2.1	-4.5	-2.8	-3.9	-2.0	-1.7	-0.7	-4.3	-2.7	-3.8	-4.9	-4.4	-4.4
Serious illness, injury or assault of a close relative in last 2 years	1.6	1.8	4.2	2.1	1.5	-1.1	0.8	1.3	-1.9	1.2	1.6	1.9	-0.1	0.9	-0.8	0.9	-0.2	1.6	1.7	1.4	1.4
Mouth/teeth dental problems: Dentures	7.0	11.8	25.1	3.7	3.4	-4.0	3.2	3.1	0.8	5.0	2.8	3.6	3.4	1.0	2.8	4.0	3.9	3.1	3.7	3.8	3.8
Asthma	0.2	0.3	1.3	0.7	0.4	-0.3	-0.8	0.1	-1.1	0.1	0.7	0.7	-0.3	-0.5	-0.6	0.6	-0.5	0.4	0.6	0.4	0.4
Medication: Ibuprofen (e.g. Nurofen)	1.5	1.9	4.7	-1.2	-1.2	1.6	-1.2	-1.3	-0.6	-1.1	0.1	-1.5	-1.6	0.2	-1.3	-1.7	-2.0	-2.2	-1.5	-1.4	-1.5
Medication: Cholesterol lowering	0.7	1.1	8.0	-1.2	-1.0	0.8	-1.4	-0.6	0.4	-0.1	0.3	-1.1	-0.5	-2.8	-0.1	-0.4	-0.1	-1.6	-0.9	-0.9	-0.9
Depression (self-reported)	1.3	1.5	4.9	-1.2	-1.5	1.1	-1.2	-2.2	-1.1	-1.0	-0.7	-1.2	-1.4	-0.9	-1.5	-1.0	-1.3	-1.1	-0.8	-1.2	-1.1
Medication: Lansoprazole	0.5	0.6	3.1	-0.4	0.2	0.1	0.1	0.7	1.8	0.3	0.4	-0.1	0.9	-1.3	1.4	0.1	1.0	-0.4	-0.6	-0.2	-0.1
Prospective memory result	0.4	0.5	1.8	0.1	-0.3	0.4	-0.1	-0.8	-1.3	-0.4	-0.6	-0.2	-1.1	0.5	-1.2	-0.6	-1.3	0.2	-0.1	-0.2	-0.3
Lung cancer (father)	0.8	0.9	3.0	0.9	0.7	-1.1	1.5	-0.1	0.2	1.1	0.9	0.9	1.0	1.7	0.7	0.7	0.5	0.3	1.0	1.1	1.0
Illnesses of mother	1.9	2.4	7.4	-1.5	-1.1	1.7	-1.7	-1.4	-0.9	-1.6	-2.7	-1.1	-1.6	-1.7	-1.6	-1.5	-1.2	-0.5	-1.5	-1.5	-1.7
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.1	11.8	-2.4	-1.0	1.6	0.3	-0.4	3.4	-1.5	-1.9	-1.6	0.6	0.2	1.6	-1.7	0.6	-1.9	-2.6	-2.1	-2.1
Pulse wave Arterial Stiffness index	5.3	6.2	10.1	-2.5	-2.6	2.7	-2.3	-2.9	-0.7	-2.5	-2.4	-2.7	-2.5	-1.0	-2.0	-2.8	-3.2	-2.9	-2.6	-2.5	-2.6
Impedance of arm (left)	3.0	13.7	20.6	-3.2	-3.8	4.2	-4.5	-3.4	-1.4	-4.0	-3.7	-3.9	-3.9	-4.2	-3.1	-3.9	-3.6	-3.2	-3.7	-3.9	-4.0
Arm fat mass (right)	1.4	5.8	12.5	2.5	2.5	-2.5	2.7	2.8	0.2	3.2	3.5	2.8	2.1	1.2	1.5	2.5	1.6	1.7	2.4	2.5	2.5
Trunk predicted mass	1.1	6.2	34.2	-3.2	-0.6	1.9	1.6	0.3	5.8	-1.3	0.9	-1.4	1.8	1.9	3.4	-2.1	0.7	-2.8	-3.5	-2.6	-2.5
Standing height	6.1	60.7	132.2	-10.7	-7.0	9.5	-4.0	-5.2	7.3	-8.6	-5.2	-8.5	-3.1	-2.2	0.6	-9.5	-4.6	-9.8	-11.5	-10.3	-10.3
Length of working week for main job	1.2	1.3	3.5	1.0	1.1	-1.1	1.3	0.8	0.9	1.2	1.9	1.1	1.4	1.0	1.4	1.0	1.0	1.0	0.9	1.1	1.2
Exposure to tobacco smoke at home	0.8	0.9	1.9	1.0	1.1	-1.1	0.8	0.4	-0.8	1.0	0.6	1.3	0.4	0.6	-0.1	1.1	0.8	1.1	1.4	1.2	1.1
Breastfed as a baby	0.7	0.9	2.8	-1.3	-0.8	1.1	-0.1	-0.2	1.5	-0.5	-0.6	-0.9	0.0	0.0	0.6	-1.0	0.0	-1.7	-1.5	-1.3	-1.2
Tense / ‘highly strung’	0.3	0.5	1.1	-1.0	-0.7	0.7	0.1	-0.6	0.8	-0.4	-0.6	-0.9	-0.4	0.4	0.2	-0.8	-1.1	-1.0	-1.0	-0.7	-0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.7	-0.4	-0.5	0.2	0.1	-0.3	0.1	-0.6	0.5	-0.6	-0.4	0.6	-0.1	-0.4	-0.8	-0.5	-0.2	-0.2	-0.2
Hair/balding pattern: Pattern 4	0.1	0.4	2.7	-0.2	-0.4	0.1	0.2	0.3	0.3	-1.2	0.7	-0.2	0.0	-0.2	0.2	-0.1	-1.6	1.1	-0.1	0.2	0.1
Birth weight of first child	0.2	0.4	1.5	0.3	0.2	-0.6	1.2	-0.6	0.4	0.7	0.6	0.3	0.9	1.1	0.6	0.3	0.4	0.7	0.5	0.5	0.6
Peak expiratory flow (PEF)	0.7	1.6	10.2	-1.0	-0.0	-0.0	1.3	0.9	3.2	-0.3	0.3	-0.5	1.8	1.1	2.5	-0.0	1.7	-0.4	-0.9	-0.3	-0.3
Pulse wave reflection index	6.3	7.8	12.7	-3.3	-2.9	3.2	-1.8	-3.4	0.4	-2.8	-3.2	-3.0	-2.2	-0.4	-1.3	-3.4	-3.0	-3.6	-3.3	-3.1	-3.1
Ever highly irritable/argumentative for 2 days	0.2	0.3	2.0	0.2	0.3	-0.1	-0.1	-0.7	0.5	0.6	-1.0	0.3	0.5	-1.4	0.4	0.3	0.6	0.2	0.0	0.1	0.1
Loud music exposure frequency	0.1	0.1	0.8	-0.5	0.4	0.4	-0.2	0.4	0.4	-0.0	0.9	0.3	-0.1	-0.0	0.0	-0.3	0.1	-0.5	-0.5	-0.4	-0.2
Qualifications: O levels/GCSEs or equivalent	4.2	6.7	14.7	-3.3	-2.0	3.1	-2.0	-1.2	2.8	-3.1	-2.2	-2.6	-0.9	-1.9	0.4	-2.8	-0.9	-3.5	-3.8	-3.3	-3.3
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.8	0.8	-0.2	-0.7	0.0	-0.7	-1.4	0.6	0.5	-0.0	-0.3	0.2	-0.6	0.7	0.1	1.3	1.1	0.9	0.9
Blood clot in the leg (DVT)	1.1	1.4	3.0	0.9	1.4	-1.2	1.2	1.0	1.3	0.9	1.0	1.1	1.6	-0.2	1.7	1.3	1.7	1.1	0.9	1.1	1.1
Medication: Paracetamol	0.3	0.5	2.0	-0.7	-0.0	0.4	0.5	-0.3	1.0	-0.3	-1.4	-0.4	0.2	1.1	0.7	-0.5	-0.5	-0.7	-0.8	-0.4	-0.5
Headache pain in last month	0.1	0.1	0.7	-0.3	-0.2	0.2	0.3	-0.7	-0.2	-0.0	-0.4	-0.3	-0.6	0.1	-0.4	-0.5	-0.1	-0.8	-0.2	-0.1	-0.1
Medication for cholesterol, blood pressure or diabetes	0.8	1.4	3.9	-0.4	-0.9	1.2	-0.6	-2.0	-1.3	-1.0	-1.9	-0.7	-1.3	0.8	-1.5	-1.4	-1.6	0.1	-0.8	-0.9	-0.9
Glaucoma (self-reported)	0.2	0.2	0.8	0.1	0.1	-0.3	0.1	-0.0	0.9	0.5	-0.6	-0.2	0.6	-0.4	0.7	0.6	0.8	-0.3	0.0	-0.0	0.0
Gout (self-reported)	1.3	1.7	4.3	1.2	1.7	-1.3	0.5	0.8	1.1	1.5	2.1	1.6	1.4	0.3	1.5	1.6	1.6	0.7	0.9	1.2	1.1
Hypothyroidism/myxoedema (self-reported)	4.0	7.9	12.0	3.4	3.5	-3.0	2.9	2.8	0.4	3.5	2.1	3.4	2.4	2.2	1.9	3.0	2.5	2.6	3.0	3.2	3.1
Medication: Amlodipine	4.2	5.9	8.8	2.1	2.7	-2.9	2.6	2.5	0.6	2.8	2.3	2.8	2.5	2.2	1.8	3.0	2.2	1.7	2.7	2.7	2.7
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.8	0.8	0.4	-0.3	-0.1	0.2	-0.9	0.8	-0.2	0.6	-0.2	0.6	-0.4	0.6	-0.4	0.3	0.6	0.5	0.6
Birth weight	0.1	0.3	2.7	-0.1	0.1	-0.2	1.0	0.4	0.6	-0.6	-0.6	-0.1	0.3	1.6	0.5	-0.2	0.2	0.5	-0.1	0.1	0.0
Chronic bronchitis/emphysema (mother)	1.4	1.6	3.8	0.9	1.6	-1.4	0.9	0.9	0.3	1.9	0.9	1.6	1.0	-0.4	1.1	1.7	1.9	0.1	1.4	1.4	1.4
High blood pressure (siblings)	0.3	0.4	2.1	-0.8	-0.3	0.7	-0.1	0.1	1.5	0.0	0.8	-0.3	0.2	-0.5	0.6	-0.5	0.4	-0.8	-1.0	-0.8	-0.7
Forced vital capacity (FVC), Best measure	1.3	4.8	11.8	-3.1	-1.4	2.4	0.0	-1.0	3.4	-2.4	-2.2	-2.1	-0.0	0.8	1.3	-2.6	-0.3	-2.4	-3.4	-2.8	-2.8
Body fat percentage	0.4	1.4	3.6	1.4	1.2	-1.1	0.8	1.5	-1.0	1.9	1.8	1.5	0.4	-0.5	-0.1	1.2	0.2	0.7	1.4	1.3	1.2
Leg fat percentage (right)	0.5	1.8	4.8	1.6	1.3	-1.4	1.0	1.6	-1.2	2.2	1.7	1.7	0.5	-0.6	-0.2	1.4	0.3	1.2	1.7	1.6	1.5
Arm fat-free mass (right)	0.6	3.3	16.4	-2.6	-0.6	1.4	1.2	-0.1	4.0	-1.1	0.9	-1.2	1.3	1.7	2.3	-1.4	0.1	-2.0	-2.5	-1.9	-1.8
Exposure to tobacco smoke outside home	0.5	0.7	1.5	0.3	1.2	-0.8	1.0	1.2	0.3	0.9	0.9	1.2	0.7	0.4	0.7	0.8	0.7	0.3	0.7	0.9	0.8
Comparative body size at age 10	5.8	16.0	22.7	4.3	4.4	-4.4	4.8	3.8	1.0	4.3	3.2	4.7	4.0	3.7	3.1	4.2	3.8	3.5	4.2	4.5	4.4
Number of full brothers	0.3	0.4	2.0	-0.1	0.5	-0.4	0.1	-0.6	0.8	0.8	-0.2	0.2	0.6	-0.7	1.0	0.7	1.4	-0.7	0.2	0.2	0.3
Worry too long after embarrassment	9.2	15.5	21.2	-3.9	-4.2	4.6	-4.4	-3.4	-1.8	-3.6	-3.2	-4.4	-4.5	-1.7	-3.7	-4.6	-4.5	-3.7	-4.1	-4.4	-4.4
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	2.5	1.2	1.2	-1.1	1.6	1.1	0.7	1.0	0.9	1.2	1.3	1.3	1.3	0.9	1.1	0.6	1.0	1.1	1.2
Wheeze or whistling in the chest in last year	1.5	2.7	5.9	2.3	1.1	-2.1	0.8	0.3	-0.9	2.3	1.6	1.5	1.0	-0.2	0.3	2.4	1.7	1.6	2.4	2.0	2.1
Number of children fathered	0.8	0.9	1.9	0.5	0.9	-0.9	0.7	0.5	0.8	1.1	1.4	0.7	1.3	0.3	1.2	1.0	1.4	0.6	0.7	0.9	1.0
Reason for reducing amount of alcohol drunk: Health precaution	2.3	2.7	4.3	-1.6	-2.1	1.9	-2.0	-1.2	-0.8	-1.5	-0.0	-1.8	-1.7	-0.1	-1.8	-2.0	-2.1	-1.3	-1.7	-2.0	-1.9
Age at first live birth	2.6	4.7	7.8	-2.2	-2.1	2.3	-2.1	-2.4	-0.7	-2.1	-2.8	-2.1	-2.2	-2.3	-1.9	-2.4	-2.1	-1.9	-2.1	-2.2	-2.3
Pulse wave peak to peak time	3.2	3.7	7.4	1.7	2.0	-2.0	1.7	2.4	1.2	1.8	2.1	1.9	2.2	0.7	2.0	2.1	2.7	2.1	1.7	1.7	1.8
Health satisfaction	0.5	0.6	1.8	-1.1	-0.7	0.6	-0.8	-0.6	-1.0	-0.8	-0.7	-0.6	-1.1	-1.2	-1.3	-0.7	-0.3	-0.4	-0.4	-0.7	-0.7
Shortness of breath walking on level ground	0.1	0.1	0.6	0.3	0.5	-0.3	0.6	0.8	0.1	0.6	0.3	0.4	0.0	0.1	-0.2	0.1	0.2	0.1	0.2	0.2	0.1
Qualifications: College or University degree	1.7	5.2	11.3	-2.5	-1.9	2.8	-1.4	-2.0	1.0	-3.4	-1.1	-2.2	-1.4	-0.9	-0.7	-2.9	-2.4	-2.9	-3.1	-2.7	-2.9
Eye problems/disorders: None of the above	0.8	0.9	1.7	-1.0	-0.8	1.0	-0.4	-0.1	0.0	-1.2	-0.4	-0.9	-1.0	0.9	-0.6	-1.2	-1.3	-1.3	-1.0	-1.1	-1.1
Mouth/teeth dental problems: Loose teeth	2.4	2.8	5.3	-2.3	-2.0	1.8	-1.6	-2.3	0.4	-1.2	-0.4	-2.2	-1.2	-1.7	-0.7	-1.7	-1.2	-2.1	-1.9	-1.8	-1.9
Emphysema/chronic bronchitis	1.0	1.1	4.0	-0.1	-1.4	0.6	-1.1	-0.4	-2.0	-0.6	0.1	-1.0	-1.6	-0.2	-2.0	-0.8	-1.7	0.1	-0.0	-0.5	-0.4
Medication for pain relief, constipation, heartburn	0.1	0.2	1.5	0.2	-0.2	-0.1	-0.5	-0.2	-0.8	-0.3	-0.6	0.2	-0.2	-0.7	-0.6	0.1	0.2	1.2	0.4	0.2	0.3
Neck or shoulder pain in last month	1.2	1.6	3.0	1.6	0.8	-1.7	1.7	0.9	0.0	1.1	1.1	0.8	1.3	1.3	0.8	1.5	1.0	1.0	1.7	1.7	1.7
Medication: Blood pressure	4.8	8.5	15.8	2.1	3.1	-3.1	3.2	3.5	2.4	2.9	4.0	2.8	3.4	2.4	3.3	3.1	3.1	1.2	2.4	2.7	2.8
Angina (self-reported)	0.3	0.4	3.0	-0.1	0.5	-0.2	0.1	0.7	1.2	0.1	1.7	0.1	0.6	-0.1	0.8	0.5	0.9	-0.5	-0.1	0.0	-0.0
Migraine (self-reported)	0.5	0.7	2.6	-0.8	-0.7	0.7	-0.2	-0.8	1.0	0.2	-1.6	-0.8	0.0	-0.7	0.5	-0.7	-0.1	-1.5	-1.0	-0.7	-0.6
Medication: Ibuprofen	0.7	0.9	2.8	-0.5	-0.4	1.0	-0.9	-0.6	-0.8	-0.7	0.8	-0.7	-1.3	0.4	-1.1	-1.0	-1.7	-1.2	-0.8	-0.8	-0.9
Medication: Allopurinol	0.3	0.4	1.1	0.5	0.7	-0.7	0.3	0.3	-0.2	0.7	1.1	0.8	0.3	0.5	0.1	0.7	0.4	0.3	0.7	0.7	0.7
Medication: Omeprazole	2.9	3.4	6.0	-2.5	-2.0	2.1	-1.9	-1.7	0.0	-2.0	-0.5	-2.0	-1.6	-1.7	-1.1	-1.8	-1.6	-2.0	-2.2	-2.4	-2.2
Medication: Seretide 50 evohaler	0.9	1.0	2.2	1.4	0.6	-1.2	0.4	0.3	-1.0	1.2	1.3	1.0	0.4	0.8	-0.1	1.2	0.5	1.2	1.5	1.2	1.2
Mean time to correctly identify matches	0.2	0.4	0.9	0.8	0.5	-0.6	0.6	0.1	-0.8	0.9	0.4	0.8	0.0	0.9	-0.5	0.4	-0.0	0.7	0.8	0.5	0.5
Heart disease (mother)	5.0	6.1	15.1	1.3	1.7	-2.2	3.0	2.1	3.4	1.6	3.9	1.3	3.6	2.8	3.9	2.2	2.3	1.0	1.3	1.9	1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	2.0	1.2	0.4	-1.0	0.1	0.2	-0.7	0.2	1.1	0.6	0.7	-1.1	0.0	1.1	0.1	1.4	1.2	1.1	1.1
Whole body fat mass	0.3	1.4	5.0	0.9	1.3	-1.0	1.4	1.8	0.5	1.9	2.2	1.4	1.1	0.1	0.9	1.0	0.6	0.3	0.8	0.9	0.9
Leg fat mass (right)	0.5	2.1	6.2	1.2	1.5	-1.3	1.7	1.9	0.4	2.3	2.5	1.8	1.3	0.3	1.0	1.4	0.8	0.7	1.2	1.4	1.4
Arm predicted mass (right)	0.7	3.4	18.4	-2.5	-0.5	1.3	1.4	0.0	4.3	-0.9	1.1	-1.1	1.5	1.7	2.6	-1.4	0.3	-2.1	-2.5	-1.8	-1.7
Pulse rate, automated reading	1.9	6.0	9.6	-2.3	-3.0	2.7	-2.4	-2.8	-0.6	-2.4	-1.2	-3.1	-2.6	-1.2	-2.0	-2.6	-2.9	-3.0	-2.5	-2.5	-2.6
Alcohol intake frequency.	1.5	3.5	6.4	1.4	2.2	-2.0	2.4	1.3	1.2	2.5	1.3	2.1	2.0	1.4	2.1	2.1	2.3	0.3	1.6	1.8	1.9
Comparative height size at age 10	5.2	28.5	64.3	-7.3	-5.0	6.5	-2.3	-3.5	5.7	-6.1	-2.0	-6.0	-1.6	0.1	0.8	-6.6	-3.0	-6.7	-8.0	-7.1	-7.1
Number of full sisters	1.0	1.2	2.6	1.4	0.8	-1.5	0.9	0.6	-0.4	1.0	1.6	0.9	1.0	0.4	0.4	1.4	1.2	0.9	1.6	1.2	1.3
Suffer from ‘nerves’	0.2	0.2	1.1	0.2	0.1	-0.5	1.0	-0.9	0.4	0.5	0.0	0.1	0.6	0.6	0.6	0.3	-0.4	-0.4	0.4	0.4	0.4
Overall health rating	1.3	2.8	5.5	1.6	2.1	-1.9	1.2	1.5	-0.2	2.3	1.5	2.2	1.1	-0.3	0.6	2.1	2.0	1.2	2.0	1.9	1.9
Chest pain or discomfort	0.3	0.4	1.9	-0.1	-0.4	-0.2	0.2	-0.4	1.4	0.3	-0.0	-0.3	1.0	-0.6	1.2	0.3	0.6	-1.0	-0.2	-0.1	0.1
Had major operations	0.4	0.4	2.2	0.2	0.3	-0.3	0.8	0.8	1.5	0.3	0.4	-0.1	1.1	0.2	1.3	0.4	0.7	-0.4	-0.2	0.3	0.2
Age at last live birth	2.7	4.0	7.8	-1.8	-1.7	1.8	-2.3	-1.8	-2.1	-2.3	-2.3	-1.6	-2.8	-1.9	-2.7	-1.9	-2.3	-1.1	-1.2	-1.6	-1.7
Family relationship satisfaction	0.6	0.7	4.1	-1.0	-0.4	0.8	-0.4	-0.3	0.1	-2.0	-0.6	-0.7	-0.8	-0.6	-0.6	-1.2	-0.6	-0.6	-0.9	-1.0	-1.0
Leg pain on walking	0.3	0.4	2.0	0.2	0.7	-0.6	0.3	1.4	-0.5	-0.1	0.3	0.8	0.1	0.4	-0.2	0.5	0.5	1.4	0.7	0.5	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	2.5	-1.1	-0.5	0.6	-0.9	-0.3	1.6	0.1	-0.7	-0.7	0.2	-0.9	1.1	-0.2	0.5	-0.9	-1.1	-0.8	-0.6
Commuting to job workplace: Car/motor vehicle	1.0	1.1	2.9	0.5	1.0	-0.9	1.0	0.5	1.4	0.8	1.7	0.7	1.3	1.6	1.4	0.9	1.0	0.7	0.6	0.9	0.9
Illness, injury, bereavement, stress in last 2 years	1.1	1.3	2.5	-1.4	-1.3	1.3	-1.0	-1.3	0.4	-1.1	-0.6	-1.3	-0.6	-1.6	-0.3	-1.3	-0.8	-0.8	-1.4	-1.5	-1.4
Medication: Aspirin	0.8	1.1	2.3	0.9	1.1	-1.0	1.1	1.0	1.0	1.4	1.5	0.9	1.1	-0.7	1.2	1.2	1.1	-0.2	0.7	0.8	0.8
Supplements: Vitamin C	1.0	1.1	5.2	1.0	1.5	-0.5	1.2	2.3	1.2	-0.0	1.3	1.2	1.2	0.8	1.2	0.6	1.1	0.4	0.2	0.4	0.3
Knee pain experienced in last month	1.0	1.6	3.9	0.5	1.7	-1.2	0.9	2.0	0.9	1.4	1.6	1.5	1.2	-0.1	1.3	1.4	1.5	0.9	0.9	1.0	1.1
Hypertension (Self-reported)	4.5	12.5	29.3	3.1	4.1	-3.8	3.9	3.8	1.5	3.6	5.4	4.0	3.5	2.8	3.1	3.7	3.2	2.0	3.3	3.5	3.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	2.4	-0.5	-0.8	0.7	-1.0	-0.9	-0.7	0.3	-0.6	-0.7	-0.6	-1.5	-0.8	-0.5	-0.7	-0.6	-0.5	-0.5	-0.4
Illnesses of father: Heart disease	1.7	2.4	4.7	-1.6	-1.9	1.7	-1.8	-2.2	-0.0	-2.1	-0.4	-2.0	-1.3	-1.1	-0.8	-1.5	-1.6	-1.4	-1.7	-1.5	-1.5
Illnesses of siblings: Diabetes	0.2	0.2	1.1	-0.1	0.2	-0.4	-0.0	1.0	0.8	0.4	0.4	0.0	0.6	-0.5	0.5	0.7	0.7	-0.4	0.2	0.0	0.2
Smoking status: Previous	0.1	0.2	0.5	0.2	0.2	-0.5	0.3	0.3	-0.3	0.6	-0.2	0.2	0.2	-0.2	-0.2	0.4	-0.2	0.7	0.6	0.6	0.5
Forced expiratory volume in 1-second (FEV1), predicted	3.5	7.2	16.2	-4.0	-2.1	3.1	-1.8	-2.0	3.0	-3.0	-2.2	-2.8	-0.9	-1.8	0.7	-2.8	-0.9	-3.1	-4.0	-3.4	-3.4
Whole body fat-free mass	0.7	3.9	23.3	-2.3	-0.0	1.1	1.8	0.8	4.8	-0.6	1.4	-0.6	1.9	1.9	3.1	-1.2	0.8	-1.9	-2.4	-1.6	-1.5
Leg fat-free mass (right)	0.4	2.4	11.2	-0.7	1.0	-0.2	2.1	1.5	3.3	0.5	2.2	0.6	2.1	2.2	2.6	0.3	1.2	-0.5	-0.6	-0.1	-0.1
Arm fat percentage (left)	2.1	8.5	14.7	3.6	3.1	-3.2	2.3	3.2	-1.5	3.8	3.6	3.6	1.7	0.8	0.5	3.3	1.6	2.8	3.6	3.5	3.4
Average weekly red wine intake	0.7	1.0	5.1	-0.3	0.8	0.0	1.5	1.5	2.3	-0.0	-0.4	0.5	1.2	1.3	1.6	-0.1	0.9	-0.1	-0.6	-0.1	-0.2
Handedness (chirality/laterality): Left-handed	1.6	2.0	4.8	-1.2	-1.5	1.4	-1.4	-0.7	2.2	-1.3	-0.4	-1.6	0.3	-1.8	0.9	-0.9	0.0	-1.9	-2.0	-1.7	-1.7
Mood swings	0.1	0.1	0.6	-0.0	-0.3	-0.0	-0.3	-0.7	0.1	0.6	-0.5	-0.3	0.1	-0.8	-0.1	0.2	0.5	-0.3	0.0	0.1	0.1
Loneliness, isolation	0.9	1.3	2.4	1.2	1.2	-1.2	1.4	0.8	-0.5	1.2	0.2	1.5	0.5	1.4	0.4	1.0	0.3	1.6	1.4	1.3	1.4
Long-standing illness, disability or infirmity	2.2	3.3	6.2	2.0	1.5	-2.2	1.3	1.7	-0.9	2.2	2.1	1.7	0.9	1.0	0.5	2.3	0.9	2.3	2.5	2.3	2.3
Ever had bowel cancer screening	0.2	0.3	1.2	0.1	0.3	-0.6	0.5	-0.1	-0.3	0.2	1.1	0.2	0.6	-0.4	0.0	0.7	-0.2	0.7	0.6	0.5	0.6
Diabetes diagnosed by doctor	0.4	0.6	3.9	0.7	-0.2	-0.1	-0.9	0.0	-2.0	0.2	1.0	0.1	-0.9	-1.0	-1.3	0.3	-1.0	0.5	0.6	0.3	0.2
Ever had stillbirth, spontaneous miscarriage or termination	3.3	3.6	7.4	-2.2	-2.2	1.9	-2.0	-1.9	-0.7	-1.1	-2.0	-1.9	-1.8	-2.7	-1.5	-1.9	-1.1	-2.3	-1.7	-2.0	-1.9
Friendships satisfaction	0.6	0.7	3.9	-0.8	-0.9	0.5	-0.3	-1.1	-0.4	-2.0	-1.0	-1.1	-0.8	0.4	-0.6	-1.0	-1.0	0.4	-0.3	-0.5	-0.5
Qualifications: nursing, teaching	0.8	1.2	2.9	-1.1	-0.8	1.2	-0.8	-1.4	-0.1	-1.7	-1.4	-0.8	-1.0	0.4	-0.8	-1.4	-1.4	-0.6	-1.2	-1.1	-1.2
Commuting to job workplace: Walk	1.4	1.5	3.1	-1.0	-0.4	1.4	-1.4	-0.1	-1.4	-1.6	-1.5	-0.2	-1.7	-1.1	-1.8	-1.3	-1.3	-0.1	-1.0	-1.3	-1.3
Eye problems/disorders: Cataract	1.3	1.5	2.8	1.0	1.7	-1.1	1.3	0.8	1.0	1.4	0.5	1.7	1.6	0.1	1.3	1.1	1.7	1.4	0.9	1.2	1.2
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	3.9	1.0	0.2	-0.8	0.0	-0.2	-1.5	0.3	-2.0	0.3	-0.5	0.3	-0.9	0.6	0.0	1.2	1.2	1.0	0.9
Medication for cholesterol	3.4	5.1	11.9	-2.3	-2.3	2.6	-2.3	-1.9	-0.4	-2.0	-3.5	-2.3	-2.1	-2.1	-1.7	-2.6	-1.9	-1.7	-2.4	-2.6	-2.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	7.0	8.2	13.2	3.1	3.2	-3.2	3.2	3.4	0.1	2.3	3.2	3.2	2.2	3.6	1.9	2.7	2.0	2.7	3.1	3.2	3.2
Back pain experienced in last month	0.1	0.2	0.6	0.5	0.6	-0.4	0.1	-0.1	-0.8	0.3	-0.1	0.6	-0.2	-0.6	-0.4	0.3	0.1	0.1	0.5	0.6	0.5
Mineral and other dietary supplements	0.3	0.4	1.3	1.0	0.1	-0.7	0.3	0.1	0.4	0.5	1.1	-0.0	0.8	0.5	0.8	0.8	0.6	0.0	0.6	0.8	0.6
Breast cancer (self-reported)	0.4	0.5	1.3	-0.7	-0.5	0.7	0.4	0.5	0.5	-1.1	-0.6	-0.7	-0.3	1.1	-0.1	-1.0	-0.6	-0.6	-0.9	-0.8	-0.9
Asthma (self-reported)	0.2	0.4	1.3	0.7	0.6	-0.4	-0.6	0.4	-1.1	0.3	0.7	1.0	-0.2	-0.2	-0.6	0.6	-0.3	0.4	0.7	0.5	0.5
Osteoporosis (self-reported)	1.7	2.1	4.5	1.4	1.4	-1.6	2.1	1.1	0.2	1.7	-0.5	1.5	1.3	1.2	1.1	1.3	0.9	2.1	1.5	1.7	1.7
Osteoarthritis (self-reported)	2.2	2.9	7.0	1.4	1.8	-1.8	1.3	2.1	-0.5	1.6	2.6	1.9	1.1	2.0	0.7	1.8	1.3	1.9	1.9	1.8	1.9
Medication: Aspirin	0.5	0.6	1.2	0.5	0.8	-0.7	0.9	0.9	1.1	0.9	1.0	0.5	0.8	-0.5	1.1	0.8	1.0	-0.3	0.4	0.5	0.4
Medication: Gliclazide	0.3	0.3	1.2	-0.1	-0.2	0.5	-0.4	-0.5	-0.7	-0.5	-0.6	-0.3	-0.6	-0.1	-0.9	-0.5	-1.1	0.0	-0.3	-0.4	-0.6
Illnesses of father: None of the above (group 1)	1.1	1.3	2.7	-1.5	-1.5	1.2	-0.5	-1.2	0.5	-1.2	-1.5	-1.6	-0.6	0.2	-0.2	-1.4	-0.8	-1.2	-1.3	-1.4	-1.4
Smoking status: Current	0.2	0.3	0.9	0.8	0.9	-0.4	0.1	0.5	0.0	0.5	0.7	0.8	0.1	-0.5	0.3	0.6	0.6	0.2	0.4	0.4	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.8	-0.4	-0.0	0.1	0.2	0.1	0.8	0.3	-0.6	-0.2	0.3	-0.6	0.3	-0.2	0.9	-0.3	-0.4	-0.3	-0.3
Whole body water mass	0.6	3.7	22.8	-2.1	0.1	0.9	2.0	0.9	4.8	-0.4	1.5	-0.5	2.0	2.0	3.1	-1.0	1.0	-1.7	-2.2	-1.4	-1.3
Leg predicted mass (right)	0.5	2.5	11.3	-0.6	1.0	-0.3	2.1	1.5	3.4	0.6	2.2	0.7	2.1	2.2	2.7	0.3	1.3	-0.5	-0.6	-0.0	0.0
Arm fat mass (left)	1.6	6.4	14.1	2.7	2.6	-2.7	2.8	3.0	0.0	3.2	3.8	2.9	2.2	1.4	1.4	2.7	1.6	2.1	2.7	2.8	2.7
Number of self-reported non-cancer illnesses	2.5	4.3	12.1	2.2	2.1	-2.3	1.6	1.5	0.1	2.6	3.5	2.2	1.8	1.3	1.3	2.5	1.4	1.7	2.3	2.2	2.4
Average weekly champagne plus white wine intake	2.7	3.7	7.5	-1.7	-2.0	2.2	-1.7	-1.4	-1.2	-2.3	-1.6	-1.7	-2.4	-1.0	-2.0	-2.6	-2.7	-1.3	-1.9	-2.0	-2.0
Miserableness	0.2	0.3	2.9	-0.4	0.8	-0.1	0.8	0.7	0.5	-0.2	0.6	0.5	0.1	1.7	0.4	-0.1	-0.0	0.2	-0.1	0.1	0.1
Guilty feelings	0.3	0.5	2.3	-0.6	-0.1	0.6	-0.0	0.5	1.5	-0.4	1.0	-0.4	0.3	-0.6	1.0	-0.5	-0.3	-1.0	-1.0	-0.7	-0.7
Wears glasses or contact lenses	0.4	0.4	1.6	-0.4	-0.8	0.3	-0.6	0.3	-1.3	-0.2	0.9	-0.5	-0.9	-0.3	-1.2	-0.2	-0.8	-0.4	-0.0	-0.3	-0.3
Ever taken oral contraceptive pill	2.4	2.7	5.5	-2.2	-1.8	1.6	-0.8	-1.3	1.9	-1.9	-1.6	-2.3	-0.3	-0.7	0.6	-1.5	-0.6	-2.0	-2.2	-1.9	-1.9
Hearing aid user	1.4	1.5	6.7	0.9	1.4	-1.1	1.5	1.3	-1.0	0.7	1.1	1.5	0.1	2.6	-0.1	0.7	-0.1	2.0	1.3	1.1	1.1
Mother’s age at death	0.7	0.9	3.5	1.3	1.2	-0.8	0.8	1.9	0.3	0.1	0.4	1.2	1.0	0.7	0.6	0.8	0.8	1.3	0.7	0.8	0.7
Financial situation satisfaction	2.5	3.1	5.3	-2.0	-1.4	2.0	-1.6	-1.0	-0.9	-1.9	-2.3	-1.6	-2.2	-0.8	-1.8	-2.0	-1.8	-1.6	-1.7	-2.1	-2.1
Tinnitus: Yes, now most or all of the time	0.6	0.7	2.1	-0.1	-1.4	0.5	-0.9	-1.0	-1.2	-0.2	-0.3	-1.2	-1.1	-0.1	-1.4	-0.5	-1.2	-0.7	-0.2	-0.5	-0.4
Commuting to job workplace: Public transport	1.0	1.2	2.6	-1.2	-0.9	1.3	-1.0	-0.3	-0.3	-1.3	-0.9	-0.9	-1.1	-1.6	-0.8	-1.2	-1.2	-1.1	-1.2	-1.4	-1.3
Eye problems/disorders: Glaucoma	0.4	0.5	2.7	-0.4	-0.9	0.4	-0.9	-0.7	0.3	-0.1	-1.2	-0.9	0.0	-1.6	0.1	-0.1	0.3	-0.7	-0.5	-0.5	-0.5
Medication: Blood pressure	1.5	2.9	11.1	1.5	1.8	-1.9	1.9	1.1	-0.0	1.4	3.3	1.7	1.4	2.0	1.0	1.9	1.1	0.9	1.8	1.8	1.8
Pain type(s) experienced in last month: Hip pain	3.2	4.1	6.8	2.0	2.1	-2.2	2.6	1.8	1.3	1.8	2.2	1.9	2.5	1.5	2.0	2.0	2.3	1.9	1.8	2.0	2.0
Supplements: Fish oil (including cod liver oil)	0.6	0.7	1.5	-0.8	-0.6	0.9	-0.7	-0.6	-0.6	-1.0	-1.1	-0.6	-1.1	-0.5	-1.1	-0.9	-1.2	-0.4	-0.8	-1.0	-1.0
High cholesterol (Self-reported)	1.5	2.7	6.6	-1.1	-2.1	1.1	-2.4	-2.0	-1.8	-0.4	-0.1	-2.0	-1.9	-2.6	-2.0	-0.8	-1.7	-1.8	-0.6	-1.0	-1.0
Medication: Bendroflumethiazide	7.0	10.6	25.5	3.1	3.5	-3.5	3.4	3.0	1.2	2.7	5.0	3.5	3.4	3.5	2.8	3.6	2.6	2.6	3.1	3.3	3.4
Medication: Paracetamol	0.2	0.3	1.5	-0.7	-0.1	0.4	0.4	-0.3	0.5	-0.3	-1.2	-0.4	-0.1	0.7	0.3	-0.5	-0.6	-0.5	-0.6	-0.3	-0.4
Medication: Lisinopril	0.3	0.4	2.5	-0.5	-0.2	0.6	-0.6	0.1	0.9	-0.3	0.6	-0.4	-0.0	-0.6	0.3	-0.2	0.1	-1.6	-0.9	-0.8	-0.8
Medication: Atorvastatin	0.2	0.3	1.1	-0.6	-0.6	0.4	-0.8	-1.0	-0.1	0.9	-0.5	-0.4	-0.1	-0.3	-0.1	-0.2	0.0	-0.9	-0.4	-0.4	-0.2
Illnesses of father: High blood pressure	1.4	1.8	4.4	1.4	1.5	-1.2	-0.1	0.4	-1.5	1.6	1.9	1.7	0.2	0.5	-0.5	1.6	0.7	2.1	1.7	1.4	1.4
Alcohol drinker status: Never	1.2	1.4	4.8	-0.1	1.2	-0.7	1.1	0.6	2.0	1.5	-0.4	1.1	1.6	1.1	1.7	0.9	2.2	-0.9	0.2	0.4	0.5
Ever smoked	0.1	0.1	0.6	-0.4	0.2	0.3	-0.3	0.1	-0.2	0.4	-0.4	0.0	-0.4	-0.8	-0.4	-0.1	-0.4	-0.0	-0.2	-0.3	-0.3
Basal metabolic rate	0.5	3.0	18.1	-1.9	0.1	0.8	1.8	0.9	4.3	-0.2	1.6	-0.4	1.8	1.6	2.8	-0.9	0.8	-1.7	-2.0	-1.3	-1.2
Leg fat percentage (left)	0.5	1.9	4.6	1.6	1.5	-1.5	1.2	1.7	-1.0	2.1	1.6	1.8	0.6	0.1	-0.0	1.5	0.4	1.1	1.7	1.6	1.6
Arm fat-free mass (left)	0.6	3.3	18.5	-2.3	-0.4	1.1	1.6	0.3	4.3	-0.8	1.2	-1.0	1.6	1.6	2.7	-1.3	0.4	-2.0	-2.3	-1.6	-1.6
Number of operations (self-reported)	3.3	4.9	8.2	1.9	2.5	-2.2	2.8	2.9	0.7	2.0	1.8	2.5	1.9	2.5	1.9	2.0	2.1	2.4	2.0	2.3	2.3
Average weekly beer plus cider intake	0.6	0.9	2.5	0.9	0.7	-1.0	0.9	0.3	0.1	1.5	1.6	0.8	0.9	0.2	0.5	1.1	1.1	0.7	1.0	1.1	1.0
Irritability	0.2	0.3	0.7	-0.6	-0.5	0.1	-0.8	-0.8	-0.5	-0.8	-0.5	-0.6	-0.5	0.2	-0.7	-0.0	-0.6	0.5	-0.1	-0.2	-0.2
Risk taking	0.2	0.4	1.7	0.5	0.1	-0.3	-0.1	0.2	0.9	0.3	1.3	0.0	0.7	-0.9	1.0	0.5	0.8	-0.0	0.1	0.5	0.5
Ever had prostate specific antigen (PSA) test	0.8	0.9	3.5	-0.9	-0.7	1.0	0.1	-0.2	0.6	-1.7	-1.9	-0.8	-0.1	0.5	-0.1	-1.3	-0.7	-0.5	-1.2	-1.1	-1.2
Fractured/broken bones in last 5 years	0.2	0.3	2.6	-0.6	-0.6	0.2	-0.6	0.2	-0.2	-0.4	1.6	-0.5	-0.2	-0.1	-0.3	-0.1	-0.3	-0.6	-0.1	-0.2	-0.2
Age started oral contraceptive pill	0.1	0.1	0.7	-0.4	-0.2	0.0	0.4	-0.1	0.1	-0.9	0.2	-0.3	0.3	0.6	0.1	-0.3	-0.4	0.6	-0.1	-0.1	-0.1
Diastolic blood pressure, automated reading	1.0	3.0	15.4	0.2	0.7	-0.8	1.1	0.3	3.9	1.4	1.3	0.4	2.6	-1.4	3.4	1.3	2.8	-1.3	-0.4	0.5	0.5
Ever depressed for a whole week	0.5	0.6	1.8	-1.3	-0.4	0.6	0.3	-0.1	1.3	-0.8	-0.9	-0.7	0.1	0.6	0.7	-0.7	0.1	-0.6	-1.0	-1.0	-0.8
Unable to work because of sickness or disability	2.9	3.8	8.3	2.0	1.9	-2.0	1.8	1.8	-2.3	2.0	0.5	2.3	0.3	2.9	-0.7	1.7	0.8	2.5	2.7	2.2	2.2
Commuting to job workplace: Cycle	0.4	0.5	1.7	-0.9	-1.3	0.5	-0.4	-1.1	-0.7	-0.3	-0.2	-0.9	-0.6	0.1	-0.8	-0.8	-0.9	0.3	-0.4	-0.5	-0.5
Myopia	0.1	0.2	0.9	-0.0	0.1	0.1	-0.3	1.0	-0.5	-0.4	0.3	0.4	-0.5	-0.6	-0.5	0.1	-0.6	0.7	0.0	0.0	0.1
Vascular/heart problems diagnosed by doctor	4.3	11.7	27.2	-2.4	-3.8	3.4	-3.8	-3.7	-2.8	-3.6	-5.2	-3.5	-4.0	-2.1	-4.0	-3.4	-3.8	-1.1	-2.6	-3.1	-3.2
Cholesterol lowering medication	0.4	0.6	1.5	1.2	-0.1	-0.8	0.0	-0.4	-1.1	1.0	1.2	0.1	0.1	-0.1	-0.2	1.0	-0.1	0.2	1.1	1.0	1.0
Medication: Omeprazole (e.g. Zanprol)	2.9	3.6	7.2	-2.7	-2.1	2.2	-1.7	-1.5	0.8	-2.1	-1.1	-2.2	-1.1	-1.6	-0.5	-1.8	-1.6	-2.2	-2.4	-2.4	-2.2
Pain experienced in last month	0.2	0.3	3.1	0.2	0.3	-0.2	0.5	0.1	0.5	-0.0	0.1	0.3	0.6	1.8	0.4	0.2	0.0	0.2	0.2	0.1	0.1
Supplements: Calcium	0.3	0.3	1.8	0.3	0.5	-0.5	0.3	1.1	-0.7	0.5	-1.3	0.6	-0.3	-0.1	-0.4	0.3	0.1	0.4	0.7	0.4	0.5
Basal cell carcinoma (self-reported)	0.8	0.9	3.6	0.7	1.0	-0.9	0.8	1.6	-0.2	0.6	0.8	1.0	0.6	1.9	0.4	0.8	0.7	0.9	0.9	0.9	0.9
Heart attack/myocardial infarction (self-reported)	0.8	1.0	3.8	-0.8	-0.8	0.5	-0.8	-0.8	1.9	0.7	1.0	-1.1	0.8	-1.3	1.3	0.0	0.7	-1.4	-1.0	-0.6	-0.6
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	2.7	0.8	1.2	-1.1	1.2	0.9	1.3	0.8	1.1	1.0	1.6	-0.2	1.6	1.2	1.6	0.8	0.8	1.0	1.0
Heart disease (siblings)	1.0	1.2	2.2	0.6	0.8	-1.3	1.1	1.1	0.9	0.5	0.7	0.9	1.5	0.4	1.4	1.2	1.4	1.5	1.0	1.1	1.2
Alcohol drinker status: Previous	0.2	0.2	1.7	0.0	0.4	-0.2	0.8	-0.2	-0.0	0.5	-0.4	0.5	0.1	1.3	0.1	0.0	0.1	0.0	0.2	0.0	0.2
Pack years of smoking	0.3	0.4	0.9	-0.3	-0.4	0.7	-0.2	-0.6	-0.6	-0.5	-0.4	-0.5	-1.0	0.8	-0.7	-0.8	-0.8	-0.9	-0.6	-0.7	-0.8
Impedance of whole body	5.8	29.6	38.3	-5.3	-5.7	6.2	-5.9	-5.5	-0.6	-5.8	-5.8	-6.0	-5.0	-5.2	-3.6	-5.9	-4.8	-5.6	-6.0	-6.0	-6.2
Leg fat mass (left)	0.6	2.4	6.2	1.4	1.7	-1.5	1.9	2.0	0.4	2.4	2.5	1.9	1.5	0.7	1.1	1.5	0.9	0.7	1.3	1.5	1.5
Arm predicted mass (left)	0.7	3.3	18.6	-2.3	-0.4	1.1	1.7	0.3	4.3	-0.8	1.1	-0.9	1.6	1.6	2.7	-1.4	0.5	-2.0	-2.4	-1.6	-1.6