TWAS hub - ZFPM2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Colon Transverse	0.197	0.073	0.00580	-0.006	NA	0.010	NA	-0.006	0.97	NA	0.1000	NA	0.82000
2	TCGA	Thyroid Carcinoma	0.122	0.040	0.00014	0.002	0.054	0.026	NA	0.032	0.21	5.9e-06	0.0013	NA	0.00042

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Number of full sisters	6.2	7.6	10.5	3.2	2.2
Number of full brothers	5.9	7.4	7.5	2.7	2.7
Serious illness, injury or assault of a close relative in last 2 years	5.2	6.0	9.4	1.6	3.1
Medication: Atenolol	4.5	5.6	9.5	-3.1	-1.3
Heart disease (siblings)	4.4	5.4	8.6	-1.4	2.9
Osteoporosis (self-reported)	4.1	5.1	9.8	0.6	3.1
Ever depressed for a whole week	3.9	4.8	5.8	1.9	2.4
Health satisfaction	3.8	4.9	7.7	-1.4	2.8
Blood Platelet Count	3.7	43.3	83.7	9.2	1.7
Average weekly spirits intake	3.7	4.5	5.9	-2.4	-1.8
Ever unenthusiastic/disinterested for a whole week	3.6	4.4	5.4	1.8	2.3
Pulse wave reflection index	3.5	4.3	7.0	-2.7	-1.2
Neuroticism (2016)	3.4	4.9	8.4	1.2	2.9
Severe depression (siblings)	3.3	3.7	7.2	0.3	2.7
Frequency of unenthusiasm / disinterest in last 2 weeks	3.2	4.3	7.8	0.8	2.8
Body Mass Index (BMI) (2010)	3.1	4.3	4.4	-2.1	-2.0
Depression (self-reported)	2.7	3.2	3.9	1.6	2.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.7	5.8	11.6	3.4	0.1
Fractured/broken bones in last 5 years	2.7	3.5	5.9	-2.4	1.1
Depression (Nagel 2018)	2.6	3.9	6.2	1.3	2.5
Average weekly fortified wine intake	2.6	3.1	6.1	-2.5	0.3
Frequency of tiredness / lethargy in last 2 weeks	2.6	4.3	8.5	0.0	2.9
Tinnitus: Yes, but not now, but have in the past	2.3	2.5	3.9	2.0	1.1
Chronic bronchitis/emphysema (father)	2.2	2.5	3.8	-2.0	1.1
Illness, injury, bereavement, stress in last 2 years	2.2	2.6	5.2	-0.2	-2.3
Frequency of tenseness / restlessness in last 2 weeks	2.1	3.2	4.9	1.2	2.2
Eye problems/disorders: None of the above	2.1	2.5	4.3	-2.1	0.8
Eye problems/disorders: Cataract	2.1	2.4	4.5	2.1	-0.5
Smoking status: Current	1.9	3.0	5.9	-2.4	-0.3
Medication: Lisinopril	1.9	2.4	4.6	-2.1	-0.4
Age at First Birth	1.8	2.7	3.2	1.5	1.8
Chronotype (morning person)	1.8	4.2	5.9	1.6	-2.4
Hand grip strength (left)	1.8	4.8	9.3	0.5	-3.1
Alcohol usually taken with meals	1.8	2.9	4.1	-1.3	-2.0
Alcohol intake frequency.	1.8	4.2	7.0	2.7	-1.1
Schizophrenia (2018)	1.7	3.6	3.7	1.8	1.9
Prostate Cancer	1.7	2.4	4.1	-2.0	0.8
Townsend deprivation index at recruitment	1.7	2.4	4.8	0.1	2.2
Reason for reducing amount of alcohol drunk: Health precaution	1.7	2.0	4.0	2.0	-0.2
Commuting to job workplace: Public transport	1.7	2.0	2.9	1.7	1.1
Myopia	1.7	2.5	4.8	0.5	2.2
Frequency of depressed mood in last 2 weeks	1.6	2.2	3.3	1.1	1.8
Prospective memory result	1.6	1.9	2.2	1.3	1.5
Medication: Blood pressure	1.6	2.7	3.1	-1.5	-1.8
Diabetes (mother)	1.5	1.9	3.9	2.0	-0.0
Medication: Ramipril	1.5	2.0	2.5	-1.6	-1.2
Exposure to tobacco smoke outside home	1.5	2.0	2.1	1.5	1.4
Migraine (self-reported)	1.5	1.9	2.7	1.6	-1.0
Coronary Artery Disease (CAD)	1.4	1.7	2.4	-1.6	1.0
Current tobacco smoking	1.4	2.3	4.7	-2.2	0.1
Bilateral oophorectomy (both ovaries removed)	1.4	1.6	3.2	0.3	1.8
Serious illness, injury or assault to yourself	1.4	1.7	1.7	-1.3	1.3
Father’s age at death	1.4	1.9	3.5	1.9	-0.5
Forced expiratory volume in 1-second (FEV1)	1.4	4.7	6.4	2.5	-1.7
Mouth/teeth dental problems: Bleeding gums	1.4	1.8	3.2	-0.6	1.8
Blood clot in the leg (DVT)	1.4	1.8	3.6	1.9	0.1
Wheeze or whistling in the chest in last year	1.4	2.5	4.0	-2.0	1.0
Medication: Seretide 50 evohaler	1.4	1.6	3.1	0.3	1.8
Diabetes diagnosed by doctor	1.4	2.3	3.3	-1.8	-1.1
Deep venous thrombosis (DVT) (self-reported)	1.4	1.9	3.7	1.9	0.1
Verbal and Numeric Reasoning (VNR)	1.3	3.2	3.5	-1.9	-1.7
Angina (self-reported)	1.3	1.6	3.3	-1.8	0.1
Long-standing illness, disability or infirmity	1.3	2.1	3.5	-1.9	-0.8
Pain experienced in last month	1.3	2.2	3.1	1.8	1.1
Heart attack/myocardial infarction (self-reported)	1.3	1.6	2.7	-1.6	-0.8
Bipolar Disorder or Schizophrenia	1.2	3.0	4.1	1.3	2.0
Blood Red Count	1.2	11.3	21.4	4.6	-1.1
Angina	1.2	1.5	3.0	-1.7	0.2
Vitamin and mineral supplements	1.2	1.7	3.3	0.1	-1.8
Hearing difficulty/problems with background noise	1.2	1.9	1.9	1.4	1.4
Allergy	1.2	2.7	5.0	-0.6	-2.2
Mouth/teeth dental problems: Dentures	1.2	1.9	3.5	1.9	0.7
Chronic bronchitis/emphysema (mother)	1.2	1.4	2.7	-0.4	1.6
Medication: Allopurinol	1.2	1.6	2.9	-1.7	-0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	1.7	-1.1	1.3
Medication: Aspirin	1.2	1.6	1.8	-1.2	-1.4
Leg fat percentage (left)	1.2	4.4	8.3	0.7	-2.9
Triglycerides	1.1	1.7	3.3	-0.4	-1.8
Relative age of first facial hair	1.1	2.3	4.3	2.1	-0.5
Mouth/teeth dental problems	1.1	1.7	3.0	-0.6	-1.7
Hayfever/allergic rhinitis (self-reported)	1.1	1.4	2.7	0.4	1.6
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	2.0	1.4	1.3
Medication: Ventolin 100micrograms inhaler	1.1	1.5	2.1	-0.9	-1.4
Medication: Omeprazole	1.1	1.3	2.5	1.6	-0.2
Chest pain or discomfort	1.1	1.5	1.9	-1.4	1.1
Vascular/heart problems diagnosed by doctor	1.1	3.1	3.9	1.5	2.0
Basal cell carcinoma (self-reported)	1.1	1.3	1.5	1.2	1.0
Alzheimer’s Disease (in father)	1.0	1.1	1.3	1.0	-1.1
HDL Cholesterol	1.0	1.6	2.2	-1.5	1.0
Type 2 Diabetes (T2D) (2012)	1.0	1.2	1.2	-1.1	1.1
Lung FVC	1.0	4.8	9.1	3.0	-0.7
Hand grip strength (right)	1.0	2.6	5.2	-0.1	-2.3
Alcohol intake versus 10 years previously	1.0	1.4	2.0	1.4	-0.9
Hair/balding pattern: Pattern 3	1.0	1.5	1.6	-1.2	-1.2
Loud music exposure frequency	1.0	1.1	2.2	0.3	1.5
Leg fat percentage (right)	1.0	3.7	6.6	0.9	-2.6
Overall health rating	1.0	2.1	3.9	-0.6	2.0
Wears glasses or contact lenses	1.0	1.1	2.3	1.5	-0.2
Supplements: Fish oil (including cod liver oil)	1.0	1.3	1.6	0.9	1.3
Ulcerative Colitis (UC)	0.9	1.7	3.3	0.1	1.8
Schizophrenia (2014)	0.9	2.0	2.0	1.4	1.4
Smoking Status	0.9	2.2	2.5	-1.4	-1.6
Relative age voice broke	0.9	1.4	2.7	1.6	0.0
High blood pressure	0.9	2.6	3.7	-1.2	-1.9
Multivitamins +/- minerals	0.9	1.1	2.2	-0.1	1.5
Heart attack	0.9	1.2	1.9	-1.4	-0.6
Medication: Cholesterol lowering	0.9	1.3	2.1	-1.4	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	2.9	4.5	2.1	-1.1
Hypothyroidism/myxoedema (self-reported)	0.9	1.7	3.3	-1.8	-0.3
Medication: Ibuprofen	0.9	1.0	1.6	0.7	-1.2
Leg fat mass (right)	0.9	3.4	6.6	0.5	-2.6
Smoking status: Previous	0.9	1.3	2.0	0.8	-1.4
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	1.6	1.3	-0.6
Medication: Bendroflumethiazide	0.9	1.4	2.8	-1.7	-0.2
Cholesterol lowering medication	0.9	1.3	1.8	-0.9	1.3
Supplements: Calcium	0.9	1.0	2.1	-1.4	-0.0
Leg fat mass (left)	0.9	3.7	7.2	0.3	-2.7
Alzheimer’s Disease (in mother)	0.8	1.0	1.9	-1.4	0.1
Major Depression (MDD)	0.8	1.0	1.8	-0.4	1.3
Supplements: Zinc	0.8	0.8	1.4	-0.5	1.2
Qualifications: CSEs or equivalent	0.8	1.1	1.5	1.2	-0.8
Pulse rate	0.8	1.4	2.0	0.9	1.4
Asthma	0.8	1.5	2.7	-0.6	1.6
Emphysema/chronic bronchitis	0.8	0.9	1.7	0.4	1.3
Mean time to correctly identify matches	0.8	1.6	1.9	1.1	1.4
Arm predicted mass (right)	0.8	4.2	8.4	-0.2	-2.9
Average weekly beer plus cider intake	0.8	1.1	2.3	-1.5	-0.0
Age started oral contraceptive pill	0.8	1.0	1.9	-0.3	1.4
Alcohol drinker status: Previous	0.8	0.9	1.5	1.2	-0.5
Crohns Disease (2012)	0.7	1.2	1.4	-1.0	-1.2
Ulcerative Colitis	0.7	1.1	2.1	-0.3	1.4
BMI	0.7	4.0	7.5	-0.7	-2.7
Ever had hysterectomy (womb removed)	0.7	0.8	1.6	-0.0	1.2
Medication: Co-codamol	0.7	0.8	0.8	-0.8	0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.6	1.9	1.4	-1.1
Medication: Levothyroxine sodium	0.7	1.1	2.2	-1.5	0.3
Trunk fat mass	0.7	2.8	5.7	-0.1	-2.4
Past tobacco smoking	0.7	1.3	2.6	-0.2	1.6
Forced vital capacity (FVC)	0.7	2.6	3.9	2.0	-1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.5	3.1	1.8	-0.0
Illnesses of siblings	0.7	1.0	1.4	1.2	-0.7
Impedance of arm (right)	0.7	3.3	6.5	-0.3	2.6
Peak expiratory flow (PEF)	0.7	1.7	3.0	0.6	-1.7
Ever highly irritable/argumentative for 2 days	0.7	0.8	0.9	-0.9	0.9
Body fat percentage	0.7	2.7	5.4	-0.1	-2.3
Arm fat-free mass (right)	0.7	3.6	7.2	0.2	-2.7
Whole body fat mass	0.7	3.0	6.0	-0.1	-2.4
Medication: Aspirin	0.7	0.9	1.4	-1.2	-0.7
Hypertension (Self-reported)	0.7	2.0	2.5	-1.3	-1.6
Average weekly champagne plus white wine intake	0.7	1.0	1.0	-1.0	-1.0
Medication: Blood pressure	0.7	1.3	1.3	-1.1	-1.1
Unable to work because of sickness or disability	0.7	1.0	1.5	0.7	1.2
Hypothyroidism (self reported)	0.6	1.4	2.8	-1.7	0.2
Type 2 Diabetes (T2D) (2018)	0.6	1.1	1.2	-1.1	-1.0
Hearing difficulty/problems: Yes	0.6	0.9	0.9	0.9	0.9
Ever used hormone-replacement therapy (HRT)	0.6	0.7	1.4	-0.4	1.2
Medication: Metformin	0.6	0.8	1.5	-0.4	-1.2
Diabetes (father)	0.6	0.7	1.2	1.1	0.5
Falls in the last year	0.6	0.8	1.2	-0.6	-1.1
Gout (self-reported)	0.6	0.8	1.5	-1.2	-0.1
Neck or shoulder pain in last month	0.6	0.9	1.6	-0.4	-1.2
Asthma (self-reported)	0.6	1.2	2.0	-0.6	1.4
Miserableness	0.6	1.1	2.1	0.3	1.4
Hearing aid user	0.6	0.6	1.3	-0.1	-1.1
Pain type(s) experienced in last month: Hip pain	0.6	0.7	1.3	-0.3	1.1
Medication: Atorvastatin	0.6	0.8	1.1	-0.7	-1.0
Arm fat-free mass (left)	0.6	2.9	5.8	0.1	-2.4
Arm predicted mass (left)	0.6	3.3	6.6	0.2	-2.6
Intelligence (Savage-Jansen 2018)	0.5	1.5	1.6	-1.3	-1.2
Blood White Count	0.5	3.7	6.1	1.2	2.5
Impedance of leg (right)	0.5	2.3	4.6	2.1	0.2
Trunk fat percentage	0.5	2.0	3.9	-0.2	-2.0
Stomach or abdominal pain in last month	0.5	0.6	1.1	-1.1	0.4
Body mass index (BMI)	0.5	2.1	4.2	-0.1	-2.1
Impedance of leg (left)	0.5	2.4	4.8	2.2	-0.3
Had menopause	0.5	0.6	0.9	-0.9	0.6
Diabetes (self-reported)	0.5	0.8	1.1	-1.1	-0.7
Fluid intelligence score	0.5	1.1	1.8	-0.6	-1.4
Weight	0.5	2.6	5.3	-0.0	-2.3
Time employed in main current job	0.5	0.5	1.0	-1.0	-0.2
Qualifications: A levels/AS levels or equivalent	0.5	1.1	1.5	-1.2	0.8
Illnesses of mother	0.5	0.7	0.7	0.8	-0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	1.5	0.4	1.2
Forced vital capacity (FVC), Best measure	0.5	1.7	2.6	1.6	-0.8
Age at first live birth	0.5	0.9	1.6	-0.4	1.3
Medication for pain relief, constipation, heartburn	0.5	0.8	1.3	0.5	1.2
Age at last live birth	0.5	0.8	1.3	0.5	1.1
Leg fat-free mass (right)	0.5	2.5	3.1	-1.4	-1.8
Loneliness, isolation	0.5	0.7	0.8	0.9	-0.8
Ever had bowel cancer screening	0.5	0.5	0.6	0.7	0.7
Friendships satisfaction	0.5	0.7	0.7	-0.8	0.8
Commuting to job workplace: Walk	0.5	0.6	1.1	1.1	0.1
Leg predicted mass (right)	0.5	2.6	3.2	-1.4	-1.8
Irritability	0.5	0.8	1.5	-0.2	1.2
Waist Hip Ratio (WHR)	0.4	1.9	2.6	1.6	1.1
Cardiovascular Disease	0.4	1.2	1.9	-0.7	-1.4
Respiratory disease	0.4	0.8	1.1	-1.1	0.7
Neuroticism	0.4	1.0	1.7	0.5	1.3
Tanning	0.4	4.7	8.7	-3.0	-0.8
Pack years adult smoking proportion	0.4	0.7	1.2	-1.1	0.4
Leg fat-free mass (left)	0.4	2.2	2.8	-1.2	-1.7
Age when periods started (menarche)	0.4	1.1	1.9	-1.4	-0.5
Supplements: Glucosamine	0.4	0.5	0.9	-0.2	-1.0
Leg predicted mass (left)	0.4	2.2	2.8	-1.3	-1.7
Medication: Simvastatin	0.4	0.6	0.9	-0.6	0.9
Number of live births	0.4	0.6	0.9	0.5	1.0
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	0.9	0.0	-1.0
Impedance of arm (left)	0.4	2.0	3.9	-0.3	2.0
Arm fat mass (right)	0.4	1.6	3.2	-0.0	-1.8
Pulse wave peak to peak time	0.4	0.5	0.6	0.8	-0.6
Family relationship satisfaction	0.4	0.5	0.9	0.9	0.3
Commuting to job workplace: Car/motor vehicle	0.4	0.5	0.8	-0.9	-0.5
Knee pain experienced in last month	0.4	0.7	1.3	-1.1	0.2
Mood swings	0.4	0.7	1.5	-0.1	1.2
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	1.3	0.0	1.2
Arm fat mass (left)	0.4	1.8	3.6	0.2	-1.9
Basal metabolic rate	0.4	2.2	4.4	-0.3	-2.1
Diastolic blood pressure, automated reading	0.4	1.1	2.2	0.2	-1.5
Crohns Disease (2017)	0.3	0.8	1.0	-0.7	-1.0
Bipolar Disorder (2011)	0.3	0.3	0.5	-0.7	0.1
Allergy or Eczema	0.3	0.8	0.8	0.9	0.9
Sensitivity / hurt feelings	0.3	0.5	0.9	-0.9	0.3
Maternal smoking around birth	0.3	0.5	1.0	-0.1	-1.0
Taking other prescription medications	0.3	0.4	0.7	-0.4	-0.8
Hayfever, allergic rhinitis or eczema	0.3	0.7	1.3	0.2	1.2
High blood pressure (mother)	0.3	0.4	0.7	0.9	0.3
Number of incorrect matches in round	0.3	0.5	0.8	-0.3	0.9
Hair/balding pattern: Pattern 2	0.3	0.4	0.6	0.8	0.5
Pulse wave Arterial Stiffness index	0.3	0.4	0.6	-0.8	0.4
Exposure to tobacco smoke at home	0.3	0.4	0.4	-0.6	-0.6
Worry too long after embarrassment	0.3	0.4	0.8	-0.9	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	0.8	-0.0	0.9
Supplements: Vitamin C	0.3	0.3	0.4	-0.6	0.5
Illnesses of siblings: Diabetes	0.3	0.3	0.4	0.5	0.6
Whole body fat-free mass	0.3	2.0	3.8	-0.4	-1.9
Arm fat percentage (left)	0.3	1.3	2.4	-0.4	-1.6
Handedness (chirality/laterality): Left-handed	0.3	0.4	0.7	0.8	0.2
Qualifications: nursing, teaching	0.3	0.5	1.1	1.0	-0.1
Back pain experienced in last month	0.3	0.5	0.8	0.3	-0.9
Illnesses of father: None of the above (group 1)	0.3	0.3	0.7	0.1	-0.8
Whole body water mass	0.3	1.9	3.7	-0.4	-1.9
Illnesses of father: High blood pressure	0.3	0.4	0.7	0.8	0.1
Risk taking	0.3	0.4	0.4	-0.6	0.6
Pack years of smoking	0.3	0.5	0.8	-0.9	0.3
Bipolar Disorder (2018)	0.2	0.4	0.8	-0.1	0.9
Alzheimer’s Disease (including proxy)	0.2	0.3	0.6	-0.8	-0.1
Reaction Time	0.2	0.4	0.6	0.8	-0.4
Breast Cancer	0.2	0.4	0.8	0.1	0.9
Ovarian Cancer	0.2	0.3	0.5	0.7	-0.3
Fasting Glucose	0.2	0.2	0.4	0.7	0.2
HbA1C	0.2	0.2	0.4	-0.6	-0.3
LDL Cholesterol	0.2	0.3	0.3	0.6	-0.6
Blood Eosinophil Count	0.2	1.7	2.5	1.6	0.9
Heel T-Score	0.2	1.9	2.0	1.4	-1.3
Systolic Blood Pressure	0.2	0.8	1.6	-1.3	-0.2
Number of treatments/medications taken	0.2	0.3	0.6	-0.1	0.8
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	0.2	0.4	0.5
Eye problems/disorders: Diabetes related eye disease	0.2	0.3	0.5	0.7	0.1
Medication for hormone replacement therapy	0.2	0.2	0.2	-0.4	-0.4
Financial difficulties in last 2 years	0.2	0.3	0.5	-0.7	0.3
Neuroticism score	0.2	0.4	0.8	0.0	0.9
Arm fat percentage (right)	0.2	0.9	1.6	-0.5	-1.3
Trunk fat-free mass	0.2	1.4	2.7	0.1	-1.6
Hip circumference	0.2	0.8	1.1	-0.8	-1.0
Worrier / anxious feelings	0.2	0.3	0.7	-0.8	0.1
Medication: Lansoprazole	0.2	0.2	0.4	0.2	0.7
Trunk predicted mass	0.2	1.4	2.7	0.1	-1.6
Length of working week for main job	0.2	0.3	0.5	-0.7	0.2
Birth weight of first child	0.2	0.3	0.4	0.5	-0.6
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.5	-0.7	0.3
Medication: Paracetamol	0.2	0.3	0.6	0.8	-0.0
Comparative body size at age 10	0.2	0.5	0.9	-0.3	-1.0
Shortness of breath walking on level ground	0.2	0.3	0.4	-0.3	0.7
Qualifications: College or University degree	0.2	0.5	1.1	-0.1	1.0
Heart disease (mother)	0.2	0.2	0.4	-0.3	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	0.6	-0.1	0.8
Pulse rate, automated reading	0.2	0.5	0.7	0.5	-0.8
Had major operations	0.2	0.2	0.3	0.3	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	0.7	0.9	0.2
Average weekly red wine intake	0.2	0.3	0.5	0.1	-0.7
Breast cancer (self-reported)	0.2	0.2	0.4	-0.6	0.2
Osteoarthritis (self-reported)	0.2	0.3	0.6	-0.8	-0.1
Medication: Gliclazide	0.2	0.2	0.4	0.2	-0.6
Number of self-reported non-cancer illnesses	0.2	0.3	0.5	-0.7	-0.2
Ever taken oral contraceptive pill	0.2	0.2	0.3	0.2	-0.6
Mother’s age at death	0.2	0.3	0.3	-0.6	0.5
High cholesterol (Self-reported)	0.2	0.4	0.5	-0.7	0.4
Medication: Paracetamol	0.2	0.3	0.6	0.8	0.2
Ever smoked	0.2	0.4	0.8	-0.1	-0.9
Worry (Nagel 2018)	0.1	0.1	0.1	0.4	-0.3
Irritable Bowel Disease (IBD)	0.1	0.3	0.6	0.1	0.8
Mean Putamen Volume	0.1	0.1	0.2	0.1	-0.5
Lupus	0.1	0.2	0.3	0.4	-0.5
Primary Biliary Cirrhosis	0.1	0.1	0.2	-0.0	0.4
Rheumatoid Arthritis	0.1	0.2	0.4	-0.1	-0.6
Lung FEV1/FVC ratio	0.1	0.6	0.6	0.8	-0.7
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.2	0.3	-0.4
Sitting height	0.1	1.0	2.0	-0.1	-1.4
Waist circumference	0.1	0.5	1.0	-0.2	-1.0
Qualifications: None of the above	0.1	0.2	0.2	0.4	0.4
Pain all over the body in last month	0.1	0.1	0.1	-0.4	-0.0
Happiness	0.1	0.1	0.2	0.3	0.4
Noisy workplace	0.1	0.1	0.3	0.5	-0.0
Lung cancer (father)	0.1	0.1	0.1	-0.3	-0.3
Breastfed as a baby	0.1	0.1	0.2	-0.5	0.2
Hair/balding pattern: Pattern 4	0.1	0.1	0.2	0.5	0.2
Headache pain in last month	0.1	0.2	0.4	-0.3	0.6
Birth weight	0.1	0.2	0.4	0.1	-0.7
Number of children fathered	0.1	0.1	0.1	0.3	0.1
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.2	-0.4	-0.2
Leg pain on walking	0.1	0.1	0.1	-0.3	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.2	0.5	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.2	0.3	0.2	-0.5
Illnesses of father: Heart disease	0.1	0.2	0.2	-0.5	0.4
Medication for cholesterol	0.1	0.1	0.2	0.4	-0.2
Mineral and other dietary supplements	0.1	0.2	0.4	-0.1	-0.6
Financial situation satisfaction	0.1	0.2	0.3	-0.3	0.5
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.1	0.3	0.4
Eye problems/disorders: Glaucoma	0.1	0.1	0.1	0.4	-0.2
Number of operations (self-reported)	0.1	0.2	0.4	0.1	0.6
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.1	-0.2	-0.3
Commuting to job workplace: Cycle	0.1	0.1	0.3	-0.5	0.1
Impedance of whole body	0.1	0.7	1.0	0.7	1.0
Depressed Affect (Nagel 2018)	0.0	0.1	0.1	0.3	-0.3
Neuroticism (Nagel 2018)	0.0	0.0	0.0	-0.1	-0.1
Schizophrenia vs Biploar Disorder	0.0	0.0	0.1	-0.2	0.1
Height	0.0	0.1	0.2	-0.4	0.2
Hair Pigment	0.0	1.3	2.2	0.5	-1.5
Systolic blood pressure, automated reading	0.0	0.0	0.1	0.2	0.2
Fed-up feelings	0.0	0.0	0.1	0.1	-0.3
Nervous feelings	0.0	0.1	0.1	0.2	-0.4
Had other major operations	0.0	0.0	0.1	-0.1	-0.3
Standing height	0.0	0.4	0.4	0.6	-0.7
Tense / ‘highly strung’	0.0	0.0	0.0	-0.1	0.2
Glaucoma (self-reported)	0.0	0.1	0.1	0.0	-0.3
Medication: Amlodipine	0.0	0.1	0.1	0.4	-0.1
High blood pressure (siblings)	0.0	0.0	0.1	0.2	-0.1
Comparative height size at age 10	0.0	0.1	0.2	0.0	-0.4
Suffer from ‘nerves’	0.0	0.1	0.1	0.3	-0.3
Guilty feelings	0.0	0.1	0.1	-0.3	0.2
Alcohol drinker status: Never	0.0	0.0	0.1	-0.3	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.0	0.0	0.0	0.2	0.1

Hub : Genes

ZFPM2

Models

Trait associations