Hub : Genes

WIPI2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Artery Aorta 0.1500 0.0560 4.5e-03 -0.005 NA -0.005 NA -0.003 8.9e-01 NA 9.8e-01 NA 5.3e-01
2 GTEx Testis 0.5770 0.0700 8.4e-09 0.472 NA 0.390 NA 0.440 2.6e-23 NA 1.9e-18 NA 2.3e-21
3 GTEx Thyroid 0.2600 0.0580 6.6e-06 0.129 NA 0.132 NA 0.138 4.8e-10 NA 2.9e-10 NA 1.1e-10
4 GTEx Whole Blood 0.1140 0.0420 6.0e-03 0.019 NA 0.020 NA 0.024 6.8e-03 NA 5.4e-03 NA 2.7e-03
5 NTR Blood 0.0428 0.0137 4.6e-04 0.017 0.016 0.013 0.017 0.014 2.9e-06 4.2e-06 4.6e-05 2.0e-06 1.5e-05
6 ROSMAP Brain Pre-frontal Cortex 0.1291 0.0328 1.3e-05 0.113 0.043 0.116 0.115 0.119 2.6e-14 3.0e-06 9.8e-15 1.4e-14 5.4e-15
7 YFS Blood 0.3080 0.0320 0.0e+00 0.215 0.240 0.256 0.249 0.249 1.9e-68 2.5e-77 2.8e-83 1.1e-80 9.4e-81
8 TCGA Thyroid Carcinoma 0.1650 0.0460 4.3e-10 0.086 0.108 0.085 NA 0.103 9.5e-09 1.2e-10 1.3e-08 NA 3.3e-10

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.4 0.6 1.3 -0.4 0.6 1.1 0.6 -1.1 1.1 -0.8 0.0
Bipolar Disorder or Schizophrenia 1.1 2.7 6.6 0.2 0.6 0.3 -1.5 -2.4 2.6 -2.5 0.4
Depressed Affect (Nagel 2018) 0.6 1.3 4.5 0.3 -0.6 -0.1 -1.2 -0.5 -2.1 1.8 0.8
Depression (Nagel 2018) 1.0 1.5 4.1 -1.4 -1.0 0.5 -2.0 -2.0 0.2 -0.6 -0.2
Intelligence (Savage-Jansen 2018) 0.3 0.9 2.8 0.5 -0.7 0.0 1.6 1.7 -0.3 0.4 0.7
Neuroticism (Nagel 2018) 0.5 1.1 3.2 0.8 -0.5 -1.5 -1.2 -0.1 -1.8 1.1 -0.1
Schizophrenia (2018) 1.0 2.1 6.0 0.3 0.3 -0.5 -0.8 -2.1 2.4 -2.3 0.2
Schizophrenia vs Biploar Disorder 1.0 1.3 4.8 0.0 0.0 1.0 -0.4 -2.2 2.0 0.0 0.0
Worry (Nagel 2018) 0.5 1.0 3.8 0.1 -0.7 -2.0 -1.4 -0.4 -0.7 0.1 -1.0
Alzheimer’s Disease (in mother) 1.7 2.0 10.3 0.2 -0.6 -3.2 0.3 1.2 -1.5 0.8 -0.8
Alzheimer’s Disease (in father) 1.1 1.2 5.7 2.4 -1.4 -1.0 -0.2 0.5 -0.6 -0.1 0.9
Alzheimer’s Disease (including proxy) 1.2 1.8 10.0 1.0 -1.3 -3.2 -0.2 0.4 -1.2 0.0 -0.4
Crohns Disease (2017) 0.2 0.5 2.7 0.7 0.6 0.5 0.1 -1.6 0.3 -0.1 -0.4
Irritable Bowel Disease (IBD) 0.1 0.2 0.7 -0.4 0.5 -0.2 -0.2 -0.9 0.0 0.2 -0.4
Ulcerative Colitis (UC) 0.1 0.2 1.0 -1.0 0.0 -0.2 -0.5 -0.6 -0.1 0.3 0.1
Major Depression (MDD) 0.5 0.6 3.5 0.0 0.0 -0.1 -1.9 0.4 -0.4 0.0 -1.0
Reaction Time 1.2 2.4 7.6 0.2 1.2 0.3 2.8 0.3 -2.0 2.4 0.4
Verbal and Numeric Reasoning (VNR) 0.4 0.9 2.9 -0.2 -1.7 0.7 -0.7 1.1 -0.5 0.4 1.2
Breast Cancer 0.8 1.8 3.6 1.7 1.0 -1.9 -1.1 0.2 1.3 -1.5 -1.5
Ovarian Cancer 0.9 1.2 4.7 2.2 -0.3 1.0 -0.0 -0.3 -0.5 0.7 1.7
Prostate Cancer 0.3 0.5 1.3 -0.1 -0.4 1.0 0.6 -1.1 -0.8 0.5 0.1
Age at First Birth 1.2 1.8 8.1 -2.9 0.6 -0.7 -0.3 -0.1 1.2 -1.4 -1.4
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.5 0.7 2.6 0.0 0.0 0.7 0.2 -0.1 -1.3 1.6 0.6
Coronary Artery Disease (CAD) 0.6 0.7 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 -2.3
Crohns Disease (2012) 0.7 1.2 4.4 1.4 1.0 0.5 -0.3 -2.1 0.9 -0.9 0.1
Mean Putamen Volume 0.5 0.5 1.4 -0.8 0.4 0.2 -0.9 -0.5 -1.2 1.0 -0.3
Fasting Glucose 0.5 0.6 2.7 0.2 0.3 1.6 1.0 -0.1 0.3 -0.1 0.6
HbA1C 0.6 0.6 2.2 -0.5 -0.7 -0.6 1.5 1.0 -0.4 0.7 0.3
HDL Cholesterol 0.3 0.5 2.4 0.2 0.2 0.4 1.5 -0.3 -0.5 0.9 0.4
LDL Cholesterol 0.8 1.3 4.8 -0.5 1.9 0.6 2.2 -0.8 -0.4 0.4 0.3
Lupus 1.3 1.9 6.9 -2.5 0.3 1.0 -0.1 -2.6 0.7 -0.6 -0.6
Neuroticism (2016) 1.0 1.4 5.0 -0.4 -0.3 0.8 -2.1 -2.2 -0.9 0.2 0.2
Primary Biliary Cirrhosis 1.3 1.8 3.8 1.1 -0.8 -1.8 -1.0 -1.8 0.6 -1.2 -2.0
Rheumatoid Arthritis 0.6 0.8 1.9 -1.2 -0.1 -1.0 -0.8 -0.8 -0.7 0.4 -1.4
Schizophrenia (2014) 1.3 2.8 7.4 0.9 0.1 0.5 -0.5 -2.5 2.7 -2.7 0.3
Triglycerides 0.7 1.2 2.9 0.3 1.2 -0.3 0.9 1.4 -1.3 1.7 0.8
Type 2 Diabetes (T2D) (2012) 0.4 0.4 2.2 1.5 0.0 -0.2 0.4 0.8 0.0 0.1 0.7
Ulcerative Colitis 0.1 0.2 0.6 -0.5 0.5 -0.8 -0.1 -0.2 -0.4 0.1 -0.0
Blood Eosinophil Count 0.1 0.8 5.4 -2.3 0.3 0.1 -0.6 -0.2 0.4 -0.7 0.5
Blood Platelet Count 0.1 1.5 4.6 -1.8 0.9 0.2 -2.1 -1.1 1.2 -0.7 -0.7
Blood Red Count 0.8 7.8 26.8 2.3 3.3 -5.2 -1.6 1.3 -2.1 0.6 -3.2
Blood White Count 0.2 1.6 4.6 0.7 -0.7 -1.1 -2.1 1.3 -1.6 1.1 0.5
Heel T-Score 0.1 1.1 3.0 -1.3 0.1 -1.5 -0.8 0.4 -0.3 -0.9 -1.7
BMI 0.4 2.3 7.2 0.5 -0.7 -0.7 -0.8 -1.0 -2.7 2.2 1.9
Height 0.1 2.3 6.4 0.8 -1.3 0.1 1.7 1.7 -2.0 2.5 0.3
Waist Hip Ratio (WHR) 0.2 0.8 2.5 -0.3 0.6 -1.2 0.3 1.6 -0.6 0.7 -1.0
Systolic Blood Pressure 0.2 1.0 3.1 -0.3 -1.6 -0.2 -0.1 0.7 -1.8 1.1 0.2
Smoking Status 1.9 4.5 14.1 0.2 0.3 -2.0 1.1 2.4 -3.8 3.2 0.5
Allergy or Eczema 0.7 1.8 7.6 1.9 0.2 0.6 -0.5 2.8 0.5 0.1 1.4
Cardiovascular Disease 0.2 0.8 4.5 -0.8 0.5 0.3 -0.2 -2.1 -0.8 0.1 -0.3
Hypothyroidism (self reported) 0.8 1.8 9.7 -0.9 0.7 0.4 -1.3 -3.1 0.6 -1.0 -0.2
Respiratory disease 0.4 1.0 4.2 1.3 -0.1 -0.8 -0.9 2.1 -0.4 -0.0 -0.4
Type 2 Diabetes (T2D) (2018) 1.8 3.3 8.4 2.5 2.9 1.6 2.4 0.4 -0.5 1.4 1.2
Lung FEV1/FVC ratio 0.3 1.7 4.3 -0.7 0.8 -0.7 -0.7 -2.1 1.0 -1.6 -1.9
Lung FVC 0.3 1.6 3.0 1.3 0.1 1.7 1.7 0.6 1.5 -1.1 1.2
Neuroticism 0.2 0.5 1.3 0.1 -0.6 -0.0 -1.1 -0.8 -1.1 0.8 0.1
Chronotype (morning person) 0.8 1.7 3.4 0.5 1.7 -1.0 1.8 0.4 -1.8 1.3 -1.1
Hair Pigment 0.1 3.1 7.7 0.9 -0.9 2.8 -0.0 -1.5 2.4 -2.0 1.8
Tanning 0.1 1.2 3.0 -1.2 0.4 -1.7 -1.5 0.1 -1.1 0.1 -1.3
Hand grip strength (left) 0.9 2.3 3.7 1.7 -0.4 -0.8 1.8 1.9 -1.4 1.9 1.5
Number of treatments/medications taken 0.3 0.6 1.2 0.6 0.7 0.1 1.0 0.5 -1.1 1.0 0.5
Average weekly spirits intake 1.2 1.5 5.8 -2.4 -0.9 1.2 -0.9 -1.5 0.7 -0.6 -0.4
Sensitivity / hurt feelings 0.3 0.6 1.7 -0.2 -1.2 -0.5 -0.8 -1.3 -0.2 -0.0 -0.6
Frequency of depressed mood in last 2 weeks 0.7 0.9 2.1 -1.4 -0.6 -0.1 -1.4 -1.1 -0.5 0.3 -1.2
Hearing difficulty/problems: Yes 0.5 0.8 2.0 -1.1 -1.0 -0.1 -1.4 -1.0 -0.1 -0.2 -1.0
Relative age of first facial hair 0.3 0.7 3.3 0.2 -0.4 -0.1 -1.8 0.2 0.7 -0.9 0.7
Other serious medical condition/disability diagnosed by doctor 0.9 1.2 3.0 1.0 1.6 -1.7 0.1 0.2 0.5 -0.3 -1.5
Ever used hormone-replacement therapy (HRT) 0.4 0.5 1.4 0.1 0.4 -0.5 1.1 -0.9 0.3 -0.6 -1.2
Ever had hysterectomy (womb removed) 0.3 0.4 1.2 0.4 -0.6 -0.5 -1.1 0.2 0.6 -0.8 0.2
Systolic blood pressure, automated reading 0.8 2.3 6.6 0.2 -1.2 0.4 0.1 1.2 -2.6 2.5 1.4
Eye problems/disorders: Diabetes related eye disease 1.5 1.7 6.1 0.5 1.9 -2.5 0.8 0.2 -1.1 0.6 -1.2
Angina 1.4 1.8 4.4 1.5 0.0 -0.2 1.1 1.5 -2.1 2.0 0.6
Medication for hormone replacement therapy 0.7 0.8 2.1 1.5 0.1 -1.1 0.8 0.4 -0.8 1.0 -0.7
Vitamin and mineral supplements 1.0 1.4 3.8 -0.1 -0.9 0.2 -0.7 1.1 -1.8 2.0 1.2
Supplements: Zinc 0.5 0.5 1.4 0.1 -0.8 0.8 -1.2 0.1 0.5 -1.0 0.1
Medication: Co-codamol 0.5 0.6 1.9 0.0 0.2 -1.4 0.8 -0.3 -1.1 0.8 -0.3
Medication: Metformin 3.2 4.6 10.1 3.2 2.0 1.2 2.4 1.6 -1.4 1.7 2.7
Diabetes (father) 1.3 1.6 4.6 2.1 1.2 -0.2 1.4 0.6 -1.0 1.6 0.8
Diabetes (mother) 2.8 3.5 13.0 1.7 0.2 3.6 1.6 -0.1 0.7 0.0 3.0
Severe depression (siblings) 0.3 0.4 1.8 1.3 0.1 -0.1 0.2 0.2 0.8 -0.6 0.4
Pack years adult smoking proportion 2.0 3.1 7.6 2.1 0.8 0.9 1.1 1.8 -2.1 2.8 1.4
Impedance of leg (right) 0.6 3.1 10.8 -1.2 0.1 -2.7 -0.4 1.5 0.9 -1.4 -3.3
Leg fat-free mass (left) 0.6 3.0 9.1 1.2 -0.5 0.7 0.5 -0.2 -2.5 3.0 2.5
Trunk fat percentage 1.0 3.9 15.8 -0.4 -0.0 -0.5 -0.2 0.1 -3.7 4.0 1.2
Hand grip strength (right) 0.6 1.6 3.0 1.3 -1.0 -0.2 1.1 1.1 -1.4 1.7 1.7
Townsend deprivation index at recruitment 0.6 0.9 1.8 0.5 -0.5 1.1 -0.8 -0.3 -1.3 1.3 1.0
Current tobacco smoking 2.2 3.6 13.5 0.7 -0.1 -1.9 0.2 1.6 -3.7 2.8 -0.4
Average weekly fortified wine intake 0.3 0.4 1.4 -0.4 -0.5 -0.6 0.2 1.2 -0.7 0.5 0.2
Maternal smoking around birth 0.7 1.0 2.5 0.6 0.5 -1.5 0.1 -0.2 -1.6 0.9 -1.3
Fed-up feelings 1.0 1.8 5.9 0.7 -0.1 0.6 0.4 0.4 -2.4 2.2 1.6
Frequency of unenthusiasm / disinterest in last 2 weeks 1.0 1.3 4.9 -1.1 -0.6 0.8 -1.8 -2.2 0.1 -0.5 -0.1
Relative age voice broke 0.9 1.3 5.0 -0.4 -0.6 -0.3 -2.2 -1.5 0.8 -1.5 -0.3
Taking other prescription medications 0.2 0.3 0.9 -0.5 -0.2 0.5 0.6 -0.3 1.0 -0.5 0.5
Age when periods started (menarche) 0.4 1.1 1.8 1.3 -1.3 0.3 -0.6 -1.3 1.3 -1.1 0.0
Bilateral oophorectomy (both ovaries removed) 0.9 1.0 2.5 1.2 0.3 -1.0 0.5 0.5 -1.5 1.6 0.6
Heel bone mineral density (BMD) T-score, automated (left) 0.9 2.0 6.3 0.5 0.8 -2.5 -1.1 1.4 -1.6 1.1 -1.3
Tinnitus: Yes, but not now, but have in the past 0.4 0.4 2.2 -0.7 1.5 0.4 0.3 -0.2 0.1 -0.1 -0.6
Qualifications: CSEs or equivalent 0.6 0.8 2.6 -0.1 0.7 1.6 1.1 -0.6 -0.5 1.2 0.5
Serious illness, injury or assault to yourself 0.1 0.2 0.5 0.0 0.6 -0.0 0.7 0.2 -0.2 0.1 0.7
High blood pressure 0.5 1.3 2.8 -1.1 1.6 0.4 0.9 -0.8 -1.7 1.4 0.1
Hayfever, allergic rhinitis or eczema 1.2 2.5 9.8 2.6 0.3 -0.2 -1.2 3.1 1.0 -0.5 0.5
Multivitamins +/- minerals 0.6 0.7 2.2 -0.4 -0.5 0.1 0.4 -1.3 1.1 -1.5 -0.3
Stomach or abdominal pain in last month 0.6 0.7 2.9 0.3 1.7 -0.3 1.3 -0.0 0.7 0.1 -0.8
Supplements: Glucosamine 0.4 0.5 1.7 -1.1 1.3 0.6 0.2 -0.4 0.2 0.0 0.6
Diverticular disease/diverticulitis (self-reported) 1.2 1.5 3.0 1.7 1.4 1.3 1.7 -0.9 0.7 -0.4 0.9
Medication: Atenolol 2.0 2.5 6.2 1.6 0.9 -0.7 2.5 1.3 -1.6 2.1 1.2
Medication: Levothyroxine sodium 0.5 0.9 3.6 -1.1 -0.0 0.3 -0.9 -1.9 0.3 -1.2 0.3
Sitting height 0.2 1.4 4.8 1.4 -2.2 -0.9 -0.4 0.4 -1.4 1.1 0.0
Chronic bronchitis/emphysema (father) 1.1 1.3 3.6 1.5 1.9 0.3 1.6 0.6 1.1 -0.2 0.3
High blood pressure (mother) 0.8 1.1 2.3 -0.4 -1.3 0.1 -1.5 -0.3 -1.4 1.1 0.9
Body mass index (BMI) 1.2 5.0 17.1 -0.3 -0.1 0.5 -0.3 -0.6 -4.0 4.1 2.4
Impedance of leg (left) 0.5 2.3 8.7 -1.2 -0.3 -2.1 -0.7 0.6 0.9 -1.5 -2.9
Leg predicted mass (left) 0.6 3.2 9.7 1.2 -0.5 0.7 0.5 -0.1 -2.5 3.1 2.6
Trunk fat mass 1.2 5.0 20.0 -0.0 -0.4 -0.3 0.0 0.2 -4.1 4.5 1.9
Waist circumference 1.0 3.7 12.9 -0.6 -0.0 0.4 0.0 -0.4 -3.4 3.6 2.1
Number of incorrect matches in round 1.4 2.3 5.6 0.3 2.3 2.4 2.0 -1.1 0.6 -0.2 1.4
Past tobacco smoking 1.6 3.0 10.7 1.1 -0.8 0.0 -1.2 -0.7 3.1 -3.3 -0.5
Alcohol usually taken with meals 1.3 2.1 5.8 2.4 -0.5 0.0 0.3 0.3 2.4 -2.2 0.2
Nervous feelings 0.9 1.7 4.8 -1.3 -0.3 0.5 -0.9 -2.2 1.4 -1.7 -1.1
Frequency of tenseness / restlessness in last 2 weeks 0.6 0.9 2.1 -1.3 0.5 -1.0 -0.4 -1.4 -0.3 -0.1 -1.3
Hearing difficulty/problems with background noise 0.3 0.5 1.9 0.1 -0.7 0.9 -0.6 -1.4 0.4 -0.1 0.2
Hair/balding pattern: Pattern 2 0.4 0.5 3.1 -1.8 0.3 0.2 0.3 -0.9 0.1 -0.2 -0.4
Had menopause 2.4 3.0 6.5 -1.8 1.2 1.4 -0.2 -2.0 2.6 -2.5 -0.8
Had other major operations 0.5 0.6 2.4 0.5 1.1 -0.7 0.2 0.1 0.5 -0.3 -1.6
Forced vital capacity (FVC) 0.2 1.0 3.4 0.8 -1.0 0.4 -0.2 0.4 1.9 -1.5 -0.0
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.4 4.2 0.3 0.9 -2.0 -0.5 1.4 -1.5 1.1 -0.6
Ever unenthusiastic/disinterested for a whole week 0.7 0.9 4.1 0.7 -1.0 -0.1 -0.2 2.0 -0.6 0.9 0.2
Qualifications: None of the above 0.4 0.9 3.7 0.3 1.9 -0.4 1.5 -0.5 -0.1 0.4 -0.7
Financial difficulties in last 2 years 0.9 1.2 4.5 0.3 -0.6 -1.4 0.3 1.0 -2.1 1.3 0.2
Mouth/teeth dental problems 1.9 2.9 10.0 -0.2 -0.2 0.7 -0.7 -2.1 2.6 -3.2 -0.7
Heart attack 0.3 0.3 1.2 -1.1 0.8 -0.1 -0.6 0.6 -0.4 0.0 -0.0
Allergy 1.0 2.2 11.4 -1.8 0.6 0.6 1.4 -3.4 0.3 -0.4 -0.0
Pain all over the body in last month 0.3 0.3 0.9 -0.2 -0.3 -0.3 -1.0 0.5 -0.0 -0.1 -0.9
Diabetes (self-reported) 2.7 4.2 10.3 3.2 2.8 0.0 2.3 1.6 -1.7 2.0 0.6
Hayfever/allergic rhinitis (self-reported) 1.9 2.6 10.2 2.7 0.0 0.2 -0.5 3.2 0.7 -0.6 1.4
Medication: Ramipril 1.3 1.7 4.7 2.0 0.4 1.4 0.7 0.9 -0.9 0.9 2.2
Medication: Simvastatin 0.5 0.7 1.6 1.3 1.1 0.4 1.1 0.2 -0.7 0.8 0.5
Fluid intelligence score 0.1 0.1 0.2 0.2 -0.5 0.4 0.3 0.4 -0.3 0.4 -0.2
Illnesses of siblings 1.4 2.0 4.0 -0.6 -1.2 -1.0 -2.0 1.3 1.3 -1.8 -1.5
Neuroticism score 0.4 0.9 2.5 0.3 -0.4 -0.3 -0.7 -1.3 -1.6 1.4 0.3
Weight 0.9 4.5 15.8 -0.2 -1.0 0.2 -0.3 -0.4 -3.8 4.0 2.2
Impedance of arm (right) 0.7 3.2 10.6 -0.8 1.0 -1.9 0.6 0.1 2.1 -2.2 -3.3
Arm fat percentage (right) 1.0 4.1 15.4 -0.7 0.3 -0.5 -0.1 -0.4 -3.9 3.9 1.3
Trunk fat-free mass 0.4 2.4 5.6 0.5 -1.7 0.4 0.1 -0.2 -2.2 2.4 2.3
Hip circumference 0.7 3.1 10.2 0.2 0.1 0.1 -0.2 -1.2 -3.2 3.2 1.7
Time employed in main current job 1.2 1.4 4.9 1.6 0.5 -1.5 0.3 2.2 -0.3 0.6 -0.6
Alcohol intake versus 10 years previously 0.8 1.2 2.1 1.0 1.1 1.5 0.9 -0.4 -1.3 1.4 1.0
Father’s age at death 1.2 1.6 3.6 0.6 -1.1 1.9 0.4 -0.5 1.5 -1.5 1.7
Worrier / anxious feelings 0.2 0.4 0.7 -0.1 -0.8 -0.8 -0.6 0.1 -0.5 0.6 -0.7
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.7 3.0 0.5 1.3 0.4 1.7 -0.6 0.3 0.1 -0.4
Falls in the last year 1.7 2.3 8.0 -0.7 1.0 -1.4 0.5 -0.4 -2.8 2.5 -0.8
Hair/balding pattern: Pattern 3 0.4 0.6 2.3 0.3 -1.5 -0.4 -0.8 0.5 -1.2 0.6 0.2
Number of live births 0.4 0.5 1.3 -0.9 0.9 0.5 0.1 -0.1 1.0 -1.2 -0.2
Forced expiratory volume in 1-second (FEV1) 0.3 1.1 4.5 0.6 -0.2 -0.2 0.2 -0.1 2.1 -1.8 -0.8
Pulse rate 1.0 1.7 6.9 0.6 -2.6 0.2 -1.3 1.5 -1.2 0.9 0.4
Happiness 0.4 0.4 1.1 -0.7 -0.6 -0.7 -0.1 1.0 -0.6 0.4 0.7
Noisy workplace 0.4 0.5 1.3 -0.4 0.5 -0.6 -0.5 -0.5 0.8 -1.1 -1.0
Qualifications: A levels/AS levels or equivalent 1.4 3.2 12.0 0.7 -3.5 -1.3 -1.8 2.7 -0.3 -0.4 0.8
Serious illness, injury or assault of a close relative in last 2 years 0.7 0.8 2.3 -0.9 0.8 0.5 0.9 0.6 1.5 -1.1 -0.3
Mouth/teeth dental problems: Dentures 2.2 3.8 10.4 -0.1 2.2 -1.0 1.7 1.9 -2.7 3.2 0.3
Asthma 0.9 1.8 8.5 1.6 -0.0 -0.7 -1.7 2.9 -0.3 0.1 -0.1
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 1.2 0.6 0.4 -0.3 0.5 1.1 -0.9 0.9 0.7
Medication: Cholesterol lowering 0.9 1.5 2.5 1.2 0.7 0.9 1.4 1.0 -1.5 1.6 1.2
Depression (self-reported) 1.9 2.3 5.1 -1.6 1.8 -1.4 1.1 -0.8 -2.2 2.0 -0.6
Medication: Lansoprazole 1.0 1.1 2.9 -1.7 -0.3 1.2 1.2 -0.2 -0.7 1.2 0.9
Prospective memory result 0.1 0.2 0.6 0.1 0.8 0.2 0.5 -0.0 0.4 -0.5 -0.1
Lung cancer (father) 1.1 1.3 3.3 0.2 1.8 0.9 0.8 1.7 -0.6 1.2 0.8
Illnesses of mother 0.6 0.7 2.6 -0.2 -0.2 0.6 -0.7 0.1 1.6 -1.3 -0.6
Forced expiratory volume in 1-second (FEV1), Best measure 0.6 1.9 7.3 -0.2 -0.6 0.1 -0.5 -0.7 2.6 -2.7 -0.5
Pulse wave Arterial Stiffness index 0.6 0.7 1.6 1.0 -0.6 1.3 0.1 -1.2 -0.2 0.2 0.8
Impedance of arm (left) 0.5 2.3 7.7 -0.5 0.3 -1.5 0.2 0.5 2.0 -2.1 -2.8
Arm fat mass (right) 1.2 4.8 17.5 -0.3 -0.3 -0.2 -0.2 -0.1 -4.1 4.2 1.9
Trunk predicted mass 0.4 2.5 5.5 0.6 -1.8 0.4 0.0 -0.1 -2.2 2.3 2.3
Standing height 0.1 0.5 3.1 -0.0 -1.8 -0.7 0.2 0.3 -0.0 0.2 -0.5
Length of working week for main job 0.7 0.8 2.3 -0.6 0.4 -0.9 0.6 -0.7 -1.4 1.5 -0.5
Exposure to tobacco smoke at home 0.4 0.5 1.9 0.0 0.6 -0.3 -0.1 0.6 -1.4 0.9 0.2
Breastfed as a baby 0.8 1.0 3.3 -0.4 -0.4 -0.8 0.3 0.4 1.8 -1.7 0.6
Tense / ‘highly strung’ 0.9 1.4 4.0 -0.4 -0.8 -1.0 -0.5 1.6 -2.0 1.6 0.5
Seen doctor (GP) for nerves, anxiety, tension or depression 1.1 1.7 5.6 -0.3 -1.1 -1.5 -0.3 0.8 -2.4 2.0 0.2
Hair/balding pattern: Pattern 4 0.1 0.3 1.1 0.5 1.1 0.3 0.3 0.0 0.7 -0.7 0.1
Birth weight of first child 0.7 1.3 4.9 0.4 -0.3 -2.1 -0.1 -0.4 -0.6 0.2 -2.2
Peak expiratory flow (PEF) 0.3 0.7 2.3 -0.8 0.0 0.9 0.3 -1.5 1.1 -0.8 -0.2
Pulse wave reflection index 1.0 1.3 3.0 0.5 0.1 1.7 -0.1 -1.1 1.5 -1.2 1.4
Ever highly irritable/argumentative for 2 days 1.5 1.7 4.3 -1.4 -0.3 -1.6 -1.2 -0.5 -1.4 1.1 -2.1
Loud music exposure frequency 1.1 1.2 5.3 1.3 0.7 2.3 -0.0 0.6 -0.1 0.8 1.2
Qualifications: O levels/GCSEs or equivalent 0.3 0.5 1.8 0.6 -1.4 0.5 -1.0 0.5 -0.1 0.1 -0.1
Mouth/teeth dental problems: Bleeding gums 0.5 0.7 1.8 -0.7 -0.2 -0.9 0.1 0.4 -1.3 1.4 -0.3
Blood clot in the leg (DVT) 1.3 1.6 3.8 -1.9 0.1 0.2 1.0 -0.9 -2.0 1.9 -0.0
Medication: Paracetamol 0.4 0.6 2.4 -0.1 -0.3 0.4 0.7 0.4 -1.3 1.6 0.2
Headache pain in last month 0.1 0.3 1.1 0.2 -0.1 -1.0 -0.1 -0.2 -0.4 0.3 -0.8
Medication for cholesterol, blood pressure or diabetes 0.7 1.2 4.1 0.3 -1.1 0.2 -0.9 0.1 2.0 -1.8 0.8
Glaucoma (self-reported) 1.1 1.3 5.0 0.6 1.4 -0.9 2.2 1.2 -0.2 0.8 0.6
Gout (self-reported) 1.1 1.5 4.7 -0.0 -0.1 -0.0 1.2 1.3 -1.9 2.2 0.7
Hypothyroidism/myxoedema (self-reported) 1.1 2.2 10.2 -1.2 0.6 1.6 -0.6 -3.2 0.9 -1.1 0.5
Medication: Amlodipine 0.3 0.4 1.4 0.4 0.1 0.0 -0.2 0.0 -1.1 1.2 0.0
Medication: Ventolin 100micrograms inhaler 0.8 1.1 3.0 1.5 -0.4 -1.0 -0.7 0.6 -1.7 1.1 0.4
Birth weight 0.5 1.1 3.6 0.7 0.2 1.9 1.5 -0.5 1.1 0.1 1.0
Chronic bronchitis/emphysema (mother) 1.0 1.2 3.5 -0.4 1.7 -1.9 -0.0 0.2 -0.0 -0.0 -1.8
High blood pressure (siblings) 2.1 3.1 8.5 0.4 1.7 0.3 2.9 -1.3 -2.0 2.6 0.5
Forced vital capacity (FVC), Best measure 0.4 1.4 4.6 0.2 -1.3 0.4 -0.4 -0.1 2.1 -2.1 0.4
Body fat percentage 1.1 4.4 17.2 -0.7 0.1 -0.5 -0.3 0.0 -3.9 4.2 1.4
Leg fat percentage (right) 1.2 4.5 16.0 -0.9 0.1 -0.4 -0.2 0.6 -4.0 4.0 1.6
Arm fat-free mass (right) 0.8 4.0 10.0 0.7 -1.7 0.9 -0.3 0.0 -2.9 3.1 3.2
Exposure to tobacco smoke outside home 1.1 1.4 5.7 -0.1 0.8 0.1 0.7 0.2 -2.0 2.4 0.8
Comparative body size at age 10 0.9 2.5 6.7 0.0 -1.2 0.9 -1.7 1.1 -2.4 2.6 0.9
Number of full brothers 1.4 1.8 5.4 1.0 1.3 -1.6 0.5 0.1 -2.3 1.9 0.4
Worry too long after embarrassment 0.3 0.5 1.4 1.0 0.4 0.6 0.5 -1.2 0.6 -0.4 0.2
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.6 1.5 -0.9 -0.2 -0.9 -0.3 -1.2 -0.8 0.6 -0.7
Wheeze or whistling in the chest in last year 1.6 2.8 9.3 2.1 0.3 -0.6 0.3 3.0 -1.9 2.1 0.7
Number of children fathered 0.2 0.2 0.6 -0.8 0.6 0.2 0.7 -0.1 -0.1 0.2 -0.3
Reason for reducing amount of alcohol drunk: Health precaution 0.7 0.8 2.0 -0.5 -1.4 0.4 -0.9 -0.1 1.2 -1.1 -0.6
Age at first live birth 0.2 0.3 0.9 0.9 -0.8 -0.1 0.9 -0.5 0.4 -0.0 0.0
Pulse wave peak to peak time 0.5 0.6 1.3 -1.2 0.5 -1.1 0.0 1.1 0.1 -0.0 -0.7
Health satisfaction 0.8 1.0 4.6 1.0 -0.4 -2.1 -0.0 0.9 0.1 -0.3 -1.3
Shortness of breath walking on level ground 0.5 0.6 1.3 1.1 -1.0 -1.0 -0.7 0.8 -0.1 -0.1 -0.3
Qualifications: College or University degree 0.9 3.0 10.4 0.7 -1.4 0.4 -1.7 0.3 2.9 -3.2 -0.1
Eye problems/disorders: None of the above 1.6 1.9 4.9 0.5 -1.5 1.8 -2.2 -0.8 1.2 -1.4 0.6
Mouth/teeth dental problems: Loose teeth 0.5 0.6 1.5 0.1 -0.7 1.2 0.4 0.7 0.7 -0.5 1.0
Emphysema/chronic bronchitis 0.6 0.7 1.6 1.2 0.2 0.7 0.8 0.8 -0.8 0.7 1.0
Medication for pain relief, constipation, heartburn 1.1 1.8 5.3 -1.1 -0.5 0.6 -0.9 -1.3 2.1 -2.3 -0.4
Neck or shoulder pain in last month 0.6 0.9 2.6 -0.6 0.7 0.4 0.3 -1.2 -1.3 1.6 0.4
Medication: Blood pressure 1.0 1.7 4.8 -0.6 1.4 -0.4 1.2 -0.2 -2.2 2.1 -0.7
Angina (self-reported) 1.5 2.0 5.1 1.3 0.1 -0.2 1.3 1.5 -2.2 2.1 0.7
Migraine (self-reported) 1.1 1.4 2.8 1.0 -1.5 1.0 -1.7 0.2 0.9 -0.8 1.6
Medication: Ibuprofen 0.7 0.9 3.0 1.2 0.2 -0.6 0.4 1.7 -0.8 0.9 0.7
Medication: Allopurinol 0.5 0.7 1.8 0.7 -0.7 0.2 0.3 1.3 1.2 -0.8 0.7
Medication: Omeprazole 2.0 2.3 7.3 -1.6 -0.9 -1.2 0.5 1.1 -2.7 2.3 -0.0
Medication: Seretide 50 evohaler 0.2 0.2 0.8 0.4 -0.2 0.3 0.0 0.5 -0.9 0.7 -0.1
Mean time to correctly identify matches 1.0 2.0 7.7 0.2 1.0 0.9 2.8 0.1 -1.5 2.0 0.6
Heart disease (mother) 1.0 1.2 5.6 0.6 1.7 0.0 2.4 -0.0 0.1 0.1 0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.3 0.3 0.7 0.1 -0.8 -0.6 0.4 0.7 -0.1 0.6 -0.8
Whole body fat mass 1.2 4.9 18.6 -0.1 -0.4 -0.2 -0.3 -0.1 -4.1 4.3 1.9
Leg fat mass (right) 1.4 5.6 20.8 -0.3 -0.3 -0.5 -0.3 0.4 -4.5 4.6 1.8
Arm predicted mass (right) 0.8 3.9 9.5 0.8 -1.8 1.0 -0.4 0.2 -2.8 3.0 3.1
Pulse rate, automated reading 0.3 1.1 3.0 1.0 -1.7 -0.0 -1.0 1.1 -1.1 0.3 1.1
Alcohol intake frequency. 0.6 1.3 3.7 0.3 -0.2 0.2 0.2 0.4 -1.9 1.9 1.8
Comparative height size at age 10 0.0 0.1 0.3 -0.2 -0.5 -0.5 0.3 0.1 0.2 -0.1 -0.6
Number of full sisters 0.8 1.0 3.0 -1.7 -0.6 -0.5 -0.8 -1.5 0.1 -1.0 -0.6
Suffer from ‘nerves’ 0.4 0.6 2.0 -1.4 -0.8 -0.2 -0.9 -1.1 0.2 -0.6 -0.1
Overall health rating 1.0 2.1 7.3 1.5 0.4 -0.7 -0.5 0.8 -2.3 2.7 0.3
Chest pain or discomfort 0.7 1.1 3.8 1.4 -0.4 -1.1 0.3 1.9 -0.8 0.8 0.2
Had major operations 0.9 1.1 3.0 0.7 -1.4 0.0 -1.6 1.7 -0.6 0.7 0.4
Age at last live birth 0.3 0.4 1.2 0.6 -1.1 -0.7 0.6 0.2 -0.1 0.1 -0.8
Family relationship satisfaction 0.3 0.3 1.2 -0.4 -1.1 -0.0 -0.7 0.7 0.3 0.1 0.6
Leg pain on walking 0.7 0.9 2.6 -1.5 -0.4 -0.5 -1.6 -1.0 -0.3 -0.0 -1.0
Qualifications: NVQ or HND or HNC or equivalent 2.1 2.5 8.8 1.3 -0.9 -0.3 0.7 -0.4 -3.0 2.8 0.4
Commuting to job workplace: Car/motor vehicle 0.1 0.2 0.5 0.6 0.1 0.2 0.7 0.4 -0.1 0.3 0.2
Illness, injury, bereavement, stress in last 2 years 0.4 0.5 2.3 0.5 0.1 0.9 -0.5 -1.5 0.6 -0.5 -0.1
Medication: Aspirin 1.1 1.4 3.4 0.4 1.5 0.2 1.4 -0.2 -1.7 1.8 0.8
Supplements: Vitamin C 0.3 0.4 1.1 -0.3 -0.2 0.2 0.2 1.0 1.0 -0.7 -0.4
Knee pain experienced in last month 1.5 2.4 6.5 0.4 2.5 -0.8 2.3 -0.0 -1.2 2.2 -0.4
Hypertension (Self-reported) 0.5 1.4 3.4 -1.2 1.8 -0.3 0.7 -0.7 -1.8 1.4 -0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.7 2.0 9.3 -3.0 -0.5 -1.1 -0.6 -1.6 -0.4 -0.1 -1.3
Illnesses of father: Heart disease 1.0 1.4 5.1 1.0 0.8 0.9 2.3 -1.4 -0.6 1.1 0.5
Illnesses of siblings: Diabetes 0.9 1.1 2.9 0.5 -0.0 0.8 1.4 -0.6 -1.0 1.3 1.7
Smoking status: Previous 0.6 0.9 2.9 -0.8 0.3 0.1 0.4 0.2 -1.6 1.7 0.6
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.3 3.6 -0.5 -1.9 -1.6 0.1 -1.0 0.3 -0.4 -1.5
Whole body fat-free mass 0.5 2.8 7.2 0.8 -1.2 0.9 0.3 -0.3 -2.2 2.6 2.7
Leg fat-free mass (right) 0.5 2.9 8.1 1.2 -0.9 1.4 0.2 -0.7 -2.0 2.5 2.9
Arm fat percentage (left) 1.1 4.5 16.7 -0.4 0.0 -0.1 -0.2 -0.2 -4.0 4.1 1.8
Average weekly red wine intake 0.9 1.4 4.0 -0.9 -1.2 -0.8 -2.0 0.0 1.0 -1.4 -1.0
Handedness (chirality/laterality): Left-handed 0.4 0.5 1.1 -0.4 -0.6 -1.0 0.4 -0.7 -1.0 0.6 -0.7
Mood swings 1.3 2.4 8.6 1.2 -1.0 0.1 -0.4 -0.0 -2.9 2.8 0.7
Loneliness, isolation 0.7 1.0 2.8 -0.8 -0.5 1.6 -1.7 -1.0 -0.1 0.2 0.8
Long-standing illness, disability or infirmity 0.6 0.9 3.2 0.1 0.7 -1.8 -1.0 0.2 -0.8 0.7 -0.9
Ever had bowel cancer screening 1.4 1.7 4.4 1.3 -1.0 1.3 1.6 -0.3 -0.8 1.2 2.1
Diabetes diagnosed by doctor 2.7 4.4 10.3 3.2 2.5 0.4 2.3 2.0 -1.9 2.3 1.1
Ever had stillbirth, spontaneous miscarriage or termination 0.6 0.6 2.1 0.1 -0.8 1.2 0.1 -0.0 -0.7 0.6 1.4
Friendships satisfaction 0.2 0.2 0.9 -0.5 0.3 0.0 -1.0 0.0 -0.0 0.3 0.4
Qualifications: nursing, teaching 0.4 0.7 2.2 0.9 -1.5 -0.5 -0.9 1.2 0.2 0.1 0.1
Commuting to job workplace: Walk 0.4 0.5 2.9 -0.3 0.4 0.6 1.7 -0.4 -0.3 0.4 -0.0
Eye problems/disorders: Cataract 0.6 0.7 3.0 -0.9 1.0 -0.3 1.7 0.3 0.2 0.2 -0.3
Mouth/teeth dental problems: Mouth ulcers 0.3 0.4 1.2 -0.4 -1.1 0.5 -1.0 -0.7 -0.0 0.1 0.7
Medication for cholesterol 0.2 0.4 0.9 0.6 -0.9 -0.8 -0.3 0.7 -0.0 -0.2 -0.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.5 0.6 2.4 0.6 -0.0 0.1 0.4 0.4 -1.2 1.6 0.3
Back pain experienced in last month 0.7 1.0 2.9 -0.5 1.3 0.4 0.2 -1.7 1.0 -1.2 -0.4
Mineral and other dietary supplements 0.8 1.1 2.9 1.7 -0.7 0.2 -0.7 1.2 -0.7 0.7 1.7
Breast cancer (self-reported) 0.7 0.8 2.1 -0.7 0.6 -0.5 1.0 -0.1 -1.4 1.4 -0.5
Asthma (self-reported) 1.2 2.3 10.5 1.9 -0.2 -0.9 -1.6 3.2 -0.7 0.4 -0.1
Osteoporosis (self-reported) 1.2 1.5 4.2 0.2 -0.9 -1.6 -2.1 1.7 -0.7 -0.2 -0.7
Osteoarthritis (self-reported) 0.9 1.1 3.1 0.1 1.8 0.9 0.9 -1.5 0.5 -0.0 1.4
Medication: Aspirin 1.4 1.8 4.2 1.1 1.8 -0.4 1.4 -0.1 -1.9 2.0 0.4
Medication: Gliclazide 2.3 2.6 9.5 2.4 1.3 0.6 3.1 0.5 -0.5 1.0 1.4
Illnesses of father: None of the above (group 1) 1.3 1.6 4.9 -1.6 -0.4 -0.3 -2.2 1.3 1.0 -0.6 -1.3
Smoking status: Current 2.0 3.2 11.8 0.7 0.3 -1.8 0.4 1.6 -3.4 2.7 -0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.9 1.9 5.2 -2.3 -0.0 -0.7 0.2 -1.0 1.7 -2.0 -1.0
Whole body water mass 0.5 2.8 7.2 0.7 -1.1 0.9 0.3 -0.3 -2.3 2.7 2.7
Leg predicted mass (right) 0.6 2.9 7.9 1.3 -0.8 1.3 0.3 -0.6 -2.1 2.6 2.8
Arm fat mass (left) 1.2 5.1 17.8 -0.3 -0.6 0.1 -0.4 -0.3 -4.1 4.2 2.2
Number of self-reported non-cancer illnesses 0.3 0.6 2.0 -1.0 1.0 0.3 -0.3 -1.4 0.4 -0.5 0.3
Average weekly champagne plus white wine intake 0.8 1.2 3.3 -0.6 0.6 -0.8 -0.6 -0.7 1.8 -1.8 -0.8
Miserableness 0.9 1.5 4.2 1.4 -0.4 0.3 0.9 0.6 -1.7 2.0 1.3
Guilty feelings 0.7 1.0 3.1 -0.4 1.7 -1.0 0.5 -1.8 0.0 -0.7 -0.7
Wears glasses or contact lenses 0.9 1.0 2.5 -1.0 0.1 1.1 -0.2 -1.3 1.6 -1.3 0.2
Ever taken oral contraceptive pill 1.2 1.3 3.1 1.0 -0.0 -1.7 -0.9 -0.8 -1.3 0.8 -1.5
Hearing aid user 1.1 1.2 2.8 -1.6 0.0 -0.3 -1.7 -0.0 0.9 -0.9 -1.5
Mother’s age at death 1.2 1.5 4.7 -0.3 -2.2 1.7 -1.1 0.8 0.6 -1.0 1.2
Financial situation satisfaction 1.0 1.2 4.5 1.1 0.2 -1.3 -0.6 2.1 -1.0 0.6 0.6
Tinnitus: Yes, now most or all of the time 0.8 0.9 3.0 -0.3 0.5 -1.0 1.7 -0.5 0.6 -0.2 -1.5
Commuting to job workplace: Public transport 0.6 0.7 1.9 0.2 -0.1 1.0 -1.2 1.4 0.5 -0.4 0.5
Eye problems/disorders: Glaucoma 2.2 2.6 6.6 0.7 1.0 -1.0 2.3 1.1 -2.1 2.6 0.8
Medication: Blood pressure 0.3 0.7 2.5 -1.6 1.0 0.6 0.7 -0.3 -0.5 0.6 0.5
Pain type(s) experienced in last month: Hip pain 0.8 1.0 3.2 -1.3 1.8 0.2 0.6 -1.2 0.6 -0.2 -0.9
Supplements: Fish oil (including cod liver oil) 0.6 0.7 2.0 -1.3 0.6 0.4 0.7 -1.2 0.2 -0.0 -1.4
High cholesterol (Self-reported) 0.3 0.5 1.4 0.1 1.0 0.6 1.2 -0.7 -0.4 0.1 0.6
Medication: Bendroflumethiazide 0.7 1.0 2.1 -1.1 1.4 -1.3 -0.3 -0.1 -1.2 0.6 -1.2
Medication: Paracetamol 0.6 0.9 3.4 -0.4 -0.1 0.4 0.7 0.8 -1.4 1.9 -0.4
Medication: Lisinopril 0.3 0.3 1.2 -0.4 -0.0 -0.5 0.6 -0.5 -0.6 0.2 -1.1
Medication: Atorvastatin 0.7 0.9 2.8 -0.2 0.5 -1.0 0.3 1.7 -1.4 1.0 0.3
Illnesses of father: High blood pressure 0.7 0.8 4.2 0.2 -1.1 -0.2 -0.7 -2.0 -0.9 0.1 0.3
Alcohol drinker status: Never 0.7 0.8 2.4 -1.6 -0.9 -0.5 -1.3 -0.1 -0.8 0.6 0.4
Ever smoked 1.2 2.1 7.8 -0.7 0.3 -0.5 0.6 0.6 -2.8 2.8 0.2
Basal metabolic rate 0.6 3.3 9.4 0.6 -1.2 0.7 0.0 -0.3 -2.8 3.1 2.6
Leg fat percentage (left) 1.2 4.2 14.5 -0.8 -0.2 0.1 -0.5 -0.1 -3.8 3.7 2.1
Arm fat-free mass (left) 0.7 3.6 9.7 0.4 -1.3 0.6 -0.4 -0.2 -3.0 3.1 2.7
Number of operations (self-reported) 0.5 0.7 2.7 -0.1 1.0 -1.0 -0.2 0.5 0.8 -0.5 -1.6
Average weekly beer plus cider intake 0.3 0.4 0.7 -0.8 0.6 -0.8 0.8 -0.3 -0.2 0.2 -0.7
Irritability 1.9 3.2 12.3 -0.3 -0.4 -0.6 -0.6 0.7 -3.4 3.5 0.8
Risk taking 0.4 0.6 2.3 0.4 1.0 -0.2 1.5 0.1 -0.4 0.5 -1.0
Ever had prostate specific antigen (PSA) test 0.7 0.8 2.2 -0.1 -1.4 -1.5 -0.6 1.4 0.2 -0.1 0.0
Fractured/broken bones in last 5 years 0.4 0.5 1.3 -0.6 -0.3 -1.0 -0.3 0.5 -1.1 0.9 -0.4
Age started oral contraceptive pill 0.4 0.5 1.4 -0.4 -0.6 -0.4 0.7 0.3 -0.7 0.8 1.2
Diastolic blood pressure, automated reading 1.1 3.5 7.6 1.0 -2.6 -0.0 -1.0 0.6 -2.8 2.4 2.4
Ever depressed for a whole week 1.4 1.8 7.8 -0.3 -1.8 1.1 -2.8 0.6 -1.0 0.4 0.5
Unable to work because of sickness or disability 0.4 0.6 1.1 0.8 -0.1 -0.9 -0.7 0.8 -1.1 0.8 0.3
Commuting to job workplace: Cycle 0.9 1.1 3.0 0.5 0.4 0.2 1.7 1.0 -1.1 1.3 1.0
Myopia 0.8 1.2 2.9 -1.4 -0.5 0.5 -0.8 -0.8 1.4 -1.7 -0.8
Vascular/heart problems diagnosed by doctor 0.4 1.0 2.7 0.9 -1.6 0.0 -0.4 0.3 1.6 -1.2 0.2
Cholesterol lowering medication 0.8 1.1 2.3 -0.9 1.5 0.6 1.4 0.1 -0.8 0.9 1.4
Medication: Omeprazole (e.g. Zanprol) 2.0 2.5 7.5 -1.1 -0.4 -0.9 1.0 1.4 -2.7 2.5 0.9
Pain experienced in last month 0.4 0.7 2.2 0.9 -1.5 0.8 0.0 0.7 -0.5 0.1 1.2
Supplements: Calcium 0.8 0.8 2.2 0.5 0.3 0.8 -1.2 0.0 1.4 -1.5 -0.4
Basal cell carcinoma (self-reported) 0.7 0.8 2.8 -0.3 -0.9 -0.4 -0.1 1.7 -1.3 1.0 0.3
Heart attack/myocardial infarction (self-reported) 0.4 0.5 2.2 -1.5 0.8 -0.3 -0.6 0.2 -0.5 0.1 -0.4
Deep venous thrombosis (DVT) (self-reported) 1.2 1.6 4.2 -1.6 0.1 0.5 1.2 -0.6 -1.9 2.0 0.1
Heart disease (siblings) 0.6 0.8 3.6 -0.0 -0.2 1.9 0.6 0.4 0.1 0.3 1.4
Alcohol drinker status: Previous 0.5 0.6 1.5 1.2 -0.4 -0.9 0.4 1.1 -0.4 0.3 0.7
Pack years of smoking 1.9 2.8 6.1 2.2 1.0 1.1 1.1 1.9 -1.7 2.5 1.4
Impedance of whole body 0.6 3.0 10.0 -0.7 0.1 -2.0 -0.3 0.6 2.0 -2.3 -3.2
Leg fat mass (left) 1.4 5.4 19.7 -0.3 -0.4 -0.1 -0.4 -0.0 -4.4 4.4 2.1
Arm predicted mass (left) 0.7 3.5 9.4 0.4 -1.4 0.6 -0.1 -0.1 -2.9 3.1 2.8