TWAS hub - ZNF440

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Cells Transformed fibroblasts	0.1570	0.0520	4.1e-05	0.066	NA	0.136	NA	0.111	1.1e-05	NA	2.4e-10	NA	1.2e-08
2	TCGA	Breast Invasive Carcinoma	0.0488	0.0333	1.9e-04	0.025	0.022	0.007	NA	0.023	6.1e-06	1.9e-05	9.7e-03	NA	1.3e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Alzheimer’s Disease (in father)	7.1	7.7	11.0	2.1	-3.3
Supplements: Zinc	5.4	5.9	7.5	2.1	-2.7
Blood White Count	5.2	38.5	46.1	5.5	-6.8
Relative age voice broke	5.0	7.7	9.6	-3.1	2.4
Medication: Gliclazide	4.7	5.4	7.0	2.6	-1.9
Length of working week for main job	4.4	4.8	6.8	1.7	-2.6
Heart attack	4.1	5.2	7.6	2.8	-1.7
Heart attack/myocardial infarction (self-reported)	3.5	4.6	6.5	2.5	-1.6
Depression (Nagel 2018)	3.3	5.0	5.2	2.3	-2.2
Frequency of unenthusiasm / disinterest in last 2 weeks	3.3	4.4	5.3	1.9	-2.3
Knee pain experienced in last month	3.3	5.1	5.8	2.1	-2.4
Heart disease (siblings)	3.0	3.7	5.5	-1.4	2.3
LDL Cholesterol	2.9	4.7	5.3	-2.0	2.3
Breastfed as a baby	2.9	3.6	4.0	1.8	-2.0
Medication: Simvastatin	2.8	4.1	7.2	2.7	-1.0
Frequency of depressed mood in last 2 weeks	2.6	3.6	4.4	2.1	-1.7
Diabetes (mother)	2.6	3.4	3.4	1.8	-1.8
Blood Eosinophil Count	2.5	19.2	19.2	4.4	-4.4
Illnesses of mother	2.5	3.1	5.2	-2.3	1.0
Pulse wave reflection index	2.5	3.1	3.6	1.6	-1.9
Long-standing illness, disability or infirmity	2.4	3.6	3.9	1.8	-2.0
Number of treatments/medications taken	2.3	4.1	4.8	2.2	-1.8
Leg pain on walking	2.3	2.9	3.4	1.9	-1.6
Commuting to job workplace: Cycle	2.3	2.8	2.9	-1.6	1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	2.1	2.8	4.2	2.0	-1.2
Osteoarthritis (self-reported)	2.1	2.7	3.6	1.9	-1.3
Number of operations (self-reported)	2.1	3.1	4.0	1.5	-2.0
Alcohol drinker status: Previous	2.1	2.4	2.8	-1.7	1.4
Hip circumference	2.0	8.7	10.5	3.2	-2.6
Eye problems/disorders: None of the above	2.0	2.4	2.5	-1.6	1.5
Lung cancer (father)	1.9	2.2	3.1	1.1	-1.8
Deep venous thrombosis (DVT) (self-reported)	1.8	2.3	2.6	1.6	-1.4
Relative age of first facial hair	1.7	3.5	5.3	-2.3	1.3
Illness, injury, bereavement, stress in last 2 years	1.7	2.1	2.1	-1.5	1.5
Hearing aid user	1.7	1.9	2.0	1.3	-1.4
Lung FEV1/FVC ratio	1.6	8.2	9.1	2.7	-3.0
Body mass index (BMI)	1.6	7.0	9.7	3.1	-2.1
Loud music exposure frequency	1.6	1.7	1.7	-1.3	1.3
Suffer from ‘nerves’	1.6	2.5	4.5	-2.1	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.9	2.5	1.2	-1.6
Breast cancer (self-reported)	1.6	1.9	2.7	1.6	-1.1
Had other major operations	1.5	1.9	2.2	1.2	-1.5
Alcohol intake versus 10 years previously	1.5	2.2	2.2	1.5	-1.5
Ovarian Cancer	1.4	1.8	2.9	1.7	-0.8
BMI	1.4	7.9	11.4	3.4	-2.1
Multivitamins +/- minerals	1.4	1.8	2.5	1.0	-1.6
Had menopause	1.4	1.8	2.0	-1.4	1.3
Comparative body size at age 10	1.4	3.9	4.5	-1.8	2.1
Leg fat percentage (left)	1.4	5.1	6.2	2.5	-2.0
Risk taking	1.4	2.0	2.5	1.6	-1.3
Schizophrenia vs Biploar Disorder	1.3	1.8	2.1	1.2	-1.4
Major Depression (MDD)	1.3	1.5	1.5	1.2	-1.2
Blood clot in the leg (DVT)	1.3	1.7	1.8	1.3	-1.2
Leg fat mass (right)	1.3	4.9	6.7	2.6	-1.7
Average weekly champagne plus white wine intake	1.3	1.8	2.0	-1.3	1.4
Leg fat mass (left)	1.3	5.1	7.0	2.6	-1.8
Bipolar Disorder (2018)	1.2	1.8	2.8	-0.9	1.7
Irritable Bowel Disease (IBD)	1.2	2.8	3.1	1.6	-1.8
Triglycerides	1.2	1.9	2.0	-1.4	1.4
Ever used hormone-replacement therapy (HRT)	1.2	1.5	1.9	1.1	-1.4
Systolic blood pressure, automated reading	1.2	3.6	4.7	1.6	-2.2
Waist circumference	1.2	4.4	5.9	2.4	-1.7
Arm fat percentage (right)	1.2	4.7	6.0	2.5	-1.8
Hair/balding pattern: Pattern 3	1.2	1.8	2.0	1.3	-1.4
Chronic bronchitis/emphysema (mother)	1.2	1.3	2.3	1.5	-0.6
Leg fat percentage (right)	1.2	4.2	4.9	2.2	-1.9
Illnesses of father: None of the above (group 1)	1.2	1.4	1.5	-1.2	1.2
Sensitivity / hurt feelings	1.1	1.9	2.6	-1.6	1.1
Pack years adult smoking proportion	1.1	1.7	2.6	0.8	-1.6
Hand grip strength (right)	1.1	2.9	3.1	-1.7	1.8
Nervous feelings	1.1	2.1	3.8	0.7	-1.9
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	1.4	1.2	-1.2
Pulse wave Arterial Stiffness index	1.1	1.3	1.4	1.2	-1.1
Arm fat mass (right)	1.1	4.7	6.7	2.6	-1.7
Forced vital capacity (FVC), Best measure	1.1	4.1	4.8	-2.2	1.8
Arm fat percentage (left)	1.1	4.3	6.1	2.5	-1.6
Arm fat mass (left)	1.1	4.4	6.4	2.5	-1.6
Pain experienced in last month	1.1	1.8	1.9	-1.3	1.4
Pack years of smoking	1.1	1.7	2.6	0.8	-1.6
Depressed Affect (Nagel 2018)	1.0	2.2	3.2	1.1	-1.8
Crohns Disease (2017)	1.0	2.2	4.0	0.6	-2.0
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.2	4.3	0.4	-2.1
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	2.1	1.5	-0.6
Body fat percentage	1.0	3.9	4.8	2.2	-1.7
Pulse wave peak to peak time	1.0	1.2	1.2	-1.1	1.1
Irritability	1.0	1.7	2.3	1.0	-1.5
Ever depressed for a whole week	1.0	1.2	1.8	-0.8	1.4
Schizophrenia (2018)	0.9	1.8	2.4	1.6	-1.1
Ulcerative Colitis (UC)	0.9	1.6	2.7	1.6	-0.8
Average weekly spirits intake	0.9	1.1	1.3	-1.1	0.9
Medication: Metformin	0.9	1.3	2.4	1.6	-0.5
Weight	0.9	4.4	6.6	2.6	-1.5
Impedance of arm (left)	0.9	4.1	5.5	-2.3	1.7
Whole body fat mass	0.9	3.9	5.6	2.4	-1.5
Handedness (chirality/laterality): Left-handed	0.9	1.1	1.2	1.0	-1.1
Eye problems/disorders: Cataract	0.9	1.0	1.2	0.9	-1.1
Commuting to job workplace: Public transport	0.9	1.1	1.3	-1.2	1.0
Basal cell carcinoma (self-reported)	0.9	1.0	1.6	0.7	-1.3
Neuroticism (Nagel 2018)	0.8	1.9	3.2	0.7	-1.8
Prostate Cancer	0.8	1.2	1.4	-1.0	1.2
Hearing difficulty/problems: Yes	0.8	1.2	1.5	0.9	-1.2
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	1.0	1.0	-0.9
Serious illness, injury or assault of a close relative in last 2 years	0.8	1.0	1.3	0.8	-1.1
Medication: Lansoprazole	0.8	0.9	1.3	1.2	-0.7
Prospective memory result	0.8	1.0	1.6	1.3	-0.6
Commuting to job workplace: Car/motor vehicle	0.8	0.9	0.9	0.9	-1.0
Supplements: Vitamin C	0.8	0.9	1.1	-1.1	0.8
Diabetes diagnosed by doctor	0.8	1.4	2.5	1.6	-0.6
Supplements: Fish oil (including cod liver oil)	0.8	1.0	1.1	-1.1	0.9
Impedance of whole body	0.8	3.9	6.5	-2.5	1.2
HbA1C	0.7	0.8	0.9	-0.8	1.0
Type 2 Diabetes (T2D) (2012)	0.7	0.9	1.2	-0.7	1.1
Waist Hip Ratio (WHR)	0.7	3.0	4.2	-2.1	1.3
Smoking Status	0.7	1.6	1.9	-1.1	1.4
Lung FVC	0.7	3.5	5.4	-2.3	1.3
Vitamin and mineral supplements	0.7	1.0	1.9	-0.4	1.4
Impedance of leg (right)	0.7	3.5	6.5	-2.5	0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.7	3.4	-0.1	-1.8
Trunk fat mass	0.7	2.9	4.0	2.0	-1.4
Forced vital capacity (FVC)	0.7	2.7	2.8	-1.7	1.6
Pain all over the body in last month	0.7	0.8	1.2	1.1	-0.6
Illnesses of siblings	0.7	1.0	1.4	0.8	-1.2
Number of live births	0.7	1.0	1.7	1.3	-0.6
Medication: Cholesterol lowering	0.7	1.2	2.2	1.5	0.3
Medication: Bendroflumethiazide	0.7	1.0	1.2	-0.9	1.1
Illnesses of father: High blood pressure	0.7	0.9	1.3	1.1	-0.7
Vascular/heart problems diagnosed by doctor	0.7	1.8	3.0	-1.7	0.7
Bipolar Disorder (2011)	0.6	0.6	1.1	0.0	1.1
Schizophrenia (2014)	0.6	1.4	2.0	1.4	-0.9
Medication: Levothyroxine sodium	0.6	1.0	1.5	-0.7	1.2
Impedance of leg (left)	0.6	2.9	5.2	-2.3	0.7
Hearing difficulty/problems with background noise	0.6	0.9	1.4	0.6	-1.2
Impedance of arm (right)	0.6	2.8	4.8	-2.2	0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.9	2.6	-1.6	1.1
Mouth/teeth dental problems: Loose teeth	0.6	0.7	1.3	0.2	-1.2
Emphysema/chronic bronchitis	0.6	0.7	1.1	1.1	-0.5
Pulse rate, automated reading	0.6	1.9	2.6	1.1	-1.6
Alcohol intake frequency.	0.6	1.3	1.3	1.1	-1.1
Medication: Lisinopril	0.6	0.8	1.2	0.6	-1.1
Alcohol drinker status: Never	0.6	0.7	1.1	0.5	-1.1
Arm fat-free mass (left)	0.6	2.9	4.1	2.0	-1.3
Cholesterol lowering medication	0.6	0.9	1.4	1.2	-0.7
Alzheimer’s Disease (including proxy)	0.5	0.7	1.3	0.2	-1.1
Age at First Birth	0.5	0.8	1.2	1.1	-0.6
Coronary Artery Disease (CAD)	0.5	0.6	0.8	0.9	-0.7
Blood Red Count	0.5	4.6	5.9	2.4	-1.8
Systolic Blood Pressure	0.5	2.6	3.3	1.4	-1.8
Hand grip strength (left)	0.5	1.4	2.0	-0.9	1.4
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	1.0	-0.5	1.0
Trunk fat percentage	0.5	2.0	2.4	1.5	-1.2
Taking other prescription medications	0.5	0.8	1.5	1.2	-0.2
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	0.7	0.9	-0.6
High blood pressure (mother)	0.5	0.7	1.1	1.1	-0.5
Leg predicted mass (left)	0.5	2.4	4.2	2.1	-0.8
Past tobacco smoking	0.5	0.9	1.4	0.6	-1.2
Pulse rate	0.5	0.8	1.4	-1.2	0.5
Arm fat-free mass (right)	0.5	2.3	3.8	1.9	-0.9
Exposure to tobacco smoke outside home	0.5	0.7	1.3	-0.2	1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.5	1.0	1.0	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.2	-1.1	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.1	1.0	-0.4
Illnesses of father: Heart disease	0.5	0.6	1.0	1.0	-0.6
Smoking status: Previous	0.5	0.7	1.3	-0.4	1.1
Leg fat-free mass (right)	0.5	2.5	4.4	2.1	-0.8
Basal metabolic rate	0.5	2.7	4.4	2.1	-1.0
Average weekly beer plus cider intake	0.5	0.7	1.5	0.1	1.2
Fractured/broken bones in last 5 years	0.5	0.6	0.8	0.6	-0.9
Arm predicted mass (left)	0.5	2.6	3.9	2.0	-1.2
Alzheimer’s Disease (in mother)	0.4	0.5	0.5	-0.7	0.6
Ever had hysterectomy (womb removed)	0.4	0.4	0.7	-0.4	0.8
Leg fat-free mass (left)	0.4	2.3	4.1	2.0	-0.7
Average weekly fortified wine intake	0.4	0.5	0.9	0.3	-1.0
Age when periods started (menarche)	0.4	0.9	1.4	0.7	-1.2
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	0.6	0.8	-0.6
Financial difficulties in last 2 years	0.4	0.5	0.5	0.7	-0.7
Mouth/teeth dental problems	0.4	0.6	1.0	-0.5	1.0
Medication: Ramipril	0.4	0.6	1.1	1.1	-0.1
Time employed in main current job	0.4	0.4	0.8	-0.0	0.9
Qualifications: A levels/AS levels or equivalent	0.4	0.8	1.4	0.5	-1.2
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	1.1	-1.0	-0.6
Wheeze or whistling in the chest in last year	0.4	0.8	1.0	1.0	-0.7
Number of children fathered	0.4	0.4	0.6	0.5	-0.8
Medication: Blood pressure	0.4	0.6	1.3	1.1	0.2
Arm predicted mass (right)	0.4	1.9	3.3	1.8	-0.8
Whole body fat-free mass	0.4	2.2	3.7	1.9	-0.9
Mineral and other dietary supplements	0.4	0.5	0.9	1.0	-0.3
Leg predicted mass (right)	0.4	2.3	4.2	2.0	-0.7
Ever taken oral contraceptive pill	0.4	0.4	0.5	0.7	-0.5
Pain type(s) experienced in last month: Hip pain	0.4	0.5	0.8	0.5	-0.9
Diastolic blood pressure, automated reading	0.4	1.3	1.7	0.9	-1.3
Intelligence (Savage-Jansen 2018)	0.3	0.8	1.4	1.2	-0.4
Reaction Time	0.3	0.5	0.5	-0.7	0.7
Crohns Disease (2012)	0.3	0.5	1.0	-0.3	-1.0
Ulcerative Colitis	0.3	0.5	0.9	0.9	-0.3
Allergy or Eczema	0.3	0.9	1.1	-1.0	0.8
Type 2 Diabetes (T2D) (2018)	0.3	0.5	0.8	0.9	0.4
Neuroticism	0.3	0.6	1.2	-0.0	-1.1
Maternal smoking around birth	0.3	0.4	0.6	0.8	-0.4
High blood pressure	0.3	1.0	1.8	1.3	-0.3
Supplements: Glucosamine	0.3	0.4	0.9	0.1	-0.9
Hair/balding pattern: Pattern 2	0.3	0.3	0.7	-0.8	0.1
Trunk fat-free mass	0.3	1.5	2.5	1.6	-0.7
Noisy workplace	0.3	0.4	0.5	0.7	-0.5
Tense / ‘highly strung’	0.3	0.5	1.1	-1.0	0.2
Medication: Paracetamol	0.3	0.5	0.8	-0.9	0.4
Headache pain in last month	0.3	0.5	0.8	0.5	-0.9
Worry too long after embarrassment	0.3	0.4	0.6	-0.5	-0.8
Heart disease (mother)	0.3	0.4	0.7	0.8	0.1
Family relationship satisfaction	0.3	0.4	0.7	0.3	-0.8
Mood swings	0.3	0.6	0.7	0.7	-0.8
Friendships satisfaction	0.3	0.4	0.5	0.7	-0.6
Commuting to job workplace: Walk	0.3	0.3	0.6	-0.8	0.2
Whole body water mass	0.3	1.9	3.2	1.8	-0.7
High cholesterol (Self-reported)	0.3	0.6	0.7	0.7	0.8
Ever smoked	0.3	0.6	0.8	-0.6	0.9
Supplements: Calcium	0.3	0.4	0.6	0.4	-0.8
Worry (Nagel 2018)	0.2	0.5	0.9	-0.2	-0.9
Fasting Glucose	0.2	0.3	0.3	0.5	-0.6
Neuroticism (2016)	0.2	0.2	0.5	0.1	-0.7
Primary Biliary Cirrhosis	0.2	0.3	0.5	-0.7	-0.2
Diabetes (father)	0.2	0.2	0.5	-0.0	0.7
Qualifications: CSEs or equivalent	0.2	0.3	0.5	-0.7	0.1
Diabetes (self-reported)	0.2	0.2	0.5	0.7	0.1
Fluid intelligence score	0.2	0.4	0.6	-0.4	0.8
Neuroticism score	0.2	0.5	0.8	-0.4	-0.9
Worrier / anxious feelings	0.2	0.3	0.6	-0.8	-0.1
Happiness	0.2	0.3	0.3	0.6	-0.5
Mouth/teeth dental problems: Dentures	0.2	0.3	0.6	0.3	-0.8
Trunk predicted mass	0.2	1.4	2.4	1.6	-0.7
Glaucoma (self-reported)	0.2	0.2	0.3	-0.5	0.4
Medication for pain relief, constipation, heartburn	0.2	0.3	0.4	-0.6	0.6
Migraine (self-reported)	0.2	0.2	0.4	-0.2	0.7
Medication: Omeprazole	0.2	0.2	0.3	0.6	-0.3
Medication: Seretide 50 evohaler	0.2	0.2	0.4	0.6	0.1
Comparative height size at age 10	0.2	1.3	1.6	1.3	-1.0
Hypertension (Self-reported)	0.2	0.6	1.1	1.0	-0.4
Illnesses of siblings: Diabetes	0.2	0.2	0.4	0.3	-0.6
Loneliness, isolation	0.2	0.3	0.6	0.2	-0.8
Ever had bowel cancer screening	0.2	0.2	0.5	0.0	-0.7
Smoking status: Current	0.2	0.3	0.5	-0.7	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	1.0	-1.0	0.1
Number of self-reported non-cancer illnesses	0.2	0.4	0.6	0.8	-0.4
Miserableness	0.2	0.3	0.4	0.4	-0.6
Wears glasses or contact lenses	0.2	0.2	0.4	0.6	-0.1
Mother’s age at death	0.2	0.3	0.3	0.4	0.6
Financial situation satisfaction	0.2	0.3	0.3	-0.5	0.6
Eye problems/disorders: Glaucoma	0.2	0.3	0.5	-0.7	0.2
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.4	0.6	0.1
Unable to work because of sickness or disability	0.2	0.2	0.3	-0.4	0.5
Bipolar Disorder or Schizophrenia	0.1	0.1	0.2	0.5	0.2
Verbal and Numeric Reasoning (VNR)	0.1	0.1	0.3	-0.1	0.5
Breast Cancer	0.1	0.1	0.2	-0.2	0.5
Mean Putamen Volume	0.1	0.1	0.1	0.1	0.3
Rheumatoid Arthritis	0.1	0.1	0.2	0.4	0.3
Blood Platelet Count	0.1	0.6	1.2	0.1	-1.1
Cardiovascular Disease	0.1	0.4	0.6	0.4	0.8
Hypothyroidism (self reported)	0.1	0.1	0.2	-0.2	0.4
Chronotype (morning person)	0.1	0.2	0.2	-0.4	0.4
Tanning	0.1	1.1	1.3	-1.1	0.9
Angina	0.1	0.1	0.1	0.3	0.2
Medication: Co-codamol	0.1	0.1	0.3	0.2	0.5
Townsend deprivation index at recruitment	0.1	0.1	0.2	0.5	-0.3
Fed-up feelings	0.1	0.1	0.2	0.1	-0.5
Serious illness, injury or assault to yourself	0.1	0.1	0.1	0.4	0.1
Stomach or abdominal pain in last month	0.1	0.1	0.1	-0.4	0.2
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.1	-0.3	-0.2
Medication: Atenolol	0.1	0.1	0.1	0.3	0.3
Chronic bronchitis/emphysema (father)	0.1	0.1	0.2	0.2	-0.5
Alcohol usually taken with meals	0.1	0.2	0.3	0.1	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.1	0.2	-0.5	-0.2
Qualifications: None of the above	0.1	0.2	0.4	-0.7	-0.2
Allergy	0.1	0.3	0.3	-0.5	0.6
Father’s age at death	0.1	0.2	0.2	-0.4	0.5
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.2	0.5	0.0
Falls in the last year	0.1	0.1	0.2	0.4	0.1
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	0.4	-0.6	0.5
Depression (self-reported)	0.1	0.1	0.1	-0.2	-0.3
Standing height	0.1	0.6	0.8	-0.7	0.9
Exposure to tobacco smoke at home	0.1	0.1	0.2	-0.1	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.2	0.2	0.5
Birth weight of first child	0.1	0.1	0.2	-0.1	0.4
Mouth/teeth dental problems: Bleeding gums	0.1	0.2	0.3	0.2	-0.6
Medication: Amlodipine	0.1	0.1	0.2	0.2	0.4
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.2	-0.4	0.3
Birth weight	0.1	0.3	0.5	0.7	0.4
High blood pressure (siblings)	0.1	0.1	0.2	0.2	0.5
Number of full brothers	0.1	0.1	0.1	0.3	0.1
Age at first live birth	0.1	0.1	0.2	-0.4	0.2
Shortness of breath walking on level ground	0.1	0.1	0.1	0.4	-0.2
Qualifications: College or University degree	0.1	0.2	0.5	0.7	0.1
Medication: Ibuprofen	0.1	0.2	0.3	0.1	-0.6
Number of full sisters	0.1	0.2	0.2	-0.4	-0.4
Overall health rating	0.1	0.2	0.3	-0.2	-0.6
Chest pain or discomfort	0.1	0.1	0.2	-0.0	-0.4
Age at last live birth	0.1	0.1	0.2	0.2	-0.4
Medication: Aspirin	0.1	0.1	0.2	-0.4	0.2
Average weekly red wine intake	0.1	0.1	0.2	0.5	-0.1
Qualifications: nursing, teaching	0.1	0.1	0.1	0.4	0.4
Medication for cholesterol	0.1	0.2	0.3	-0.6	0.1
Asthma (self-reported)	0.1	0.1	0.1	0.4	-0.3
Medication: Aspirin	0.1	0.2	0.2	-0.4	0.4
Guilty feelings	0.1	0.2	0.4	-0.6	0.1
Medication: Atorvastatin	0.1	0.1	0.2	-0.2	0.5
Myopia	0.1	0.2	0.3	0.5	-0.3
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	-0.1	-0.1
HDL Cholesterol	0.0	0.1	0.1	0.4	-0.0
Lupus	0.0	0.0	0.1	-0.2	-0.2
Heel T-Score	0.0	0.1	0.2	-0.5	-0.1
Height	0.0	0.4	0.5	-0.7	0.6
Respiratory disease	0.0	0.0	0.1	0.2	-0.1
Hair Pigment	0.0	0.8	0.9	-0.9	0.9
Medication for hormone replacement therapy	0.0	0.0	0.0	-0.2	0.0
Severe depression (siblings)	0.0	0.0	0.0	-0.2	-0.2
Current tobacco smoking	0.0	0.1	0.1	-0.3	-0.0
Hayfever, allergic rhinitis or eczema	0.0	0.0	0.0	-0.2	0.1
Sitting height	0.0	0.1	0.2	0.5	-0.2
Number of incorrect matches in round	0.0	0.1	0.1	0.2	-0.3
Asthma	0.0	0.1	0.1	0.3	-0.2
Medication: Ibuprofen (e.g. Nurofen)	0.0	0.0	0.0	-0.0	-0.0
Hair/balding pattern: Pattern 4	0.0	0.0	0.0	-0.1	0.2
Peak expiratory flow (PEF)	0.0	0.1	0.1	0.3	-0.3
Ever highly irritable/argumentative for 2 days	0.0	0.0	0.1	-0.2	-0.2
Qualifications: O levels/GCSEs or equivalent	0.0	0.0	0.0	-0.1	0.2
Gout (self-reported)	0.0	0.0	0.0	-0.1	0.0
Hypothyroidism/myxoedema (self-reported)	0.0	0.0	0.0	0.2	0.1
Health satisfaction	0.0	0.1	0.1	-0.3	0.2
Neck or shoulder pain in last month	0.0	0.0	0.1	-0.2	-0.1
Angina (self-reported)	0.0	0.0	0.0	0.2	0.2
Medication: Allopurinol	0.0	0.0	0.0	-0.1	0.1
Mean time to correctly identify matches	0.0	0.0	0.1	-0.0	0.2
Had major operations	0.0	0.0	0.0	0.1	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.1	0.1	-0.1	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.0	0.0	0.0	0.0	0.0
Ever had stillbirth, spontaneous miscarriage or termination	0.0	0.0	0.0	-0.1	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.0	0.0	0.1	-0.2	-0.2
Back pain experienced in last month	0.0	0.0	0.1	-0.3	0.0
Osteoporosis (self-reported)	0.0	0.0	0.1	-0.2	0.1
Tinnitus: Yes, now most or all of the time	0.0	0.0	0.0	-0.1	0.2
Medication: Blood pressure	0.0	0.0	0.1	0.3	-0.1
Medication: Paracetamol	0.0	0.1	0.1	-0.2	-0.3
Age started oral contraceptive pill	0.0	0.1	0.1	-0.3	-0.2
Medication: Omeprazole (e.g. Zanprol)	0.0	0.0	0.0	0.1	-0.1

Hub : Genes

ZNF440

Models

Trait associations