Hub : Genes

VPS41

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1380 0.0290 1.4e-10 0.095 0.109 0.116 0.119 0.115 1.2e-11 3.4e-13 5.7e-14 3.0e-14 6.7e-14
2 GTEx Adipose Subcutaneous 0.1110 0.0400 1.8e-03 0.020 NA 0.058 NA 0.036 9.0e-03 NA 1.5e-05 NA 6.1e-04
3 GTEx Artery Aorta 0.1570 0.0610 5.9e-03 0.002 NA 0.039 NA 0.033 2.5e-01 NA 3.1e-03 NA 6.5e-03
4 GTEx Artery Tibial 0.2278 0.0472 4.4e-08 0.038 NA 0.109 NA 0.083 5.4e-04 NA 7.0e-09 NA 4.8e-07
5 GTEx Cells Transformed fibroblasts 0.1530 0.0380 6.7e-07 0.103 NA 0.112 NA 0.073 4.0e-08 NA 1.0e-08 NA 3.7e-06
6 GTEx Lung 0.1669 0.0468 1.0e-04 0.127 NA 0.092 NA 0.122 6.2e-10 NA 1.7e-07 NA 1.4e-09
7 GTEx Nerve Tibial 0.2200 0.0493 4.0e-08 0.108 NA 0.140 NA 0.134 4.7e-08 NA 4.4e-10 NA 1.0e-09
8 METSIM Adipose 0.0823 0.0226 5.4e-06 0.029 0.045 0.043 0.040 0.032 2.9e-05 2.6e-07 4.3e-07 1.1e-06 1.1e-05
9 NTR Blood 0.0624 0.0133 1.0e-12 0.057 0.041 0.046 0.049 0.049 8.4e-18 3.7e-13 1.1e-14 1.7e-15 1.3e-15
10 ROSMAP Brain Pre-frontal Cortex 0.0429 0.0203 1.7e-02 0.034 0.010 0.008 0.015 0.019 3.2e-05 1.7e-02 3.0e-02 3.7e-03 1.5e-03
11 YFS Blood 0.1189 0.0202 0.0e+00 0.086 0.084 0.099 0.097 0.092 1.2e-26 4.3e-26 1.4e-30 4.3e-30 1.4e-28
12 TCGA Brain Lower Grade Glioma 0.0981 0.0406 6.7e-04 0.032 0.016 0.027 NA 0.019 1.2e-04 5.6e-03 4.2e-04 NA 2.8e-03
13 TCGA Lung Adenocarcinoma 0.0481 0.0233 1.2e-03 0.015 0.020 0.037 NA 0.032 6.6e-03 1.7e-03 3.0e-05 NA 1.1e-04
14 TCGA Prostate Adenocarcinoma 0.0410 0.0212 3.3e-03 0.006 0.012 0.009 NA 0.012 6.7e-02 1.9e-02 3.8e-02 NA 1.9e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 0.8 1.3 6.2 0.7 0.4 0.3 2.5 -0.1 0.9 0.5 0.5 0.7 1.2 1.9 -0.3 0.9 1.9
Bipolar Disorder or Schizophrenia 0.7 1.6 4.5 0.2 -1.2 0.2 1.3 -0.5 1.4 -0.2 0.2 1.2 2.0 1.2 -2.1 -1.1 2.0
Depressed Affect (Nagel 2018) 2.3 4.9 17.6 1.2 -1.3 -1.1 0.6 -3.9 -2.2 -3.1 -1.6 0.8 -2.3 0.9 -2.3 1.2 4.2
Depression (Nagel 2018) 1.9 2.9 12.7 1.1 -1.0 -1.3 2.3 -2.6 -0.1 -1.6 -0.5 1.1 0.2 1.5 -2.3 0.5 3.6
Intelligence (Savage-Jansen 2018) 1.5 4.5 25.4 2.3 1.1 1.2 -1.2 0.7 -1.2 -2.0 2.1 3.1 -1.3 -5.0 1.1 2.3 -0.4
Neuroticism (Nagel 2018) 2.1 5.0 18.3 1.0 -1.4 -1.9 0.5 -3.6 -1.9 -3.3 -1.6 0.4 -1.9 1.5 -2.8 0.6 4.3
Schizophrenia (2018) 0.7 1.4 6.6 -0.3 -1.9 0.0 -0.4 -0.6 1.0 -0.7 -0.1 1.0 1.6 0.1 -2.6 -1.8 1.1
Schizophrenia vs Biploar Disorder 0.7 0.9 2.1 -0.9 -1.3 0.4 -0.5 -1.4 -0.6 -0.7 -1.1 -0.5 -0.7 0.4 -1.5 -1.3 0.7
Worry (Nagel 2018) 1.3 2.8 9.5 0.2 -1.6 -1.1 -0.2 -2.7 -0.6 -2.5 -1.6 0.0 -0.2 1.8 -3.1 -0.6 2.5
Alzheimer’s Disease (in mother) 1.2 1.4 6.5 -0.6 0.0 -2.6 -1.1 -0.7 -1.4 -1.2 -1.2 -1.0 -1.7 -1.2 0.6 0.6 -0.7
Alzheimer’s Disease (in father) 0.5 0.6 2.3 1.2 0.3 1.5 -0.2 -0.7 -0.3 -0.4 0.1 1.1 -0.6 -0.8 -0.6 0.8 0.2
Alzheimer’s Disease (including proxy) 0.6 0.9 2.1 0.1 -0.2 -1.1 -0.9 -1.0 -1.3 -1.3 -1.0 -0.1 -1.4 -1.4 -0.3 1.0 -0.3
Crohns Disease (2017) 0.6 1.4 6.9 -1.7 0.2 0.4 0.1 -0.9 0.3 0.6 -1.6 -2.6 -0.2 1.7 1.1 -1.3 -0.4
Irritable Bowel Disease (IBD) 0.7 1.7 6.2 -1.4 1.3 1.1 0.6 0.2 0.8 1.5 -0.3 -2.5 0.2 2.5 1.7 -0.9 -0.0
Ulcerative Colitis (UC) 1.1 2.0 4.7 -0.6 2.2 1.3 1.3 1.0 1.3 1.8 1.0 -1.6 0.9 2.1 2.1 0.1 0.3
Major Depression (MDD) 2.5 3.0 9.5 2.7 0.6 0.9 2.1 -0.4 0.0 -0.5 2.0 3.1 0.2 -0.3 -1.7 2.6 2.4
Reaction Time 1.0 2.0 6.2 0.1 1.6 1.0 2.0 2.5 1.6 1.8 1.8 0.6 1.8 -0.3 0.5 0.1 -0.5
Verbal and Numeric Reasoning (VNR) 1.5 3.5 13.5 2.4 1.8 1.3 -0.4 0.6 -1.0 -1.9 1.7 3.1 -1.2 -3.7 0.6 2.2 -0.5
Breast Cancer 0.7 1.6 8.3 0.3 0.9 1.4 1.2 0.2 1.1 0.6 0.3 -0.4 0.9 2.9 1.2 1.3 2.0
Ovarian Cancer 1.0 1.3 6.7 1.1 1.1 1.3 1.4 0.2 0.2 0.1 1.2 1.1 0.2 -0.7 0.3 2.6 1.5
Prostate Cancer 0.4 0.6 1.7 0.4 0.4 0.2 -1.1 -0.8 -0.6 -0.6 -0.9 0.0 -1.0 0.1 0.7 1.0 1.3
Age at First Birth 0.8 1.1 3.3 -0.4 -1.1 0.1 -1.3 -0.3 -1.4 -1.2 -0.9 -0.1 -1.4 -1.8 0.3 -0.8 -1.5
Bipolar Disorder (2011) 0.6 0.5 1.8 -1.3 -0.3 -0.1 0.1 0.6 0.1 0.6 -0.7 -1.3 -0.0 0.4 0.5 -1.2 -0.9
Body Mass Index (BMI) (2010) 0.4 0.5 2.4 0.8 0.4 0.1 1.0 0.5 -0.2 0.3 0.4 0.4 -0.5 -1.6 -0.4 0.4 -1.1
Coronary Artery Disease (CAD) 0.6 0.8 3.5 -1.0 -1.1 -1.4 -1.9 0.5 -0.4 0.1 -0.7 -1.0 -0.3 0.6 0.6 -0.6 0.2
Crohns Disease (2012) 0.3 0.5 3.0 -1.1 0.3 0.1 -0.3 0.2 -0.2 0.2 -0.8 -1.7 -0.7 0.8 0.7 -0.2 -0.7
Mean Putamen Volume 2.2 2.5 10.4 3.2 1.0 -0.1 -1.2 0.3 -1.9 -0.7 1.6 2.1 -1.8 -1.0 -0.9 2.2 1.0
Fasting Glucose 1.1 1.3 4.8 0.3 1.9 0.6 0.1 1.5 -0.3 1.1 1.6 0.0 -0.7 0.1 1.4 2.2 -0.9
HbA1C 1.1 1.3 8.3 -0.7 -0.6 -1.0 -1.0 -0.3 0.1 1.0 -1.0 -0.9 -0.0 1.1 0.2 -1.6 -2.9
HDL Cholesterol 0.1 0.2 1.7 0.2 -0.0 0.1 -0.4 -0.1 -0.0 -0.1 0.4 0.4 0.1 0.1 -0.2 0.2 1.3
LDL Cholesterol 0.6 1.0 3.7 -0.3 -0.5 -1.6 -0.5 1.6 -0.4 0.8 0.2 -0.1 -0.4 -0.7 -0.3 -1.7 -1.9
Lupus 1.4 2.1 5.1 2.3 0.0 -2.3 0.0 -1.0 -1.4 -1.4 1.5 2.0 -1.4 -0.7 -0.3 1.3 2.2
Neuroticism (2016) 0.9 1.3 8.1 -0.5 0.2 -0.0 1.6 -2.0 0.5 -1.2 -0.8 -0.3 0.1 -0.0 0.3 0.6 2.8
Primary Biliary Cirrhosis 1.5 2.2 10.3 0.3 -0.9 -0.5 -0.2 -3.2 -1.2 -2.4 -1.2 0.1 -1.3 -0.2 -0.4 0.6 2.8
Rheumatoid Arthritis 0.6 0.9 3.3 1.1 -1.1 0.8 -1.8 -0.2 -0.7 -0.3 0.1 0.9 -0.5 1.2 -0.9 0.4 1.4
Schizophrenia (2014) 0.7 1.6 5.0 -0.9 -1.8 0.3 0.2 -0.8 1.4 -0.0 -0.6 0.1 2.0 1.0 -2.2 -2.1 1.0
Triglycerides 0.3 0.5 1.5 -0.4 0.5 0.0 1.2 0.3 0.7 1.2 -0.4 -0.2 0.9 0.6 0.5 -0.3 -0.8
Type 2 Diabetes (T2D) (2012) 0.4 0.4 1.3 1.0 0.2 -1.1 -0.7 0.1 -0.9 -0.0 0.8 0.8 -0.6 -0.2 -0.9 -0.1 0.2
Ulcerative Colitis 1.1 1.5 5.0 -0.2 1.8 1.4 1.1 1.4 0.9 1.5 1.0 -0.9 0.7 2.2 1.3 0.6 1.1
Blood Eosinophil Count 0.1 0.7 2.5 1.2 1.0 1.6 0.6 0.9 0.5 0.5 1.4 1.1 0.4 0.1 -0.7 0.0 0.3
Blood Platelet Count 0.2 2.5 8.5 1.0 2.9 0.7 2.0 1.5 1.8 1.0 1.9 0.4 1.6 0.6 1.8 1.8 1.0
Blood Red Count 0.1 0.8 2.3 -0.9 -0.6 -1.5 0.6 -1.3 -0.4 -0.9 -1.1 -1.3 -0.7 0.1 0.5 -0.2 1.0
Blood White Count 0.1 0.7 1.9 -1.2 1.3 -0.1 0.4 0.2 1.4 0.8 -0.7 -0.4 1.0 -0.0 1.2 1.1 0.3
Heel T-Score 0.2 1.9 6.9 -2.3 0.7 -2.6 -0.4 -0.7 -0.4 -0.0 -2.1 -2.1 -1.0 -0.9 0.6 -0.3 -1.7
BMI 0.3 1.8 5.1 1.8 2.2 -0.2 1.6 0.3 -0.8 0.1 1.8 0.9 -1.2 0.4 2.0 0.9 1.9
Height 0.1 1.1 2.5 1.1 -0.4 0.9 -1.0 -1.6 -1.1 -0.9 1.2 1.5 -1.2 -0.2 -0.7 0.9 1.1
Waist Hip Ratio (WHR) 0.1 0.6 2.1 -0.7 -0.7 -1.4 1.2 0.1 0.3 0.2 -0.5 0.4 0.7 -0.5 -1.4 -0.8 -0.1
Systolic Blood Pressure 0.1 0.6 3.5 -0.4 -0.0 0.2 -0.2 -0.7 0.2 -0.5 -0.1 -0.1 -0.0 0.8 1.5 0.9 1.9
Smoking Status 0.8 2.0 5.2 1.5 -1.6 0.0 -1.7 -2.0 -1.1 -1.4 -0.6 1.4 -0.9 -1.4 -2.3 -0.6 1.5
Allergy or Eczema 0.5 1.3 2.8 -0.8 -1.4 -1.4 -1.7 -0.4 -1.3 -1.0 -1.1 0.3 -1.1 -0.6 -1.2 -1.5 -0.9
Cardiovascular Disease 0.3 0.9 2.6 -0.6 0.3 -0.8 1.6 -0.4 1.3 0.1 -1.1 -0.7 1.2 1.0 0.0 -0.2 1.5
Hypothyroidism (self reported) 0.3 0.6 1.7 0.8 1.3 0.6 1.3 0.7 0.3 0.5 0.1 -0.3 0.2 1.2 -0.3 0.2 1.2
Respiratory disease 0.3 0.6 2.3 0.8 -0.9 -0.6 -1.5 -0.6 0.1 -0.7 -0.6 0.6 0.4 0.4 -1.5 -0.6 0.6
Type 2 Diabetes (T2D) (2018) 0.3 0.6 1.6 1.0 0.6 -0.6 1.1 0.3 -0.2 -0.2 0.6 1.3 -0.1 -0.3 -1.1 1.2 0.9
Lung FEV1/FVC ratio 0.6 2.9 6.6 1.4 -1.5 -2.2 -1.1 -0.5 -2.4 -2.6 -0.6 1.5 -2.4 -1.8 -2.4 0.3 0.8
Lung FVC 0.8 4.1 16.4 3.6 -0.0 0.4 -1.7 1.0 -1.6 0.1 4.0 3.0 -1.2 -0.2 -0.9 3.0 1.0
Neuroticism 1.7 4.0 12.3 0.4 -1.9 -1.1 -0.1 -3.0 -1.8 -3.5 -2.0 -0.0 -1.9 1.2 -2.3 0.1 3.4
Chronotype (morning person) 0.8 1.8 4.0 -1.2 -1.4 -1.7 -0.8 -1.3 -1.5 -1.3 -1.3 -2.0 -1.9 0.4 0.3 -1.5 -0.1
Hair Pigment 0.0 0.6 4.6 0.3 0.0 -0.5 -0.0 -2.1 -0.0 -1.2 -0.2 -0.3 -0.2 0.0 0.6 0.0 1.3
Tanning 0.2 2.8 10.9 3.3 -0.4 0.3 -0.2 -0.7 -1.4 -1.4 1.6 3.0 -1.1 0.1 -1.5 2.0 2.1
Hand grip strength (left) 1.8 4.7 21.3 2.8 -0.4 1.2 -4.6 -0.7 -2.8 -1.0 2.0 2.7 -2.7 -0.9 0.8 2.5 0.3
Number of treatments/medications taken 0.3 0.5 4.0 0.1 0.4 -0.6 0.8 -0.1 -0.0 0.1 -0.4 -0.7 -0.2 1.3 0.2 0.3 2.0
Average weekly spirits intake 0.9 1.1 4.9 1.5 -0.0 0.2 0.5 -0.7 -0.6 -0.5 0.1 1.0 -0.5 1.1 -1.6 1.2 2.2
Sensitivity / hurt feelings 0.7 1.2 3.3 -0.2 -1.3 -1.6 0.3 -1.6 -0.9 -1.1 -1.0 -0.4 -0.9 0.1 -1.7 0.0 1.8
Frequency of depressed mood in last 2 weeks 1.2 1.7 7.3 1.1 -0.4 -0.5 2.6 -1.9 0.1 -0.9 -0.0 0.8 0.2 0.7 -1.2 1.0 2.7
Hearing difficulty/problems: Yes 0.8 1.2 5.3 0.3 1.1 1.3 2.3 0.8 1.5 0.3 -0.2 0.5 1.6 0.4 0.6 1.1 0.3
Relative age of first facial hair 1.4 2.8 13.2 0.7 2.4 3.6 1.3 0.3 1.0 1.0 1.6 0.8 0.8 0.1 2.2 2.7 0.4
Other serious medical condition/disability diagnosed by doctor 1.1 1.4 3.8 1.0 -0.6 -1.9 0.6 -0.5 -1.4 -1.8 -1.1 0.4 -1.4 -0.3 -1.5 0.5 1.7
Ever used hormone-replacement therapy (HRT) 1.8 2.2 6.3 0.3 -1.5 -1.2 -1.4 -2.0 -1.2 -1.2 -1.6 -0.0 -1.0 2.5 -1.8 -0.6 2.3
Ever had hysterectomy (womb removed) 0.8 1.0 3.8 -0.9 -0.9 0.0 0.2 -1.4 0.4 0.0 -1.8 -1.0 0.2 1.9 -0.1 -0.7 1.0
Systolic blood pressure, automated reading 0.3 0.9 5.9 0.4 0.6 -0.2 -0.4 -0.8 -0.3 -0.9 0.3 0.7 -0.6 0.3 0.9 1.6 2.4
Eye problems/disorders: Diabetes related eye disease 2.1 2.3 7.3 0.2 2.7 1.9 2.4 1.2 0.8 1.2 1.3 -0.3 0.1 -0.5 2.7 1.9 0.1
Angina 0.5 0.7 2.3 -0.5 0.9 0.1 0.7 1.2 0.9 1.5 0.4 -0.8 0.9 1.2 0.7 0.5 -0.3
Medication for hormone replacement therapy 1.0 1.1 4.0 -0.3 0.2 0.7 1.3 -1.0 1.0 0.5 -0.8 -0.2 0.8 2.0 1.1 0.8 2.0
Vitamin and mineral supplements 0.3 0.4 1.8 0.7 0.5 1.4 -0.8 0.4 -0.2 0.6 0.4 0.0 -0.3 0.9 -0.2 0.1 0.6
Supplements: Zinc 0.5 0.5 2.5 -0.7 -0.5 -1.0 0.5 0.5 -0.2 -0.8 -0.4 0.5 0.1 -1.6 -0.6 -0.7 -1.0
Medication: Co-codamol 0.9 1.0 6.7 0.8 -1.2 -0.1 -1.1 1.2 0.2 -0.1 0.8 1.0 0.7 0.4 -2.6 -0.3 0.7
Medication: Metformin 0.7 1.0 3.2 0.6 1.4 1.1 1.5 0.0 0.8 0.5 0.1 1.1 0.7 0.1 -0.1 1.8 1.5
Diabetes (father) 0.8 1.0 3.0 -0.4 1.4 0.5 1.4 -0.9 -0.5 -0.2 -0.5 -0.3 -0.9 0.6 1.7 1.7 1.3
Diabetes (mother) 0.2 0.2 0.5 -0.3 0.1 0.7 0.4 0.3 0.6 -0.2 -0.6 -0.5 0.5 0.1 0.7 -0.5 0.3
Severe depression (siblings) 0.6 0.7 2.3 1.1 -0.6 0.3 0.3 -1.1 0.0 -0.9 0.1 1.5 0.3 0.3 -1.2 1.0 1.1
Pack years adult smoking proportion 1.9 2.8 9.2 -0.6 1.5 1.3 2.2 1.8 2.9 2.4 1.5 -0.0 3.0 0.5 1.1 0.6 0.7
Impedance of leg (right) 0.4 1.9 5.9 -1.4 -2.0 -1.1 -0.6 0.1 0.8 0.4 -1.5 -1.2 1.3 0.7 -2.3 -2.4 -1.1
Leg fat-free mass (left) 0.3 1.5 5.0 1.6 1.4 1.0 0.6 0.4 -0.6 -0.0 2.2 1.5 -0.9 -0.9 1.5 1.3 1.5
Trunk fat percentage 0.5 1.9 8.8 -1.8 -0.5 -2.6 1.0 0.2 -0.0 0.3 -1.6 -1.6 -0.1 0.2 -1.1 -3.0 -0.3
Hand grip strength (right) 1.4 3.8 10.5 2.4 0.3 1.8 -3.2 -0.7 -2.5 -1.1 1.7 2.0 -2.7 -0.8 1.5 2.8 0.9
Townsend deprivation index at recruitment 1.3 1.8 5.0 1.7 2.2 0.7 2.1 1.8 0.6 1.1 2.0 0.8 0.6 -0.5 1.3 0.6 0.7
Current tobacco smoking 0.2 0.4 2.3 -0.0 -1.0 -0.2 -0.1 -0.3 0.4 0.1 -0.1 0.7 0.8 -0.7 -0.5 -1.5 0.3
Average weekly fortified wine intake 1.1 1.3 5.1 0.4 -1.2 -0.6 -0.2 -1.4 -2.0 -1.4 -0.7 -0.1 -2.2 0.8 0.3 1.3 0.7
Maternal smoking around birth 0.7 1.1 4.0 1.3 0.0 0.9 -1.1 -1.6 -0.2 -0.4 -0.5 0.5 -0.2 1.7 -0.0 0.9 2.0
Fed-up feelings 0.9 1.7 7.9 0.4 -0.5 0.1 1.9 -1.9 -0.8 -2.0 -0.6 0.1 -1.2 -0.4 -1.0 0.9 2.8
Frequency of unenthusiasm / disinterest in last 2 weeks 1.5 1.9 9.1 1.6 -0.4 -0.3 2.5 -0.9 0.4 -0.8 0.5 1.3 0.6 1.1 -1.6 1.2 3.0
Relative age voice broke 1.3 2.0 8.6 1.6 1.6 2.5 0.0 -0.6 -0.0 -0.2 1.5 1.2 -0.2 -0.8 1.1 2.9 1.0
Taking other prescription medications 0.2 0.4 1.4 0.7 0.3 -1.2 0.3 0.1 -0.6 -0.4 -0.2 -0.1 -0.5 0.7 -0.5 0.4 1.1
Age when periods started (menarche) 0.4 0.9 2.9 1.0 1.3 0.3 -0.0 1.0 0.4 1.1 1.5 0.8 0.3 -1.7 -0.0 0.8 -0.7
Bilateral oophorectomy (both ovaries removed) 1.2 1.4 2.8 -1.4 -0.3 0.3 0.9 -1.7 0.8 0.2 -1.6 -1.7 0.7 1.6 1.0 -1.1 1.4
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.8 4.8 0.2 0.2 -0.8 -2.2 -0.9 -0.9 -0.5 -0.6 -0.0 -1.1 -1.0 -0.2 0.9 -0.3
Tinnitus: Yes, but not now, but have in the past 0.2 0.2 0.6 0.0 -0.5 -0.2 0.7 -0.5 -0.6 -0.1 -0.1 -0.0 -0.8 0.7 0.1 0.4 0.7
Qualifications: CSEs or equivalent 0.5 0.7 2.3 -1.3 -0.6 -0.7 0.9 -0.1 0.3 0.0 -0.9 -0.9 0.1 -1.5 -0.3 -1.0 -0.8
Serious illness, injury or assault to yourself 0.9 1.1 3.2 -1.6 -1.0 -0.6 0.3 1.5 0.7 0.9 -1.0 -1.2 0.8 0.1 -0.8 -1.8 -1.2
High blood pressure 0.4 1.2 2.2 -1.2 -0.0 -0.8 1.4 -1.0 1.3 0.1 -1.5 -1.4 1.0 1.2 0.8 -0.5 1.4
Hayfever, allergic rhinitis or eczema 0.1 0.3 1.2 -0.4 -0.1 0.3 -0.1 0.5 -0.7 -0.9 0.1 0.6 -0.7 -1.1 0.2 0.0 -0.3
Multivitamins +/- minerals 1.2 1.5 5.5 -1.9 0.1 -1.8 0.7 0.8 0.5 0.2 -0.7 -1.0 0.4 -1.6 1.3 -1.2 -2.4
Stomach or abdominal pain in last month 0.5 0.6 2.4 1.0 -0.3 0.2 1.1 -0.9 -0.5 -1.3 -0.2 0.5 -0.5 0.3 0.1 0.2 1.6
Supplements: Glucosamine 0.2 0.3 1.0 0.0 -0.6 -0.3 -0.7 -1.0 -0.5 -0.4 -0.1 0.4 -0.5 0.3 -0.3 0.9 -0.1
Diverticular disease/diverticulitis (self-reported) 1.0 1.2 6.4 -1.4 -0.2 1.1 1.0 -1.6 -0.1 -1.0 -2.5 -1.1 -0.7 -0.5 1.0 -0.5 0.3
Medication: Atenolol 0.4 0.5 1.6 -0.7 0.4 -0.1 0.4 1.1 1.1 0.7 -0.6 -0.6 1.2 0.4 -0.5 -0.5 -0.5
Medication: Levothyroxine sodium 0.7 1.2 3.5 1.6 1.6 -0.2 1.5 0.5 0.1 -0.1 0.9 1.2 0.2 0.2 -0.5 1.9 1.9
Sitting height 0.2 1.1 5.2 0.8 0.9 2.3 0.6 0.8 0.4 0.4 1.9 1.3 0.4 -0.8 -0.0 0.7 0.7
Chronic bronchitis/emphysema (father) 0.9 1.0 3.5 -0.8 -1.3 -0.7 -1.2 0.8 0.2 -0.0 -1.4 -0.7 0.3 0.2 -0.8 -1.8 -1.9
High blood pressure (mother) 1.3 1.8 5.2 0.8 0.8 1.6 1.5 -0.1 1.1 1.6 0.4 0.5 1.4 2.3 0.7 1.7 1.9
Body mass index (BMI) 0.2 0.8 2.4 1.0 1.5 -1.0 1.4 0.3 -0.2 0.1 0.8 0.7 -0.4 -0.1 0.9 0.9 1.6
Impedance of leg (left) 0.5 2.4 7.6 -1.6 -2.4 -1.2 -0.6 -0.5 0.3 -0.1 -2.3 -1.5 0.7 0.3 -2.5 -2.8 -1.0
Leg predicted mass (left) 0.3 1.7 5.4 1.7 1.4 1.1 0.6 0.4 -0.7 -0.0 2.3 1.6 -1.0 -0.9 1.5 1.4 1.6
Trunk fat mass 0.1 0.6 3.5 -0.5 0.2 -1.9 1.0 0.1 -0.3 0.1 -0.4 -0.5 -0.4 -0.1 -0.4 -1.4 0.6
Waist circumference 0.2 0.6 2.2 1.0 0.7 -0.6 1.5 -0.1 -0.5 -0.2 0.5 1.1 -0.6 -0.2 -0.4 0.4 1.5
Number of incorrect matches in round 0.4 0.7 2.6 0.2 -0.1 -1.6 0.1 -1.1 -0.8 -1.2 -0.2 -0.2 -1.0 -0.5 0.2 0.6 1.5
Past tobacco smoking 1.5 2.8 7.6 -2.1 0.7 -0.1 1.2 2.8 2.2 2.2 0.4 -1.3 2.3 1.1 1.2 -1.2 -2.1
Alcohol usually taken with meals 1.1 1.8 6.5 0.3 -2.1 -1.3 -2.5 -1.1 -1.1 -1.8 -1.1 0.7 -0.7 -1.0 -1.8 -0.4 -1.1
Nervous feelings 0.7 1.4 8.1 0.3 -0.9 -0.5 0.6 -1.5 -0.3 -1.9 -0.4 0.3 -0.2 0.5 -2.8 -0.3 1.8
Frequency of tenseness / restlessness in last 2 weeks 0.9 1.3 5.8 0.1 -0.9 -1.5 1.4 -1.9 0.5 -1.7 -0.8 0.1 0.5 0.8 -0.0 0.3 2.4
Hearing difficulty/problems with background noise 0.3 0.5 2.1 -0.4 -0.0 -0.0 0.7 -0.2 1.1 -0.2 -0.6 -0.5 1.3 1.5 -0.5 0.0 0.7
Hair/balding pattern: Pattern 2 0.6 0.8 2.6 1.1 0.5 0.8 0.2 -0.0 -0.5 -0.3 1.0 1.6 -0.3 -0.7 -1.2 1.6 0.3
Had menopause 2.6 3.2 12.2 2.0 -1.0 -0.6 -0.7 -1.9 -1.8 -1.4 -0.3 1.6 -1.4 2.6 -2.3 1.3 3.5
Had other major operations 1.6 1.9 5.6 1.0 -1.0 -1.9 -1.1 -0.2 -2.4 -1.8 -0.0 1.2 -2.1 -1.7 -1.4 -0.3 0.7
Forced vital capacity (FVC) 0.5 2.1 12.1 2.3 0.2 0.4 -1.5 1.1 -0.8 1.0 3.5 2.1 -0.4 -0.7 -0.2 1.1 0.6
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.1 2.9 0.9 0.7 -0.8 -1.4 -1.3 -1.3 -1.1 -0.2 0.2 -1.6 -0.9 0.1 1.7 0.9
Ever unenthusiastic/disinterested for a whole week 0.7 0.9 3.2 1.2 -0.5 -0.4 1.1 -0.8 -0.7 -0.5 0.4 0.8 -0.6 0.3 -1.3 1.4 1.8
Qualifications: None of the above 1.7 3.6 9.4 -2.4 1.4 -0.9 2.1 1.0 2.2 2.8 -0.7 -3.1 1.9 2.2 2.1 -1.1 -0.7
Financial difficulties in last 2 years 1.0 1.3 7.5 1.4 1.0 0.1 2.1 0.0 -0.1 -0.5 0.4 0.7 0.0 0.4 0.1 1.3 2.7
Mouth/teeth dental problems 0.6 1.0 3.2 -0.2 1.3 1.2 -0.7 1.3 1.0 1.3 0.7 0.1 0.9 0.4 1.8 0.5 -0.7
Heart attack 0.9 1.2 5.0 0.5 -1.2 -2.2 -0.8 -1.3 -1.1 -0.9 -0.4 1.1 -0.7 -1.0 -1.7 0.5 0.2
Allergy 0.2 0.4 1.3 0.6 0.6 0.7 0.5 0.0 0.6 1.1 0.8 -0.2 0.5 0.8 0.3 0.8 0.3
Pain all over the body in last month 1.7 1.8 6.5 -0.2 1.5 0.3 0.6 2.5 1.5 1.8 1.7 -0.5 1.5 -0.9 0.7 -0.1 -2.0
Diabetes (self-reported) 1.5 2.3 6.6 1.9 1.8 0.3 2.3 -0.1 -0.4 -0.5 1.6 2.1 -0.5 -1.0 0.1 2.6 2.1
Hayfever/allergic rhinitis (self-reported) 0.4 0.5 1.8 -1.0 -0.7 -1.3 -0.3 0.9 -0.2 0.1 0.3 -0.3 0.0 0.3 -1.2 -1.2 -0.2
Medication: Ramipril 0.4 0.5 3.2 0.3 0.6 -0.3 -0.6 -0.9 -0.5 -0.4 -0.7 -0.0 -0.5 0.6 0.1 1.0 1.8
Medication: Simvastatin 1.7 2.5 5.6 0.6 2.2 1.7 2.4 1.3 1.8 1.3 1.3 0.5 1.5 1.7 1.1 1.6 2.0
Fluid intelligence score 2.1 4.3 11.4 2.9 3.2 1.3 -0.6 1.0 -0.3 -0.7 2.5 2.7 -0.6 -3.4 1.6 3.0 -1.0
Illnesses of siblings 0.4 0.5 2.3 -0.1 0.6 -0.5 0.7 1.1 -0.0 0.0 1.5 0.5 0.0 -1.2 0.9 -0.4 -0.6
Neuroticism score 1.2 2.5 13.5 0.5 -0.8 -0.6 0.8 -2.4 -1.0 -2.5 -1.0 0.0 -1.1 1.1 -1.7 1.0 3.7
Weight 0.2 0.9 3.5 1.2 1.2 -0.0 0.8 -0.0 -0.6 -0.2 1.2 1.1 -0.8 -0.5 0.8 1.0 1.9
Impedance of arm (right) 1.7 7.8 28.4 -4.5 -2.7 -1.4 0.2 0.5 1.2 1.1 -3.8 -3.4 1.7 0.5 -2.7 -5.3 -3.5
Arm fat percentage (right) 0.2 0.7 3.3 -0.8 0.6 -1.8 1.4 0.8 0.2 0.4 -0.7 -0.6 0.0 0.3 -0.5 -1.1 0.4
Trunk fat-free mass 0.9 5.4 15.5 3.5 1.7 2.1 -0.5 -0.3 -1.3 -0.7 3.5 3.1 -1.6 -1.1 1.5 3.9 3.2
Hip circumference 0.1 0.3 1.9 0.7 0.6 0.3 0.4 0.0 -0.3 -0.2 0.7 0.6 -0.6 -0.3 0.3 0.3 1.4
Time employed in main current job 0.5 0.5 3.0 0.4 0.0 -1.0 0.1 -0.8 -0.8 -0.3 -0.4 0.8 -0.8 0.1 -0.1 1.7 0.8
Alcohol intake versus 10 years previously 2.2 3.2 8.6 -2.8 -0.2 -1.9 -0.0 0.4 2.0 1.4 -1.3 -2.4 2.2 -1.0 0.3 -2.9 -2.4
Father’s age at death 1.2 1.6 6.9 1.9 0.3 0.1 -1.3 -0.2 -2.5 -1.0 1.0 0.8 -2.6 0.4 -0.3 0.9 0.3
Worrier / anxious feelings 0.8 1.5 4.6 0.7 -1.0 -1.2 0.2 -2.0 -0.9 -2.1 -0.6 1.0 -0.7 -0.0 -2.1 0.2 1.7
Frequency of tiredness / lethargy in last 2 weeks 2.8 4.5 12.5 3.5 1.5 0.2 2.7 1.8 -0.3 -1.2 3.3 2.8 -0.3 -1.0 -0.4 3.0 2.6
Falls in the last year 0.4 0.5 2.6 -0.2 0.8 0.0 1.6 0.3 0.9 0.2 -0.4 -0.3 0.9 0.9 0.6 -0.2 0.6
Hair/balding pattern: Pattern 3 0.3 0.4 1.2 -0.2 -0.2 -0.9 0.2 -1.1 -0.1 -0.9 -1.0 -0.5 -0.2 -0.8 -0.5 -0.3 0.2
Number of live births 0.3 0.5 1.3 -0.6 0.4 0.8 -0.7 0.5 0.7 1.0 0.1 -1.0 0.7 1.1 -0.0 -0.5 0.5
Forced expiratory volume in 1-second (FEV1) 0.8 2.7 11.6 2.7 -0.1 -0.2 -1.4 0.7 -1.6 0.3 3.4 2.7 -1.2 -1.2 -0.9 1.3 1.0
Pulse rate 0.2 0.3 1.1 -0.3 1.1 0.5 0.7 -0.3 0.6 0.6 -0.0 -0.3 0.5 0.5 0.8 0.1 0.5
Happiness 0.4 0.4 3.2 -0.1 0.2 0.1 1.8 -0.1 0.8 0.0 0.3 0.1 0.9 -0.6 -0.3 0.6 0.6
Noisy workplace 0.4 0.4 1.4 -0.4 -0.5 -0.4 1.2 1.2 0.8 0.7 0.4 0.1 0.9 0.3 -0.3 -0.5 0.4
Qualifications: A levels/AS levels or equivalent 0.5 1.1 3.2 1.4 1.4 1.5 -1.3 0.8 0.1 0.1 1.8 1.4 0.4 -1.0 0.3 1.1 -0.4
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.5 2.1 1.0 -0.6 0.1 -0.3 0.1 -0.7 -0.8 0.3 1.4 -0.3 -1.2 -0.8 0.7 -0.6
Mouth/teeth dental problems: Dentures 0.6 0.9 6.6 -0.1 -1.6 -0.2 0.7 -1.1 0.4 -0.2 -0.9 -0.2 0.5 0.1 -2.6 -0.8 0.7
Asthma 0.2 0.3 0.9 0.8 -0.1 0.1 -0.4 -0.5 0.6 -0.6 -0.4 0.6 0.8 -0.2 -1.0 -0.5 0.1
Medication: Ibuprofen (e.g. Nurofen) 0.2 0.3 0.9 0.1 -0.6 -0.9 0.8 -0.0 -0.1 -0.2 0.8 0.6 0.2 -0.3 -0.4 -0.7 -0.1
Medication: Cholesterol lowering 0.5 0.8 3.5 0.9 1.6 -0.1 1.4 0.1 0.1 -0.3 0.3 0.5 -0.1 0.3 0.4 1.9 1.2
Depression (self-reported) 1.2 1.4 6.3 1.2 -0.3 -1.3 1.1 -0.9 -1.1 -0.7 0.1 0.5 -1.0 1.0 -2.0 0.0 2.5
Medication: Lansoprazole 0.7 0.7 2.8 -0.7 -0.3 -0.3 -0.6 0.3 0.6 1.4 -0.2 -1.2 0.7 1.1 -0.0 -1.7 -1.0
Prospective memory result 0.7 0.9 3.8 -1.3 -1.1 -0.3 -0.1 0.9 0.2 0.5 -0.7 -1.1 0.5 -0.1 -0.9 -1.9 -1.3
Lung cancer (father) 0.8 0.9 2.5 1.6 -0.6 -0.6 -1.3 -0.2 -1.3 -0.9 0.8 0.8 -1.0 0.9 -0.9 0.1 1.2
Illnesses of mother 0.9 1.1 3.8 0.0 -0.4 0.2 0.6 0.9 0.2 0.3 1.2 0.9 0.3 -1.8 -1.2 -1.7 -1.9
Forced expiratory volume in 1-second (FEV1), Best measure 0.7 2.1 6.4 2.1 -1.1 -0.4 -1.2 0.3 -1.5 -0.3 2.5 2.5 -1.0 -1.4 -1.8 1.1 0.6
Pulse wave Arterial Stiffness index 0.3 0.3 2.2 0.7 1.5 0.4 -0.1 0.2 -0.3 -0.1 -0.4 0.2 -0.5 0.6 0.4 0.9 0.3
Impedance of arm (left) 2.1 9.6 38.1 -5.1 -2.9 -2.0 0.1 0.8 1.0 1.1 -3.9 -4.0 1.5 0.4 -2.7 -6.2 -3.9
Arm fat mass (right) 0.1 0.5 2.0 0.5 1.1 -1.1 1.2 0.5 -0.2 0.2 0.5 0.4 -0.5 0.2 0.2 0.3 1.4
Trunk predicted mass 1.0 5.6 15.8 3.5 1.8 2.0 -0.5 -0.2 -1.3 -0.8 3.6 3.2 -1.6 -1.2 1.5 4.0 3.2
Standing height 0.1 0.8 5.3 0.6 -0.0 2.3 -0.6 -0.5 -0.5 -0.2 1.1 1.0 -0.6 -0.8 0.2 0.4 1.0
Length of working week for main job 0.5 0.6 4.4 0.2 0.6 0.2 -0.0 0.3 -0.8 -0.9 -0.2 0.4 -1.0 -2.1 0.5 -0.2 -0.1
Exposure to tobacco smoke at home 0.6 0.6 1.5 0.8 0.4 0.8 0.9 -0.8 0.1 -0.7 0.0 1.2 0.2 -1.0 -0.1 1.2 1.1
Breastfed as a baby 0.2 0.3 0.9 0.8 0.5 0.2 0.2 0.3 -0.3 0.5 0.7 0.9 -0.1 -0.6 0.1 1.0 -0.0
Tense / ‘highly strung’ 0.6 1.1 3.9 0.2 -1.1 -1.3 0.3 -1.4 0.2 -2.0 -0.6 0.6 0.4 -0.2 -1.3 0.1 1.8
Seen doctor (GP) for nerves, anxiety, tension or depression 2.8 4.2 21.4 2.8 0.5 0.0 1.6 -2.0 -0.4 -1.1 1.0 1.9 -0.1 2.9 -1.6 2.6 4.6
Hair/balding pattern: Pattern 4 0.3 0.8 2.7 -0.7 -0.8 0.0 -0.7 0.7 0.6 0.6 -1.3 -0.7 0.8 0.7 -0.2 -1.6 -1.3
Birth weight of first child 0.4 0.6 4.9 -0.1 -0.3 -0.7 -0.2 -2.2 -0.3 -0.7 -1.0 -0.3 -0.5 0.4 0.6 0.7 0.7
Peak expiratory flow (PEF) 0.2 0.5 1.4 1.0 -0.8 0.4 -1.2 -0.2 -0.7 0.1 1.0 1.1 -0.4 0.0 -0.7 0.1 1.1
Pulse wave reflection index 0.7 0.9 3.8 1.2 2.0 0.4 0.2 1.3 0.4 0.5 1.0 0.4 0.3 0.3 0.3 1.7 0.4
Ever highly irritable/argumentative for 2 days 0.6 0.7 2.6 0.2 0.3 -0.5 1.4 -0.8 -0.8 -0.9 0.2 0.1 -1.1 -0.3 0.6 0.9 1.6
Loud music exposure frequency 0.7 0.7 2.8 1.2 1.1 0.0 0.0 0.6 -0.4 -0.1 1.0 1.7 -0.2 -1.3 -0.3 1.1 -0.5
Qualifications: O levels/GCSEs or equivalent 0.2 0.4 1.2 1.1 0.7 0.9 -0.3 0.7 -0.5 -0.0 1.0 0.7 -0.5 0.4 0.3 0.3 -0.0
Mouth/teeth dental problems: Bleeding gums 0.6 0.8 3.1 0.8 -0.5 -0.8 0.6 -0.5 -1.8 -1.2 0.0 0.4 -1.8 -0.9 -0.6 0.1 0.6
Blood clot in the leg (DVT) 1.0 1.3 3.1 -1.7 -0.6 -1.7 -0.4 -0.8 -0.2 0.1 -1.6 -1.8 -0.4 1.5 0.0 -1.5 -0.8
Medication: Paracetamol 0.2 0.4 1.1 0.1 1.1 -0.4 0.3 0.9 0.1 0.8 0.8 0.0 -0.0 0.6 1.0 0.7 0.1
Headache pain in last month 0.2 0.4 1.3 -0.6 -1.1 -0.2 -0.1 0.4 0.7 0.7 -0.4 -0.0 1.0 0.3 -0.1 -0.9 0.4
Medication for cholesterol, blood pressure or diabetes 0.1 0.2 0.7 0.3 -0.9 0.8 -0.5 0.2 -0.1 0.2 0.6 0.8 0.1 0.3 -0.3 0.2 -0.2
Glaucoma (self-reported) 0.6 0.7 2.6 -0.3 0.9 0.2 0.3 0.6 1.4 1.3 0.1 -0.4 1.6 1.4 0.5 0.7 -0.2
Gout (self-reported) 0.5 0.7 2.2 1.3 -0.2 -0.8 -0.9 -0.1 -0.8 -0.7 0.7 1.5 -0.6 -1.4 0.1 0.3 -0.4
Hypothyroidism/myxoedema (self-reported) 0.5 1.0 3.1 1.7 1.2 -0.2 1.5 0.5 -0.2 -0.4 1.1 0.8 -0.2 0.5 -0.6 1.2 1.8
Medication: Amlodipine 0.4 0.6 1.6 -0.1 1.1 -0.3 0.8 0.6 1.1 1.3 0.8 0.1 1.2 0.8 -0.3 -0.1 -0.1
Medication: Ventolin 100micrograms inhaler 0.7 0.9 3.7 -1.1 -0.5 1.1 0.0 -0.8 1.0 0.8 -0.4 -1.0 1.0 0.6 1.9 -0.8 -0.2
Birth weight 0.2 0.5 1.8 0.9 0.4 0.9 0.1 1.0 -0.4 -0.2 1.0 1.1 -0.3 0.1 -0.0 1.3 -0.0
Chronic bronchitis/emphysema (mother) 0.2 0.2 1.1 0.3 -0.8 0.3 0.2 0.2 0.6 -0.2 0.2 -0.2 0.7 0.4 -0.3 -0.3 1.1
High blood pressure (siblings) 0.6 0.8 1.8 1.1 -0.3 1.1 -0.5 -1.4 -0.2 -0.3 -1.2 0.2 -0.4 1.4 -0.5 0.9 1.3
Forced vital capacity (FVC), Best measure 0.4 1.5 8.6 1.6 -0.5 0.7 -1.0 1.2 -0.3 0.9 2.9 1.8 0.1 -0.6 -1.0 0.7 0.1
Body fat percentage 0.3 1.3 7.2 -1.1 -0.3 -2.7 0.7 -0.1 -0.4 -0.0 -1.4 -1.2 -0.5 0.3 -1.0 -2.1 0.2
Leg fat percentage (right) 0.2 0.6 4.6 0.5 0.4 -2.2 0.5 0.0 -0.3 -0.1 -0.2 0.0 -0.3 0.7 -0.6 -0.4 1.3
Arm fat-free mass (right) 0.9 4.7 11.4 3.4 1.5 1.3 -0.2 -0.6 -1.6 -1.1 3.1 2.6 -2.1 -1.0 1.5 3.3 3.3
Exposure to tobacco smoke outside home 0.7 0.9 4.4 -0.2 -1.2 -1.3 -0.3 -2.1 0.2 -0.9 -1.1 0.2 0.3 0.6 -0.8 0.2 1.3
Comparative body size at age 10 0.4 1.1 3.3 1.8 1.5 -0.7 0.0 1.8 0.1 0.6 1.8 0.8 -0.0 0.6 0.8 1.2 -0.2
Number of full brothers 1.5 1.9 6.8 -0.7 1.0 0.8 0.7 1.9 1.8 2.6 0.3 -1.2 1.8 -0.4 1.0 -0.4 -2.0
Worry too long after embarrassment 0.2 0.4 1.8 -0.0 -0.1 -1.1 -0.8 -0.3 -0.5 -0.5 0.4 -0.4 -0.6 0.6 -0.2 0.1 1.4
Seen a psychiatrist for nerves, anxiety, tension or depression 2.3 3.0 14.1 2.5 -0.4 0.0 0.6 -1.6 -0.6 -0.3 1.0 1.2 -0.2 3.3 -2.1 0.8 3.8
Wheeze or whistling in the chest in last year 0.6 1.1 4.3 0.6 -2.1 -0.3 0.4 -0.5 0.6 -0.8 -0.8 0.7 1.1 -0.1 -2.1 -1.1 1.0
Number of children fathered 0.5 0.5 1.5 0.6 1.2 -0.2 0.8 0.0 0.6 0.4 0.7 0.6 0.5 1.2 0.4 1.1 0.9
Reason for reducing amount of alcohol drunk: Health precaution 2.2 2.5 7.0 0.8 -1.2 -1.0 -1.0 -2.2 -2.6 -2.6 -0.7 0.9 -2.7 -1.0 -1.4 0.7 1.0
Age at first live birth 0.6 1.1 4.5 -0.6 -0.8 0.7 -1.3 -0.4 -0.6 -1.5 -0.9 0.1 -0.8 -2.1 0.5 -0.3 -1.8
Pulse wave peak to peak time 0.3 0.3 2.2 -0.7 -1.5 -0.1 0.1 -0.2 0.5 0.2 0.5 -0.1 0.6 -0.6 -0.3 -0.8 -0.3
Health satisfaction 0.8 1.1 4.6 -0.7 0.3 0.9 2.1 0.6 1.2 0.7 0.2 -1.2 1.1 1.0 0.3 0.1 1.7
Shortness of breath walking on level ground 0.5 0.6 2.4 -1.0 -0.1 0.9 1.6 -0.8 0.5 -0.3 -1.2 -1.0 0.2 -0.2 -0.8 -0.5 0.6
Qualifications: College or University degree 0.8 2.4 9.9 0.7 -0.6 2.1 -3.2 -1.7 -1.5 -2.0 -1.2 1.0 -1.6 -1.0 -0.3 1.4 0.8
Eye problems/disorders: None of the above 0.5 0.6 2.6 1.0 0.2 1.6 0.6 -0.2 -0.6 -0.3 0.6 0.9 -0.6 -0.6 -0.1 1.3 0.9
Mouth/teeth dental problems: Loose teeth 0.8 0.9 4.2 0.8 -2.0 -0.2 -0.9 -1.1 -0.8 -0.5 0.3 0.7 -0.4 0.3 -1.8 -0.3 0.7
Emphysema/chronic bronchitis 0.8 0.9 3.6 -1.1 -0.4 -0.6 0.3 -1.0 0.4 -0.1 -1.6 -1.1 0.4 1.9 0.6 -0.9 1.0
Medication for pain relief, constipation, heartburn 0.4 0.6 1.3 -0.6 -1.0 -0.4 -1.1 -0.9 -0.6 -0.6 -0.7 -0.6 -0.7 -1.0 0.0 -1.0 -1.2
Neck or shoulder pain in last month 0.6 0.9 2.7 -0.2 1.0 -0.0 1.4 1.6 1.1 1.1 0.7 -0.1 1.3 1.3 0.8 0.6 -0.1
Medication: Blood pressure 0.1 0.1 0.7 0.2 0.7 -0.9 -0.0 -0.2 -0.1 -0.3 -0.5 0.2 -0.2 -0.4 0.3 0.1 0.2
Angina (self-reported) 0.5 0.6 1.9 -0.5 0.9 0.2 0.5 1.2 0.9 1.4 0.4 -0.7 0.9 0.7 0.8 0.5 -0.6
Migraine (self-reported) 0.3 0.4 1.3 -0.4 -0.5 1.2 0.6 -0.5 1.0 0.0 -1.0 0.0 1.0 0.4 -0.3 -0.1 0.7
Medication: Ibuprofen 0.2 0.3 1.3 0.4 -0.3 -0.1 1.1 -0.1 -0.1 -0.1 1.0 0.7 -0.0 0.1 -0.1 -0.4 0.6
Medication: Allopurinol 0.9 1.2 4.1 1.6 0.1 -0.9 -0.8 0.1 -1.2 -0.9 1.1 2.0 -1.0 -1.8 0.3 0.6 -0.7
Medication: Omeprazole 0.7 0.9 2.3 -1.3 -0.8 0.3 -1.0 -0.9 -0.5 -0.2 -1.5 -1.5 -0.6 1.1 0.5 -1.1 0.9
Medication: Seretide 50 evohaler 0.5 0.5 2.2 -0.1 0.8 1.2 1.5 -0.5 0.7 -0.1 -0.5 0.4 0.6 -0.6 -0.0 0.8 0.9
Mean time to correctly identify matches 0.4 0.7 2.0 0.5 1.4 0.1 0.9 1.4 0.9 1.2 1.0 0.7 1.0 0.5 -0.2 0.6 -0.1
Heart disease (mother) 0.9 1.0 4.6 -0.8 -0.5 -0.5 -1.6 -0.9 -1.0 -0.7 -2.1 -1.3 -1.1 0.6 -0.4 0.1 0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.5 0.5 2.3 0.2 0.4 1.2 0.7 -0.1 0.7 -0.5 0.3 -0.5 0.6 -0.1 1.5 0.9 1.0
Whole body fat mass 0.1 0.4 2.6 0.1 0.6 -1.6 0.9 0.1 -0.4 0.1 0.0 -0.0 -0.6 -0.1 -0.1 -0.5 1.0
Leg fat mass (right) 0.2 0.6 3.0 1.1 0.9 -1.1 1.0 0.1 -0.3 0.0 0.8 0.6 -0.5 0.4 0.3 0.4 1.7
Arm predicted mass (right) 1.0 5.0 12.2 3.5 1.7 1.3 -0.1 -0.6 -1.5 -1.0 3.4 2.8 -1.9 -0.8 1.6 3.5 3.5
Pulse rate, automated reading 0.4 1.4 5.1 1.6 1.4 -0.3 1.5 -1.1 0.1 -0.4 0.7 1.4 -0.1 0.9 0.5 1.9 2.2
Alcohol intake frequency. 2.6 6.0 14.1 -3.4 0.9 0.5 3.0 2.4 3.3 3.8 -0.1 -2.9 3.3 1.6 1.2 -2.3 -1.5
Comparative height size at age 10 0.1 0.4 2.4 -0.8 -0.3 1.6 0.4 -0.6 0.2 0.6 -0.2 -0.5 -0.2 0.1 1.2 -0.1 0.2
Number of full sisters 0.2 0.2 0.5 0.0 0.2 0.7 -0.6 0.7 -0.4 0.7 0.0 -0.5 -0.6 0.1 0.4 0.0 -0.6
Suffer from ‘nerves’ 0.9 1.4 6.2 0.1 -0.3 0.6 1.8 -0.7 1.0 -0.5 -0.2 -0.1 1.1 2.5 -1.0 0.8 2.2
Overall health rating 1.1 2.3 14.2 0.6 1.7 0.4 3.8 1.1 2.0 1.2 1.0 0.2 2.0 0.7 0.3 0.9 1.4
Chest pain or discomfort 1.2 1.7 5.1 -1.6 -0.5 0.8 1.1 -0.5 1.9 1.0 -1.4 -2.2 2.1 1.2 0.6 -1.0 0.6
Had major operations 0.4 0.5 1.9 1.0 -0.3 -1.2 0.1 0.0 -0.4 -0.3 0.3 1.0 -0.2 0.2 -1.4 -0.5 0.5
Age at last live birth 0.4 0.6 2.9 -0.7 -0.7 0.2 -0.8 -0.6 -0.5 -1.0 -0.6 -0.3 -0.5 -1.7 0.5 0.1 -1.1
Family relationship satisfaction 0.6 0.7 4.1 -0.1 1.0 -1.0 2.0 0.5 0.7 0.7 0.2 -0.3 0.9 0.8 0.2 0.5 0.8
Leg pain on walking 0.3 0.4 1.0 0.2 -0.7 0.1 1.0 -0.3 -0.6 -0.7 -0.7 0.0 -0.7 -0.7 -0.7 -0.5 0.7
Qualifications: NVQ or HND or HNC or equivalent 1.3 1.6 9.4 0.5 0.4 -1.6 0.8 0.7 -1.3 -1.4 0.6 1.2 -1.6 -3.1 0.2 0.8 -0.2
Commuting to job workplace: Car/motor vehicle 0.3 0.4 2.2 -0.2 -1.2 -0.5 -0.6 -0.8 -0.2 -0.3 -0.4 0.2 -0.0 0.2 -1.5 -0.0 -0.3
Illness, injury, bereavement, stress in last 2 years 0.3 0.4 1.9 0.3 0.5 0.6 0.4 0.9 0.8 0.6 1.4 0.5 0.8 0.4 -0.2 -0.1 -0.2
Medication: Aspirin 1.5 2.0 5.9 2.4 0.8 1.3 1.1 0.8 -0.2 -0.4 1.7 2.1 0.0 0.1 -1.3 2.3 1.9
Supplements: Vitamin C 2.4 2.9 7.1 1.7 -1.8 -1.2 0.0 -2.0 -1.9 -2.7 0.6 2.1 -1.6 -1.5 -2.2 0.9 1.5
Knee pain experienced in last month 1.5 2.4 7.0 -0.6 -2.5 -2.6 -0.7 -2.2 -1.1 -1.5 -1.6 0.2 -1.0 -0.3 -2.0 -1.7 1.0
Hypertension (Self-reported) 0.3 0.8 1.9 -0.8 0.1 -1.1 1.4 -0.8 1.2 -0.0 -1.2 -1.0 0.9 0.6 0.2 -0.4 1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.6 1.9 4.5 -1.4 1.3 1.2 0.6 -0.5 1.9 1.9 -0.6 -1.5 1.7 2.1 1.8 0.5 0.5
Illnesses of father: Heart disease 0.5 0.8 2.5 0.7 0.9 0.1 0.4 -0.5 0.2 0.7 0.3 -0.0 -0.1 1.6 1.5 1.1 1.5
Illnesses of siblings: Diabetes 0.5 0.6 1.8 0.8 1.0 0.5 1.3 0.6 0.2 1.0 1.2 0.6 0.0 0.5 -0.1 1.3 0.3
Smoking status: Previous 1.9 2.8 7.8 2.3 -0.4 0.6 -0.8 -2.8 -1.8 -2.2 -0.6 1.2 -2.1 -1.2 -1.1 1.8 2.2
Forced expiratory volume in 1-second (FEV1), predicted 0.5 1.0 2.1 -1.3 -0.3 1.1 0.4 1.0 1.2 1.5 1.0 -0.9 1.2 -1.0 0.9 -0.6 -0.8
Whole body fat-free mass 0.7 3.9 9.5 2.8 1.7 1.7 0.1 -0.1 -1.1 -0.6 3.1 2.5 -1.5 -1.1 1.6 3.1 2.7
Leg fat-free mass (right) 0.3 1.6 3.5 1.4 1.3 1.2 0.7 0.1 -0.9 -0.3 1.9 1.3 -1.3 -1.1 1.7 1.4 1.6
Arm fat percentage (left) 0.2 1.0 4.9 -1.1 0.5 -2.2 1.2 0.8 0.1 0.5 -0.9 -1.0 0.0 0.2 -0.6 -1.7 0.1
Average weekly red wine intake 0.4 0.5 2.0 1.1 -0.4 0.2 -1.4 -0.3 -0.6 -0.7 0.6 1.3 -0.3 0.5 -0.2 0.8 0.3
Handedness (chirality/laterality): Left-handed 0.4 0.4 1.5 0.6 -0.6 -0.7 -0.7 -0.6 -0.6 -0.7 -0.1 0.6 -0.1 -0.6 -1.2 -1.1 0.1
Mood swings 0.8 1.5 7.5 0.9 0.7 0.6 2.0 -1.1 -0.0 -1.0 0.1 0.8 -0.3 -0.0 0.3 2.2 2.7
Loneliness, isolation 0.9 1.2 4.3 -0.5 -0.2 -0.5 0.6 -1.9 -0.1 -0.9 -1.3 -1.0 -0.2 2.0 -0.4 -0.4 2.1
Long-standing illness, disability or infirmity 0.3 0.5 1.6 -0.1 0.3 -0.0 1.0 -0.2 0.6 -0.0 -1.2 -0.9 0.3 0.7 0.6 -0.4 1.3
Ever had bowel cancer screening 0.3 0.3 1.2 -0.4 0.5 0.4 0.1 -0.0 0.1 0.2 -1.1 -1.0 -0.1 1.1 0.3 -0.2 0.3
Diabetes diagnosed by doctor 0.8 1.2 4.1 1.4 1.3 -0.3 2.0 -0.2 -0.3 -0.4 0.9 1.3 -0.4 -0.3 -0.1 2.0 1.6
Ever had stillbirth, spontaneous miscarriage or termination 0.5 0.5 1.6 0.5 -0.4 -0.1 -1.3 0.6 -0.6 -0.3 0.8 0.9 -0.3 -1.2 -0.7 -0.4 -1.2
Friendships satisfaction 1.1 1.3 4.8 -0.0 1.6 0.6 2.2 0.8 1.2 1.1 0.2 -0.1 1.3 1.3 0.5 1.4 1.3
Qualifications: nursing, teaching 0.9 1.4 9.4 1.2 -1.0 0.1 -3.1 -1.1 -1.2 -0.7 0.3 1.3 -0.9 0.1 -1.0 0.4 0.2
Commuting to job workplace: Walk 1.1 1.1 3.2 -0.1 1.8 0.7 0.6 1.3 1.3 1.3 1.4 -0.1 1.2 0.2 1.7 -0.4 -0.5
Eye problems/disorders: Cataract 2.7 3.2 8.3 -0.4 -1.6 -2.8 -1.7 -2.9 -2.0 -2.5 -1.8 -0.8 -2.2 -0.0 -1.6 -1.0 0.0
Mouth/teeth dental problems: Mouth ulcers 0.3 0.4 2.5 0.4 1.1 0.3 1.6 0.9 0.1 -0.0 0.6 0.2 0.0 0.2 0.5 0.2 0.5
Medication for cholesterol 1.5 2.3 7.1 1.3 -1.1 -1.1 -2.7 0.3 -1.8 -1.0 0.8 1.0 -1.4 -2.2 -1.8 -1.1 -1.9
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.1 1.2 3.5 -0.4 -1.0 -0.6 0.9 -1.6 -1.1 -1.0 -1.9 -0.7 -1.3 1.3 -0.7 -0.5 1.5
Back pain experienced in last month 1.1 1.6 10.5 -0.6 -1.2 0.0 0.3 -1.6 0.8 0.5 -1.0 -0.8 0.8 3.2 -0.3 -0.3 1.9
Mineral and other dietary supplements 0.2 0.3 0.7 -0.6 0.1 0.7 0.3 -0.0 -0.2 0.4 -0.8 -0.6 -0.5 -0.6 0.8 -0.1 -0.1
Breast cancer (self-reported) 0.5 0.7 2.2 -0.7 -0.3 0.1 0.3 1.4 0.4 0.8 -0.6 -1.1 0.4 0.9 -0.1 -1.5 -1.0
Asthma (self-reported) 0.2 0.4 1.3 0.9 -0.2 0.1 -0.3 -0.6 0.7 -0.7 -0.4 0.7 0.8 -0.1 -1.1 -0.3 0.4
Osteoporosis (self-reported) 0.5 0.6 1.7 -0.3 -0.2 -1.1 0.4 0.4 -0.0 1.2 -0.1 -1.0 0.1 1.3 -1.0 -0.7 -1.2
Osteoarthritis (self-reported) 0.8 1.0 4.0 -0.3 -0.8 -2.0 -1.0 -0.5 -1.6 -0.3 -0.5 -0.5 -1.5 1.1 -0.8 -0.9 0.5
Medication: Aspirin 1.5 1.9 6.0 2.5 0.1 1.1 0.4 -0.1 -0.9 -0.9 1.1 2.2 -0.6 0.2 -1.8 2.0 2.0
Medication: Gliclazide 0.5 0.6 2.7 0.1 0.7 1.5 1.6 -0.7 0.8 -0.1 0.2 0.3 0.7 0.0 0.7 0.9 0.4
Illnesses of father: None of the above (group 1) 0.4 0.5 1.5 0.6 0.2 -0.9 -0.5 0.3 -0.2 -0.3 1.1 1.0 0.1 -1.2 -0.6 0.2 -0.8
Smoking status: Current 0.3 0.6 3.0 -0.3 -1.4 -0.7 -0.4 -0.6 -0.1 -0.3 -0.5 0.5 0.2 -0.8 -0.6 -1.7 0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.9 2.0 3.9 1.9 -1.3 -1.3 -1.5 -1.0 -1.7 -1.2 1.0 1.4 -1.5 -0.6 -1.5 2.0 1.2
Whole body water mass 0.7 4.0 10.1 3.0 1.8 1.7 0.1 -0.0 -1.1 -0.5 3.2 2.6 -1.4 -1.0 1.6 3.1 2.7
Leg predicted mass (right) 0.3 1.7 3.8 1.5 1.4 1.3 0.7 0.0 -0.8 -0.2 2.0 1.4 -1.2 -1.0 1.8 1.5 1.7
Arm fat mass (left) 0.1 0.5 1.8 0.3 1.2 -1.1 1.3 0.5 -0.2 0.2 0.5 0.2 -0.4 -0.1 0.3 -0.0 1.3
Number of self-reported non-cancer illnesses 0.2 0.4 2.3 0.3 0.0 -0.4 0.8 -0.3 -0.1 -0.1 -0.7 -0.3 -0.2 1.1 -0.4 0.1 1.5
Average weekly champagne plus white wine intake 0.4 0.6 2.2 0.6 0.8 1.5 0.3 -0.6 0.2 -0.5 0.0 0.1 -0.1 0.9 0.1 1.4 1.1
Miserableness 1.5 2.6 13.0 1.4 -0.3 -0.3 1.3 -2.2 -1.2 -2.1 -0.2 1.6 -1.2 0.1 -1.2 1.9 3.6
Guilty feelings 0.7 1.1 4.8 0.4 0.2 0.2 0.8 -2.0 -0.3 -1.5 -1.2 -0.3 -0.6 0.9 -0.1 0.9 2.2
Wears glasses or contact lenses 1.0 1.2 3.5 1.9 1.1 1.0 0.2 -0.6 -0.8 -0.5 0.1 1.2 -1.0 1.2 -0.9 1.9 1.0
Ever taken oral contraceptive pill 2.5 2.8 6.5 0.4 2.4 1.1 2.0 2.2 1.8 2.5 2.4 0.4 1.9 1.0 0.9 1.3 -0.1
Hearing aid user 1.3 1.4 4.5 -1.0 1.0 1.7 1.9 0.7 2.1 0.9 -0.5 0.1 1.8 -0.3 0.6 -0.5 -1.1
Mother’s age at death 0.5 0.6 3.4 -0.7 -0.8 1.1 -0.1 -0.1 0.2 -0.0 -1.2 -0.8 0.2 1.8 -0.5 -0.7 -0.4
Financial situation satisfaction 0.9 1.1 2.7 -1.0 -1.6 -1.3 0.8 -0.4 0.6 0.7 -1.1 -1.0 1.2 0.7 -1.6 -1.3 0.0
Tinnitus: Yes, now most or all of the time 1.4 1.6 5.8 1.5 0.9 1.5 1.4 1.1 -0.1 -0.1 1.9 1.7 -0.2 -0.2 0.6 2.4 1.1
Commuting to job workplace: Public transport 0.3 0.4 2.1 0.3 -0.1 0.1 -0.4 0.4 -0.4 -0.4 -0.6 -0.2 -0.3 0.1 -0.6 -1.2 -1.4
Eye problems/disorders: Glaucoma 1.1 1.3 4.5 -1.1 0.9 0.5 0.4 1.3 2.0 1.4 -0.3 -0.9 2.1 1.3 0.7 0.1 -0.5
Medication: Blood pressure 0.8 1.6 4.1 -1.2 1.5 0.5 2.0 0.3 1.8 1.0 -0.5 -1.2 1.4 1.3 2.0 0.8 0.5
Pain type(s) experienced in last month: Hip pain 1.4 1.7 7.7 1.2 -0.8 -1.1 0.6 -2.2 -0.6 -1.4 -0.4 0.6 -0.5 1.8 -0.7 1.0 2.8
Supplements: Fish oil (including cod liver oil) 0.3 0.4 1.8 0.8 0.3 -0.5 0.2 -0.4 -0.0 -0.6 0.9 0.5 0.1 0.8 -0.2 0.8 1.4
High cholesterol (Self-reported) 0.9 1.6 5.2 1.4 1.1 0.7 2.1 0.3 0.8 0.1 1.2 1.2 0.7 1.0 -0.5 2.3 2.0
Medication: Bendroflumethiazide 0.3 0.5 1.9 -0.7 0.4 0.9 0.6 -1.1 0.8 0.0 -1.4 -0.3 0.6 0.4 0.6 -0.1 -0.2
Medication: Paracetamol 0.4 0.6 1.6 0.9 0.9 0.6 0.7 1.1 -0.0 0.3 1.3 0.7 -0.1 0.6 0.8 1.1 0.8
Medication: Lisinopril 1.6 2.1 5.3 -2.0 0.8 1.3 1.6 1.3 2.3 0.5 -1.4 -2.0 1.9 0.6 1.9 -0.1 -0.6
Medication: Atorvastatin 1.4 1.7 6.1 2.1 0.5 0.6 0.8 0.3 -0.8 -1.0 1.6 2.5 -0.7 -1.2 -1.1 2.1 0.8
Illnesses of father: High blood pressure 0.8 1.0 5.2 0.3 0.5 2.0 1.3 -0.1 0.3 -0.1 0.3 0.1 0.2 1.2 0.5 0.8 2.3
Alcohol drinker status: Never 0.9 1.1 2.8 0.3 1.3 1.1 1.7 1.0 1.1 0.7 0.8 1.0 1.3 0.8 -0.3 1.0 1.4
Ever smoked 1.6 2.7 5.6 2.2 -0.9 0.1 -1.3 -1.7 -2.2 -2.4 0.5 1.9 -2.1 -2.2 -1.8 0.7 0.9
Basal metabolic rate 0.6 3.2 7.9 2.6 1.6 1.3 0.3 0.0 -1.0 -0.5 2.8 2.4 -1.4 -1.0 1.4 2.6 2.6
Leg fat percentage (left) 0.2 0.8 5.2 0.4 0.1 -2.3 0.3 -0.5 -0.8 -0.6 -0.7 -0.1 -0.9 0.4 -0.7 -0.6 1.4
Arm fat-free mass (left) 0.9 4.5 12.2 3.2 1.9 1.5 0.2 -0.4 -1.0 -0.8 3.0 2.7 -1.5 -0.9 1.8 3.5 3.2
Number of operations (self-reported) 1.1 1.6 3.5 1.5 -0.7 -1.3 -0.6 -1.4 -1.8 -1.8 -0.6 0.7 -1.5 0.3 -1.9 -0.5 1.4
Average weekly beer plus cider intake 0.5 0.8 3.0 -0.5 0.7 0.5 1.4 0.7 1.7 1.1 0.2 -0.4 1.5 -0.2 0.4 0.1 -0.5
Irritability 0.6 1.0 7.1 0.9 -0.1 -0.5 0.9 -0.6 -0.3 -1.2 0.2 0.7 -0.5 0.6 -0.4 1.2 2.7
Risk taking 0.7 1.0 4.7 1.0 1.0 0.2 1.0 0.4 -0.5 -0.4 1.3 0.8 -0.5 -1.7 0.8 2.2 0.3
Ever had prostate specific antigen (PSA) test 0.3 0.3 1.1 0.4 0.6 0.4 0.1 -0.6 0.5 -0.4 -1.0 0.1 0.6 0.9 -1.0 0.1 0.0
Fractured/broken bones in last 5 years 1.7 2.2 7.6 1.1 -1.7 -1.2 0.4 -1.8 -1.7 -1.9 -0.8 0.4 -1.6 0.4 -1.9 0.4 2.8
Age started oral contraceptive pill 1.3 1.7 3.2 1.3 -0.5 -1.8 -1.2 -1.8 -1.6 -1.6 -0.4 0.5 -1.5 0.9 -1.6 0.4 1.3
Diastolic blood pressure, automated reading 0.2 0.7 5.8 0.4 0.2 -0.8 0.6 -0.9 0.2 -0.3 0.3 0.2 -0.0 1.0 0.6 0.9 2.4
Ever depressed for a whole week 1.1 1.3 5.1 1.5 0.2 0.4 1.4 -0.0 -0.3 0.0 1.0 1.5 0.0 0.3 -1.3 2.0 2.3
Unable to work because of sickness or disability 0.4 0.5 1.6 -0.2 -0.8 -1.0 1.3 0.9 0.7 0.4 -0.7 -0.5 0.9 0.3 -0.7 -0.3 0.5
Commuting to job workplace: Cycle 0.8 1.0 3.0 -0.6 -0.4 1.5 -0.2 1.0 1.1 0.6 0.4 -0.1 1.1 -1.6 1.3 -0.4 -1.7
Myopia 0.9 1.3 3.4 1.5 0.5 0.7 1.7 0.5 -0.7 -0.2 1.6 1.3 -0.6 -0.8 -1.2 1.8 1.5
Vascular/heart problems diagnosed by doctor 0.3 0.9 2.5 0.7 -0.2 0.6 -1.6 0.4 -1.4 -0.4 1.0 1.0 -1.2 -1.0 -0.4 0.3 -1.2
Cholesterol lowering medication 1.2 1.7 7.6 1.1 0.9 1.5 1.9 0.4 0.4 -0.3 1.1 0.9 0.1 0.9 -0.2 2.3 2.8
Medication: Omeprazole (e.g. Zanprol) 1.5 1.9 4.5 -1.5 -1.5 -0.5 -2.1 -1.2 -1.3 -0.8 -1.9 -1.8 -1.5 0.4 0.3 -2.0 0.2
Pain experienced in last month 0.4 0.6 3.8 -0.2 0.6 0.1 -0.7 -0.3 -0.4 -0.5 -0.0 -0.4 -0.5 -1.9 0.7 -0.2 -1.7
Supplements: Calcium 0.6 0.6 1.5 0.1 -0.9 -0.9 -0.8 -1.2 -1.0 -1.0 -0.6 -0.3 -1.0 0.2 -1.2 -0.6 0.3
Basal cell carcinoma (self-reported) 1.8 2.1 6.6 -0.5 2.6 1.3 1.2 0.3 0.7 1.9 -0.2 -1.4 0.3 2.5 2.4 1.3 0.4
Heart attack/myocardial infarction (self-reported) 0.8 1.1 4.0 0.4 -1.1 -2.0 -0.9 -1.1 -1.0 -1.0 -0.3 1.0 -0.6 -1.2 -1.7 0.4 -0.1
Deep venous thrombosis (DVT) (self-reported) 1.1 1.5 3.8 -1.8 -0.5 -1.5 -0.7 -0.7 0.0 0.3 -1.6 -1.9 -0.1 1.5 -0.0 -1.9 -1.0
Heart disease (siblings) 0.5 0.6 2.0 -0.4 1.1 0.4 -0.4 1.0 0.8 1.4 -0.1 -0.5 0.9 -0.4 0.4 -0.5 -1.4
Alcohol drinker status: Previous 0.7 0.8 1.9 -0.6 0.9 1.4 1.3 1.2 0.8 1.2 0.3 -0.6 0.5 -0.0 1.0 0.6 -0.4
Pack years of smoking 2.1 3.1 9.8 -0.7 1.6 1.0 2.4 1.8 3.0 2.6 1.4 -0.3 3.1 1.1 1.0 0.6 0.6
Impedance of whole body 1.3 6.5 26.6 -3.9 -2.6 -1.9 0.1 0.2 1.0 0.8 -3.4 -3.2 1.4 0.4 -2.4 -5.2 -2.9
Leg fat mass (left) 0.2 0.7 3.1 1.1 0.9 -1.2 1.0 -0.0 -0.5 -0.2 0.6 0.7 -0.7 0.1 0.3 0.4 1.8
Arm predicted mass (left) 1.0 4.8 13.2 3.4 1.8 1.3 0.1 -0.4 -1.2 -0.7 3.3 3.0 -1.6 -0.8 1.5 3.6 3.2