TWAS hub - WIT1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0199	0.0114	0.00063	0.012	0.010	0.009	NA	0.010	0.0014	0.0028	0.0047	NA	0.0025
2	TCGA	Prostate Adenocarcinoma	0.0481	0.0292	0.00870	0.010	0.019	0.019	NA	0.016	0.0270	0.0037	0.0042	NA	0.0080

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Birth weight	7.9	17.2	26.6	-5.2	-2.8
Birth weight of first child	7.7	13.9	23.8	-4.9	-2.0
Medication: Blood pressure	7.2	12.8	19.1	4.4	2.5
High blood pressure	5.8	16.2	17.6	4.2	3.8
Medication: Omeprazole (e.g. Zanprol)	5.7	6.9	7.7	-2.5	-2.8
High blood pressure (mother)	5.4	7.6	8.8	3.0	2.5
Hypertension (Self-reported)	5.4	15.1	15.4	3.9	3.9
Prostate Cancer	5.3	7.4	12.4	-3.5	-1.5
Illnesses of father: High blood pressure	5.1	6.3	10.2	1.6	3.2
Breastfed as a baby	4.8	6.0	8.3	-2.9	-1.9
Vascular/heart problems diagnosed by doctor	4.8	13.1	14.7	-3.8	-3.4
Waist Hip Ratio (WHR)	4.7	21.2	28.2	-5.3	-3.8
Diverticular disease/diverticulitis (self-reported)	4.2	5.0	6.9	-1.7	-2.6
Bilateral oophorectomy (both ovaries removed)	3.9	4.5	8.5	2.9	0.7
Medication: Atenolol	3.9	4.9	8.2	2.9	1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.9	4.6	5.6	-2.4	-1.9
Osteoarthritis (self-reported)	3.9	5.1	10.1	-0.1	3.2
Average weekly beer plus cider intake	3.9	5.6	6.5	-2.2	-2.5
Cardiovascular Disease	3.7	12.1	12.2	3.5	3.5
Chronic bronchitis/emphysema (father)	3.7	4.3	7.3	-2.7	-1.1
Shortness of breath walking on level ground	3.7	4.4	7.4	1.2	2.7
Qualifications: CSEs or equivalent	3.6	4.8	8.2	1.1	2.9
Medication: Bendroflumethiazide	3.6	5.4	8.6	1.5	2.9
Body Mass Index (BMI) (2010)	3.5	4.8	6.1	2.5	1.9
Hayfever/allergic rhinitis (self-reported)	3.5	4.6	7.4	-1.3	-2.7
Medication for cholesterol, blood pressure or diabetes	3.4	5.6	10.1	-3.2	-1.0
Handedness (chirality/laterality): Left-handed	3.4	4.1	7.7	-0.7	-2.8
Age at First Birth	3.3	4.7	6.4	-1.8	-2.5
Systolic Blood Pressure	3.3	16.6	22.1	4.7	3.3
Impedance of arm (right)	3.2	15.1	24.7	-5.0	-2.3
Medication: Blood pressure	3.1	5.8	8.0	1.9	2.8
Forced expiratory volume in 1-second (FEV1), predicted	3.0	6.3	12.5	-0.2	3.5
Medication: Lansoprazole	2.9	3.3	4.7	-1.4	-2.2
Illnesses of mother	2.9	3.6	4.3	-2.1	-1.7
Impedance of arm (left)	2.8	12.7	22.2	-4.7	-1.8
Qualifications: O levels/GCSEs or equivalent	2.8	4.5	4.8	-2.1	-2.2
Medication: Omeprazole	2.8	3.3	3.9	-1.7	-2.0
Type 2 Diabetes (T2D) (2012)	2.7	3.1	5.3	2.3	1.0
Chronotype (morning person)	2.7	6.3	10.1	1.6	3.2
Medication: Amlodipine	2.6	3.7	5.2	2.3	1.5
Ever unenthusiastic/disinterested for a whole week	2.5	3.0	5.8	-0.4	-2.4
Medication: Ramipril	2.4	3.1	5.1	1.0	2.3
Qualifications: nursing, teaching	2.4	3.7	5.2	-2.3	-1.5
Back pain experienced in last month	2.4	3.4	4.3	1.6	2.1
Vitamin and mineral supplements	2.3	3.1	4.0	1.5	2.0
High blood pressure (siblings)	2.3	3.3	4.8	2.2	1.3
Medication: Ibuprofen	2.3	2.7	3.2	1.5	1.8
Medication: Gliclazide	2.3	2.6	5.1	-0.5	2.2
Angina	2.2	2.8	4.9	2.2	0.9
Pulse wave peak to peak time	2.2	2.5	2.6	1.6	1.6
Age started oral contraceptive pill	2.2	2.7	3.6	-1.9	-1.4
Impedance of whole body	2.2	11.4	20.1	-4.5	-1.6
Fasting Glucose	2.0	2.4	3.4	1.8	1.2
Systolic blood pressure, automated reading	2.0	5.9	9.4	3.1	1.6
Heart attack	2.0	2.6	5.1	2.3	-0.2
Pain all over the body in last month	2.0	2.2	2.3	-1.4	-1.5
Medication: Simvastatin	2.0	3.0	5.5	0.7	2.3
Heart attack/myocardial infarction (self-reported)	2.0	2.6	5.2	2.3	-0.2
Neuroticism (2016)	1.9	2.7	5.4	2.3	0.2
Fed-up feelings	1.9	3.4	5.8	2.4	1.0
Lung cancer (father)	1.9	2.2	2.2	1.5	1.5
Pulse wave Arterial Stiffness index	1.9	2.2	2.9	-1.7	-1.2
LDL Cholesterol	1.8	2.9	3.2	1.8	1.6
Average weekly spirits intake	1.8	2.2	3.2	-1.1	-1.8
Multivitamins +/- minerals	1.8	2.3	3.5	-1.0	-1.9
Worrier / anxious feelings	1.8	3.3	6.1	2.5	-0.7
Medication: Ventolin 100micrograms inhaler	1.8	2.3	4.3	-0.6	-2.1
Angina (self-reported)	1.8	2.4	3.6	1.9	1.1
Type 2 Diabetes (T2D) (2018)	1.7	3.2	4.8	1.3	2.2
Hearing difficulty/problems with background noise	1.7	2.7	3.3	1.8	1.4
Stomach or abdominal pain in last month	1.6	2.0	3.9	-0.4	-2.0
Medication: Allopurinol	1.6	2.2	2.8	-1.7	-1.2
Diabetes diagnosed by doctor	1.6	2.6	5.1	0.5	2.2
Medication: Aspirin	1.6	2.0	3.1	1.8	1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.6	3.4	6.1	-0.8	-2.5
Hypothyroidism (self reported)	1.5	3.4	4.7	2.2	1.4
Supplements: Glucosamine	1.5	1.9	3.3	-1.8	-0.7
Time employed in main current job	1.5	1.7	3.1	0.6	1.8
Chest pain or discomfort	1.5	2.1	4.2	2.0	0.1
Diabetes (self-reported)	1.4	2.2	3.6	0.9	1.9
Number of full brothers	1.4	1.8	3.4	0.4	1.8
Arm predicted mass (right)	1.4	7.2	8.0	2.8	2.5
Suffer from ‘nerves’	1.4	2.1	3.7	1.9	0.8
HDL Cholesterol	1.3	2.1	2.6	-1.3	-1.6
Blood Platelet Count	1.3	15.4	28.0	-5.3	-1.7
Relative age of first facial hair	1.3	2.6	4.8	-0.6	2.2
Falls in the last year	1.3	1.8	2.1	1.2	1.5
Arm fat-free mass (right)	1.3	6.6	8.0	2.8	2.3
Age at last live birth	1.3	1.9	3.5	-1.9	-0.6
Ovarian Cancer	1.2	1.6	2.7	1.6	0.7
Neuroticism	1.2	2.8	4.5	2.1	1.1
Neuroticism score	1.2	2.5	4.4	2.1	0.8
Frequency of tiredness / lethargy in last 2 weeks	1.2	2.0	3.6	0.6	1.9
Noisy workplace	1.2	1.5	2.4	1.6	0.7
Commuting to job workplace: Car/motor vehicle	1.2	1.3	2.2	-1.5	-0.7
Guilty feelings	1.2	1.8	2.2	1.5	1.2
Number of operations (self-reported)	1.2	1.8	3.6	-0.1	-1.9
Alzheimer’s Disease (in father)	1.1	1.2	2.3	-1.5	0.2
Bipolar Disorder (2011)	1.1	1.1	1.3	0.9	-1.2
Primary Biliary Cirrhosis	1.1	1.5	2.5	0.7	-1.6
Sensitivity / hurt feelings	1.1	1.9	3.5	1.9	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.4	2.4	0.6	-1.6
Serious illness, injury or assault to yourself	1.1	1.4	2.1	-0.8	-1.4
Exposure to tobacco smoke at home	1.1	1.2	2.0	1.4	0.7
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	2.5	-1.6	-0.4
Illness, injury, bereavement, stress in last 2 years	1.1	1.4	2.0	-0.8	-1.4
Illnesses of siblings: Diabetes	1.1	1.3	1.9	1.4	0.9
Mood swings	1.1	2.0	3.9	2.0	-0.2
Supplements: Calcium	1.1	1.2	1.7	1.3	-0.9
Allergy or Eczema	1.0	2.7	4.8	-2.2	-0.8
Ever used hormone-replacement therapy (HRT)	1.0	1.2	1.8	-0.8	-1.3
Average weekly fortified wine intake	1.0	1.2	2.3	-1.5	0.3
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	1.3	-1.0	1.1
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.2	4.3	-0.2	2.1
Allergy	1.0	2.3	3.1	1.2	1.8
Trunk fat-free mass	1.0	5.5	5.9	2.4	2.3
Hair/balding pattern: Pattern 3	1.0	1.5	1.9	1.0	-1.4
Number of live births	1.0	1.4	1.9	1.4	1.0
Neck or shoulder pain in last month	1.0	1.5	2.1	0.9	1.4
Had major operations	1.0	1.1	1.3	-1.1	-1.0
Arm fat-free mass (left)	1.0	5.0	6.2	2.5	1.9
Irritable Bowel Disease (IBD)	0.9	2.1	3.4	-0.9	-1.9
Coronary Artery Disease (CAD)	0.9	1.0	1.8	0.5	1.4
Ever had hysterectomy (womb removed)	0.9	1.0	1.8	0.4	-1.4
Diabetes (father)	0.9	1.1	1.5	0.9	1.2
Taking other prescription medications	0.9	1.4	2.4	-0.6	-1.5
Medication: Levothyroxine sodium	0.9	1.4	2.9	1.7	-0.1
Impedance of leg (left)	0.9	4.4	8.6	-2.9	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	2.8	1.7	-0.3
Illnesses of siblings	0.9	1.3	2.3	-1.5	-0.5
Medication: Cholesterol lowering	0.9	1.4	2.8	1.7	0.3
Trunk predicted mass	0.9	5.0	5.2	2.3	2.2
Hypothyroidism/myxoedema (self-reported)	0.9	1.7	3.4	1.8	0.0
Wheeze or whistling in the chest in last year	0.9	1.5	2.6	-0.7	-1.6
Knee pain experienced in last month	0.9	1.4	2.8	-0.2	1.7
Whole body fat-free mass	0.9	5.2	6.0	2.4	2.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.0	2.0	-1.4	-0.2
Whole body water mass	0.9	5.2	6.2	2.5	2.1
Supplements: Fish oil (including cod liver oil)	0.9	1.2	1.5	1.0	-1.2
Medication: Lisinopril	0.9	1.2	1.9	1.4	0.7
Arm predicted mass (left)	0.9	4.6	5.9	2.4	1.8
Bipolar Disorder or Schizophrenia	0.8	2.0	2.1	1.4	1.4
Schizophrenia vs Biploar Disorder	0.8	1.0	1.4	-1.2	-0.7
Alzheimer’s Disease (including proxy)	0.8	1.2	2.3	-1.5	0.1
Medication for hormone replacement therapy	0.8	0.9	0.9	0.9	-1.0
Impedance of leg (right)	0.8	3.8	7.6	-2.8	-0.1
Fluid intelligence score	0.8	1.6	2.9	-0.6	-1.7
Hip circumference	0.8	3.5	4.4	2.1	1.6
Father’s age at death	0.8	1.1	1.3	-0.9	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	2.2	0.4	-1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	1.1	1.1	0.9
Pulse rate, automated reading	0.8	2.4	3.1	-1.3	1.8
Smoking status: Previous	0.8	1.2	2.1	0.6	1.5
Ever taken oral contraceptive pill	0.8	0.9	1.1	-1.1	-0.8
Basal metabolic rate	0.8	4.2	4.9	2.2	1.9
Basal cell carcinoma (self-reported)	0.8	0.9	1.6	0.5	1.3
Depressed Affect (Nagel 2018)	0.7	1.5	2.9	1.7	-0.2
Depression (Nagel 2018)	0.7	1.1	2.2	-0.1	-1.5
Ulcerative Colitis (UC)	0.7	1.3	1.5	-1.1	-1.2
Verbal and Numeric Reasoning (VNR)	0.7	1.6	2.2	-1.0	-1.5
Breast Cancer	0.7	1.6	3.1	-0.1	-1.8
Lung FVC	0.7	3.5	6.3	0.9	-2.5
Medication: Metformin	0.7	0.9	1.6	-0.5	1.3
Severe depression (siblings)	0.7	0.8	1.2	-1.1	0.6
Leg fat-free mass (left)	0.7	3.9	4.5	2.1	1.8
Leg predicted mass (left)	0.7	3.6	4.0	2.0	1.8
Qualifications: None of the above	0.7	1.6	1.6	1.3	1.2
Pulse rate	0.7	1.2	1.3	-1.1	1.1
Qualifications: A levels/AS levels or equivalent	0.7	1.5	2.2	-1.5	-0.9
Peak expiratory flow (PEF)	0.7	1.7	3.0	-1.7	-0.6
Medication: Paracetamol	0.7	1.1	2.2	1.5	-0.1
Exposure to tobacco smoke outside home	0.7	1.0	1.7	0.5	-1.3
Ever had bowel cancer screening	0.7	0.8	0.9	-1.0	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	1.5	1.2	-0.1
Commuting to job workplace: Public transport	0.7	0.9	1.6	0.4	-1.2
Pain type(s) experienced in last month: Hip pain	0.7	0.8	1.1	-1.0	-0.8
Neuroticism (Nagel 2018)	0.6	1.5	2.7	1.6	-0.6
Reaction Time	0.6	1.2	2.3	1.5	0.1
Rheumatoid Arthritis	0.6	0.8	1.5	-1.2	-0.1
Alcohol intake versus 10 years previously	0.6	0.9	1.2	1.1	0.7
Happiness	0.6	0.7	1.4	-0.1	-1.2
Tense / ‘highly strung’	0.6	1.0	1.1	1.1	0.9
Headache pain in last month	0.6	1.1	2.0	-0.4	-1.4
Medication: Seretide 50 evohaler	0.6	0.7	1.2	-0.5	-1.1
Overall health rating	0.6	1.3	2.0	1.4	-0.7
Medication for cholesterol	0.6	0.9	1.0	-1.0	-0.9
Breast cancer (self-reported)	0.6	0.7	0.8	0.7	-0.9
Osteoporosis (self-reported)	0.6	0.7	1.0	0.7	-1.0
Hearing aid user	0.6	0.6	1.0	1.0	-0.5
Eye problems/disorders: Glaucoma	0.6	0.7	1.3	1.1	0.2
Medication: Atorvastatin	0.6	0.7	1.4	1.2	0.0
Alcohol drinker status: Never	0.6	0.7	1.1	0.6	1.0
Risk taking	0.6	0.8	1.5	-1.2	-0.4
Myopia	0.6	0.9	1.4	0.6	1.2
Bipolar Disorder (2018)	0.5	0.9	0.9	0.9	1.0
Schizophrenia (2018)	0.5	1.1	1.3	1.1	1.0
Worry (Nagel 2018)	0.5	1.1	2.1	1.4	0.4
HbA1C	0.5	0.6	1.1	-1.1	-0.1
Medication: Co-codamol	0.5	0.5	1.0	-1.0	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	2.2	0.1	1.5
Hair/balding pattern: Pattern 2	0.5	0.7	1.2	-1.1	-0.4
Hair/balding pattern: Pattern 4	0.5	1.2	1.9	-1.4	0.6
Ever highly irritable/argumentative for 2 days	0.5	0.6	0.7	0.7	-0.9
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	0.8	-0.9	0.8
Chronic bronchitis/emphysema (mother)	0.5	0.6	1.0	0.3	-1.0
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.2	-1.1	0.0
Emphysema/chronic bronchitis	0.5	0.6	1.1	1.1	0.1
Migraine (self-reported)	0.5	0.6	1.2	0.0	-1.1
Medication: Aspirin	0.5	0.7	1.0	1.0	0.7
Supplements: Vitamin C	0.5	0.6	0.9	-0.4	-1.0
Leg fat-free mass (right)	0.5	2.7	3.2	1.8	1.5
Commuting to job workplace: Walk	0.5	0.5	0.7	-0.6	0.8
Asthma (self-reported)	0.5	1.0	1.8	-0.5	-1.3
Leg predicted mass (right)	0.5	2.7	3.1	1.8	1.5
Miserableness	0.5	0.9	1.7	1.3	0.3
Fractured/broken bones in last 5 years	0.5	0.6	1.2	-1.1	-0.0
Heart disease (siblings)	0.5	0.6	0.7	-0.8	-0.8
Crohns Disease (2017)	0.4	1.0	1.5	-0.7	-1.2
BMI	0.4	2.3	4.3	2.1	-0.6
Frequency of depressed mood in last 2 weeks	0.4	0.5	0.8	0.9	-0.5
Supplements: Zinc	0.4	0.4	0.8	0.9	0.1
Pack years adult smoking proportion	0.4	0.6	0.7	0.7	0.8
Maternal smoking around birth	0.4	0.5	1.1	-0.1	1.0
Relative age voice broke	0.4	0.6	1.0	-0.5	1.0
Hayfever, allergic rhinitis or eczema	0.4	0.8	1.5	-1.2	-0.3
Body mass index (BMI)	0.4	1.6	3.2	1.8	0.1
Number of incorrect matches in round	0.4	0.7	1.4	0.2	-1.2
Financial difficulties in last 2 years	0.4	0.5	0.9	1.0	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	0.9	1.0	0.2
Asthma	0.4	0.7	1.4	-0.3	-1.2
Pulse wave reflection index	0.4	0.5	0.9	-0.3	-0.9
Age at first live birth	0.4	0.8	0.9	-0.9	-0.8
Qualifications: College or University degree	0.4	1.3	2.2	-1.5	-0.7
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	1.4	0.3	1.2
Smoking status: Current	0.4	0.6	1.2	0.1	-1.1
Average weekly champagne plus white wine intake	0.4	0.6	1.1	-1.1	0.3
Medication: Paracetamol	0.4	0.7	1.0	1.0	0.6
Pain experienced in last month	0.4	0.6	1.2	1.1	0.3
Alcohol drinker status: Previous	0.4	0.5	0.9	-0.9	0.3
Pack years of smoking	0.4	0.5	0.9	0.5	0.9
Ulcerative Colitis	0.3	0.5	1.0	-0.2	-1.0
Blood Red Count	0.3	3.1	5.9	0.6	-2.4
Lung FEV1/FVC ratio	0.3	1.6	3.1	1.8	-0.1
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.5	0.7	-0.5
Diabetes (mother)	0.3	0.4	0.6	0.8	-0.4
Trunk fat percentage	0.3	1.2	1.5	-1.2	-0.9
Current tobacco smoking	0.3	0.4	0.8	0.1	-0.9
Age when periods started (menarche)	0.3	0.8	1.4	-0.4	-1.2
Sitting height	0.3	1.9	3.8	-0.2	2.0
Length of working week for main job	0.3	0.3	0.6	0.8	-0.2
Glaucoma (self-reported)	0.3	0.4	0.5	0.6	0.7
Health satisfaction	0.3	0.5	0.7	0.8	0.5
Eye problems/disorders: None of the above	0.3	0.4	0.7	0.8	0.1
Family relationship satisfaction	0.3	0.4	0.8	-0.1	0.9
Leg pain on walking	0.3	0.3	0.5	-0.4	0.7
Friendships satisfaction	0.3	0.3	0.5	0.7	0.4
Wears glasses or contact lenses	0.3	0.4	0.6	0.3	0.8
Financial situation satisfaction	0.3	0.3	0.7	0.8	-0.1
Cholesterol lowering medication	0.3	0.4	0.4	-0.7	0.6
Intelligence (Savage-Jansen 2018)	0.2	0.7	1.1	-0.6	-1.0
Alzheimer’s Disease (in mother)	0.2	0.3	0.6	0.0	0.8
Mean Putamen Volume	0.2	0.3	0.5	0.7	0.2
Number of treatments/medications taken	0.2	0.3	0.4	0.6	0.4
Hearing difficulty/problems: Yes	0.2	0.3	0.4	0.7	0.3
Hand grip strength (right)	0.2	0.5	0.7	-0.4	-0.9
Past tobacco smoking	0.2	0.3	0.5	-0.5	-0.7
Mouth/teeth dental problems	0.2	0.2	0.4	0.6	-0.3
Weight	0.2	1.2	1.8	1.4	0.7
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	1.3	-0.4	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	0.5	0.7	0.2
Standing height	0.2	2.0	2.9	-1.1	1.7
Gout (self-reported)	0.2	0.3	0.4	-0.6	-0.5
Worry too long after embarrassment	0.2	0.4	0.7	0.4	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.5	0.0	-0.7
Medication for pain relief, constipation, heartburn	0.2	0.3	0.5	-0.7	-0.5
Mean time to correctly identify matches	0.2	0.3	0.4	0.6	-0.4
Alcohol intake frequency.	0.2	0.6	0.6	0.8	0.7
Comparative height size at age 10	0.2	0.9	1.5	0.5	1.2
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.4	-0.6	0.1
Average weekly red wine intake	0.2	0.3	0.5	0.7	-0.0
Loneliness, isolation	0.2	0.2	0.4	0.0	-0.7
Long-standing illness, disability or infirmity	0.2	0.3	0.6	0.8	0.2
Illnesses of father: None of the above (group 1)	0.2	0.3	0.5	0.2	-0.7
High cholesterol (Self-reported)	0.2	0.3	0.6	-0.1	-0.7
Ever smoked	0.2	0.3	0.3	0.5	0.6
Irritability	0.2	0.3	0.5	0.7	0.3
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.4	-0.7	0.2
Diastolic blood pressure, automated reading	0.2	0.7	0.9	0.7	1.0
Ever depressed for a whole week	0.2	0.3	0.5	0.2	-0.7
Commuting to job workplace: Cycle	0.2	0.3	0.4	0.5	0.6
Schizophrenia (2014)	0.1	0.3	0.4	0.5	0.6
Triglycerides	0.1	0.1	0.2	0.5	-0.0
Height	0.1	1.4	2.8	-0.3	1.7
Respiratory disease	0.1	0.3	0.3	-0.5	-0.6
Hand grip strength (left)	0.1	0.2	0.3	0.2	-0.6
Townsend deprivation index at recruitment	0.1	0.2	0.2	0.5	0.3
Waist circumference	0.1	0.2	0.3	-0.4	-0.5
Alcohol usually taken with meals	0.1	0.2	0.3	-0.5	-0.3
Nervous feelings	0.1	0.2	0.4	0.6	0.2
Had menopause	0.1	0.1	0.2	-0.1	-0.5
Had other major operations	0.1	0.2	0.3	0.2	-0.6
Forced vital capacity (FVC)	0.1	0.2	0.4	-0.1	0.6
Arm fat percentage (right)	0.1	0.2	0.4	0.1	-0.7
Mouth/teeth dental problems: Dentures	0.1	0.2	0.3	-0.5	-0.4
Depression (self-reported)	0.1	0.1	0.1	-0.2	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	0.4	0.3	0.6
Arm fat mass (right)	0.1	0.4	0.7	0.8	0.3
Loud music exposure frequency	0.1	0.1	0.2	0.4	-0.2
Body fat percentage	0.1	0.3	0.3	-0.5	-0.5
Leg fat percentage (right)	0.1	0.3	0.5	0.7	-0.4
Comparative body size at age 10	0.1	0.2	0.3	-0.6	-0.2
Number of children fathered	0.1	0.1	0.3	-0.1	0.5
Leg fat mass (right)	0.1	0.5	0.9	1.0	0.2
Number of full sisters	0.1	0.1	0.2	0.4	-0.0
Eye problems/disorders: Cataract	0.1	0.1	0.2	0.0	-0.5
Mineral and other dietary supplements	0.1	0.1	0.2	-0.2	0.4
Arm fat mass (left)	0.1	0.5	0.8	0.9	0.3
Mother’s age at death	0.1	0.1	0.2	-0.4	0.0
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.1	0.2	-0.4
Leg fat percentage (left)	0.1	0.4	0.6	0.8	-0.4
Unable to work because of sickness or disability	0.1	0.2	0.3	-0.5	0.1
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.2	0.5	0.2
Leg fat mass (left)	0.1	0.6	1.0	1.0	0.3
Major Depression (MDD)	0.0	0.0	0.0	-0.2	0.2
Crohns Disease (2012)	0.0	0.0	0.0	-0.1	0.1
Lupus	0.0	0.0	0.1	0.3	0.0
Blood Eosinophil Count	0.0	0.0	0.0	-0.2	0.0
Blood White Count	0.0	0.4	0.6	-0.3	0.8
Heel T-Score	0.0	0.2	0.3	-0.6	-0.3
Smoking Status	0.0	0.1	0.2	-0.1	-0.4
Hair Pigment	0.0	1.1	1.7	-1.3	0.7
Tanning	0.0	0.4	0.8	-0.2	-0.9
Eye problems/disorders: Diabetes related eye disease	0.0	0.0	0.0	-0.0	0.1
Trunk fat mass	0.0	0.1	0.1	-0.3	-0.2
Prospective memory result	0.0	0.0	0.0	-0.2	0.2
Blood clot in the leg (DVT)	0.0	0.0	0.1	0.2	-0.1
Forced vital capacity (FVC), Best measure	0.0	0.2	0.2	0.5	0.3
Heart disease (mother)	0.0	0.0	0.0	-0.2	0.0
Whole body fat mass	0.0	0.0	0.0	0.1	0.1
Illnesses of father: Heart disease	0.0	0.0	0.0	-0.2	0.1
Arm fat percentage (left)	0.0	0.1	0.2	0.2	-0.4
Number of self-reported non-cancer illnesses	0.0	0.1	0.1	0.3	-0.2

Hub : Genes

WIT1

Models

Trait associations