Hub : Genes

ZFPM2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Colon Transverse 0.197 0.073 0.00580 -0.006 NA 0.010 NA -0.006 0.97 NA 0.1000 NA 0.82000
2 TCGA Thyroid Carcinoma 0.122 0.040 0.00014 0.002 0.054 0.026 NA 0.032 0.21 5.9e-06 0.0013 NA 0.00042

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.2 0.4 0.8 -0.1 0.9
Bipolar Disorder or Schizophrenia 1.2 3.0 4.1 1.3 2.0
Depressed Affect (Nagel 2018) 0.0 0.1 0.1 0.3 -0.3
Depression (Nagel 2018) 2.6 3.9 6.2 1.3 2.5
Intelligence (Savage-Jansen 2018) 0.5 1.5 1.6 -1.3 -1.2
Neuroticism (Nagel 2018) 0.0 0.0 0.0 -0.1 -0.1
Schizophrenia (2018) 1.7 3.6 3.7 1.8 1.9
Schizophrenia vs Biploar Disorder 0.0 0.0 0.1 -0.2 0.1
Worry (Nagel 2018) 0.1 0.1 0.1 0.4 -0.3
Alzheimer’s Disease (in mother) 0.8 1.0 1.9 -1.4 0.1
Alzheimer’s Disease (in father) 1.0 1.1 1.3 1.0 -1.1
Alzheimer’s Disease (including proxy) 0.2 0.3 0.6 -0.8 -0.1
Crohns Disease (2017) 0.3 0.8 1.0 -0.7 -1.0
Irritable Bowel Disease (IBD) 0.1 0.3 0.6 0.1 0.8
Ulcerative Colitis (UC) 0.9 1.7 3.3 0.1 1.8
Major Depression (MDD) 0.8 1.0 1.8 -0.4 1.3
Reaction Time 0.2 0.4 0.6 0.8 -0.4
Verbal and Numeric Reasoning (VNR) 1.3 3.2 3.5 -1.9 -1.7
Breast Cancer 0.2 0.4 0.8 0.1 0.9
Ovarian Cancer 0.2 0.3 0.5 0.7 -0.3
Prostate Cancer 1.7 2.4 4.1 -2.0 0.8
Age at First Birth 1.8 2.7 3.2 1.5 1.8
Bipolar Disorder (2011) 0.3 0.3 0.5 -0.7 0.1
Body Mass Index (BMI) (2010) 3.1 4.3 4.4 -2.1 -2.0
Coronary Artery Disease (CAD) 1.4 1.7 2.4 -1.6 1.0
Crohns Disease (2012) 0.7 1.2 1.4 -1.0 -1.2
Mean Putamen Volume 0.1 0.1 0.2 0.1 -0.5
Fasting Glucose 0.2 0.2 0.4 0.7 0.2
HbA1C 0.2 0.2 0.4 -0.6 -0.3
HDL Cholesterol 1.0 1.6 2.2 -1.5 1.0
LDL Cholesterol 0.2 0.3 0.3 0.6 -0.6
Lupus 0.1 0.2 0.3 0.4 -0.5
Neuroticism (2016) 3.4 4.9 8.4 1.2 2.9
Primary Biliary Cirrhosis 0.1 0.1 0.2 -0.0 0.4
Rheumatoid Arthritis 0.1 0.2 0.4 -0.1 -0.6
Schizophrenia (2014) 0.9 2.0 2.0 1.4 1.4
Triglycerides 1.1 1.7 3.3 -0.4 -1.8
Type 2 Diabetes (T2D) (2012) 1.0 1.2 1.2 -1.1 1.1
Ulcerative Colitis 0.7 1.1 2.1 -0.3 1.4
Blood Eosinophil Count 0.2 1.7 2.5 1.6 0.9
Blood Platelet Count 3.7 43.3 83.7 9.2 1.7
Blood Red Count 1.2 11.3 21.4 4.6 -1.1
Blood White Count 0.5 3.7 6.1 1.2 2.5
Heel T-Score 0.2 1.9 2.0 1.4 -1.3
BMI 0.7 4.0 7.5 -0.7 -2.7
Height 0.0 0.1 0.2 -0.4 0.2
Waist Hip Ratio (WHR) 0.4 1.9 2.6 1.6 1.1
Systolic Blood Pressure 0.2 0.8 1.6 -1.3 -0.2
Smoking Status 0.9 2.2 2.5 -1.4 -1.6
Allergy or Eczema 0.3 0.8 0.8 0.9 0.9
Cardiovascular Disease 0.4 1.2 1.9 -0.7 -1.4
Hypothyroidism (self reported) 0.6 1.4 2.8 -1.7 0.2
Respiratory disease 0.4 0.8 1.1 -1.1 0.7
Type 2 Diabetes (T2D) (2018) 0.6 1.1 1.2 -1.1 -1.0
Lung FEV1/FVC ratio 0.1 0.6 0.6 0.8 -0.7
Lung FVC 1.0 4.8 9.1 3.0 -0.7
Neuroticism 0.4 1.0 1.7 0.5 1.3
Chronotype (morning person) 1.8 4.2 5.9 1.6 -2.4
Hair Pigment 0.0 1.3 2.2 0.5 -1.5
Tanning 0.4 4.7 8.7 -3.0 -0.8
Hand grip strength (left) 1.8 4.8 9.3 0.5 -3.1
Number of treatments/medications taken 0.2 0.3 0.6 -0.1 0.8
Average weekly spirits intake 3.7 4.5 5.9 -2.4 -1.8
Sensitivity / hurt feelings 0.3 0.5 0.9 -0.9 0.3
Frequency of depressed mood in last 2 weeks 1.6 2.2 3.3 1.1 1.8
Hearing difficulty/problems: Yes 0.6 0.9 0.9 0.9 0.9
Relative age of first facial hair 1.1 2.3 4.3 2.1 -0.5
Other serious medical condition/disability diagnosed by doctor 0.2 0.2 0.2 0.4 0.5
Ever used hormone-replacement therapy (HRT) 0.6 0.7 1.4 -0.4 1.2
Ever had hysterectomy (womb removed) 0.7 0.8 1.6 -0.0 1.2
Systolic blood pressure, automated reading 0.0 0.0 0.1 0.2 0.2
Eye problems/disorders: Diabetes related eye disease 0.2 0.3 0.5 0.7 0.1
Angina 1.2 1.5 3.0 -1.7 0.2
Medication for hormone replacement therapy 0.2 0.2 0.2 -0.4 -0.4
Vitamin and mineral supplements 1.2 1.7 3.3 0.1 -1.8
Supplements: Zinc 0.8 0.8 1.4 -0.5 1.2
Medication: Co-codamol 0.7 0.8 0.8 -0.8 0.9
Medication: Metformin 0.6 0.8 1.5 -0.4 -1.2
Diabetes (father) 0.6 0.7 1.2 1.1 0.5
Diabetes (mother) 1.5 1.9 3.9 2.0 -0.0
Severe depression (siblings) 3.3 3.7 7.2 0.3 2.7
Pack years adult smoking proportion 0.4 0.7 1.2 -1.1 0.4
Impedance of leg (right) 0.5 2.3 4.6 2.1 0.2
Leg fat-free mass (left) 0.4 2.2 2.8 -1.2 -1.7
Trunk fat percentage 0.5 2.0 3.9 -0.2 -2.0
Hand grip strength (right) 1.0 2.6 5.2 -0.1 -2.3
Townsend deprivation index at recruitment 1.7 2.4 4.8 0.1 2.2
Current tobacco smoking 1.4 2.3 4.7 -2.2 0.1
Average weekly fortified wine intake 2.6 3.1 6.1 -2.5 0.3
Maternal smoking around birth 0.3 0.5 1.0 -0.1 -1.0
Fed-up feelings 0.0 0.0 0.1 0.1 -0.3
Frequency of unenthusiasm / disinterest in last 2 weeks 3.2 4.3 7.8 0.8 2.8
Relative age voice broke 0.9 1.4 2.7 1.6 0.0
Taking other prescription medications 0.3 0.4 0.7 -0.4 -0.8
Age when periods started (menarche) 0.4 1.1 1.9 -1.4 -0.5
Bilateral oophorectomy (both ovaries removed) 1.4 1.6 3.2 0.3 1.8
Heel bone mineral density (BMD) T-score, automated (left) 0.7 1.6 1.9 1.4 -1.1
Tinnitus: Yes, but not now, but have in the past 2.3 2.5 3.9 2.0 1.1
Qualifications: CSEs or equivalent 0.8 1.1 1.5 1.2 -0.8
Serious illness, injury or assault to yourself 1.4 1.7 1.7 -1.3 1.3
High blood pressure 0.9 2.6 3.7 -1.2 -1.9
Hayfever, allergic rhinitis or eczema 0.3 0.7 1.3 0.2 1.2
Multivitamins +/- minerals 0.9 1.1 2.2 -0.1 1.5
Stomach or abdominal pain in last month 0.5 0.6 1.1 -1.1 0.4
Supplements: Glucosamine 0.4 0.5 0.9 -0.2 -1.0
Diverticular disease/diverticulitis (self-reported) 0.1 0.1 0.2 0.3 -0.4
Medication: Atenolol 4.5 5.6 9.5 -3.1 -1.3
Medication: Levothyroxine sodium 0.7 1.1 2.2 -1.5 0.3
Sitting height 0.1 1.0 2.0 -0.1 -1.4
Chronic bronchitis/emphysema (father) 2.2 2.5 3.8 -2.0 1.1
High blood pressure (mother) 0.3 0.4 0.7 0.9 0.3
Body mass index (BMI) 0.5 2.1 4.2 -0.1 -2.1
Impedance of leg (left) 0.5 2.4 4.8 2.2 -0.3
Leg predicted mass (left) 0.4 2.2 2.8 -1.3 -1.7
Trunk fat mass 0.7 2.8 5.7 -0.1 -2.4
Waist circumference 0.1 0.5 1.0 -0.2 -1.0
Number of incorrect matches in round 0.3 0.5 0.8 -0.3 0.9
Past tobacco smoking 0.7 1.3 2.6 -0.2 1.6
Alcohol usually taken with meals 1.8 2.9 4.1 -1.3 -2.0
Nervous feelings 0.0 0.1 0.1 0.2 -0.4
Frequency of tenseness / restlessness in last 2 weeks 2.1 3.2 4.9 1.2 2.2
Hearing difficulty/problems with background noise 1.2 1.9 1.9 1.4 1.4
Hair/balding pattern: Pattern 2 0.3 0.4 0.6 0.8 0.5
Had menopause 0.5 0.6 0.9 -0.9 0.6
Had other major operations 0.0 0.0 0.1 -0.1 -0.3
Forced vital capacity (FVC) 0.7 2.6 3.9 2.0 -1.2
Heel bone mineral density (BMD) T-score, automated (right) 0.7 1.5 3.1 1.8 -0.0
Ever unenthusiastic/disinterested for a whole week 3.6 4.4 5.4 1.8 2.3
Qualifications: None of the above 0.1 0.2 0.2 0.4 0.4
Financial difficulties in last 2 years 0.2 0.3 0.5 -0.7 0.3
Mouth/teeth dental problems 1.1 1.7 3.0 -0.6 -1.7
Heart attack 0.9 1.2 1.9 -1.4 -0.6
Allergy 1.2 2.7 5.0 -0.6 -2.2
Pain all over the body in last month 0.1 0.1 0.1 -0.4 -0.0
Diabetes (self-reported) 0.5 0.8 1.1 -1.1 -0.7
Hayfever/allergic rhinitis (self-reported) 1.1 1.4 2.7 0.4 1.6
Medication: Ramipril 1.5 2.0 2.5 -1.6 -1.2
Medication: Simvastatin 0.4 0.6 0.9 -0.6 0.9
Fluid intelligence score 0.5 1.1 1.8 -0.6 -1.4
Illnesses of siblings 0.7 1.0 1.4 1.2 -0.7
Neuroticism score 0.2 0.4 0.8 0.0 0.9
Weight 0.5 2.6 5.3 -0.0 -2.3
Impedance of arm (right) 0.7 3.3 6.5 -0.3 2.6
Arm fat percentage (right) 0.2 0.9 1.6 -0.5 -1.3
Trunk fat-free mass 0.2 1.4 2.7 0.1 -1.6
Hip circumference 0.2 0.8 1.1 -0.8 -1.0
Time employed in main current job 0.5 0.5 1.0 -1.0 -0.2
Alcohol intake versus 10 years previously 1.0 1.4 2.0 1.4 -0.9
Father’s age at death 1.4 1.9 3.5 1.9 -0.5
Worrier / anxious feelings 0.2 0.3 0.7 -0.8 0.1
Frequency of tiredness / lethargy in last 2 weeks 2.6 4.3 8.5 0.0 2.9
Falls in the last year 0.6 0.8 1.2 -0.6 -1.1
Hair/balding pattern: Pattern 3 1.0 1.5 1.6 -1.2 -1.2
Number of live births 0.4 0.6 0.9 0.5 1.0
Forced expiratory volume in 1-second (FEV1) 1.4 4.7 6.4 2.5 -1.7
Pulse rate 0.8 1.4 2.0 0.9 1.4
Happiness 0.1 0.1 0.2 0.3 0.4
Noisy workplace 0.1 0.1 0.3 0.5 -0.0
Qualifications: A levels/AS levels or equivalent 0.5 1.1 1.5 -1.2 0.8
Serious illness, injury or assault of a close relative in last 2 years 5.2 6.0 9.4 1.6 3.1
Mouth/teeth dental problems: Dentures 1.2 1.9 3.5 1.9 0.7
Asthma 0.8 1.5 2.7 -0.6 1.6
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 0.9 0.0 -1.0
Medication: Cholesterol lowering 0.9 1.3 2.1 -1.4 -0.8
Depression (self-reported) 2.7 3.2 3.9 1.6 2.0
Medication: Lansoprazole 0.2 0.2 0.4 0.2 0.7
Prospective memory result 1.6 1.9 2.2 1.3 1.5
Lung cancer (father) 0.1 0.1 0.1 -0.3 -0.3
Illnesses of mother 0.5 0.7 0.7 0.8 -0.9
Forced expiratory volume in 1-second (FEV1), Best measure 0.9 2.9 4.5 2.1 -1.1
Pulse wave Arterial Stiffness index 0.3 0.4 0.6 -0.8 0.4
Impedance of arm (left) 0.4 2.0 3.9 -0.3 2.0
Arm fat mass (right) 0.4 1.6 3.2 -0.0 -1.8
Trunk predicted mass 0.2 1.4 2.7 0.1 -1.6
Standing height 0.0 0.4 0.4 0.6 -0.7
Length of working week for main job 0.2 0.3 0.5 -0.7 0.2
Exposure to tobacco smoke at home 0.3 0.4 0.4 -0.6 -0.6
Breastfed as a baby 0.1 0.1 0.2 -0.5 0.2
Tense / ‘highly strung’ 0.0 0.0 0.0 -0.1 0.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.5 0.8 1.5 0.4 1.2
Hair/balding pattern: Pattern 4 0.1 0.1 0.2 0.5 0.2
Birth weight of first child 0.2 0.3 0.4 0.5 -0.6
Peak expiratory flow (PEF) 0.7 1.7 3.0 0.6 -1.7
Pulse wave reflection index 3.5 4.3 7.0 -2.7 -1.2
Ever highly irritable/argumentative for 2 days 0.7 0.8 0.9 -0.9 0.9
Loud music exposure frequency 1.0 1.1 2.2 0.3 1.5
Qualifications: O levels/GCSEs or equivalent 0.2 0.3 0.5 -0.7 0.3
Mouth/teeth dental problems: Bleeding gums 1.4 1.8 3.2 -0.6 1.8
Blood clot in the leg (DVT) 1.4 1.8 3.6 1.9 0.1
Medication: Paracetamol 0.2 0.3 0.6 0.8 -0.0
Headache pain in last month 0.1 0.2 0.4 -0.3 0.6
Medication for cholesterol, blood pressure or diabetes 1.1 1.8 2.0 1.4 1.3
Glaucoma (self-reported) 0.0 0.1 0.1 0.0 -0.3
Gout (self-reported) 0.6 0.8 1.5 -1.2 -0.1
Hypothyroidism/myxoedema (self-reported) 0.9 1.7 3.3 -1.8 -0.3
Medication: Amlodipine 0.0 0.1 0.1 0.4 -0.1
Medication: Ventolin 100micrograms inhaler 1.1 1.5 2.1 -0.9 -1.4
Birth weight 0.1 0.2 0.4 0.1 -0.7
Chronic bronchitis/emphysema (mother) 1.2 1.4 2.7 -0.4 1.6
High blood pressure (siblings) 0.0 0.0 0.1 0.2 -0.1
Forced vital capacity (FVC), Best measure 0.5 1.7 2.6 1.6 -0.8
Body fat percentage 0.7 2.7 5.4 -0.1 -2.3
Leg fat percentage (right) 1.0 3.7 6.6 0.9 -2.6
Arm fat-free mass (right) 0.7 3.6 7.2 0.2 -2.7
Exposure to tobacco smoke outside home 1.5 2.0 2.1 1.5 1.4
Comparative body size at age 10 0.2 0.5 0.9 -0.3 -1.0
Number of full brothers 5.9 7.4 7.5 2.7 2.7
Worry too long after embarrassment 0.3 0.4 0.8 -0.9 -0.2
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.4 0.8 -0.0 0.9
Wheeze or whistling in the chest in last year 1.4 2.5 4.0 -2.0 1.0
Number of children fathered 0.1 0.1 0.1 0.3 0.1
Reason for reducing amount of alcohol drunk: Health precaution 1.7 2.0 4.0 2.0 -0.2
Age at first live birth 0.5 0.9 1.6 -0.4 1.3
Pulse wave peak to peak time 0.4 0.5 0.6 0.8 -0.6
Health satisfaction 3.8 4.9 7.7 -1.4 2.8
Shortness of breath walking on level ground 0.2 0.3 0.4 -0.3 0.7
Qualifications: College or University degree 0.2 0.5 1.1 -0.1 1.0
Eye problems/disorders: None of the above 2.1 2.5 4.3 -2.1 0.8
Mouth/teeth dental problems: Loose teeth 0.1 0.1 0.2 -0.4 -0.2
Emphysema/chronic bronchitis 0.8 0.9 1.7 0.4 1.3
Medication for pain relief, constipation, heartburn 0.5 0.8 1.3 0.5 1.2
Neck or shoulder pain in last month 0.6 0.9 1.6 -0.4 -1.2
Medication: Blood pressure 1.6 2.7 3.1 -1.5 -1.8
Angina (self-reported) 1.3 1.6 3.3 -1.8 0.1
Migraine (self-reported) 1.5 1.9 2.7 1.6 -1.0
Medication: Ibuprofen 0.9 1.0 1.6 0.7 -1.2
Medication: Allopurinol 1.2 1.6 2.9 -1.7 -0.5
Medication: Omeprazole 1.1 1.3 2.5 1.6 -0.2
Medication: Seretide 50 evohaler 1.4 1.6 3.1 0.3 1.8
Mean time to correctly identify matches 0.8 1.6 1.9 1.1 1.4
Heart disease (mother) 0.2 0.2 0.4 -0.3 0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.2 0.3 0.6 -0.1 0.8
Whole body fat mass 0.7 3.0 6.0 -0.1 -2.4
Leg fat mass (right) 0.9 3.4 6.6 0.5 -2.6
Arm predicted mass (right) 0.8 4.2 8.4 -0.2 -2.9
Pulse rate, automated reading 0.2 0.5 0.7 0.5 -0.8
Alcohol intake frequency. 1.8 4.2 7.0 2.7 -1.1
Comparative height size at age 10 0.0 0.1 0.2 0.0 -0.4
Number of full sisters 6.2 7.6 10.5 3.2 2.2
Suffer from ‘nerves’ 0.0 0.1 0.1 0.3 -0.3
Overall health rating 1.0 2.1 3.9 -0.6 2.0
Chest pain or discomfort 1.1 1.5 1.9 -1.4 1.1
Had major operations 0.2 0.2 0.3 0.3 -0.6
Age at last live birth 0.5 0.8 1.3 0.5 1.1
Family relationship satisfaction 0.4 0.5 0.9 0.9 0.3
Leg pain on walking 0.1 0.1 0.1 -0.3 0.3
Qualifications: NVQ or HND or HNC or equivalent 0.1 0.1 0.2 0.5 -0.3
Commuting to job workplace: Car/motor vehicle 0.4 0.5 0.8 -0.9 -0.5
Illness, injury, bereavement, stress in last 2 years 2.2 2.6 5.2 -0.2 -2.3
Medication: Aspirin 0.7 0.9 1.4 -1.2 -0.7
Supplements: Vitamin C 0.3 0.3 0.4 -0.6 0.5
Knee pain experienced in last month 0.4 0.7 1.3 -1.1 0.2
Hypertension (Self-reported) 0.7 2.0 2.5 -1.3 -1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.2 0.3 0.2 -0.5
Illnesses of father: Heart disease 0.1 0.2 0.2 -0.5 0.4
Illnesses of siblings: Diabetes 0.3 0.3 0.4 0.5 0.6
Smoking status: Previous 0.9 1.3 2.0 0.8 -1.4
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.4 0.7 0.9 0.2
Whole body fat-free mass 0.3 2.0 3.8 -0.4 -1.9
Leg fat-free mass (right) 0.5 2.5 3.1 -1.4 -1.8
Arm fat percentage (left) 0.3 1.3 2.4 -0.4 -1.6
Average weekly red wine intake 0.2 0.3 0.5 0.1 -0.7
Handedness (chirality/laterality): Left-handed 0.3 0.4 0.7 0.8 0.2
Mood swings 0.4 0.7 1.5 -0.1 1.2
Loneliness, isolation 0.5 0.7 0.8 0.9 -0.8
Long-standing illness, disability or infirmity 1.3 2.1 3.5 -1.9 -0.8
Ever had bowel cancer screening 0.5 0.5 0.6 0.7 0.7
Diabetes diagnosed by doctor 1.4 2.3 3.3 -1.8 -1.1
Ever had stillbirth, spontaneous miscarriage or termination 0.9 1.0 1.6 1.3 -0.6
Friendships satisfaction 0.5 0.7 0.7 -0.8 0.8
Qualifications: nursing, teaching 0.3 0.5 1.1 1.0 -0.1
Commuting to job workplace: Walk 0.5 0.6 1.1 1.1 0.1
Eye problems/disorders: Cataract 2.1 2.4 4.5 2.1 -0.5
Mouth/teeth dental problems: Mouth ulcers 0.4 0.7 1.3 0.0 1.2
Medication for cholesterol 0.1 0.1 0.2 0.4 -0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.2 1.4 1.7 -1.1 1.3
Back pain experienced in last month 0.3 0.5 0.8 0.3 -0.9
Mineral and other dietary supplements 0.1 0.2 0.4 -0.1 -0.6
Breast cancer (self-reported) 0.2 0.2 0.4 -0.6 0.2
Asthma (self-reported) 0.6 1.2 2.0 -0.6 1.4
Osteoporosis (self-reported) 4.1 5.1 9.8 0.6 3.1
Osteoarthritis (self-reported) 0.2 0.3 0.6 -0.8 -0.1
Medication: Aspirin 1.2 1.6 1.8 -1.2 -1.4
Medication: Gliclazide 0.2 0.2 0.4 0.2 -0.6
Illnesses of father: None of the above (group 1) 0.3 0.3 0.7 0.1 -0.8
Smoking status: Current 1.9 3.0 5.9 -2.4 -0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 2.7 5.8 11.6 3.4 0.1
Whole body water mass 0.3 1.9 3.7 -0.4 -1.9
Leg predicted mass (right) 0.5 2.6 3.2 -1.4 -1.8
Arm fat mass (left) 0.4 1.8 3.6 0.2 -1.9
Number of self-reported non-cancer illnesses 0.2 0.3 0.5 -0.7 -0.2
Average weekly champagne plus white wine intake 0.7 1.0 1.0 -1.0 -1.0
Miserableness 0.6 1.1 2.1 0.3 1.4
Guilty feelings 0.0 0.1 0.1 -0.3 0.2
Wears glasses or contact lenses 1.0 1.1 2.3 1.5 -0.2
Ever taken oral contraceptive pill 0.2 0.2 0.3 0.2 -0.6
Hearing aid user 0.6 0.6 1.3 -0.1 -1.1
Mother’s age at death 0.2 0.3 0.3 -0.6 0.5
Financial situation satisfaction 0.1 0.2 0.3 -0.3 0.5
Tinnitus: Yes, now most or all of the time 0.1 0.1 0.1 0.3 0.4
Commuting to job workplace: Public transport 1.7 2.0 2.9 1.7 1.1
Eye problems/disorders: Glaucoma 0.1 0.1 0.1 0.4 -0.2
Medication: Blood pressure 0.7 1.3 1.3 -1.1 -1.1
Pain type(s) experienced in last month: Hip pain 0.6 0.7 1.3 -0.3 1.1
Supplements: Fish oil (including cod liver oil) 1.0 1.3 1.6 0.9 1.3
High cholesterol (Self-reported) 0.2 0.4 0.5 -0.7 0.4
Medication: Bendroflumethiazide 0.9 1.4 2.8 -1.7 -0.2
Medication: Paracetamol 0.2 0.3 0.6 0.8 0.2
Medication: Lisinopril 1.9 2.4 4.6 -2.1 -0.4
Medication: Atorvastatin 0.6 0.8 1.1 -0.7 -1.0
Illnesses of father: High blood pressure 0.3 0.4 0.7 0.8 0.1
Alcohol drinker status: Never 0.0 0.0 0.1 -0.3 -0.1
Ever smoked 0.2 0.4 0.8 -0.1 -0.9
Basal metabolic rate 0.4 2.2 4.4 -0.3 -2.1
Leg fat percentage (left) 1.2 4.4 8.3 0.7 -2.9
Arm fat-free mass (left) 0.6 2.9 5.8 0.1 -2.4
Number of operations (self-reported) 0.1 0.2 0.4 0.1 0.6
Average weekly beer plus cider intake 0.8 1.1 2.3 -1.5 -0.0
Irritability 0.5 0.8 1.5 -0.2 1.2
Risk taking 0.3 0.4 0.4 -0.6 0.6
Ever had prostate specific antigen (PSA) test 0.1 0.1 0.1 -0.2 -0.3
Fractured/broken bones in last 5 years 2.7 3.5 5.9 -2.4 1.1
Age started oral contraceptive pill 0.8 1.0 1.9 -0.3 1.4
Diastolic blood pressure, automated reading 0.4 1.1 2.2 0.2 -1.5
Ever depressed for a whole week 3.9 4.8 5.8 1.9 2.4
Unable to work because of sickness or disability 0.7 1.0 1.5 0.7 1.2
Commuting to job workplace: Cycle 0.1 0.1 0.3 -0.5 0.1
Myopia 1.7 2.5 4.8 0.5 2.2
Vascular/heart problems diagnosed by doctor 1.1 3.1 3.9 1.5 2.0
Cholesterol lowering medication 0.9 1.3 1.8 -0.9 1.3
Medication: Omeprazole (e.g. Zanprol) 0.0 0.0 0.0 0.2 0.1
Pain experienced in last month 1.3 2.2 3.1 1.8 1.1
Supplements: Calcium 0.9 1.0 2.1 -1.4 -0.0
Basal cell carcinoma (self-reported) 1.1 1.3 1.5 1.2 1.0
Heart attack/myocardial infarction (self-reported) 1.3 1.6 2.7 -1.6 -0.8
Deep venous thrombosis (DVT) (self-reported) 1.4 1.9 3.7 1.9 0.1
Heart disease (siblings) 4.4 5.4 8.6 -1.4 2.9
Alcohol drinker status: Previous 0.8 0.9 1.5 1.2 -0.5
Pack years of smoking 0.3 0.5 0.8 -0.9 0.3
Impedance of whole body 0.1 0.7 1.0 0.7 1.0
Leg fat mass (left) 0.9 3.7 7.2 0.3 -2.7
Arm predicted mass (left) 0.6 3.3 6.6 0.2 -2.6