Hub : Genes

WDR67

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.2070 0.0350 3.8e-15 0.136 0.152 0.171 0.18 0.175 3.2e-16 4.5e-18 2.6e-20 2.1e-21 9.3e-21
2 TCGA Kidney Renal Clear Cell Carcinoma 0.0361 0.0208 8.6e-03 0.006 0.011 0.014 NA 0.017 6.2e-02 2.0e-02 9.6e-03 NA 4.8e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 1.9 3.0 3.1 -1.7 1.8
Bipolar Disorder or Schizophrenia 0.6 1.6 3.1 -0.1 1.8
Depressed Affect (Nagel 2018) 1.6 3.4 5.2 -1.3 2.3
Depression (Nagel 2018) 2.6 3.9 5.5 -1.5 2.3
Intelligence (Savage-Jansen 2018) 1.1 3.5 6.2 0.9 -2.5
Neuroticism (Nagel 2018) 1.8 4.2 4.3 -2.1 2.0
Schizophrenia (2018) 0.6 1.2 1.7 1.3 0.8
Schizophrenia vs Biploar Disorder 1.6 2.2 3.1 1.8 -1.1
Worry (Nagel 2018) 1.9 4.0 4.4 -2.1 1.9
Alzheimer’s Disease (in mother) 4.6 5.3 8.6 -1.4 2.9
Alzheimer’s Disease (in father) 2.9 3.1 4.5 -1.3 2.1
Alzheimer’s Disease (including proxy) 5.6 8.1 11.8 -2.1 3.4
Crohns Disease (2017) 0.4 0.9 0.9 1.0 -0.9
Irritable Bowel Disease (IBD) 0.4 0.9 1.7 0.3 -1.3
Ulcerative Colitis (UC) 0.7 1.3 2.4 -0.5 -1.6
Major Depression (MDD) 0.5 0.6 0.6 -0.8 0.7
Reaction Time 0.0 0.0 0.1 -0.2 -0.0
Verbal and Numeric Reasoning (VNR) 0.0 0.1 0.1 -0.3 -0.3
Breast Cancer 0.6 1.5 2.7 0.6 1.7
Ovarian Cancer 0.4 0.5 1.0 -0.3 1.0
Prostate Cancer 0.9 1.3 2.6 1.6 0.1
Age at First Birth 0.5 0.7 0.9 0.7 -1.0
Bipolar Disorder (2011) 2.5 2.5 2.7 -1.6 1.5
Body Mass Index (BMI) (2010) 2.0 2.7 2.8 1.7 -1.6
Coronary Artery Disease (CAD) 0.3 0.4 0.7 0.0 0.8
Crohns Disease (2012) 0.1 0.2 0.3 -0.6 -0.2
Mean Putamen Volume 0.2 0.3 0.4 0.4 0.6
Fasting Glucose 0.7 0.9 1.5 -1.2 -0.5
HbA1C 1.2 1.3 2.0 0.8 -1.4
HDL Cholesterol 0.6 1.1 1.2 -1.0 1.1
LDL Cholesterol 0.5 0.8 1.2 1.1 0.6
Lupus 0.1 0.1 0.2 -0.2 -0.4
Neuroticism (2016) 0.0 0.0 0.0 -0.0 0.2
Primary Biliary Cirrhosis 0.3 0.4 0.6 -0.3 0.8
Rheumatoid Arthritis 0.3 0.4 0.8 0.9 0.1
Schizophrenia (2014) 0.4 0.9 0.9 0.9 0.9
Triglycerides 0.1 0.1 0.3 0.5 -0.2
Type 2 Diabetes (T2D) (2012) 0.6 0.7 1.4 -1.2 0.3
Ulcerative Colitis 0.3 0.4 0.7 -0.4 -0.8
Blood Eosinophil Count 0.3 2.0 3.3 0.8 -1.8
Blood Platelet Count 0.3 4.0 6.8 -2.6 1.1
Blood Red Count 0.1 1.2 1.9 -1.4 0.6
Blood White Count 0.0 0.0 0.0 0.2 -0.0
Heel T-Score 0.5 3.9 7.8 -2.8 0.2
BMI 4.3 25.0 28.2 5.3 -4.7
Height 0.5 8.9 14.3 1.9 -3.8
Waist Hip Ratio (WHR) 0.0 0.0 0.1 0.1 0.2
Systolic Blood Pressure 0.6 2.9 3.8 -1.5 1.9
Smoking Status 0.5 1.2 1.6 -0.9 1.3
Allergy or Eczema 0.1 0.2 0.5 0.1 -0.7
Cardiovascular Disease 0.2 0.7 1.2 -0.4 1.1
Hypothyroidism (self reported) 0.2 0.4 0.6 0.8 0.4
Respiratory disease 0.0 0.0 0.0 0.1 -0.1
Type 2 Diabetes (T2D) (2018) 0.0 0.0 0.0 -0.2 0.0
Lung FEV1/FVC ratio 0.0 0.2 0.3 0.6 -0.2
Lung FVC 0.7 3.8 6.6 -2.6 1.0
Neuroticism 0.7 1.8 2.6 -1.0 1.6
Chronotype (morning person) 0.4 0.9 1.7 -0.3 -1.3
Hair Pigment 0.0 0.1 0.1 -0.4 0.3
Tanning 0.0 0.0 0.1 0.0 -0.3
Hand grip strength (left) 0.8 2.2 2.6 -1.3 1.6
Number of treatments/medications taken 0.3 0.5 1.0 -0.3 1.0
Average weekly spirits intake 0.4 0.5 0.9 -0.2 0.9
Sensitivity / hurt feelings 0.1 0.2 0.3 -0.1 0.6
Frequency of depressed mood in last 2 weeks 2.0 2.8 4.7 -0.9 2.2
Hearing difficulty/problems: Yes 0.3 0.4 0.6 0.5 0.8
Relative age of first facial hair 0.4 0.9 1.2 1.1 -0.8
Other serious medical condition/disability diagnosed by doctor 0.7 1.0 1.4 0.7 -1.2
Ever used hormone-replacement therapy (HRT) 2.8 3.5 7.0 0.0 2.6
Ever had hysterectomy (womb removed) 0.2 0.2 0.3 0.5 0.5
Systolic blood pressure, automated reading 0.2 0.7 1.0 1.0 -0.6
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 0.4 0.2 -0.6
Angina 0.1 0.1 0.2 0.5 0.2
Medication for hormone replacement therapy 1.2 1.4 2.5 0.5 1.6
Vitamin and mineral supplements 3.7 5.1 8.3 1.4 -2.9
Supplements: Zinc 0.1 0.1 0.1 0.4 -0.3
Medication: Co-codamol 0.2 0.2 0.4 0.6 -0.2
Medication: Metformin 0.2 0.3 0.5 -0.2 -0.7
Diabetes (father) 0.2 0.3 0.4 -0.3 -0.6
Diabetes (mother) 1.3 1.7 3.0 0.6 -1.7
Severe depression (siblings) 2.4 2.7 5.2 0.5 2.3
Pack years adult smoking proportion 0.6 1.0 1.2 1.1 0.8
Impedance of leg (right) 3.4 16.4 18.8 -4.3 3.8
Leg fat-free mass (left) 4.2 22.1 23.8 4.9 -4.5
Trunk fat percentage 2.5 10.0 13.2 2.6 -3.6
Hand grip strength (right) 0.5 1.2 1.3 -1.1 1.1
Townsend deprivation index at recruitment 0.7 1.0 2.0 0.4 1.4
Current tobacco smoking 0.7 1.1 1.5 1.2 0.9
Average weekly fortified wine intake 0.0 0.0 0.1 -0.2 -0.2
Maternal smoking around birth 0.2 0.4 0.4 0.5 -0.7
Fed-up feelings 1.1 2.0 3.7 -0.6 1.9
Frequency of unenthusiasm / disinterest in last 2 weeks 1.5 2.0 3.3 -0.8 1.8
Relative age voice broke 0.1 0.1 0.1 -0.4 -0.2
Taking other prescription medications 0.4 0.6 0.8 -0.9 0.7
Age when periods started (menarche) 0.1 0.2 0.3 0.2 -0.5
Bilateral oophorectomy (both ovaries removed) 0.2 0.2 0.3 -0.6 0.3
Heel bone mineral density (BMD) T-score, automated (left) 0.6 1.3 2.5 -0.4 -1.6
Tinnitus: Yes, but not now, but have in the past 0.6 0.6 0.8 -0.9 0.7
Qualifications: CSEs or equivalent 0.1 0.1 0.1 -0.1 -0.4
Serious illness, injury or assault to yourself 0.7 0.8 1.5 -1.2 0.3
High blood pressure 0.2 0.5 0.7 0.8 -0.5
Hayfever, allergic rhinitis or eczema 0.1 0.3 0.5 0.4 -0.7
Multivitamins +/- minerals 2.4 3.1 4.6 -1.3 2.1
Stomach or abdominal pain in last month 0.3 0.3 0.6 -0.0 0.8
Supplements: Glucosamine 0.3 0.3 0.6 -0.3 0.7
Diverticular disease/diverticulitis (self-reported) 0.7 0.9 0.9 -0.9 -0.9
Medication: Atenolol 0.1 0.1 0.1 0.3 -0.3
Medication: Levothyroxine sodium 0.3 0.5 0.9 -0.3 1.0
Sitting height 0.7 5.1 6.4 1.9 -2.5
Chronic bronchitis/emphysema (father) 0.7 0.8 1.3 0.6 -1.1
High blood pressure (mother) 0.4 0.5 1.1 0.0 1.0
Body mass index (BMI) 3.8 16.2 16.6 4.1 -4.0
Impedance of leg (left) 3.2 15.4 19.7 -4.4 3.3
Leg predicted mass (left) 4.2 22.4 24.4 4.9 -4.5
Trunk fat mass 3.6 15.5 18.5 3.5 -4.3
Waist circumference 4.4 16.2 16.6 4.1 -4.0
Number of incorrect matches in round 1.3 2.2 4.3 0.3 2.1
Past tobacco smoking 0.8 1.4 2.3 0.7 1.5
Alcohol usually taken with meals 0.7 1.2 2.3 -1.5 -0.2
Nervous feelings 0.5 0.9 1.3 -1.2 0.7
Frequency of tenseness / restlessness in last 2 weeks 1.7 2.6 4.5 -0.8 2.1
Hearing difficulty/problems with background noise 0.2 0.4 0.6 0.8 0.3
Hair/balding pattern: Pattern 2 0.4 0.6 0.8 0.6 -0.9
Had menopause 1.0 1.3 2.4 1.6 -0.4
Had other major operations 0.4 0.5 0.8 -0.9 0.5
Forced vital capacity (FVC) 0.5 1.8 3.6 -1.9 -0.0
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.2 1.5 -0.9 -1.2
Ever unenthusiastic/disinterested for a whole week 0.8 1.0 2.0 -1.4 0.3
Qualifications: None of the above 1.3 2.8 4.9 2.2 -0.8
Financial difficulties in last 2 years 0.1 0.1 0.3 -0.5 -0.0
Mouth/teeth dental problems 0.0 0.0 0.1 0.0 0.2
Heart attack 0.0 0.0 0.0 -0.2 0.0
Allergy 0.3 0.7 0.8 -0.8 0.9
Pain all over the body in last month 2.5 2.7 5.0 -0.6 2.2
Diabetes (self-reported) 0.2 0.3 0.6 -0.8 0.2
Hayfever/allergic rhinitis (self-reported) 1.9 2.5 4.6 0.6 -2.2
Medication: Ramipril 0.1 0.1 0.3 0.0 -0.5
Medication: Simvastatin 0.7 1.0 1.3 0.9 -1.1
Fluid intelligence score 0.0 0.0 0.1 -0.0 -0.3
Illnesses of siblings 0.1 0.1 0.2 -0.4 0.1
Neuroticism score 0.9 1.9 2.5 -1.1 1.6
Weight 4.2 20.7 21.6 4.5 -4.7
Impedance of arm (right) 1.0 4.6 4.7 -2.2 2.1
Arm fat percentage (right) 2.7 10.5 10.9 3.2 -3.3
Trunk fat-free mass 2.5 14.3 15.8 4.0 -3.6
Hip circumference 4.8 20.6 21.8 4.4 -4.7
Time employed in main current job 4.8 5.5 6.2 2.5 -2.2
Alcohol intake versus 10 years previously 0.4 0.6 0.8 0.9 -0.6
Father’s age at death 0.5 0.7 1.1 -0.5 1.0
Worrier / anxious feelings 2.0 3.8 4.9 -2.2 1.6
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.8 1.6 -0.1 1.3
Falls in the last year 1.1 1.5 1.7 1.3 -1.2
Hair/balding pattern: Pattern 3 0.2 0.4 0.6 0.4 0.7
Number of live births 0.2 0.3 0.4 0.6 0.4
Forced expiratory volume in 1-second (FEV1) 0.3 1.1 2.0 -1.4 -0.5
Pulse rate 1.1 1.9 2.6 1.6 -1.1
Happiness 2.4 3.0 5.3 -0.8 2.3
Noisy workplace 0.2 0.2 0.4 0.6 0.2
Qualifications: A levels/AS levels or equivalent 1.5 3.3 5.0 -1.3 2.2
Serious illness, injury or assault of a close relative in last 2 years 3.4 3.9 4.9 -2.2 1.7
Mouth/teeth dental problems: Dentures 0.1 0.2 0.4 -0.7 -0.0
Asthma 0.1 0.2 0.2 0.4 0.3
Medication: Ibuprofen (e.g. Nurofen) 0.2 0.2 0.4 0.0 0.6
Medication: Cholesterol lowering 0.2 0.3 0.6 -0.8 0.1
Depression (self-reported) 1.1 1.4 2.6 -0.4 1.6
Medication: Lansoprazole 1.7 1.9 2.3 1.3 -1.5
Prospective memory result 1.8 2.2 3.9 -0.7 2.0
Lung cancer (father) 0.0 0.1 0.1 0.3 -0.1
Illnesses of mother 0.2 0.2 0.4 -0.0 -0.6
Forced expiratory volume in 1-second (FEV1), Best measure 0.6 1.8 3.3 -1.8 -0.5
Pulse wave Arterial Stiffness index 0.3 0.4 0.4 0.7 -0.5
Impedance of arm (left) 0.7 3.3 4.3 -2.1 1.5
Arm fat mass (right) 3.9 16.1 17.2 3.9 -4.1
Trunk predicted mass 2.6 14.6 15.7 4.0 -3.7
Standing height 0.3 2.6 3.6 1.3 -1.9
Length of working week for main job 4.3 4.7 5.2 2.1 -2.3
Exposure to tobacco smoke at home 2.9 3.2 5.7 2.4 -0.8
Breastfed as a baby 0.9 1.1 1.6 -1.3 0.8
Tense / ‘highly strung’ 0.7 1.1 1.7 -0.7 1.3
Seen doctor (GP) for nerves, anxiety, tension or depression 4.4 6.7 8.5 -2.2 2.9
Hair/balding pattern: Pattern 4 2.4 5.8 7.2 2.1 -2.7
Birth weight of first child 1.3 2.3 2.6 -1.4 -1.6
Peak expiratory flow (PEF) 0.0 0.1 0.2 0.4 0.0
Pulse wave reflection index 0.6 0.7 1.1 -0.6 1.0
Ever highly irritable/argumentative for 2 days 0.1 0.1 0.1 0.3 0.3
Loud music exposure frequency 0.4 0.4 0.8 0.2 0.9
Qualifications: O levels/GCSEs or equivalent 1.7 2.7 5.0 -0.6 2.2
Mouth/teeth dental problems: Bleeding gums 0.1 0.1 0.2 -0.5 -0.1
Blood clot in the leg (DVT) 0.1 0.1 0.2 0.2 -0.5
Medication: Paracetamol 0.4 0.7 1.0 1.0 0.6
Headache pain in last month 0.7 1.2 2.0 1.4 -0.7
Medication for cholesterol, blood pressure or diabetes 0.0 0.1 0.1 0.3 0.2
Glaucoma (self-reported) 0.1 0.1 0.1 -0.4 0.1
Gout (self-reported) 1.7 2.3 3.0 1.3 -1.7
Hypothyroidism/myxoedema (self-reported) 0.0 0.1 0.2 -0.0 0.4
Medication: Amlodipine 2.4 3.4 5.0 2.2 -1.3
Medication: Ventolin 100micrograms inhaler 0.1 0.1 0.2 0.1 0.5
Birth weight 0.1 0.2 0.4 -0.1 0.6
Chronic bronchitis/emphysema (mother) 0.9 1.0 1.8 1.3 -0.4
High blood pressure (siblings) 0.8 1.1 1.8 -0.7 1.3
Forced vital capacity (FVC), Best measure 0.5 2.0 3.9 -2.0 -0.3
Body fat percentage 2.4 9.3 11.5 2.7 -3.4
Leg fat percentage (right) 1.5 5.3 6.5 2.0 -2.5
Arm fat-free mass (right) 2.8 14.1 14.6 3.7 -3.8
Exposure to tobacco smoke outside home 3.6 4.9 7.5 2.7 -1.5
Comparative body size at age 10 0.1 0.2 0.3 0.6 -0.0
Number of full brothers 1.1 1.4 2.1 1.4 -0.9
Worry too long after embarrassment 0.1 0.1 0.2 -0.2 -0.5
Seen a psychiatrist for nerves, anxiety, tension or depression 1.6 2.1 2.7 -1.2 1.7
Wheeze or whistling in the chest in last year 0.1 0.1 0.3 0.1 0.5
Number of children fathered 1.2 1.3 2.1 -1.5 0.8
Reason for reducing amount of alcohol drunk: Health precaution 2.7 3.1 3.1 1.8 -1.8
Age at first live birth 0.3 0.4 0.8 -0.9 -0.3
Pulse wave peak to peak time 0.3 0.4 0.5 -0.7 0.5
Health satisfaction 0.2 0.2 0.5 0.7 -0.1
Shortness of breath walking on level ground 0.1 0.1 0.1 0.4 -0.4
Qualifications: College or University degree 0.1 0.2 0.5 -0.7 -0.2
Eye problems/disorders: None of the above 1.2 1.4 1.6 1.3 -1.1
Mouth/teeth dental problems: Loose teeth 0.3 0.4 0.7 0.9 0.3
Emphysema/chronic bronchitis 0.4 0.4 0.7 -0.8 0.4
Medication for pain relief, constipation, heartburn 0.2 0.4 0.8 -0.2 -0.9
Neck or shoulder pain in last month 0.5 0.7 1.3 1.2 -0.3
Medication: Blood pressure 0.1 0.1 0.2 -0.0 -0.5
Angina (self-reported) 0.2 0.3 0.6 0.8 0.2
Migraine (self-reported) 0.3 0.4 0.4 0.6 -0.6
Medication: Ibuprofen 0.4 0.5 0.8 0.4 0.9
Medication: Allopurinol 0.1 0.2 0.3 0.5 0.3
Medication: Omeprazole 0.3 0.4 0.4 -0.6 0.6
Medication: Seretide 50 evohaler 0.3 0.3 0.4 0.6 -0.5
Mean time to correctly identify matches 0.1 0.2 0.4 -0.6 0.2
Heart disease (mother) 0.0 0.0 0.0 -0.1 0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.1 0.1 0.2 -0.2 0.5
Whole body fat mass 3.7 15.6 17.8 3.7 -4.2
Leg fat mass (right) 2.9 11.2 12.4 3.2 -3.5
Arm predicted mass (right) 2.8 14.4 15.3 3.7 -3.9
Pulse rate, automated reading 0.7 2.1 4.3 0.1 -2.1
Alcohol intake frequency. 0.3 0.6 0.6 0.8 0.8
Comparative height size at age 10 0.6 3.5 5.3 1.3 -2.3
Number of full sisters 0.9 1.1 1.7 1.3 -0.6
Suffer from ‘nerves’ 0.7 1.2 2.3 -0.3 1.5
Overall health rating 0.0 0.1 0.1 0.2 -0.3
Chest pain or discomfort 0.1 0.1 0.2 0.4 0.2
Had major operations 1.2 1.4 2.6 -1.6 0.5
Age at last live birth 0.3 0.4 0.9 -0.0 -0.9
Family relationship satisfaction 0.9 1.1 1.8 -0.6 1.3
Leg pain on walking 2.2 2.7 4.5 2.1 -0.9
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.6 0.7 -0.7 0.8
Commuting to job workplace: Car/motor vehicle 0.4 0.4 0.6 0.8 -0.5
Illness, injury, bereavement, stress in last 2 years 1.3 1.6 2.6 1.6 -0.8
Medication: Aspirin 0.2 0.2 0.4 -0.6 -0.1
Supplements: Vitamin C 2.0 2.4 4.3 -0.6 2.1
Knee pain experienced in last month 1.1 1.8 2.5 1.0 -1.6
Hypertension (Self-reported) 0.2 0.5 0.8 0.9 -0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.1 0.2 0.4 -0.2
Illnesses of father: Heart disease 0.1 0.1 0.2 -0.2 -0.4
Illnesses of siblings: Diabetes 2.3 2.8 5.5 0.4 -2.4
Smoking status: Previous 1.4 2.0 2.7 -1.2 -1.6
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.6 1.0 -1.0 0.4
Whole body fat-free mass 3.5 19.8 21.2 4.6 -4.3
Leg fat-free mass (right) 4.5 24.1 24.5 4.9 -4.9
Arm fat percentage (left) 3.0 11.9 13.1 3.3 -3.6
Average weekly red wine intake 0.8 1.2 2.4 0.1 -1.6
Handedness (chirality/laterality): Left-handed 1.1 1.3 2.2 0.6 1.5
Mood swings 0.6 1.0 2.0 0.3 1.4
Loneliness, isolation 0.3 0.5 0.7 -0.4 0.9
Long-standing illness, disability or infirmity 0.8 1.1 1.3 1.0 -1.1
Ever had bowel cancer screening 0.5 0.5 1.0 0.1 -1.0
Diabetes diagnosed by doctor 0.0 0.0 0.1 -0.2 -0.2
Ever had stillbirth, spontaneous miscarriage or termination 1.3 1.4 2.2 -1.5 0.8
Friendships satisfaction 0.9 1.1 2.1 0.2 1.5
Qualifications: nursing, teaching 0.6 0.9 1.0 1.0 -1.0
Commuting to job workplace: Walk 0.2 0.2 0.3 -0.4 0.5
Eye problems/disorders: Cataract 3.5 4.1 5.5 -1.7 2.3
Mouth/teeth dental problems: Mouth ulcers 0.1 0.2 0.3 0.5 -0.2
Medication for cholesterol 0.7 1.0 2.0 -0.3 -1.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 3.1 3.6 6.6 0.9 2.6
Back pain experienced in last month 0.6 0.9 1.3 -0.7 1.1
Mineral and other dietary supplements 0.4 0.5 0.9 0.3 -1.0
Breast cancer (self-reported) 1.3 1.5 1.7 -1.2 1.3
Asthma (self-reported) 0.1 0.2 0.2 0.5 0.4
Osteoporosis (self-reported) 3.5 4.4 5.4 -2.3 1.9
Osteoarthritis (self-reported) 3.2 4.1 5.9 2.4 -1.5
Medication: Aspirin 0.0 0.0 0.1 -0.3 0.0
Medication: Gliclazide 0.0 0.0 0.1 0.3 0.2
Illnesses of father: None of the above (group 1) 0.0 0.0 0.0 -0.0 -0.2
Smoking status: Current 0.8 1.2 1.4 1.0 1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.1 0.2 -0.3 -0.4
Whole body water mass 3.6 20.7 21.9 4.7 -4.4
Leg predicted mass (right) 4.6 24.5 24.9 5.0 -4.9
Arm fat mass (left) 4.4 18.1 19.7 4.1 -4.4
Number of self-reported non-cancer illnesses 0.4 0.6 1.2 0.2 -1.1
Average weekly champagne plus white wine intake 0.8 1.1 1.4 -1.2 0.9
Miserableness 0.6 1.0 1.4 -0.8 1.2
Guilty feelings 2.0 3.1 5.3 -1.0 2.3
Wears glasses or contact lenses 0.9 1.0 1.0 -1.0 1.0
Ever taken oral contraceptive pill 1.2 1.4 2.2 -1.5 0.7
Hearing aid user 0.8 0.9 1.1 0.8 -1.0
Mother’s age at death 1.1 1.4 2.5 0.5 -1.6
Financial situation satisfaction 0.3 0.3 0.6 0.3 0.8
Tinnitus: Yes, now most or all of the time 0.2 0.2 0.3 0.5 0.3
Commuting to job workplace: Public transport 0.0 0.0 0.0 0.2 0.2
Eye problems/disorders: Glaucoma 0.1 0.1 0.2 -0.2 0.5
Medication: Blood pressure 0.2 0.4 0.5 0.5 0.7
Pain type(s) experienced in last month: Hip pain 1.3 1.6 3.0 1.7 -0.5
Supplements: Fish oil (including cod liver oil) 0.5 0.7 0.8 -0.8 0.9
High cholesterol (Self-reported) 0.1 0.1 0.2 -0.2 0.4
Medication: Bendroflumethiazide 0.1 0.1 0.2 -0.2 0.5
Medication: Paracetamol 0.3 0.4 0.9 0.1 0.9
Medication: Lisinopril 0.2 0.2 0.3 0.4 -0.5
Medication: Atorvastatin 1.8 2.2 2.2 -1.5 1.5
Illnesses of father: High blood pressure 0.3 0.3 0.5 -0.4 0.7
Alcohol drinker status: Never 1.5 1.8 2.9 -0.8 1.7
Ever smoked 0.6 1.1 1.1 -1.1 -1.1
Basal metabolic rate 3.8 21.2 22.1 4.7 -4.5
Leg fat percentage (left) 2.0 7.2 9.4 2.2 -3.1
Arm fat-free mass (left) 2.8 14.3 14.9 3.7 -3.9
Number of operations (self-reported) 1.3 1.9 3.1 -1.7 0.8
Average weekly beer plus cider intake 0.7 0.9 1.8 -0.4 1.3
Irritability 0.3 0.5 0.9 -0.9 0.3
Risk taking 0.7 1.0 1.9 -0.4 1.4
Ever had prostate specific antigen (PSA) test 1.2 1.4 2.8 -1.7 0.3
Fractured/broken bones in last 5 years 0.4 0.5 0.9 0.9 0.3
Age started oral contraceptive pill 0.0 0.0 0.0 -0.2 0.1
Diastolic blood pressure, automated reading 1.6 5.0 5.3 2.3 -2.2
Ever depressed for a whole week 0.6 0.8 1.0 -1.0 0.8
Unable to work because of sickness or disability 0.6 0.8 0.9 0.8 1.0
Commuting to job workplace: Cycle 1.4 1.7 1.8 -1.4 1.2
Myopia 0.3 0.4 0.8 -0.3 0.9
Vascular/heart problems diagnosed by doctor 0.2 0.4 0.8 -0.9 0.3
Cholesterol lowering medication 0.0 0.0 0.0 -0.1 0.1
Medication: Omeprazole (e.g. Zanprol) 0.4 0.5 0.6 -0.7 0.8
Pain experienced in last month 0.7 1.2 2.4 -1.6 0.1
Supplements: Calcium 0.9 1.0 1.8 -0.5 1.3
Basal cell carcinoma (self-reported) 0.2 0.2 0.5 0.7 0.0
Heart attack/myocardial infarction (self-reported) 0.1 0.1 0.2 -0.4 -0.1
Deep venous thrombosis (DVT) (self-reported) 0.1 0.1 0.2 0.3 -0.4
Heart disease (siblings) 0.2 0.2 0.5 0.7 -0.1
Alcohol drinker status: Previous 0.0 0.0 0.0 -0.1 -0.1
Pack years of smoking 1.0 1.4 2.7 1.6 0.4
Impedance of whole body 2.2 11.0 13.9 -3.7 2.8
Leg fat mass (left) 3.0 11.7 13.5 3.1 -3.7
Arm predicted mass (left) 3.0 15.2 16.6 3.7 -4.1