Hub : Genes

ZNF283

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0970	0.0280	7.6e-06	0.125	0.045	0.107	0.1	0.122	5.1e-15	3.2e-06	6.6e-13	3.4e-12	1.3e-14
2	GTEx	Cells Transformed fibroblasts	0.0780	0.0340	3.3e-03	0.002	NA	0.023	NA	0.006	2.4e-01	NA	6.9e-03	NA	1.2e-01
3	GTEx	Liver	0.3280	0.1140	1.7e-03	0.279	NA	0.233	NA	0.261	2.0e-08	NA	3.7e-07	NA	6.2e-08
4	GTEx	Thyroid	0.1580	0.0600	2.9e-03	0.043	NA	0.079	NA	0.048	2.9e-04	NA	1.2e-06	NA	1.4e-04
5	TCGA	Kidney Renal Clear Cell Carcinoma	0.0188	0.0112	3.6e-03	0.013	0.016	0.007	NA	0.006	1.0e-02	5.9e-03	4.4e-02	NA	5.8e-02
6	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0760	0.0470	9.1e-03	0.046	0.023	0.013	NA	0.026	1.2e-03	1.8e-02	5.9e-02	NA	1.2e-02
7	TCGA	Lung Adenocarcinoma	0.0912	0.0384	1.9e-06	0.051	0.040	0.044	NA	0.039	1.4e-06	1.7e-05	6.1e-06	NA	2.0e-05
8	TCGA	Prostate Adenocarcinoma	0.0784	0.0336	2.2e-05	0.024	0.046	0.041	NA	0.027	1.3e-03	1.4e-05	3.9e-05	NA	7.1e-04
9	TCGA	Thyroid Carcinoma	0.0800	0.0340	2.3e-04	0.009	0.053	0.043	NA	0.032	4.4e-02	6.2e-06	4.6e-05	NA	4.0e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.4	0.6	1.8	-1.4	-0.5	0.1	0.8	-0.8	1.0	0.2	-0.9	-0.6
Bipolar Disorder or Schizophrenia	0.4	0.9	2.5	-1.6	-0.8	0.5	1.3	-0.4	1.4	0.7	-0.4	-0.0
Depressed Affect (Nagel 2018)	0.3	0.6	2.6	0.4	-0.5	0.0	-0.1	1.3	1.6	-0.1	0.5	0.8
Depression (Nagel 2018)	0.2	0.3	0.9	0.8	0.2	-1.0	-0.4	-0.6	0.5	-0.6	-0.6	-0.2
Intelligence (Savage-Jansen 2018)	0.0	0.1	0.3	-0.3	0.5	0.4	-0.4	0.3	-0.0	0.4	-0.2	-0.5
Neuroticism (Nagel 2018)	0.1	0.3	1.0	-0.1	-0.4	-0.2	-0.1	0.5	1.0	-0.5	-0.7	-0.5
Schizophrenia (2018)	0.2	0.5	1.0	-0.9	-0.7	0.6	1.0	0.1	0.9	0.7	0.2	0.4
Schizophrenia vs Biploar Disorder	0.9	1.2	3.9	1.4	-0.3	-0.6	-1.2	0.1	-2.0	-0.9	-0.6	-1.5
Worry (Nagel 2018)	0.4	0.9	3.7	-0.4	-0.8	-0.4	-0.1	-0.6	-0.1	-1.1	-1.6	-1.9
Alzheimer’s Disease (in mother)	0.5	0.5	1.4	1.0	0.9	-0.3	-0.1	-1.2	-0.8	-0.2	0.6	0.8
Alzheimer’s Disease (in father)	0.5	0.6	2.0	-0.7	0.5	-0.5	1.2	-1.4	-0.1	-0.1	-0.7	-0.3
Alzheimer’s Disease (including proxy)	1.5	2.2	7.6	1.8	1.9	-1.5	0.1	-2.8	-1.4	-1.1	-0.4	0.3
Crohns Disease (2017)	0.6	1.2	2.5	0.6	1.2	-1.3	-0.5	-1.6	-0.4	-1.2	-1.4	-1.2
Irritable Bowel Disease (IBD)	0.3	0.8	1.8	0.6	1.1	-0.9	-0.3	-1.3	-1.0	-0.9	-0.7	-0.6
Ulcerative Colitis (UC)	0.1	0.1	0.6	0.3	0.2	0.1	-0.0	-0.1	-0.8	-0.0	0.4	0.3
Major Depression (MDD)	0.7	0.8	2.5	0.5	1.6	-0.8	-0.5	-1.0	-0.7	-1.2	-0.6	-0.7
Reaction Time	0.7	1.3	2.6	-1.3	-0.4	1.4	1.2	1.6	-0.2	1.5	1.0	0.2
Verbal and Numeric Reasoning (VNR)	0.4	1.0	2.4	1.1	0.6	-0.6	-1.5	-0.4	-1.1	-0.8	-0.9	-1.2
Breast Cancer	7.7	18.5	65.3	1.8	4.3	-5.0	-0.7	-8.1	-3.2	-4.0	-4.4	-2.8
Ovarian Cancer	0.8	1.1	2.1	0.8	-1.0	-0.8	-1.1	-0.5	-1.0	-0.9	-1.4	-1.4
Prostate Cancer	0.4	0.5	1.5	0.6	1.1	0.2	-0.6	-0.3	-1.2	0.1	0.9	0.5
Age at First Birth	1.7	2.4	7.6	-0.8	-2.8	0.9	-2.0	0.7	-1.6	-0.0	-1.2	-2.1
Bipolar Disorder (2011)	0.7	0.7	1.6	-0.8	-0.6	-0.4	0.6	-0.6	1.2	-0.3	-1.3	-0.9
Body Mass Index (BMI) (2010)	0.4	0.6	1.2	0.4	0.6	-0.7	-0.9	-0.5	-0.6	-0.7	-1.1	-0.9
Coronary Artery Disease (CAD)	0.1	0.1	0.4	-0.2	-0.4	0.1	0.1	0.1	0.6	-0.1	0.2	-0.1
Crohns Disease (2012)	0.4	0.6	1.8	0.1	-0.6	-0.5	-0.4	-1.1	-0.6	-0.6	-1.0	-1.3
Mean Putamen Volume	1.5	1.7	4.2	-0.1	1.6	-0.4	1.7	-0.3	2.0	0.4	1.1	2.1
Fasting Glucose	0.3	0.4	1.7	-0.1	-1.3	0.6	-0.4	0.7	-0.4	0.5	0.7	-0.1
HbA1C	0.4	0.4	1.3	0.5	-0.6	-0.0	-0.0	-1.1	-0.4	-0.6	-0.9	-0.8
HDL Cholesterol	0.1	0.2	1.3	-0.1	0.2	0.0	0.3	0.3	1.1	-0.0	-0.5	0.1
LDL Cholesterol	1.1	1.8	3.8	1.9	1.8	-1.7	-0.3	-1.5	-0.9	-1.5	-0.9	-0.3
Lupus	0.2	0.3	0.7	0.1	0.6	-0.5	-0.1	-0.9	-0.8	-0.6	-0.3	-0.7
Neuroticism (2016)	0.2	0.2	0.7	-0.8	0.1	0.4	0.4	0.3	0.5	0.0	-0.5	-0.7
Primary Biliary Cirrhosis	0.7	1.0	2.4	-1.4	-0.8	0.8	1.6	0.1	1.3	1.2	0.5	0.5
Rheumatoid Arthritis	1.2	1.6	5.0	-0.8	-0.3	0.9	1.6	0.3	0.3	1.2	2.0	2.2
Schizophrenia (2014)	0.2	0.5	1.5	-1.2	-0.4	0.2	1.1	-0.6	0.6	0.3	-0.5	-0.7
Triglycerides	0.1	0.1	0.9	-0.0	0.1	-0.1	0.1	-0.2	-1.0	-0.1	0.5	-0.1
Type 2 Diabetes (T2D) (2012)	0.3	0.4	1.8	-0.4	0.1	-0.0	0.7	-1.3	0.0	-0.1	-0.7	-0.5
Ulcerative Colitis	0.2	0.3	1.1	0.3	0.7	-0.2	0.4	-1.0	-0.3	0.3	0.8	0.5
Blood Eosinophil Count	0.6	4.6	10.6	3.3	2.1	-2.1	-2.9	-1.1	-2.5	-1.8	-1.3	-1.1
Blood Platelet Count	0.4	4.2	13.8	1.4	2.1	0.6	1.3	0.2	1.1	1.6	3.5	3.7
Blood Red Count	0.4	4.0	18.0	3.1	4.2	-1.4	-0.4	-1.1	0.3	-1.2	1.1	1.7
Blood White Count	0.3	1.9	6.5	2.4	2.5	-0.7	0.1	-1.3	0.2	-0.5	0.7	1.3
Heel T-Score	2.4	19.1	31.9	4.9	1.4	-4.1	-5.7	-3.2	-5.5	-5.0	-3.6	-4.4
BMI	0.6	3.2	7.5	1.9	0.9	-1.1	-2.5	-0.7	-2.7	-2.0	-1.5	-1.8
Height	0.2	3.3	6.0	1.4	-2.1	-0.1	-2.4	0.4	-1.9	-1.5	-2.5	-2.4
Waist Hip Ratio (WHR)	1.8	7.9	13.7	3.7	2.4	-3.4	-2.4	-3.1	-2.0	-3.7	-2.1	-1.7
Systolic Blood Pressure	0.1	0.4	1.3	0.4	-0.2	0.6	-0.6	0.7	-0.1	0.5	1.2	0.6
Smoking Status	0.2	0.4	0.8	-0.9	-0.3	0.9	0.8	0.4	0.3	0.7	0.3	0.2
Allergy or Eczema	1.1	3.0	8.6	0.5	1.1	-2.9	0.7	-2.5	-0.1	-1.8	-2.2	-1.5
Cardiovascular Disease	1.5	4.8	13.3	3.7	2.6	-2.4	-2.3	-1.6	-2.0	-2.3	-0.6	-0.7
Hypothyroidism (self reported)	0.3	0.7	1.9	0.6	1.3	-0.7	0.5	-1.4	-0.9	-0.2	0.7	0.7
Respiratory disease	0.2	0.5	1.7	0.0	0.3	-0.4	1.3	-0.1	0.4	0.4	0.9	1.2
Type 2 Diabetes (T2D) (2018)	0.7	1.4	4.5	-0.6	0.0	1.0	1.0	0.9	0.6	1.2	2.1	1.7
Lung FEV1/FVC ratio	0.2	1.2	3.0	0.5	0.3	-0.7	-1.2	-0.7	-1.2	-1.3	-1.5	-1.7
Lung FVC	0.0	0.2	0.3	0.2	0.1	-0.4	-0.6	-0.5	-0.3	-0.5	-0.4	-0.5
Neuroticism	0.1	0.3	0.7	0.4	0.3	-0.1	-0.6	0.5	0.6	-0.9	-0.5	-0.5
Chronotype (morning person)	0.9	2.2	5.5	-1.2	-2.3	1.9	-1.3	2.3	0.2	1.1	0.1	-0.7
Hair Pigment	0.5	13.1	22.3	-4.6	-3.1	4.1	2.7	3.8	4.2	4.7	2.4	1.8
Tanning	0.1	1.7	8.5	0.1	1.1	-0.6	-1.0	-1.3	-2.9	-0.7	-1.0	-1.2
Hand grip strength (left)	0.5	1.3	3.5	0.8	0.1	-0.7	-1.1	-1.0	-1.0	-0.9	-1.9	-1.5
Number of treatments/medications taken	1.7	3.1	7.5	2.7	2.4	-2.6	0.1	-1.9	-0.9	-1.8	-0.2	0.4
Average weekly spirits intake	1.4	1.7	3.7	1.7	1.3	-1.2	-1.2	-1.0	-1.4	-1.9	-0.7	-0.5
Sensitivity / hurt feelings	0.3	0.5	2.5	-0.7	-0.0	1.0	0.0	1.6	0.6	0.4	0.5	0.3
Frequency of depressed mood in last 2 weeks	0.6	0.9	2.3	1.3	0.6	-1.5	0.0	-1.1	0.1	-1.1	-0.8	-0.2
Hearing difficulty/problems: Yes	1.0	1.5	2.9	0.4	0.5	-1.7	0.3	-1.7	-0.8	-1.5	-1.6	-1.2
Relative age of first facial hair	0.1	0.3	0.6	-0.2	0.4	0.6	0.6	-0.2	-0.1	0.7	0.8	0.4
Other serious medical condition/disability diagnosed by doctor	0.4	0.6	1.8	0.5	1.0	-1.4	0.0	-1.0	0.3	-0.8	-0.6	0.2
Ever used hormone-replacement therapy (HRT)	0.4	0.4	1.1	0.2	-0.3	-0.5	1.0	-0.6	0.8	-0.2	0.8	1.0
Ever had hysterectomy (womb removed)	1.0	1.2	2.7	1.5	1.6	-1.4	-0.4	-0.8	-0.9	-0.8	0.6	1.0
Systolic blood pressure, automated reading	0.1	0.2	0.7	-0.1	-0.9	-0.1	-0.7	0.1	0.0	-0.4	-0.4	-0.7
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	0.9	-0.4	0.6	0.5	0.5	0.9	0.6	0.6	0.7	0.9
Angina	0.5	0.7	2.1	-0.8	0.2	1.4	0.4	0.5	-0.9	0.7	1.3	0.3
Medication for hormone replacement therapy	1.2	1.3	4.4	-0.6	0.4	0.7	1.0	0.5	0.1	1.1	2.0	2.1
Vitamin and mineral supplements	0.3	0.4	0.8	-0.6	-0.2	0.7	0.7	0.8	0.9	0.6	0.4	0.6
Supplements: Zinc	0.3	0.3	0.6	0.5	-0.4	0.1	-0.7	0.6	-0.7	0.3	0.8	0.7
Medication: Co-codamol	0.5	0.5	1.2	1.1	1.0	-0.9	0.5	0.4	0.4	-0.6	0.5	0.8
Medication: Metformin	0.6	0.9	2.7	-0.5	0.6	0.4	0.9	0.4	0.7	0.7	1.6	1.6
Diabetes (father)	2.0	2.4	4.1	-1.4	-0.1	1.7	1.7	1.5	1.3	2.0	1.8	1.8
Diabetes (mother)	0.3	0.4	0.7	-0.2	-0.5	0.6	0.6	0.7	0.4	0.4	0.8	0.8
Severe depression (siblings)	0.2	0.3	0.8	0.5	0.8	-0.4	-0.5	-0.5	-0.9	-0.1	0.1	0.1
Pack years adult smoking proportion	0.2	0.3	1.4	0.5	1.2	-0.6	0.4	-0.2	0.1	-0.1	0.2	0.7
Impedance of leg (right)	0.6	2.7	7.1	-0.7	0.4	1.2	1.4	1.5	1.4	2.0	2.7	2.3
Leg fat-free mass (left)	0.9	4.7	9.2	2.3	-0.3	-1.6	-2.5	-1.1	-1.9	-2.9	-3.0	-2.5
Trunk fat percentage	0.5	2.0	5.8	2.2	0.2	-0.1	-2.4	0.7	-2.3	-1.2	0.0	-0.5
Hand grip strength (right)	0.5	1.4	5.3	-0.0	0.8	-0.9	0.1	-2.3	-0.3	-0.9	-1.9	-1.2
Townsend deprivation index at recruitment	2.0	2.8	5.7	-2.0	0.3	1.9	1.5	0.9	0.8	2.4	2.1	1.9
Current tobacco smoking	1.6	2.6	5.6	-2.4	-1.9	1.9	1.3	1.7	1.4	1.8	0.6	0.3
Average weekly fortified wine intake	0.5	0.6	2.5	-0.9	0.3	-0.3	0.7	-1.6	0.7	0.5	-0.6	0.3
Maternal smoking around birth	0.4	0.6	2.6	0.6	1.6	-1.0	0.2	-0.8	-0.1	-0.5	-0.4	0.1
Fed-up feelings	0.5	1.0	3.6	1.9	0.7	-1.1	-0.9	-0.1	-0.0	-1.5	-0.3	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.7	2.2	1.2	1.5	-1.2	-0.3	-0.6	0.1	-0.9	-0.5	0.0
Relative age voice broke	0.3	0.4	1.3	-0.9	0.7	0.3	1.1	-0.7	-0.3	0.7	0.3	0.0
Taking other prescription medications	0.9	1.4	4.0	2.0	0.5	-1.7	-0.9	-1.0	-0.7	-1.5	-0.6	0.2
Age when periods started (menarche)	0.3	0.8	3.3	1.0	1.8	-0.9	-0.2	-1.2	-0.6	-0.6	-0.1	0.3
Bilateral oophorectomy (both ovaries removed)	1.0	1.1	3.3	0.6	0.7	0.8	-0.4	1.8	-0.4	0.4	1.8	1.2
Heel bone mineral density (BMD) T-score, automated (left)	4.4	9.9	14.4	3.0	0.6	-3.1	-3.7	-2.4	-3.5	-3.4	-3.4	-3.8
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.9	-0.3	0.0	-0.1	0.5	-1.0	-0.2	0.3	0.2	0.4
Qualifications: CSEs or equivalent	0.8	1.0	3.0	-0.2	-0.6	1.4	-1.2	0.7	-1.7	0.7	1.2	0.4
Serious illness, injury or assault to yourself	0.6	0.7	1.4	0.9	0.9	-0.8	-1.2	-0.4	-0.1	-1.1	-0.9	-0.4
High blood pressure	0.5	1.4	5.3	2.3	0.9	-0.9	-1.3	-0.2	-1.5	-1.2	0.3	-0.1
Hayfever, allergic rhinitis or eczema	2.0	4.4	10.2	1.2	1.1	-3.2	-0.2	-2.8	-1.5	-2.4	-2.6	-2.1
Multivitamins +/- minerals	0.4	0.4	1.0	0.9	-0.2	-0.4	-1.0	-0.1	-0.7	-0.6	-0.5	-1.0
Stomach or abdominal pain in last month	1.2	1.5	4.7	-0.5	0.4	-1.1	0.7	-2.2	0.7	-0.9	-1.8	-1.4
Supplements: Glucosamine	0.1	0.2	0.7	-0.0	-0.7	-0.1	-0.2	-0.3	-0.8	-0.1	0.3	-0.2
Diverticular disease/diverticulitis (self-reported)	0.5	0.5	2.6	0.1	0.5	-0.7	-0.2	-1.6	-0.8	-0.7	-0.3	-0.3
Medication: Atenolol	0.2	0.2	0.6	-0.1	0.2	0.5	0.8	0.7	0.0	-0.1	0.6	-0.3
Medication: Levothyroxine sodium	1.0	1.6	3.4	1.6	1.2	-1.5	0.7	-1.8	-1.6	-1.0	0.5	0.8
Sitting height	0.6	4.4	9.5	2.2	-0.3	-2.2	-1.5	-2.1	-1.5	-2.7	-3.1	-2.1
Chronic bronchitis/emphysema (father)	0.4	0.5	1.2	1.0	0.9	-0.3	-0.6	-0.5	-1.1	-0.4	0.7	0.7
High blood pressure (mother)	0.3	0.4	2.0	0.8	-0.8	0.3	-0.4	1.4	-0.3	-0.1	0.2	-0.2
Body mass index (BMI)	0.6	2.4	4.6	2.2	0.6	-1.2	-2.0	-0.6	-2.0	-2.0	-1.2	-1.0
Impedance of leg (left)	0.5	2.3	6.0	-0.9	-0.3	1.6	0.9	1.8	1.0	2.0	2.5	1.6
Leg predicted mass (left)	0.9	4.6	9.4	2.2	-0.3	-1.6	-2.4	-1.1	-1.8	-2.8	-3.1	-2.5
Trunk fat mass	0.5	2.3	6.3	2.3	-0.0	-0.4	-2.5	0.3	-2.3	-1.6	-0.7	-0.9
Waist circumference	0.9	3.4	6.2	2.5	0.7	-1.8	-2.2	-1.1	-1.9	-2.5	-1.7	-1.4
Number of incorrect matches in round	1.2	2.0	6.1	-0.9	0.3	0.6	2.5	0.2	1.6	1.2	1.4	2.1
Past tobacco smoking	0.2	0.3	0.8	-0.1	-0.5	0.7	-0.9	0.7	-0.3	0.5	0.6	0.5
Alcohol usually taken with meals	0.5	0.8	2.2	0.7	-0.1	-1.4	-0.1	-1.5	0.2	-0.9	-1.2	-0.5
Nervous feelings	0.6	1.1	3.3	0.2	-0.7	-0.1	-1.1	0.7	-0.4	-1.3	-1.4	-1.8
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.7	2.0	0.8	0.9	-0.8	1.0	0.3	1.4	-0.4	0.3	0.9
Hearing difficulty/problems with background noise	1.2	2.0	3.6	0.8	-0.2	-1.9	-0.6	-1.7	-1.4	-1.6	-1.7	-1.6
Hair/balding pattern: Pattern 2	0.4	0.5	1.6	0.3	-0.6	0.2	-1.3	0.5	-0.6	-0.1	-0.5	-1.1
Had menopause	0.4	0.5	0.9	-0.9	-0.8	0.7	0.5	0.4	0.6	0.7	0.9	0.5
Had other major operations	0.8	1.0	2.1	-1.2	0.2	0.8	1.4	0.1	0.5	0.9	1.4	1.4
Forced vital capacity (FVC)	0.1	0.5	1.4	-0.7	-1.2	1.0	0.2	0.9	0.3	0.5	0.0	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	3.9	9.0	12.8	2.6	0.9	-2.9	-3.5	-2.5	-3.5	-3.2	-3.3	-3.6
Ever unenthusiastic/disinterested for a whole week	1.9	2.3	4.8	1.5	1.2	-1.8	-1.4	-1.0	-0.6	-2.2	-1.9	-1.5
Qualifications: None of the above	3.5	7.5	15.0	-2.1	0.4	2.0	3.5	1.6	3.4	2.6	3.4	3.9
Financial difficulties in last 2 years	0.8	1.0	2.5	0.8	1.2	-1.0	-0.9	-1.6	-0.8	-1.0	-0.9	-0.4
Mouth/teeth dental problems	2.6	3.9	7.8	2.3	1.5	-2.3	-1.3	-1.9	-1.3	-2.8	-2.2	-1.8
Heart attack	0.9	1.1	2.0	-1.1	-0.7	1.4	0.6	1.3	0.4	1.3	1.3	0.9
Allergy	0.7	1.7	5.7	-1.0	-0.6	2.4	-0.7	1.8	0.7	1.3	1.2	0.7
Pain all over the body in last month	0.3	0.3	1.0	0.3	0.1	-0.3	0.6	0.3	1.0	0.0	0.4	1.0
Diabetes (self-reported)	0.3	0.5	1.8	-0.2	0.5	-0.2	1.0	-0.0	0.1	0.2	1.2	1.4
Hayfever/allergic rhinitis (self-reported)	2.4	3.2	8.6	-0.2	0.3	-2.6	1.0	-2.8	0.4	-1.4	-2.9	-1.5
Medication: Ramipril	0.2	0.3	0.7	0.5	0.8	-0.6	0.6	-0.5	-0.1	-0.2	0.5	0.4
Medication: Simvastatin	0.9	1.4	3.2	1.1	1.8	-1.3	-0.7	-1.5	-0.5	-0.9	-1.1	-0.9
Fluid intelligence score	0.7	1.4	4.4	-0.2	-0.4	-0.4	-1.5	-1.0	-1.6	-0.4	-1.3	-2.1
Illnesses of siblings	0.2	0.3	0.7	-0.8	-0.6	0.1	0.6	0.1	0.1	0.4	-0.8	-0.4
Neuroticism score	0.3	0.6	1.7	0.8	-0.3	-0.5	-1.0	0.4	0.1	-1.3	-1.0	-0.9
Weight	0.8	4.0	6.8	2.6	0.0	-1.4	-2.6	-0.8	-2.2	-2.6	-2.2	-1.8
Impedance of arm (right)	0.3	1.3	4.2	-0.5	-0.3	1.3	0.2	1.3	0.2	1.4	2.0	1.2
Arm fat percentage (right)	0.5	1.9	5.1	2.2	0.6	-0.8	-2.0	-0.1	-1.9	-1.7	-0.4	-0.5
Trunk fat-free mass	0.6	3.4	10.6	1.4	-0.7	-1.6	-1.5	-1.2	-0.9	-2.4	-3.2	-2.2
Hip circumference	0.3	1.1	2.6	1.4	-0.3	-0.6	-1.6	0.3	-1.2	-1.3	-1.0	-0.8
Time employed in main current job	0.8	0.9	3.1	0.2	1.6	-1.0	0.1	-1.8	-0.3	-0.9	-0.9	-0.1
Alcohol intake versus 10 years previously	0.2	0.2	0.9	0.2	-0.6	0.7	-0.5	0.9	-0.2	0.1	0.2	-0.4
Father’s age at death	0.2	0.3	0.9	-0.4	0.1	-0.4	-0.4	-0.4	0.3	-0.3	-1.0	-0.8
Worrier / anxious feelings	0.6	1.2	3.3	0.2	-0.6	-0.4	-0.8	-1.0	-1.1	-1.2	-1.5	-1.8
Frequency of tiredness / lethargy in last 2 weeks	2.0	3.3	7.1	1.6	2.7	-2.5	1.4	-2.1	1.6	-1.3	-0.2	1.5
Falls in the last year	0.9	1.2	4.8	1.0	1.2	-1.4	-0.5	-2.2	-0.5	-0.9	-0.6	-0.2
Hair/balding pattern: Pattern 3	0.3	0.5	2.0	0.0	-1.4	0.3	-0.4	0.4	-0.6	-0.6	-0.7	-0.9
Number of live births	1.4	1.9	6.6	-1.1	-0.3	0.6	2.6	0.1	2.0	1.2	1.3	1.5
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	0.9	-0.0	-0.5	0.4	-0.9	0.3	-0.3	-0.3	-0.8	-0.9
Pulse rate	0.3	0.5	2.3	0.6	0.7	-0.1	0.4	-0.1	0.2	0.2	1.1	1.5
Happiness	0.7	0.8	2.8	0.2	-0.8	-0.6	-0.4	-0.7	0.1	-0.9	-1.4	-1.7
Noisy workplace	3.1	3.8	10.7	-0.3	-1.4	2.5	0.4	2.7	0.2	1.8	3.3	2.2
Qualifications: A levels/AS levels or equivalent	0.7	1.6	4.6	0.4	-0.3	-1.4	-0.6	-1.3	0.2	-1.1	-2.1	-2.1
Serious illness, injury or assault of a close relative in last 2 years	2.6	3.0	5.9	2.4	0.5	-1.9	-0.7	-1.9	-2.1	-2.4	-1.1	-1.3
Mouth/teeth dental problems: Dentures	5.8	9.7	18.8	-4.3	-2.8	3.5	2.4	3.2	3.1	4.0	2.2	1.6
Asthma	0.9	1.8	5.5	1.3	1.5	-2.0	0.2	-2.4	-0.7	-1.3	-0.8	-0.2
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	1.8	0.7	1.1	-0.7	-0.4	-1.1	-1.4	-0.7	0.2	0.1
Medication: Cholesterol lowering	0.6	1.0	5.4	1.1	2.3	0.0	0.2	0.1	-0.1	-0.1	1.0	1.1
Depression (self-reported)	0.4	0.4	1.4	-0.6	-0.2	0.1	1.2	0.4	1.0	0.6	0.4	0.8
Medication: Lansoprazole	0.3	0.4	1.4	-0.4	-1.1	-0.4	1.2	-0.3	0.5	0.2	-0.3	0.3
Prospective memory result	0.2	0.2	0.5	-0.5	-0.7	0.5	0.0	0.4	0.7	0.3	-0.1	-0.0
Lung cancer (father)	0.8	0.9	3.1	0.4	0.3	0.8	0.5	0.5	-0.4	0.8	1.8	1.7
Illnesses of mother	0.3	0.4	1.9	-1.4	-0.5	0.4	0.4	-0.3	-0.1	0.4	-0.6	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.8	1.6	0.4	-0.3	-0.3	-1.2	-0.6	-1.0	-0.8	-1.2	-1.3
Pulse wave Arterial Stiffness index	0.5	0.6	2.1	1.1	1.4	-0.7	-0.3	-1.1	-0.4	-0.4	0.2	0.5
Impedance of arm (left)	0.3	1.2	4.6	-0.6	-0.2	1.3	0.3	1.0	0.0	1.4	2.1	1.2
Arm fat mass (right)	0.7	2.9	5.2	2.2	0.3	-1.2	-2.3	-0.6	-2.2	-2.2	-1.6	-1.4
Trunk predicted mass	0.6	3.3	10.4	1.4	-0.8	-1.5	-1.5	-1.1	-0.9	-2.4	-3.2	-2.2
Standing height	0.2	2.4	7.5	1.0	-1.4	-0.7	-1.5	-0.5	-0.9	-1.6	-2.7	-2.2
Length of working week for main job	0.2	0.2	0.8	0.1	0.1	0.5	0.0	0.6	0.9	0.4	0.4	0.2
Exposure to tobacco smoke at home	1.1	1.3	2.7	-1.5	-0.9	1.4	0.0	1.6	0.8	1.3	1.2	0.4
Breastfed as a baby	1.8	2.2	4.6	1.2	-0.7	-2.2	-0.7	-2.0	-0.9	-1.8	-1.9	-1.1
Tense / ‘highly strung’	0.4	0.7	2.6	-0.5	0.1	0.2	1.3	0.5	1.6	0.6	0.6	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.4	1.3	-0.2	-0.2	0.3	0.7	0.4	1.2	0.4	0.6	0.9
Hair/balding pattern: Pattern 4	0.4	1.0	2.5	0.7	1.6	-1.2	-0.6	-1.4	-1.1	-0.9	-0.2	-0.0
Birth weight of first child	2.8	5.0	9.1	1.6	1.0	-1.9	-3.0	-2.1	-2.3	-2.6	-2.6	-2.2
Peak expiratory flow (PEF)	0.3	0.7	1.4	-0.6	-1.1	0.6	-0.3	1.2	1.0	0.2	-1.0	-1.1
Pulse wave reflection index	0.9	1.1	3.0	0.9	0.9	-0.8	-1.1	-1.7	-1.4	-1.0	-0.6	-0.6
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.4	0.4	-0.2	-0.1	0.5	0.7	0.5	-0.3	-0.1	0.2
Loud music exposure frequency	0.4	0.4	1.2	0.4	0.3	-0.9	-0.3	-1.1	-0.5	-0.7	-0.4	-0.5
Qualifications: O levels/GCSEs or equivalent	2.0	3.2	10.2	0.5	-1.1	-0.6	-2.3	-0.7	-2.1	-1.3	-2.2	-3.2
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	3.5	-1.2	-0.1	1.7	0.5	1.7	0.7	1.9	1.6	1.0
Blood clot in the leg (DVT)	1.9	2.5	4.3	-1.3	-1.5	1.1	2.1	1.8	1.4	1.7	1.6	1.5
Medication: Paracetamol	0.2	0.4	2.4	-0.6	0.1	0.2	1.5	-0.1	0.4	0.5	0.6	0.4
Headache pain in last month	3.0	5.2	13.8	-2.9	-1.3	1.4	3.7	0.4	2.9	2.5	1.6	2.0
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	4.5	-2.1	-2.1	0.7	0.8	-0.1	0.4	1.0	-0.3	-0.3
Glaucoma (self-reported)	1.2	1.5	4.3	2.1	1.4	-1.2	-0.5	-1.2	-1.3	-1.2	0.5	0.8
Gout (self-reported)	0.6	0.8	3.9	2.0	0.9	-0.6	-0.7	0.1	-0.5	-1.0	0.7	0.5
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	1.3	0.6	0.2	-0.5	1.1	-0.9	-0.2	-0.0	0.9	1.1
Medication: Amlodipine	0.3	0.4	1.2	0.2	-0.4	0.9	0.2	0.7	-0.5	0.4	1.1	0.2
Medication: Ventolin 100micrograms inhaler	0.4	0.6	1.6	0.7	-0.0	-1.3	-0.3	-1.0	0.3	-1.0	-0.7	-0.2
Birth weight	0.3	0.7	1.8	0.2	-0.5	0.0	-0.7	0.9	1.0	-0.5	-1.3	-1.2
Chronic bronchitis/emphysema (mother)	2.6	3.1	6.8	-0.7	1.0	1.0	2.1	1.3	2.6	1.6	2.1	2.4
High blood pressure (siblings)	0.6	0.9	2.1	1.0	0.3	-0.3	-1.4	-0.4	-1.5	-1.0	-0.2	-1.3
Forced vital capacity (FVC), Best measure	0.0	0.2	0.8	-0.3	-0.9	0.5	-0.1	0.3	-0.3	0.1	-0.3	-0.4
Body fat percentage	0.5	1.8	5.1	2.2	0.4	-0.3	-2.1	0.6	-2.0	-1.3	0.1	-0.3
Leg fat percentage (right)	0.4	1.5	5.9	2.4	0.8	-0.8	-1.4	0.2	-1.6	-1.3	0.4	0.4
Arm fat-free mass (right)	0.6	3.0	8.8	1.3	-1.0	-1.1	-1.8	-0.6	-1.1	-2.1	-3.0	-2.2
Exposure to tobacco smoke outside home	1.0	1.4	2.7	-1.7	-0.4	1.2	1.5	0.4	1.2	1.5	1.2	0.7
Comparative body size at age 10	0.2	0.6	1.8	1.3	0.6	-0.5	-1.3	0.2	-0.2	-1.2	-0.6	-0.1
Number of full brothers	1.3	1.7	3.4	1.0	1.2	-1.2	-1.5	-1.3	-1.8	-1.5	-0.8	-0.9
Worry too long after embarrassment	1.1	1.9	3.9	1.9	0.5	-1.0	-1.7	-0.7	-1.7	-2.0	-0.9	-1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.7	2.1	0.2	1.1	-1.2	1.0	-1.4	-0.3	-0.7	-0.4	0.2
Wheeze or whistling in the chest in last year	0.1	0.2	0.6	0.6	0.1	-0.5	0.0	-0.4	-0.8	-0.1	0.5	0.6
Number of children fathered	0.3	0.4	0.9	0.5	-0.4	-0.1	-0.9	-0.1	-1.0	-0.7	-0.6	-0.6
Reason for reducing amount of alcohol drunk: Health precaution	3.1	3.6	6.8	1.5	1.8	-2.4	-0.3	-2.2	-0.5	-2.4	-2.6	-1.8
Age at first live birth	1.5	2.7	8.7	-0.3	-1.1	-1.1	-1.1	-1.3	-1.2	-1.2	-2.9	-2.7
Pulse wave peak to peak time	0.5	0.6	2.2	-0.9	-1.5	0.7	0.2	1.0	0.3	0.3	-0.3	-0.5
Health satisfaction	1.0	1.3	2.7	1.6	-0.4	-1.5	-1.1	-0.6	-0.3	-1.5	-1.5	-0.9
Shortness of breath walking on level ground	0.4	0.4	0.9	0.0	-0.6	0.1	-1.0	-0.0	-0.7	-0.8	-0.9	-0.9
Qualifications: College or University degree	1.2	3.7	6.8	1.5	0.6	-2.0	-1.5	-2.6	-1.8	-1.9	-2.5	-2.1
Eye problems/disorders: None of the above	0.1	0.2	0.4	0.6	0.4	-0.5	0.0	-0.3	-0.2	-0.5	-0.4	-0.2
Mouth/teeth dental problems: Loose teeth	1.4	1.7	7.3	0.0	0.3	-0.2	-1.1	-1.6	-2.7	-0.4	-0.9	-1.7
Emphysema/chronic bronchitis	0.9	1.1	2.8	-0.9	-0.7	1.3	0.7	1.7	0.6	1.3	1.1	0.5
Medication for pain relief, constipation, heartburn	0.4	0.7	1.6	-0.7	-0.8	1.2	-0.8	1.2	0.1	1.1	0.1	-0.2
Neck or shoulder pain in last month	0.1	0.1	0.3	-0.5	-0.4	0.3	0.3	0.2	-0.3	-0.2	-0.1	-0.3
Medication: Blood pressure	0.4	0.8	2.0	1.3	0.8	0.3	-0.5	0.9	-0.7	-0.1	1.4	1.0
Angina (self-reported)	1.0	1.3	3.6	-0.9	0.1	1.9	0.5	1.1	-0.6	1.1	1.9	0.6
Migraine (self-reported)	1.7	2.0	4.3	-1.4	-0.3	0.9	2.1	-0.4	0.7	1.7	1.9	2.1
Medication: Ibuprofen	0.3	0.4	1.4	0.2	1.2	-0.4	0.1	-0.9	-0.7	-0.5	0.1	-0.1
Medication: Allopurinol	0.2	0.3	1.6	1.2	0.0	-0.1	-0.4	0.8	-0.0	-0.5	0.4	0.1
Medication: Omeprazole	1.1	1.3	2.9	1.7	0.4	-1.5	-1.2	-1.2	-0.5	-1.6	-1.0	-0.3
Medication: Seretide 50 evohaler	0.1	0.1	0.5	-0.1	-0.5	0.2	0.2	-0.3	0.2	0.5	0.2	0.7
Mean time to correctly identify matches	0.6	1.2	3.1	-0.8	-0.3	1.5	0.8	1.8	-0.6	1.4	1.3	0.5
Heart disease (mother)	0.1	0.2	0.5	-0.2	-0.5	-0.2	-0.4	-0.1	-0.4	-0.2	-0.6	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	3.2	1.0	1.8	-1.1	-0.3	-0.8	0.2	-0.9	-0.3	0.3
Whole body fat mass	0.5	2.2	5.2	2.3	0.1	-0.7	-2.3	0.1	-2.0	-1.8	-1.0	-1.0
Leg fat mass (right)	0.6	2.4	7.3	2.7	0.5	-1.1	-2.1	-0.2	-1.9	-2.0	-0.8	-0.6
Arm predicted mass (right)	0.5	2.4	7.0	1.1	-1.2	-0.7	-1.7	-0.2	-1.0	-1.8	-2.6	-2.0
Pulse rate, automated reading	0.1	0.4	0.9	0.8	0.4	-1.0	0.9	-0.2	0.7	-0.5	-0.0	0.4
Alcohol intake frequency.	0.5	1.1	5.5	0.1	-1.2	1.2	-0.9	2.4	0.4	0.3	0.7	0.5
Comparative height size at age 10	0.1	0.8	3.0	0.2	-0.3	1.1	0.3	1.7	0.6	0.6	0.8	1.1
Number of full sisters	0.5	0.6	2.9	1.7	0.2	-0.6	-0.5	-0.1	-1.0	-0.7	0.6	0.6
Suffer from ‘nerves’	1.5	2.3	3.9	0.5	0.7	-1.7	-1.2	-1.7	-1.5	-1.7	-2.0	-1.9
Overall health rating	0.8	1.7	5.9	0.4	1.1	-0.5	2.0	-0.5	1.3	0.0	1.3	2.4
Chest pain or discomfort	1.1	1.6	4.9	0.2	-0.3	0.9	0.7	1.7	0.8	1.1	2.2	1.8
Had major operations	1.4	1.6	6.4	1.1	0.5	0.6	0.2	0.9	0.0	0.7	2.1	2.5
Age at last live birth	1.5	2.1	5.1	-0.1	-1.6	-0.2	-1.6	-0.4	-2.0	-0.9	-1.9	-2.3
Family relationship satisfaction	1.0	1.2	3.0	-1.7	-1.5	0.6	0.4	-0.0	0.8	0.8	-1.2	-1.3
Leg pain on walking	0.6	0.8	2.4	0.2	-0.7	-0.2	-1.2	-0.7	-1.6	-0.7	-0.8	-1.0
Qualifications: NVQ or HND or HNC or equivalent	1.6	2.0	3.5	1.4	1.0	-1.6	-1.4	-1.1	-1.9	-1.4	-1.3	-1.3
Commuting to job workplace: Car/motor vehicle	0.8	0.9	2.2	0.3	1.5	-1.3	0.2	-1.1	0.1	-0.7	-1.3	-0.9
Illness, injury, bereavement, stress in last 2 years	2.5	3.0	8.1	-2.9	-1.5	1.8	1.2	1.5	1.5	2.3	1.2	0.9
Medication: Aspirin	0.8	1.0	1.9	0.9	1.0	-1.3	0.1	-1.0	-0.9	-1.4	-1.0	-1.0
Supplements: Vitamin C	0.2	0.3	0.8	-0.1	0.3	-0.3	-0.8	-0.9	-0.9	0.1	0.2	0.3
Knee pain experienced in last month	1.4	2.2	5.6	-1.0	-2.4	2.0	0.9	1.5	0.6	1.4	1.5	1.0
Hypertension (Self-reported)	0.7	1.9	6.1	2.5	0.9	-1.3	-1.5	-0.7	-1.8	-1.5	-0.2	-0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	2.3	0.3	1.2	-0.9	1.5	-1.0	0.6	-0.2	0.4	0.9
Illnesses of father: Heart disease	0.6	0.8	2.3	0.6	0.1	-0.8	-0.8	-0.2	-0.5	-0.7	-1.5	-1.5
Illnesses of siblings: Diabetes	0.5	0.6	1.7	1.1	-0.1	-0.1	-1.3	-0.2	-1.1	-0.6	0.9	0.3
Smoking status: Previous	0.5	0.8	2.1	0.9	1.4	-1.1	1.1	-1.1	0.0	-0.7	-0.1	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.8	4.1	-2.0	-1.3	2.0	0.5	0.9	-0.0	1.8	1.3	0.7
Whole body fat-free mass	0.7	3.8	10.2	1.8	-0.6	-1.5	-1.9	-1.0	-1.2	-2.6	-3.2	-2.4
Leg fat-free mass (right)	0.9	5.0	10.9	2.0	-0.7	-1.3	-2.6	-1.0	-2.0	-2.8	-3.3	-2.9
Arm fat percentage (left)	0.4	1.5	3.9	2.0	0.4	-0.5	-1.9	0.1	-1.9	-1.4	-0.2	-0.4
Average weekly red wine intake	0.6	0.8	2.6	0.3	1.6	-1.2	0.7	-1.6	0.1	-0.3	-0.5	0.1
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.8	-0.3	-0.9	-0.1	-0.5	0.1	0.2	0.0	-0.2	-0.8
Mood swings	0.3	0.6	3.0	0.0	-0.5	0.1	0.7	0.9	1.7	0.0	0.5	0.6
Loneliness, isolation	0.1	0.1	0.2	-0.4	0.1	-0.2	0.1	0.2	0.5	-0.4	-0.4	-0.3
Long-standing illness, disability or infirmity	0.7	1.1	3.1	1.1	1.4	-1.8	0.4	-1.4	-0.2	-0.7	0.2	0.9
Ever had bowel cancer screening	0.2	0.2	0.6	-0.2	-0.7	-0.0	0.5	0.1	0.7	0.5	0.2	0.3
Diabetes diagnosed by doctor	0.7	1.1	3.7	-0.7	0.4	-0.3	1.9	-0.3	1.1	0.6	1.2	1.6
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.2	-0.1	0.1	-0.3	0.0	-0.2	-0.1	0.3	0.3	0.5
Friendships satisfaction	0.8	1.0	2.6	-1.4	-1.1	0.5	1.4	0.1	1.6	0.8	-0.5	-0.2
Qualifications: nursing, teaching	1.7	2.7	5.3	2.3	-0.2	-2.0	-1.5	-1.2	-1.3	-1.9	-1.7	-1.5
Commuting to job workplace: Walk	0.9	1.0	2.0	-1.4	-0.7	0.8	1.0	-0.2	0.4	1.3	1.2	1.0
Eye problems/disorders: Cataract	0.8	1.0	2.7	0.1	-1.6	0.2	-1.2	0.5	-0.9	-0.7	-0.8	-1.5
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.5	0.3	-0.5	-1.2	0.5	-1.2	-0.7	-0.7	-0.7	-0.4
Medication for cholesterol	0.2	0.4	1.1	-0.6	-0.3	0.8	-0.1	1.1	0.9	0.4	-0.1	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	2.2	1.4	0.4	-0.7	-1.5	-0.6	-1.4	-1.0	-0.5	-0.5
Back pain experienced in last month	0.3	0.4	1.7	0.1	-0.0	0.1	0.5	-0.7	-0.6	0.1	0.7	1.3
Mineral and other dietary supplements	0.2	0.3	1.9	-0.4	0.5	0.3	-0.1	0.2	1.4	0.1	-0.3	0.1
Breast cancer (self-reported)	2.2	2.7	6.5	-1.7	-1.7	2.4	-0.0	2.5	-0.1	1.6	1.8	0.5
Asthma (self-reported)	0.8	1.7	5.7	1.1	1.5	-1.9	0.4	-2.4	-0.3	-1.1	-0.7	0.1
Osteoporosis (self-reported)	1.1	1.3	4.1	-1.6	0.1	0.7	2.0	0.1	0.8	1.4	1.1	1.1
Osteoarthritis (self-reported)	0.2	0.3	1.2	-0.2	-1.1	0.5	0.2	0.7	0.4	0.3	0.0	0.3
Medication: Aspirin	0.7	0.9	1.5	1.0	1.2	-1.2	0.0	-0.9	-1.0	-1.2	-0.6	-0.7
Medication: Gliclazide	0.4	0.5	1.5	0.4	0.3	-0.1	0.8	0.5	0.3	-0.1	1.2	1.2
Illnesses of father: None of the above (group 1)	0.1	0.1	0.5	-0.0	-0.4	0.1	-0.7	-0.2	-0.4	-0.3	-0.1	-0.2
Smoking status: Current	1.5	2.4	4.6	-2.1	-1.8	2.0	0.9	1.9	1.3	1.8	0.6	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	3.0	0.1	0.3	-0.1	-1.7	-0.2	-0.9	-0.7	-0.8	-1.0
Whole body water mass	0.7	4.0	10.8	1.8	-0.6	-1.6	-1.9	-1.1	-1.3	-2.6	-3.3	-2.5
Leg predicted mass (right)	1.0	5.2	11.1	2.0	-0.6	-1.4	-2.7	-1.1	-2.0	-2.8	-3.3	-3.0
Arm fat mass (left)	0.7	3.0	5.6	2.2	0.2	-1.1	-2.4	-0.5	-2.2	-2.2	-1.6	-1.5
Number of self-reported non-cancer illnesses	1.5	2.6	7.7	1.2	2.0	-2.8	0.5	-2.7	-0.6	-1.1	-0.8	0.5
Average weekly champagne plus white wine intake	1.2	1.6	4.5	0.2	-0.5	-1.2	-1.4	-1.2	-0.5	-1.2	-2.1	-1.7
Miserableness	0.5	0.8	2.2	0.7	1.1	-0.5	0.3	0.4	1.5	-0.2	1.0	1.4
Guilty feelings	0.6	0.9	2.0	1.4	-0.2	-0.6	-1.3	-0.2	-0.7	-1.2	-0.8	-1.2
Wears glasses or contact lenses	0.4	0.4	1.2	0.3	0.6	-0.8	-0.2	-0.7	-0.4	-0.6	-1.1	-0.8
Ever taken oral contraceptive pill	0.5	0.5	1.6	1.3	0.9	-0.5	-0.1	-0.6	-1.1	-0.6	-0.0	0.3
Hearing aid user	0.3	0.3	1.3	1.1	0.0	-0.4	-0.7	-0.0	-0.6	-0.2	0.4	0.4
Mother’s age at death	0.4	0.4	1.7	-0.8	-1.3	0.3	0.8	0.4	0.5	0.6	-0.1	-0.2
Financial situation satisfaction	0.7	0.9	2.6	-0.2	-1.6	-0.3	-0.4	-0.3	0.4	-0.6	-1.5	-1.4
Tinnitus: Yes, now most or all of the time	1.4	1.6	3.2	1.0	1.2	-1.6	-1.0	-1.3	-0.8	-1.8	-1.5	-0.9
Commuting to job workplace: Public transport	0.7	0.9	2.2	1.5	1.4	-0.6	-1.1	-0.5	-1.0	-0.9	0.3	0.4
Eye problems/disorders: Glaucoma	0.7	0.8	2.5	1.6	1.0	-1.0	-0.2	-0.8	-0.8	-0.8	0.5	0.6
Medication: Blood pressure	0.2	0.4	1.1	1.0	-0.2	-0.5	-0.4	-0.3	-1.1	-0.4	-0.2	-0.8
Pain type(s) experienced in last month: Hip pain	0.7	0.9	2.6	0.8	-1.4	0.6	-1.5	1.6	-0.4	-0.4	-0.1	-0.5
Supplements: Fish oil (including cod liver oil)	0.4	0.6	2.3	1.5	0.9	-0.5	-0.3	-0.0	-1.0	-0.6	0.4	0.2
High cholesterol (Self-reported)	1.3	2.3	4.5	1.8	2.1	-1.6	-0.9	-2.0	-1.6	-1.2	-0.9	-0.9
Medication: Bendroflumethiazide	0.3	0.5	2.3	1.5	-0.6	-0.7	-0.9	-0.4	-0.4	-0.6	-0.1	-0.0
Medication: Paracetamol	0.2	0.3	1.2	0.6	0.4	-0.4	1.1	-0.2	0.6	-0.0	0.5	0.6
Medication: Lisinopril	0.2	0.3	0.7	0.6	0.7	-0.2	-0.1	0.5	0.4	-0.3	0.6	0.8
Medication: Atorvastatin	0.1	0.1	0.3	0.6	0.4	-0.3	0.1	0.0	-0.2	-0.3	0.4	0.4
Illnesses of father: High blood pressure	1.2	1.5	4.3	-1.0	-1.4	1.4	1.0	2.1	1.3	1.1	0.6	0.2
Alcohol drinker status: Never	0.7	0.8	2.7	-0.2	-0.3	0.3	-1.7	0.3	-1.5	-0.4	-0.4	-1.3
Ever smoked	0.4	0.6	1.9	-0.6	-0.9	-0.5	0.5	-0.6	0.4	-0.5	-1.4	-1.2
Basal metabolic rate	0.7	4.1	9.5	2.1	-0.5	-1.5	-2.2	-1.0	-1.5	-2.7	-3.1	-2.3
Leg fat percentage (left)	0.5	1.8	5.4	2.3	0.4	-0.6	-1.9	0.3	-2.0	-1.4	0.1	-0.2
Arm fat-free mass (left)	0.8	3.8	10.0	2.0	-0.5	-1.6	-1.9	-0.7	-1.2	-2.6	-3.2	-2.3
Number of operations (self-reported)	1.6	2.4	11.1	0.1	0.5	0.5	1.6	0.4	0.6	1.1	2.5	3.3
Average weekly beer plus cider intake	0.2	0.3	1.5	-0.6	0.7	-0.1	0.4	-1.2	-0.1	0.4	-0.2	0.0
Irritability	0.2	0.3	1.3	-0.6	-0.6	-0.3	0.7	-0.0	1.2	-0.2	-0.5	-0.1
Risk taking	0.4	0.6	3.2	0.3	1.8	0.0	-0.9	-0.5	-0.7	-0.1	0.4	0.7
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.9	0.6	0.2	-0.9	0.5	-0.9	-0.0	-0.4	-0.0	0.4
Fractured/broken bones in last 5 years	0.1	0.1	0.3	-0.1	-0.3	-0.2	-0.5	-0.2	-0.1	-0.0	-0.4	0.1
Age started oral contraceptive pill	0.3	0.4	1.8	1.3	-0.3	-0.8	-0.5	-0.1	-0.3	-0.7	0.3	0.4
Diastolic blood pressure, automated reading	0.8	2.5	4.4	1.8	0.4	-1.5	-2.1	-0.6	-1.3	-2.1	-1.6	-1.7
Ever depressed for a whole week	1.7	2.0	3.9	1.1	1.9	-2.0	-0.6	-1.5	0.0	-1.8	-1.7	-0.8
Unable to work because of sickness or disability	2.3	3.0	7.4	-0.5	2.0	-1.0	2.7	-1.6	2.0	0.5	1.0	2.4
Commuting to job workplace: Cycle	0.4	0.5	2.6	-0.2	-1.0	-0.1	0.9	0.1	1.6	-0.2	-0.0	0.4
Myopia	0.3	0.5	1.3	-0.7	-0.5	1.1	-0.3	0.5	0.1	1.1	0.8	0.6
Vascular/heart problems diagnosed by doctor	0.6	1.6	5.1	-2.2	-0.6	0.8	1.6	0.2	1.9	1.3	0.1	0.6
Cholesterol lowering medication	1.4	2.0	4.9	1.2	0.4	-1.9	-1.0	-2.2	-0.9	-1.4	-1.5	-1.3
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	2.6	1.6	0.6	-1.4	-0.5	-1.0	0.3	-1.4	-0.6	0.4
Pain experienced in last month	1.0	1.7	5.6	0.3	0.0	-0.5	-2.0	0.2	-1.4	-0.8	-1.6	-2.4
Supplements: Calcium	0.4	0.5	1.8	0.0	0.1	-0.3	0.9	-0.6	-0.1	0.4	1.0	1.3
Basal cell carcinoma (self-reported)	2.8	3.3	5.4	1.7	0.8	-2.1	-1.7	-2.0	-2.3	-1.9	-1.7	-1.8
Heart attack/myocardial infarction (self-reported)	0.9	1.2	2.3	-0.9	-0.6	1.5	0.5	1.4	0.2	1.3	1.5	1.1
Deep venous thrombosis (DVT) (self-reported)	2.2	2.8	4.2	-1.3	-1.6	1.2	1.9	2.0	1.5	1.8	1.8	1.8
Heart disease (siblings)	1.7	2.1	4.6	-1.0	-0.4	1.3	1.6	0.8	1.3	1.6	2.1	2.2
Alcohol drinker status: Previous	0.9	1.0	2.9	-1.5	-0.4	0.6	1.7	-0.2	1.2	0.9	0.5	0.9
Pack years of smoking	0.2	0.3	1.3	0.6	1.1	-0.7	0.2	-0.2	0.1	-0.2	0.1	0.5
Impedance of whole body	0.6	2.8	8.3	-0.9	-0.2	1.9	0.9	1.8	0.7	2.2	2.9	1.9
Leg fat mass (left)	0.6	2.3	6.1	2.5	0.3	-0.9	-2.1	-0.1	-2.0	-1.9	-0.9	-0.8
Arm predicted mass (left)	0.6	3.1	8.3	1.7	-0.9	-1.2	-1.9	-0.3	-1.2	-2.2	-2.9	-2.2