Hub : Genes

WDR76

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.050 0.023 7.1e-07 0.037 0.051 0.049 NA 0.053 2.3e-05 7.4e-07 1.2e-06 NA 4.9e-07
2 TCGA Uterine Corpus Endometrial Carcinoma 0.131 0.085 1.7e-03 0.097 0.117 0.089 NA 0.107 1.2e-03 3.9e-04 1.8e-03 NA 6.5e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.8 1.3 1.5 -1.1 1.2
Bipolar Disorder or Schizophrenia 5.1 12.4 13.2 -3.4 3.6
Depressed Affect (Nagel 2018) 0.4 0.9 1.1 -0.8 1.0
Depression (Nagel 2018) 2.3 3.4 3.6 -1.9 1.8
Intelligence (Savage-Jansen 2018) 4.7 14.3 15.1 3.9 -3.7
Neuroticism (Nagel 2018) 0.0 0.0 0.1 0.3 -0.1
Schizophrenia (2018) 6.2 12.9 13.6 -3.5 3.7
Schizophrenia vs Biploar Disorder 0.0 0.0 0.0 0.1 -0.0
Worry (Nagel 2018) 0.3 0.7 1.0 1.0 -0.6
Alzheimer’s Disease (in mother) 2.3 2.6 2.8 -1.7 1.6
Alzheimer’s Disease (in father) 0.1 0.1 0.1 0.3 -0.3
Alzheimer’s Disease (including proxy) 1.9 2.7 2.8 -1.6 1.7
Crohns Disease (2017) 0.9 2.0 2.2 1.3 -1.5
Irritable Bowel Disease (IBD) 0.2 0.5 0.6 0.8 -0.7
Ulcerative Colitis (UC) 0.1 0.1 0.2 -0.3 0.4
Major Depression (MDD) 7.0 8.4 8.9 -2.8 3.0
Reaction Time 1.8 3.5 3.6 1.8 -1.9
Verbal and Numeric Reasoning (VNR) 2.8 6.7 7.6 2.8 -2.4
Breast Cancer 4.2 10.1 11.3 3.0 -3.4
Ovarian Cancer 7.1 9.4 9.5 3.1 -3.1
Prostate Cancer 1.3 1.8 2.3 -1.2 1.5
Age at First Birth 11.1 16.1 17.7 3.8 -4.2
Bipolar Disorder (2011) 1.7 1.6 1.9 -1.2 1.4
Body Mass Index (BMI) (2010) 10.0 13.6 14.5 -3.8 3.6
Coronary Artery Disease (CAD) 0.7 0.9 1.0 1.0 -0.9
Crohns Disease (2012) 3.9 6.3 6.9 2.4 -2.6
Mean Putamen Volume 1.1 1.2 1.5 1.2 -1.0
Fasting Glucose 0.2 0.3 0.4 -0.6 0.4
HbA1C 2.1 2.4 2.7 -1.6 1.4
HDL Cholesterol 2.4 4.1 4.2 -2.0 2.0
LDL Cholesterol 0.5 0.7 0.8 -0.8 0.9
Lupus 6.6 10.0 10.4 3.1 -3.2
Neuroticism (2016) 0.4 0.5 0.6 0.8 -0.7
Primary Biliary Cirrhosis 0.4 0.5 0.8 -0.9 0.6
Rheumatoid Arthritis 0.1 0.2 0.2 -0.3 0.5
Schizophrenia (2014) 6.6 14.6 16.2 -3.6 4.0
Triglycerides 10.1 16.6 17.4 4.2 -4.0
Type 2 Diabetes (T2D) (2012) 0.0 0.0 0.1 0.2 -0.3
Ulcerative Colitis 0.1 0.1 0.1 -0.3 0.3
Blood Eosinophil Count 0.1 0.6 1.1 0.2 -1.1
Blood Platelet Count 7.7 88.9 96.4 9.8 -9.0
Blood Red Count 3.6 34.7 35.2 -5.9 5.8
Blood White Count 0.3 1.9 2.3 1.5 -1.2
Heel T-Score 0.9 6.8 6.9 2.6 -2.6
BMI 3.6 20.6 20.9 -4.6 4.5
Height 0.0 0.2 0.3 -0.5 0.2
Waist Hip Ratio (WHR) 0.0 0.0 0.0 0.1 0.2
Systolic Blood Pressure 1.7 8.6 8.8 3.0 -2.9
Smoking Status 0.1 0.2 0.3 -0.3 0.6
Allergy or Eczema 1.1 2.8 2.9 -1.7 1.7
Cardiovascular Disease 1.1 3.5 3.5 1.9 -1.9
Hypothyroidism (self reported) 0.0 0.1 0.1 -0.2 0.3
Respiratory disease 0.1 0.2 0.3 -0.4 0.5
Type 2 Diabetes (T2D) (2018) 1.8 3.4 3.6 -1.9 1.8
Lung FEV1/FVC ratio 0.0 0.1 0.2 0.5 -0.1
Lung FVC 1.0 4.9 5.7 2.0 -2.4
Neuroticism 0.0 0.0 0.0 0.1 0.1
Chronotype (morning person) 2.3 5.4 6.2 2.5 -2.1
Hair Pigment 0.1 2.0 2.8 -1.1 1.7
Tanning 0.0 0.1 0.2 -0.4 0.2
Hand grip strength (left) 0.6 1.5 1.6 -1.2 1.3
Number of treatments/medications taken 0.6 1.2 1.4 1.0 -1.2
Average weekly spirits intake 0.0 0.0 0.1 0.0 -0.3
Sensitivity / hurt feelings 0.4 0.7 0.7 -0.8 0.8
Frequency of depressed mood in last 2 weeks 3.4 4.8 5.2 -2.3 2.1
Hearing difficulty/problems: Yes 1.4 2.2 2.5 -1.4 1.6
Relative age of first facial hair 0.6 1.3 1.4 1.2 -1.1
Other serious medical condition/disability diagnosed by doctor 0.0 0.0 0.0 -0.2 0.1
Ever used hormone-replacement therapy (HRT) 0.2 0.2 0.2 -0.4 0.5
Ever had hysterectomy (womb removed) 1.4 1.6 1.7 -1.2 1.3
Systolic blood pressure, automated reading 0.8 2.4 2.7 1.6 -1.4
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 0.3 -0.4 0.5
Angina 1.1 1.4 1.5 1.2 -1.2
Medication for hormone replacement therapy 0.0 0.1 0.1 -0.0 0.3
Vitamin and mineral supplements 6.1 8.3 8.7 -2.8 2.9
Supplements: Zinc 6.7 7.3 7.7 2.6 -2.8
Medication: Co-codamol 2.1 2.4 2.5 -1.6 1.5
Medication: Metformin 1.1 1.6 1.9 -1.4 1.1
Diabetes (father) 7.5 9.2 9.3 -3.0 3.0
Diabetes (mother) 0.3 0.3 0.3 -0.6 0.6
Severe depression (siblings) 1.0 1.2 1.5 -0.9 1.2
Pack years adult smoking proportion 1.0 1.5 1.9 -1.1 1.4
Impedance of leg (right) 3.9 18.7 20.2 4.5 -4.2
Leg fat-free mass (left) 3.1 16.2 17.1 -4.1 3.9
Trunk fat percentage 1.7 6.7 6.7 -2.6 2.6
Hand grip strength (right) 0.2 0.4 0.5 -0.7 0.6
Townsend deprivation index at recruitment 3.5 5.0 5.2 -2.3 2.2
Current tobacco smoking 0.7 1.2 1.5 -0.9 1.2
Average weekly fortified wine intake 2.7 3.2 3.8 1.9 -1.6
Maternal smoking around birth 2.0 2.9 3.4 -1.5 1.9
Fed-up feelings 0.3 0.6 0.8 -0.6 0.9
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.1 1.3 -1.1 0.9
Relative age voice broke 0.4 0.5 0.6 0.7 -0.8
Taking other prescription medications 0.3 0.5 0.7 0.5 -0.9
Age when periods started (menarche) 2.5 6.0 6.1 2.5 -2.4
Bilateral oophorectomy (both ovaries removed) 0.0 0.0 0.0 -0.1 0.2
Heel bone mineral density (BMD) T-score, automated (left) 0.7 1.7 2.0 1.4 -1.2
Tinnitus: Yes, but not now, but have in the past 0.6 0.6 0.6 -0.8 0.8
Qualifications: CSEs or equivalent 0.0 0.0 0.1 -0.3 0.1
Serious illness, injury or assault to yourself 3.0 3.6 3.8 -1.8 1.9
High blood pressure 2.4 6.7 7.0 2.6 -2.5
Hayfever, allergic rhinitis or eczema 1.9 4.1 4.4 -1.9 2.1
Multivitamins +/- minerals 3.7 4.7 5.3 2.0 -2.3
Stomach or abdominal pain in last month 1.1 1.4 1.4 -1.2 1.2
Supplements: Glucosamine 0.5 0.7 0.8 0.7 -0.9
Diverticular disease/diverticulitis (self-reported) 3.4 4.0 4.4 -1.9 2.1
Medication: Atenolol 1.0 1.3 1.4 1.1 -1.2
Medication: Levothyroxine sodium 0.4 0.7 0.7 0.8 -0.8
Sitting height 0.5 3.2 3.8 -1.9 1.6
Chronic bronchitis/emphysema (father) 2.3 2.7 2.8 -1.6 1.7
High blood pressure (mother) 0.0 0.1 0.1 -0.2 0.3
Body mass index (BMI) 4.1 17.5 17.8 -4.2 4.1
Impedance of leg (left) 3.7 18.2 19.5 4.4 -4.1
Leg predicted mass (left) 3.1 16.5 17.3 -4.2 4.0
Trunk fat mass 2.6 11.1 11.2 -3.4 3.3
Waist circumference 4.1 14.9 15.2 -3.9 3.8
Number of incorrect matches in round 2.7 4.5 5.0 -2.2 2.0
Past tobacco smoking 0.0 0.0 0.1 0.1 -0.3
Alcohol usually taken with meals 0.2 0.4 0.4 -0.6 0.6
Nervous feelings 0.3 0.5 0.6 0.7 -0.7
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.5 0.8 -0.9 0.5
Hearing difficulty/problems with background noise 1.3 2.0 2.2 -1.3 1.5
Hair/balding pattern: Pattern 2 0.1 0.1 0.1 0.4 -0.1
Had menopause 1.2 1.4 1.7 -1.1 1.3
Had other major operations 0.1 0.1 0.2 0.2 -0.4
Forced vital capacity (FVC) 0.5 2.0 2.1 1.4 -1.5
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.7 0.8 0.9 -0.7
Ever unenthusiastic/disinterested for a whole week 1.2 1.4 1.7 -1.3 1.1
Qualifications: None of the above 5.5 11.7 12.5 -3.3 3.5
Financial difficulties in last 2 years 4.5 6.1 6.5 -2.5 2.4
Mouth/teeth dental problems 0.9 1.4 1.8 1.0 -1.4
Heart attack 0.2 0.3 0.5 0.7 -0.3
Allergy 1.9 4.3 4.5 2.0 -2.1
Pain all over the body in last month 1.2 1.2 1.4 -1.2 1.1
Diabetes (self-reported) 0.7 1.1 1.5 -1.2 0.8
Hayfever/allergic rhinitis (self-reported) 0.2 0.2 0.3 0.5 -0.5
Medication: Ramipril 3.0 3.9 4.4 2.1 -1.8
Medication: Simvastatin 0.2 0.3 0.4 0.6 -0.5
Fluid intelligence score 0.4 0.8 0.8 0.9 -0.9
Illnesses of siblings 2.5 3.5 3.9 1.8 -2.0
Neuroticism score 0.0 0.0 0.1 -0.1 0.3
Weight 3.4 16.6 17.4 -4.2 4.0
Impedance of arm (right) 3.3 15.2 16.4 4.0 -3.8
Arm fat percentage (right) 2.2 8.8 8.9 -3.0 3.0
Trunk fat-free mass 2.2 12.7 13.2 -3.6 3.5
Hip circumference 4.0 17.2 18.1 -4.3 4.0
Time employed in main current job 0.1 0.1 0.1 0.4 -0.1
Alcohol intake versus 10 years previously 1.1 1.7 2.1 -1.1 1.5
Father’s age at death 6.9 9.3 9.4 3.1 -3.0
Worrier / anxious feelings 0.0 0.0 0.0 0.2 -0.0
Frequency of tiredness / lethargy in last 2 weeks 2.3 3.8 3.9 -2.0 1.9
Falls in the last year 0.6 0.9 0.9 -0.9 1.0
Hair/balding pattern: Pattern 3 2.1 3.2 3.2 -1.8 1.8
Number of live births 0.4 0.6 0.8 -0.9 0.6
Forced expiratory volume in 1-second (FEV1) 0.4 1.2 1.3 1.1 -1.1
Pulse rate 0.7 1.2 1.4 1.0 -1.2
Happiness 0.8 0.9 1.1 -0.9 1.1
Noisy workplace 0.3 0.4 0.4 -0.5 0.7
Qualifications: A levels/AS levels or equivalent 1.0 2.2 2.4 1.5 -1.4
Serious illness, injury or assault of a close relative in last 2 years 2.7 3.2 3.4 -1.7 1.8
Mouth/teeth dental problems: Dentures 0.0 0.1 0.1 -0.1 0.3
Asthma 0.7 1.4 1.7 -1.0 1.3
Medication: Ibuprofen (e.g. Nurofen) 0.7 0.9 1.2 -1.1 0.8
Medication: Cholesterol lowering 0.7 1.1 1.3 0.9 -1.1
Depression (self-reported) 0.1 0.1 0.1 0.3 -0.2
Medication: Lansoprazole 0.4 0.4 0.4 -0.6 0.6
Prospective memory result 0.1 0.2 0.2 0.4 -0.4
Lung cancer (father) 11.7 13.7 14.4 -3.8 3.6
Illnesses of mother 0.0 0.0 0.0 0.2 -0.2
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 1.1 1.2 1.0 -1.1
Pulse wave Arterial Stiffness index 0.9 1.0 1.2 0.9 -1.1
Impedance of arm (left) 2.8 12.8 13.1 3.6 -3.5
Arm fat mass (right) 3.6 14.9 15.0 -3.9 3.9
Trunk predicted mass 2.3 13.3 13.8 -3.7 3.6
Standing height 0.0 0.1 0.2 -0.5 0.3
Length of working week for main job 0.0 0.0 0.0 0.2 0.1
Exposure to tobacco smoke at home 1.2 1.3 1.5 1.2 -1.0
Breastfed as a baby 1.8 2.2 2.7 1.3 -1.6
Tense / ‘highly strung’ 0.3 0.5 0.8 -0.5 0.9
Seen doctor (GP) for nerves, anxiety, tension or depression 0.0 0.1 0.1 -0.2 0.3
Hair/balding pattern: Pattern 4 0.0 0.0 0.0 -0.2 0.1
Birth weight of first child 2.6 4.7 5.4 -2.3 2.0
Peak expiratory flow (PEF) 0.0 0.0 0.0 -0.1 -0.1
Pulse wave reflection index 0.3 0.4 0.5 0.7 -0.6
Ever highly irritable/argumentative for 2 days 0.3 0.4 0.6 -0.7 0.4
Loud music exposure frequency 7.4 8.0 8.2 -2.9 2.8
Qualifications: O levels/GCSEs or equivalent 2.2 3.5 3.6 1.9 -1.9
Mouth/teeth dental problems: Bleeding gums 3.0 3.9 4.0 -1.9 2.0
Blood clot in the leg (DVT) 2.2 2.9 3.2 -1.8 1.6
Medication: Paracetamol 0.3 0.5 0.5 0.7 -0.7
Headache pain in last month 0.1 0.2 0.4 0.6 -0.3
Medication for cholesterol, blood pressure or diabetes 1.7 2.8 3.2 -1.5 1.8
Glaucoma (self-reported) 0.0 0.1 0.1 -0.3 -0.1
Gout (self-reported) 0.1 0.2 0.2 -0.5 0.3
Hypothyroidism/myxoedema (self-reported) 0.3 0.7 0.7 -0.9 0.7
Medication: Amlodipine 1.0 1.4 2.1 1.5 -0.8
Medication: Ventolin 100micrograms inhaler 0.1 0.1 0.1 0.3 -0.2
Birth weight 0.4 0.9 1.1 -1.1 0.9
Chronic bronchitis/emphysema (mother) 0.1 0.2 0.2 0.3 -0.5
High blood pressure (siblings) 0.0 0.0 0.0 0.1 0.1
Forced vital capacity (FVC), Best measure 0.5 2.0 2.1 1.4 -1.4
Body fat percentage 1.5 5.9 6.0 -2.4 2.4
Leg fat percentage (right) 1.1 4.1 4.2 -2.0 2.0
Arm fat-free mass (right) 2.8 14.3 15.2 -3.9 3.7
Exposure to tobacco smoke outside home 4.2 5.6 6.3 -2.5 2.2
Comparative body size at age 10 0.1 0.2 0.2 -0.4 0.5
Number of full brothers 6.7 8.4 9.8 -2.6 3.1
Worry too long after embarrassment 0.4 0.6 0.6 0.8 -0.8
Seen a psychiatrist for nerves, anxiety, tension or depression 0.1 0.2 0.2 0.4 -0.5
Wheeze or whistling in the chest in last year 2.1 3.8 4.1 -1.9 2.0
Number of children fathered 0.3 0.4 0.4 -0.6 0.5
Reason for reducing amount of alcohol drunk: Health precaution 0.0 0.0 0.0 -0.2 -0.0
Age at first live birth 5.6 10.0 10.6 3.3 -3.0
Pulse wave peak to peak time 0.8 1.0 1.2 -0.9 1.1
Health satisfaction 1.1 1.4 1.6 -1.2 1.1
Shortness of breath walking on level ground 8.6 10.2 10.9 -3.3 3.1
Qualifications: College or University degree 0.4 1.2 1.2 1.1 -1.1
Eye problems/disorders: None of the above 0.3 0.3 0.5 0.7 -0.4
Mouth/teeth dental problems: Loose teeth 1.3 1.5 1.5 -1.2 1.2
Emphysema/chronic bronchitis 0.5 0.5 0.5 -0.7 0.7
Medication for pain relief, constipation, heartburn 0.0 0.1 0.1 0.4 0.0
Neck or shoulder pain in last month 1.3 1.9 1.9 -1.4 1.4
Medication: Blood pressure 0.2 0.3 0.3 0.5 -0.6
Angina (self-reported) 0.9 1.2 1.3 1.1 -1.1
Migraine (self-reported) 0.1 0.2 0.2 0.5 -0.4
Medication: Ibuprofen 1.0 1.2 1.7 -1.3 0.8
Medication: Allopurinol 0.5 0.6 0.7 -0.8 0.7
Medication: Omeprazole 2.6 3.1 3.6 -1.9 1.6
Medication: Seretide 50 evohaler 0.0 0.0 0.0 -0.1 -0.2
Mean time to correctly identify matches 4.0 7.6 7.8 2.7 -2.8
Heart disease (mother) 2.0 2.4 2.5 -1.5 1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.7 0.7 -0.8 0.8
Whole body fat mass 2.3 9.5 9.5 -3.1 3.1
Leg fat mass (right) 2.9 11.4 11.4 -3.4 3.4
Arm predicted mass (right) 2.9 14.8 15.7 -4.0 3.7
Pulse rate, automated reading 1.5 4.8 5.0 2.1 -2.2
Alcohol intake frequency. 5.7 13.2 14.5 -3.5 3.8
Comparative height size at age 10 0.6 3.5 3.7 -1.9 1.8
Number of full sisters 2.7 3.3 3.4 1.9 -1.8
Suffer from ‘nerves’ 1.0 1.5 2.1 -1.0 1.4
Overall health rating 3.9 8.3 8.7 -2.8 2.9
Chest pain or discomfort 0.9 1.3 1.4 -1.1 1.2
Had major operations 1.0 1.1 1.2 -1.1 1.0
Age at last live birth 4.3 6.3 6.7 2.6 -2.4
Family relationship satisfaction 2.6 3.2 3.2 -1.8 1.8
Leg pain on walking 1.0 1.2 1.3 -1.2 1.1
Qualifications: NVQ or HND or HNC or equivalent 1.5 1.8 2.0 1.3 -1.4
Commuting to job workplace: Car/motor vehicle 0.0 0.0 0.1 0.0 0.3
Illness, injury, bereavement, stress in last 2 years 3.3 4.0 4.4 2.1 -1.9
Medication: Aspirin 0.2 0.3 0.4 0.4 -0.7
Supplements: Vitamin C 0.3 0.3 0.3 0.6 -0.5
Knee pain experienced in last month 1.0 1.5 1.6 -1.3 1.2
Hypertension (Self-reported) 2.0 5.7 5.8 2.4 -2.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.1 0.1 -0.4 0.1
Illnesses of father: Heart disease 0.1 0.2 0.4 -0.0 0.6
Illnesses of siblings: Diabetes 9.3 11.5 11.8 -3.4 3.3
Smoking status: Previous 0.0 0.0 0.0 -0.0 0.1
Forced expiratory volume in 1-second (FEV1), predicted 0.9 1.8 1.8 1.3 -1.3
Whole body fat-free mass 2.7 15.3 15.9 -4.0 3.8
Leg fat-free mass (right) 3.1 16.8 17.7 -4.2 4.0
Arm fat percentage (left) 2.6 10.3 10.6 -3.3 3.2
Average weekly red wine intake 0.2 0.4 0.5 0.5 -0.7
Handedness (chirality/laterality): Left-handed 1.2 1.4 2.1 1.4 -0.9
Mood swings 0.2 0.4 0.5 -0.7 0.6
Loneliness, isolation 0.0 0.0 0.0 -0.0 0.2
Long-standing illness, disability or infirmity 3.1 4.8 5.3 -2.3 2.1
Ever had bowel cancer screening 0.7 0.9 1.1 0.8 -1.0
Diabetes diagnosed by doctor 0.5 0.8 1.2 -1.1 0.6
Ever had stillbirth, spontaneous miscarriage or termination 0.4 0.4 0.6 0.8 -0.6
Friendships satisfaction 0.8 1.0 1.2 -1.0 1.1
Qualifications: nursing, teaching 0.0 0.0 0.0 -0.1 0.1
Commuting to job workplace: Walk 0.1 0.1 0.1 0.3 -0.3
Eye problems/disorders: Cataract 0.0 0.0 0.1 0.0 -0.3
Mouth/teeth dental problems: Mouth ulcers 0.0 0.1 0.1 0.3 -0.2
Medication for cholesterol 0.5 0.7 1.1 -1.0 0.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.5 0.6 0.8 0.9 -0.7
Back pain experienced in last month 0.1 0.1 0.2 -0.4 0.3
Mineral and other dietary supplements 2.6 3.5 3.5 -1.9 1.9
Breast cancer (self-reported) 0.6 0.7 0.7 -0.9 0.8
Asthma (self-reported) 0.9 1.8 2.1 -1.2 1.4
Osteoporosis (self-reported) 2.1 2.6 3.2 -1.4 1.8
Osteoarthritis (self-reported) 0.3 0.4 0.4 -0.6 0.7
Medication: Aspirin 0.5 0.6 0.8 0.7 -0.9
Medication: Gliclazide 0.1 0.1 0.2 -0.4 0.2
Illnesses of father: None of the above (group 1) 1.8 2.2 2.9 1.2 -1.7
Smoking status: Current 0.2 0.3 0.4 -0.4 0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.6 0.7 0.8 -0.7
Whole body water mass 2.6 15.1 15.8 -4.0 3.8
Leg predicted mass (right) 3.2 17.1 18.0 -4.2 4.0
Arm fat mass (left) 4.1 16.8 17.0 -4.1 4.1
Number of self-reported non-cancer illnesses 0.2 0.3 0.4 0.4 -0.6
Average weekly champagne plus white wine intake 0.3 0.4 0.6 -0.8 0.4
Miserableness 1.1 1.9 2.1 -1.4 1.3
Guilty feelings 0.0 0.1 0.1 -0.3 0.2
Wears glasses or contact lenses 1.2 1.3 1.4 1.1 -1.2
Ever taken oral contraceptive pill 0.4 0.5 0.5 -0.7 0.7
Hearing aid user 1.9 2.2 2.4 -1.4 1.6
Mother’s age at death 0.3 0.3 0.4 0.5 -0.6
Financial situation satisfaction 0.1 0.1 0.1 -0.4 0.2
Tinnitus: Yes, now most or all of the time 2.1 2.4 2.5 -1.5 1.6
Commuting to job workplace: Public transport 0.0 0.0 0.1 -0.0 -0.3
Eye problems/disorders: Glaucoma 0.2 0.3 0.5 -0.7 0.3
Medication: Blood pressure 1.8 3.4 3.6 1.9 -1.8
Pain type(s) experienced in last month: Hip pain 1.3 1.6 1.6 -1.3 1.2
Supplements: Fish oil (including cod liver oil) 3.2 4.1 4.4 2.0 -2.1
High cholesterol (Self-reported) 0.3 0.6 0.6 0.7 -0.7
Medication: Bendroflumethiazide 2.1 3.2 3.4 1.7 -1.9
Medication: Paracetamol 0.0 0.0 0.1 0.2 -0.2
Medication: Lisinopril 0.9 1.2 1.7 0.8 -1.3
Medication: Atorvastatin 0.0 0.0 0.1 0.1 -0.2
Illnesses of father: High blood pressure 0.0 0.0 0.0 0.2 -0.2
Alcohol drinker status: Never 7.6 9.0 9.2 -3.0 3.0
Ever smoked 0.0 0.0 0.0 0.1 0.1
Basal metabolic rate 3.1 16.9 17.6 -4.2 4.0
Leg fat percentage (left) 1.5 5.5 5.7 -2.4 2.3
Arm fat-free mass (left) 2.6 13.2 13.9 -3.7 3.5
Number of operations (self-reported) 0.1 0.1 0.1 -0.3 0.4
Average weekly beer plus cider intake 0.4 0.5 0.7 0.6 -0.8
Irritability 0.3 0.5 0.7 0.9 -0.5
Risk taking 0.8 1.1 1.3 -1.0 1.1
Ever had prostate specific antigen (PSA) test 0.4 0.5 0.7 0.5 -0.8
Fractured/broken bones in last 5 years 0.3 0.4 0.6 -0.5 0.8
Age started oral contraceptive pill 1.1 1.4 1.5 1.2 -1.1
Diastolic blood pressure, automated reading 3.7 11.3 12.2 3.5 -3.2
Ever depressed for a whole week 1.7 2.0 2.8 -1.7 1.1
Unable to work because of sickness or disability 1.5 2.0 2.5 -1.2 1.6
Commuting to job workplace: Cycle 2.4 2.9 3.3 1.8 -1.6
Myopia 1.0 1.4 1.5 1.2 -1.2
Vascular/heart problems diagnosed by doctor 2.7 7.3 7.5 -2.7 2.7
Cholesterol lowering medication 0.5 0.7 0.9 0.9 -0.8
Medication: Omeprazole (e.g. Zanprol) 1.5 1.8 2.2 -1.5 1.2
Pain experienced in last month 1.1 1.8 1.9 1.3 -1.4
Supplements: Calcium 0.0 0.0 0.1 -0.0 0.3
Basal cell carcinoma (self-reported) 0.4 0.5 0.6 0.8 -0.6
Heart attack/myocardial infarction (self-reported) 0.1 0.1 0.2 0.5 -0.1
Deep venous thrombosis (DVT) (self-reported) 2.5 3.2 3.6 -1.9 1.7
Heart disease (siblings) 0.3 0.4 0.4 -0.6 0.7
Alcohol drinker status: Previous 1.3 1.5 1.7 -1.1 1.3
Pack years of smoking 1.7 2.4 2.9 -1.4 1.7
Impedance of whole body 3.8 19.2 20.2 4.5 -4.3
Leg fat mass (left) 3.2 12.7 12.9 -3.6 3.5
Arm predicted mass (left) 2.5 12.9 13.4 -3.7 3.5