TWAS hub - ZNF35

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	YFS	Blood	0.157	0.0354	0.0000	0.063	0.090	0.116	0.117	0.113	8.5e-20	5.5e-28	6.5e-36	2.8e-36	6.7e-35
2	TCGA	Thyroid Carcinoma	0.027	0.0190	0.0017	0.014	0.025	0.009	NA	0.017	1.6e-02	1.5e-03	4.0e-02	NA	8.4e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Seen doctor (GP) for nerves, anxiety, tension or depression	8.5	13.0	22.4	-1.9	4.7
Frequency of tenseness / restlessness in last 2 weeks	7.6	11.7	22.7	-0.9	4.8
Myopia	5.8	8.4	10.2	3.2	-2.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	5.7	6.7	12.5	-0.9	3.5
Osteoarthritis (self-reported)	5.5	7.2	13.2	-3.6	1.1
Frequency of tiredness / lethargy in last 2 weeks	5.3	8.7	16.2	-1.1	4.0
Frequency of depressed mood in last 2 weeks	5.0	7.0	13.1	-1.0	3.6
Mood swings	5.0	9.1	10.3	-3.2	2.8
Depression (self-reported)	4.8	5.7	7.2	-2.0	2.7
Headache pain in last month	4.8	8.3	16.0	-0.8	4.0
Commuting to job workplace: Cycle	4.7	5.7	10.3	1.1	-3.2
Multivitamins +/- minerals	4.6	5.8	6.7	2.6	2.2
Arm fat mass (right)	4.5	18.5	34.3	-5.9	-1.6
Arm fat percentage (left)	4.5	17.8	25.2	-5.0	-3.2
Neuroticism (Nagel 2018)	4.4	10.5	13.0	-2.8	3.6
Taking other prescription medications	4.4	6.8	7.9	-2.8	2.4
Arm fat mass (left)	4.4	17.9	32.5	-5.7	-1.8
Worry (Nagel 2018)	4.3	9.0	14.5	-1.9	3.8
Body mass index (BMI)	4.3	18.4	35.4	-6.0	-1.1
Body Mass Index (BMI) (2010)	4.2	5.7	10.9	-3.3	0.7
Number of live births	4.2	6.0	11.2	-3.3	0.9
Leg fat mass (right)	4.2	16.2	32.4	-5.7	-0.0
Commuting to job workplace: Car/motor vehicle	4.2	4.8	9.0	-3.0	0.7
Supplements: Fish oil (including cod liver oil)	4.2	5.5	10.4	0.8	3.2
Depression (Nagel 2018)	4.1	6.1	11.5	-0.9	3.4
Number of treatments/medications taken	4.1	7.4	7.6	-2.7	2.7
Arm fat percentage (right)	4.1	16.3	25.2	-5.0	-2.7
BMI	4.0	23.2	46.0	-6.8	-0.6
Trunk fat percentage	4.0	16.0	23.3	-4.8	-2.9
Knee pain experienced in last month	4.0	6.3	11.3	-3.4	1.1
Leg fat mass (left)	4.0	15.6	31.2	-5.6	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	3.9	5.0	10.0	-0.1	3.2
Whole body fat mass	3.9	16.4	31.0	-5.6	-1.3
Neuroticism (2016)	3.8	5.5	8.2	-1.6	2.9
Body fat percentage	3.8	15.0	24.9	-5.0	-2.3
Trunk fat mass	3.7	15.8	27.7	-5.3	-2.0
Tense / ‘highly strung’	3.7	6.1	9.7	-1.6	3.1
Leg fat percentage (right)	3.7	13.5	26.9	-5.2	-0.0
Bipolar Disorder (2018)	3.6	5.6	10.4	-0.9	3.2
Chronotype (morning person)	3.6	8.4	15.3	-3.9	1.2
Financial difficulties in last 2 years	3.6	4.9	9.7	0.3	3.1
Back pain experienced in last month	3.6	5.3	10.4	-0.5	3.2
Leg fat percentage (left)	3.6	12.9	25.6	-5.1	-0.3
Hearing difficulty/problems with background noise	3.5	5.6	9.6	3.1	1.2
Alcohol drinker status: Never	3.5	4.2	8.1	-2.8	0.5
Neuroticism	3.4	8.1	9.6	-2.6	3.1
Supplements: Zinc	3.4	3.7	4.9	2.2	1.6
Medication: Metformin	3.4	4.8	8.6	-2.9	-1.0
Intelligence (Savage-Jansen 2018)	3.2	9.7	12.2	2.7	-3.5
Worry too long after embarrassment	3.2	5.4	9.2	-1.3	3.0
Mineral and other dietary supplements	3.2	4.3	8.1	-0.7	-2.8
Waist circumference	3.1	11.4	20.2	-4.5	-1.6
Nervous feelings	3.1	5.8	11.4	0.3	3.4
Neuroticism score	3.0	6.3	7.2	-2.3	2.7
Ulcerative Colitis	2.9	4.2	6.7	1.3	2.6
Impedance of arm (left)	2.9	13.4	13.8	3.6	-3.7
Sensitivity / hurt feelings	2.8	4.8	5.3	-2.3	2.1
Frequency of unenthusiasm / disinterest in last 2 weeks	2.8	3.7	7.3	-0.3	2.7
Weight	2.8	13.9	27.8	-5.3	-0.2
Hip circumference	2.8	12.0	20.9	-4.6	-1.7
Arm fat-free mass (left)	2.8	14.1	21.3	-4.6	2.6
Alzheimer’s Disease (in mother)	2.7	3.1	3.4	1.7	-1.8
Major Depression (MDD)	2.7	3.3	6.7	-0.1	2.6
Type 2 Diabetes (T2D) (2012)	2.7	3.2	4.2	-2.1	-1.4
Ever unenthusiastic/disinterested for a whole week	2.7	3.3	4.9	1.3	2.2
Age at first live birth	2.7	4.8	8.6	2.9	-1.0
Pain type(s) experienced in last month: Hip pain	2.7	3.4	4.5	-2.1	1.5
Qualifications: None of the above	2.6	5.6	11.2	-3.4	-0.2
Angina (self-reported)	2.6	3.4	5.7	-2.4	1.0
Arm predicted mass (right)	2.6	13.3	21.6	-4.7	2.2
Miserableness	2.6	4.6	7.4	-1.3	2.7
Depressed Affect (Nagel 2018)	2.5	5.3	5.4	-2.3	2.3
Maternal smoking around birth	2.5	3.6	6.6	-0.8	-2.6
Worrier / anxious feelings	2.5	4.8	9.5	0.0	3.1
Arm fat-free mass (right)	2.5	12.7	19.2	-4.4	2.5
Medication for pain relief, constipation, heartburn	2.5	4.2	6.5	2.5	-1.4
Guilty feelings	2.5	3.7	5.9	-1.2	2.4
Arm predicted mass (left)	2.5	12.8	19.7	-4.4	2.4
Vitamin and mineral supplements	2.4	3.3	3.7	-1.7	-1.9
Falls in the last year	2.4	3.3	4.2	-1.5	2.0
Medication: Blood pressure	2.4	4.3	5.1	-2.3	1.9
Angina	2.3	3.0	4.7	-2.2	1.1
Commuting to job workplace: Walk	2.3	2.5	4.5	2.1	0.6
Medication: Paracetamol	2.3	3.5	3.8	-1.9	1.8
HbA1C	2.2	2.4	4.5	-0.6	-2.1
Impedance of arm (right)	2.2	10.1	13.5	3.7	-2.6
Medication: Omeprazole	2.2	2.7	4.6	-2.1	0.9
Vascular/heart problems diagnosed by doctor	2.2	6.0	10.8	3.3	-1.1
Hearing difficulty/problems: Yes	2.1	3.1	4.8	2.2	-1.2
Age when periods started (menarche)	2.1	5.1	8.5	1.3	-2.9
Alcohol intake versus 10 years previously	2.1	3.1	6.1	0.4	-2.5
Serious illness, injury or assault of a close relative in last 2 years	2.1	2.4	4.6	-0.4	-2.1
Pain experienced in last month	2.1	3.5	4.4	2.1	-1.6
Reaction Time	2.0	3.8	7.3	-2.7	0.6
Heart attack	2.0	2.5	5.0	-2.2	0.0
Suffer from ‘nerves’	2.0	3.2	5.0	-1.2	2.2
Average weekly red wine intake	2.0	3.0	6.0	2.4	0.1
Medication: Omeprazole (e.g. Zanprol)	2.0	2.4	4.0	-2.0	0.8
Heart attack/myocardial infarction (self-reported)	2.0	2.6	5.2	-2.3	-0.3
Hypothyroidism (self reported)	1.9	4.3	8.1	-2.9	-0.7
Mouth/teeth dental problems: Dentures	1.9	3.2	6.4	-2.5	0.2
Medication for cholesterol, blood pressure or diabetes	1.9	3.1	5.1	2.2	-1.1
Hypertension (Self-reported)	1.9	5.2	10.2	-3.2	0.3
Long-standing illness, disability or infirmity	1.9	3.0	3.0	-1.7	1.7
Financial situation satisfaction	1.9	2.4	3.5	1.1	1.9
Schizophrenia vs Biploar Disorder	1.8	2.4	3.5	1.1	-1.9
Medication: Allopurinol	1.8	2.5	3.7	-1.1	1.9
Had major operations	1.8	2.1	3.9	2.0	0.6
Qualifications: nursing, teaching	1.8	2.8	5.3	-0.5	2.3
Basal metabolic rate	1.8	9.9	18.8	-4.3	1.0
High blood pressure	1.7	4.7	8.9	-3.0	0.7
Medication: Paracetamol	1.7	2.9	3.7	-1.4	1.9
Age at last live birth	1.7	2.4	2.7	1.5	-1.6
Leg pain on walking	1.7	2.1	4.2	-2.0	0.3
Diabetes diagnosed by doctor	1.7	2.9	5.4	-2.3	-0.6
Wears glasses or contact lenses	1.7	1.9	3.8	-0.2	-2.0
Age at First Birth	1.6	2.3	3.8	0.9	-2.0
Lung FVC	1.6	8.1	15.2	3.9	1.0
Pack years adult smoking proportion	1.6	2.4	4.4	-0.7	2.1
Supplements: Glucosamine	1.6	2.1	3.8	0.5	2.0
Trunk predicted mass	1.6	9.0	11.7	-3.4	2.5
Mean time to correctly identify matches	1.6	3.0	5.9	-2.4	-0.3
Whole body water mass	1.6	9.2	15.9	-4.0	1.6
HDL Cholesterol	1.5	2.5	5.0	2.2	-0.3
Fed-up feelings	1.5	2.7	5.2	-2.3	0.6
Trunk fat-free mass	1.5	8.8	11.6	-3.4	2.5
Hypothyroidism/myxoedema (self-reported)	1.5	3.0	4.2	-2.0	-1.3
Whole body fat-free mass	1.5	8.5	15.1	-3.9	1.4
Number of self-reported non-cancer illnesses	1.5	2.7	3.7	-1.9	1.3
Fasting Glucose	1.4	1.6	2.9	-0.6	1.7
Rheumatoid Arthritis	1.4	2.0	3.5	-1.9	-0.7
Triglycerides	1.4	2.3	3.2	-1.8	-1.2
Medication for hormone replacement therapy	1.4	1.6	1.7	-1.2	1.3
Leg fat-free mass (left)	1.4	7.6	15.2	-3.9	-0.4
Medication: Levothyroxine sodium	1.4	2.4	4.3	-2.1	-0.7
Leg predicted mass (left)	1.4	7.5	14.7	-3.8	-0.4
Hair/balding pattern: Pattern 2	1.4	1.7	2.9	-1.7	-0.7
Hair/balding pattern: Pattern 3	1.4	2.0	4.0	2.0	0.2
Mouth/teeth dental problems: Bleeding gums	1.4	1.8	3.1	0.7	-1.8
Chronic bronchitis/emphysema (mother)	1.4	1.7	3.2	-1.8	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.7	2.8	-0.7	-1.7
Ever depressed for a whole week	1.4	1.7	2.4	1.0	1.6
Type 2 Diabetes (T2D) (2018)	1.3	2.4	4.4	-2.1	-0.6
Lung FEV1/FVC ratio	1.3	6.8	11.0	-1.6	-3.3
Medication: Co-codamol	1.3	1.5	2.0	-1.0	1.4
Number of full brothers	1.3	1.7	2.9	-0.7	-1.7
Illnesses of siblings: Diabetes	1.3	1.6	2.8	-1.7	-0.6
Medication: Gliclazide	1.3	1.4	2.5	-0.6	-1.6
Mother’s age at death	1.3	1.7	3.2	1.8	0.3
Alcohol drinker status: Previous	1.3	1.4	2.1	-0.9	-1.4
Breast Cancer	1.2	2.9	3.8	-1.4	2.0
Impedance of leg (right)	1.2	5.7	7.1	2.1	2.7
Qualifications: CSEs or equivalent	1.2	1.5	2.6	-0.6	1.6
Leg fat-free mass (right)	1.2	6.4	12.3	-3.5	-0.7
Eye problems/disorders: Cataract	1.2	1.4	2.6	-0.4	-1.6
Leg predicted mass (right)	1.2	6.5	12.5	-3.5	-0.7
Average weekly champagne plus white wine intake	1.2	1.6	2.9	1.7	-0.6
Tinnitus: Yes, now most or all of the time	1.2	1.4	2.8	-1.7	0.2
Unable to work because of sickness or disability	1.2	1.6	2.1	-1.4	1.0
Other serious medical condition/disability diagnosed by doctor	1.1	1.4	2.7	0.4	1.6
Diabetes (father)	1.1	1.3	2.2	0.6	-1.5
Sitting height	1.1	7.7	12.2	-1.8	3.5
Impedance of leg (left)	1.1	5.4	6.2	2.1	2.5
Diabetes (self-reported)	1.1	1.7	2.7	-1.7	-0.9
Loud music exposure frequency	1.1	1.2	2.4	-0.2	1.6
Birth weight	1.1	2.3	3.0	1.7	-1.3
Pulse wave peak to peak time	1.1	1.3	2.0	0.7	1.4
Emphysema/chronic bronchitis	1.1	1.3	2.2	-1.5	0.6
Commuting to job workplace: Public transport	1.1	1.3	2.6	1.6	-0.2
Impedance of whole body	1.1	5.7	10.6	3.2	-0.9
Primary Biliary Cirrhosis	1.0	1.5	1.7	-1.3	-1.1
Noisy workplace	1.0	1.2	2.1	-0.5	-1.5
Breastfed as a baby	1.0	1.2	2.5	1.6	0.1
Medication: Ventolin 100micrograms inhaler	1.0	1.2	2.4	-1.6	-0.3
Medication: Ibuprofen	1.0	1.2	2.1	-1.4	-0.5
Ever had bowel cancer screening	1.0	1.2	2.1	1.4	0.5
Bipolar Disorder (2011)	0.9	0.9	1.1	-0.8	1.0
Systolic blood pressure, automated reading	0.9	2.5	5.1	-2.3	-0.1
Townsend deprivation index at recruitment	0.9	1.2	2.2	0.5	1.5
Serious illness, injury or assault to yourself	0.9	1.1	1.6	-1.3	-0.8
Allergy	0.9	2.0	3.0	1.7	-1.0
Pulse wave Arterial Stiffness index	0.9	1.0	1.3	-0.9	-1.1
Blood clot in the leg (DVT)	0.9	1.1	1.2	-1.0	1.1
Mouth/teeth dental problems: Loose teeth	0.9	1.1	1.8	1.3	-0.6
Supplements: Vitamin C	0.9	1.1	1.7	0.6	1.3
Asthma (self-reported)	0.9	1.7	3.5	-1.9	-0.2
Pack years of smoking	0.9	1.4	2.6	-0.3	1.6
Bipolar Disorder or Schizophrenia	0.8	2.0	3.8	0.4	2.0
Alzheimer’s Disease (including proxy)	0.8	1.2	1.7	1.3	-0.9
Prostate Cancer	0.8	1.1	1.9	-1.4	0.5
Coronary Artery Disease (CAD)	0.8	0.9	1.8	0.0	1.4
Cardiovascular Disease	0.8	2.6	5.1	-2.3	-0.0
Stomach or abdominal pain in last month	0.8	1.0	1.4	-0.7	1.2
Pain all over the body in last month	0.8	0.9	1.6	-1.3	-0.3
Father’s age at death	0.8	1.1	1.8	1.3	-0.6
Medication: Cholesterol lowering	0.8	1.3	1.5	-1.1	1.2
Gout (self-reported)	0.8	1.1	1.7	-0.7	1.3
Medication: Amlodipine	0.8	1.1	1.5	-1.2	0.9
Qualifications: College or University degree	0.8	2.6	4.3	2.1	-0.9
Alcohol intake frequency.	0.8	1.9	2.8	-1.7	-1.0
Overall health rating	0.8	1.7	2.4	-1.6	1.0
Medication: Aspirin	0.8	1.1	1.4	-1.2	0.9
Medication: Lisinopril	0.8	1.0	1.3	-1.1	-0.8
Deep venous thrombosis (DVT) (self-reported)	0.8	1.1	1.3	-1.1	0.9
Verbal and Numeric Reasoning (VNR)	0.7	1.7	3.1	1.8	-0.5
Blood Red Count	0.7	6.5	12.4	-3.5	-0.7
Average weekly spirits intake	0.7	0.9	1.6	-1.2	0.4
Qualifications: A levels/AS levels or equivalent	0.7	1.6	3.1	1.8	-0.1
Asthma	0.7	1.4	2.7	-1.6	-0.2
Length of working week for main job	0.7	0.7	1.4	-1.2	0.0
Smoking status: Previous	0.7	1.0	1.9	1.4	-0.2
Illnesses of father: High blood pressure	0.7	0.8	1.6	-1.2	0.3
LDL Cholesterol	0.6	1.0	1.9	-0.1	-1.4
Ever had hysterectomy (womb removed)	0.6	0.6	1.1	-1.0	0.5
Hand grip strength (right)	0.6	1.6	3.2	-0.2	1.8
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	1.5	-1.0	1.2
Hayfever, allergic rhinitis or eczema	0.6	1.2	1.4	-1.0	1.2
Chronic bronchitis/emphysema (father)	0.6	0.7	1.4	-1.2	-0.4
High blood pressure (mother)	0.6	0.8	1.5	-0.3	1.2
Past tobacco smoking	0.6	1.2	1.7	-1.3	0.8
Fluid intelligence score	0.6	1.2	2.4	1.5	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	1.1	-0.7	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.6	1.2	0.3	1.1
Health satisfaction	0.6	0.8	1.3	-0.4	1.2
Medication: Blood pressure	0.6	1.1	2.2	-1.5	0.2
Basal cell carcinoma (self-reported)	0.6	0.7	1.4	1.2	0.0
Schizophrenia (2014)	0.5	1.1	2.1	1.4	-0.3
Heel T-Score	0.5	4.1	8.1	-0.3	2.8
Bilateral oophorectomy (both ovaries removed)	0.5	0.5	1.0	0.2	-1.0
Number of incorrect matches in round	0.5	0.9	1.6	-1.2	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.0	1.1	-1.1	1.0
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	1.3	-0.3	1.2
Time employed in main current job	0.5	0.6	1.1	0.4	-1.0
Medication: Seretide 50 evohaler	0.5	0.5	0.6	-0.7	0.8
Medication: Aspirin	0.5	0.6	0.7	-0.7	0.8
Illnesses of father: Heart disease	0.5	0.7	1.1	-0.5	-1.1
Handedness (chirality/laterality): Left-handed	0.5	0.7	1.1	1.1	0.4
Friendships satisfaction	0.5	0.6	1.3	0.1	-1.1
Osteoporosis (self-reported)	0.5	0.6	1.1	-0.3	-1.0
Schizophrenia (2018)	0.4	0.8	1.6	1.3	-0.1
Respiratory disease	0.4	0.8	1.6	-1.3	0.2
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	0.9	-0.9	0.1
Severe depression (siblings)	0.4	0.5	1.0	-1.0	0.1
Alcohol usually taken with meals	0.4	0.7	1.4	-0.2	-1.2
Mouth/teeth dental problems	0.4	0.6	1.0	0.4	1.0
Exposure to tobacco smoke at home	0.4	0.4	0.5	0.6	-0.7
Birth weight of first child	0.4	0.7	1.3	0.4	1.1
Forced vital capacity (FVC), Best measure	0.4	1.5	2.2	1.5	0.9
Wheeze or whistling in the chest in last year	0.4	0.8	1.5	-1.2	0.1
Number of full sisters	0.4	0.5	1.1	-0.0	1.0
Ever smoked	0.4	0.8	1.6	1.2	0.1
Number of operations (self-reported)	0.4	0.7	0.9	0.6	0.9
Risk taking	0.4	0.6	1.1	-0.2	-1.1
Ever had prostate specific antigen (PSA) test	0.4	0.5	0.9	1.0	-0.3
Fractured/broken bones in last 5 years	0.4	0.6	1.0	0.3	-1.0
Alzheimer’s Disease (in father)	0.3	0.3	0.7	0.8	-0.0
Mean Putamen Volume	0.3	0.3	0.3	-0.6	0.5
Lupus	0.3	0.4	0.4	-0.6	-0.6
Blood Platelet Count	0.3	3.6	6.6	-0.8	2.6
Blood White Count	0.3	1.9	3.8	-1.9	0.3
Smoking Status	0.3	0.8	1.1	1.0	0.8
Relative age voice broke	0.3	0.5	0.9	-0.9	-0.1
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.5	0.7	-0.4
Had menopause	0.3	0.3	0.5	-0.4	0.7
Illnesses of siblings	0.3	0.5	0.9	1.0	0.0
Pulse rate	0.3	0.6	1.1	1.1	0.0
Lung cancer (father)	0.3	0.4	0.8	0.1	-0.9
Glaucoma (self-reported)	0.3	0.4	0.4	0.6	-0.7
Eye problems/disorders: None of the above	0.3	0.4	0.6	0.5	0.7
Heart disease (mother)	0.3	0.3	0.7	-0.2	-0.8
Pulse rate, automated reading	0.3	1.0	1.7	-1.3	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	0.3	-0.5	-0.6
Loneliness, isolation	0.3	0.4	0.8	-0.9	0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.1	0.3	-1.1
Ever taken oral contraceptive pill	0.3	0.3	0.5	-0.7	0.4
Eye problems/disorders: Glaucoma	0.3	0.3	0.5	0.4	0.7
Medication: Bendroflumethiazide	0.3	0.4	0.5	-0.6	0.7
Medication: Atorvastatin	0.3	0.4	0.8	0.0	0.9
Diastolic blood pressure, automated reading	0.3	1.0	2.0	-1.4	0.2
Ulcerative Colitis (UC)	0.2	0.4	0.7	0.8	0.0
Systolic Blood Pressure	0.2	1.2	2.5	-1.6	-0.1
Allergy or Eczema	0.2	0.5	0.9	-0.4	0.9
Hand grip strength (left)	0.2	0.6	1.2	0.1	1.1
Relative age of first facial hair	0.2	0.3	0.5	0.7	-0.5
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.5	-0.7	0.2
Average weekly fortified wine intake	0.2	0.2	0.3	0.5	0.4
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.4	0.6	-0.2
Forced vital capacity (FVC)	0.2	0.9	1.0	1.0	0.9
Medication: Lansoprazole	0.2	0.3	0.5	-0.1	-0.7
Prospective memory result	0.2	0.2	0.4	0.1	0.6
Standing height	0.2	2.0	3.8	0.4	1.9
Hair/balding pattern: Pattern 4	0.2	0.6	1.1	1.1	0.0
High blood pressure (siblings)	0.2	0.3	0.7	-0.8	-0.2
Shortness of breath walking on level ground	0.2	0.2	0.3	-0.5	0.4
Neck or shoulder pain in last month	0.2	0.3	0.4	-0.7	0.4
Comparative height size at age 10	0.2	1.2	2.0	0.5	1.4
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.4	-0.6	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	0.9	-0.3	1.0
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.3	0.5	0.5
Medication for cholesterol	0.2	0.4	0.5	0.7	-0.5
Breast cancer (self-reported)	0.2	0.3	0.4	0.4	0.7
High cholesterol (Self-reported)	0.2	0.3	0.5	0.7	-0.0
Age started oral contraceptive pill	0.2	0.3	0.5	0.7	-0.1
Cholesterol lowering medication	0.2	0.3	0.7	0.8	-0.1
Supplements: Calcium	0.2	0.2	0.2	0.4	-0.4
Crohns Disease (2017)	0.1	0.3	0.4	-0.7	0.5
Irritable Bowel Disease (IBD)	0.1	0.2	0.4	0.1	0.7
Ovarian Cancer	0.1	0.1	0.2	-0.1	0.4
Height	0.1	1.3	1.9	1.4	0.8
Waist Hip Ratio (WHR)	0.1	0.6	1.0	0.5	1.0
Hair Pigment	0.1	1.5	1.7	-1.1	1.3
Tanning	0.1	1.5	2.9	-0.3	-1.7
Current tobacco smoking	0.1	0.2	0.3	-0.5	0.2
Medication: Atenolol	0.1	0.1	0.2	-0.3	-0.5
Had other major operations	0.1	0.1	0.2	0.2	-0.4
Peak expiratory flow (PEF)	0.1	0.2	0.4	-0.2	-0.6
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.1	-0.3	0.3
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.1	-0.4	0.2
Exposure to tobacco smoke outside home	0.1	0.1	0.3	0.1	-0.5
Comparative body size at age 10	0.1	0.3	0.5	-0.2	0.7
Number of children fathered	0.1	0.1	0.1	0.3	0.4
Migraine (self-reported)	0.1	0.1	0.2	0.4	0.1
Chest pain or discomfort	0.1	0.2	0.3	-0.6	-0.3
Family relationship satisfaction	0.1	0.1	0.2	0.4	-0.0
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.2	0.4	-0.1
Illnesses of father: None of the above (group 1)	0.1	0.1	0.2	0.4	-0.2
Smoking status: Current	0.1	0.2	0.3	-0.6	0.3
Hearing aid user	0.1	0.1	0.1	0.3	-0.2
Average weekly beer plus cider intake	0.1	0.2	0.3	-0.1	-0.6
Irritability	0.1	0.2	0.3	-0.6	0.1
Crohns Disease (2012)	0.0	0.0	0.0	-0.1	0.2
Blood Eosinophil Count	0.0	0.1	0.2	-0.1	-0.5
Diabetes (mother)	0.0	0.0	0.1	0.3	-0.1
Medication: Ramipril	0.0	0.0	0.0	-0.2	-0.1
Medication: Simvastatin	0.0	0.0	0.1	-0.0	-0.2
Forced expiratory volume in 1-second (FEV1)	0.0	0.0	0.0	-0.2	0.2
Happiness	0.0	0.0	0.0	0.1	0.1
Illnesses of mother	0.0	0.0	0.0	-0.0	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.1	0.2	0.5	0.1
Pulse wave reflection index	0.0	0.0	0.0	-0.2	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.0	0.0	0.0	0.2	0.1
Heart disease (siblings)	0.0	0.0	0.0	-0.2	0.1

Hub : Genes

ZNF35

Models

Trait associations