Hub : Genes

VLDLR

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adrenal Gland 0.3421 0.0988 1.0e-03 0.162 NA 0.189 NA 0.179 1.9e-06 NA 2.4e-07 NA 5.3e-07
2 GTEx Artery Tibial 0.4951 0.0452 0.0e+00 0.479 NA 0.506 NA 0.504 5.6e-42 NA 3.0e-45 NA 4.6e-45
3 GTEx Nerve Tibial 0.2332 0.0577 3.7e-05 0.151 NA 0.166 NA 0.161 8.1e-11 NA 8.2e-12 NA 1.7e-11
4 GTEx Thyroid 0.2470 0.0460 5.5e-09 0.121 NA 0.157 NA 0.157 1.7e-09 NA 4.5e-12 NA 4.8e-12
5 GTEx Whole Blood 0.1960 0.0500 1.1e-04 -0.002 NA 0.052 NA 0.017 6.5e-01 NA 1.3e-05 NA 8.9e-03
6 METSIM Adipose 0.0378 0.0181 2.1e-02 -0.001 0.003 0.002 0.007 -0.001 6.1e-01 9.9e-02 1.4e-01 2.9e-02 4.1e-01
7 YFS Blood 0.1708 0.0269 0.0e+00 0.016 0.094 0.114 0.100 0.077 3.9e-06 4.9e-29 4.1e-35 5.3e-31 4.5e-24
8 TCGA Esophageal Carcinoma 0.2620 0.1040 8.3e-03 0.020 0.020 0.045 NA 0.052 7.4e-02 7.4e-02 1.5e-02 NA 9.8e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 1.0 1.6 6.4 -1.2 2.5 1.2 0.7 -0.3 -1.7 0.3 -0.1
Bipolar Disorder or Schizophrenia 0.6 1.4 3.9 -0.6 1.8 1.5 0.3 -0.8 -2.0 1.0 -0.3
Depressed Affect (Nagel 2018) 0.4 0.9 3.0 0.1 0.1 -1.7 -0.4 -0.2 -0.6 1.3 1.3
Depression (Nagel 2018) 0.8 1.2 6.0 0.2 -1.2 -2.4 -1.2 0.3 -0.3 0.5 -0.2
Intelligence (Savage-Jansen 2018) 0.2 0.7 3.3 -0.7 -0.6 -0.5 0.3 0.0 0.1 -0.9 -1.8
Neuroticism (Nagel 2018) 0.2 0.5 2.8 -0.1 -0.4 -0.9 0.2 0.7 -0.0 0.0 1.7
Schizophrenia (2018) 0.3 0.5 1.5 0.2 0.3 0.9 -0.2 -0.8 -1.1 1.2 -0.3
Schizophrenia vs Biploar Disorder 0.7 0.9 2.1 0.8 -1.4 -0.2 -1.4 -0.9 0.6 -1.0 0.6
Worry (Nagel 2018) 0.3 0.7 1.4 -0.2 -0.7 -0.1 1.2 0.9 -0.3 -1.2 1.1
Alzheimer’s Disease (in mother) 0.8 1.0 3.5 -1.1 0.0 0.5 0.3 -0.2 -1.9 -0.7 1.5
Alzheimer’s Disease (in father) 1.3 1.4 4.2 -1.5 -1.6 -0.7 2.0 -0.4 -0.7 1.1 -0.2
Alzheimer’s Disease (including proxy) 1.0 1.5 6.5 -0.8 -1.4 -0.2 0.3 -1.3 -2.5 -0.7 0.6
Crohns Disease (2017) 0.4 0.8 2.7 0.9 0.9 0.4 -0.9 0.6 -0.1 1.6 -0.9
Irritable Bowel Disease (IBD) 0.4 0.9 2.2 0.6 -1.3 -0.8 -1.0 0.5 0.5 1.5 -1.1
Ulcerative Colitis (UC) 1.1 2.1 9.3 -0.0 -3.0 -1.9 -0.8 0.3 1.4 1.1 -0.3
Major Depression (MDD) 0.8 1.0 5.0 -0.6 -0.5 -2.2 0.0 0.1 -0.6 1.0 0.7
Reaction Time 0.9 1.7 5.1 1.5 -0.7 -1.7 -2.3 -1.0 -0.2 -1.2 0.8
Verbal and Numeric Reasoning (VNR) 0.5 1.1 6.1 -1.2 0.6 -0.0 0.7 0.8 -0.0 -0.2 -2.5
Breast Cancer 0.5 1.3 3.8 -0.5 -1.0 -1.9 0.8 1.2 1.7 -0.5 -0.0
Ovarian Cancer 1.1 1.5 5.7 -0.9 0.9 -0.6 1.2 1.1 1.2 0.1 2.4
Prostate Cancer 2.3 3.3 10.3 1.3 -3.2 -3.0 -1.7 0.4 1.3 0.2 0.0
Age at First Birth 1.3 2.0 5.9 1.1 -0.8 -2.4 -2.3 -0.9 0.1 0.3 -1.4
Bipolar Disorder (2011) 1.6 1.6 4.3 0.2 1.4 1.4 -0.6 1.0 -1.8 2.1 0.0
Body Mass Index (BMI) (2010) 0.3 0.3 1.0 0.1 0.9 -0.7 -0.1 0.1 0.5 -1.0 0.4
Coronary Artery Disease (CAD) 0.8 1.0 2.7 0.3 0.6 1.6 -1.1 -1.6 -0.8 -0.4 0.3
Crohns Disease (2012) 0.8 1.3 4.5 0.6 1.4 0.6 -0.9 0.6 -0.6 1.4 -2.1
Mean Putamen Volume 1.3 1.5 3.7 1.0 1.5 -0.1 -1.9 0.9 -1.8 1.1 0.4
Fasting Glucose 1.1 1.3 4.1 1.4 2.0 1.9 -0.6 -0.5 -0.3 0.2 -0.4
HbA1C 0.4 0.5 1.5 0.3 0.6 0.2 -0.6 -1.2 0.2 -0.5 1.1
HDL Cholesterol 0.8 1.3 3.6 -1.1 -0.7 -1.7 -0.8 1.0 1.9 0.3 -0.6
LDL Cholesterol 2.0 3.2 11.2 -0.0 -1.8 -3.1 -0.2 1.1 3.3 -0.2 0.3
Lupus 0.1 0.2 0.8 0.6 0.6 0.0 0.0 0.0 -0.2 -0.9 0.4
Neuroticism (2016) 0.7 1.1 3.7 1.9 -0.4 -1.7 -0.5 0.4 0.6 0.1 0.9
Primary Biliary Cirrhosis 0.7 1.0 1.9 -1.4 -1.4 0.2 1.0 -0.1 0.7 0.8 1.4
Rheumatoid Arthritis 0.9 1.2 3.9 0.4 2.0 1.8 -0.4 0.5 -0.8 0.7 0.9
Schizophrenia (2014) 0.4 1.0 2.6 -0.6 0.4 0.7 0.3 -1.6 -1.3 1.5 0.5
Triglycerides 0.7 1.2 4.2 0.3 1.5 1.1 0.3 -1.1 -2.0 -0.5 0.6
Type 2 Diabetes (T2D) (2012) 0.4 0.4 1.5 0.3 1.2 -0.0 -0.4 -0.4 -0.6 -0.9 0.3
Ulcerative Colitis 0.7 1.0 4.9 -0.4 -2.2 -1.0 -0.1 -0.3 0.7 0.4 -0.9
Blood Eosinophil Count 1.6 12.1 26.6 -4.2 0.9 0.7 3.5 4.2 0.3 5.2 4.6
Blood Platelet Count 1.4 16.0 82.8 0.5 1.0 2.1 0.7 6.2 0.1 9.1 0.8
Blood Red Count 0.6 5.8 12.9 -1.7 2.4 2.0 2.5 3.5 -0.8 3.6 -1.2
Blood White Count 2.4 17.5 38.3 -4.6 2.1 3.1 3.9 5.8 -1.4 6.2 4.0
Heel T-Score 0.1 0.8 4.4 -0.3 0.5 1.2 0.3 0.3 -2.1 -0.3 -0.4
BMI 0.3 1.8 2.9 1.2 1.7 1.6 -0.3 -1.5 -1.6 -1.7 -0.3
Height 0.1 1.4 3.0 1.3 1.3 -0.5 -0.9 0.2 -1.1 -1.7 1.5
Waist Hip Ratio (WHR) 0.5 2.1 12.9 -1.1 -3.6 -0.8 0.4 -0.2 0.8 -0.9 -0.2
Systolic Blood Pressure 1.7 8.5 23.4 4.8 2.1 1.9 -4.5 -1.8 -0.9 -1.0 -3.3
Smoking Status 0.3 0.7 1.8 -0.2 1.2 0.9 1.0 -0.5 0.1 -0.5 -1.3
Allergy or Eczema 0.4 0.9 3.5 -0.2 -0.0 0.8 -0.1 1.8 0.4 1.9 -0.2
Cardiovascular Disease 1.6 5.2 19.7 4.4 1.2 0.2 -3.8 -1.4 -0.9 -0.5 -1.7
Hypothyroidism (self reported) 1.6 3.6 11.4 -0.4 -2.1 -1.1 -0.3 -3.4 2.6 -1.7 1.4
Respiratory disease 0.3 0.8 4.8 -0.3 0.3 0.7 0.5 -0.1 -0.2 2.2 0.5
Type 2 Diabetes (T2D) (2018) 1.2 2.2 7.9 0.2 1.1 -0.3 1.3 -2.1 0.7 -2.8 1.2
Lung FEV1/FVC ratio 0.2 0.9 3.3 -0.7 -1.2 -1.2 0.5 0.2 0.0 -1.8 -0.6
Lung FVC 0.8 3.9 10.6 -0.1 1.3 3.3 0.9 2.5 -2.5 2.4 -0.3
Neuroticism 0.4 0.9 5.9 0.2 -0.0 -0.3 -0.3 0.3 -0.5 -0.6 2.4
Chronotype (morning person) 0.2 0.6 1.4 0.2 -0.2 1.0 0.1 1.2 -0.2 -1.2 -0.9
Hair Pigment 0.0 0.5 1.7 0.3 -1.1 -0.4 0.6 -0.1 1.3 -0.3 -0.9
Tanning 0.0 0.4 1.4 -0.5 -0.1 -1.2 0.1 0.4 0.1 0.6 0.9
Hand grip strength (left) 0.8 2.0 6.2 1.3 -1.0 0.0 -1.6 0.4 2.1 0.3 -2.5
Number of treatments/medications taken 0.2 0.4 1.0 0.1 0.6 -0.9 -1.0 -0.3 0.8 0.4 0.6
Average weekly spirits intake 1.3 1.6 5.0 -1.9 -0.3 -1.3 2.2 0.6 1.0 0.5 1.0
Sensitivity / hurt feelings 0.2 0.3 0.8 -0.5 0.4 0.7 0.6 0.9 0.5 -0.1 0.1
Frequency of depressed mood in last 2 weeks 0.6 0.8 3.9 0.2 -0.1 -2.0 0.2 1.5 0.3 0.0 -0.3
Hearing difficulty/problems: Yes 0.5 0.8 1.9 -0.7 1.2 1.2 -0.3 0.2 -1.0 -0.3 1.4
Relative age of first facial hair 0.3 0.6 1.6 -0.8 -0.1 0.6 0.5 -0.0 0.9 -1.0 1.2
Other serious medical condition/disability diagnosed by doctor 1.6 2.0 6.4 -1.2 -1.4 -1.6 -0.1 -2.5 0.3 -1.5 1.2
Ever used hormone-replacement therapy (HRT) 0.3 0.4 2.5 0.1 0.1 0.5 0.4 0.5 -0.1 -1.6 0.1
Ever had hysterectomy (womb removed) 1.0 1.2 3.3 0.7 -0.7 -1.5 -1.8 0.7 -0.1 0.9 -1.3
Systolic blood pressure, automated reading 1.5 4.3 14.6 3.0 1.4 0.9 -3.8 -1.7 -0.8 -1.3 -1.9
Eye problems/disorders: Diabetes related eye disease 1.7 1.9 5.8 1.1 -0.3 -1.3 -0.5 -2.4 1.9 -1.6 0.5
Angina 0.6 0.8 2.0 -0.7 -0.7 -0.9 0.5 0.4 1.0 -1.1 1.4
Medication for hormone replacement therapy 0.3 0.4 1.3 -0.6 -0.5 -0.4 0.6 -1.1 -0.4 -0.0 -0.7
Vitamin and mineral supplements 1.4 1.8 5.2 0.6 -0.5 -1.7 -1.2 -0.6 1.0 -1.8 2.3
Supplements: Zinc 1.5 1.6 5.4 -0.1 2.3 0.5 -0.6 0.7 -1.8 1.7 -0.3
Medication: Co-codamol 0.5 0.6 1.2 -0.1 -0.7 -0.8 0.5 -1.1 0.0 -1.1 1.0
Medication: Metformin 0.4 0.6 1.8 -0.4 -0.2 -1.1 0.1 -0.3 1.2 -0.4 1.4
Diabetes (father) 1.1 1.4 2.9 1.3 1.4 1.1 -1.1 -1.7 -0.8 -0.4 0.9
Diabetes (mother) 0.8 1.0 6.4 1.0 -0.4 -0.5 -0.5 -0.2 0.2 -2.5 -0.0
Severe depression (siblings) 0.6 0.7 1.6 -0.8 0.8 0.7 -0.4 0.5 0.2 1.2 -1.3
Pack years adult smoking proportion 0.6 0.9 2.3 -0.7 0.7 0.8 1.0 0.1 1.3 -1.0 1.5
Impedance of leg (right) 0.2 0.8 3.2 -1.8 0.0 -0.8 1.2 0.1 0.2 -0.5 0.8
Leg fat-free mass (left) 0.0 0.2 0.5 0.7 -0.0 0.5 -0.0 -0.2 -0.6 -0.3 0.7
Trunk fat percentage 0.1 0.2 0.5 -0.1 0.4 -0.5 0.2 0.3 -0.7 -0.6 0.6
Hand grip strength (right) 0.8 2.2 4.9 2.1 -1.3 -0.4 -1.4 0.9 1.8 0.7 -2.2
Townsend deprivation index at recruitment 1.6 2.2 7.5 -0.3 2.7 2.6 1.4 0.1 -1.0 0.9 -0.3
Current tobacco smoking 0.6 0.9 3.6 -0.5 0.9 -0.2 -0.8 -1.3 0.7 -1.9 0.2
Average weekly fortified wine intake 0.5 0.6 1.8 -0.8 -1.0 -0.9 -0.3 -1.4 0.1 0.4 -0.7
Maternal smoking around birth 0.3 0.5 1.4 0.2 0.2 1.1 1.2 0.2 -0.3 1.0 -0.4
Fed-up feelings 0.6 1.0 4.9 0.1 -0.1 -0.8 0.3 1.4 0.1 0.9 2.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.0 4.1 0.4 -0.3 -2.0 -1.3 0.7 -1.1 0.4 0.5
Relative age voice broke 0.5 0.8 1.4 -1.2 -0.9 -1.2 0.1 -1.0 0.7 -0.6 0.9
Taking other prescription medications 0.4 0.6 2.2 0.3 0.7 -0.2 -0.6 -0.2 0.5 -1.0 1.5
Age when periods started (menarche) 0.3 0.7 3.2 0.4 -0.2 -0.0 0.1 -1.5 0.2 -0.3 1.8
Bilateral oophorectomy (both ovaries removed) 0.7 0.8 3.2 -0.0 -0.2 -0.2 -0.8 1.3 -0.5 1.8 -0.8
Heel bone mineral density (BMD) T-score, automated (left) 0.8 1.7 7.6 1.4 -0.3 0.7 -1.7 -0.0 -2.8 -0.1 -0.8
Tinnitus: Yes, but not now, but have in the past 1.3 1.4 7.1 -0.2 0.6 0.9 0.7 0.4 1.5 -0.2 2.7
Qualifications: CSEs or equivalent 0.3 0.4 0.8 0.8 0.4 0.9 -0.8 0.5 -0.2 0.9 -0.1
Serious illness, injury or assault to yourself 1.5 1.8 5.7 -1.1 1.1 -0.0 0.1 -2.4 -1.6 -1.3 1.4
High blood pressure 0.8 2.3 5.2 2.3 1.7 -0.1 -1.7 -2.0 -0.2 -1.8 -0.7
Hayfever, allergic rhinitis or eczema 0.4 1.0 2.6 0.3 0.8 1.6 -0.4 1.1 -1.0 1.4 -0.0
Multivitamins +/- minerals 1.6 2.0 7.1 0.1 0.3 1.5 0.8 1.3 -0.9 1.8 -2.7
Stomach or abdominal pain in last month 0.5 0.7 2.3 -1.1 0.6 0.0 -0.4 0.8 1.5 0.6 -0.6
Supplements: Glucosamine 0.7 1.0 4.8 -1.0 -0.7 -2.2 0.4 0.5 0.9 0.0 -0.5
Diverticular disease/diverticulitis (self-reported) 1.1 1.3 2.4 -0.4 -1.6 -1.3 -1.4 -1.4 -0.8 -1.2 0.1
Medication: Atenolol 0.3 0.4 1.6 -0.2 0.8 -1.3 -0.6 0.0 0.4 -0.1 -0.2
Medication: Levothyroxine sodium 1.4 2.4 9.5 0.4 -1.6 -1.6 -0.2 -3.1 1.4 -1.1 1.0
Sitting height 0.3 1.8 8.3 -1.0 -0.6 0.2 0.8 1.5 -0.5 -1.3 2.9
Chronic bronchitis/emphysema (father) 1.1 1.2 5.1 -2.3 -0.6 -0.7 1.3 0.4 -0.3 -1.3 0.5
High blood pressure (mother) 0.5 0.7 3.1 1.2 0.5 0.1 -1.8 0.7 0.3 0.2 0.1
Body mass index (BMI) 0.1 0.4 1.5 1.2 0.5 0.4 -0.3 -0.1 -0.4 0.0 -0.8
Impedance of leg (left) 0.2 0.9 2.4 -1.5 -0.5 -1.5 0.8 0.5 0.6 -0.8 0.6
Leg predicted mass (left) 0.0 0.2 0.5 0.7 0.0 0.5 -0.0 -0.1 -0.5 -0.2 0.7
Trunk fat mass 0.1 0.2 0.7 0.1 0.4 -0.1 0.4 0.4 -0.5 -0.6 0.8
Waist circumference 0.0 0.1 0.4 0.2 -0.4 0.0 0.1 -0.5 -0.2 -0.6 -0.1
Number of incorrect matches in round 0.5 0.8 2.2 0.7 -0.7 -1.5 -0.0 0.0 -1.1 -1.4 -0.5
Past tobacco smoking 0.8 1.4 3.4 1.6 -1.2 -1.1 -1.9 -0.2 0.3 -0.8 1.4
Alcohol usually taken with meals 0.1 0.2 0.9 -0.2 -0.5 1.0 -0.0 -0.4 -0.8 0.0 -0.1
Nervous feelings 0.9 1.6 6.0 -0.8 0.9 0.7 1.1 2.5 1.3 -0.1 1.4
Frequency of tenseness / restlessness in last 2 weeks 0.2 0.4 1.7 0.3 0.2 -0.3 0.6 1.3 0.5 0.4 0.5
Hearing difficulty/problems with background noise 1.0 1.6 4.9 -2.0 1.5 2.2 0.9 -0.3 -0.5 -0.3 0.7
Hair/balding pattern: Pattern 2 1.2 1.6 5.4 0.3 -2.3 -2.0 -0.2 0.2 1.8 -0.1 0.2
Had menopause 1.1 1.3 2.9 -1.6 -1.7 -1.4 1.4 -0.1 0.0 -0.5 1.0
Had other major operations 0.8 1.0 4.0 0.9 -1.0 -0.3 -0.4 -0.2 1.0 0.9 -2.0
Forced vital capacity (FVC) 0.3 1.1 4.4 -0.5 0.1 1.7 0.2 0.3 -2.1 -0.3 0.9
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.4 9.0 0.6 -0.4 0.9 -0.9 0.1 -3.0 0.3 -0.1
Ever unenthusiastic/disinterested for a whole week 0.7 0.9 2.6 -0.4 0.9 1.6 -0.4 1.3 -0.2 0.4 1.1
Qualifications: None of the above 0.2 0.5 1.7 0.2 0.4 0.4 0.5 1.0 1.3 0.4 0.9
Financial difficulties in last 2 years 0.2 0.3 0.8 0.3 -0.2 0.9 -0.6 0.3 0.4 0.4 -0.7
Mouth/teeth dental problems 0.3 0.5 2.2 0.4 -0.4 -0.4 -0.4 -0.1 -0.7 0.5 -1.5
Heart attack 0.8 1.1 3.9 -1.2 -0.3 -0.9 0.5 -0.2 1.4 -2.0 -0.3
Allergy 1.2 2.7 7.7 -0.3 -1.7 -2.5 0.1 -1.8 1.0 -2.8 -0.5
Pain all over the body in last month 0.4 0.5 0.9 0.5 0.4 -0.8 -0.8 -0.4 0.9 -0.9 0.5
Diabetes (self-reported) 0.5 0.8 2.4 0.2 1.5 -0.0 0.4 -0.5 0.9 -1.6 0.2
Hayfever/allergic rhinitis (self-reported) 0.4 0.6 1.4 -0.4 -0.8 -0.8 0.2 1.1 0.4 1.2 -0.6
Medication: Ramipril 0.6 0.8 3.5 0.6 0.4 -0.2 -0.5 -0.3 1.9 -0.4 -1.4
Medication: Simvastatin 0.6 0.9 2.6 0.8 1.6 1.2 -1.0 0.1 -0.6 -1.0 -0.4
Fluid intelligence score 0.7 1.4 7.1 -0.7 0.7 0.3 0.1 1.6 0.6 -0.0 -2.7
Illnesses of siblings 0.5 0.7 2.2 -1.1 0.6 0.6 0.9 0.6 -0.6 0.4 1.5
Neuroticism score 0.7 1.4 6.6 0.1 1.0 0.5 0.4 1.3 -0.8 -1.1 2.6
Weight 0.0 0.2 0.5 0.5 0.2 0.2 0.2 -0.0 -0.4 -0.7 0.6
Impedance of arm (right) 0.5 2.2 6.2 -2.5 -1.5 -1.4 0.5 -0.8 0.3 -1.1 2.2
Arm fat percentage (right) 0.0 0.2 0.6 0.3 0.5 0.2 -0.1 -0.5 -0.3 -0.7 0.4
Trunk fat-free mass 0.1 0.4 1.0 1.0 0.1 0.9 0.2 -0.1 -0.2 -0.7 0.7
Hip circumference 0.1 0.5 2.4 0.4 1.5 0.5 0.2 -0.3 -0.6 -0.5 0.3
Time employed in main current job 0.4 0.5 2.0 0.8 0.4 -0.4 0.6 0.4 0.2 1.4 -0.7
Alcohol intake versus 10 years previously 0.8 1.3 5.7 0.9 1.4 2.4 0.7 -0.2 -0.8 0.6 0.2
Father’s age at death 0.7 1.0 2.0 0.8 1.4 0.5 -0.0 -1.4 -0.5 -1.4 1.1
Worrier / anxious feelings 0.8 1.5 5.4 -1.0 0.2 0.8 1.8 0.4 -0.7 -1.2 2.3
Frequency of tiredness / lethargy in last 2 weeks 1.2 1.9 4.7 -1.4 2.2 0.7 1.6 0.7 -0.6 -0.5 2.2
Falls in the last year 0.8 1.0 2.0 -0.6 -1.2 -1.2 1.4 -0.2 1.3 -0.8 0.7
Hair/balding pattern: Pattern 3 1.3 1.9 8.3 -0.3 2.9 2.2 1.0 -0.5 -0.7 -0.0 0.5
Number of live births 0.9 1.3 3.8 -1.6 -0.5 0.9 2.0 -0.4 1.2 -0.7 -0.8
Forced expiratory volume in 1-second (FEV1) 0.1 0.5 2.1 -0.2 -0.5 0.9 0.1 0.6 -1.5 -0.6 0.4
Pulse rate 1.1 1.8 3.8 1.3 1.0 1.4 -0.6 -1.3 -0.8 -1.9 -1.9
Happiness 0.6 0.7 3.8 -1.3 -0.1 -0.3 0.3 -0.2 -0.0 -0.1 2.0
Noisy workplace 0.7 0.9 2.3 0.0 -0.5 -0.6 1.5 1.2 1.4 0.8 0.1
Qualifications: A levels/AS levels or equivalent 0.4 0.9 3.2 -1.0 -0.3 0.4 -0.1 1.3 0.7 0.5 -1.8
Serious illness, injury or assault of a close relative in last 2 years 1.1 1.3 3.4 0.7 1.1 1.1 0.0 -0.1 -1.9 -1.4 1.5
Mouth/teeth dental problems: Dentures 1.1 1.9 6.1 -1.5 2.5 0.8 1.4 1.8 0.6 -0.7 0.1
Asthma 1.0 1.9 5.4 -0.3 1.5 2.0 0.7 0.7 -1.0 2.3 1.2
Medication: Ibuprofen (e.g. Nurofen) 1.1 1.4 4.4 -1.4 0.5 -0.0 1.8 0.1 -0.9 -0.7 2.1
Medication: Cholesterol lowering 0.4 0.7 1.7 0.5 1.0 0.2 -1.1 0.6 1.3 0.2 -1.1
Depression (self-reported) 1.1 1.3 4.8 -0.5 2.0 0.1 0.2 2.2 -1.0 0.3 -0.5
Medication: Lansoprazole 1.7 1.9 5.9 -1.6 -0.4 -1.1 2.4 1.9 1.0 -0.9 0.2
Prospective memory result 1.3 1.6 5.4 1.8 -0.5 0.4 -2.3 -1.8 -0.6 0.5 -0.2
Lung cancer (father) 0.4 0.5 1.8 0.6 -0.3 -1.1 -0.2 -0.5 1.3 -0.0 0.1
Illnesses of mother 0.5 0.6 1.3 -0.5 -1.0 -1.2 1.1 -0.6 -0.7 -0.1 0.6
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.5 2.2 0.5 -0.2 1.5 -0.5 0.3 -0.9 -0.7 -0.4
Pulse wave Arterial Stiffness index 1.0 1.2 4.3 -0.1 -1.7 0.3 -0.4 -2.1 0.7 -1.0 0.3
Impedance of arm (left) 0.4 1.7 6.5 -2.5 -1.0 -1.0 0.5 -0.4 -0.1 -0.5 2.1
Arm fat mass (right) 0.1 0.2 0.5 0.4 0.3 0.4 0.2 -0.3 -0.7 -0.7 0.4
Trunk predicted mass 0.1 0.4 1.0 1.0 0.0 0.9 0.3 -0.1 -0.2 -0.6 0.7
Standing height 0.2 1.6 6.9 -1.1 -0.9 -0.4 1.0 0.3 -0.1 -1.5 2.6
Length of working week for main job 0.6 0.7 4.4 -0.2 0.3 -0.1 0.5 2.1 -0.5 0.6 0.5
Exposure to tobacco smoke at home 0.7 0.8 2.8 0.4 -1.2 -1.3 0.7 -0.1 1.7 0.1 0.2
Breastfed as a baby 1.1 1.3 4.2 -2.0 0.4 0.2 1.2 0.5 -1.2 0.4 1.7
Tense / ‘highly strung’ 0.5 0.9 5.6 -0.2 0.6 0.0 0.9 2.4 0.1 -0.1 0.0
Seen doctor (GP) for nerves, anxiety, tension or depression 0.6 1.0 4.1 -0.1 2.0 0.4 0.0 1.0 -1.5 -0.2 0.5
Hair/balding pattern: Pattern 4 0.3 0.7 1.9 -0.1 0.7 1.4 -0.1 0.6 -1.2 -0.5 1.0
Birth weight of first child 0.6 1.1 2.7 -0.7 1.0 0.4 1.7 1.4 0.2 0.8 1.4
Peak expiratory flow (PEF) 0.7 1.6 3.8 -1.6 0.7 2.0 1.1 0.7 -1.1 -0.5 1.6
Pulse wave reflection index 0.7 0.9 2.6 -0.0 -1.3 1.1 -0.1 -1.2 0.2 -0.7 1.6
Ever highly irritable/argumentative for 2 days 0.3 0.4 1.0 0.3 1.0 0.5 0.0 0.7 0.2 1.0 0.6
Loud music exposure frequency 0.6 0.7 2.0 -0.8 1.4 1.0 1.0 0.4 -0.2 0.3 0.4
Qualifications: O levels/GCSEs or equivalent 0.5 0.8 2.4 -0.7 -0.1 0.1 1.5 1.2 0.0 0.4 -1.6
Mouth/teeth dental problems: Bleeding gums 1.4 1.9 5.4 2.3 -0.7 1.0 -2.2 -1.6 0.3 -0.2 0.6
Blood clot in the leg (DVT) 0.3 0.4 1.1 0.6 -0.2 0.3 -0.5 0.6 -1.1 0.7 0.7
Medication: Paracetamol 0.4 0.6 1.1 -0.1 0.2 0.9 0.8 1.0 -0.1 1.1 1.1
Headache pain in last month 0.7 1.2 5.6 -1.3 0.1 0.0 0.5 0.9 1.1 0.3 2.4
Medication for cholesterol, blood pressure or diabetes 0.7 1.1 4.1 -0.5 -0.9 1.0 1.1 -0.7 -2.0 0.1 1.2
Glaucoma (self-reported) 0.8 1.0 3.3 -1.8 1.1 0.8 0.4 -0.7 0.3 0.9 1.2
Gout (self-reported) 0.3 0.5 1.1 -0.9 -0.3 -0.7 0.0 1.0 -0.6 0.8 -0.4
Hypothyroidism/myxoedema (self-reported) 2.3 4.4 14.3 -0.0 -2.1 -1.2 -0.2 -3.8 2.6 -2.7 0.9
Medication: Amlodipine 0.4 0.5 2.0 0.8 0.1 0.5 -1.4 -0.3 0.5 0.4 -0.8
Medication: Ventolin 100micrograms inhaler 0.8 1.0 2.8 1.7 -0.7 1.1 -1.0 -0.9 0.8 0.8 -0.6
Birth weight 0.5 1.2 2.7 -1.1 -0.2 -1.5 1.4 1.0 0.5 -0.4 1.6
Chronic bronchitis/emphysema (mother) 0.5 0.5 1.6 0.5 -1.1 -0.1 1.3 0.2 0.4 0.1 -1.0
High blood pressure (siblings) 0.8 1.2 4.1 1.5 -0.7 -0.2 -1.4 -0.8 0.2 -0.3 -2.0
Forced vital capacity (FVC), Best measure 0.3 1.2 6.3 -0.3 0.5 2.5 0.0 0.1 -1.6 -0.3 0.6
Body fat percentage 0.0 0.2 0.6 0.1 0.6 -0.2 0.2 -0.1 -0.8 -0.5 0.4
Leg fat percentage (right) 0.0 0.1 0.7 0.2 0.8 0.1 0.3 -0.4 -0.4 -0.1 -0.1
Arm fat-free mass (right) 0.1 0.5 2.2 1.5 0.3 0.6 -0.1 0.4 -0.8 -0.7 -0.1
Exposure to tobacco smoke outside home 1.0 1.4 6.7 2.6 -0.0 -1.6 -0.9 0.1 -0.5 -0.7 -0.5
Comparative body size at age 10 0.6 1.5 4.2 0.9 -0.6 0.0 -0.8 1.6 1.9 2.0 0.3
Number of full brothers 1.2 1.5 4.0 -1.2 0.5 1.7 1.1 2.0 0.9 1.2 -0.6
Worry too long after embarrassment 0.8 1.3 5.5 -0.4 0.2 1.9 -0.3 0.6 -0.7 -0.2 2.3
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.2 0.7 -0.0 0.4 -0.8 -0.2 0.1 0.3 -0.7 0.6
Wheeze or whistling in the chest in last year 0.4 0.7 1.3 -1.0 0.8 1.1 1.0 -0.7 -0.1 1.0 0.8
Number of children fathered 1.6 1.9 9.0 -0.0 -0.6 -1.0 0.3 1.7 1.2 3.0 0.4
Reason for reducing amount of alcohol drunk: Health precaution 0.8 0.9 3.3 1.0 -1.8 -0.8 -0.6 -0.2 -0.6 1.0 -0.9
Age at first live birth 0.2 0.3 1.5 0.2 1.2 0.1 -0.4 -0.4 -0.0 -0.5 0.6
Pulse wave peak to peak time 0.9 1.1 4.5 0.0 1.7 -0.5 0.4 2.1 -0.6 0.8 -0.2
Health satisfaction 1.0 1.3 6.7 -0.2 -0.8 -0.2 -0.1 -0.1 2.6 0.0 1.7
Shortness of breath walking on level ground 1.1 1.3 6.0 1.1 -0.4 0.3 -0.3 1.3 2.5 0.6 -0.7
Qualifications: College or University degree 0.6 2.0 4.5 -2.1 -0.3 -0.6 1.7 -0.8 -1.1 -1.4 2.1
Eye problems/disorders: None of the above 1.1 1.3 4.6 2.1 -1.0 0.6 -0.6 1.8 0.9 0.3 -0.4
Mouth/teeth dental problems: Loose teeth 0.4 0.5 1.1 -0.9 -0.8 0.0 0.6 0.7 -0.7 0.5 1.1
Emphysema/chronic bronchitis 1.8 2.0 5.2 -1.4 1.7 1.7 1.7 -0.4 -0.5 2.3 0.3
Medication for pain relief, constipation, heartburn 0.5 0.8 5.2 0.2 0.1 0.7 0.1 -0.5 0.1 0.6 -2.3
Neck or shoulder pain in last month 0.8 1.1 3.0 -1.1 1.0 1.7 1.7 0.7 -0.1 -0.2 0.2
Medication: Blood pressure 0.6 1.1 2.8 0.5 0.8 -1.0 -1.3 0.1 1.6 0.3 -1.7
Angina (self-reported) 0.8 1.0 1.7 -0.6 -1.1 -1.3 0.3 0.6 1.3 -1.3 1.1
Migraine (self-reported) 2.3 2.9 8.1 2.4 0.5 -1.2 -2.9 1.9 1.8 -0.1 -0.5
Medication: Ibuprofen 1.5 1.8 4.7 -2.1 -0.0 -0.0 1.9 -0.2 -1.2 -0.6 2.2
Medication: Allopurinol 1.2 1.6 3.8 -1.0 -0.5 -1.2 0.8 1.8 1.5 1.9 -0.6
Medication: Omeprazole 2.3 2.7 9.7 1.2 -0.5 -1.6 -3.1 -1.6 1.0 -1.9 -0.4
Medication: Seretide 50 evohaler 0.2 0.3 1.3 -0.2 0.3 1.2 0.3 0.5 0.0 -0.6 0.1
Mean time to correctly identify matches 1.0 1.9 3.9 1.4 -0.4 -1.5 -2.0 -1.5 0.3 -1.6 1.6
Heart disease (mother) 0.6 0.7 1.8 1.2 0.4 -0.1 -1.3 -0.2 1.0 0.8 -0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.7 2.0 1.3 -0.7 0.7 -1.4 -0.5 -0.4 -0.6 -0.5
Whole body fat mass 0.0 0.2 0.4 0.4 0.6 0.1 0.2 0.1 -0.6 -0.5 0.5
Leg fat mass (right) 0.0 0.2 0.7 0.4 0.8 0.5 0.4 -0.0 -0.5 -0.3 0.2
Arm predicted mass (right) 0.1 0.5 2.8 1.7 0.2 0.5 -0.1 0.8 -0.5 -0.5 -0.1
Pulse rate, automated reading 1.0 3.1 6.9 2.1 1.0 1.4 0.2 -2.1 -0.5 -2.6 -2.5
Alcohol intake frequency. 0.2 0.6 2.0 0.8 -0.0 0.2 -0.8 -0.7 0.5 -0.5 1.4
Comparative height size at age 10 0.2 1.3 7.5 0.7 -0.3 -0.5 -1.2 -0.6 -0.6 -2.7 -0.1
Number of full sisters 0.3 0.4 0.8 0.9 0.7 0.7 -0.9 0.5 0.5 -0.1 -0.2
Suffer from ‘nerves’ 0.6 1.0 5.6 0.8 -0.0 0.5 0.5 0.5 0.8 -2.4 0.6
Overall health rating 0.4 0.9 3.3 -0.5 1.1 0.3 0.5 -0.2 0.8 -1.8 1.2
Chest pain or discomfort 0.3 0.4 2.3 -0.2 0.5 0.5 0.3 -0.2 1.5 -0.3 -0.7
Had major operations 0.2 0.3 0.6 -0.4 -0.6 -0.4 -0.7 -0.1 -0.5 -0.8 0.1
Age at last live birth 0.5 0.7 2.7 -0.8 -0.5 0.3 0.5 -1.0 0.1 -1.6 0.8
Family relationship satisfaction 0.8 1.0 2.0 -1.0 -0.6 -1.1 0.4 1.4 0.2 1.1 1.4
Leg pain on walking 0.4 0.5 1.6 0.9 -0.6 -0.0 -0.5 0.2 1.3 0.2 0.9
Qualifications: NVQ or HND or HNC or equivalent 0.9 1.1 3.2 0.2 0.8 1.2 -1.8 -0.9 -0.9 0.9 1.0
Commuting to job workplace: Car/motor vehicle 2.0 2.3 8.0 1.5 -0.3 0.1 -1.2 2.5 -0.3 2.8 -0.4
Illness, injury, bereavement, stress in last 2 years 0.7 0.9 3.2 -0.4 -0.1 -0.4 -0.1 1.8 1.3 1.3 -0.7
Medication: Aspirin 0.4 0.5 1.7 -0.5 0.4 -0.7 -0.4 -0.2 1.3 -0.3 1.0
Supplements: Vitamin C 0.7 0.9 3.0 -0.9 1.2 -0.5 1.7 -0.2 -0.2 -0.5 -1.0
Knee pain experienced in last month 0.6 0.9 2.9 -0.2 -0.3 -0.8 1.7 0.6 1.3 -0.7 1.1
Hypertension (Self-reported) 0.8 2.3 6.1 2.5 1.4 -0.2 -2.0 -1.9 0.2 -1.4 -0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.2 1.4 4.9 0.4 2.0 -0.2 -2.2 -0.4 -0.2 -1.2 -0.1
Illnesses of father: Heart disease 0.6 0.8 2.4 0.3 1.3 0.7 -1.5 -0.6 -0.2 0.2 -1.2
Illnesses of siblings: Diabetes 0.3 0.4 1.2 0.2 -0.6 -0.5 -0.4 -1.1 0.8 0.2 -0.5
Smoking status: Previous 1.1 1.7 4.4 -1.7 -0.0 0.4 2.1 0.2 -0.9 1.5 -1.8
Forced expiratory volume in 1-second (FEV1), predicted 0.1 0.2 1.1 -0.0 -0.7 -0.4 0.2 0.0 0.2 -1.0 0.3
Whole body fat-free mass 0.1 0.3 1.3 1.1 -0.0 0.6 -0.1 -0.1 -0.5 -0.5 0.6
Leg fat-free mass (right) 0.0 0.2 1.1 1.0 -0.4 0.0 -0.5 -0.0 -0.3 -0.4 0.5
Arm fat percentage (left) 0.0 0.1 0.3 0.3 0.4 0.2 -0.1 -0.2 -0.5 -0.4 0.4
Average weekly red wine intake 1.1 1.6 7.2 -2.7 0.2 0.9 1.7 0.8 -0.9 0.5 -0.5
Handedness (chirality/laterality): Left-handed 2.0 2.4 6.1 -0.8 1.7 2.5 0.3 -2.0 0.9 -2.1 0.5
Mood swings 1.3 2.3 11.3 -1.1 1.3 -0.8 1.4 0.5 -1.0 -0.8 3.4
Loneliness, isolation 0.7 1.0 3.8 0.5 -0.2 -0.9 0.8 1.9 -0.3 1.2 -0.8
Long-standing illness, disability or infirmity 0.4 0.6 1.5 0.3 0.5 -0.5 0.3 -0.8 1.2 -1.1 1.0
Ever had bowel cancer screening 1.2 1.4 5.3 -0.9 1.5 1.2 -0.8 0.8 0.1 2.3 -0.3
Diabetes diagnosed by doctor 0.9 1.4 4.5 -0.2 0.9 -0.5 0.8 -1.1 1.0 -1.8 2.1
Ever had stillbirth, spontaneous miscarriage or termination 0.6 0.6 2.1 0.0 1.4 0.0 0.2 -1.1 -0.0 0.2 -1.3
Friendships satisfaction 0.7 0.8 3.2 -0.2 -0.8 0.5 0.2 1.8 0.2 1.1 1.1
Qualifications: nursing, teaching 0.5 0.8 2.5 -0.3 -1.6 -0.4 0.2 -1.1 0.7 0.5 -1.3
Commuting to job workplace: Walk 0.9 1.0 2.9 -1.4 -0.0 0.9 1.3 -0.6 -0.3 -1.7 0.1
Eye problems/disorders: Cataract 0.4 0.5 2.0 -0.8 0.8 0.4 0.3 -0.3 -1.4 0.2 0.2
Mouth/teeth dental problems: Mouth ulcers 0.4 0.7 1.5 -0.2 -1.2 -0.9 -0.8 1.0 0.7 0.9 0.2
Medication for cholesterol 2.4 3.6 10.1 -2.4 -1.1 -1.2 2.2 3.2 1.8 1.4 0.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.7 0.9 2.0 1.4 -1.0 -1.0 -0.9 -0.5 0.3 -1.4 0.3
Back pain experienced in last month 0.5 0.8 2.2 0.7 0.8 1.1 0.3 0.1 -0.7 -1.0 1.5
Mineral and other dietary supplements 0.8 1.1 3.0 0.8 0.6 0.8 0.0 -1.5 -0.9 -1.1 1.7
Breast cancer (self-reported) 0.8 0.9 2.3 -1.2 0.2 -0.2 -0.9 1.5 -1.3 0.0 1.0
Asthma (self-reported) 0.8 1.6 4.5 -0.2 1.4 1.6 0.5 0.5 -1.0 2.1 1.5
Osteoporosis (self-reported) 0.1 0.1 0.5 -0.1 0.1 0.4 0.4 -0.3 -0.7 0.2 -0.1
Osteoarthritis (self-reported) 1.4 1.8 7.0 -0.2 -1.9 -2.6 -0.1 0.5 1.8 -0.2 0.7
Medication: Aspirin 0.5 0.6 2.0 -0.6 0.1 -1.2 -0.7 -0.2 1.4 -0.1 0.9
Medication: Gliclazide 1.4 1.6 5.0 2.2 0.5 0.4 -1.7 -1.8 -0.4 -1.1 0.3
Illnesses of father: None of the above (group 1) 0.4 0.5 1.4 -0.8 -0.5 -0.2 0.9 0.4 0.7 0.0 1.2
Smoking status: Current 0.6 1.0 3.7 -0.4 1.4 0.2 -0.6 -1.1 0.9 -1.9 0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.7 2.4 0.4 0.5 1.3 -0.2 -0.0 -1.6 -0.1 -1.0
Whole body water mass 0.1 0.3 1.2 1.1 -0.0 0.5 -0.1 -0.2 -0.5 -0.5 0.5
Leg predicted mass (right) 0.0 0.2 0.9 1.0 -0.4 0.1 -0.4 -0.0 -0.3 -0.3 0.5
Arm fat mass (left) 0.1 0.2 0.5 0.5 0.3 0.4 0.3 -0.2 -0.7 -0.7 0.4
Number of self-reported non-cancer illnesses 1.3 2.2 7.3 2.1 0.6 -0.7 -2.7 -0.5 1.7 -0.2 -1.4
Average weekly champagne plus white wine intake 0.6 0.9 3.5 1.9 -0.1 0.9 -1.2 -0.6 -0.9 0.2 -0.3
Miserableness 0.3 0.5 1.7 -0.3 1.3 0.4 0.2 -0.1 -1.0 -0.1 1.1
Guilty feelings 0.5 0.8 3.9 -0.1 -0.5 -0.7 0.6 0.7 -0.8 -0.3 2.0
Wears glasses or contact lenses 0.6 0.6 2.6 0.0 -0.4 -0.5 0.2 -1.0 1.1 -1.6 0.1
Ever taken oral contraceptive pill 0.5 0.5 1.3 0.3 0.2 -0.6 0.2 -1.0 1.0 -0.7 1.2
Hearing aid user 1.0 1.2 4.9 -2.0 0.3 -0.1 2.2 -0.5 0.0 0.4 0.0
Mother’s age at death 0.6 0.7 2.7 -0.5 1.0 1.6 0.6 0.9 -0.5 0.4 -0.3
Financial situation satisfaction 0.5 0.6 3.3 1.8 0.6 0.1 -0.7 -0.7 -0.4 0.2 0.2
Tinnitus: Yes, now most or all of the time 0.8 1.0 2.8 -0.5 -0.7 -1.7 0.7 1.1 -0.4 1.6 0.1
Commuting to job workplace: Public transport 1.1 1.3 3.2 -1.8 0.5 0.1 0.7 -1.1 -1.3 -0.8 1.7
Eye problems/disorders: Glaucoma 0.5 0.6 2.9 -1.7 0.6 0.7 0.4 -0.1 0.2 0.7 0.5
Medication: Blood pressure 1.6 3.1 8.8 2.6 1.0 0.4 -2.5 -3.0 -0.7 -1.3 -0.3
Pain type(s) experienced in last month: Hip pain 0.7 0.9 2.2 -0.2 -0.6 -0.3 1.5 1.1 0.1 -1.2 1.4
Supplements: Fish oil (including cod liver oil) 1.2 1.5 4.5 -1.2 -0.6 -0.8 0.7 2.1 1.6 -0.1 -1.4
High cholesterol (Self-reported) 0.9 1.6 6.7 1.8 0.5 -0.4 -2.6 0.1 0.8 0.2 -1.1
Medication: Bendroflumethiazide 1.2 1.8 3.5 1.4 1.7 1.9 -1.9 -0.6 -1.2 0.4 -0.4
Medication: Paracetamol 0.2 0.3 1.1 0.1 0.1 1.0 0.5 0.6 0.1 0.6 0.5
Medication: Lisinopril 0.5 0.6 2.5 0.1 0.8 -0.0 -0.0 -1.6 -1.4 -0.1 -0.2
Medication: Atorvastatin 0.9 1.1 2.7 -0.3 -1.1 -1.1 -0.4 -1.6 1.5 0.8 0.8
Illnesses of father: High blood pressure 0.7 0.9 2.7 1.6 -0.1 0.1 -0.6 0.6 0.0 1.6 -0.9
Alcohol drinker status: Never 2.2 2.6 9.1 -0.6 -1.6 -0.9 -1.7 -0.5 1.1 -3.0 1.9
Ever smoked 0.5 0.8 1.8 -1.3 1.0 1.1 1.0 -0.8 -0.5 0.1 -0.9
Basal metabolic rate 0.0 0.3 0.8 0.9 0.1 0.5 0.1 -0.1 -0.4 -0.6 0.6
Leg fat percentage (left) 0.0 0.1 0.2 0.4 0.5 -0.3 0.0 -0.1 -0.1 -0.4 -0.1
Arm fat-free mass (left) 0.0 0.3 0.8 0.8 0.2 0.2 0.4 0.2 -0.4 -0.9 0.3
Number of operations (self-reported) 0.4 0.6 1.7 0.3 -0.6 -1.3 -1.1 0.1 0.4 0.1 -1.1
Average weekly beer plus cider intake 0.9 1.3 5.4 2.3 0.1 -0.1 -1.7 0.3 0.1 1.2 -0.6
Irritability 0.5 0.9 3.4 -0.4 -0.1 -0.6 -0.2 1.4 0.3 -1.2 1.8
Risk taking 0.7 1.0 3.4 -0.8 -1.1 -1.9 -0.3 -1.1 -1.2 -0.4 0.1
Ever had prostate specific antigen (PSA) test 1.1 1.2 3.6 0.2 0.9 0.3 -0.8 1.9 1.1 1.8 -0.4
Fractured/broken bones in last 5 years 0.6 0.8 1.6 -1.1 0.1 1.1 1.3 0.8 -0.6 1.2 -0.4
Age started oral contraceptive pill 0.7 0.8 1.8 -1.1 0.8 1.4 1.1 -0.1 -1.1 0.6 -0.3
Diastolic blood pressure, automated reading 1.4 4.4 12.5 3.5 0.7 0.2 -3.2 -2.3 -1.0 -1.3 -1.9
Ever depressed for a whole week 0.2 0.2 0.9 -0.1 0.2 0.3 -0.6 0.9 0.1 -0.4 0.2
Unable to work because of sickness or disability 0.4 0.5 1.7 0.4 0.8 0.4 -0.5 0.2 -0.6 -1.3 0.9
Commuting to job workplace: Cycle 1.3 1.6 4.0 -0.9 -0.7 -0.5 1.5 -1.7 0.7 -2.0 1.3
Myopia 0.6 0.9 2.5 -1.6 0.3 1.4 1.3 0.4 0.4 -0.6 -0.1
Vascular/heart problems diagnosed by doctor 0.6 1.7 3.6 -1.7 -1.4 0.3 1.4 1.9 0.0 1.7 0.2
Cholesterol lowering medication 0.6 0.9 3.0 1.2 0.5 0.2 -1.7 -1.5 -0.6 -0.4 0.3
Medication: Omeprazole (e.g. Zanprol) 1.4 1.8 6.5 0.5 -0.2 -1.3 -2.6 -1.9 0.6 -1.2 -0.3
Pain experienced in last month 1.2 1.9 5.2 0.4 -0.5 -0.5 -1.3 -1.9 -1.1 -1.8 -2.3
Supplements: Calcium 0.9 1.0 4.2 1.0 0.5 1.2 -0.5 -0.1 -0.5 2.1 -0.4
Basal cell carcinoma (self-reported) 1.9 2.3 7.9 -2.8 -0.6 0.0 2.5 0.4 -0.0 -0.2 1.8
Heart attack/myocardial infarction (self-reported) 0.8 1.1 5.0 -1.0 -0.3 -0.8 0.4 -0.2 1.2 -2.2 -0.4
Deep venous thrombosis (DVT) (self-reported) 0.3 0.4 1.1 0.4 0.1 0.3 -0.3 0.7 -1.0 0.7 0.9
Heart disease (siblings) 1.1 1.3 4.5 -1.1 -1.2 -2.1 1.1 -1.1 0.3 -0.7 0.6
Alcohol drinker status: Previous 0.6 0.6 2.1 -0.6 -0.3 -1.4 0.5 -1.3 0.4 -0.6 -0.1
Pack years of smoking 0.8 1.2 3.1 -0.8 0.9 0.9 1.2 -0.0 1.3 -0.9 1.8
Impedance of whole body 0.3 1.5 5.3 -2.3 -0.8 -1.5 0.9 0.3 0.2 -0.6 1.6
Leg fat mass (left) 0.0 0.1 0.3 0.5 0.6 0.2 0.4 0.3 -0.3 -0.4 0.1
Arm predicted mass (left) 0.1 0.4 1.8 1.3 0.3 0.4 0.2 0.1 -0.6 -0.6 -0.2