Hub : Genes

ZNF74

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Visceral Omentum 0.1200 0.0580 6.6e-03 0.088 NA 0.052 NA 0.067 2.6e-05 NA 1.1e-03 NA 2.2e-04
2 GTEx Colon Transverse 0.1790 0.0750 1.2e-03 -0.006 NA 0.032 NA 0.003 7.9e-01 NA 1.1e-02 NA 2.3e-01
3 GTEx Esophagus Mucosa 0.1760 0.0550 5.5e-05 0.092 NA 0.092 NA 0.108 1.0e-06 NA 9.9e-07 NA 1.2e-07
4 GTEx Whole Blood 0.1120 0.0510 5.3e-03 0.001 NA 0.008 NA 0.001 2.2e-01 NA 5.4e-02 NA 2.7e-01
5 METSIM Adipose 0.0796 0.0274 1.2e-04 0.034 0.041 0.058 0.053 0.056 7.3e-06 8.0e-07 4.9e-09 2e-08 7.6e-09
6 TCGA Head and Neck Squamous Cell Carcinoma 0.0310 0.0176 5.1e-03 0.017 0.010 0.007 NA 0.010 4.2e-03 2.3e-02 5.4e-02 NA 2.3e-02
7 TCGA Kidney Renal Clear Cell Carcinoma 0.0611 0.0344 2.2e-04 0.021 0.022 0.022 NA 0.022 1.8e-03 1.5e-03 1.3e-03 NA 1.4e-03
8 TCGA Prostate Adenocarcinoma 0.0887 0.0460 1.7e-05 0.029 0.030 0.029 NA 0.023 4.8e-04 4.0e-04 5.0e-04 NA 1.6e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 1.1 1.8 3.5 0.8 0.8 1.6 -0.7 1.1 1.7 1.4 1.9
Bipolar Disorder or Schizophrenia 0.9 2.3 4.2 0.4 1.8 1.5 -1.0 1.8 2.1 1.6 1.2
Depressed Affect (Nagel 2018) 0.5 1.0 3.6 0.3 -1.9 -0.4 0.4 0.3 -1.1 -1.0 -1.2
Depression (Nagel 2018) 0.5 0.8 1.5 0.6 -0.8 0.6 0.9 1.0 1.2 1.2 0.6
Intelligence (Savage-Jansen 2018) 0.5 1.6 3.1 0.9 -1.7 -1.3 1.6 -0.1 -1.8 -0.1 -1.0
Neuroticism (Nagel 2018) 1.0 2.4 5.9 -0.2 -1.7 -1.6 -0.5 -0.6 -2.1 -1.7 -2.4
Schizophrenia (2018) 0.5 1.0 2.8 -0.2 1.7 0.6 -0.8 1.5 1.3 0.9 0.0
Schizophrenia vs Biploar Disorder 0.3 0.4 1.1 -0.2 -1.1 0.1 -1.0 0.6 -0.2 0.1 -0.6
Worry (Nagel 2018) 0.2 0.5 1.5 0.5 -0.5 -0.2 -0.2 1.2 -0.7 -0.2 -1.1
Alzheimer’s Disease (in mother) 0.5 0.6 2.6 -1.6 0.7 -0.9 0.1 0.1 -0.8 0.2 -0.3
Alzheimer’s Disease (in father) 1.2 1.3 3.7 -0.1 -0.2 1.4 0.5 1.7 1.2 0.4 1.9
Alzheimer’s Disease (including proxy) 0.3 0.4 2.4 -1.6 0.1 -0.4 -0.2 0.2 -0.5 0.0 0.3
Crohns Disease (2017) 0.6 1.3 5.6 -0.9 -0.8 0.9 1.4 2.4 0.3 0.1 0.8
Irritable Bowel Disease (IBD) 0.4 0.9 2.5 0.2 -0.7 0.7 0.8 1.6 0.4 1.0 1.3
Ulcerative Colitis (UC) 0.5 0.9 2.6 1.4 -0.1 0.3 0.2 0.9 0.6 1.6 1.3
Major Depression (MDD) 0.4 0.5 1.1 -0.6 0.8 -0.6 -1.1 -0.9 -0.3 -0.2 -0.6
Reaction Time 1.5 2.9 7.2 -0.9 -1.9 -2.1 -0.3 -0.5 -2.7 -1.9 -1.7
Verbal and Numeric Reasoning (VNR) 0.5 1.1 3.9 0.9 -2.0 -0.6 1.3 -0.0 -0.9 1.1 0.1
Breast Cancer 0.3 0.6 1.5 0.6 -0.3 -0.9 -0.8 -0.6 -0.9 -0.7 -1.2
Ovarian Cancer 0.7 0.9 3.1 0.0 0.5 -1.1 -0.4 -0.8 -1.1 -1.8 -0.7
Prostate Cancer 0.4 0.5 2.2 -0.1 0.4 -0.1 0.7 0.2 0.7 -0.9 -1.5
Age at First Birth 0.2 0.3 1.1 1.1 -0.9 -0.1 0.3 -0.4 -0.2 0.3 0.1
Bipolar Disorder (2011) 0.8 0.8 2.1 0.8 0.0 0.9 0.0 -0.9 1.4 1.2 0.9
Body Mass Index (BMI) (2010) 0.4 0.5 1.5 0.2 -0.0 -0.5 -1.2 -0.3 -1.0 -0.6 -0.9
Coronary Artery Disease (CAD) 0.9 1.1 2.8 0.0 -1.6 -0.4 1.7 -1.6 -0.5 -0.1 0.2
Crohns Disease (2012) 0.5 0.8 3.3 0.1 -0.5 0.3 1.8 1.5 0.2 0.3 0.4
Mean Putamen Volume 0.1 0.1 0.6 0.2 -0.2 0.8 -0.4 0.2 -0.3 -0.4 -0.4
Fasting Glucose 1.7 2.0 4.9 -1.1 0.5 -2.1 -0.9 0.7 -1.5 -2.2 -1.4
HbA1C 1.3 1.4 3.0 0.7 1.7 1.7 0.1 -0.1 1.2 1.0 1.6
HDL Cholesterol 0.3 0.5 1.6 -1.1 -0.3 -0.2 1.0 1.2 -0.2 -0.5 0.3
LDL Cholesterol 0.2 0.3 1.7 0.3 1.3 -0.5 0.5 -0.3 -0.0 0.2 -0.0
Lupus 1.0 1.5 3.9 2.0 0.3 1.4 0.2 1.9 1.4 0.7 0.4
Neuroticism (2016) 1.0 1.5 3.4 -1.8 0.7 -0.9 0.8 0.6 -1.6 -1.5 -1.0
Primary Biliary Cirrhosis 0.7 1.0 1.8 0.3 1.2 1.3 -0.6 1.1 0.8 0.8 1.3
Rheumatoid Arthritis 0.6 0.8 2.7 -0.7 0.3 0.7 1.7 1.6 0.4 -0.1 0.5
Schizophrenia (2014) 0.4 1.0 2.0 0.8 1.4 0.7 -0.9 1.0 1.3 1.1 0.4
Triglycerides 0.1 0.2 0.4 0.1 0.6 -0.1 -0.7 -0.5 -0.2 0.3 -0.5
Type 2 Diabetes (T2D) (2012) 0.8 0.9 4.0 -1.1 0.4 -0.5 -2.0 -1.0 -0.3 -0.0 -0.6
Ulcerative Colitis 0.3 0.4 1.1 1.0 0.6 -0.3 -0.0 1.1 -0.2 0.7 0.5
Blood Eosinophil Count 0.4 2.8 13.8 3.7 -2.5 0.5 -0.3 0.2 0.1 1.1 0.9
Blood Platelet Count 0.3 3.0 5.7 1.5 -1.9 1.8 1.8 0.0 1.8 2.4 1.5
Blood Red Count 0.1 0.7 2.9 -0.9 0.1 0.2 -1.7 -0.7 0.4 1.0 -0.1
Blood White Count 0.5 3.9 11.7 2.4 -3.4 0.7 -1.1 -2.8 0.9 1.4 1.3
Heel T-Score 0.1 0.5 1.8 -0.1 1.0 -0.1 -0.0 1.3 -0.4 0.0 0.9
BMI 0.7 4.1 15.9 -1.7 -0.6 -0.9 -3.4 -4.0 -0.7 -0.5 -0.7
Height 0.5 9.3 46.5 -1.4 0.0 -1.5 6.8 3.2 -1.0 -1.1 -3.3
Waist Hip Ratio (WHR) 1.0 4.3 9.9 -1.1 2.6 2.2 -0.9 0.3 3.2 2.1 2.6
Systolic Blood Pressure 0.3 1.6 5.0 0.4 -2.2 0.2 2.2 1.4 0.5 -0.3 0.9
Smoking Status 0.3 0.7 1.2 -1.0 -0.4 -1.0 1.0 -0.2 -0.8 -0.6 -1.1
Allergy or Eczema 0.7 1.8 3.1 1.8 0.7 1.6 0.5 1.7 1.4 1.3 1.2
Cardiovascular Disease 0.4 1.4 2.5 1.0 -1.4 1.6 1.5 0.7 1.0 0.9 1.1
Hypothyroidism (self reported) 0.3 0.8 4.8 -0.0 0.3 0.3 2.2 0.6 0.7 0.5 0.5
Respiratory disease 2.3 5.1 10.6 -1.2 1.3 2.9 0.7 2.7 2.9 3.3 1.7
Type 2 Diabetes (T2D) (2018) 1.6 3.0 5.2 -1.4 0.7 2.1 -1.2 1.3 2.3 1.9 2.1
Lung FEV1/FVC ratio 4.3 21.8 44.0 -2.6 -3.1 -5.5 -3.7 -6.2 -6.6 -4.7 -3.2
Lung FVC 0.1 0.7 2.0 -0.6 0.0 -1.2 -0.3 -1.4 -0.8 -0.1 -0.9
Neuroticism 0.6 1.4 3.9 -1.0 -0.2 -1.2 0.2 0.1 -1.5 -2.0 -1.6
Chronotype (morning person) 0.4 0.9 3.8 0.1 1.6 0.1 -2.0 0.4 0.5 0.6 0.5
Hair Pigment 0.0 1.2 3.3 1.6 -1.8 1.1 0.4 1.0 -0.3 0.9 0.4
Tanning 0.0 0.6 2.9 -0.9 1.7 0.2 -0.6 -0.0 0.3 0.6 -0.4
Hand grip strength (left) 0.1 0.4 1.4 -0.3 1.2 0.4 -1.1 -0.1 -0.1 0.0 0.1
Number of treatments/medications taken 0.6 1.0 2.0 0.8 0.0 1.4 0.2 1.4 1.0 1.4 0.7
Average weekly spirits intake 0.6 0.7 2.0 0.5 -0.1 -1.2 -0.1 -0.9 -0.7 -0.8 -1.4
Sensitivity / hurt feelings 1.9 3.2 7.7 -1.1 -1.9 -1.8 -0.1 -1.0 -2.2 -2.8 -2.0
Frequency of depressed mood in last 2 weeks 0.9 1.2 2.1 1.3 -0.2 1.2 0.7 1.3 1.4 1.0 1.1
Hearing difficulty/problems: Yes 0.1 0.1 0.9 -0.2 -0.1 -0.2 0.9 0.3 -0.2 -0.2 0.0
Relative age of first facial hair 0.2 0.4 1.4 0.0 0.1 0.3 -1.0 -1.2 0.5 0.5 -0.2
Other serious medical condition/disability diagnosed by doctor 0.6 0.7 1.7 0.6 -1.3 -1.1 0.1 0.2 -0.7 -1.3 -0.5
Ever used hormone-replacement therapy (HRT) 0.5 0.6 3.4 0.9 -1.8 -0.0 -0.3 -0.5 -0.3 0.1 0.2
Ever had hysterectomy (womb removed) 1.7 1.9 3.3 0.0 1.4 1.7 -0.5 1.6 1.4 1.8 1.5
Systolic blood pressure, automated reading 0.3 0.8 4.8 -0.5 0.1 0.3 -0.2 2.2 0.3 -0.4 0.9
Eye problems/disorders: Diabetes related eye disease 0.4 0.5 1.2 -0.6 -0.6 1.0 -1.1 0.7 0.1 0.6 0.2
Angina 1.9 2.6 6.6 0.5 -1.3 -2.3 0.2 -1.2 -1.8 -1.3 -2.6
Medication for hormone replacement therapy 1.0 1.1 3.7 0.8 -0.8 0.7 1.9 -0.0 0.6 0.3 1.8
Vitamin and mineral supplements 0.5 0.7 3.1 -0.3 -1.2 -0.8 0.0 -1.8 -0.1 0.7 0.4
Supplements: Zinc 0.3 0.4 2.0 -0.2 0.6 -0.1 0.0 1.4 -0.2 0.3 -0.6
Medication: Co-codamol 0.2 0.2 0.7 -0.5 0.1 -0.5 0.2 -0.8 -0.5 -0.1 -0.7
Medication: Metformin 0.4 0.6 1.7 -1.3 0.9 0.2 -0.9 -0.2 0.1 0.5 1.0
Diabetes (father) 0.3 0.4 1.4 0.2 -0.7 -0.8 -0.3 -1.2 0.4 -0.2 -0.5
Diabetes (mother) 3.9 5.0 14.1 -1.3 1.7 2.5 -2.3 -0.1 2.7 3.8 1.8
Severe depression (siblings) 0.1 0.2 0.6 0.8 -0.4 -0.2 0.5 0.1 -0.3 -0.4 -0.2
Pack years adult smoking proportion 0.7 1.1 2.4 0.4 -1.0 1.5 1.2 1.5 1.1 0.5 0.7
Impedance of leg (right) 1.5 7.2 20.0 2.8 0.7 2.7 3.1 4.5 2.8 2.1 0.5
Leg fat-free mass (left) 0.3 1.6 7.2 -2.7 -0.7 -0.8 0.1 -1.6 -1.0 -0.8 -0.1
Trunk fat percentage 0.1 0.3 1.5 -0.2 -0.7 0.1 -0.5 -0.1 0.6 1.2 0.1
Hand grip strength (right) 0.1 0.4 1.1 0.2 -0.2 -0.5 -1.0 -0.3 -1.1 -0.5 -0.6
Townsend deprivation index at recruitment 0.3 0.4 0.6 -0.7 -0.4 0.8 -0.6 -0.5 0.6 0.3 0.7
Current tobacco smoking 0.2 0.3 0.9 -0.5 -0.5 0.1 0.4 1.0 -0.5 0.7 -0.7
Average weekly fortified wine intake 0.6 0.7 2.8 0.8 -0.7 -0.7 -1.7 0.1 -0.5 -0.8 0.2
Maternal smoking around birth 0.2 0.3 1.1 -0.4 0.1 0.1 0.7 1.0 0.4 0.7 -0.3
Fed-up feelings 0.6 1.0 3.9 1.5 -2.0 0.3 -0.1 -0.2 -0.6 -1.1 -0.5
Frequency of unenthusiasm / disinterest in last 2 weeks 0.4 0.5 1.3 1.1 -1.1 -0.0 -0.6 -0.4 0.7 0.3 0.5
Relative age voice broke 0.3 0.4 1.3 -0.8 0.8 -0.0 -0.6 -1.1 0.4 0.6 0.3
Taking other prescription medications 0.6 1.0 1.9 1.1 -1.1 1.2 -0.1 0.9 1.4 0.4 1.0
Age when periods started (menarche) 0.1 0.2 0.7 -0.4 -0.0 -0.3 -0.2 -0.8 -0.3 -0.3 0.5
Bilateral oophorectomy (both ovaries removed) 1.7 1.9 5.2 0.8 0.5 1.7 -0.3 -0.3 1.5 2.0 2.3
Heel bone mineral density (BMD) T-score, automated (left) 1.9 4.3 7.0 2.0 2.0 2.3 1.1 2.6 2.1 2.2 1.8
Tinnitus: Yes, but not now, but have in the past 0.8 0.9 2.4 -0.3 0.8 1.2 -1.1 -0.3 1.1 1.5 0.2
Qualifications: CSEs or equivalent 0.5 0.7 2.1 -0.7 -0.1 1.4 0.3 0.2 1.3 0.6 1.0
Serious illness, injury or assault to yourself 0.4 0.5 1.4 0.1 -0.2 0.6 1.0 0.1 0.9 1.2 0.5
High blood pressure 0.8 2.2 4.9 0.5 -1.0 1.8 2.0 2.2 1.0 1.5 1.0
Hayfever, allergic rhinitis or eczema 0.9 1.9 8.0 2.8 0.2 1.5 -0.2 0.9 1.4 1.0 1.1
Multivitamins +/- minerals 0.3 0.4 1.5 -0.1 1.2 0.9 0.2 0.1 0.6 -0.2 -0.6
Stomach or abdominal pain in last month 0.4 0.5 1.9 0.6 -1.4 -0.2 0.7 -1.1 -0.0 -0.5 -0.1
Supplements: Glucosamine 1.1 1.5 4.3 -0.5 2.1 1.4 0.4 1.2 0.9 1.5 0.8
Diverticular disease/diverticulitis (self-reported) 1.0 1.2 4.4 -1.9 1.0 -0.2 -2.1 -0.7 -0.2 -0.4 -0.2
Medication: Atenolol 1.6 2.0 6.9 0.4 -2.6 -1.6 -0.4 -1.1 -1.7 -0.8 -1.2
Medication: Levothyroxine sodium 0.5 0.9 5.0 -0.6 -0.3 0.2 2.2 0.9 0.2 0.1 1.0
Sitting height 0.3 1.8 5.3 -0.3 0.5 1.4 2.3 1.5 0.7 1.5 1.4
Chronic bronchitis/emphysema (father) 0.9 1.1 2.9 -1.7 0.0 -1.4 -0.2 -1.1 -0.5 -0.9 -1.2
High blood pressure (mother) 1.7 2.4 6.6 -2.6 -0.9 -1.4 -0.1 -1.2 -1.3 -1.4 -2.2
Body mass index (BMI) 0.6 2.5 9.9 -1.5 -0.7 -0.6 -3.2 -2.5 -0.2 -0.0 0.4
Impedance of leg (left) 1.7 8.2 21.8 3.4 0.5 2.7 3.2 4.7 2.7 2.5 0.8
Leg predicted mass (left) 0.3 1.5 7.1 -2.7 -0.8 -0.8 0.1 -1.5 -0.9 -0.7 -0.0
Trunk fat mass 0.1 0.3 1.3 -1.1 -0.5 -0.1 -0.4 -0.3 0.3 0.8 0.2
Waist circumference 0.4 1.4 6.3 -2.5 0.2 0.2 -1.7 -0.8 0.6 0.8 0.9
Number of incorrect matches in round 0.6 1.0 3.9 0.1 -0.6 1.4 -2.0 1.4 0.2 0.2 -0.0
Past tobacco smoking 0.4 0.7 1.8 0.3 0.8 1.0 -1.3 0.2 0.8 1.2 0.4
Alcohol usually taken with meals 0.6 1.0 2.5 -1.5 -0.5 -0.2 0.3 0.8 -1.1 -1.6 -1.0
Nervous feelings 0.3 0.5 1.6 1.3 -1.1 0.4 -0.9 0.1 0.1 0.4 -0.4
Frequency of tenseness / restlessness in last 2 weeks 0.7 1.0 2.1 1.0 -1.5 0.5 1.1 1.1 0.8 0.9 1.2
Hearing difficulty/problems with background noise 0.8 1.2 3.1 -0.2 -0.6 -0.9 -0.0 -0.2 -1.7 -1.6 -1.7
Hair/balding pattern: Pattern 2 1.2 1.5 5.8 -2.4 -0.1 0.9 0.4 -1.2 1.2 0.8 1.3
Had menopause 1.6 2.0 4.0 -1.3 -1.7 -1.4 0.0 -0.1 -1.9 -1.3 -2.0
Had other major operations 1.6 1.9 4.6 0.9 -1.8 -2.2 -1.4 -0.1 -1.5 -1.4 -0.6
Forced vital capacity (FVC) 0.2 0.7 4.3 0.5 1.0 -0.2 2.1 -0.4 -0.0 -0.1 0.1
Heel bone mineral density (BMD) T-score, automated (right) 1.0 2.3 4.9 2.2 1.7 1.0 0.4 2.1 1.0 1.4 1.3
Ever unenthusiastic/disinterested for a whole week 1.2 1.5 2.9 -1.5 -1.5 -1.4 0.6 -0.2 -1.7 -1.6 -0.3
Qualifications: None of the above 1.2 2.5 4.3 -1.8 1.9 1.5 -1.6 0.4 1.7 2.1 1.1
Financial difficulties in last 2 years 0.3 0.4 1.0 0.6 -1.0 0.4 -0.9 -0.7 0.6 0.1 0.4
Mouth/teeth dental problems 0.6 1.0 3.9 2.0 -0.3 0.2 1.8 0.2 0.1 -0.7 0.1
Heart attack 1.1 1.4 4.3 -0.5 -2.1 -1.1 0.0 -0.4 -1.6 -1.5 -1.0
Allergy 1.0 2.3 4.0 -1.3 0.3 -2.0 -0.2 -1.7 -1.9 -2.0 -1.4
Pain all over the body in last month 0.7 0.8 2.2 -0.9 -1.5 -1.3 0.5 -0.0 -0.9 -0.4 -0.7
Diabetes (self-reported) 2.0 3.0 5.3 -1.4 2.0 1.9 -1.8 1.2 1.8 1.4 2.3
Hayfever/allergic rhinitis (self-reported) 0.6 0.8 1.2 1.1 -1.0 0.9 -0.3 -0.7 1.1 1.0 0.4
Medication: Ramipril 0.7 0.9 3.0 -0.2 -1.7 -0.7 0.3 -1.3 -0.4 -1.2 -0.2
Medication: Simvastatin 0.3 0.4 1.5 0.2 -1.0 0.4 0.3 1.2 0.2 0.4 0.4
Fluid intelligence score 0.8 1.7 6.6 0.6 -1.8 -1.1 2.6 0.3 -1.2 0.1 -0.1
Illnesses of siblings 0.7 1.0 2.5 0.0 0.6 -1.4 0.1 -1.1 -1.0 -1.1 -1.6
Neuroticism score 0.9 1.8 3.0 1.4 -1.7 -1.2 -0.1 -0.7 -1.6 -1.7 -1.5
Weight 0.1 0.7 3.2 -1.8 -0.8 -0.4 -0.6 -1.0 -0.2 -0.1 0.1
Impedance of arm (right) 1.0 4.7 9.2 3.0 0.7 1.8 2.6 2.5 2.5 2.2 0.7
Arm fat percentage (right) 0.4 1.5 5.8 -0.3 -0.6 -0.3 -2.4 -2.1 0.5 0.7 0.7
Trunk fat-free mass 0.4 2.1 7.8 -2.8 -0.3 -1.2 0.9 -0.8 -1.5 -1.7 -0.8
Hip circumference 0.3 1.3 3.1 -1.8 -1.5 -1.2 -0.7 -0.8 -1.2 -0.9 -0.7
Time employed in main current job 0.5 0.6 2.5 -0.1 -0.1 -0.6 -0.5 -1.6 -0.5 0.1 -1.0
Alcohol intake versus 10 years previously 0.1 0.2 0.6 -0.2 -0.3 0.4 -0.4 0.4 0.2 0.6 0.8
Father’s age at death 0.4 0.5 2.5 -0.5 0.2 0.2 -0.3 1.6 0.1 -0.4 1.1
Worrier / anxious feelings 0.2 0.4 1.0 0.4 -1.0 0.5 0.5 0.9 0.0 0.3 -0.8
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.6 1.7 0.8 -1.3 0.3 -1.2 -0.7 0.3 0.5 0.3
Falls in the last year 1.3 1.7 2.8 0.2 -1.0 1.6 -0.4 1.6 1.3 1.7 1.6
Hair/balding pattern: Pattern 3 1.6 2.4 6.6 0.0 -1.3 -2.2 -0.8 1.1 -2.6 -1.2 -1.6
Number of live births 0.5 0.7 1.3 0.6 -0.9 -1.0 -0.8 -1.1 -1.2 -0.1 -0.5
Forced expiratory volume in 1-second (FEV1) 0.6 1.9 7.4 0.5 0.5 -1.7 0.9 -2.7 -1.5 -1.2 -0.5
Pulse rate 1.5 2.5 7.3 0.4 0.2 2.3 0.1 0.6 2.0 1.8 2.7
Happiness 0.4 0.5 1.3 1.1 -0.3 0.7 1.2 0.9 -0.2 -0.1 -0.1
Noisy workplace 0.6 0.8 2.1 -0.2 -1.1 0.3 -1.2 -1.4 -0.3 -0.8 -0.6
Qualifications: A levels/AS levels or equivalent 0.2 0.4 2.0 -0.0 0.5 0.6 -0.2 -1.4 0.4 0.5 0.4
Serious illness, injury or assault of a close relative in last 2 years 1.3 1.4 3.6 0.1 -1.4 -1.3 -0.9 -1.9 -1.4 -0.6 -0.9
Mouth/teeth dental problems: Dentures 1.1 1.8 6.2 -1.7 -0.9 -1.2 -2.5 -0.8 -1.0 -0.2 -1.2
Asthma 1.3 2.7 5.2 -1.4 0.0 2.1 0.7 2.1 2.1 2.3 0.2
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 2.6 -0.1 -0.4 0.4 -0.9 -1.6 -0.0 0.7 0.0
Medication: Cholesterol lowering 0.3 0.5 2.9 0.3 -0.2 -0.1 0.6 1.7 -0.1 0.3 0.8
Depression (self-reported) 0.5 0.6 1.3 0.5 -1.1 0.1 0.6 1.1 -0.5 -1.2 0.5
Medication: Lansoprazole 4.5 5.1 18.7 1.1 0.3 2.1 2.3 4.3 1.6 2.1 2.2
Prospective memory result 0.4 0.5 1.9 -0.1 -1.4 -0.5 -0.4 -0.6 -0.8 -0.8 -0.6
Lung cancer (father) 1.3 1.5 2.9 -0.2 1.7 -0.9 -1.5 -1.6 -0.5 -1.4 -1.1
Illnesses of mother 2.3 2.9 9.2 1.9 1.3 1.8 0.1 0.1 2.0 1.0 3.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.6 2.0 5.8 0.2 0.5 -1.5 1.4 -2.4 -1.9 -1.4 -0.7
Pulse wave Arterial Stiffness index 0.4 0.5 1.9 0.1 -1.4 0.2 -1.3 -0.1 -0.6 0.3 -0.1
Impedance of arm (left) 1.5 6.7 11.1 3.1 0.6 2.3 3.2 3.3 2.7 2.9 1.1
Arm fat mass (right) 0.2 0.9 2.7 -1.2 -0.7 -0.4 -1.6 -1.5 0.1 0.4 0.3
Trunk predicted mass 0.4 2.1 7.4 -2.7 -0.3 -1.3 1.0 -0.8 -1.5 -1.7 -0.8
Standing height 0.6 5.9 33.1 -1.0 -0.2 0.3 5.8 3.5 -0.2 -0.2 -0.8
Length of working week for main job 1.1 1.2 3.0 -0.4 0.7 1.7 1.2 -0.4 1.3 1.4 0.6
Exposure to tobacco smoke at home 0.6 0.7 2.8 -1.7 1.1 0.8 0.4 0.1 0.7 0.3 0.5
Breastfed as a baby 0.6 0.7 2.1 -0.1 1.4 -0.4 0.2 -0.5 -0.4 1.0 1.4
Tense / ‘highly strung’ 0.1 0.2 0.5 0.2 -0.6 0.5 -0.2 0.7 0.1 0.3 -0.7
Seen doctor (GP) for nerves, anxiety, tension or depression 0.4 0.6 2.5 1.2 -1.6 0.4 -0.3 -0.2 -0.1 -0.7 -0.2
Hair/balding pattern: Pattern 4 1.3 3.2 8.6 1.2 -2.9 -1.6 -0.2 -0.6 -2.2 -2.3 -1.5
Birth weight of first child 0.5 0.9 3.1 -1.8 1.4 0.4 -0.4 -0.9 0.7 0.8 0.0
Peak expiratory flow (PEF) 0.3 0.8 2.6 0.6 0.1 -1.3 0.1 -1.6 -1.0 -0.5 0.5
Pulse wave reflection index 1.3 1.6 4.2 1.5 -1.8 0.1 -2.0 -0.8 -0.7 -0.4 -1.3
Ever highly irritable/argumentative for 2 days 0.8 0.9 2.0 -1.4 -0.3 -0.9 -0.7 -1.1 -0.7 -1.2 -1.0
Loud music exposure frequency 0.5 0.6 1.8 1.1 0.2 -0.1 -0.8 1.4 -0.1 -0.9 0.4
Qualifications: O levels/GCSEs or equivalent 0.4 0.7 2.0 1.4 -0.6 -1.0 0.1 -0.4 -1.0 -1.0 0.2
Mouth/teeth dental problems: Bleeding gums 0.7 0.8 2.0 -1.4 0.7 0.6 0.6 0.6 0.9 1.1 1.1
Blood clot in the leg (DVT) 0.4 0.6 3.5 1.9 0.4 -0.6 0.2 -0.3 -0.1 -0.6 0.2
Medication: Paracetamol 0.2 0.4 2.0 0.5 -0.8 -0.0 -1.4 -0.3 -0.2 -0.1 -0.3
Headache pain in last month 0.5 0.9 5.1 1.0 -2.2 0.1 -0.4 0.1 -0.1 -0.6 -0.5
Medication for cholesterol, blood pressure or diabetes 1.1 1.8 6.2 0.2 0.1 -1.5 -1.2 -2.5 -1.3 -0.9 -1.4
Glaucoma (self-reported) 0.1 0.1 0.4 0.1 -0.1 0.2 -0.1 -0.4 0.4 0.6 -0.5
Gout (self-reported) 0.4 0.5 1.5 -0.7 -1.0 0.9 0.3 0.2 1.2 0.1 0.2
Hypothyroidism/myxoedema (self-reported) 0.6 1.2 4.4 0.3 -0.3 1.0 2.1 0.9 0.8 0.6 1.6
Medication: Amlodipine 2.1 2.9 5.1 1.1 1.1 2.2 2.1 1.9 1.8 1.9 1.2
Medication: Ventolin 100micrograms inhaler 2.4 3.1 5.5 1.9 1.0 2.3 0.5 1.7 2.2 2.3 1.0
Birth weight 1.1 2.4 6.2 0.1 -1.6 -1.9 -1.1 -2.5 -2.0 -0.9 -0.5
Chronic bronchitis/emphysema (mother) 3.3 3.8 9.9 -0.1 1.3 2.8 1.2 1.8 3.1 2.1 1.6
High blood pressure (siblings) 0.9 1.3 2.6 -1.6 -1.3 -0.9 -0.9 -1.0 -1.1 -1.2 -0.8
Forced vital capacity (FVC), Best measure 0.3 1.0 5.0 -0.2 1.5 0.1 2.2 -0.6 -0.1 -0.1 0.0
Body fat percentage 0.2 0.6 1.7 -0.1 -0.7 0.2 -1.2 -0.7 0.9 1.3 0.5
Leg fat percentage (right) 0.3 1.2 3.8 -0.4 -0.4 0.7 -1.9 -0.6 1.4 1.3 0.9
Arm fat-free mass (right) 0.4 1.9 7.5 -2.7 -0.8 -1.0 0.6 -0.4 -1.6 -1.6 -0.8
Exposure to tobacco smoke outside home 0.3 0.4 1.2 0.7 -1.1 0.3 0.5 -0.8 0.1 -0.4 -0.0
Comparative body size at age 10 0.3 0.7 1.4 -0.4 -1.0 -0.5 -1.2 -1.1 -1.2 -0.7 0.2
Number of full brothers 0.5 0.7 2.7 0.0 -1.6 -0.5 -0.6 -1.1 -0.3 -0.6 -0.5
Worry too long after embarrassment 2.2 3.7 7.8 -0.3 -0.6 -2.8 0.3 -1.0 -2.7 -2.5 -2.6
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.3 1.1 0.4 -0.1 0.5 0.9 1.0 -0.1 -0.4 0.3
Wheeze or whistling in the chest in last year 0.7 1.2 3.2 -1.6 -1.5 0.4 0.6 1.8 -0.5 -0.8 -0.7
Number of children fathered 3.1 3.5 11.0 -0.2 -0.0 -2.6 -0.3 -2.1 -2.0 -1.3 -3.3
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.2 0.7 0.6 0.0 0.2 -0.6 -0.4 -0.3 -0.2 -0.9
Age at first live birth 0.4 0.8 1.7 -1.3 0.2 -1.1 0.6 -0.2 -1.3 -1.0 -0.3
Pulse wave peak to peak time 0.5 0.6 3.0 -0.2 1.3 -0.1 1.7 0.3 0.6 -0.2 0.1
Health satisfaction 0.9 1.1 3.4 -1.9 0.2 -0.6 -0.9 -0.2 -1.3 -1.1 -1.2
Shortness of breath walking on level ground 0.2 0.2 0.9 -1.0 -0.5 -0.4 -0.1 -0.5 -0.2 -0.4 -0.4
Qualifications: College or University degree 0.3 0.9 3.0 0.6 -1.0 -0.3 -0.2 -1.7 -0.9 -0.5 -1.3
Eye problems/disorders: None of the above 1.6 1.9 6.5 0.6 1.1 1.4 0.0 -0.7 1.6 1.4 2.6
Mouth/teeth dental problems: Loose teeth 0.2 0.2 0.9 0.2 1.0 -0.1 0.7 0.1 -0.3 -0.0 0.1
Emphysema/chronic bronchitis 0.8 0.9 3.2 -1.0 -0.2 0.5 0.9 1.8 0.6 1.2 0.4
Medication for pain relief, constipation, heartburn 0.7 1.1 2.4 0.3 1.5 1.0 0.9 0.5 1.3 0.8 1.4
Neck or shoulder pain in last month 0.9 1.3 6.9 -2.6 0.7 0.0 -1.0 -0.0 -0.4 0.2 -1.5
Medication: Blood pressure 0.8 1.4 3.5 -0.1 -0.5 1.5 0.6 1.9 1.4 1.4 1.0
Angina (self-reported) 2.1 2.7 6.7 0.2 -1.2 -2.5 0.4 -1.2 -1.9 -1.5 -2.6
Migraine (self-reported) 1.5 1.8 5.3 -1.2 -0.2 -1.5 -1.1 -0.7 -1.6 -2.3 -1.1
Medication: Ibuprofen 0.4 0.5 2.3 0.0 0.1 0.6 -0.6 -1.5 0.2 0.9 -0.3
Medication: Allopurinol 0.5 0.7 2.2 -0.0 0.1 1.0 -0.2 0.3 1.5 1.0 1.0
Medication: Omeprazole 0.3 0.3 0.9 -0.8 -0.4 0.3 0.5 -0.5 0.0 1.0 0.6
Medication: Seretide 50 evohaler 0.6 0.6 2.8 1.1 -0.9 0.2 0.1 1.7 0.5 -0.1 -0.1
Mean time to correctly identify matches 1.0 2.0 4.7 -1.4 -0.7 -1.7 -0.1 0.6 -2.2 -1.5 -1.8
Heart disease (mother) 7.9 9.6 20.0 -1.6 -2.5 -3.6 -0.5 -1.4 -4.2 -3.9 -4.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.5 0.5 1.5 0.5 -0.3 -1.2 0.6 -0.0 -0.9 -0.9 -0.7
Whole body fat mass 0.1 0.5 1.5 -1.2 -0.7 0.0 -0.9 -0.7 0.4 0.8 0.2
Leg fat mass (right) 0.3 1.0 2.3 -1.3 -0.7 0.6 -1.5 -0.8 0.8 0.9 0.9
Arm predicted mass (right) 0.4 1.9 6.8 -2.6 -0.7 -1.2 0.7 -0.6 -1.6 -1.5 -1.0
Pulse rate, automated reading 0.6 1.8 4.5 0.5 -0.3 2.1 -1.2 -0.6 1.3 1.6 1.9
Alcohol intake frequency. 0.4 1.0 2.5 1.1 -1.6 0.6 -1.5 -0.2 0.0 0.9 0.7
Comparative height size at age 10 0.9 4.9 25.5 -1.6 0.2 0.8 5.0 2.7 1.1 1.4 -0.2
Number of full sisters 1.4 1.8 6.6 -0.1 0.1 1.2 -0.6 -0.9 1.6 2.6 1.5
Suffer from ‘nerves’ 0.2 0.3 1.1 0.3 0.9 0.1 -0.7 1.1 -0.5 -0.4 -0.0
Overall health rating 0.3 0.7 1.9 0.8 -1.4 0.8 -1.0 1.2 0.3 0.2 0.5
Chest pain or discomfort 1.1 1.5 4.7 1.8 -2.2 -0.5 0.3 -1.4 -0.8 -1.3 -0.1
Had major operations 1.7 1.9 8.0 0.2 -2.8 -0.9 -0.5 0.1 -0.5 -0.6 -2.4
Age at last live birth 0.3 0.5 1.2 -1.0 0.1 0.3 -0.4 -0.9 0.6 1.1 0.3
Family relationship satisfaction 0.2 0.3 1.6 -0.7 0.1 0.4 -1.3 0.0 0.2 0.2 0.2
Leg pain on walking 0.6 0.7 1.8 -0.5 -0.6 -0.9 -0.6 -0.5 -1.3 -1.2 -0.6
Qualifications: NVQ or HND or HNC or equivalent 1.0 1.3 3.1 -0.7 -0.1 0.7 1.8 0.4 1.6 1.3 1.3
Commuting to job workplace: Car/motor vehicle 0.7 0.8 1.7 -0.9 -0.1 -1.3 0.4 -1.0 -1.3 0.2 -1.0
Illness, injury, bereavement, stress in last 2 years 0.4 0.5 1.1 1.0 0.7 -0.6 -0.4 1.0 -0.3 -0.9 0.3
Medication: Aspirin 0.7 1.0 2.1 -0.9 -1.5 -0.7 -0.1 0.4 -1.1 -1.0 -1.4
Supplements: Vitamin C 0.2 0.3 1.6 0.4 0.2 -0.2 0.5 1.3 -0.3 -0.2 -0.1
Knee pain experienced in last month 1.4 2.1 6.5 -0.2 0.0 2.6 0.1 1.3 1.9 1.2 2.0
Hypertension (Self-reported) 0.9 2.4 4.1 0.3 -1.2 2.0 2.0 2.0 1.2 1.7 0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.9 1.0 4.2 -0.0 0.8 1.2 0.0 0.9 0.9 2.0 0.5
Illnesses of father: Heart disease 0.8 1.1 2.8 -0.7 -1.7 -0.8 1.6 -0.3 -0.9 -1.3 -0.1
Illnesses of siblings: Diabetes 2.0 2.5 5.8 0.3 0.8 2.4 -0.7 1.1 2.3 1.9 1.7
Smoking status: Previous 0.9 1.3 2.9 -0.6 -1.3 -1.2 1.0 -0.4 -1.3 -1.7 -0.9
Forced expiratory volume in 1-second (FEV1), predicted 0.9 2.0 4.1 -0.1 1.7 1.7 2.0 -0.1 1.9 1.1 0.9
Whole body fat-free mass 0.3 2.0 8.1 -2.8 -0.5 -1.1 0.6 -1.1 -1.4 -1.4 -0.6
Leg fat-free mass (right) 0.3 1.3 5.9 -2.4 -0.7 -0.8 0.3 -1.5 -1.0 -0.6 0.1
Arm fat percentage (left) 0.3 1.2 5.0 -0.6 -0.5 -0.1 -2.2 -1.5 0.6 1.0 0.7
Average weekly red wine intake 0.4 0.5 2.3 -0.2 0.7 0.8 -1.5 0.8 0.4 0.3 0.0
Handedness (chirality/laterality): Left-handed 0.4 0.4 1.0 1.0 -0.8 0.3 0.8 -0.5 0.4 0.6 0.6
Mood swings 0.8 1.4 3.0 1.5 -0.6 1.7 1.1 0.5 1.6 1.2 0.6
Loneliness, isolation 0.5 0.6 1.8 1.3 -0.6 -0.4 1.1 0.9 -0.8 0.2 -0.3
Long-standing illness, disability or infirmity 1.3 2.0 7.9 -0.2 -2.8 -1.3 0.6 0.0 -1.6 -1.6 -0.9
Ever had bowel cancer screening 1.3 1.5 4.1 -0.4 2.0 0.8 0.4 0.9 1.1 1.3 1.7
Diabetes diagnosed by doctor 2.4 4.0 5.7 -1.3 2.0 2.3 -1.9 1.9 2.0 2.0 2.4
Ever had stillbirth, spontaneous miscarriage or termination 0.4 0.4 1.2 0.7 -1.1 -0.4 0.6 -0.6 0.0 0.0 0.9
Friendships satisfaction 0.2 0.2 0.5 0.6 -0.6 0.1 0.0 0.2 -0.3 -0.6 -0.7
Qualifications: nursing, teaching 0.2 0.4 1.2 -1.1 0.9 0.6 0.3 -0.4 -0.1 0.3 -0.4
Commuting to job workplace: Walk 0.8 0.9 3.9 -0.8 -0.4 0.7 2.0 -0.0 0.9 0.8 0.5
Eye problems/disorders: Cataract 0.6 0.7 3.1 -0.3 0.0 -1.0 0.4 -0.6 -1.0 0.1 -1.8
Mouth/teeth dental problems: Mouth ulcers 0.5 0.8 2.3 -0.4 0.3 1.5 -0.9 -0.9 1.1 0.9 0.7
Medication for cholesterol 0.4 0.6 2.0 0.3 -0.4 -0.4 -0.9 0.3 -0.7 -0.8 -1.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.5 0.6 3.0 -0.8 -0.2 -0.7 1.7 -0.1 -0.4 -0.6 0.0
Back pain experienced in last month 0.6 0.9 2.1 -1.4 0.7 0.8 -1.4 -0.5 0.3 1.0 0.9
Mineral and other dietary supplements 1.1 1.4 5.5 0.6 -1.5 -1.3 1.2 -2.3 -0.4 -0.3 0.4
Breast cancer (self-reported) 0.8 1.0 4.8 -2.2 0.2 0.7 0.4 1.4 -0.0 0.2 -0.5
Asthma (self-reported) 1.5 2.9 5.7 -1.3 0.2 2.1 0.5 2.3 2.3 2.4 0.5
Osteoporosis (self-reported) 0.3 0.4 1.8 -0.3 -0.1 -0.9 0.4 0.4 -1.4 -0.1 -0.5
Osteoarthritis (self-reported) 1.1 1.5 3.1 -1.5 0.2 1.8 0.4 0.3 1.5 1.7 1.0
Medication: Aspirin 0.8 1.0 3.0 -0.8 -1.7 -0.5 0.0 0.7 -0.9 -1.0 -1.3
Medication: Gliclazide 0.3 0.3 0.8 -0.2 -0.3 0.9 0.5 0.6 0.6 0.7 0.2
Illnesses of father: None of the above (group 1) 0.5 0.6 2.7 0.6 1.6 0.4 0.1 0.0 0.1 1.3 0.4
Smoking status: Current 0.2 0.3 0.7 -0.4 -0.1 0.1 0.3 0.7 -0.2 0.8 -0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 2.4 5.1 18.0 1.1 0.4 -3.0 -0.4 -4.2 -2.8 -1.7 -1.4
Whole body water mass 0.4 2.1 7.8 -2.8 -0.6 -1.2 0.6 -1.2 -1.5 -1.6 -0.7
Leg predicted mass (right) 0.3 1.4 6.0 -2.5 -0.7 -0.8 0.3 -1.5 -1.1 -0.6 0.1
Arm fat mass (left) 0.2 0.9 2.5 -1.3 -0.9 -0.4 -1.6 -1.5 -0.1 0.1 0.2
Number of self-reported non-cancer illnesses 0.9 1.5 3.8 -0.1 -0.3 1.9 -0.0 1.0 1.6 1.6 1.6
Average weekly champagne plus white wine intake 1.2 1.7 6.2 -1.1 -0.4 -0.5 1.8 -0.1 -1.0 -2.5 -1.0
Miserableness 0.3 0.4 1.3 0.3 -1.1 1.0 0.6 -0.3 0.8 -0.2 0.2
Guilty feelings 0.4 0.6 3.3 -0.7 0.2 -0.7 -0.1 -1.8 -0.6 -0.5 -0.5
Wears glasses or contact lenses 0.7 0.8 2.2 0.2 0.6 0.7 1.5 1.1 0.8 1.0 0.6
Ever taken oral contraceptive pill 0.1 0.2 0.6 -0.1 -0.1 -0.0 0.8 0.7 0.2 -0.1 -0.2
Hearing aid user 0.4 0.4 1.5 -0.9 -0.0 -0.5 0.4 0.0 -0.7 -1.2 -0.2
Mother’s age at death 0.4 0.4 1.0 0.2 -0.8 -0.9 0.4 -0.2 -1.0 -0.7 -0.7
Financial situation satisfaction 0.9 1.2 2.5 -1.5 -0.1 -0.9 -0.9 -0.4 -1.4 -1.6 -1.0
Tinnitus: Yes, now most or all of the time 2.3 2.6 6.1 -1.0 -2.2 -1.5 1.5 -0.6 -2.1 -2.5 0.3
Commuting to job workplace: Public transport 0.2 0.3 0.9 -0.2 0.1 0.1 -0.8 -0.6 -0.5 -0.9 0.3
Eye problems/disorders: Glaucoma 0.3 0.3 0.9 0.9 -0.4 0.3 -0.1 -0.5 0.4 0.6 -0.9
Medication: Blood pressure 0.7 1.3 3.2 -0.3 0.6 1.4 1.5 0.7 1.2 1.8 1.0
Pain type(s) experienced in last month: Hip pain 0.7 0.9 2.2 0.1 -0.2 1.5 -1.0 -0.1 1.1 1.2 1.0
Supplements: Fish oil (including cod liver oil) 1.0 1.3 3.2 -1.2 1.3 1.4 -1.3 1.8 0.5 -0.0 -0.6
High cholesterol (Self-reported) 0.7 1.2 3.7 0.1 0.8 0.1 1.3 1.9 0.3 0.7 1.7
Medication: Bendroflumethiazide 0.1 0.2 1.1 -1.0 0.0 -0.1 -0.1 -0.7 0.1 0.2 -0.3
Medication: Paracetamol 0.1 0.2 0.7 0.3 -0.5 0.5 -0.8 0.7 -0.1 0.0 -0.3
Medication: Lisinopril 1.9 2.4 7.3 -0.8 1.9 1.4 1.8 0.5 1.2 2.7 1.0
Medication: Atorvastatin 0.5 0.7 3.8 0.7 0.1 0.2 2.0 0.7 0.6 0.2 0.0
Illnesses of father: High blood pressure 0.5 0.6 1.4 0.8 -1.0 -0.5 0.1 0.1 -0.9 -1.2 -0.8
Alcohol drinker status: Never 0.2 0.2 0.6 -0.0 -0.6 -0.2 -0.8 -0.1 -0.2 0.1 -0.7
Ever smoked 0.4 0.7 2.8 0.5 -1.2 -0.5 1.7 0.3 -0.6 -0.8 -0.0
Basal metabolic rate 0.3 1.5 6.8 -2.6 -0.7 -1.0 0.4 -1.1 -1.1 -1.1 -0.4
Leg fat percentage (left) 0.3 1.1 3.5 -0.2 -0.5 0.6 -1.9 -0.6 1.2 1.5 1.0
Arm fat-free mass (left) 0.4 2.3 5.3 -2.3 -1.3 -1.3 0.6 -1.5 -1.5 -1.8 -1.0
Number of operations (self-reported) 0.5 0.7 2.8 1.2 -1.7 -0.8 0.2 -0.2 -0.1 -0.3 -0.7
Average weekly beer plus cider intake 1.0 1.4 3.8 -0.7 0.1 1.2 0.1 0.9 1.3 1.9 1.7
Irritability 1.1 1.8 4.6 2.1 -1.2 -1.0 -0.4 -1.3 -1.3 -1.4 -1.3
Risk taking 0.9 1.4 5.5 -0.3 0.4 1.1 1.8 2.3 0.8 0.0 0.2
Ever had prostate specific antigen (PSA) test 2.3 2.6 5.9 -2.4 1.2 -1.2 -2.3 0.2 -1.5 -2.0 -0.8
Fractured/broken bones in last 5 years 0.1 0.1 0.3 -0.3 -0.4 -0.0 -0.5 -0.1 -0.3 0.3 0.4
Age started oral contraceptive pill 0.5 0.7 1.7 -1.2 1.0 0.1 0.0 1.3 -0.6 -0.5 -0.7
Diastolic blood pressure, automated reading 0.2 0.7 1.7 0.6 -1.3 -0.1 -0.5 1.3 -1.0 -0.8 0.3
Ever depressed for a whole week 1.6 1.9 3.8 -1.0 -1.0 -1.9 0.7 -1.0 -1.9 -2.0 -0.9
Unable to work because of sickness or disability 0.7 0.9 1.8 1.4 -1.3 0.4 0.6 -1.1 0.6 1.2 0.8
Commuting to job workplace: Cycle 0.8 1.0 2.2 0.5 0.2 0.8 -0.6 -0.9 1.2 1.3 1.5
Myopia 0.2 0.3 2.3 -0.2 -0.1 -0.1 -0.1 1.5 0.1 -0.2 -0.2
Vascular/heart problems diagnosed by doctor 0.5 1.4 3.4 -0.5 1.8 -0.9 -1.7 -1.8 -0.2 -0.5 -0.0
Cholesterol lowering medication 0.2 0.3 1.2 0.5 -1.1 -0.3 0.9 0.5 -0.1 -0.2 0.0
Medication: Omeprazole (e.g. Zanprol) 0.1 0.2 0.7 -0.4 -0.1 -0.0 0.5 -0.3 0.2 0.8 0.3
Pain experienced in last month 0.5 0.8 2.6 0.7 -0.1 -1.6 0.7 -0.2 -1.4 -0.8 -0.4
Supplements: Calcium 0.5 0.6 1.4 1.2 -1.1 -0.4 -0.9 -0.1 0.1 0.2 -0.8
Basal cell carcinoma (self-reported) 2.8 3.4 8.4 -1.6 -0.3 -2.7 -0.9 -0.5 -2.2 -1.6 -2.9
Heart attack/myocardial infarction (self-reported) 1.6 2.0 4.8 -0.6 -2.2 -1.3 -0.1 -0.6 -1.9 -1.8 -1.4
Deep venous thrombosis (DVT) (self-reported) 0.5 0.6 4.0 2.0 0.7 -0.3 0.1 -0.2 0.3 -0.4 0.3
Heart disease (siblings) 1.0 1.2 2.5 1.1 -0.7 0.6 1.6 1.2 0.8 0.9 1.6
Alcohol drinker status: Previous 0.6 0.7 2.3 -0.7 -0.4 0.5 -1.5 0.5 0.2 0.2 1.4
Pack years of smoking 0.7 1.0 3.0 0.2 -0.5 1.5 0.9 1.7 1.1 0.6 0.6
Impedance of whole body 1.4 7.2 16.1 3.7 0.0 2.3 3.3 4.0 2.5 2.4 0.6
Leg fat mass (left) 0.2 1.0 2.3 -1.3 -0.8 0.4 -1.5 -0.9 0.7 1.0 0.8
Arm predicted mass (left) 0.4 2.1 5.7 -2.4 -1.0 -1.2 0.4 -1.4 -1.5 -1.7 -1.0