TWAS hub - WASF1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1410	0.0400	9.5e-07	0.102	NA	0.092	NA	0.114	1.0e-08	NA	5.7e-08	NA	1.4e-09
2	GTEx	Adrenal Gland	0.2153	0.0744	4.6e-03	-0.007	NA	0.034	NA	-0.005	7.7e-01	NA	2.2e-02	NA	5.6e-01
3	GTEx	Artery Aorta	0.1690	0.0470	3.3e-06	0.150	NA	0.144	NA	0.159	1.2e-08	NA	2.5e-08	NA	4.2e-09
4	GTEx	Artery Tibial	0.2152	0.0447	1.5e-10	0.162	NA	0.150	NA	0.160	1.0e-12	NA	7.7e-12	NA	1.4e-12
5	GTEx	Cells Transformed fibroblasts	0.1080	0.0360	4.8e-04	0.029	NA	0.014	NA	0.024	3.0e-03	NA	3.1e-02	NA	6.0e-03
6	GTEx	Heart Atrial Appendage	0.1120	0.0570	9.2e-03	0.037	NA	-0.001	NA	0.002	9.0e-03	NA	3.6e-01	NA	2.6e-01
7	GTEx	Muscle Skeletal	0.1061	0.0341	1.2e-04	0.037	NA	0.052	NA	0.042	1.5e-04	NA	7.8e-06	NA	5.7e-05
8	GTEx	Nerve Tibial	0.3795	0.0544	2.8e-16	0.208	NA	0.237	NA	0.230	1.1e-14	NA	8.8e-17	NA	2.8e-16
9	GTEx	Thyroid	0.0880	0.0330	1.4e-03	0.007	NA	0.047	NA	0.048	9.0e-02	NA	1.5e-04	NA	1.5e-04
10	METSIM	Adipose	0.0388	0.0155	1.5e-03	0.035	0.014	0.029	0.022	0.030	5.0e-06	0.00290	2.6e-05	0.00026	2.2e-05
11	TCGA	Kidney Renal Clear Cell Carcinoma	0.0298	0.0198	3.6e-03	0.021	0.025	0.021	NA	0.023	1.9e-03	0.00064	2.0e-03	NA	1.0e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Lung cancer (father)	4.9	5.7	11.8	1.7	1.6	2.5	2.8	2.9	2.4	1.8	3.4	1.4	2.7	2.2
Ever had hysterectomy (womb removed)	4.4	5.0	8.8	-2.4	-0.1	-2.6	-2.6	-1.8	-2.4	-2.3	-1.6	-2.0	-2.4	-3.0
Average weekly beer plus cider intake	3.9	5.7	8.9	-2.7	-0.6	-2.3	-2.5	-2.6	-2.5	-3.0	-2.5	-1.9	-2.5	-2.4
Fractured/broken bones in last 5 years	3.3	4.2	9.2	2.0	0.0	2.5	2.0	3.0	2.7	1.7	1.1	0.9	2.9	1.6
Vitamin and mineral supplements	3.1	4.2	8.2	1.8	0.2	2.3	2.7	2.5	1.8	1.9	2.9	1.5	2.0	1.6
Serious illness, injury or assault of a close relative in last 2 years	3.1	3.6	5.3	2.3	0.7	2.3	2.0	1.8	2.1	1.8	1.9	1.6	2.0	1.9
Medication: Simvastatin	3.0	4.4	7.4	-1.8	-1.4	-2.2	-2.5	-2.3	-1.7	-2.7	-2.5	-2.3	-2.0	-1.3
Hearing difficulty/problems: Yes	2.7	4.1	6.0	-1.9	-1.1	-2.4	-2.5	-2.4	-2.3	-2.0	-1.9	-1.2	-2.4	-1.6
Mouth/teeth dental problems: Loose teeth	2.6	3.1	8.5	-2.2	-0.8	-1.7	-1.4	-1.1	-1.6	-1.8	-2.2	-2.9	-1.5	-0.9
Wears glasses or contact lenses	2.4	2.8	4.5	1.6	0.4	1.8	1.7	1.5	1.8	2.1	2.0	0.4	1.8	2.1
Hayfever/allergic rhinitis (self-reported)	2.3	3.0	5.2	2.3	1.4	1.9	1.9	0.9	1.5	0.9	2.3	2.3	1.5	1.3
Medication for cholesterol	2.2	3.3	6.6	1.3	1.9	1.6	2.2	1.6	1.6	2.1	2.6	2.2	1.8	0.8
Tinnitus: Yes, now most or all of the time	2.2	2.6	7.5	2.0	-1.5	1.6	0.8	1.6	1.6	2.7	0.2	1.3	1.4	1.7
Illnesses of father: High blood pressure	2.2	2.8	7.6	-1.9	0.6	-1.6	-1.4	-2.8	-1.7	-2.1	-0.8	-1.0	-1.7	-1.4
Pulse rate, automated reading	2.1	6.8	11.1	3.3	1.5	2.9	2.5	1.9	3.3	3.0	2.8	0.5	2.8	2.7
Medication: Lisinopril	2.1	2.8	4.4	-1.8	-0.1	-1.8	-1.8	-2.1	-1.9	-1.8	-0.7	-0.8	-2.0	-2.1
Deep venous thrombosis (DVT) (self-reported)	2.1	2.7	4.2	-1.5	-0.8	-1.7	-1.9	-1.2	-1.8	-1.9	-1.7	-1.0	-2.0	-2.1
Medication: Seretide 50 evohaler	2.0	2.3	3.3	-1.5	-0.3	-1.7	-1.6	-1.6	-1.8	-1.8	-1.2	-0.7	-1.7	-1.8
Time employed in main current job	1.9	2.2	4.4	-1.4	1.6	-1.5	-1.3	-2.1	-1.5	-1.8	-0.3	-0.1	-1.7	-1.7
Blood clot in the leg (DVT)	1.9	2.4	3.6	-1.3	-1.2	-1.6	-1.8	-1.1	-1.6	-1.9	-1.8	-1.0	-1.8	-1.8
Relative age voice broke	1.8	2.7	4.8	-1.7	-0.4	-1.7	-2.2	-0.9	-1.6	-1.7	-1.8	-1.8	-1.7	-1.9
Hair/balding pattern: Pattern 2	1.8	2.3	4.9	2.2	0.8	1.7	1.1	1.6	1.7	1.6	1.3	1.1	1.5	1.4
Had other major operations	1.8	2.2	5.5	-1.5	-0.0	-1.5	-1.7	-1.0	-1.7	-1.8	-1.2	-0.4	-1.6	-2.3
Forced vital capacity (FVC)	1.8	7.1	13.0	2.6	0.5	2.9	3.2	3.6	2.9	2.7	2.2	2.0	3.2	2.0
Loud music exposure frequency	1.8	2.0	3.7	-1.6	-1.9	-1.1	-1.6	-1.1	-1.1	-1.7	-1.9	-1.3	-1.1	-0.1
Supplements: Calcium	1.8	2.0	4.1	-1.1	0.5	-1.5	-1.8	-2.0	-1.4	-0.8	-1.3	-1.2	-1.6	-1.7
Blood Platelet Count	1.7	19.4	34.7	-4.8	-5.9	-4.1	-3.8	-5.1	-4.7	-5.4	-3.3	-2.5	-4.6	-2.9
Ever used hormone-replacement therapy (HRT)	1.7	2.1	5.0	-0.8	-2.2	-1.3	-1.7	-0.9	-1.0	-1.5	-1.9	-2.0	-1.1	-0.8
Hair/balding pattern: Pattern 3	1.7	2.5	4.4	-2.0	-2.1	-1.4	-1.7	-1.4	-1.6	-2.0	-1.2	-0.9	-1.4	-1.5
Asthma	1.7	3.4	5.4	-2.1	-0.4	-2.0	-2.3	-1.9	-1.8	-2.0	-1.6	-1.7	-1.8	-1.9
Medication: Aspirin	1.7	2.2	8.2	-0.5	-2.9	-0.7	-1.8	-1.1	-0.6	-1.9	-2.1	-1.3	-1.0	0.2
Alcohol drinker status: Previous	1.7	2.0	3.5	-1.8	-0.8	-1.4	-1.2	-1.9	-1.7	-1.6	-0.9	-0.9	-1.6	-0.9
Age at First Birth	1.6	2.3	4.8	-1.7	0.4	-1.9	-1.4	-1.6	-1.6	-2.2	-0.7	-0.9	-1.7	-1.7
Medication: Co-codamol	1.6	1.9	5.6	0.7	0.6	1.4	1.6	2.4	1.3	1.2	0.9	1.2	1.8	1.1
Medication: Atenolol	1.6	2.1	6.0	-0.7	-2.5	-0.8	-1.4	-0.7	-0.9	-1.0	-2.3	-2.2	-0.9	-0.9
Frequency of tiredness / lethargy in last 2 weeks	1.6	2.6	4.1	2.0	1.5	2.0	1.8	1.7	1.9	1.4	1.3	0.6	1.9	1.2
Eye problems/disorders: None of the above	1.6	1.8	3.1	-1.4	1.7	-1.1	-0.6	-1.2	-1.6	-1.6	-0.3	-1.0	-1.5	-1.8
Supplements: Vitamin C	1.6	1.9	5.3	-1.0	-1.2	-1.5	-1.8	-1.1	-1.3	-1.1	-2.3	-0.3	-1.6	-0.8
Medication: Aspirin	1.6	2.1	9.3	-0.3	-3.0	-0.4	-1.5	-0.8	-0.4	-1.6	-2.0	-1.6	-0.7	0.4
Ulcerative Colitis	1.5	2.2	10.5	0.8	-3.2	1.4	0.4	1.2	1.2	1.1	-0.6	-0.1	1.3	2.3
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.3	8.1	1.5	1.1	1.5	1.5	2.9	1.5	0.7	1.4	-0.6	1.7	0.7
Mean time to correctly identify matches	1.5	2.9	4.1	-2.0	-1.2	-1.8	-1.9	-1.7	-1.9	-1.8	-1.7	-1.5	-1.6	-1.5
Chest pain or discomfort	1.5	2.2	4.3	-1.2	0.1	-1.4	-2.1	-1.1	-1.2	-1.8	-1.5	-1.7	-1.4	-1.9
Illnesses of father: Heart disease	1.5	2.1	4.5	-0.6	0.8	-1.6	-1.6	-2.1	-1.3	-2.1	-1.1	-0.8	-1.5	-1.5
Supplements: Glucosamine	1.4	1.9	5.2	1.3	0.5	1.2	1.2	1.1	1.3	1.1	1.1	2.3	1.3	1.9
Diabetes (self-reported)	1.4	2.1	6.7	-0.9	-2.6	-1.4	-1.5	-1.4	-1.0	-1.2	-1.1	-2.1	-1.5	-0.1
Medication: Lansoprazole	1.4	1.6	3.2	-1.7	-0.4	-1.2	-1.2	-1.1	-1.7	-1.8	-0.7	-0.8	-1.5	-1.1
Birth weight of first child	1.4	2.5	4.0	1.7	0.7	1.6	1.7	1.6	1.5	1.7	2.0	1.3	1.5	1.9
Worry too long after embarrassment	1.4	2.4	3.9	1.7	-0.5	1.7	1.7	1.8	1.8	2.0	1.1	0.1	1.8	1.6
Had major operations	1.4	1.6	9.9	-0.6	-3.1	-0.5	-0.9	-0.7	-0.7	-0.1	-1.9	-0.7	-0.9	0.1
Average weekly red wine intake	1.4	2.1	5.4	1.4	2.0	1.3	1.5	1.1	1.1	1.6	2.3	0.6	1.2	0.8
Asthma (self-reported)	1.4	2.8	4.6	-1.9	-0.7	-1.8	-2.1	-1.7	-1.7	-1.7	-1.5	-1.5	-1.7	-1.7
Medication: Blood pressure	1.4	2.6	3.5	-1.5	-1.6	-1.5	-1.8	-1.4	-1.7	-1.7	-1.8	-1.9	-1.6	-1.5
Ulcerative Colitis (UC)	1.3	2.4	9.8	1.2	-3.1	1.6	0.9	1.1	1.4	1.0	-0.5	0.2	1.4	2.4
Medication: Ramipril	1.3	1.6	3.7	-1.4	-0.2	-1.1	-1.2	-1.8	-1.1	-0.9	-1.6	-1.9	-1.3	-0.3
Pulse rate	1.3	2.2	4.4	1.8	2.1	1.3	1.6	1.1	1.6	1.6	1.8	0.7	1.4	0.8
Length of working week for main job	1.3	1.4	2.5	0.9	-0.9	1.3	1.5	0.7	1.1	1.6	0.9	1.2	1.2	1.5
Heart disease (mother)	1.3	1.6	2.5	-0.5	0.2	-1.4	-1.6	-1.6	-1.5	-1.1	-1.3	-0.9	-1.6	-1.5
Breast cancer (self-reported)	1.3	1.5	2.9	1.7	-0.1	1.3	1.0	1.1	1.7	1.4	0.9	0.8	1.3	1.4
Guilty feelings	1.3	2.0	5.9	1.2	1.2	1.5	1.4	2.4	1.4	1.0	1.5	0.2	1.5	1.1
Supplements: Zinc	1.2	1.3	2.4	-1.1	-0.5	-1.5	-1.5	-1.3	-1.1	-1.3	-1.2	-0.8	-1.3	-0.6
Medication for cholesterol, blood pressure or diabetes	1.2	2.0	5.0	1.1	0.8	1.2	1.6	2.2	1.0	1.1	2.1	1.4	1.4	0.5
Mother’s age at death	1.2	1.4	2.6	0.8	1.2	1.2	1.3	1.4	1.2	1.6	0.7	0.3	1.3	1.5
Angina	1.1	1.4	2.7	1.0	-0.0	1.6	1.5	1.2	1.2	0.5	1.4	1.2	1.3	1.1
Medication for hormone replacement therapy	1.1	1.2	3.6	-0.7	-0.0	-1.0	-1.1	-1.2	-0.9	-1.3	-1.9	-1.2	-1.2	-0.4
Stomach or abdominal pain in last month	1.1	1.4	3.2	1.3	1.5	1.0	1.4	1.2	1.0	1.0	1.8	0.5	1.0	0.7
Alcohol usually taken with meals	1.1	1.8	2.6	1.0	0.7	1.5	1.5	0.9	1.5	1.4	1.6	1.0	1.6	1.6
Hearing difficulty/problems with background noise	1.1	1.7	2.9	-1.1	-0.5	-1.7	-1.7	-1.6	-1.6	-1.1	-1.0	-0.9	-1.6	-1.2
Forced expiratory volume in 1-second (FEV1)	1.1	3.8	6.9	1.9	-0.3	2.1	2.4	2.6	2.0	2.1	1.5	1.6	2.3	1.5
Medication: Cholesterol lowering	1.1	1.7	4.6	-0.4	-2.1	-0.9	-1.5	-1.7	-0.4	-0.9	-2.1	-1.2	-0.9	0.1
Pulse wave reflection index	1.1	1.4	2.4	-1.4	-1.2	-0.9	-1.3	-1.1	-1.5	-1.6	-0.8	-0.0	-1.4	-0.9
Forced vital capacity (FVC), Best measure	1.1	3.9	7.0	1.9	-0.2	2.2	2.3	2.6	2.1	2.2	1.5	1.6	2.4	1.6
Angina (self-reported)	1.1	1.5	2.8	1.1	-0.3	1.7	1.5	1.2	1.2	0.5	1.4	1.2	1.3	1.3
Illnesses of siblings: Diabetes	1.1	1.4	3.7	0.8	-0.9	1.1	1.1	0.9	1.2	1.7	1.2	-0.6	1.0	1.9
Pain type(s) experienced in last month: Hip pain	1.1	1.3	2.4	1.0	-0.0	1.6	1.0	1.3	1.3	1.1	0.0	1.4	1.4	1.3
Alzheimer’s Disease (in mother)	1.0	1.1	2.8	0.1	0.4	-0.9	-1.6	-1.0	-0.1	-0.9	-1.5	-1.7	-0.6	-1.2
Lung FVC	1.0	5.2	8.1	1.9	0.3	2.4	2.8	2.3	2.2	1.9	2.5	2.8	2.6	2.1
Hand grip strength (right)	1.0	2.7	8.1	1.5	0.5	1.6	1.5	1.9	1.9	2.8	1.4	-0.4	1.9	1.3
Had menopause	1.0	1.3	3.6	-1.1	-1.9	-1.1	-1.1	-0.8	-0.9	-0.9	-1.7	-0.8	-1.0	-0.3
Breastfed as a baby	1.0	1.2	6.2	-0.3	-2.5	-0.3	-1.0	-0.7	-0.4	-1.5	-0.7	1.5	-0.4	-0.5
Hypertension (Self-reported)	1.0	2.9	5.7	-1.9	-1.1	-1.8	-2.1	-1.8	-1.5	-1.0	-1.9	-2.4	-1.6	-1.2
Commuting to job workplace: Walk	1.0	1.0	2.4	1.5	0.3	1.1	0.9	1.0	1.5	0.9	0.6	-0.1	1.4	0.8
Medication: Gliclazide	1.0	1.1	3.2	1.1	-0.7	1.0	1.0	0.4	1.2	1.5	0.8	0.4	0.9	1.8
Alzheimer’s Disease (including proxy)	0.9	1.3	2.6	-0.4	0.9	-1.2	-1.3	-1.2	-0.6	-1.6	-1.1	-1.2	-1.1	-1.3
Lung FEV1/FVC ratio	0.9	4.5	7.8	-2.2	-1.6	-2.2	-2.8	-2.4	-2.2	-1.2	-2.4	-2.2	-2.2	-1.6
Number of treatments/medications taken	0.9	1.6	4.5	-0.8	-1.4	-1.2	-1.7	-1.3	-1.0	-0.7	-2.1	-1.0	-1.2	-0.9
Bilateral oophorectomy (both ovaries removed)	0.9	1.0	1.8	-1.0	0.9	-1.0	-1.3	-0.7	-0.9	-1.2	-1.0	-0.9	-1.0	-1.1
Medication: Ventolin 100micrograms inhaler	0.9	1.2	2.9	-1.1	-1.7	-1.1	-0.9	-0.6	-1.2	-1.4	-0.4	-0.2	-1.0	-1.5
Health satisfaction	0.9	1.2	2.5	-0.9	0.5	-1.2	-1.5	-1.0	-0.8	-1.6	-0.5	-1.2	-1.1	-1.1
Suffer from ‘nerves’	0.9	1.4	3.5	1.0	1.6	1.0	1.1	1.9	0.9	1.4	1.5	-0.3	1.1	-0.1
Family relationship satisfaction	0.9	1.1	2.8	1.7	0.9	1.1	0.9	1.3	1.1	0.3	1.1	-0.7	0.9	1.1
Leg pain on walking	0.9	1.2	2.7	-0.9	-0.2	-1.1	-1.1	-1.1	-1.3	-1.0	-0.8	-0.7	-1.4	-1.6
Long-standing illness, disability or infirmity	0.9	1.4	4.9	-1.4	-2.2	-1.2	-0.9	-1.1	-1.2	-0.9	-1.2	-0.4	-1.1	-0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	2.5	-0.9	1.3	-1.1	-0.8	-0.8	-1.0	-1.2	-0.1	-0.6	-1.0	-1.6
Financial situation satisfaction	0.9	1.1	2.4	-0.8	0.3	-1.1	-1.5	-0.9	-0.9	-1.1	-1.0	-0.8	-1.1	-1.2
High cholesterol (Self-reported)	0.9	1.7	3.3	-1.2	-1.1	-1.3	-1.6	-1.4	-1.1	-1.5	-1.8	-0.8	-1.2	-0.7
Medication: Atorvastatin	0.9	1.2	2.5	1.2	-1.1	1.1	0.7	1.0	1.5	1.1	0.0	0.2	1.2	1.6
Cholesterol lowering medication	0.9	1.3	2.2	-0.9	-1.5	-1.1	-1.5	-0.6	-0.8	-1.3	-1.3	-1.5	-0.9	-0.6
Ovarian Cancer	0.8	1.0	3.0	0.8	-0.9	1.0	0.9	1.0	0.8	1.0	0.6	1.7	1.0	1.0
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	2.1	0.9	-1.2	0.7	0.5	1.4	1.2	0.7	1.0	-0.6	1.0	0.3
Diabetes (father)	0.8	1.0	2.2	-0.6	-1.3	-0.8	-1.3	-1.2	-0.6	-0.9	-1.5	-1.0	-0.8	-0.4
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	3.0	0.8	1.7	0.6	1.1	0.5	0.7	0.4	1.6	-0.3	0.6	0.5
Falls in the last year	0.8	1.1	2.3	0.6	-0.0	1.4	1.2	1.5	0.8	1.1	0.7	1.0	1.1	1.0
Number of live births	0.8	1.2	2.6	-1.3	-0.5	-1.3	-1.6	-0.5	-1.2	-0.9	-0.6	-0.7	-1.1	-1.4
Mouth/teeth dental problems: Mouth ulcers	0.8	1.2	2.8	-1.4	-0.1	-1.1	-0.8	-1.2	-1.7	-1.3	-0.4	0.2	-1.4	-1.1
Average weekly champagne plus white wine intake	0.8	1.1	2.4	0.8	0.3	1.3	0.8	0.8	1.1	1.1	1.2	0.5	1.2	1.6
Vascular/heart problems diagnosed by doctor	0.8	2.2	4.0	1.5	1.6	1.2	1.8	1.4	1.1	0.7	2.0	2.0	1.3	0.9
Waist Hip Ratio (WHR)	0.7	3.1	7.6	-2.0	0.3	-1.9	-1.8	-1.3	-2.0	-2.8	-0.8	-1.2	-1.9	-2.0
Cardiovascular Disease	0.7	2.2	3.7	-1.6	-0.8	-1.6	-1.7	-1.5	-1.7	-1.5	-1.9	-0.7	-1.6	-1.4
Respiratory disease	0.7	1.6	4.1	-1.3	0.4	-1.4	-1.4	-1.0	-1.3	-1.2	-0.7	-1.4	-1.2	-2.0
High blood pressure	0.7	2.1	4.4	-1.5	-1.1	-1.3	-1.8	-1.3	-1.2	-0.6	-1.9	-2.1	-1.3	-0.9
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	1.9	1.4	0.1	0.8	0.8	0.9	1.1	1.1	0.7	-0.3	0.8	1.2
High blood pressure (mother)	0.7	0.9	2.2	1.3	-0.1	1.1	0.9	1.0	1.5	0.4	0.7	0.1	1.5	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.2	3.8	1.2	-0.3	1.6	1.8	1.9	1.5	1.7	1.4	1.3	1.8	1.0
Exposure to tobacco smoke outside home	0.7	1.0	2.2	-1.5	-0.1	-1.1	-1.0	-0.8	-1.1	-1.1	-0.9	-1.1	-0.9	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.9	3.0	-1.0	1.7	-0.1	0.8	-0.3	-0.9	0.7	1.4	1.1	-0.3	-0.2
Medication: Blood pressure	0.7	1.1	3.0	-1.0	0.1	-0.9	-1.0	-1.7	-0.6	-0.8	-1.4	-1.7	-1.0	-0.3
Overall health rating	0.7	1.5	3.1	-1.8	-0.4	-1.2	-1.1	-1.5	-1.7	-1.0	-0.9	-0.1	-1.6	-1.2
Eye problems/disorders: Cataract	0.7	0.8	3.1	-0.9	-1.8	-0.8	-1.2	-0.7	-0.6	-0.4	-1.0	-0.8	-0.6	-0.0
Miserableness	0.7	1.2	1.9	1.0	0.4	1.2	1.4	1.4	0.9	1.1	0.6	1.2	1.1	1.2
Eye problems/disorders: Glaucoma	0.7	0.8	1.3	1.1	-1.0	1.0	0.5	0.9	1.1	0.7	0.4	0.2	1.1	1.2
Coronary Artery Disease (CAD)	0.6	0.7	1.6	-0.8	0.5	-0.5	-0.6	-1.1	-1.1	-0.9	-1.3	0.3	-1.0	-0.7
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	1.3	-0.8	-0.3	-1.0	-1.1	-1.1	-0.7	-1.1	-1.0	0.2	-0.9	-0.6
Age when periods started (menarche)	0.6	1.3	2.2	-1.5	-1.5	-1.3	-1.4	-1.0	-0.9	-0.5	-1.5	-0.6	-1.0	-0.9
Serious illness, injury or assault to yourself	0.6	0.7	1.6	1.3	-0.8	1.0	0.7	1.0	1.0	0.7	-0.1	-0.2	0.9	0.8
Sitting height	0.6	4.2	19.6	1.8	-1.9	1.6	1.8	2.4	1.7	4.4	0.1	0.1	1.8	1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	2.8	0.1	0.7	0.7	1.0	1.7	0.4	0.9	1.5	0.6	0.8	0.6
Hair/balding pattern: Pattern 4	0.6	1.4	3.0	-1.5	0.7	-1.2	-1.0	-1.7	-1.3	-1.2	-0.7	-1.0	-1.4	-0.5
Age at first live birth	0.6	1.0	2.2	1.2	0.2	1.2	0.8	0.6	1.3	0.4	1.3	0.7	1.1	1.5
Medication for pain relief, constipation, heartburn	0.6	1.1	4.8	-0.1	2.2	0.1	1.0	0.3	0.1	1.1	2.1	-0.9	0.3	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.8	1.4	1.1	0.3	1.0	0.9	0.9	0.9	0.3	0.9	1.2	1.0	0.4
Number of full sisters	0.6	0.7	1.4	-0.9	-0.8	-0.7	-0.9	-0.6	-1.0	-1.2	-0.7	-0.2	-1.0	-0.7
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	2.6	-1.6	-0.4	-1.2	-0.7	-0.8	-1.0	-0.1	-0.7	-0.4	-0.8	-0.7
Diabetes diagnosed by doctor	0.6	0.9	4.8	-0.5	-2.2	-0.8	-0.8	-0.7	-0.4	-0.4	-0.9	-1.2	-0.8	0.4
Osteoporosis (self-reported)	0.6	0.8	3.5	-0.3	1.9	0.5	1.2	0.5	-0.1	0.2	0.8	1.0	0.5	-0.8
Hearing aid user	0.6	0.7	2.0	-0.8	-0.4	-0.7	-1.4	-0.8	-0.6	-0.9	-1.0	-0.9	-0.9	-0.4
Bipolar Disorder (2018)	0.5	0.8	2.1	-1.1	-1.1	-0.7	-0.4	-0.8	-1.2	-1.4	-0.8	0.3	-1.0	-0.2
Depressed Affect (Nagel 2018)	0.5	1.1	2.7	1.3	-0.4	1.0	0.7	1.6	1.0	1.1	0.5	0.5	1.0	1.6
Neuroticism (Nagel 2018)	0.5	1.1	3.5	1.2	-0.2	0.9	0.8	1.9	1.2	0.8	0.5	-0.5	1.2	1.0
Irritable Bowel Disease (IBD)	0.5	1.2	8.8	0.4	-3.0	0.7	0.1	0.7	0.4	0.4	-1.0	-0.1	0.5	1.1
Major Depression (MDD)	0.5	0.6	1.3	-0.3	-0.9	-0.6	-0.8	-0.5	-1.0	-0.6	-1.1	0.4	-1.0	-0.3
Reaction Time	0.5	1.0	1.5	-0.9	-0.4	-1.1	-1.1	-0.8	-1.1	-1.1	-0.8	-0.8	-1.0	-1.2
Crohns Disease (2012)	0.5	0.8	2.8	0.3	-1.0	0.7	0.9	1.0	0.4	0.6	1.0	1.7	0.7	1.0
LDL Cholesterol	0.5	0.8	4.2	-0.6	0.7	-0.4	-0.8	-0.2	-0.4	-2.1	-0.8	-1.0	-0.4	-0.6
Rheumatoid Arthritis	0.5	0.7	2.7	0.5	1.6	0.7	0.5	0.1	0.8	1.2	0.3	-0.8	0.8	0.5
Schizophrenia (2014)	0.5	1.1	3.4	0.6	0.1	1.3	1.4	1.4	0.5	0.3	1.2	1.8	1.2	0.2
Type 2 Diabetes (T2D) (2012)	0.5	0.5	2.6	-0.5	-1.6	-0.2	-0.3	-0.9	-0.8	-0.4	-0.9	0.5	-0.7	0.1
Pack years adult smoking proportion	0.5	0.7	1.8	-0.5	-1.4	-0.7	-1.0	-0.6	-0.5	-0.9	-1.2	-0.2	-0.8	-0.6
Nervous feelings	0.5	0.9	3.0	0.5	1.7	0.5	1.0	1.2	0.4	0.0	1.6	-0.3	0.7	-0.4
Pain all over the body in last month	0.5	0.6	1.6	-1.2	-0.3	-0.6	-0.3	-0.2	-1.3	-0.1	-0.9	-0.3	-0.9	-1.0
Qualifications: A levels/AS levels or equivalent	0.5	1.1	2.7	1.1	-0.0	0.6	1.1	1.6	0.9	0.6	1.4	1.6	1.0	-0.0
Prospective memory result	0.5	0.6	3.5	-0.4	-0.0	-0.9	-0.6	-1.0	-0.5	-0.0	-0.5	-1.9	-0.7	-0.5
Birth weight	0.5	1.2	10.4	0.0	-3.2	0.2	0.1	0.2	0.3	0.2	-0.9	-0.1	0.3	1.1
Medication: Ibuprofen	0.5	0.6	2.6	-0.8	0.4	-0.9	-0.9	-0.9	-0.2	-0.2	-1.0	-1.6	-0.5	-0.2
Age at last live birth	0.5	0.7	1.4	0.8	-0.4	0.8	0.9	0.8	0.9	0.4	1.2	1.1	0.9	0.9
Smoking status: Previous	0.5	0.7	1.5	1.0	1.2	1.0	0.7	0.6	1.0	0.5	0.4	0.5	0.9	1.0
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.7	1.0	1.0	0.8	0.6	0.3	0.8	1.3	0.1	-0.0	0.6	0.9
Diastolic blood pressure, automated reading	0.5	1.5	5.2	0.8	2.3	1.1	1.5	1.0	0.8	1.5	1.4	0.6	1.1	0.7
Pack years of smoking	0.5	0.8	3.1	-0.4	-1.8	-0.6	-0.9	-0.5	-0.5	-0.9	-1.4	-0.1	-0.8	-0.5
Bipolar Disorder (2011)	0.4	0.4	1.1	-0.5	-1.0	0.1	0.3	-0.4	-0.7	-0.9	0.0	0.8	-0.5	0.4
Taking other prescription medications	0.4	0.6	1.9	-1.0	-1.4	-0.6	-0.7	-0.6	-0.9	-0.6	-0.8	-0.0	-0.8	-0.0
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.8	-0.5	-1.3	-0.6	-0.7	-0.7	-0.6	-0.2	-0.4	-1.1	-0.8	0.4
Neuroticism score	0.4	0.8	2.5	1.0	0.7	0.9	0.7	1.6	0.9	0.4	0.8	0.0	1.0	0.7
Trunk fat-free mass	0.4	2.1	9.0	1.4	-0.3	1.4	1.0	1.9	1.3	3.0	0.2	-0.6	1.4	0.9
Noisy workplace	0.4	0.5	1.4	-0.6	-0.6	-0.5	-0.5	-0.7	-0.8	-0.9	-1.2	0.2	-0.7	-0.5
Illnesses of mother	0.4	0.4	1.7	0.2	-0.3	0.7	0.9	0.5	0.1	0.3	1.3	1.0	0.2	0.6
Impedance of arm (left)	0.4	1.7	2.9	-1.4	-0.9	-1.4	-1.1	-1.0	-1.7	-1.5	-1.1	-0.6	-1.6	-1.7
Trunk predicted mass	0.4	2.4	9.9	1.5	-0.2	1.6	1.2	2.1	1.5	3.1	0.3	-0.5	1.5	1.0
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	3.2	0.4	0.7	-0.2	0.2	0.6	-0.3	0.2	1.2	1.8	-0.2	-1.1
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	0.9	-0.6	0.9	-0.4	-0.7	-0.8	-0.9	-0.5	0.1	-0.7	-1.0	-0.6
Medication: Amlodipine	0.4	0.6	3.8	-0.2	-1.9	-0.3	-0.7	-0.2	-0.1	0.3	-1.0	-1.0	-0.1	0.2
Arm fat-free mass (right)	0.4	2.3	9.1	1.6	-0.1	1.5	0.9	2.0	1.6	3.0	0.4	-0.4	1.5	1.0
Wheeze or whistling in the chest in last year	0.4	0.7	2.5	-0.4	0.1	-0.6	-1.2	-0.7	-0.4	-0.8	-0.7	-1.6	-0.7	-1.0
Arm predicted mass (right)	0.4	2.0	8.0	1.4	-0.1	1.4	0.9	1.9	1.5	2.8	0.2	-0.4	1.4	0.9
Knee pain experienced in last month	0.4	0.6	2.3	-0.2	-0.6	-0.5	-1.2	-0.8	-0.4	-0.3	-1.5	-0.6	-0.5	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	3.4	1.1	-0.3	0.8	0.6	1.1	0.9	1.8	-0.2	-0.0	1.0	0.7
Mineral and other dietary supplements	0.4	0.6	3.2	-0.9	-1.8	-0.4	-0.3	0.2	-0.7	-0.8	-0.1	-0.3	-0.5	-0.8
Osteoarthritis (self-reported)	0.4	0.5	1.6	0.0	-0.0	0.6	0.6	0.7	0.4	1.3	0.2	1.0	0.6	1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	7.6	0.0	-2.8	0.2	-0.2	0.3	0.0	-0.4	-0.9	0.2	0.1	0.7
Number of self-reported non-cancer illnesses	0.4	0.7	1.5	-0.8	-1.2	-0.7	-1.0	-0.7	-0.8	-0.1	-1.2	-0.5	-0.9	0.4
Supplements: Fish oil (including cod liver oil)	0.4	0.5	3.7	0.3	1.9	-0.2	-0.1	-1.0	0.3	0.5	-0.3	-0.4	-0.0	0.3
Arm fat-free mass (left)	0.4	1.9	7.6	1.5	-0.1	1.4	0.9	1.9	1.5	2.8	0.3	-0.0	1.4	0.8
Number of operations (self-reported)	0.4	0.5	1.6	-1.0	-0.7	-0.6	-0.9	-0.3	-0.8	-0.1	-1.3	0.1	-0.7	-0.6
Risk taking	0.4	0.6	2.5	0.4	-0.1	0.7	0.9	0.8	0.4	0.8	0.6	1.6	0.6	0.4
Age started oral contraceptive pill	0.4	0.5	3.0	0.5	-1.7	0.2	-0.2	0.6	0.9	-0.5	-0.2	-0.5	0.7	0.6
Myopia	0.4	0.5	4.6	-0.3	0.6	-0.1	-0.2	-0.3	-0.0	-0.7	-0.4	-2.1	-0.1	0.0
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.8	-0.8	-0.7	-0.5	-0.4	-0.3	-1.0	-0.4	-0.1	1.3	-0.9	-0.7
Schizophrenia (2018)	0.3	0.7	1.6	0.2	0.5	0.9	1.2	1.2	0.5	0.2	1.3	0.5	1.1	-0.1
Schizophrenia vs Biploar Disorder	0.3	0.4	0.8	0.5	-0.5	0.5	0.1	0.5	0.6	0.9	-0.9	0.1	0.8	-0.6
Worry (Nagel 2018)	0.3	0.6	1.8	0.8	0.6	0.6	0.6	1.3	0.8	0.2	0.8	-0.9	0.8	-0.1
Alzheimer’s Disease (in father)	0.3	0.3	1.2	-0.3	0.3	-0.5	-0.2	-0.9	-0.3	-1.1	-0.3	0.2	-0.5	-0.6
Mean Putamen Volume	0.3	0.3	2.5	-0.1	1.6	0.0	-0.0	-0.3	0.2	-0.6	-0.3	0.1	0.2	0.1
Neuroticism	0.3	0.6	2.3	1.1	-0.5	0.7	0.2	1.5	1.0	0.2	0.4	-0.5	0.7	0.8
Average weekly spirits intake	0.3	0.4	1.4	0.0	0.6	-0.4	-0.5	-0.4	-0.5	-1.2	-0.6	-0.4	-0.8	-0.5
Medication: Metformin	0.3	0.4	0.9	0.9	-0.3	0.5	0.5	0.4	0.9	0.3	0.7	0.5	0.5	1.0
Severe depression (siblings)	0.3	0.3	0.8	-0.5	0.7	-0.9	-0.4	-0.8	-0.7	-0.5	-0.0	0.1	-0.7	-0.4
Impedance of leg (right)	0.3	1.4	2.2	-1.0	-1.1	-1.4	-1.3	-0.8	-1.5	-1.3	-1.3	0.2	-1.4	-1.2
Maternal smoking around birth	0.3	0.4	1.4	0.0	1.2	0.1	0.7	0.5	-0.5	-0.3	0.6	1.1	-0.3	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	1.8	-0.8	0.5	-1.0	-0.9	-1.4	-0.9	-0.5	-0.4	-1.0	-1.0	-0.2
Hayfever, allergic rhinitis or eczema	0.3	0.7	1.1	1.0	-1.0	0.8	0.7	0.9	0.7	0.6	0.6	1.0	0.8	0.9
Chronic bronchitis/emphysema (father)	0.3	0.4	0.8	0.8	0.8	0.7	0.8	0.3	0.6	0.9	0.1	0.5	0.5	0.6
Number of incorrect matches in round	0.3	0.5	3.4	-0.4	1.9	-0.3	-0.2	-0.4	-0.3	0.1	-0.3	-0.2	-0.2	-1.0
Past tobacco smoking	0.3	0.6	1.2	-1.1	-0.8	-0.9	-0.5	-0.7	-0.9	-0.5	-0.3	-0.6	-0.8	-0.8
Financial difficulties in last 2 years	0.3	0.4	1.5	-0.1	-0.4	-0.4	-1.0	-0.2	-0.5	-0.4	-0.5	-0.9	-0.5	-1.2
Mouth/teeth dental problems	0.3	0.5	1.7	0.9	0.4	0.5	0.7	0.6	0.8	0.7	0.5	1.3	0.8	0.1
Heart attack	0.3	0.4	0.9	0.4	-0.0	0.7	0.6	0.4	1.0	0.4	-0.5	-0.6	0.9	0.8
Impedance of arm (right)	0.3	1.3	3.1	-1.1	-0.3	-1.2	-0.8	-0.8	-1.5	-1.4	-1.0	-0.0	-1.3	-1.8
Worrier / anxious feelings	0.3	0.5	1.1	1.0	-0.1	0.7	0.4	1.0	0.8	0.2	0.8	-0.5	0.7	0.7
Happiness	0.3	0.4	1.4	-0.6	1.2	-0.5	-0.7	-0.2	-0.5	-0.7	-0.2	-0.7	-0.5	0.3
Mouth/teeth dental problems: Dentures	0.3	0.6	1.3	0.5	-0.6	0.8	0.6	1.0	0.8	1.1	-0.5	-0.3	0.9	0.9
Peak expiratory flow (PEF)	0.3	0.6	2.8	0.4	-1.7	0.3	0.4	0.9	0.5	1.2	-0.2	0.0	0.6	0.5
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.4	0.6	-1.2	0.5	-0.3	0.2	0.2	0.2	-0.5	0.5	0.1	1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.3	0.2	-0.5	0.8	0.7	1.1	0.1	0.3	1.1	-0.0	0.4	0.6
Migraine (self-reported)	0.3	0.3	1.4	-0.5	-1.2	-0.4	-0.5	-0.1	-0.3	-0.8	-0.8	0.4	-0.3	-0.1
Alcohol intake frequency.	0.3	0.6	1.6	-0.9	-1.0	-0.8	-0.3	-1.3	-0.9	-0.7	0.3	-0.1	-1.1	-0.2
Comparative height size at age 10	0.3	1.6	5.4	1.4	-0.1	1.7	1.5	1.8	0.8	2.3	0.0	-0.2	1.1	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	0.9	-0.4	-0.1	-0.2	-0.4	-0.5	-0.7	-0.6	-0.7	0.7	-0.5	-0.9
Whole body fat-free mass	0.3	1.9	8.4	1.4	0.1	1.4	1.0	1.9	1.4	2.9	0.3	-0.5	1.3	0.6
Leg fat-free mass (right)	0.3	1.5	5.7	1.3	0.5	1.3	1.0	1.6	1.2	2.4	0.5	-0.6	1.1	0.3
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.5	-0.9	0.7	-0.4	0.1	-0.4	-0.7	0.1	0.3	0.5	-0.4	-1.2
Ever had bowel cancer screening	0.3	0.4	1.2	-0.2	-1.1	-0.5	-0.8	-0.6	-0.5	-1.0	-0.4	-0.3	-0.6	0.2
Qualifications: nursing, teaching	0.3	0.4	2.0	-0.3	0.6	-0.4	-0.3	-0.6	-0.5	-0.4	0.2	-1.4	-0.5	-0.7
Back pain experienced in last month	0.3	0.4	0.8	-0.8	0.9	-0.5	-0.1	-0.3	-0.8	-0.6	0.1	0.6	-0.4	-0.9
Illnesses of father: None of the above (group 1)	0.3	0.4	2.1	0.2	-0.1	0.6	0.6	1.5	0.6	0.7	0.3	0.3	0.7	0.7
Whole body water mass	0.3	1.8	8.0	1.4	-0.0	1.4	0.9	1.8	1.3	2.8	0.2	-0.5	1.3	0.6
Leg predicted mass (right)	0.3	1.6	5.8	1.4	0.5	1.3	1.1	1.6	1.3	2.4	0.6	-0.5	1.2	0.4
Ever taken oral contraceptive pill	0.3	0.3	1.4	0.2	-0.4	-0.4	-0.4	-0.5	-0.2	-1.2	-1.0	-0.5	-0.4	0.0
Medication: Paracetamol	0.3	0.4	1.1	1.1	0.9	0.6	0.2	0.6	0.6	0.0	-0.1	0.8	0.5	-0.7
Alcohol drinker status: Never	0.3	0.3	1.0	0.2	-0.3	0.4	0.9	0.4	0.4	0.1	0.9	1.0	0.6	0.5
Basal metabolic rate	0.3	1.6	7.2	1.4	-0.1	1.3	0.8	1.7	1.2	2.7	0.1	-0.6	1.2	0.5
Unable to work because of sickness or disability	0.3	0.4	1.7	-0.3	1.3	-0.2	-0.2	-0.5	-0.4	-0.6	0.7	0.5	-0.4	-0.7
Pain experienced in last month	0.3	0.4	1.2	0.5	0.4	0.7	0.8	0.7	0.8	-0.1	1.1	-0.0	0.7	0.7
Impedance of whole body	0.3	1.8	3.0	-1.4	-0.9	-1.5	-1.1	-1.1	-1.7	-1.6	-1.2	-0.0	-1.5	-1.7
Arm predicted mass (left)	0.3	1.7	6.9	1.4	-0.0	1.4	0.7	1.7	1.4	2.6	0.2	-0.2	1.3	0.6
Depression (Nagel 2018)	0.2	0.3	0.8	0.3	-0.8	-0.2	-0.9	0.6	0.1	0.1	-0.7	-0.8	0.0	-0.0
Body Mass Index (BMI) (2010)	0.2	0.2	0.6	-0.1	-0.4	-0.3	-0.6	-0.5	-0.4	-0.0	-0.4	-0.8	-0.5	-0.6
Fasting Glucose	0.2	0.3	1.9	-0.2	0.7	0.2	-0.3	0.2	-0.4	0.4	-0.1	1.4	-0.1	-0.5
Lupus	0.2	0.3	2.0	0.3	0.0	-0.3	-0.3	0.1	-0.2	-1.4	-0.3	0.8	-0.3	-0.5
Blood Red Count	0.2	2.2	3.2	-1.6	1.4	-1.7	-1.3	-1.7	-1.8	-0.1	-0.8	-1.5	-1.8	-1.7
Height	0.2	3.7	10.3	-0.7	-2.6	-1.1	-1.5	-0.1	-1.1	2.6	-3.2	-2.7	-1.1	-1.5
Systolic Blood Pressure	0.2	1.0	2.6	-0.9	0.1	-1.2	-0.9	-1.0	-1.3	-0.5	-1.6	-0.6	-1.0	-1.3
Smoking Status	0.2	0.4	1.1	0.7	0.4	0.7	0.7	1.0	0.4	0.4	0.5	1.0	0.4	0.6
Chronotype (morning person)	0.2	0.4	1.9	-0.1	1.4	-0.1	-0.7	-0.4	-0.1	-0.2	-0.2	-0.2	-0.0	-1.2
Systolic blood pressure, automated reading	0.2	0.5	1.1	-0.4	0.8	-0.8	-0.5	-1.0	-0.9	0.3	-0.5	-0.4	-0.7	-1.0
Leg fat-free mass (left)	0.2	1.2	5.3	1.1	0.3	1.1	0.7	1.4	1.0	2.3	0.3	-0.7	0.9	0.3
Trunk fat percentage	0.2	0.6	1.8	-0.5	-0.6	-0.7	-1.3	-0.6	-0.7	-0.2	-1.0	-0.4	-0.9	-1.2
Townsend deprivation index at recruitment	0.2	0.2	0.6	-0.5	0.7	-0.2	-0.5	0.0	-0.4	-0.3	-0.8	0.2	-0.2	-0.7
Current tobacco smoking	0.2	0.4	1.6	-0.5	0.5	-0.7	-0.7	-0.1	-0.5	-0.7	-0.4	-0.2	-0.5	-1.3
Fed-up feelings	0.2	0.3	1.0	0.2	-1.0	-0.2	-1.0	-0.2	-0.2	-0.9	-0.6	0.0	-0.4	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	1.4	0.4	-1.2	0.0	-0.5	1.1	0.3	0.3	-0.3	-0.4	0.2	-0.2
Multivitamins +/- minerals	0.2	0.3	1.0	0.2	0.5	-0.5	-0.7	-0.6	-0.1	-0.1	-1.0	-0.1	-0.3	-0.5
Medication: Levothyroxine sodium	0.2	0.4	0.8	-0.5	-0.8	-0.6	-0.7	-0.9	-0.5	-0.5	-0.5	-0.5	-0.7	0.4
Impedance of leg (left)	0.2	1.0	1.4	-0.7	-0.9	-1.1	-1.0	-0.7	-1.2	-1.2	-0.9	0.6	-1.1	-1.1
Leg predicted mass (left)	0.2	1.2	5.2	1.2	0.5	1.1	0.7	1.5	1.1	2.3	0.4	-0.6	1.0	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.0	-0.6	0.8	-0.7	-0.3	-0.8	-0.8	0.4	-0.2	-1.0	-0.9	-0.1
Qualifications: None of the above	0.2	0.4	1.7	0.4	0.5	0.2	-0.1	0.3	0.8	0.4	-0.7	-1.3	0.4	0.8
Allergy	0.2	0.4	2.4	-0.8	1.5	-0.4	-0.0	-0.5	-0.4	-0.3	0.2	-0.7	-0.4	-0.3
Father’s age at death	0.2	0.3	0.6	0.7	-0.1	0.5	0.4	0.6	0.6	0.7	-0.2	0.6	0.6	0.5
Depression (self-reported)	0.2	0.2	0.7	0.3	0.0	0.2	0.8	0.5	-0.0	0.6	0.4	0.8	0.3	0.3
Pulse wave Arterial Stiffness index	0.2	0.2	1.0	0.4	-1.0	0.3	0.3	0.7	0.0	-0.2	0.2	-0.0	0.1	0.3
Standing height	0.2	2.0	11.6	0.7	-1.6	0.6	0.5	1.7	0.5	3.4	-1.2	-1.3	0.6	0.0
Tense / ‘highly strung’	0.2	0.4	1.0	0.1	1.0	0.4	1.0	1.0	0.1	0.1	0.2	0.8	0.4	-0.1
Medication: Paracetamol	0.2	0.3	0.8	0.6	0.0	0.3	-0.2	0.4	0.1	-0.7	-0.8	0.5	0.1	-0.9
Headache pain in last month	0.2	0.4	1.4	0.0	-1.2	-0.2	-0.5	-0.4	-0.4	-0.5	-0.9	0.8	-0.5	0.1
Glaucoma (self-reported)	0.2	0.2	0.6	0.4	-0.8	0.3	-0.0	0.3	0.5	0.1	-0.4	-0.7	0.4	0.8
Gout (self-reported)	0.2	0.3	1.2	-0.3	0.5	-0.5	-0.5	-1.1	-0.5	-0.7	-0.1	0.6	-0.6	-0.4
Hypothyroidism/myxoedema (self-reported)	0.2	0.5	1.3	-0.4	-0.7	-0.6	-0.7	-0.8	-0.5	-0.5	-0.6	-1.1	-0.7	0.6
Comparative body size at age 10	0.2	0.5	1.7	-0.3	-0.7	-0.5	-1.1	-1.2	-0.3	-1.3	-0.4	-0.3	-0.5	-0.5
Number of full brothers	0.2	0.3	1.1	-0.6	-0.6	-0.6	-0.8	0.1	-0.2	-1.1	-0.3	-0.3	-0.3	-0.2
Pulse wave peak to peak time	0.2	0.2	0.9	-0.5	1.0	-0.3	-0.4	-0.6	-0.0	0.3	-0.3	-0.2	-0.1	-0.3
Neck or shoulder pain in last month	0.2	0.3	1.4	-0.3	1.2	-0.3	-0.2	-0.6	-0.3	-0.1	0.2	0.6	-0.2	-0.8
Medication: Allopurinol	0.2	0.2	0.8	-0.4	0.2	-0.3	-0.1	-0.8	-0.6	-0.5	0.2	0.9	-0.6	-0.0
Mood swings	0.2	0.4	1.3	0.4	-0.6	0.4	-0.0	1.1	0.5	-0.2	0.5	-0.6	0.5	1.0
Friendships satisfaction	0.2	0.2	1.0	0.4	-1.0	-0.0	-0.1	-0.1	0.2	-0.3	0.1	-0.4	0.1	1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	2.5	-0.1	-0.5	-0.3	-0.3	-0.3	-0.1	-0.1	-0.3	1.6	-0.1	-0.1
Commuting to job workplace: Public transport	0.2	0.3	1.2	-0.4	-0.1	-0.6	-1.1	-0.1	-0.4	-0.1	-0.2	-0.7	-0.4	-0.8
Medication: Bendroflumethiazide	0.2	0.3	1.2	-0.1	-1.1	-0.2	-0.3	-0.4	0.1	0.5	-1.0	-1.1	0.0	0.3
Irritability	0.2	0.4	1.0	0.8	1.0	0.4	0.2	1.0	0.7	-0.0	0.5	-0.2	0.6	0.2
Ever depressed for a whole week	0.2	0.2	1.0	0.3	1.0	0.2	-0.4	-0.4	0.3	-0.7	0.4	-0.5	0.0	0.2
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.8	0.3	-0.2	0.6	0.5	0.3	0.9	0.2	-0.6	-0.6	0.8	0.7
Bipolar Disorder or Schizophrenia	0.1	0.2	0.6	-0.5	-0.3	0.2	0.7	0.4	-0.4	-0.8	0.5	0.5	0.3	-0.2
Intelligence (Savage-Jansen 2018)	0.1	0.3	2.4	-0.2	-1.5	0.0	-0.2	0.1	-0.3	-0.2	-0.1	0.0	-0.4	0.7
Crohns Disease (2017)	0.1	0.3	0.7	-0.5	-0.8	-0.4	-0.4	0.1	-0.8	-0.2	-0.5	0.3	-0.6	-0.6
Verbal and Numeric Reasoning (VNR)	0.1	0.3	0.6	-0.5	-0.8	-0.4	-0.6	-0.5	-0.6	-0.8	-0.1	-0.0	-0.7	-0.0
Breast Cancer	0.1	0.2	0.7	-0.2	-0.8	-0.3	-0.2	0.4	-0.2	-0.5	-0.5	-0.4	-0.1	-0.3
HbA1C	0.1	0.1	0.4	-0.5	0.3	-0.0	0.0	-0.1	-0.7	0.6	0.1	-0.1	-0.4	-0.1
HDL Cholesterol	0.1	0.1	0.4	0.2	0.5	-0.3	-0.5	-0.2	0.0	0.2	0.0	0.7	-0.1	-0.6
Neuroticism (2016)	0.1	0.2	0.7	0.4	-0.1	-0.0	-0.4	0.8	0.1	0.2	-0.4	-0.7	0.0	-0.6
Primary Biliary Cirrhosis	0.1	0.1	0.6	-0.2	-0.6	0.2	0.2	0.1	-0.2	0.2	0.3	-0.2	-0.0	0.7
Triglycerides	0.1	0.2	1.0	0.1	-0.7	0.6	0.2	0.4	0.0	-1.0	-0.2	-0.1	0.2	0.5
Blood Eosinophil Count	0.1	0.9	3.5	1.2	0.7	0.9	0.4	0.1	0.9	-0.4	1.9	0.6	0.7	1.0
Heel T-Score	0.1	0.5	2.0	-0.6	1.4	-0.3	-0.6	-1.1	-0.4	-0.7	-0.5	0.7	-0.6	-0.2
Allergy or Eczema	0.1	0.4	2.3	0.6	-1.5	0.3	-0.0	0.5	0.0	0.0	0.0	0.7	0.1	0.5
Hypothyroidism (self reported)	0.1	0.1	1.0	-0.3	-1.0	-0.0	-0.2	-0.2	-0.2	-0.3	-0.2	-0.1	-0.1	0.6
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.7	0.2	-0.9	-0.2	-0.4	-0.3	-0.1	-0.4	-0.0	-0.4	-0.5	0.5
Hand grip strength (left)	0.1	0.3	1.5	0.5	0.4	0.5	0.1	0.6	0.8	1.2	0.1	-0.4	0.6	-0.1
Sensitivity / hurt feelings	0.1	0.2	0.6	0.4	-0.5	0.1	-0.2	0.7	0.4	-0.5	-0.7	-0.5	0.4	0.2
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.6	0.5	0.4	-0.2	-0.8	0.6	0.0	0.1	-0.2	-0.2	-0.1	-0.6
Relative age of first facial hair	0.1	0.1	0.4	-0.1	0.6	-0.4	-0.1	-0.2	-0.4	0.5	-0.0	-0.3	-0.6	-0.3
Average weekly fortified wine intake	0.1	0.2	0.3	0.5	0.0	0.1	-0.1	0.4	-0.0	-0.6	-0.5	0.6	-0.1	0.6
Qualifications: CSEs or equivalent	0.1	0.2	1.0	0.2	-0.2	-0.1	-0.2	-0.1	-0.1	0.0	-0.2	0.9	-0.2	-1.0
Trunk fat mass	0.1	0.4	0.9	-0.0	-0.8	-0.2	-0.9	-0.0	-0.2	0.7	-0.9	-0.6	-0.4	-0.8
Waist circumference	0.1	0.3	1.1	-0.1	-1.0	-0.2	-0.9	-0.1	-0.2	0.0	-0.4	-1.0	-0.4	-0.5
Fluid intelligence score	0.1	0.1	0.3	0.3	-0.2	0.6	0.2	0.2	0.3	0.5	0.4	-0.2	0.3	0.5
Illnesses of siblings	0.1	0.1	0.7	-0.0	0.4	0.2	0.3	0.3	-0.1	-0.2	0.3	0.9	-0.1	-0.1
Weight	0.1	0.7	3.8	0.9	-0.5	0.7	0.1	0.9	0.8	2.0	-0.2	-0.6	0.6	0.3
Arm fat percentage (right)	0.1	0.3	0.9	-0.2	-0.3	-0.4	-1.0	-0.5	-0.4	-0.3	-0.4	-0.5	-0.6	-0.8
Hip circumference	0.1	0.4	1.7	0.5	-1.1	0.5	-0.2	0.4	0.4	1.3	-0.2	0.0	0.3	0.0
Alcohol intake versus 10 years previously	0.1	0.2	0.4	0.4	0.6	0.0	-0.5	-0.1	0.5	0.2	-0.4	-0.7	0.1	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.2	1.6	0.0	1.3	-0.0	-0.2	-0.2	0.4	-0.0	-0.2	-0.3	0.3	0.1
Exposure to tobacco smoke at home	0.1	0.1	0.5	0.5	0.7	0.3	0.3	0.0	0.4	-0.2	0.4	-0.1	0.3	-0.3
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.4	-0.5	0.1	-0.4	0.0	0.1	-0.3	-0.1	-0.2	0.2	-0.3	-0.6
High blood pressure (siblings)	0.1	0.2	1.4	0.4	0.2	-0.2	-0.4	-0.5	0.3	0.5	-0.2	-1.2	0.0	-0.1
Body fat percentage	0.1	0.3	1.2	-0.0	-0.5	-0.4	-1.1	-0.3	-0.3	-0.0	-0.7	-0.1	-0.5	-0.7
Number of children fathered	0.1	0.1	0.5	-0.7	-0.2	-0.0	-0.1	-0.1	-0.2	0.3	-0.1	0.5	0.0	-0.3
Shortness of breath walking on level ground	0.1	0.1	0.4	0.6	0.1	0.2	0.3	0.3	0.1	0.5	0.1	0.1	-0.1	0.2
Qualifications: College or University degree	0.1	0.5	1.2	0.2	-0.8	0.5	0.9	1.1	0.5	0.6	0.8	-0.1	0.7	0.7
Emphysema/chronic bronchitis	0.1	0.1	0.6	-0.2	-0.4	0.0	-0.3	0.5	-0.4	-0.1	-0.2	-0.2	-0.3	-0.8
Medication: Omeprazole	0.1	0.1	0.8	-0.2	-0.6	0.2	0.2	0.3	-0.2	0.3	0.4	0.9	-0.1	-0.1
Whole body fat mass	0.1	0.3	0.8	0.2	-0.7	-0.1	-0.9	0.2	0.0	0.7	-0.7	-0.4	-0.2	-0.5
Commuting to job workplace: Car/motor vehicle	0.1	0.2	0.7	-0.0	0.7	0.1	0.3	-0.2	-0.3	-0.0	0.1	0.8	-0.2	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.2	0.0	-0.0	0.3	0.0	0.4	0.3	-0.2	0.2	-0.3	0.3	0.3
Arm fat percentage (left)	0.1	0.3	0.9	-0.2	-0.4	-0.4	-1.0	-0.5	-0.4	-0.1	-0.4	-0.6	-0.6	-0.8
Loneliness, isolation	0.1	0.1	0.4	0.3	-0.4	-0.0	-0.0	0.6	0.2	-0.0	-0.4	-0.2	0.1	-0.0
Arm fat mass (left)	0.1	0.2	0.5	0.2	-0.7	-0.0	-0.7	0.1	0.1	0.7	-0.5	-0.7	-0.2	-0.4
Ever smoked	0.1	0.1	0.5	0.5	-0.0	0.3	-0.4	0.6	0.3	-0.2	-0.2	0.7	0.3	-0.2
Commuting to job workplace: Cycle	0.1	0.2	0.3	0.6	-0.1	0.2	0.5	0.5	0.3	0.4	0.5	-0.3	0.3	0.0
Basal cell carcinoma (self-reported)	0.1	0.1	0.4	0.0	-0.1	-0.3	-0.3	-0.1	-0.2	0.1	-0.6	-0.5	-0.5	-0.6
Heart disease (siblings)	0.1	0.2	0.5	0.1	-0.4	0.3	-0.0	0.7	0.2	-0.0	-0.4	0.3	0.5	0.7
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood White Count	0.0	0.3	2.0	-0.1	0.1	0.2	0.1	0.0	-0.1	-1.4	0.6	1.0	-0.2	0.1
BMI	0.0	0.2	0.4	0.3	-0.6	0.3	-0.7	0.3	0.4	-0.6	-0.4	0.2	0.1	0.1
Hair Pigment	0.0	0.4	1.5	0.2	0.4	-0.3	-0.5	-0.6	-0.3	-1.1	0.2	1.2	-0.4	-0.1
Tanning	0.0	0.4	1.5	0.7	-1.2	0.3	0.1	-0.0	0.8	0.7	-0.5	-0.4	0.3	0.9
Diabetes (mother)	0.0	0.0	0.1	0.2	-0.1	-0.2	-0.0	0.1	-0.3	0.3	-0.1	0.2	-0.3	-0.2
Body mass index (BMI)	0.0	0.1	0.2	0.5	0.0	0.3	-0.3	0.0	0.4	0.4	0.2	-0.0	0.2	0.2
Arm fat mass (right)	0.0	0.2	0.4	0.3	-0.6	0.1	-0.7	0.1	0.2	0.6	-0.4	-0.5	-0.1	-0.5
Leg fat percentage (right)	0.0	0.1	0.4	0.5	-0.5	0.2	-0.7	0.1	0.2	0.2	-0.1	0.3	-0.0	0.1
Leg fat mass (right)	0.0	0.2	0.8	0.3	-0.5	-0.1	-0.9	0.0	0.0	0.5	-0.4	-0.5	-0.3	-0.3
Smoking status: Current	0.0	0.1	0.4	0.0	0.3	-0.2	-0.1	0.4	-0.0	-0.1	0.0	-0.0	-0.1	-0.6
Leg fat percentage (left)	0.0	0.1	0.5	0.7	-0.3	0.3	-0.4	0.1	0.4	0.3	0.1	0.5	0.1	0.1
Leg fat mass (left)	0.0	0.2	0.6	0.5	-0.5	0.1	-0.8	0.1	0.3	0.7	-0.4	-0.4	-0.1	-0.2

Hub : Genes

WASF1

Models

Trait associations