Hub : Genes

WDR91

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0450	0.0210	7.0e-03	0.023	0.023	0.035	0.020	0.030	8.0e-04	6.7e-04	3.4e-05	1.4e-03	1.4e-04
2	GTEx	Adrenal Gland	0.3357	0.0780	4.4e-07	0.169	NA	0.072	NA	0.115	1.1e-06	NA	1.4e-03	NA	6.5e-05
3	GTEx	Cells EBV-transformed lymphocytes	0.1390	0.0570	4.9e-03	0.148	NA	0.020	NA	0.111	1.5e-05	NA	7.5e-02	NA	1.8e-04
4	GTEx	Cells Transformed fibroblasts	0.0890	0.0310	4.1e-04	0.015	NA	0.023	NA	0.023	2.6e-02	NA	7.3e-03	NA	7.4e-03
5	GTEx	Esophagus Mucosa	0.1410	0.0360	2.2e-07	0.106	NA	0.120	NA	0.101	1.6e-07	NA	2.1e-08	NA	3.1e-07
6	GTEx	Lung	0.1250	0.0422	1.3e-04	0.078	NA	0.046	NA	0.072	1.4e-06	NA	1.8e-04	NA	3.6e-06
7	GTEx	Skin Not Sun Exposed Suprapubic	0.0840	0.0380	7.9e-03	0.014	NA	0.013	NA	0.005	5.3e-02	NA	5.9e-02	NA	1.7e-01
8	GTEx	Skin Sun Exposed Lower leg	0.0850	0.0310	4.1e-04	0.040	NA	0.019	NA	0.029	2.6e-04	NA	8.7e-03	NA	1.9e-03
9	GTEx	Stomach	0.1530	0.0550	5.8e-04	0.104	NA	0.062	NA	0.085	1.2e-05	NA	6.6e-04	NA	7.2e-05
10	GTEx	Thyroid	0.1100	0.0400	1.6e-03	-0.004	NA	0.010	NA	-0.004	9.0e-01	NA	5.1e-02	NA	9.3e-01
11	METSIM	Adipose	0.0796	0.0219	4.4e-10	0.075	0.068	0.075	0.071	0.085	2.7e-11	2.3e-10	2.1e-11	7.4e-11	1.1e-12
12	NTR	Blood	0.0411	0.0109	1.1e-11	0.047	0.037	0.050	0.032	0.028	6.0e-15	5.7e-12	6.9e-16	1.0e-10	1.9e-09
13	ROSMAP	Brain Pre-frontal Cortex	0.0667	0.0206	1.5e-06	0.076	0.049	0.054	0.061	0.070	5.7e-10	6.1e-07	1.6e-07	3.0e-08	2.6e-09
14	YFS	Blood	0.0259	0.0090	7.5e-06	0.009	0.018	0.022	0.018	0.018	5.4e-04	1.1e-06	5.7e-08	1.2e-06	7.9e-07
15	TCGA	Cervical Squamous Cell Carcinoma	0.0720	0.0380	2.6e-03	0.024	0.047	0.024	NA	0.024	2.2e-02	2.4e-03	2.4e-02	NA	2.3e-02
16	TCGA	Head and Neck Squamous Cell Carcinoma	0.0260	0.0168	6.4e-03	-0.002	0.006	-0.001	NA	-0.002	6.7e-01	5.7e-02	4.9e-01	NA	9.5e-01
17	TCGA	Kidney Renal Clear Cell Carcinoma	0.1987	0.0789	8.4e-07	0.027	0.052	0.061	NA	0.020	4.1e-04	1.6e-06	2.1e-07	NA	2.1e-03
18	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1620	0.0590	9.0e-13	0.224	0.214	0.231	NA	0.256	5.6e-13	1.9e-12	2.0e-13	NA	7.5e-15
19	TCGA	Brain Lower Grade Glioma	0.0497	0.0323	1.3e-03	0.022	0.023	0.018	NA	0.026	1.3e-03	1.2e-03	3.3e-03	NA	5.8e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Bipolar Disorder (2018)	1.9	3.0	8.3	-2.6	0.1	2.3	-1.6	0.9	0.8	2.8	2.9	0.6	2.0	0.8	2.5	-0.3	1.8	2.1	2.2	-0.2	-1.0	-0.0
Bipolar Disorder or Schizophrenia	2.0	4.9	13.6	-2.3	0.4	2.5	-2.7	2.1	1.9	3.4	3.7	1.4	3.2	1.5	3.0	-0.2	1.7	1.9	2.9	-0.7	-1.4	0.6
Depressed Affect (Nagel 2018)	0.1	0.3	1.8	0.7	-0.0	-0.5	-0.7	-0.0	0.1	-0.3	-0.4	0.1	1.4	0.0	-0.5	0.3	1.1	-0.4	-0.4	0.6	0.1	0.5
Depression (Nagel 2018)	0.2	0.3	1.1	0.5	-0.4	0.1	-0.2	-0.4	-0.1	0.1	0.5	-0.6	1.0	-1.1	-0.1	-0.3	-0.9	0.2	-0.5	-0.0	0.4	-0.5
Intelligence (Savage-Jansen 2018)	0.8	2.4	7.0	-0.4	2.1	1.1	-2.6	2.1	2.1	1.3	1.0	1.3	-0.7	1.4	0.9	2.0	1.0	-0.1	1.5	-1.9	-2.1	0.9
Neuroticism (Nagel 2018)	0.3	0.7	1.7	1.2	0.7	-0.3	-1.2	0.6	0.9	0.0	-0.1	1.1	1.2	0.7	-0.3	1.3	0.8	-0.7	0.2	0.6	-0.9	0.8
Schizophrenia (2018)	1.1	2.3	6.1	-0.8	0.5	1.4	-2.2	1.9	1.8	2.0	2.4	1.3	2.5	1.2	1.8	0.1	0.8	0.8	1.9	-0.7	-1.0	0.8
Schizophrenia vs Biploar Disorder	1.0	1.3	8.7	3.0	0.1	-1.6	1.0	-0.1	0.8	-1.5	-1.0	0.5	0.4	0.5	-1.1	0.6	-0.7	-1.8	-1.0	0.5	0.4	1.2
Worry (Nagel 2018)	0.7	1.6	4.1	1.5	1.3	-0.1	-1.0	1.4	1.7	0.2	0.1	1.9	0.9	1.7	-0.2	2.0	0.7	-1.4	0.7	0.4	-1.5	1.8
Alzheimer’s Disease (in mother)	0.3	0.4	1.4	-0.8	-0.6	0.0	0.7	-0.6	-0.8	0.1	-0.1	-0.6	-1.2	-0.2	0.2	-1.0	0.9	0.8	-0.3	0.5	0.5	-0.6
Alzheimer’s Disease (in father)	0.3	0.3	1.1	0.5	0.5	-0.5	1.1	0.1	0.1	-0.5	-0.7	0.3	0.3	0.9	-0.6	0.4	0.7	-1.0	0.1	-0.2	-0.2	1.0
Alzheimer’s Disease (including proxy)	0.8	1.2	2.8	-0.5	-1.0	-1.0	1.5	-1.4	-1.7	-1.1	-1.5	-1.4	-0.9	-0.7	-0.7	-1.3	0.3	-0.2	-1.3	0.9	1.5	-0.3
Crohns Disease (2017)	0.5	1.0	3.0	1.0	-0.7	-1.5	0.1	-0.1	-0.9	-1.2	-1.4	-0.3	0.7	-0.2	-1.5	0.1	-1.7	-1.1	-1.2	1.4	0.7	0.2
Irritable Bowel Disease (IBD)	0.5	1.1	4.4	1.7	0.2	-1.6	0.8	0.2	-0.4	-1.2	-1.1	0.9	-0.0	0.8	-1.2	1.2	-0.5	-2.1	-0.6	0.5	0.0	1.5
Ulcerative Colitis (UC)	1.0	1.8	7.2	2.0	1.1	-1.5	1.7	0.0	-0.0	-1.2	-0.9	1.2	-0.9	1.5	-1.0	1.7	0.6	-2.7	-0.2	-0.1	-0.3	2.3
Major Depression (MDD)	0.4	0.5	1.3	0.2	0.9	0.3	0.8	0.5	-0.0	0.8	0.7	0.6	0.7	1.1	0.6	0.7	1.1	-0.5	1.0	0.0	-0.9	1.0
Reaction Time	0.8	1.5	3.3	-1.0	0.9	1.7	-0.6	1.5	1.7	1.8	1.8	1.2	0.3	0.6	1.7	0.7	0.5	1.0	1.6	-1.0	-1.5	0.0
Verbal and Numeric Reasoning (VNR)	0.1	0.2	0.7	-0.7	0.7	-0.0	-0.9	0.5	0.3	0.0	-0.3	0.0	0.3	0.3	-0.3	0.7	-0.2	-0.4	0.1	-0.0	-0.4	0.3
Breast Cancer	0.9	2.2	5.6	1.8	2.4	1.1	-1.4	1.3	1.7	1.3	1.1	1.5	-0.2	2.1	1.1	1.7	0.8	-0.2	1.9	-0.7	-2.0	1.3
Ovarian Cancer	0.7	0.9	3.8	1.7	0.1	-1.2	2.0	-1.2	-0.5	-1.1	-0.9	-0.8	0.4	-0.1	-0.8	-0.1	0.4	-0.9	-1.1	0.2	1.0	0.7
Prostate Cancer	0.4	0.6	1.3	-0.1	-0.9	-1.1	0.8	-0.8	-0.4	-1.2	-1.0	-0.5	0.7	-0.5	-1.0	-0.7	0.6	-0.0	-1.1	0.5	1.0	-0.3
Age at First Birth	0.3	0.4	1.0	-0.8	-0.4	0.4	-0.3	-0.9	-0.6	0.1	0.4	-0.8	-0.9	-0.5	0.9	-0.7	-0.4	1.0	0.3	-0.4	0.3	-0.5
Bipolar Disorder (2011)	2.8	2.7	7.7	-2.1	-0.6	2.4	-2.0	0.4	-0.0	2.7	2.8	-0.3	1.5	-0.8	2.6	-1.0	0.4	2.5	1.5	0.3	-0.3	-1.2
Body Mass Index (BMI) (2010)	1.3	1.8	4.1	-1.2	-1.9	1.5	-1.4	-0.8	-0.9	1.2	1.1	-1.2	-1.6	-1.5	1.8	-1.6	0.6	2.0	0.1	-1.2	0.7	-1.8
Coronary Artery Disease (CAD)	0.5	0.6	2.9	-0.9	0.2	1.3	-1.7	0.7	0.3	1.1	0.8	0.6	-0.3	-0.2	1.1	0.3	-0.2	0.6	0.6	-0.4	-0.8	-0.5
Crohns Disease (2012)	0.4	0.6	2.3	0.3	0.0	0.5	-1.5	0.9	0.0	1.1	0.8	0.9	1.1	0.8	0.7	0.8	-0.3	0.1	0.8	1.0	-0.9	0.3
Mean Putamen Volume	0.4	0.5	1.8	0.1	-0.4	-0.1	-0.1	-1.1	-0.2	-0.1	0.2	-0.8	0.3	-1.2	0.1	-0.9	-1.3	0.4	-0.8	0.5	0.9	-1.2
Fasting Glucose	1.0	1.2	2.6	0.1	-1.3	0.1	0.5	-1.6	-1.4	0.0	0.3	-1.3	-0.6	-1.5	0.6	-1.6	-1.5	0.8	-0.6	1.1	1.3	-1.4
HbA1C	0.5	0.5	2.0	-0.9	-0.8	0.6	-0.5	-0.3	-0.4	0.3	0.6	-1.4	-0.9	-0.8	0.7	-1.3	0.1	0.8	-0.1	-0.3	0.9	-0.5
HDL Cholesterol	2.0	3.3	10.0	3.0	1.3	-2.5	2.1	-0.0	0.2	-2.3	-2.4	1.0	1.8	1.5	-2.6	1.4	-0.3	-3.2	-0.8	0.5	-0.1	2.0
LDL Cholesterol	0.7	1.2	2.8	-0.5	0.7	0.7	-1.7	1.6	1.1	0.8	0.7	1.7	-1.5	0.8	0.8	1.3	1.3	0.3	1.1	0.1	-1.4	0.3
Lupus	0.7	1.0	2.6	0.4	-0.2	-1.5	-0.3	0.2	-0.2	-1.6	-1.6	0.2	0.2	0.8	-1.6	0.5	1.2	-1.5	-0.8	-1.2	0.4	1.5
Neuroticism (2016)	0.4	0.6	2.2	0.9	0.1	-0.6	0.0	-0.0	0.3	-0.7	-0.5	-0.6	-1.2	-0.0	-0.5	0.4	1.5	-1.1	-0.7	-1.4	0.2	0.8
Primary Biliary Cirrhosis	1.0	1.5	4.4	-0.6	-0.2	1.6	-2.0	0.5	-0.5	1.9	2.1	-0.4	0.0	0.3	2.0	-0.7	1.6	1.1	1.3	1.5	-0.2	-0.1
Rheumatoid Arthritis	2.1	3.0	8.6	1.8	1.4	-2.3	1.9	0.7	1.1	-2.1	-1.9	1.6	-0.6	1.7	-2.2	2.1	-1.5	-2.9	-0.7	0.8	-0.8	2.2
Schizophrenia (2014)	2.0	4.4	12.3	-0.8	0.8	2.5	-2.5	2.5	2.2	3.1	3.5	1.6	2.6	1.6	2.9	0.3	1.2	1.4	2.9	-1.0	-1.8	0.7
Triglycerides	1.8	2.9	8.5	-2.1	-2.6	-0.2	-0.1	-1.9	-2.0	-0.5	-0.9	-2.1	-1.2	-2.9	-0.6	-2.1	-0.3	1.5	-1.6	0.7	2.1	-2.6
Type 2 Diabetes (T2D) (2012)	0.5	0.5	1.7	-0.9	-0.3	0.8	-0.4	-0.2	0.2	1.0	1.2	-0.2	-1.3	-0.4	1.2	-0.5	0.0	0.9	0.3	-1.0	0.1	-0.5
Ulcerative Colitis	1.4	2.0	7.3	1.9	1.2	-1.8	1.4	0.3	-0.1	-1.1	-0.8	1.2	-0.5	1.7	-1.1	1.7	0.5	-2.7	-0.4	0.9	-0.2	2.7
Blood Eosinophil Count	1.8	13.8	24.6	-0.9	3.1	4.7	-4.3	5.0	4.2	4.9	4.6	3.5	-3.4	2.6	4.4	2.7	-3.1	1.6	4.7	-3.1	-4.9	0.2
Blood Platelet Count	0.5	5.5	30.1	0.2	-0.4	-3.4	2.0	-0.5	-0.9	-3.0	-2.9	-0.8	-3.0	-0.3	-3.1	-0.0	-5.5	-2.6	-2.8	1.7	1.7	1.1
Blood Red Count	1.4	13.7	30.1	3.5	5.4	-3.1	2.6	2.9	5.3	-2.7	-2.2	4.5	1.4	5.1	-3.3	4.9	-0.7	-5.5	0.7	-2.0	-3.2	5.0
Blood White Count	0.5	3.5	22.8	-2.1	-1.7	0.0	1.3	-0.5	0.3	-0.4	-0.4	-1.0	-2.8	-2.7	-0.5	-1.1	-4.8	1.0	-1.7	-1.7	0.9	-2.9
Heel T-Score	0.2	1.8	6.2	-1.0	-0.6	1.4	-1.0	-0.6	-0.5	1.1	1.0	-1.9	-2.5	-1.5	1.0	-1.4	-0.8	1.8	0.1	-1.0	0.4	-2.5
BMI	0.4	2.4	7.5	-0.6	-0.8	2.7	-1.5	0.1	1.2	2.4	2.2	-0.0	-0.4	-1.0	2.5	-0.6	0.3	2.3	1.0	-2.5	-0.6	-1.7
Height	0.2	3.5	26.4	2.8	1.3	-0.2	-1.8	-0.1	0.1	0.8	1.3	-1.4	5.1	2.2	1.0	0.7	1.3	-1.1	1.0	2.0	0.2	2.9
Waist Hip Ratio (WHR)	0.8	3.6	9.9	-1.4	0.1	2.9	-3.1	2.6	0.4	3.1	2.8	1.1	0.9	-0.2	2.5	0.0	-1.1	2.2	2.1	-0.3	-1.6	-1.3
Systolic Blood Pressure	1.8	9.2	18.3	-3.4	-4.3	-2.2	2.4	-3.2	-3.1	-2.4	-2.8	-2.8	2.5	-3.9	-2.4	-3.8	-1.3	0.9	-3.7	2.7	3.8	-3.7
Smoking Status	0.4	1.0	4.2	1.0	-0.2	-1.1	1.3	-0.6	-1.0	-0.8	-0.7	-0.2	1.9	-0.2	-0.9	-0.0	-1.4	-1.2	-0.8	2.1	0.6	0.3
Allergy or Eczema	2.4	6.2	15.2	1.1	3.9	0.8	-1.0	3.2	2.8	1.0	0.8	3.7	2.5	3.0	0.2	3.8	1.8	-1.8	2.9	-1.1	-3.6	2.6
Cardiovascular Disease	2.1	7.0	16.3	-1.9	-4.0	-1.0	0.6	-3.4	-3.5	-1.0	-1.8	-3.6	1.2	-3.5	-1.2	-3.6	-2.2	1.2	-3.3	1.9	3.8	-2.8
Hypothyroidism (self reported)	1.8	4.1	9.5	-0.5	1.8	2.7	-1.4	2.2	1.9	2.5	2.3	2.3	0.2	1.8	2.4	1.7	1.8	1.0	3.1	-2.6	-2.7	0.9
Respiratory disease	0.3	0.7	1.9	-0.8	0.6	0.6	-1.3	1.4	0.0	0.7	0.5	0.7	0.2	1.0	0.4	0.4	1.4	-0.0	1.2	-0.1	-0.7	0.9
Type 2 Diabetes (T2D) (2018)	0.2	0.3	1.5	1.2	0.2	-0.1	-0.7	1.0	1.1	-0.0	-0.1	-0.0	0.4	0.1	0.2	0.5	-1.0	-0.7	-0.1	-0.3	-0.5	0.1
Lung FEV1/FVC ratio	1.9	9.4	30.1	3.0	4.9	-1.0	-0.3	3.2	5.5	-1.1	-0.7	3.9	-1.9	3.2	-1.1	4.6	0.7	-3.3	1.1	-4.1	-3.6	2.9
Lung FVC	0.7	3.8	13.4	-3.7	-2.3	1.8	-0.2	-1.6	-1.2	1.4	1.7	-2.4	-0.0	-2.1	1.8	-2.6	0.8	3.3	0.3	0.2	1.1	-2.8
Neuroticism	0.4	0.9	2.1	1.2	1.1	0.6	-1.4	0.9	0.9	0.8	0.4	1.3	0.9	1.0	0.5	1.3	0.8	-0.3	0.7	0.2	-1.3	0.7
Chronotype (morning person)	0.9	2.2	6.2	-1.9	-2.5	-0.5	-0.3	-0.9	-1.6	-0.1	-0.1	-1.6	0.6	-2.2	-0.4	-1.7	-1.6	1.2	-1.4	2.0	1.8	-1.9
Hair Pigment	0.1	2.8	7.1	0.4	-2.2	-1.4	1.4	-1.9	-2.7	-1.5	-1.9	-1.4	1.2	-1.9	-1.5	-1.6	-1.7	-0.2	-2.1	1.1	2.2	-1.2
Tanning	0.2	2.4	6.5	1.9	1.6	-1.9	1.9	0.5	0.9	-1.8	-1.3	1.2	-0.3	2.1	-1.8	1.8	0.6	-2.5	0.0	0.5	-0.7	2.6
Hand grip strength (left)	0.0	0.1	0.3	0.0	-0.2	0.1	-0.3	-0.0	-0.1	-0.1	0.1	-0.5	-0.5	0.1	0.3	-0.4	0.5	0.5	0.4	-0.4	0.2	-0.0
Number of treatments/medications taken	0.6	1.1	4.3	0.3	0.9	0.6	-1.0	1.2	1.1	1.1	1.4	1.4	2.1	1.2	0.9	0.8	0.7	-0.2	1.1	0.2	-0.9	1.2
Average weekly spirits intake	0.6	0.8	2.8	0.7	1.1	-1.2	-0.4	0.9	1.0	-0.7	-0.7	0.7	1.7	0.6	-1.2	1.0	-0.6	-1.2	-0.2	0.3	-0.3	0.7
Sensitivity / hurt feelings	0.3	0.5	2.9	-0.0	-0.8	-0.6	-0.8	0.1	0.2	-0.5	-0.8	0.5	1.7	-0.9	-1.0	0.2	-0.5	0.2	-1.0	0.4	0.0	-1.1
Frequency of depressed mood in last 2 weeks	0.4	0.5	3.5	1.9	0.6	-0.2	-0.6	0.5	0.8	0.1	0.7	0.1	-0.0	0.6	0.3	0.7	0.6	-0.9	-0.1	-0.2	-0.3	1.4
Hearing difficulty/problems: Yes	0.3	0.5	3.1	-1.8	-0.0	-0.0	0.9	-0.4	0.3	0.0	0.0	-0.2	1.5	-0.3	-0.3	-0.6	0.8	0.5	-0.2	0.5	0.1	-0.8
Relative age of first facial hair	0.7	1.5	4.2	1.6	1.3	-1.9	1.0	0.0	0.1	-1.3	-1.2	0.5	1.1	1.2	-1.8	1.2	-0.2	-1.8	-0.5	2.1	-0.3	1.3
Other serious medical condition/disability diagnosed by doctor	1.6	2.1	4.5	-0.5	1.0	1.9	-2.1	1.7	1.7	2.1	1.9	1.5	0.9	0.5	1.7	1.0	0.6	1.2	1.9	-0.9	-1.9	-0.3
Ever used hormone-replacement therapy (HRT)	1.9	2.4	5.2	0.1	1.5	1.4	-2.3	2.0	1.8	1.6	1.8	1.9	-1.3	1.5	1.6	1.3	0.2	-0.1	1.8	-2.0	-1.8	1.1
Ever had hysterectomy (womb removed)	1.0	1.1	5.3	-0.7	1.2	0.8	0.4	1.3	1.3	0.7	0.8	1.3	-0.8	1.0	0.4	0.9	1.2	-0.1	1.2	-2.3	-1.3	0.5
Systolic blood pressure, automated reading	0.4	1.3	3.2	-1.5	-1.8	-0.8	1.0	-0.8	-1.0	-0.8	-1.0	-0.7	0.8	-1.4	-1.0	-1.4	-1.0	0.6	-1.4	-0.4	1.1	-1.7
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	2.5	1.4	0.6	-0.6	0.8	0.6	1.6	-0.3	-0.5	1.2	1.2	0.5	-0.4	1.3	-0.7	-1.2	0.1	-0.6	-1.0	0.0
Angina	0.5	0.6	1.9	0.7	0.3	-1.1	0.4	0.5	0.4	-0.8	-0.5	0.3	1.2	0.5	-0.9	0.8	-1.3	-1.4	-0.4	0.8	-0.1	1.0
Medication for hormone replacement therapy	1.8	2.0	5.0	2.2	1.9	0.5	-0.1	1.6	1.6	0.7	1.1	1.9	-0.6	1.6	0.6	1.9	0.9	-1.1	1.4	-1.4	-1.6	1.9
Vitamin and mineral supplements	0.7	1.0	2.4	-0.2	-1.2	-0.7	0.3	-1.2	-0.7	-0.9	-1.6	-1.1	-0.0	-1.2	-1.3	-0.8	-1.0	0.3	-1.3	0.8	0.9	-1.3
Supplements: Zinc	0.6	0.7	1.8	0.3	0.6	0.8	-0.9	1.1	0.1	1.0	1.4	0.8	-0.6	0.7	1.2	0.6	0.9	0.3	1.0	-0.6	-0.9	0.5
Medication: Co-codamol	0.7	0.8	2.0	-0.3	1.1	1.2	-0.8	0.5	1.4	1.3	1.2	1.0	1.0	0.2	0.8	0.7	-0.4	0.4	1.2	-0.2	-1.0	-0.0
Medication: Metformin	1.2	1.7	4.8	1.5	1.1	1.0	-1.8	1.5	2.2	1.1	1.1	1.2	-0.7	1.0	1.2	1.4	0.5	-0.5	1.4	-1.6	-1.7	0.6
Diabetes (father)	0.4	0.5	1.5	0.5	0.6	-0.5	0.5	0.6	0.6	-0.4	-0.6	1.2	-0.2	0.7	-0.8	1.1	-0.6	-0.8	0.2	-0.7	-0.8	0.6
Diabetes (mother)	0.6	0.7	2.1	0.8	1.1	0.5	0.0	1.0	0.7	0.3	0.2	0.7	-0.2	1.3	0.4	0.6	1.1	-0.7	1.0	-1.5	-1.0	1.2
Severe depression (siblings)	1.1	1.2	3.9	1.3	1.2	1.0	-0.3	1.4	1.5	0.9	0.5	2.0	0.3	1.0	0.5	1.4	-0.7	0.1	1.2	-1.0	-1.7	0.1
Pack years adult smoking proportion	1.9	2.9	9.4	-3.1	-1.2	2.2	0.4	-0.5	-1.5	2.0	2.5	-1.2	-1.7	-1.6	2.3	-1.5	-0.2	2.7	1.0	-0.7	0.4	-1.9
Impedance of leg (right)	0.3	1.5	10.0	-1.2	0.7	0.4	-1.6	0.9	0.1	1.0	1.5	0.8	3.2	0.4	0.8	0.1	0.7	0.5	1.0	2.4	-0.4	0.4
Leg fat-free mass (left)	0.2	1.0	4.5	1.0	-1.4	0.7	-0.6	-1.4	-1.0	0.6	0.4	-2.1	-0.8	-1.0	0.9	-1.2	0.2	1.0	-0.5	-0.9	1.1	-0.7
Trunk fat percentage	0.8	3.1	10.7	0.3	-0.3	3.3	-1.9	-0.2	0.7	3.0	2.5	-0.7	-1.9	-1.1	3.0	-0.7	-0.3	2.4	1.2	-2.1	-0.7	-1.7
Hand grip strength (right)	0.1	0.2	0.5	-0.7	0.1	0.3	-0.7	0.2	0.1	0.3	0.5	-0.3	-0.7	0.0	0.3	-0.4	0.2	0.7	0.4	-0.4	0.1	-0.3
Townsend deprivation index at recruitment	1.2	1.7	4.9	0.5	1.7	1.4	-0.2	1.5	1.2	1.4	1.1	1.9	-0.9	1.0	1.3	1.9	0.9	-0.2	1.5	-0.9	-2.2	0.4
Current tobacco smoking	0.4	0.6	1.7	-0.8	0.6	1.3	0.3	0.8	-0.2	1.2	1.3	0.5	-0.2	0.1	1.3	0.3	0.2	0.7	1.0	-0.1	-0.9	-0.4
Average weekly fortified wine intake	0.8	1.0	1.9	-1.2	-1.4	-0.1	0.3	-1.1	-1.1	-0.1	-0.1	-1.3	0.2	-1.3	-0.5	-1.3	-1.0	1.1	-0.8	1.2	1.2	-1.2
Maternal smoking around birth	0.3	0.4	2.9	0.8	0.4	1.0	-0.0	0.5	0.5	0.7	0.6	-0.2	-0.6	-0.0	0.6	0.0	1.1	0.2	0.3	-1.7	-0.3	0.2
Fed-up feelings	0.4	0.7	4.5	1.2	0.3	-1.0	0.1	0.1	-0.2	-0.7	-0.6	0.1	1.0	0.5	-0.7	0.5	2.1	-1.1	-0.6	0.5	0.2	1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	2.6	-0.3	-1.4	-0.5	0.3	-1.0	-1.0	-0.4	0.1	-1.4	0.7	-1.6	-0.3	-1.2	-1.1	0.2	-1.4	0.8	1.4	-0.8
Relative age voice broke	0.7	1.1	3.7	0.8	0.6	-1.9	1.3	0.0	0.7	-1.5	-1.0	1.0	1.3	0.7	-1.7	1.0	-0.6	-1.4	-0.8	1.1	-0.1	0.6
Taking other prescription medications	0.5	0.8	2.7	0.3	0.7	0.6	-0.3	1.3	0.8	0.9	1.0	1.3	1.6	1.0	0.6	1.0	-0.5	-0.5	1.0	-0.3	-1.0	1.0
Age when periods started (menarche)	0.5	1.3	5.1	0.1	1.3	0.8	-1.1	1.6	1.1	0.8	1.0	1.2	0.4	1.1	0.7	0.9	2.2	0.2	1.4	-1.4	-1.2	1.0
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.4	0.2	-0.4	-0.4	-0.4	0.4	-0.2	-0.2	0.1	-0.1	-0.1	-0.6	-0.3	-0.1	-0.0	0.0	-0.7	-0.4	0.3	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	2.1	-0.1	0.5	1.0	-1.5	0.8	0.9	1.1	1.2	0.6	-1.2	0.3	1.2	0.6	0.2	0.9	1.2	-1.3	-1.1	-0.6
Tinnitus: Yes, but not now, but have in the past	1.5	1.6	4.7	-0.7	0.3	1.9	-2.2	1.1	0.8	1.8	1.4	0.3	0.4	-0.9	1.5	0.1	-1.0	1.7	1.0	-1.4	-1.0	-1.6
Qualifications: CSEs or equivalent	0.2	0.2	1.8	0.3	0.5	0.0	-0.1	0.3	-0.7	-0.0	0.3	-0.1	-1.4	0.5	0.4	-0.0	0.2	-0.5	0.1	0.2	0.1	1.0
Serious illness, injury or assault to yourself	0.2	0.2	1.0	-0.9	-0.7	0.1	-0.6	0.1	0.8	0.0	-0.2	0.4	1.0	-0.5	-0.1	0.3	0.2	-0.0	-0.6	-0.1	-0.2	-0.5
High blood pressure	0.9	2.5	6.6	-1.1	-2.6	0.3	-0.4	-1.8	-2.0	0.2	-0.3	-2.5	-0.5	-2.2	0.2	-2.5	-1.7	1.3	-1.4	0.2	2.0	-1.9
Hayfever, allergic rhinitis or eczema	1.3	2.7	7.0	-0.1	2.5	-0.0	-0.4	2.2	2.0	0.0	0.0	2.5	2.4	1.9	-0.3	2.7	1.0	-1.6	1.5	-0.3	-2.2	1.9
Multivitamins +/- minerals	0.6	0.7	2.6	-0.3	0.6	1.2	0.0	0.3	0.4	1.2	1.5	0.7	-0.3	0.6	1.6	-0.0	1.1	0.8	1.2	-0.8	-0.7	0.0
Stomach or abdominal pain in last month	0.4	0.5	2.2	-1.5	-0.8	-0.1	-0.8	-0.3	-0.9	-0.3	0.1	-1.3	-0.0	-1.0	-0.2	-1.0	0.1	0.1	-0.7	-0.7	1.0	-0.3
Supplements: Glucosamine	0.1	0.2	0.9	0.1	-0.4	0.4	-0.5	-0.2	-0.5	0.4	0.0	0.7	0.3	-0.1	0.3	0.3	-0.9	0.3	0.2	0.6	-0.3	-0.3
Diverticular disease/diverticulitis (self-reported)	1.9	2.3	7.3	-1.5	-1.6	1.9	-1.8	-0.4	0.1	1.8	1.5	-0.7	2.1	-1.2	1.7	-2.0	0.8	2.7	0.6	-0.5	0.5	-1.9
Medication: Atenolol	0.5	0.7	1.7	1.3	-0.5	-0.9	0.9	-0.6	-0.0	-1.1	-1.1	-0.3	1.0	-0.7	-1.1	0.2	-0.9	-1.1	-1.1	0.2	0.5	-0.3
Medication: Levothyroxine sodium	0.8	1.3	2.8	0.2	0.6	1.7	-0.7	1.1	0.7	1.6	1.3	1.5	-0.8	0.7	1.7	1.0	-0.4	0.5	1.7	-1.4	-1.6	0.0
Sitting height	0.4	2.6	12.5	0.5	-1.7	0.2	-2.4	-1.4	-1.5	0.6	1.2	-3.1	3.5	-1.0	1.1	-1.7	0.1	0.9	-0.7	1.6	1.8	-0.3
Chronic bronchitis/emphysema (father)	0.9	1.1	3.0	-1.1	-1.7	0.1	-1.0	-0.3	-1.7	0.3	0.4	-1.3	-0.3	-1.3	0.2	-1.6	-0.7	1.0	-0.7	1.5	1.4	-0.6
High blood pressure (mother)	1.7	2.4	5.0	-0.4	-1.8	-1.4	1.0	-2.0	-1.7	-1.6	-1.6	-1.9	1.9	-2.0	-1.5	-1.5	-0.2	-0.4	-2.0	0.8	2.2	-1.0
Body mass index (BMI)	0.9	3.7	10.3	-0.5	-1.2	3.1	-1.7	-0.1	0.2	2.6	2.0	-0.6	-3.2	-1.6	2.6	-1.1	-0.8	2.8	0.8	-2.8	-0.4	-2.5
Impedance of leg (left)	0.3	1.6	9.7	-1.6	0.5	0.8	-1.5	0.6	0.1	1.3	1.6	0.5	3.1	0.2	1.0	-0.1	0.7	0.8	1.1	2.4	-0.4	0.0
Leg predicted mass (left)	0.2	1.0	4.5	1.1	-1.4	0.6	-0.5	-1.4	-1.0	0.5	0.4	-2.1	-0.6	-0.9	0.8	-1.2	0.3	0.9	-0.6	-0.9	1.1	-0.6
Trunk fat mass	0.7	3.2	10.4	0.4	-0.7	3.2	-2.2	-0.4	0.3	3.0	2.5	-1.1	-1.5	-1.1	3.0	-1.0	-0.2	2.5	1.1	-1.9	-0.4	-1.7
Waist circumference	1.0	3.5	11.3	0.1	-0.5	3.4	-2.5	0.7	0.6	3.1	2.6	-0.2	-2.3	-0.9	3.0	-0.6	-0.7	2.5	1.3	-2.2	-0.9	-1.7
Number of incorrect matches in round	0.8	1.4	3.4	-1.7	-1.7	1.1	-0.3	-0.6	-0.6	0.6	0.9	-0.8	-0.8	-1.8	1.0	-1.5	-1.2	1.8	-0.4	-1.1	0.9	-1.8
Past tobacco smoking	0.5	0.8	2.9	-0.9	-0.7	1.0	0.1	-0.7	-0.2	0.7	1.1	-0.9	-1.2	-0.8	1.1	-1.3	0.4	1.7	0.3	-1.0	0.7	-0.9
Alcohol usually taken with meals	0.8	1.2	2.9	-0.0	-0.8	-1.6	1.0	-1.2	-0.4	-1.5	-1.4	-1.2	0.6	-0.9	-1.6	-0.8	0.5	-0.4	-1.4	1.7	1.3	-0.5
Nervous feelings	0.8	1.5	5.6	1.4	1.4	-0.2	-0.5	0.8	0.8	0.2	0.1	1.4	1.6	1.7	-0.2	1.3	2.4	-0.9	0.5	1.6	-0.9	1.8
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	1.5	0.5	0.5	-0.8	-0.3	1.0	0.8	-0.5	0.3	0.5	0.4	0.5	-0.3	0.9	0.9	-1.0	-0.3	0.1	-0.2	1.2
Hearing difficulty/problems with background noise	0.3	0.5	5.4	0.2	0.3	-0.1	-0.3	0.4	0.9	0.0	-0.4	0.2	2.3	0.1	-0.5	0.1	1.1	-0.0	-0.1	-0.4	-0.3	-0.4
Hair/balding pattern: Pattern 2	1.5	1.9	4.5	0.3	1.7	1.4	-1.5	2.1	1.6	1.1	1.3	1.7	-1.2	0.8	1.1	1.6	-0.2	0.2	1.5	-1.8	-2.0	0.3
Had menopause	1.1	1.3	3.3	0.2	0.7	1.8	-1.4	1.1	0.2	1.5	1.7	0.7	-1.4	0.8	1.7	0.4	0.5	0.5	1.6	-1.3	-1.1	0.6
Had other major operations	1.5	1.9	8.5	-1.9	-0.7	1.7	-2.9	-0.1	-0.6	1.7	1.6	-1.0	0.1	-1.3	1.6	-1.0	-1.0	2.0	0.4	0.6	0.3	-1.5
Forced vital capacity (FVC)	0.7	2.8	6.9	-2.4	-1.8	0.5	-0.1	-2.0	-1.8	0.7	1.0	-2.6	2.5	-1.6	0.9	-2.2	0.4	1.9	-0.5	2.0	1.6	-1.7
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	3.8	0.3	0.5	0.7	-1.3	0.9	0.4	0.5	0.5	0.2	-2.0	0.0	0.6	0.5	0.2	0.6	0.6	-1.7	-0.9	-0.7
Ever unenthusiastic/disinterested for a whole week	2.6	3.1	6.7	0.7	2.6	1.0	-0.5	2.6	2.0	1.4	1.8	2.2	1.6	2.1	1.1	2.1	1.6	-0.5	2.4	-0.6	-2.4	1.6
Qualifications: None of the above	0.8	1.7	6.5	0.1	-1.5	-0.6	2.5	-1.8	-1.3	-1.2	-1.3	-1.2	-1.2	-1.5	-1.1	-1.3	-0.7	0.5	-1.5	-0.6	1.3	-1.2
Financial difficulties in last 2 years	0.3	0.4	2.9	0.0	-0.5	-0.3	0.3	-0.7	-0.0	-0.0	-0.4	-0.2	1.7	-0.4	-0.1	-0.1	-1.5	-0.1	-0.8	1.0	0.1	-0.6
Mouth/teeth dental problems	0.8	1.2	9.7	0.1	0.7	0.9	-1.2	0.9	0.5	0.9	1.5	0.8	0.6	1.0	1.4	0.1	3.1	0.4	1.2	-0.6	-0.6	0.7
Heart attack	0.5	0.6	4.7	0.1	-0.9	-0.3	0.6	-1.0	-1.0	-0.5	-0.6	-0.7	0.4	-1.0	-0.5	-0.4	-2.2	0.0	-0.7	0.1	0.7	-0.8
Allergy	0.8	1.9	5.1	1.4	-1.8	-0.6	0.5	-2.2	-1.6	-0.5	-0.4	-2.3	-1.2	-1.5	-0.3	-1.9	-1.0	0.7	-1.6	1.0	2.0	-1.2
Pain all over the body in last month	0.2	0.3	0.8	-0.4	0.3	-0.2	-0.7	0.9	0.9	-0.0	0.3	0.6	0.5	0.3	-0.3	0.4	-0.5	-0.4	-0.1	0.4	-0.1	0.9
Diabetes (self-reported)	1.3	2.1	7.8	2.8	1.6	0.4	-0.5	1.8	2.2	0.4	0.4	1.5	-0.4	1.7	0.6	1.9	-0.2	-1.5	1.1	-1.3	-1.9	1.4
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	3.3	0.4	1.7	-0.2	0.4	1.3	0.8	-0.2	-0.2	1.7	1.3	1.8	-0.5	1.5	-0.3	-1.3	1.0	0.3	-1.3	1.7
Medication: Ramipril	0.9	1.1	3.0	-0.1	-1.7	0.3	-0.7	-1.3	-1.2	0.3	-0.2	-1.5	-0.1	-1.7	0.5	-1.2	-1.2	1.0	-1.2	0.2	1.1	-1.6
Medication: Simvastatin	0.6	0.9	2.9	0.5	-1.2	-0.4	0.6	-1.1	-0.2	-0.4	-0.9	-0.8	1.6	-1.1	-0.5	-1.0	-1.7	0.3	-1.3	-0.1	1.0	-1.0
Fluid intelligence score	0.7	1.4	3.6	-0.9	1.6	0.2	-1.7	1.5	1.1	0.7	0.5	1.2	1.7	1.0	0.1	1.6	1.9	-0.6	0.8	0.2	-1.3	0.9
Illnesses of siblings	0.2	0.3	2.2	-0.6	0.5	-0.1	0.5	0.2	-0.0	0.2	0.5	0.0	0.2	1.0	0.2	0.3	1.5	-0.4	0.7	0.5	-0.3	1.1
Neuroticism score	0.8	1.6	3.5	1.4	1.7	-0.3	-0.9	1.3	1.2	0.2	0.2	1.7	1.6	1.8	-0.1	1.8	1.7	-1.2	0.6	0.5	-1.4	1.9
Weight	0.5	2.7	7.8	0.3	-1.0	2.8	-2.2	-0.5	-0.2	2.6	2.3	-1.4	-1.3	-1.0	2.7	-1.2	-0.2	2.4	0.8	-1.7	0.0	-1.5
Impedance of arm (right)	0.6	2.9	8.2	1.5	2.0	-2.5	2.2	-0.0	0.6	-2.3	-1.8	0.7	1.5	1.3	-2.2	1.8	0.1	-2.9	-0.8	2.0	-0.3	2.0
Arm fat percentage (right)	0.4	1.6	8.2	0.7	-0.2	1.9	-0.7	-0.2	0.5	1.5	1.1	-0.4	-2.9	-1.2	1.6	-0.2	-0.7	1.4	0.2	-2.0	-0.5	-1.7
Trunk fat-free mass	0.2	1.0	3.9	0.6	-1.4	0.5	-1.3	-1.0	-1.3	0.7	0.7	-2.0	0.6	-0.8	0.9	-1.4	0.1	1.1	-0.3	-0.1	1.2	-0.5
Hip circumference	0.2	0.8	3.3	1.0	-0.6	1.1	-0.2	-0.8	0.3	0.9	0.6	-1.2	-1.8	-0.9	1.0	-0.7	-0.6	0.8	-0.2	-1.4	0.4	-0.9
Time employed in main current job	1.1	1.3	3.2	-1.4	-1.5	0.3	-0.8	-0.5	-0.9	0.1	0.6	-1.8	-1.2	-1.7	0.6	-1.5	-1.4	1.5	-0.5	0.2	1.1	-1.6
Alcohol intake versus 10 years previously	0.6	0.9	4.5	-2.1	-0.5	1.4	0.1	0.0	0.3	1.2	0.6	0.0	-0.0	-0.9	0.8	-0.7	0.5	1.8	0.5	-0.5	-0.2	-1.5
Father’s age at death	0.6	0.8	2.6	1.6	1.0	-0.9	-0.1	1.1	1.1	-1.0	-0.7	0.9	0.7	0.6	-0.9	1.2	-0.3	-1.2	-0.0	-1.1	-0.8	0.6
Worrier / anxious feelings	0.8	1.5	3.5	1.3	1.5	0.8	-1.3	1.7	1.4	0.9	0.6	1.9	0.7	1.5	0.6	1.6	0.8	-0.3	1.3	-0.6	-1.8	1.1
Frequency of tiredness / lethargy in last 2 weeks	1.4	2.3	6.2	0.3	1.5	2.0	-1.8	1.3	1.5	2.1	2.5	1.1	-0.2	1.1	2.3	0.9	1.4	0.8	2.1	-0.7	-1.7	0.4
Falls in the last year	0.5	0.7	3.5	-0.3	-0.4	1.0	-1.9	0.1	-0.2	1.1	1.4	0.0	0.8	-0.5	1.4	-0.2	0.4	0.8	0.6	0.4	-0.2	-0.7
Hair/balding pattern: Pattern 3	0.6	0.9	2.8	-0.9	-1.7	-0.3	-0.9	-0.9	-1.5	-0.1	-0.3	-0.8	0.8	-1.0	-0.1	-1.3	0.6	0.7	-0.8	0.9	1.3	-0.9
Number of live births	0.9	1.3	4.7	1.7	0.6	-1.8	0.4	0.2	1.0	-1.7	-1.5	0.7	0.2	0.5	-1.5	1.2	0.2	-2.2	-1.0	-0.6	-0.1	1.4
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	1.8	-0.8	-0.3	0.2	0.2	-0.9	-0.3	0.0	0.4	-1.3	0.8	-0.6	0.3	-0.7	0.4	0.7	-0.2	0.3	0.4	-0.6
Pulse rate	0.3	0.6	1.6	-0.1	-1.2	0.3	0.3	-1.3	-0.9	0.2	-0.2	-1.0	-0.2	-1.0	0.4	-1.1	-0.8	0.2	-0.8	0.4	0.9	-0.9
Happiness	0.7	0.8	3.3	-0.0	-1.1	-0.4	0.7	-1.2	-1.0	-0.4	-0.4	-1.8	-0.7	-1.1	-0.2	-1.4	0.5	0.4	-1.0	0.6	1.3	-0.7
Noisy workplace	0.1	0.1	0.4	-0.2	0.1	-0.2	0.4	-0.4	-0.3	-0.2	-0.5	-0.2	-0.3	0.3	-0.1	-0.2	-0.6	-0.5	0.0	0.2	0.3	0.4
Qualifications: A levels/AS levels or equivalent	0.4	0.8	3.1	1.5	-0.0	-1.5	0.0	0.1	0.0	-1.1	-0.6	-0.7	1.6	0.0	-0.8	0.0	-0.2	-1.0	-0.8	1.8	0.6	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	2.0	0.4	-0.4	-0.0	0.0	-1.0	0.4	-0.4	-0.7	-0.2	-1.1	-0.8	-0.1	-0.2	-1.4	0.2	-0.5	0.2	0.1	-1.1
Mouth/teeth dental problems: Dentures	0.7	1.2	6.0	-0.4	-0.7	-0.3	1.6	-1.4	-1.5	-0.6	-1.1	-1.1	-0.4	-1.3	-0.8	-0.7	-2.4	0.3	-0.9	0.3	0.9	-1.2
Asthma	0.1	0.2	0.9	-0.4	0.1	-0.1	-0.2	0.8	0.0	-0.1	-0.3	0.4	-0.3	0.7	-0.2	-0.1	0.5	-0.6	0.2	-0.6	-0.0	0.9
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.8	4.6	-0.1	0.8	-1.0	0.6	1.2	1.0	-0.4	0.4	0.9	1.1	1.0	-0.2	1.0	2.2	-0.8	0.2	0.1	-0.5	1.2
Medication: Cholesterol lowering	1.8	2.8	5.6	0.7	-1.4	-2.1	1.2	-1.9	-1.2	-2.1	-2.4	-1.1	2.0	-1.2	-2.2	-0.8	-1.9	-1.1	-2.4	1.7	1.8	-0.5
Depression (self-reported)	0.4	0.5	1.4	0.9	0.5	0.9	-0.1	0.2	-0.3	1.0	1.2	0.4	-0.4	0.8	0.9	0.1	1.0	0.4	1.0	-0.3	-0.6	0.5
Medication: Lansoprazole	0.7	0.8	3.0	-0.1	-1.1	0.9	-0.2	-0.8	-1.7	0.8	0.1	-0.6	0.1	-1.2	0.4	-1.1	-1.4	1.3	-0.2	0.2	0.5	-1.7
Prospective memory result	0.4	0.5	2.5	-0.4	-0.8	0.8	-1.6	0.4	0.3	1.0	0.7	0.0	-0.4	-0.2	0.9	-0.7	-1.3	0.7	0.2	-0.5	0.1	-0.5
Lung cancer (father)	0.8	0.9	6.8	2.6	0.3	-0.6	1.8	-0.2	-0.6	-0.9	-1.1	-0.2	0.5	-0.3	-1.1	0.3	0.9	-1.1	-0.8	-0.0	0.3	0.5
Illnesses of mother	0.6	0.7	2.4	-1.0	0.6	0.2	-1.3	1.6	0.7	0.6	0.4	1.3	-0.9	0.5	0.1	1.0	-1.1	0.4	0.8	0.6	-1.1	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.5	2.0	-0.3	-0.2	1.1	-0.2	-1.0	-0.5	0.9	0.9	-1.4	0.7	-0.4	1.0	-0.7	0.6	1.1	0.3	0.1	0.2	-0.6
Pulse wave Arterial Stiffness index	2.3	2.7	7.9	-0.7	2.1	1.6	-1.0	2.2	2.8	1.2	1.7	2.0	-1.4	1.4	1.0	1.6	0.9	0.5	2.0	-1.8	-2.3	0.6
Impedance of arm (left)	0.5	2.5	7.1	1.7	2.5	-1.7	1.8	0.4	1.5	-1.5	-1.0	1.3	1.0	1.8	-1.5	2.1	0.4	-2.7	-0.1	1.4	-1.0	2.3
Arm fat mass (right)	0.5	2.2	6.2	0.5	-0.8	2.4	-1.3	-0.4	0.2	2.0	1.6	-0.9	-2.5	-1.4	2.1	-0.8	-0.6	2.0	0.3	-2.0	-0.2	-1.9
Trunk predicted mass	0.2	0.9	3.7	0.6	-1.4	0.4	-1.3	-1.0	-1.3	0.6	0.6	-1.9	0.5	-0.7	0.7	-1.3	0.1	0.9	-0.4	-0.1	1.2	-0.5
Standing height	0.2	1.9	13.9	1.4	0.0	-0.1	-1.3	-1.0	-0.8	0.6	1.0	-2.0	3.7	0.9	0.8	-0.5	1.2	-0.1	0.3	2.2	0.8	1.5
Length of working week for main job	0.8	0.9	2.3	-1.1	-0.7	1.0	-0.6	-0.4	-0.3	0.9	0.8	-1.1	-1.5	-0.9	1.1	-0.8	-0.9	1.4	0.1	-1.1	0.4	-1.1
Exposure to tobacco smoke at home	0.4	0.5	2.9	0.8	0.6	0.2	0.5	0.4	0.7	-0.3	0.2	0.8	-1.7	0.0	0.0	0.6	-1.0	-0.1	0.1	-1.6	-0.5	0.1
Breastfed as a baby	0.9	1.1	4.3	-0.7	0.8	1.0	-1.8	1.8	0.3	0.7	0.4	1.0	-2.1	0.4	0.5	0.8	-0.1	0.4	1.1	-1.3	-1.3	-0.1
Tense / ‘highly strung’	0.7	1.2	5.8	0.9	0.7	-0.6	-0.6	1.3	1.0	-0.2	0.4	0.9	1.4	1.6	-0.1	1.4	1.2	-1.6	0.4	0.2	-0.7	2.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	1.7	0.2	1.3	0.3	-0.1	1.0	1.3	0.4	0.9	1.0	-0.3	1.1	0.4	1.2	0.6	-0.3	0.9	-1.2	-1.1	1.3
Hair/balding pattern: Pattern 4	0.4	0.9	7.1	1.6	0.7	-0.5	-0.5	-0.1	1.2	-0.1	0.1	0.7	2.7	0.7	-0.1	0.5	0.6	-1.3	0.2	0.1	-0.2	1.2
Birth weight of first child	2.7	4.8	9.9	0.3	1.9	2.8	-3.1	2.2	1.6	3.2	2.8	1.2	2.5	1.9	2.9	1.3	2.6	1.0	2.8	-1.3	-2.4	0.9
Peak expiratory flow (PEF)	0.4	0.9	5.5	1.1	1.0	-0.8	-0.1	0.2	0.6	-1.0	-0.9	0.7	-2.3	0.8	-0.8	1.2	0.1	-1.1	0.0	-0.8	-0.7	0.9
Pulse wave reflection index	0.8	1.0	3.2	-0.8	1.6	0.6	0.4	1.1	1.8	0.6	1.0	1.1	-0.4	1.2	0.4	0.8	1.2	0.4	1.3	-0.7	-1.2	0.6
Ever highly irritable/argumentative for 2 days	0.6	0.7	4.0	-0.5	-1.0	0.2	-1.4	-0.4	-0.7	0.4	0.7	-0.4	-0.2	-0.9	0.7	-0.7	-2.0	0.6	-0.3	0.7	0.5	-1.1
Loud music exposure frequency	1.2	1.3	3.4	1.5	0.6	-1.8	0.9	-0.6	0.3	-1.8	-1.8	0.2	0.9	0.7	-1.5	0.5	0.2	-1.9	-1.1	1.0	0.5	1.3
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	1.4	0.6	-0.0	-1.0	-0.1	0.4	0.1	-0.9	-0.7	-0.2	1.1	-0.5	-1.0	-0.1	-0.1	-0.5	-0.8	1.2	0.4	-0.3
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	2.3	1.4	-0.4	-0.5	0.1	-0.7	-0.7	-0.5	-1.1	-0.8	-0.3	-0.5	-0.9	0.1	-1.5	-0.8	-0.9	1.4	0.3	-0.2
Blood clot in the leg (DVT)	0.6	0.8	3.3	-0.0	1.0	1.0	-1.1	0.9	1.3	0.6	0.5	1.2	-0.4	0.2	0.8	1.1	-0.2	0.4	0.6	-1.8	-1.4	-0.4
Medication: Paracetamol	0.2	0.4	1.7	-0.0	0.3	0.2	-0.3	1.1	0.5	0.4	0.3	1.3	-0.1	0.1	0.2	0.8	-1.2	-0.1	0.1	0.7	-0.7	0.2
Headache pain in last month	0.4	0.7	5.0	0.6	0.7	0.8	-0.0	0.8	0.4	0.5	0.9	0.6	-0.6	0.7	0.7	0.8	2.2	0.0	0.9	-0.3	-0.9	0.8
Medication for cholesterol, blood pressure or diabetes	1.8	2.9	6.7	-0.1	2.3	1.5	0.1	2.3	2.0	1.3	1.3	2.4	-1.5	1.9	1.0	2.0	1.8	0.2	2.2	-1.8	-2.6	1.0
Glaucoma (self-reported)	0.6	0.7	2.2	1.2	0.5	-0.9	1.5	-0.2	1.1	-0.9	-0.8	0.1	1.2	0.5	-1.0	0.8	0.1	-1.3	-0.3	-0.6	-0.3	0.7
Gout (self-reported)	0.9	1.2	5.2	-0.4	-1.1	-0.1	0.1	-1.2	-0.8	-0.2	-0.5	-1.5	2.3	-1.5	-0.6	-1.4	0.0	1.0	-1.0	1.4	1.1	-1.6
Hypothyroidism/myxoedema (self-reported)	1.5	3.0	7.4	-0.1	1.7	1.9	-1.0	2.2	1.7	2.0	1.8	2.4	-0.3	1.9	1.9	1.8	0.9	0.2	2.7	-1.6	-2.5	1.2
Medication: Amlodipine	0.1	0.2	1.1	1.0	0.3	0.3	0.0	-0.5	0.5	0.1	0.3	-0.2	0.5	0.5	0.4	0.2	-0.3	-0.5	0.2	-0.4	-0.2	0.3
Medication: Ventolin 100micrograms inhaler	0.8	1.1	2.2	0.7	0.9	0.7	-1.2	1.0	1.5	0.9	0.9	1.1	1.5	1.1	1.0	0.6	1.3	-0.5	0.9	-1.3	-1.0	0.9
Birth weight	1.1	2.5	6.8	-1.2	-1.8	1.9	-1.6	-1.3	-1.3	2.1	1.7	-0.8	0.9	-1.5	2.3	-1.0	-0.8	2.6	0.5	1.7	0.4	-2.1
Chronic bronchitis/emphysema (mother)	0.2	0.3	2.0	0.6	0.0	0.7	-1.4	0.3	0.5	0.5	0.5	0.3	0.4	-0.3	0.5	0.1	-0.3	0.2	0.0	-0.8	-0.3	-0.2
High blood pressure (siblings)	0.6	0.9	2.4	-0.8	-0.9	1.4	-1.3	0.1	-0.2	0.9	0.9	-0.7	-0.2	-1.1	1.2	-1.3	-0.3	1.5	0.1	-0.9	0.4	-1.2
Forced vital capacity (FVC), Best measure	0.6	2.1	5.3	-1.5	-1.3	1.2	-0.2	-1.7	-1.5	1.2	1.4	-2.2	2.3	-1.1	1.4	-1.7	0.4	1.8	0.2	1.7	1.0	-1.3
Body fat percentage	0.9	3.5	11.5	-0.1	-0.5	3.4	-2.2	-0.1	0.5	3.1	2.6	-0.5	-1.9	-1.3	3.0	-0.8	-0.4	2.7	1.2	-1.9	-0.7	-2.1
Leg fat percentage (right)	1.3	4.8	14.4	-1.1	-0.9	3.8	-3.0	0.4	0.3	3.5	3.2	-0.1	-1.5	-1.5	3.4	-1.1	-0.2	3.6	1.5	-1.9	-0.7	-2.6
Arm fat-free mass (right)	0.5	2.4	5.1	0.0	-1.8	2.1	-2.3	-1.0	-1.2	2.1	1.8	-2.0	-0.0	-1.0	2.2	-1.8	0.5	2.3	0.4	-0.9	0.9	-1.2
Exposure to tobacco smoke outside home	0.9	1.2	3.2	-1.8	-1.2	0.4	0.1	-1.3	-1.3	0.2	0.5	-1.1	-1.0	-1.6	0.5	-1.5	0.4	1.8	-0.3	0.7	1.1	-1.6
Comparative body size at age 10	1.3	3.5	11.6	-2.4	-2.5	1.8	-0.7	-1.6	-1.2	1.4	1.1	-2.3	-1.1	-2.0	1.5	-3.1	-0.5	3.4	0.1	-0.1	1.5	-2.8
Number of full brothers	2.4	3.1	7.7	-0.0	1.7	2.2	-1.6	2.2	1.5	2.4	2.8	1.8	-1.2	1.8	2.3	1.1	0.6	0.7	2.4	-1.2	-2.2	0.8
Worry too long after embarrassment	0.4	0.7	5.2	0.7	0.7	0.2	-1.0	1.2	0.7	0.6	0.6	0.9	2.3	0.8	0.5	0.8	0.3	-0.1	0.7	0.4	-1.0	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	3.8	-0.1	0.7	0.6	0.3	0.3	0.3	0.4	1.3	0.5	0.2	1.0	0.9	0.5	1.9	-0.1	1.0	-0.5	-0.7	1.0
Wheeze or whistling in the chest in last year	0.5	0.9	3.3	-1.8	-1.0	1.3	-0.4	-0.4	-0.3	1.0	0.7	-0.4	-0.9	-0.9	1.0	-1.3	-0.6	1.3	-0.1	-0.9	0.5	-1.0
Number of children fathered	0.9	1.0	5.0	0.6	-1.2	-0.7	0.6	-1.4	-0.4	-0.8	-0.9	-1.2	0.3	-0.8	-0.7	-0.9	-2.2	-0.2	-1.3	0.9	1.3	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	3.0	1.7	0.7	0.1	-0.3	0.4	-0.0	0.1	0.2	0.3	0.6	1.0	0.4	0.5	0.8	-0.5	0.7	0.1	-0.3	1.1
Age at first live birth	0.2	0.4	1.3	0.5	-0.1	-0.9	-0.0	0.0	-1.0	-0.8	-0.8	-0.6	-0.3	0.1	-0.6	-0.2	-0.6	-1.1	-0.6	0.3	0.6	0.6
Pulse wave peak to peak time	2.3	2.7	7.7	0.7	-2.0	-1.5	0.8	-2.2	-2.8	-1.1	-1.5	-2.1	2.1	-1.4	-0.8	-1.7	-0.6	-0.4	-1.9	2.0	2.3	-0.5
Health satisfaction	0.9	1.2	5.7	2.4	0.9	-1.1	1.1	-0.0	0.5	-0.9	-0.8	0.6	1.4	1.0	-1.0	0.6	0.7	-1.8	-0.3	0.7	0.1	1.6
Shortness of breath walking on level ground	1.2	1.4	4.4	2.1	1.8	-0.5	0.9	0.8	0.8	-0.4	-0.1	1.2	-0.7	1.4	-0.3	1.7	0.9	-1.9	0.4	-0.4	-0.9	2.0
Qualifications: College or University degree	0.4	1.1	3.2	0.3	1.5	-0.4	-1.2	1.0	1.2	0.2	0.6	0.5	-0.1	1.8	0.6	1.2	1.8	-1.0	1.1	0.7	-0.9	1.8
Eye problems/disorders: None of the above	0.4	0.4	2.3	-0.6	0.3	0.0	-0.4	0.7	-0.3	0.0	-0.1	0.9	-1.5	1.1	0.1	0.5	0.9	-0.5	0.2	0.0	-0.4	1.2
Mouth/teeth dental problems: Loose teeth	0.2	0.3	2.9	-0.4	0.3	-0.2	-0.4	0.5	0.3	0.2	0.3	0.5	-0.1	-0.1	-0.0	0.5	-1.7	-0.6	0.0	-0.4	-0.2	0.2
Emphysema/chronic bronchitis	0.2	0.2	0.9	-0.3	-0.5	0.5	0.7	0.0	-0.3	0.2	0.4	-0.3	-0.9	-0.7	0.3	-0.5	0.2	0.5	-0.2	-0.7	0.2	-0.7
Medication for pain relief, constipation, heartburn	1.1	1.8	5.4	-1.8	-1.6	0.5	-0.1	-1.7	-2.3	0.0	-0.4	-2.1	-0.9	-1.6	0.2	-2.1	0.3	1.7	-0.4	-0.0	1.4	-1.9
Neck or shoulder pain in last month	0.9	1.3	4.1	0.5	0.9	0.7	-1.4	1.1	0.4	1.3	0.9	2.0	1.3	1.2	0.9	1.6	0.6	-0.4	1.3	1.3	-1.4	1.0
Medication: Blood pressure	0.7	1.2	3.4	0.4	-1.6	-0.8	-0.3	-1.4	-1.5	-0.8	-0.8	-1.9	0.4	-1.2	-0.5	-1.3	-0.9	-0.3	-1.4	0.4	1.8	-0.3
Angina (self-reported)	0.5	0.7	2.0	0.9	0.3	-1.2	0.4	0.5	0.4	-0.8	-0.5	0.3	1.4	0.5	-1.0	0.7	-1.3	-1.4	-0.4	0.9	-0.0	0.9
Migraine (self-reported)	0.3	0.3	1.5	1.2	0.4	0.0	-0.9	0.9	0.7	-0.2	-0.1	1.0	-0.3	0.1	-0.1	0.9	-0.4	-0.1	0.1	-0.1	-0.6	0.1
Medication: Ibuprofen	0.6	0.7	2.3	0.6	0.3	-1.2	0.3	0.5	0.8	-0.5	0.1	0.7	1.5	0.8	-0.2	0.6	1.4	-1.1	-0.3	1.0	-0.1	1.2
Medication: Allopurinol	1.1	1.5	3.9	-1.1	-1.2	-0.2	1.0	-1.5	-0.7	-0.2	-0.6	-1.7	2.0	-1.3	-0.6	-1.7	-0.7	1.1	-1.2	1.7	1.4	-1.4
Medication: Omeprazole	3.2	3.8	8.4	0.2	2.1	1.8	-1.7	2.9	1.9	2.0	2.5	2.5	0.0	2.1	1.7	2.3	0.6	-0.2	2.8	-1.1	-2.6	1.9
Medication: Seretide 50 evohaler	1.1	1.3	6.6	-0.3	-0.6	1.4	-2.6	1.1	0.3	1.3	1.8	0.2	-1.0	-0.3	1.8	-0.4	0.3	1.3	1.0	-0.8	-0.4	-0.7
Mean time to correctly identify matches	1.0	1.8	4.2	-0.5	1.3	1.6	-0.9	1.8	2.1	1.6	1.9	1.2	-0.3	1.2	1.7	1.0	0.3	0.6	1.8	-1.6	-1.8	0.5
Heart disease (mother)	0.6	0.7	4.6	1.3	0.9	0.7	-0.0	0.3	1.6	0.2	0.1	0.7	-0.4	0.5	0.5	0.6	-0.3	-0.4	0.4	-2.2	-1.0	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.9	2.3	5.5	-1.5	-1.5	-0.8	1.2	-1.9	-1.2	-1.3	-1.5	-1.5	-2.1	-2.3	-1.0	-1.5	-1.1	0.5	-2.1	0.5	1.7	-2.1
Whole body fat mass	0.9	3.6	10.8	-0.2	-1.0	3.3	-2.3	-0.4	0.1	3.0	2.5	-1.1	-1.8	-1.6	3.0	-1.2	-0.6	2.9	0.9	-1.9	-0.2	-2.2
Leg fat mass (right)	1.0	4.0	11.3	-0.5	-1.3	3.4	-2.8	-0.2	-0.2	3.1	2.7	-0.9	-1.7	-1.6	3.1	-1.4	-0.4	3.2	1.1	-1.8	-0.2	-2.4
Arm predicted mass (right)	0.4	2.2	5.1	-0.0	-1.8	2.0	-2.3	-1.1	-1.2	2.0	1.6	-2.0	0.3	-1.1	2.0	-1.9	0.5	2.2	0.3	-0.7	1.0	-1.2
Pulse rate, automated reading	0.7	2.2	6.4	-2.5	-1.6	1.9	-2.2	0.2	0.0	1.9	1.4	-0.0	1.4	-1.4	1.7	-1.3	-0.1	2.5	0.4	0.2	0.2	-2.1
Alcohol intake frequency.	0.8	1.9	5.1	-1.3	0.6	2.2	-0.8	1.3	0.9	2.1	2.2	0.8	-0.8	-0.2	2.0	0.5	0.9	1.6	1.8	-1.7	-1.3	-0.6
Comparative height size at age 10	0.2	0.8	3.2	1.3	0.4	0.3	-1.1	-0.5	-0.0	0.7	1.2	-1.0	1.8	1.0	1.0	0.1	0.3	-0.2	0.6	1.3	0.1	1.5
Number of full sisters	0.5	0.6	3.4	1.5	0.5	0.4	-0.3	0.6	0.2	0.0	-0.6	0.9	-1.8	0.6	-0.0	1.0	0.4	-0.7	0.2	-1.0	-0.9	0.4
Suffer from ‘nerves’	2.9	4.5	15.0	1.8	3.1	-0.5	0.4	2.3	1.6	-0.0	0.7	2.5	0.9	3.6	-0.1	2.9	2.9	-2.4	1.6	-0.1	-2.2	3.9
Overall health rating	1.4	3.1	6.3	0.0	1.7	1.7	-2.1	2.5	2.5	2.2	2.1	2.3	1.2	1.2	1.4	1.6	1.5	0.2	1.9	-1.3	-2.0	0.9
Chest pain or discomfort	1.6	2.3	4.0	0.4	1.8	0.7	-1.3	1.8	1.9	1.3	1.9	1.8	1.8	2.0	1.4	1.7	0.8	-0.7	2.0	-0.1	-1.8	1.8
Had major operations	0.5	0.6	1.5	-0.4	1.2	0.3	-0.9	1.1	0.6	0.5	0.6	0.7	-0.2	1.0	0.4	1.1	-0.5	-0.6	0.9	-0.8	-1.2	0.6
Age at last live birth	1.2	1.7	5.5	1.0	-0.4	-2.1	1.6	-0.5	-1.0	-2.1	-2.4	-0.7	-0.6	-0.1	-1.9	0.2	-0.7	-1.9	-1.6	0.3	0.9	0.6
Family relationship satisfaction	0.1	0.1	0.9	-0.0	0.3	-0.6	-0.2	0.3	0.9	-0.4	-0.1	-0.1	0.0	0.1	-0.2	0.0	0.1	-0.5	-0.4	0.4	0.0	0.1
Leg pain on walking	0.4	0.5	1.3	0.2	1.1	-0.0	0.5	0.5	1.1	-0.0	0.3	0.8	-0.7	1.0	0.3	0.6	1.2	-0.9	0.5	-0.9	-0.6	1.0
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	3.9	-0.3	-0.7	0.1	0.2	-0.2	-1.0	0.3	0.2	0.2	-0.6	0.4	0.3	-0.2	0.5	0.1	0.3	2.0	0.4	0.6
Commuting to job workplace: Car/motor vehicle	1.5	1.7	3.6	0.0	-1.3	-1.6	1.8	-1.7	-1.2	-1.4	-1.5	-1.9	0.3	-0.8	-1.4	-1.4	-0.4	-0.3	-1.8	1.1	1.9	-0.3
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	0.8	-0.1	0.6	-0.4	0.1	0.6	0.3	-0.2	0.2	0.1	-0.9	0.4	-0.4	0.3	0.3	-0.4	0.1	0.3	0.0	0.9
Medication: Aspirin	0.4	0.5	2.5	1.4	0.2	-0.4	1.3	-0.2	1.0	-0.4	-0.3	0.0	-0.2	0.2	-0.3	0.7	-1.6	-0.9	-0.6	-0.3	-0.2	0.4
Supplements: Vitamin C	0.9	1.1	3.9	-0.0	1.0	-0.0	-1.2	1.8	1.5	0.1	0.8	0.8	-1.1	0.4	0.2	1.3	-1.2	-0.8	0.7	-2.0	-1.0	0.8
Knee pain experienced in last month	0.2	0.3	1.7	0.4	-0.2	0.6	-0.3	-0.3	-0.7	0.5	0.4	0.0	0.3	-0.7	0.5	-0.4	0.7	0.5	0.1	1.3	0.4	-0.3
Hypertension (Self-reported)	1.3	3.5	8.9	-1.4	-3.0	0.3	-0.7	-2.0	-2.4	0.1	-0.3	-3.0	-0.5	-2.7	0.2	-2.9	-2.0	1.6	-1.6	0.3	2.4	-2.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	0.8	-0.4	-0.2	0.6	-0.5	0.3	-0.7	0.6	0.7	-0.1	-0.9	-0.6	0.6	-0.1	-0.6	0.5	0.2	-0.3	-0.1	-0.7
Illnesses of father: Heart disease	0.4	0.6	1.6	-0.5	-0.6	-0.8	0.1	-1.0	0.1	-0.9	-0.9	-1.0	-0.9	-0.6	-0.9	-0.7	-0.6	-0.5	-1.3	-0.3	0.8	-0.5
Illnesses of siblings: Diabetes	0.1	0.2	0.6	0.6	0.3	-0.8	0.1	-0.2	0.3	-0.6	-0.6	0.5	-0.3	0.1	-0.8	0.2	0.1	-0.5	-0.2	-0.1	0.0	0.1
Smoking status: Previous	0.7	1.0	2.9	1.0	-0.3	-1.4	-0.2	-0.5	-0.6	-1.2	-1.5	-0.1	1.7	-0.0	-1.4	0.1	-0.5	-1.4	-1.1	1.6	0.6	0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	3.4	0.8	-0.1	-0.2	0.3	-1.0	-0.5	-0.0	-0.1	-1.4	1.6	-0.1	0.1	-0.5	0.0	-0.4	-0.4	1.9	0.8	0.3
Whole body fat-free mass	0.2	1.1	4.8	0.6	-1.5	0.8	-1.2	-1.2	-1.2	0.8	0.7	-2.2	0.1	-0.9	1.0	-1.5	0.2	1.2	-0.3	-0.4	1.2	-0.7
Leg fat-free mass (right)	0.2	0.9	4.5	1.0	-1.3	0.7	-0.4	-1.4	-1.0	0.6	0.3	-2.1	-0.8	-0.9	0.9	-1.1	0.1	0.8	-0.5	-0.9	1.0	-0.7
Arm fat percentage (left)	0.6	2.3	9.8	0.7	-0.0	2.5	-1.1	0.0	0.9	2.1	1.7	-0.2	-3.1	-1.0	2.1	-0.1	-0.6	1.7	0.7	-2.4	-0.9	-1.6
Average weekly red wine intake	0.3	0.5	3.0	-0.9	-0.5	0.2	-0.5	-0.7	-0.3	0.7	0.2	-1.0	0.5	-0.2	0.2	-0.8	-0.3	0.7	0.0	1.7	0.6	-0.4
Handedness (chirality/laterality): Left-handed	0.5	0.6	3.0	0.9	0.4	-1.1	0.5	0.1	-0.0	-0.9	-0.5	-0.3	-0.3	0.6	-0.8	0.5	0.0	-1.7	-0.4	0.9	0.4	1.7
Mood swings	0.3	0.5	3.9	0.3	0.5	-0.5	-0.2	0.5	0.9	-0.4	-0.4	0.7	0.4	0.7	-0.6	0.4	2.0	-0.7	-0.0	0.5	-0.1	1.2
Loneliness, isolation	1.1	1.5	5.2	0.7	1.3	0.9	-1.1	1.3	1.2	1.1	1.7	0.9	1.4	1.4	1.3	0.9	2.3	-0.0	1.4	-0.3	-1.3	1.2
Long-standing illness, disability or infirmity	1.3	2.0	7.2	0.5	1.4	1.0	-1.1	1.8	1.3	1.4	1.4	1.8	2.7	1.6	0.8	1.1	1.4	-0.4	1.7	-0.6	-1.5	1.4
Ever had bowel cancer screening	0.4	0.5	1.9	-0.2	-0.8	0.9	-1.4	0.3	0.1	0.8	0.6	-0.8	-0.2	-0.5	0.8	-0.8	0.8	1.0	-0.0	-0.4	0.2	-0.4
Diabetes diagnosed by doctor	0.5	0.8	4.3	2.1	0.7	0.2	-0.7	1.1	1.5	0.3	0.2	0.8	-0.4	0.8	0.5	1.0	-0.2	-1.0	0.5	-0.5	-1.0	0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.3	0.8	0.8	0.3	-0.6	0.7	0.0	-0.0	-0.7	-0.9	-0.1	0.4	-0.4	-0.8	0.3	0.2	-0.7	-0.6	0.4	0.1	-0.0
Friendships satisfaction	0.5	0.7	1.6	0.9	-0.0	-1.1	0.6	-0.2	0.8	-1.3	-1.1	-0.6	-1.2	-0.0	-1.0	-0.1	-0.7	-1.1	-1.1	-0.4	0.5	0.5
Qualifications: nursing, teaching	0.3	0.5	2.6	-0.8	-0.5	0.7	-1.6	0.4	0.4	0.7	0.5	-0.3	-0.1	-0.6	0.7	-0.5	-0.7	1.0	0.4	-0.2	0.1	-0.9
Commuting to job workplace: Walk	2.5	2.7	5.7	-0.4	1.2	2.4	-2.3	1.4	2.2	2.2	2.2	1.1	-1.0	0.7	2.3	0.6	1.4	1.3	2.1	-1.7	-1.8	-0.2
Eye problems/disorders: Cataract	1.1	1.3	3.0	-0.6	0.0	1.7	-1.7	0.5	1.2	1.5	1.4	-0.5	-0.3	-0.4	1.6	-0.5	-0.9	1.7	1.0	-1.7	-0.6	-1.2
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	2.2	-0.1	-1.3	-1.4	1.4	-0.6	0.0	-1.4	-1.2	-0.8	-0.9	-0.6	-1.1	-0.4	-1.0	-0.5	-1.5	0.2	1.0	-0.2
Medication for cholesterol	0.3	0.5	2.2	-1.0	-0.2	-1.1	-0.1	0.4	-1.1	-0.9	-0.9	-0.0	0.7	-0.1	-1.1	-0.2	-0.5	-0.2	-0.4	1.5	0.4	-0.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	2.8	1.7	1.0	-0.3	0.1	0.5	1.1	-0.3	-0.5	1.1	-0.9	0.6	-0.3	1.4	-1.1	-1.1	-0.0	-0.1	-0.8	0.7
Back pain experienced in last month	0.9	1.3	4.2	-1.2	-0.6	1.5	-1.3	0.4	-0.4	1.5	1.2	0.4	0.0	-1.3	1.2	-0.5	-1.8	2.0	0.7	0.2	-0.3	-1.9
Mineral and other dietary supplements	0.2	0.3	0.8	0.1	0.2	-0.6	-0.4	0.1	0.4	-0.5	-0.5	-0.9	0.0	0.1	-0.6	-0.4	0.8	-0.6	-0.4	-0.4	0.6	0.7
Breast cancer (self-reported)	0.6	0.8	2.3	-0.5	0.3	1.5	-0.9	0.5	0.3	1.5	1.5	0.2	0.5	0.2	1.5	-0.2	0.8	0.9	1.2	-0.4	-0.7	-0.3
Asthma (self-reported)	0.1	0.2	1.0	-0.6	0.2	0.0	-0.3	0.9	0.2	-0.0	-0.1	0.4	-0.5	0.7	0.0	0.0	0.6	-0.6	0.4	-0.7	-0.2	1.0
Osteoporosis (self-reported)	0.4	0.5	2.3	0.5	0.6	0.5	0.3	1.0	0.6	0.2	-0.0	1.5	-1.0	0.2	0.1	1.1	0.5	0.1	0.5	-1.2	-1.1	-0.0
Osteoarthritis (self-reported)	0.5	0.7	3.3	0.1	-0.8	0.3	0.2	-1.3	-0.2	0.2	-0.4	-0.2	1.4	-1.2	-0.0	-0.6	-1.8	0.3	-0.7	0.9	0.7	-1.2
Medication: Aspirin	0.5	0.7	2.9	1.6	0.5	-0.5	1.0	0.1	1.1	-0.6	-0.5	0.4	-0.1	0.6	-0.5	1.0	-1.7	-1.2	-0.5	-0.6	-0.5	0.7
Medication: Gliclazide	0.7	0.7	1.4	1.1	0.9	0.7	-0.5	0.9	1.0	0.9	0.9	0.6	0.6	1.1	0.9	0.7	1.0	-0.4	1.2	-0.5	-0.9	1.0
Illnesses of father: None of the above (group 1)	1.9	2.4	5.3	1.1	1.6	2.0	-0.3	1.4	0.4	1.7	1.8	1.4	-2.1	1.4	2.0	1.4	1.3	0.6	2.3	-1.7	-1.8	1.1
Smoking status: Current	0.3	0.5	1.0	-0.5	0.9	0.9	0.8	0.8	0.2	0.9	1.0	0.8	-0.0	0.4	0.9	0.7	0.0	0.2	1.0	-0.1	-1.0	-0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.7	2.9	-0.6	-1.1	-0.2	0.6	-1.3	-0.6	-0.4	-0.3	-1.7	1.5	-0.8	-0.3	-1.1	0.2	0.5	-0.8	0.5	1.1	-0.6
Whole body water mass	0.2	1.2	4.9	0.6	-1.6	0.8	-1.2	-1.3	-1.3	0.8	0.6	-2.2	0.1	-0.9	1.0	-1.5	0.2	1.2	-0.4	-0.4	1.2	-0.7
Leg predicted mass (right)	0.2	1.0	4.5	0.9	-1.3	0.8	-0.4	-1.4	-0.9	0.6	0.4	-2.1	-0.8	-0.8	0.9	-1.1	0.2	0.9	-0.5	-1.0	1.0	-0.7
Arm fat mass (left)	0.7	2.8	7.9	0.3	-0.8	2.8	-1.7	-0.3	0.2	2.4	1.9	-0.9	-2.7	-1.4	2.5	-0.8	-0.7	2.3	0.6	-2.2	-0.3	-2.0
Number of self-reported non-cancer illnesses	0.9	1.6	5.1	-1.9	-0.3	1.8	-2.3	1.0	0.2	1.9	2.0	0.1	1.3	-0.7	1.6	-0.6	-0.8	1.6	1.0	0.1	-0.3	-0.8
Average weekly champagne plus white wine intake	3.1	4.3	9.4	0.1	-1.4	-3.0	2.5	-2.5	-1.7	-3.1	-3.0	-1.9	0.5	-1.5	-2.9	-1.3	-0.9	-1.1	-2.9	1.7	2.5	-0.9
Miserableness	1.0	1.8	3.8	1.0	-0.7	-1.8	1.2	-1.6	-1.7	-1.7	-1.8	-1.0	0.2	-1.1	-1.9	-0.4	-0.3	-0.9	-2.0	1.9	1.4	-0.3
Guilty feelings	0.7	1.0	3.1	1.2	1.5	-0.2	0.4	0.5	0.9	-0.3	-0.5	1.4	-0.4	1.4	-0.3	1.8	0.6	-1.4	0.6	-0.1	-1.2	1.7
Wears glasses or contact lenses	0.6	0.7	2.2	-0.9	-0.0	1.0	-1.3	0.4	0.3	1.1	1.5	0.3	-0.0	-0.6	1.2	0.2	0.4	1.4	0.6	-0.2	-0.7	-1.3
Ever taken oral contraceptive pill	0.9	1.0	4.8	-2.2	-0.7	-1.1	1.3	-0.6	0.0	-0.6	-0.2	-0.3	1.2	-0.5	-0.6	-0.5	-1.1	0.1	-0.9	2.0	0.9	-0.3
Hearing aid user	0.9	1.1	6.0	-0.5	-0.7	-0.9	1.4	-0.6	-0.0	-0.9	-1.4	-0.6	-0.5	-1.1	-1.3	-0.3	-2.4	-0.2	-1.6	-0.4	0.6	-1.1
Mother’s age at death	0.2	0.3	1.2	-0.4	-0.3	-0.6	-0.5	-0.3	-0.2	-0.6	-0.5	-0.3	0.6	-0.4	-0.3	0.0	-1.1	-0.1	-0.5	1.0	0.2	-0.4
Financial situation satisfaction	0.7	0.9	3.3	-0.9	-0.8	-0.3	-0.3	-0.8	-0.5	-0.4	-0.2	-1.6	-1.8	-1.0	-0.2	-1.5	-1.3	0.6	-1.1	0.3	1.2	-0.9
Tinnitus: Yes, now most or all of the time	2.0	2.3	9.4	1.8	1.4	-2.2	1.1	-0.0	1.2	-1.6	-1.4	1.2	1.1	1.4	-1.8	1.8	0.2	-3.1	-0.6	0.8	-0.3	2.2
Commuting to job workplace: Public transport	1.0	1.2	5.2	0.1	1.2	0.4	-1.3	2.3	1.2	0.6	0.9	1.5	0.2	0.8	0.4	1.6	0.0	-0.8	1.0	-0.8	-1.4	1.0
Eye problems/disorders: Glaucoma	0.5	0.5	3.0	0.5	0.7	-0.8	1.7	-0.3	0.6	-0.8	-0.4	0.4	0.8	0.5	-0.8	0.9	0.1	-1.1	-0.0	-0.2	-0.3	0.8
Medication: Blood pressure	0.5	1.0	2.4	-0.2	-1.2	0.8	0.2	-1.2	-0.6	0.3	0.2	-1.5	-0.9	-1.5	0.5	-1.4	-1.3	1.0	-0.7	-0.8	0.9	-1.5
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.5	-0.5	-0.3	-0.2	0.3	-0.5	-0.3	-0.1	-0.0	0.4	0.5	-0.3	0.0	0.1	0.2	0.2	0.0	0.7	-0.1	-0.5
Supplements: Fish oil (including cod liver oil)	0.8	1.1	3.4	-1.7	-0.4	1.5	-0.5	-0.0	-0.6	1.5	1.4	0.7	-0.5	-0.5	1.6	-0.1	-0.4	1.9	0.8	-0.5	-0.6	-1.3
High cholesterol (Self-reported)	1.1	2.0	3.7	-0.8	-1.9	-0.5	0.1	-1.8	-1.8	-0.2	-0.8	-1.4	1.6	-1.8	-0.5	-1.9	-1.6	0.6	-1.5	1.6	1.9	-1.6
Medication: Bendroflumethiazide	1.0	1.5	3.1	0.3	-1.3	-1.2	0.8	-1.7	-0.9	-1.2	-1.1	-1.8	-1.6	-1.0	-0.8	-1.1	-1.4	-0.7	-1.7	-0.6	1.7	-0.2
Medication: Paracetamol	0.2	0.4	3.0	0.8	-0.2	-0.4	0.3	0.1	0.2	-0.3	-0.5	0.7	-0.1	-0.0	-0.4	0.4	-1.7	-0.6	-0.6	1.1	-0.0	0.2
Medication: Lisinopril	0.4	0.5	2.4	-0.4	-0.9	-0.7	-0.5	-0.6	-0.1	-0.6	-0.3	-1.0	1.0	-0.4	-0.5	-0.9	-1.5	0.0	-0.9	0.6	1.0	-0.2
Medication: Atorvastatin	0.2	0.3	1.4	-0.2	0.2	0.0	-0.6	0.3	0.6	0.4	0.6	0.1	1.0	0.6	0.3	0.1	0.8	-0.3	0.4	1.2	0.0	0.7
Illnesses of father: High blood pressure	0.9	1.2	4.6	-1.7	-1.2	-0.5	-1.2	-0.9	-0.7	-0.2	-0.2	-1.0	2.1	-1.0	-0.1	-1.5	0.2	0.6	-1.0	1.2	1.3	-1.1
Alcohol drinker status: Never	1.3	1.5	5.1	-0.4	0.0	2.2	0.2	0.7	0.9	1.8	1.9	0.7	-1.3	0.2	2.0	-0.2	0.3	1.5	1.6	-1.5	-1.1	-0.5
Ever smoked	1.0	1.8	6.5	1.2	1.9	-0.3	-0.4	1.8	0.9	0.0	-0.5	2.1	0.9	1.6	-0.5	2.5	-0.3	-1.8	0.8	0.9	-2.0	1.3
Basal metabolic rate	0.3	1.4	4.5	0.6	-1.5	1.3	-1.4	-1.2	-1.0	1.3	1.1	-2.1	-0.3	-1.1	1.5	-1.5	0.1	1.5	-0.2	-0.7	1.0	-1.0
Leg fat percentage (left)	1.5	5.5	17.2	-1.3	-1.0	4.2	-2.9	0.2	0.3	3.8	3.2	-0.3	-1.6	-1.7	3.7	-1.2	-0.3	3.9	1.6	-2.0	-0.8	-2.9
Arm fat-free mass (left)	0.3	1.8	4.9	0.2	-1.8	1.4	-1.7	-1.2	-1.4	1.4	1.1	-2.2	0.2	-1.2	1.5	-1.9	0.2	1.9	-0.2	-0.5	1.2	-1.2
Number of operations (self-reported)	1.8	2.7	10.2	-2.2	0.4	2.2	-3.2	1.4	0.7	2.7	2.4	0.6	1.1	0.3	2.1	0.2	0.6	1.9	1.9	0.1	-1.3	-0.5
Average weekly beer plus cider intake	0.4	0.6	2.2	0.5	-0.5	-0.7	1.5	-0.9	-1.1	-0.6	-1.1	-0.2	-0.1	0.4	-0.7	-0.5	-0.7	-0.6	-0.7	1.1	0.5	0.4
Irritability	1.6	2.8	5.8	1.4	2.2	0.5	-1.3	2.1	2.4	0.7	0.9	2.4	0.1	2.3	0.6	2.3	1.4	-1.0	1.7	-1.2	-2.2	2.1
Risk taking	1.4	2.0	5.3	0.5	1.8	-0.9	0.3	2.0	1.2	-0.6	-0.3	1.7	-1.5	1.8	-0.8	2.3	0.5	-2.0	0.5	-1.1	-1.4	2.3
Ever had prostate specific antigen (PSA) test	0.3	0.3	2.1	-0.0	0.1	-0.9	0.6	-0.4	0.7	-0.7	-0.5	-0.5	1.4	0.2	-0.6	-0.3	0.1	-0.5	-0.5	0.3	0.6	0.3
Fractured/broken bones in last 5 years	0.4	0.6	2.0	0.2	0.9	-0.6	0.3	0.9	0.8	-0.5	0.2	0.7	-0.3	1.1	-0.4	1.1	0.9	-1.2	0.1	-0.3	-0.6	1.4
Age started oral contraceptive pill	0.1	0.1	0.6	0.1	-0.7	0.3	-0.2	-0.4	-0.3	0.1	0.0	0.2	-0.8	-0.3	0.3	0.0	-0.2	0.4	-0.2	-0.0	-0.2	-0.5
Diastolic blood pressure, automated reading	0.3	1.1	3.9	-2.0	-1.7	0.2	-0.4	-0.3	-1.0	0.2	-0.2	-0.5	0.7	-1.6	-0.2	-1.4	-0.6	1.2	-0.8	-0.3	0.9	-1.9
Ever depressed for a whole week	0.5	0.6	1.3	0.0	0.8	0.3	-0.6	1.1	0.9	0.7	0.9	1.0	1.1	0.7	0.8	0.9	0.7	0.2	0.9	0.2	-1.1	0.2
Unable to work because of sickness or disability	0.4	0.5	3.4	0.1	0.2	0.2	-0.7	1.0	-0.3	0.5	0.9	0.9	1.8	0.5	0.5	0.5	0.3	-0.1	0.5	0.8	-0.5	0.6
Commuting to job workplace: Cycle	2.2	2.7	7.7	-1.1	0.9	2.5	-2.2	1.4	0.8	2.8	2.2	1.2	-0.5	1.3	2.4	0.6	0.7	1.7	2.5	-0.2	-1.9	-0.2
Myopia	0.2	0.3	1.7	-0.1	-0.2	0.7	-0.2	0.2	0.5	0.7	0.8	-0.3	0.2	-0.2	0.8	-0.4	1.3	0.8	0.2	-0.4	-0.2	-0.6
Vascular/heart problems diagnosed by doctor	1.0	2.7	7.1	0.7	2.6	-0.0	-0.0	2.0	2.0	0.1	0.6	2.7	0.1	2.4	0.1	2.4	2.3	-1.1	1.6	-0.6	-2.2	1.9
Cholesterol lowering medication	0.4	0.6	2.5	0.1	-0.4	1.5	-0.6	-0.2	0.5	1.6	0.9	-0.4	0.5	-0.3	1.4	-0.8	0.0	1.0	0.5	-0.9	-0.1	-0.8
Medication: Omeprazole (e.g. Zanprol)	3.9	4.7	10.0	0.1	2.1	2.6	-2.5	3.0	1.8	2.7	3.2	2.5	-0.2	1.8	2.5	2.2	0.2	0.4	3.2	-1.5	-2.9	1.3
Pain experienced in last month	0.4	0.6	1.5	0.1	-0.2	-0.9	1.1	-1.1	-0.3	-1.1	-1.2	-1.0	-0.9	-0.1	-0.9	-0.5	-0.1	-0.6	-1.0	-1.0	0.7	-0.0
Supplements: Calcium	0.3	0.4	3.3	0.6	-0.4	-0.1	0.3	0.1	-1.1	0.0	0.3	-0.5	0.9	0.1	0.1	-0.3	-0.1	-0.1	0.3	1.8	0.5	0.6
Basal cell carcinoma (self-reported)	1.9	2.2	5.6	0.9	2.0	0.9	-1.4	1.6	2.4	0.9	1.1	1.9	-0.4	1.7	1.1	1.6	1.1	-0.3	1.8	-1.9	-1.8	1.4
Heart attack/myocardial infarction (self-reported)	0.4	0.5	4.7	0.1	-0.7	-0.2	0.7	-0.8	-0.7	-0.5	-0.6	-0.4	0.6	-0.8	-0.5	-0.2	-2.2	-0.0	-0.6	0.1	0.4	-0.7
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	2.9	-0.4	0.7	1.3	-1.3	0.8	1.1	0.9	0.7	1.0	-0.5	-0.1	1.1	0.7	-0.3	0.7	0.6	-1.7	-1.3	-0.8
Heart disease (siblings)	0.2	0.2	1.8	0.1	-0.6	-0.0	0.2	-0.5	0.1	-0.0	-0.3	0.0	0.0	-0.8	-0.3	-0.3	-0.7	0.3	-0.6	-0.4	0.1	-1.3
Alcohol drinker status: Previous	0.2	0.2	1.1	-0.5	-0.4	0.2	-0.8	-0.5	-0.2	0.6	-0.0	0.3	1.1	-0.4	0.4	0.2	0.2	0.2	0.3	0.8	-0.1	-0.4
Pack years of smoking	2.2	3.2	11.5	-3.4	-1.5	2.1	0.5	-0.8	-1.7	1.8	2.3	-1.5	-1.3	-2.0	2.0	-1.9	-0.5	2.9	0.7	-0.5	0.6	-2.4
Impedance of whole body	0.2	1.1	5.6	0.2	1.6	-0.4	0.3	0.5	0.8	-0.0	0.4	0.9	2.4	1.1	-0.1	1.0	0.8	-0.9	0.6	1.9	-0.7	1.2
Leg fat mass (left)	1.1	4.4	12.5	-0.6	-1.4	3.5	-2.7	-0.5	-0.3	3.2	2.7	-1.1	-1.7	-1.8	3.2	-1.6	-0.5	3.5	1.0	-1.8	-0.1	-2.7
Arm predicted mass (left)	0.5	2.4	6.1	-0.0	-2.2	1.5	-1.8	-1.5	-1.7	1.5	1.2	-2.5	-0.1	-1.5	1.7	-2.2	-0.0	2.2	-0.2	-0.5	1.4	-1.6