TWAS hub - WDR35

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0950	0.0270	1.6e-05	0.084	0.046	0.067	0.071	0.076	2.0e-10	2.2e-06	1.4e-08	5.9e-09	1.6e-09
2	GTEx	Adipose Subcutaneous	0.1110	0.0390	7.6e-04	0.055	NA	0.063	NA	0.080	2.6e-05	NA	7.3e-06	NA	4.6e-07
3	GTEx	Artery Aorta	0.2540	0.0840	4.8e-03	-0.004	NA	0.009	NA	-0.004	7.0e-01	NA	9.3e-02	NA	6.6e-01
4	GTEx	Breast Mammary Tissue	0.2320	0.0600	2.9e-05	0.096	NA	0.066	NA	0.097	1.3e-05	NA	2.8e-04	NA	1.2e-05
5	GTEx	Breast Mammary Tissue (Male)	0.3162	0.1229	8.8e-03	0.105	NA	0.003	NA	0.064	2.1e-03	NA	2.8e-01	NA	1.4e-02
6	GTEx	Breast Mammary Tissue (Female)	0.3390	0.1030	4.4e-03	0.056	NA	-0.003	NA	0.022	8.9e-03	NA	3.9e-01	NA	7.4e-02
7	GTEx	Nerve Tibial	0.2199	0.0525	1.9e-06	0.049	NA	0.151	NA	0.114	2.0e-04	NA	7.6e-11	NA	1.9e-08
8	GTEx	Skin Not Sun Exposed Suprapubic	0.1420	0.0610	8.8e-03	0.095	NA	0.064	NA	0.090	6.7e-06	NA	2.1e-04	NA	1.2e-05
9	GTEx	Thyroid	0.1270	0.0470	6.4e-04	0.013	NA	0.029	NA	0.040	3.5e-02	NA	2.4e-03	NA	4.9e-04
10	METSIM	Adipose	0.0666	0.0204	1.4e-05	0.005	0.033	0.024	0.030	0.018	4.6e-02	1.0e-05	1.4e-04	2.1e-05	8.0e-04
11	TCGA	Prostate Adenocarcinoma	0.0881	0.0366	3.7e-04	0.079	0.028	0.060	NA	0.069	1.1e-08	5.7e-04	6.6e-07	NA	1.1e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Eye problems/disorders: Glaucoma	6.3	7.5	14.9	-3.1	-3.9	-2.4	-3.0	-1.8	-2.6	-3.7	-2.4	-3.5	-1.2	-0.0
Tinnitus: Yes, now most or all of the time	4.2	4.9	8.6	2.7	2.4	1.1	2.9	2.4	2.3	2.3	2.7	1.8	1.9	0.6
Medication: Levothyroxine sodium	4.1	6.9	12.5	-3.3	-1.9	-0.2	-3.3	-1.9	-3.5	-3.0	-2.6	-2.1	-3.1	-2.0
Qualifications: NVQ or HND or HNC or equivalent	4.1	4.9	8.9	3.0	2.4	1.0	2.8	2.1	2.9	1.5	2.9	1.9	1.6	-1.1
Glaucoma (self-reported)	3.5	4.1	10.6	-2.1	-2.9	-1.4	-2.1	-0.9	-1.7	-3.3	-1.8	-2.8	-1.0	-0.1
Supplements: Fish oil (including cod liver oil)	3.0	4.0	7.3	-1.8	-2.5	-2.2	-1.6	-1.6	-1.3	-2.7	-1.4	-2.6	-2.2	-1.5
Age at last live birth	2.9	4.2	7.5	-2.5	-2.7	-0.5	-2.4	-1.9	-2.0	-1.7	-1.9	-2.0	-2.7	-0.1
Mouth/teeth dental problems: Mouth ulcers	2.9	4.6	8.0	2.5	1.7	2.2	2.6	2.2	2.8	2.8	1.7	2.3	0.6	0.8
Illnesses of father: Heart disease	2.7	3.7	8.5	2.2	2.6	1.3	2.0	0.7	0.9	2.5	0.9	2.9	1.8	1.6
Mineral and other dietary supplements	2.7	3.6	7.8	1.7	2.5	1.7	1.5	1.1	1.2	2.3	0.9	2.5	2.8	1.4
Eye problems/disorders: None of the above	2.5	2.9	7.2	1.9	2.6	1.2	1.7	1.1	1.6	2.0	1.4	2.7	0.3	0.5
Qualifications: CSEs or equivalent	2.4	3.2	5.9	2.2	1.3	1.9	2.4	1.6	2.4	1.8	2.3	1.1	1.0	0.1
Number of full sisters	2.3	2.8	8.7	-2.1	-2.0	-1.2	-1.8	-2.0	-1.5	-1.0	-0.8	-1.1	-3.0	-0.0
Stomach or abdominal pain in last month	2.1	2.7	5.0	-2.2	-2.2	-0.8	-2.1	-1.7	-2.1	-0.6	-1.5	-1.1	-1.3	1.4
Angina	2.0	2.6	9.4	1.0	1.3	1.9	0.9	0.5	1.1	3.1	1.0	1.4	1.4	2.3
Pain all over the body in last month	2.0	2.2	3.9	-2.0	-0.9	0.4	-1.6	-1.7	-1.9	0.3	-1.8	-0.7	-1.8	1.8
Falls in the last year	2.0	2.7	7.0	-2.2	-1.1	-1.5	-2.0	-1.7	-1.7	-0.7	-1.4	-1.1	-2.6	-0.6
Angina (self-reported)	2.0	2.6	9.1	1.0	1.2	1.9	0.8	0.5	1.0	3.0	0.9	1.5	1.4	2.4
Commuting to job workplace: Walk	2.0	2.2	7.1	-1.2	-0.4	-1.3	-1.3	-2.4	-1.4	-1.6	-2.7	-0.2	-0.9	-0.8
Fractured/broken bones in last 5 years	2.0	2.6	4.5	-2.1	-1.9	-1.7	-1.9	-1.6	-1.5	-1.6	-1.2	-1.4	-1.7	-0.6
Rheumatoid Arthritis	1.9	2.6	6.0	-1.6	-1.3	-2.4	-1.4	-2.1	-1.5	-1.6	-2.0	-1.0	-1.2	-0.6
Health satisfaction	1.9	2.5	6.8	-1.6	-1.2	-1.3	-1.5	-2.3	-1.9	-0.6	-1.8	0.4	-2.6	0.3
Standing height	1.8	17.7	51.6	-0.1	-4.1	-5.8	-0.2	1.0	0.5	-6.3	0.2	-7.1	-0.2	-7.2
Pulse rate, automated reading	1.8	5.9	12.2	3.2	2.2	0.9	3.5	2.2	3.3	2.3	3.3	1.2	1.8	0.2
Comparative height size at age 10	1.8	9.7	27.9	-1.3	-3.1	-4.4	-1.1	0.2	-0.9	-5.2	-0.4	-4.1	-1.6	-5.3
Commuting to job workplace: Public transport	1.8	2.1	3.8	-2.0	-1.8	-0.8	-2.0	-1.5	-1.5	-1.2	-1.7	-1.2	-1.3	0.2
Height	1.7	32.0	110.2	-0.4	-5.2	-7.0	-0.1	1.1	0.4	-8.3	1.0	-10.5	-1.0	-9.7
Relative age of first facial hair	1.7	3.4	8.6	1.6	0.1	-0.4	1.9	2.9	1.9	-1.7	1.6	-2.4	0.4	-2.8
Taking other prescription medications	1.7	2.6	11.7	-1.7	-0.8	-0.8	-1.5	-0.9	-2.1	-1.7	-1.6	-0.3	-3.4	-0.5
High blood pressure (mother)	1.7	2.4	4.6	2.1	1.9	1.3	2.0	1.1	1.6	1.7	0.9	2.0	1.0	0.6
Hearing difficulty/problems with background noise	1.7	2.8	7.2	2.5	1.8	-0.4	2.4	1.2	2.7	0.8	1.8	1.0	0.1	-1.2
Mouth/teeth dental problems	1.7	2.7	5.5	-1.9	-1.8	-1.1	-1.8	-2.1	-2.4	-1.5	-1.7	-1.4	-1.0	0.3
Basal cell carcinoma (self-reported)	1.7	2.0	5.6	-1.1	-0.5	0.3	-1.5	-2.1	-1.6	0.4	-2.1	0.7	-0.8	2.4
Happiness	1.6	2.0	7.0	-0.9	-1.8	-1.0	-0.8	-1.8	-0.8	-1.3	-1.6	-0.1	-2.6	-1.0
Qualifications: A levels/AS levels or equivalent	1.6	3.6	8.6	-1.9	-2.0	-1.2	-2.2	-1.4	-1.7	-2.5	-2.9	-2.1	-1.3	-0.5
Neck or shoulder pain in last month	1.6	2.2	6.6	1.5	1.2	-0.9	1.4	2.6	1.2	0.6	2.3	1.8	0.3	-0.9
Medication: Co-codamol	1.5	1.8	4.1	-2.0	-0.8	0.7	-2.0	-0.6	-2.0	0.1	-0.8	0.4	-1.7	1.6
Tinnitus: Yes, but not now, but have in the past	1.5	1.6	3.7	-1.3	-1.9	-1.3	-1.4	-1.0	-1.2	-1.2	-0.7	-1.3	-1.1	-1.1
Father’s age at death	1.5	2.0	5.6	-0.9	-1.8	-0.5	-0.7	-0.6	-0.6	-2.3	-0.7	-2.4	-0.3	-2.2
Length of working week for main job	1.5	1.7	3.4	1.8	0.9	1.8	1.5	1.1	1.8	0.2	1.4	0.9	0.6	-1.2
Migraine (self-reported)	1.5	1.9	13.7	-0.4	-0.4	-1.6	-0.3	-0.6	-0.8	-1.5	-0.4	-0.2	-3.7	-0.6
Average weekly red wine intake	1.5	2.2	4.3	-1.2	-1.7	-1.4	-1.4	-1.4	-1.3	-1.7	-1.7	-2.1	-1.5	0.3
Reaction Time	1.4	2.6	5.2	-1.5	-0.7	-1.2	-1.4	-2.3	-1.8	-0.5	-2.1	0.5	-2.2	2.0
HbA1C	1.4	1.6	5.0	0.3	0.8	1.0	0.8	1.3	1.0	1.7	0.7	1.1	1.7	2.2
Exposure to tobacco smoke at home	1.4	1.5	3.6	1.9	1.1	-1.0	1.7	0.9	1.7	-0.1	1.4	0.5	-0.4	-1.4
Alzheimer’s Disease (including proxy)	1.3	1.9	7.5	1.2	1.9	1.0	1.2	1.2	0.7	1.4	0.4	1.3	2.7	0.1
Medication for hormone replacement therapy	1.3	1.4	8.7	0.4	-0.6	-1.2	0.8	1.1	0.6	-1.0	0.9	-0.9	0.3	-3.0
Multivitamins +/- minerals	1.3	1.7	6.9	-0.1	0.5	2.6	-0.1	1.1	-0.5	1.3	-0.2	1.4	-0.6	2.4
Ever highly irritable/argumentative for 2 days	1.3	1.5	5.8	1.3	0.2	-0.8	1.4	1.0	1.6	-0.7	1.4	0.0	-0.8	-2.4
Medication: Ventolin 100micrograms inhaler	1.3	1.7	3.3	-1.5	-0.9	-1.5	-1.8	-1.4	-1.7	-1.1	-1.6	-0.7	-0.9	0.0
Wears glasses or contact lenses	1.3	1.5	3.2	1.8	1.7	0.2	1.7	0.6	1.7	0.8	1.1	1.1	0.6	-0.8
Diastolic blood pressure, automated reading	1.3	3.9	7.9	2.3	2.8	1.7	2.3	0.5	1.7	2.8	1.7	1.6	1.7	1.5
Alzheimer’s Disease (in father)	1.2	1.3	3.5	1.6	1.9	0.6	1.6	0.3	1.2	0.7	0.2	1.2	1.1	-0.2
Major Depression (MDD)	1.2	1.5	4.5	1.1	1.4	1.9	1.5	0.6	0.7	0.8	-0.0	2.1	-1.0	0.3
Prostate Cancer	1.2	1.6	4.0	1.3	1.3	1.6	1.5	2.0	1.1	0.4	1.7	0.3	0.9	-0.9
Hypothyroidism (self reported)	1.2	2.7	5.9	-1.7	-0.7	-1.3	-1.8	-0.9	-1.8	-2.3	-1.2	-0.8	-2.4	-1.9
Lung FEV1/FVC ratio	1.2	6.0	11.6	2.8	2.1	-0.7	3.1	3.0	3.0	1.3	2.8	0.1	3.4	-2.0
Diverticular disease/diverticulitis (self-reported)	1.2	1.5	4.1	-1.3	-2.0	-1.9	-1.1	-0.7	-0.9	-1.2	-0.1	-1.7	-0.3	-0.0
Financial difficulties in last 2 years	1.2	1.6	4.1	-1.3	-1.6	-2.0	-1.4	-1.2	-0.8	-1.2	-0.5	-0.0	-2.0	-0.3
Loud music exposure frequency	1.2	1.3	4.1	-0.9	-1.6	1.1	0.0	1.3	-0.5	-0.8	0.6	-2.0	-1.2	-1.3
Mean time to correctly identify matches	1.2	2.2	5.6	-1.3	-0.4	-1.0	-1.2	-2.2	-1.6	-0.9	-2.0	0.4	-2.4	1.4
Supplements: Vitamin C	1.2	1.4	3.6	-1.5	-1.4	-1.9	-0.9	-0.8	-1.4	0.0	-0.9	-0.2	-1.8	0.9
Loneliness, isolation	1.2	1.6	6.0	-0.1	-0.5	-1.8	0.2	1.1	-0.1	-1.7	0.3	-1.1	-1.8	-2.5
Pain experienced in last month	1.2	1.9	5.5	1.5	0.6	-0.1	1.9	1.1	2.4	-0.2	0.6	-1.2	1.9	-1.7
Depression (self-reported)	1.1	1.3	2.7	-1.2	-1.4	-0.3	-1.2	-1.6	-0.8	-1.2	-1.3	-1.5	-0.8	-0.6
Medication: Lansoprazole	1.1	1.2	3.3	1.2	1.6	0.2	0.7	1.0	0.9	1.1	-0.2	1.4	1.8	0.7
Age at first live birth	1.1	2.0	5.7	-1.1	-2.0	-0.7	-1.3	-1.6	-0.6	-1.7	-1.2	-2.4	-0.7	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.2	9.4	0.2	-1.5	-1.5	0.2	0.9	0.6	-2.4	0.5	-1.7	-0.0	-3.1
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	2.8	-1.4	-1.6	0.5	-1.1	-0.6	-1.3	-0.0	-0.2	-1.7	-0.9	-1.2
Friendships satisfaction	1.1	1.3	2.7	-1.6	-1.1	-0.2	-1.4	-1.7	-1.5	-0.3	-1.4	0.5	-1.1	-0.1
Illnesses of father: High blood pressure	1.1	1.3	2.9	-1.0	-0.2	-1.4	-1.1	-1.5	-1.2	-0.7	-1.5	1.2	-1.7	-0.0
Average weekly beer plus cider intake	1.1	1.5	7.0	-0.3	0.8	1.4	-0.2	0.1	-0.5	1.9	0.2	2.6	-0.6	1.7
Medication: Omeprazole (e.g. Zanprol)	1.1	1.3	2.5	-1.2	-1.2	-0.0	-1.4	-1.5	-1.4	0.2	-0.7	-0.7	-1.6	1.5
Hand grip strength (left)	1.0	2.8	11.7	1.7	-0.7	0.9	1.6	1.2	1.7	0.8	2.2	-1.6	3.4	-0.1
Hair/balding pattern: Pattern 4	1.0	2.5	13.4	-0.1	1.3	-0.1	0.2	-0.5	-0.4	1.2	-1.0	3.7	-2.1	2.2
Hypothyroidism/myxoedema (self-reported)	1.0	1.9	5.5	-1.4	-0.2	-0.1	-1.5	-0.8	-1.8	-1.6	-0.9	-0.3	-2.3	-2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	3.1	-1.3	-0.2	1.1	-1.3	-0.8	-1.7	0.7	-0.9	0.5	-0.7	1.8
LDL Cholesterol	0.9	1.3	3.6	0.8	1.5	-0.1	0.8	0.2	1.1	1.9	0.5	0.6	1.7	1.7
Average weekly spirits intake	0.9	1.1	3.2	-1.6	-0.3	-0.1	-1.8	-0.9	-1.8	-0.5	-1.1	-0.3	0.6	0.4
Sensitivity / hurt feelings	0.9	1.6	4.0	-1.4	-0.8	0.1	-2.0	-1.1	-1.6	-0.6	-1.5	-0.8	-1.1	1.6
Severe depression (siblings)	0.9	1.1	3.5	-1.2	-0.6	0.9	-1.1	-1.2	-0.9	0.5	-1.9	-0.1	-0.5	1.2
Serious illness, injury or assault to yourself	0.9	1.0	3.4	-1.1	-0.8	-0.9	-0.9	-1.3	-1.2	0.5	-0.4	0.1	-0.8	1.8
Hair/balding pattern: Pattern 2	0.9	1.1	4.4	-0.3	-2.1	-0.5	-0.6	-1.2	0.2	-1.2	-0.7	-1.9	-0.6	-0.2
Worrier / anxious feelings	0.9	1.6	3.4	-1.6	-1.0	-0.4	-1.8	-1.3	-1.8	0.0	-1.7	-0.5	-1.1	1.3
Number of live births	0.9	1.2	3.2	-1.8	-0.5	-0.3	-1.8	-0.7	-1.6	-0.7	-1.6	-0.3	-0.9	-0.4
Illnesses of mother	0.9	1.2	2.1	-1.0	-1.0	-1.2	-1.2	-0.8	-1.1	-1.2	-1.4	0.2	-1.5	-0.2
Medication: Amlodipine	0.9	1.3	4.8	-0.4	1.0	-1.8	-0.3	-0.3	-0.5	-0.7	0.1	1.0	-2.2	-1.9
Heart disease (mother)	0.9	1.1	3.1	0.9	1.5	-0.7	1.3	1.4	1.0	0.4	1.8	-0.3	0.2	-0.5
Illnesses of father: None of the above (group 1)	0.9	1.2	2.8	-1.6	-1.6	1.4	-1.1	-0.3	-0.8	-0.3	-0.3	-1.7	-0.6	0.4
Hearing aid user	0.9	1.1	2.7	-1.1	-0.7	-0.8	-1.6	-1.6	-0.7	-0.1	-1.2	-1.4	-0.2	-0.3
Financial situation satisfaction	0.9	1.1	2.9	-0.7	-1.2	-1.7	-1.1	-1.5	0.0	-1.1	-1.1	-0.7	-0.2	-1.0
Fasting Glucose	0.8	1.0	2.0	-1.2	-0.4	1.3	-1.4	-1.0	-1.2	-0.6	-1.1	0.6	-1.0	0.6
Waist Hip Ratio (WHR)	0.8	3.6	14.1	1.7	0.0	-1.9	1.8	2.0	2.0	-0.4	1.8	-1.4	1.6	-3.8
Frequency of depressed mood in last 2 weeks	0.8	1.1	4.7	-1.1	-0.6	-1.1	-0.9	-1.1	-1.3	0.0	-0.9	0.0	-2.2	0.6
Supplements: Zinc	0.8	0.8	2.3	-0.4	-1.2	-1.0	-0.3	-1.0	-0.5	0.0	-0.7	0.0	-1.5	1.5
Age when periods started (menarche)	0.8	2.0	4.4	-1.3	-0.8	1.9	-1.6	-2.0	-1.3	-1.2	-2.1	-0.7	-1.3	0.3
Had other major operations	0.8	0.9	2.7	1.1	1.3	-1.1	1.1	0.0	0.3	0.9	0.9	1.6	-0.6	0.4
Alcohol intake versus 10 years previously	0.8	1.2	3.6	0.7	0.5	0.6	1.2	1.8	0.9	1.0	1.9	0.8	1.0	0.1
Pulse wave Arterial Stiffness index	0.8	0.9	4.4	0.5	-0.5	-1.0	0.4	0.7	0.7	-0.4	1.3	-0.6	-0.6	-2.1
Blood clot in the leg (DVT)	0.8	1.0	3.4	-1.3	-1.1	1.5	-1.1	-0.2	-1.0	-0.4	0.1	-1.8	-0.3	0.0
Number of full brothers	0.8	1.1	1.8	1.4	1.3	0.9	1.2	0.8	1.2	1.2	0.8	1.1	0.7	-0.2
Medication: Allopurinol	0.8	1.0	2.7	-1.1	-0.8	0.9	-1.1	-1.6	-1.2	0.3	-0.8	0.5	-1.3	0.7
Medication: Omeprazole	0.8	0.9	5.0	-0.6	-0.2	0.5	-0.7	-0.8	-0.8	1.4	0.3	0.6	-0.7	2.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	2.3	0.6	0.8	1.3	0.7	0.6	0.4	1.5	0.7	0.6	1.2	1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.7	5.8	-1.2	-0.1	0.8	-0.7	-1.6	-1.8	0.5	-2.0	0.7	-0.1	2.4
Medication: Lisinopril	0.8	1.1	5.4	0.7	1.6	2.3	0.7	0.9	0.7	0.4	0.1	-0.0	0.9	-1.1
Ever depressed for a whole week	0.8	1.0	4.8	0.3	0.3	-1.2	0.2	-1.1	0.4	-0.7	-1.1	0.5	-2.2	-1.4
Bipolar Disorder (2018)	0.7	1.1	3.2	1.3	0.2	0.7	1.4	1.8	1.3	-0.3	1.5	0.3	-0.1	-0.9
Age at First Birth	0.7	1.0	2.7	1.6	0.9	0.5	1.4	0.5	1.4	0.8	0.7	0.9	0.7	0.2
Blood Eosinophil Count	0.7	5.0	12.6	-2.7	-2.1	-0.1	-3.0	-3.5	-2.7	-1.4	-2.7	-0.5	-2.2	-0.1
Systolic blood pressure, automated reading	0.7	2.2	10.7	0.6	1.3	3.3	0.7	-0.1	0.4	2.6	0.5	1.0	-0.6	1.6
Average weekly fortified wine intake	0.7	0.8	2.1	-0.9	-1.0	-1.0	-1.0	-1.4	-0.7	-0.5	-0.7	-1.0	-0.2	0.4
Maternal smoking around birth	0.7	1.0	7.8	-0.3	-0.3	-1.0	-0.4	-0.6	-0.1	-1.2	-0.3	0.6	-2.8	0.2
Fed-up feelings	0.7	1.3	3.8	1.1	1.9	1.3	1.0	2.0	0.3	0.9	1.2	0.9	0.3	-0.2
Qualifications: None of the above	0.7	1.5	3.9	-1.8	-1.0	0.8	-1.4	-0.8	-1.6	-0.8	-1.4	-0.4	-2.0	-0.3
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	4.2	-0.5	1.0	0.1	-0.4	-0.4	-1.0	0.9	-0.5	2.1	-1.8	0.8
Mouth/teeth dental problems: Dentures	0.7	1.2	3.9	0.5	1.0	2.0	0.6	1.5	0.8	0.7	1.5	-0.5	0.9	-0.9
Trunk predicted mass	0.7	3.8	16.4	1.0	-0.9	-2.2	1.3	1.0	0.9	-1.8	1.6	-3.0	-0.1	-4.0
Had major operations	0.7	0.8	3.9	-0.9	-2.0	-0.4	-0.9	-0.4	-0.6	-0.5	-0.9	-1.2	-0.3	0.4
Leg pain on walking	0.7	0.8	4.1	-0.8	-0.1	-1.2	-0.7	-0.9	-0.9	-0.2	-1.0	0.2	-2.0	0.4
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	3.4	0.9	1.1	1.8	0.6	0.2	0.8	0.4	0.3	-0.1	1.7	-0.1
Supplements: Calcium	0.7	0.8	5.0	-0.6	-1.3	-2.2	-0.6	-0.3	-0.7	-0.5	-0.7	-0.3	-0.6	0.1
Deep venous thrombosis (DVT) (self-reported)	0.7	1.0	3.1	-1.2	-1.1	1.4	-1.1	-0.2	-1.1	-0.5	0.2	-1.8	-0.0	0.1
Crohns Disease (2017)	0.6	1.2	4.3	-0.0	-1.8	-1.4	-0.3	0.6	-0.1	-1.6	-0.4	-2.1	-0.0	-0.9
Body Mass Index (BMI) (2010)	0.6	0.8	3.0	-0.6	-1.7	-0.2	-0.4	-0.5	-0.4	-1.5	-0.5	-1.5	0.3	-0.8
Crohns Disease (2012)	0.6	1.0	2.3	-0.5	-1.4	-1.5	-0.9	-0.1	-0.4	-1.5	-0.5	-1.5	0.1	-0.7
Systolic Blood Pressure	0.6	2.9	14.1	0.8	1.8	3.8	0.8	-0.2	0.4	2.6	-0.1	1.6	-1.6	1.1
Number of treatments/medications taken	0.6	1.0	3.1	-1.1	-0.3	-0.6	-1.0	0.4	-1.3	-1.1	-0.3	-0.7	-1.3	-1.8
Hearing difficulty/problems: Yes	0.6	1.0	1.9	0.6	-0.2	-0.7	1.0	0.6	1.2	-0.9	1.0	-1.4	-1.3	-1.3
Diabetes (mother)	0.6	0.8	2.5	-1.5	-0.4	0.3	-0.9	-0.5	-1.5	-0.5	0.1	-0.6	-1.6	-0.4
Hand grip strength (right)	0.6	1.6	7.6	1.4	-0.6	0.9	1.2	0.7	1.1	0.5	1.2	-1.5	2.8	0.2
Townsend deprivation index at recruitment	0.6	0.9	4.0	0.1	-0.6	-0.6	0.3	1.2	0.6	-0.3	1.4	0.2	-2.0	-1.1
Current tobacco smoking	0.6	0.9	2.6	0.9	1.1	1.6	0.9	0.9	1.0	1.0	0.4	1.4	-0.3	-0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	6.1	-1.2	-0.8	1.9	-0.8	-0.9	-1.1	-0.7	-0.9	-0.6	-2.5	0.3
Ever unenthusiastic/disinterested for a whole week	0.6	0.8	2.2	-0.7	0.3	-0.8	-0.4	-0.9	-0.5	-0.7	-1.1	0.8	-1.5	-1.2
Trunk fat-free mass	0.6	3.7	15.7	1.0	-1.0	-2.2	1.2	0.9	0.9	-1.8	1.6	-3.0	-0.1	-4.0
Medication: Cholesterol lowering	0.6	0.9	2.0	0.6	1.3	0.8	0.8	1.4	0.0	0.9	0.6	0.7	1.4	0.5
Impedance of arm (left)	0.6	3.0	8.9	-1.5	-2.1	-1.8	-2.1	-0.6	-0.8	-3.0	-2.3	-1.6	-0.3	-0.7
Peak expiratory flow (PEF)	0.6	1.3	5.6	-0.4	-0.5	-0.5	-0.4	-1.3	-0.5	1.9	-0.5	-0.1	1.4	2.4
Pulse wave reflection index	0.6	0.7	2.0	-0.6	-1.4	-0.3	-0.5	0.5	-0.3	-1.0	0.1	-0.6	-1.2	-1.4
Birth weight	0.6	1.3	3.6	0.0	1.6	-1.9	-0.1	-0.3	-0.6	1.6	0.4	1.2	1.2	1.4
High blood pressure (siblings)	0.6	0.9	2.8	0.7	1.7	-0.6	0.6	0.0	0.1	0.9	0.4	1.6	-0.6	1.2
Comparative body size at age 10	0.6	1.7	4.8	0.0	1.0	2.2	0.0	0.3	-0.6	2.0	0.7	0.5	1.8	2.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.7	2.9	-0.7	-1.6	-0.8	-0.3	-0.1	-0.4	-0.7	-0.7	-0.4	-1.7	-0.4
Wheeze or whistling in the chest in last year	0.6	1.1	2.8	-1.0	-0.2	-0.4	-1.1	-1.4	-0.8	-0.6	-1.7	-0.0	-1.7	-0.7
Commuting to job workplace: Car/motor vehicle	0.6	0.7	3.0	0.4	-0.6	1.7	-0.0	0.2	0.6	0.9	0.8	0.2	0.6	1.2
Illnesses of siblings: Diabetes	0.6	0.8	2.6	-0.6	-0.5	-0.8	-0.6	0.3	-0.5	-1.6	0.2	-0.8	-1.5	-1.1
Ever taken oral contraceptive pill	0.6	0.6	1.8	0.8	0.2	1.1	0.8	1.3	0.9	0.7	0.7	0.4	0.5	-0.4
Arm fat-free mass (left)	0.6	2.8	13.3	0.7	-0.7	-1.9	0.8	1.0	0.5	-1.7	1.4	-2.5	0.0	-3.6
Cholesterol lowering medication	0.6	0.9	1.9	1.0	1.1	-1.1	0.7	0.9	0.8	0.3	1.2	-0.5	0.7	-1.4
Schizophrenia vs Biploar Disorder	0.5	0.6	2.8	0.3	1.7	-0.7	0.0	0.3	-0.0	1.1	0.3	1.4	-0.1	0.4
Alzheimer’s Disease (in mother)	0.5	0.6	3.6	-0.8	0.0	0.0	-0.8	-0.2	-0.9	0.5	-0.4	-0.2	1.9	0.6
Mean Putamen Volume	0.5	0.6	2.1	-0.8	-0.5	0.4	-0.4	-1.4	-0.7	1.1	-0.6	-0.2	0.9	0.5
Triglycerides	0.5	0.7	2.6	0.6	0.6	-1.6	0.9	0.6	0.9	0.5	1.4	0.6	0.4	-0.1
Lung FVC	0.5	2.3	8.0	0.7	1.6	0.4	1.0	-0.6	-0.1	2.5	-0.8	1.9	1.4	2.8
Chronotype (morning person)	0.5	1.2	3.4	1.5	-0.0	-0.5	1.5	1.9	0.9	0.3	1.6	0.1	1.3	-0.1
Ever had hysterectomy (womb removed)	0.5	0.6	2.5	-0.2	-0.8	0.9	-0.5	-0.4	-0.7	0.6	-0.3	0.6	-0.7	1.6
Vitamin and mineral supplements	0.5	0.7	2.5	0.1	0.3	-0.9	-0.2	-1.1	0.3	-1.2	-0.0	-1.1	0.4	-1.6
Impedance of leg (right)	0.5	2.2	6.9	-0.7	-2.0	-1.2	-1.1	-0.2	0.2	-2.6	-1.3	-2.6	0.2	-1.3
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	3.4	0.7	0.6	-0.1	0.5	1.0	0.3	0.4	0.3	1.0	1.8	0.2
Chronic bronchitis/emphysema (father)	0.5	0.6	2.3	0.1	-0.0	-1.3	-0.0	0.6	0.5	-0.7	0.2	-0.1	1.3	-1.5
Nervous feelings	0.5	0.9	2.9	0.3	1.3	-0.1	0.3	0.6	0.1	1.6	0.4	1.7	-0.1	1.5
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	3.0	0.0	-0.0	0.1	0.5	0.5	-0.3	-1.1	0.1	-1.7	-0.9	-1.3
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	3.2	0.6	0.7	-1.3	0.5	0.4	0.5	0.8	0.2	1.8	0.5	0.6
Medication: Paracetamol	0.5	0.8	3.7	-0.9	-0.5	0.6	-0.9	-0.7	-0.7	-0.0	-0.5	0.8	-1.9	0.8
Headache pain in last month	0.5	0.9	4.7	-0.4	0.2	-0.3	-0.8	0.3	-1.0	0.2	-0.5	2.2	-0.8	1.5
Gout (self-reported)	0.5	0.8	2.3	0.9	0.7	0.6	0.9	-0.0	0.7	1.5	1.2	0.9	0.7	0.6
Arm fat-free mass (right)	0.5	2.4	11.3	0.9	-0.2	-1.8	1.1	1.0	0.7	-1.2	1.5	-2.1	0.4	-3.4
Pulse wave peak to peak time	0.5	0.6	2.0	-0.6	-0.0	0.5	-0.6	-0.6	-0.8	-0.4	-1.4	-0.3	0.5	1.3
Shortness of breath walking on level ground	0.5	0.6	1.8	-0.5	-0.1	1.4	-0.4	-0.9	-0.5	0.5	-0.9	1.0	-0.0	1.2
Medication: Ibuprofen	0.5	0.6	1.1	-0.8	-1.1	-0.6	-0.8	-0.5	-0.5	-0.8	-0.0	-1.1	-0.7	-1.0
Arm predicted mass (right)	0.5	2.6	12.5	0.7	-0.5	-2.1	0.9	0.8	0.5	-1.4	1.4	-2.2	0.1	-3.5
Knee pain experienced in last month	0.5	0.8	5.6	-0.8	-0.5	0.5	-0.5	-0.5	-0.5	-0.4	-0.4	0.7	-2.4	-0.2
Whole body fat-free mass	0.5	2.7	12.5	0.8	-0.6	-2.0	1.0	1.0	0.6	-1.4	1.5	-2.2	0.1	-3.5
Long-standing illness, disability or infirmity	0.5	0.8	3.0	-1.0	-0.7	-0.5	-0.8	-0.4	-0.8	-0.6	-0.3	-0.7	-1.7	-1.3
Guilty feelings	0.5	0.7	2.0	0.8	1.1	-0.7	0.7	1.4	0.8	0.8	0.9	1.1	-0.1	-0.1
High cholesterol (Self-reported)	0.5	0.9	2.1	0.5	0.9	-0.2	0.7	1.4	0.3	0.3	1.4	-0.8	1.5	-1.2
Medication: Bendroflumethiazide	0.5	0.8	2.0	-0.7	0.7	0.3	-0.5	-0.4	-1.2	-1.3	-0.8	0.9	-1.4	-0.7
Myopia	0.5	0.7	1.5	0.6	0.0	0.6	0.7	0.7	1.1	0.8	1.2	-0.1	1.1	1.1
Heart attack/myocardial infarction (self-reported)	0.5	0.7	2.7	-0.2	0.2	1.2	-0.5	0.2	-0.2	0.9	-0.3	0.1	1.6	1.3
Impedance of whole body	0.5	2.6	8.4	-1.1	-2.1	-1.6	-1.7	-0.2	-0.3	-2.9	-1.9	-2.2	0.2	-0.9
Depressed Affect (Nagel 2018)	0.4	0.8	2.7	-0.4	0.7	-0.4	-0.2	0.7	-1.0	-1.0	-0.2	0.2	-1.6	-1.7
Depression (Nagel 2018)	0.4	0.5	2.7	-0.7	0.1	0.2	-0.7	-0.1	-1.2	-0.1	-0.5	0.6	-1.6	-0.1
Neuroticism (Nagel 2018)	0.4	1.0	3.3	-1.0	0.4	-0.5	-1.2	0.3	-1.8	-1.0	-1.0	-0.1	-1.5	-0.6
Coronary Artery Disease (CAD)	0.4	0.5	1.2	-0.2	0.7	0.6	-0.4	0.8	-0.7	-0.3	0.5	-1.1	0.6	-1.0
HDL Cholesterol	0.4	0.7	4.2	-0.2	1.3	0.3	-0.0	0.3	-0.5	1.0	-0.5	0.2	2.0	0.5
Neuroticism	0.4	0.9	2.3	-1.0	-0.3	-1.1	-1.2	0.2	-1.4	-0.5	-1.0	-0.2	-1.5	-0.3
Medication: Atenolol	0.4	0.4	1.3	-0.5	-0.9	-0.2	-0.3	-0.1	-0.7	-0.8	-0.7	-0.8	0.4	-1.1
Body mass index (BMI)	0.4	1.9	4.2	0.8	2.0	1.8	1.0	1.0	0.5	2.1	1.4	2.0	0.5	0.2
Impedance of leg (left)	0.4	1.8	6.1	-0.4	-1.7	-1.2	-0.7	0.3	0.5	-2.3	-1.0	-2.5	0.4	-1.4
Medication: Ramipril	0.4	0.6	2.3	-0.1	0.3	-0.1	-0.3	-0.8	-0.7	0.4	-0.7	1.2	-1.5	0.9
Medication: Simvastatin	0.4	0.5	2.1	-0.1	0.9	0.6	-0.0	0.9	-0.4	0.5	0.8	-0.8	1.4	-0.4
Illnesses of siblings	0.4	0.6	2.0	0.1	-0.8	-0.0	0.1	0.3	0.7	-0.5	-0.2	-1.4	1.4	-1.2
Impedance of arm (right)	0.4	1.9	6.7	-1.1	-1.9	-1.4	-1.6	0.1	-0.4	-2.6	-1.9	-1.0	-0.0	-0.5
Pulse rate	0.4	0.7	1.6	1.1	0.5	-0.4	1.3	0.5	1.3	0.5	1.0	0.6	0.8	-0.4
Asthma	0.4	0.8	4.0	-0.5	0.3	-0.4	-0.6	-1.4	-0.7	0.1	-0.7	0.7	-2.0	0.4
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.6	2.0	-0.4	-1.1	-0.2	-0.2	-0.0	0.1	-0.6	0.5	-1.3	-0.7	-1.4
Lung cancer (father)	0.4	0.5	1.9	-0.4	0.9	0.6	-0.4	0.2	-0.3	-0.3	-0.2	-1.1	-0.7	-1.4
Breastfed as a baby	0.4	0.4	1.4	-0.4	0.3	-0.1	-0.3	-1.2	-0.2	-1.1	-0.9	-0.4	-0.5	-0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	4.2	-0.2	-0.5	-0.2	-0.1	-0.3	-0.2	0.6	-0.5	1.0	-2.0	0.5
Medication: Seretide 50 evohaler	0.4	0.5	2.5	0.3	0.2	0.1	-0.1	-0.4	0.1	0.9	0.2	1.6	0.0	1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	2.5	0.3	-0.5	1.6	0.5	0.4	0.6	0.6	1.1	0.4	0.0	0.5
Alcohol intake frequency.	0.4	1.0	4.4	0.5	1.3	-0.4	0.8	2.1	0.6	0.3	1.6	0.6	0.7	-0.1
Overall health rating	0.4	0.8	2.8	-0.8	0.2	0.8	-0.7	-0.3	-1.1	0.8	-0.8	1.7	-1.2	0.8
Family relationship satisfaction	0.4	0.5	1.5	-0.6	-1.2	0.8	-0.2	-0.8	-0.2	0.2	-0.5	-0.7	-0.8	-0.7
Medication for cholesterol	0.4	0.6	5.0	-0.5	-0.2	0.1	-0.5	-0.3	-0.6	0.1	-0.6	0.6	-0.2	2.2
Back pain experienced in last month	0.4	0.6	1.6	-1.1	-0.7	-0.7	-1.3	-0.3	-1.3	0.0	-0.2	-1.0	0.2	0.5
Breast cancer (self-reported)	0.4	0.5	1.7	0.8	-0.2	-1.3	0.7	0.3	0.5	-0.7	0.7	-0.1	-0.8	-0.5
Medication: Aspirin	0.4	0.5	2.2	0.1	0.7	0.9	-0.0	1.1	0.0	-0.2	0.0	0.3	0.5	-1.5
Whole body water mass	0.4	2.4	11.3	0.8	-0.6	-2.0	1.0	0.9	0.6	-1.4	1.4	-2.1	0.1	-3.4
Miserableness	0.4	0.7	2.8	-0.4	-0.1	-1.0	-0.6	-0.7	-0.7	-0.4	-1.2	0.5	-1.7	-0.5
Mother’s age at death	0.4	0.5	1.2	-0.3	-0.4	-1.0	-0.3	-0.6	-0.7	-1.1	-0.6	0.0	1.0	0.4
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.8	-1.0	-0.4	-0.0	-1.1	-0.5	-1.3	-0.2	0.1	0.4	-0.9	0.5
Medication: Paracetamol	0.4	0.6	2.9	-0.8	-0.4	0.4	-0.9	-0.8	-0.5	-0.5	-0.9	0.2	-1.7	0.1
Basal metabolic rate	0.4	2.3	11.6	0.7	-0.6	-1.7	0.8	1.0	0.6	-1.4	1.4	-2.1	0.1	-3.4
Leg fat percentage (left)	0.4	1.4	3.1	0.7	1.4	1.8	0.8	1.3	0.8	1.3	1.4	0.8	1.2	-0.5
Number of operations (self-reported)	0.4	0.6	1.9	-0.1	-0.0	-0.6	-0.1	-0.7	-0.3	1.3	-0.2	0.9	-1.0	1.4
Risk taking	0.4	0.6	2.7	0.1	-0.8	1.1	0.5	0.4	0.8	0.7	1.7	-0.7	-0.1	-0.1
Ever had prostate specific antigen (PSA) test	0.4	0.4	1.7	-0.7	-0.4	-0.0	-0.3	-0.6	-0.5	-0.7	-0.4	-0.8	-1.3	-0.7
Heart disease (siblings)	0.4	0.5	2.0	0.2	-0.4	0.3	0.4	1.3	0.5	0.7	1.4	-0.1	-0.0	0.0
Arm predicted mass (left)	0.4	2.1	10.4	0.9	-0.3	-1.6	1.0	0.9	0.7	-1.2	1.4	-2.0	0.1	-3.2
Bipolar Disorder or Schizophrenia	0.3	0.7	3.5	0.5	0.5	1.0	0.6	1.9	0.5	0.1	1.1	0.1	0.3	-0.9
Irritable Bowel Disease (IBD)	0.3	0.8	3.0	0.6	-1.1	-1.2	0.7	1.0	0.6	-0.8	0.5	-1.7	0.2	-0.6
Ovarian Cancer	0.3	0.4	1.2	-0.2	-0.9	-1.1	-0.3	-0.3	-0.4	-0.6	-0.7	-0.5	-0.9	0.2
Bipolar Disorder (2011)	0.3	0.3	1.0	-0.9	-0.7	-0.1	-0.6	0.3	-0.8	-0.6	0.1	-0.0	-1.0	-0.1
Ulcerative Colitis	0.3	0.4	3.3	0.2	-0.5	-1.8	0.5	-0.1	0.5	-0.2	0.2	-0.6	0.1	-0.0
Respiratory disease	0.3	0.6	1.5	-0.4	0.6	0.3	-0.7	-1.2	-0.6	0.5	-0.6	1.1	-1.1	1.0
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.0	0.6	1.0	-0.7	0.6	0.8	0.2	-0.5	0.1	0.4	0.3	-0.8
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.1	-0.5	0.1	0.4	-0.4	-0.1	-0.2	0.1	0.4	-0.8	1.1	-0.7
Diabetes (father)	0.3	0.4	2.6	-0.2	0.5	-0.1	-0.4	-0.2	-0.5	0.0	0.2	1.1	-1.6	0.2
Leg fat-free mass (left)	0.3	1.5	7.3	0.5	-0.4	-1.8	0.6	0.9	0.2	-1.1	1.2	-1.2	0.3	-2.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	2.1	-0.2	0.1	0.6	-0.1	0.0	-0.6	0.7	0.2	0.6	-1.4	0.6
Relative age voice broke	0.3	0.5	1.8	0.1	-1.2	-0.3	0.5	0.8	0.3	-1.0	0.2	-1.3	-0.3	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	2.6	-0.7	-0.4	1.6	-0.4	-0.3	-0.9	-0.5	-0.5	-0.1	-1.3	-0.0
High blood pressure	0.3	0.7	2.3	-0.6	0.8	0.0	-0.5	-1.1	-0.9	-0.1	-1.5	1.1	-1.0	-0.5
Hayfever, allergic rhinitis or eczema	0.3	0.6	2.4	0.2	-0.7	-1.3	0.2	-0.1	-0.1	-0.5	-0.3	-0.5	-1.6	-0.9
Supplements: Glucosamine	0.3	0.3	0.8	0.6	-0.2	0.2	0.5	0.7	0.8	0.2	0.6	-0.9	-0.3	-0.8
Leg predicted mass (left)	0.3	1.6	7.6	0.5	-0.3	-1.8	0.6	0.9	0.2	-1.1	1.3	-1.3	0.3	-2.8
Waist circumference	0.3	1.1	4.1	1.0	1.0	-0.0	1.2	1.1	1.0	0.5	1.4	0.4	-0.0	-2.0
Number of incorrect matches in round	0.3	0.5	1.7	0.1	1.0	0.4	0.1	0.9	-0.3	-0.2	0.1	0.8	-1.3	-0.9
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	2.1	-0.2	0.4	-0.5	-0.3	-0.3	-0.7	0.8	-0.2	1.5	-0.8	0.9
Had menopause	0.3	0.3	1.4	0.3	0.8	0.5	0.4	1.2	0.3	-0.1	0.5	0.5	0.3	-0.6
Forced vital capacity (FVC)	0.3	1.3	4.7	-0.6	-1.4	-2.2	-0.5	-0.8	-0.6	-1.0	-1.0	-1.7	0.9	-0.4
Heart attack	0.3	0.4	1.8	-0.3	-0.0	0.8	-0.6	0.1	-0.3	0.5	-0.5	-0.1	1.4	1.0
Diabetes (self-reported)	0.3	0.4	1.6	0.1	-0.5	-0.3	0.3	0.7	0.7	-0.1	0.6	-0.6	1.3	-0.7
Weight	0.3	1.6	8.7	0.7	0.1	-0.8	0.8	1.4	0.7	-0.8	1.4	-1.2	0.4	-3.0
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	3.2	0.1	-1.0	-1.8	0.3	-0.3	0.0	-0.3	-0.2	-1.8	1.6	-0.5
Prospective memory result	0.3	0.3	1.5	-0.2	0.2	-0.4	-0.4	-0.5	-0.4	-0.1	0.0	1.2	-1.2	0.3
Medication for cholesterol, blood pressure or diabetes	0.3	0.6	2.0	-0.4	-1.3	-0.1	-0.8	-1.4	0.0	-0.4	-0.7	-0.4	-0.9	0.4
Chronic bronchitis/emphysema (mother)	0.3	0.3	0.8	0.4	-0.3	-0.2	0.4	-0.3	0.8	0.6	0.5	0.8	-0.9	0.6
Exposure to tobacco smoke outside home	0.3	0.4	1.2	-0.4	-0.6	0.0	-0.8	-0.9	-0.1	0.5	-0.7	0.1	-1.1	0.5
Worry too long after embarrassment	0.3	0.4	1.4	-0.7	0.1	-0.4	-0.6	-0.0	-1.2	0.2	-0.8	0.8	-0.1	1.0
Number of children fathered	0.3	0.3	0.7	-0.2	-0.8	-0.8	-0.4	-0.6	-0.2	-0.6	-0.6	-0.4	0.4	0.5
Emphysema/chronic bronchitis	0.3	0.4	1.2	0.5	-0.2	-0.5	0.3	0.4	0.7	-0.4	0.1	-0.9	0.9	-1.1
Suffer from ‘nerves’	0.3	0.5	1.0	0.8	0.5	0.4	0.6	0.8	0.6	1.0	0.9	0.9	0.1	0.1
Chest pain or discomfort	0.3	0.5	2.4	0.7	0.9	-0.7	0.5	0.3	0.2	0.4	-0.0	1.5	0.5	-0.2
Medication: Aspirin	0.3	0.4	1.7	-0.6	0.5	0.7	-0.7	0.4	-0.8	-0.6	-0.5	0.1	0.2	-1.3
Leg fat-free mass (right)	0.3	1.4	7.2	0.6	-0.3	-1.6	0.6	0.9	0.3	-0.9	1.3	-1.2	0.1	-2.7
Diabetes diagnosed by doctor	0.3	0.4	1.3	-0.3	-0.5	0.2	0.1	1.0	0.3	-0.3	0.6	-1.0	1.2	-0.8
Qualifications: nursing, teaching	0.3	0.5	1.3	-0.3	0.5	-1.2	-0.4	-0.3	-0.6	0.3	-0.5	1.0	0.4	1.1
Asthma (self-reported)	0.3	0.7	3.6	-0.4	0.6	-0.4	-0.5	-1.2	-0.6	0.2	-0.4	0.8	-1.9	0.2
Medication: Gliclazide	0.3	0.4	1.1	-0.7	-0.4	-0.5	-0.5	-0.6	-0.6	-1.0	-0.7	-0.7	-0.1	0.2
Smoking status: Current	0.3	0.5	1.1	0.7	0.5	1.1	0.7	0.8	0.9	0.6	0.2	0.8	-0.3	-0.3
Leg predicted mass (right)	0.3	1.5	7.5	0.7	-0.3	-1.7	0.7	1.0	0.3	-0.9	1.3	-1.2	0.2	-2.7
Medication: Blood pressure	0.3	0.6	2.0	-0.7	0.6	0.1	-0.7	-0.7	-1.1	0.1	-1.2	0.5	-1.4	-0.5
Medication: Atorvastatin	0.3	0.3	1.4	-0.1	0.2	-1.2	-0.4	0.4	-0.6	-0.8	-0.4	-0.5	-0.5	-0.6
Ever smoked	0.3	0.5	1.4	0.3	-0.9	0.0	0.5	0.3	0.7	0.2	1.0	0.0	-0.9	-1.2
Age started oral contraceptive pill	0.3	0.4	1.2	-0.7	-0.1	0.1	-0.3	0.7	-0.5	-1.0	0.1	-1.1	-0.2	-0.5
Unable to work because of sickness or disability	0.3	0.4	1.6	-0.0	0.2	-0.3	0.2	0.3	-0.0	1.2	0.8	1.3	-0.4	0.1
Commuting to job workplace: Cycle	0.3	0.4	1.3	-0.3	-0.1	1.0	-0.3	-0.4	-0.4	0.7	-0.3	0.5	-1.1	0.6
Vascular/heart problems diagnosed by doctor	0.3	0.8	2.1	0.6	-1.1	-0.6	0.6	1.0	1.0	-0.4	1.4	-1.2	0.6	0.1
Alcohol drinker status: Previous	0.3	0.3	1.3	-0.6	0.3	-1.1	-0.5	0.0	-0.5	0.1	-0.1	0.8	-0.4	0.8
Leg fat mass (left)	0.3	1.0	2.9	0.7	0.8	0.3	0.9	1.5	0.8	0.3	1.4	-0.0	1.1	-1.7
Intelligence (Savage-Jansen 2018)	0.2	0.6	2.2	1.1	0.6	-0.3	1.1	0.7	0.9	0.2	0.2	1.5	0.6	-0.3
Worry (Nagel 2018)	0.2	0.5	2.2	-0.8	0.5	-0.5	-1.1	0.2	-1.5	0.0	-0.4	0.2	-0.9	0.1
Ulcerative Colitis (UC)	0.2	0.4	1.2	0.3	-0.4	-1.0	0.7	0.8	0.1	-0.2	0.5	-1.1	-0.0	-0.0
Verbal and Numeric Reasoning (VNR)	0.2	0.6	1.4	0.8	0.6	0.3	0.8	1.1	0.2	0.7	-0.2	1.2	1.0	0.7
Lupus	0.2	0.3	1.3	-0.1	-0.4	0.5	-0.2	0.0	-0.2	1.1	0.6	0.8	0.4	0.8
Schizophrenia (2014)	0.2	0.4	1.0	-0.1	1.0	0.2	-0.2	0.9	-0.4	0.8	0.8	0.7	-0.3	0.3
Type 2 Diabetes (T2D) (2012)	0.2	0.3	0.8	-0.6	-0.4	0.8	-0.1	0.4	0.3	-0.1	0.8	-0.9	-0.3	-0.3
Blood White Count	0.2	1.3	4.6	-1.3	-0.1	-0.7	-1.3	-0.2	-2.1	-0.8	-0.8	-0.5	-0.2	-2.1
Heel T-Score	0.2	1.6	4.5	1.3	2.1	1.3	1.4	1.2	1.3	0.1	0.4	1.0	-2.0	-0.1
Smoking Status	0.2	0.6	1.7	0.8	-0.2	0.9	0.7	0.6	1.1	0.1	0.6	-0.1	0.9	-1.3
Cardiovascular Disease	0.2	0.5	2.2	-0.5	0.0	-0.2	-0.4	-1.0	-0.5	-0.5	-1.5	-0.8	0.4	-0.8
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.1	-1.1	-0.8	0.4	-0.8	-0.3	-0.9	-0.2	-0.8	-0.3	0.3	0.3
Medication: Metformin	0.2	0.3	1.1	-0.1	0.3	0.4	0.3	1.1	0.1	0.5	0.6	0.6	0.4	0.5
Pack years adult smoking proportion	0.2	0.2	0.9	0.0	-0.0	-0.4	-0.2	-0.5	0.5	0.9	0.2	0.4	0.3	1.0
Sitting height	0.2	1.6	8.7	-0.1	-0.5	-3.0	-0.5	0.1	-0.5	-0.8	-0.3	-1.2	2.2	-1.0
Allergy	0.2	0.6	3.1	-0.1	0.7	1.1	0.1	0.3	0.2	0.3	0.0	1.0	1.8	0.5
Fluid intelligence score	0.2	0.3	1.3	0.5	0.5	0.1	0.5	0.6	-0.1	0.2	-0.7	0.8	1.1	0.2
Arm fat percentage (right)	0.2	0.6	2.2	0.1	0.9	1.4	0.1	0.9	0.2	0.9	0.4	1.5	0.5	0.0
Hair/balding pattern: Pattern 3	0.2	0.3	1.4	-0.4	0.4	1.2	-0.2	-0.3	-0.1	0.7	0.2	0.5	-0.8	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.8	0.2	-0.3	-0.9	0.1	0.4	0.1	0.2	-0.5	0.8	0.2	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.8	2.3	0.4	-0.6	-1.3	0.5	0.4	0.2	-0.5	-0.1	-1.5	1.5	-1.0
Birth weight of first child	0.2	0.4	1.2	0.3	-0.1	1.0	0.2	-0.4	0.3	0.6	0.9	-0.5	0.2	1.1
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.7	0.7	-0.0	-0.6	0.6	0.4	0.8	0.4	0.4	-0.7	0.7	0.1
Forced vital capacity (FVC), Best measure	0.2	0.9	2.8	-0.2	-1.0	-1.5	-0.2	-0.3	-0.2	-1.1	-0.8	-1.7	1.0	-0.8
Leg fat percentage (right)	0.2	0.8	2.7	0.4	1.1	1.6	0.5	1.1	0.5	0.9	1.1	0.7	0.8	-0.5
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.6	0.4	0.8	0.1	0.6	0.5	0.1	0.0	0.5	0.4	0.2	-0.4
Medication for pain relief, constipation, heartburn	0.2	0.4	1.7	0.6	-0.4	-0.6	0.6	0.4	0.5	-0.3	-0.2	-0.8	1.3	-0.2
Medication: Blood pressure	0.2	0.4	1.1	-0.7	0.7	-0.0	-0.4	-0.2	-1.0	-0.6	-0.9	0.7	-0.1	-0.8
Whole body fat mass	0.2	0.7	4.2	0.3	0.3	-0.3	0.3	1.1	0.4	-0.4	0.7	-0.3	0.8	-2.0
Leg fat mass (right)	0.2	0.9	2.9	0.7	0.7	0.2	0.8	1.4	0.7	0.1	1.3	-0.1	1.0	-1.7
Hypertension (Self-reported)	0.2	0.6	1.9	-0.3	1.1	0.4	-0.3	-0.8	-0.7	0.3	-1.2	1.4	-0.7	-0.2
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.6	0.3	-0.2	-0.5	0.5	0.2	0.6	-0.3	0.8	-0.1	-0.3	-0.4
Mood swings	0.2	0.3	1.1	0.1	0.9	0.0	0.1	0.0	-0.3	0.2	-0.5	1.0	-1.0	0.0
Ever had bowel cancer screening	0.2	0.2	0.9	-0.4	-0.2	0.8	-0.6	-0.3	-0.2	-0.2	0.0	-0.6	-0.2	0.9
Eye problems/disorders: Cataract	0.2	0.2	1.4	-0.1	-0.5	0.1	-0.0	0.1	-0.1	-0.0	0.1	-0.8	1.2	0.0
Osteoarthritis (self-reported)	0.2	0.2	0.8	-0.1	-0.5	0.9	0.1	0.1	0.4	-0.2	0.1	-0.1	-0.5	-0.8
Number of self-reported non-cancer illnesses	0.2	0.4	1.2	0.2	1.0	0.7	0.7	1.1	-0.4	0.4	0.3	0.3	-0.5	-0.4
Average weekly champagne plus white wine intake	0.2	0.3	1.0	0.5	0.1	1.0	0.2	-0.3	0.7	0.1	-0.4	0.7	0.3	0.8
Alcohol drinker status: Never	0.2	0.3	1.2	-0.1	0.2	-0.1	-0.3	0.9	-0.0	0.0	-0.4	-0.5	1.1	-0.5
Pack years of smoking	0.2	0.3	1.2	-0.2	-0.1	-0.2	-0.5	-0.6	0.2	0.8	0.0	0.1	0.5	1.1
Schizophrenia (2018)	0.1	0.3	0.9	-0.4	0.6	0.8	-0.4	1.0	-0.3	0.4	0.2	-0.2	0.4	-0.4
Breast Cancer	0.1	0.2	1.0	-0.6	-0.5	0.1	-0.4	-1.0	-0.5	0.4	-0.5	-0.4	-0.3	0.0
Neuroticism (2016)	0.1	0.1	0.6	-0.4	0.4	-0.2	-0.3	0.2	-0.8	0.1	0.1	0.1	-0.3	-0.3
Primary Biliary Cirrhosis	0.1	0.2	0.8	0.1	-0.3	-0.5	-0.1	-0.1	0.3	-0.4	0.1	-0.9	0.4	-0.5
Blood Platelet Count	0.1	1.4	4.1	0.4	1.5	1.5	0.1	1.1	-0.0	2.0	0.7	1.3	1.2	1.4
Blood Red Count	0.1	1.1	4.4	0.7	1.4	0.1	0.2	0.6	0.5	1.4	0.3	1.2	2.1	1.2
BMI	0.1	0.6	1.7	0.3	0.5	1.2	0.8	0.1	0.5	1.3	0.8	1.1	0.3	-0.5
Allergy or Eczema	0.1	0.3	1.3	-0.1	-0.5	-0.6	-0.2	0.1	-0.4	-0.3	-0.3	-0.7	-1.1	-0.5
Hair Pigment	0.1	2.4	7.9	-1.0	-0.7	-1.0	-1.9	-1.5	-1.3	-0.3	-1.0	-2.6	2.8	0.3
Ever used hormone-replacement therapy (HRT)	0.1	0.2	0.7	-0.4	0.4	0.3	-0.2	-0.4	-0.2	0.6	-0.6	0.8	-0.0	0.2
Trunk fat percentage	0.1	0.3	0.8	-0.5	0.3	0.3	-0.6	0.7	-0.3	-0.5	-0.1	0.1	0.7	-0.9
Trunk fat mass	0.1	0.6	3.7	-0.1	0.0	-0.4	-0.1	1.0	0.0	-0.9	0.4	-0.6	0.7	-1.9
Past tobacco smoking	0.1	0.3	0.9	-0.2	0.5	-0.8	-0.3	-0.2	-0.4	-0.3	-0.8	-0.3	-0.2	0.9
Alcohol usually taken with meals	0.1	0.2	1.0	0.1	0.1	-0.7	-0.0	-0.3	0.1	-0.8	-0.1	-1.0	0.2	-0.0
Neuroticism score	0.1	0.2	0.7	0.0	0.6	-0.0	-0.3	0.4	-0.4	0.5	-0.1	0.8	-0.5	0.4
Hip circumference	0.1	0.3	0.7	-0.8	-0.5	-0.1	-0.8	-0.2	-0.7	-0.6	-0.4	-0.1	-0.7	-0.8
Time employed in main current job	0.1	0.1	0.9	0.1	0.9	0.1	0.3	0.1	-0.3	-0.4	-0.0	0.2	0.2	0.0
Noisy workplace	0.1	0.1	0.5	0.2	-0.2	-0.4	0.3	0.3	0.7	-0.5	0.1	-0.1	-0.1	-0.6
Arm fat mass (right)	0.1	0.3	1.5	0.2	0.5	0.5	0.3	0.8	0.3	0.1	0.7	0.3	0.4	-1.2
Tense / ‘highly strung’	0.1	0.2	0.8	0.0	0.5	-0.6	-0.3	0.9	-0.5	-0.1	-0.0	0.2	-0.6	-0.3
Body fat percentage	0.1	0.4	0.9	-0.1	0.7	0.8	-0.1	1.0	0.1	0.2	0.4	0.5	0.8	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.5	-0.0	0.0	0.0	0.0	0.2	-0.2	0.6	-0.7	0.5	0.6	0.3
Qualifications: College or University degree	0.1	0.3	1.1	0.1	-0.1	-0.8	-0.1	0.9	-0.3	-0.6	-0.3	-0.5	0.2	-1.0
Smoking status: Previous	0.1	0.2	0.7	-0.0	-0.2	0.7	-0.1	-0.2	-0.2	0.3	0.4	0.3	0.8	-0.4
Arm fat percentage (left)	0.1	0.5	1.6	-0.1	0.9	1.1	-0.0	0.7	0.0	0.7	0.4	1.3	0.4	-0.2
Osteoporosis (self-reported)	0.1	0.1	0.3	0.3	-0.3	0.1	0.1	-0.0	0.5	0.4	0.1	0.5	0.4	0.2
Arm fat mass (left)	0.1	0.3	2.1	-0.0	0.3	-0.0	0.0	0.6	0.0	-0.2	0.5	0.1	0.2	-1.4
Irritability	0.1	0.2	0.8	0.2	0.1	-0.6	-0.0	0.1	0.1	-0.4	-0.5	0.4	0.2	-0.9
Tanning	0.0	0.2	0.8	-0.2	-0.2	0.9	0.3	-0.1	-0.2	0.4	0.2	0.7	-0.3	-0.3

Hub : Genes

WDR35

Models

Trait associations