Hub : Genes

ZNF767

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1480	0.0330	2.7e-11	0.085	0.089	0.109	0.102	0.104	1.5e-10	5.7e-11	3.2e-13	2.3e-12	1.3e-12
2	GTEx	Artery Tibial	0.1132	0.0366	1.8e-04	0.006	NA	0.023	NA	0.030	1.0e-01	NA	6.4e-03	NA	2.0e-03
3	GTEx	Colon Transverse	0.1850	0.0600	2.2e-04	0.104	NA	0.069	NA	0.082	1.2e-05	NA	3.4e-04	NA	1.0e-04
4	GTEx	Esophagus Muscularis	0.1090	0.0480	5.5e-03	0.001	NA	0.005	NA	0.001	2.8e-01	NA	1.6e-01	NA	2.6e-01
5	GTEx	Nerve Tibial	0.1667	0.0573	5.0e-04	0.053	NA	0.037	NA	0.047	1.3e-04	NA	1.1e-03	NA	2.9e-04
6	GTEx	Skin Sun Exposed Lower leg	0.1010	0.0340	3.2e-04	0.009	NA	0.006	NA	0.020	5.2e-02	NA	8.9e-02	NA	8.4e-03
7	GTEx	Spleen	0.3290	0.0940	2.4e-04	0.076	NA	0.055	NA	0.091	5.5e-03	NA	1.6e-02	NA	2.5e-03
8	GTEx	Stomach	0.1500	0.0590	3.2e-03	0.093	NA	0.004	NA	0.054	3.4e-05	NA	2.0e-01	NA	1.4e-03
9	GTEx	Thyroid	0.1140	0.0360	6.9e-05	0.132	NA	0.122	NA	0.127	2.6e-10	NA	1.4e-09	NA	6.4e-10
10	GTEx	Whole Blood	0.0680	0.0300	4.6e-03	0.015	NA	0.003	NA	0.007	1.3e-02	NA	1.7e-01	NA	6.2e-02
11	ROSMAP	Brain Pre-frontal Cortex	0.0704	0.0253	1.2e-04	0.010	0.021	0.006	0.019	0.008	1.5e-02	8.0e-04	4.4e-02	1.4e-03	2.5e-02
12	TCGA	Cervical Squamous Cell Carcinoma	0.0540	0.0340	9.5e-03	0.019	0.019	0.023	NA	0.025	3.8e-02	3.8e-02	2.6e-02	NA	2.1e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Bipolar Disorder (2018)	0.2	0.3	2.1	-0.0	0.8	-0.1	-0.5	-0.3	-0.0	-0.5	-0.2	-0.2	0.4	-1.5	-0.5
Bipolar Disorder or Schizophrenia	0.2	0.4	2.4	-1.1	0.4	-0.3	-0.5	-0.3	0.4	-0.1	-0.2	-0.2	-0.1	-1.6	-0.5
Depressed Affect (Nagel 2018)	0.5	1.0	3.9	-0.5	0.0	-0.8	-1.1	-1.0	-1.2	-0.5	-1.0	-1.0	2.0	-0.1	-1.1
Depression (Nagel 2018)	0.4	0.6	1.8	-0.7	0.4	-0.6	-0.9	-0.8	-0.5	-0.1	-0.7	-0.7	1.4	-1.1	-0.9
Intelligence (Savage-Jansen 2018)	1.9	6.0	15.0	2.4	0.7	2.8	2.7	2.4	2.3	2.0	2.3	2.1	-3.9	2.4	2.3
Neuroticism (Nagel 2018)	0.4	0.9	1.9	-0.3	1.2	0.9	0.8	0.9	0.1	1.3	0.9	0.8	1.4	1.3	0.8
Schizophrenia (2018)	0.1	0.3	1.8	-1.3	-0.2	-0.4	-0.2	-0.2	0.6	0.4	-0.1	-0.1	-0.5	-0.8	-0.2
Schizophrenia vs Biploar Disorder	0.5	0.6	1.4	0.2	0.5	0.9	1.1	0.9	0.8	0.6	0.8	0.7	-0.4	1.2	1.0
Worry (Nagel 2018)	2.0	4.2	7.1	0.1	2.1	2.5	2.3	2.4	1.5	2.7	2.3	2.3	-0.3	1.7	2.3
Alzheimer’s Disease (in mother)	0.6	0.7	2.9	-0.1	-0.9	-0.8	-0.8	-0.7	-0.9	-0.6	-0.7	-0.7	0.7	-1.7	-0.7
Alzheimer’s Disease (in father)	0.1	0.2	0.4	-0.4	-0.1	-0.2	-0.4	-0.5	-0.3	-0.6	-0.4	-0.4	0.3	0.0	-0.7
Alzheimer’s Disease (including proxy)	0.4	0.6	2.5	-0.2	-0.7	-0.8	-0.7	-0.7	-0.7	-0.7	-0.9	-0.7	0.5	-1.6	-0.7
Crohns Disease (2017)	3.4	7.5	15.9	3.3	-4.0	-2.9	-2.8	-2.9	-2.4	-2.9	-2.9	-2.9	-0.7	0.2	-2.6
Irritable Bowel Disease (IBD)	1.0	2.3	6.6	2.6	-2.1	-1.3	-1.4	-1.5	-1.3	-1.2	-1.5	-1.5	-0.4	0.8	-1.5
Ulcerative Colitis (UC)	0.2	0.3	1.8	1.4	0.2	0.5	0.2	0.0	0.1	0.4	0.1	0.1	-0.0	1.1	-0.1
Major Depression (MDD)	4.3	5.3	10.7	0.8	2.4	2.4	2.3	2.4	2.4	3.3	2.5	2.4	-1.0	2.2	2.4
Reaction Time	1.1	2.2	3.0	-0.4	1.7	1.7	1.6	1.6	1.7	1.4	1.6	1.6	0.1	1.7	1.5
Verbal and Numeric Reasoning (VNR)	0.9	2.2	8.6	2.5	-0.5	1.2	1.1	1.0	1.4	0.6	1.1	1.1	-2.9	1.5	1.0
Breast Cancer	0.3	0.7	1.4	0.7	-1.0	-1.2	-1.0	-1.0	-0.4	-0.4	-0.9	-0.9	0.0	0.4	-1.0
Ovarian Cancer	0.4	0.6	1.9	0.9	-1.4	-0.7	-0.4	-0.5	-1.0	-0.8	-0.6	-0.6	-0.1	0.7	-0.5
Prostate Cancer	0.0	0.0	0.1	-0.4	-0.2	-0.3	-0.3	-0.2	-0.2	-0.2	-0.1	-0.1	-0.0	0.2	-0.2
Age at First Birth	0.1	0.2	0.6	0.5	-0.1	0.2	-0.2	-0.2	-0.7	-0.8	-0.2	-0.2	-0.6	0.2	-0.4
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	1.0	1.3	5.9	-1.1	0.3	-0.9	-0.9	-1.0	-1.0	-0.8	-0.9	-1.0	2.4	-1.4	-1.1
Coronary Artery Disease (CAD)	0.3	0.3	2.4	1.5	-0.1	0.1	0.1	-0.2	0.0	-0.5	-0.1	-0.3	-0.6	-0.9	-0.4
Crohns Disease (2012)	5.2	8.4	12.8	3.1	-3.6	-3.3	-3.0	-3.1	-3.2	-3.2	-3.3	-3.2	0.6	-0.1	-2.9
Mean Putamen Volume	0.3	0.3	0.9	-1.0	-0.1	-0.3	-0.5	-0.5	-0.6	-0.9	-0.5	-0.5	0.4	-0.5	-0.6
Fasting Glucose	0.3	0.3	2.0	0.2	-0.4	-0.8	-0.5	-0.5	0.2	-0.1	-0.6	-0.6	0.1	-1.4	-0.3
HbA1C	0.8	0.9	1.9	-0.3	0.7	1.0	1.2	1.4	0.8	0.5	1.2	0.9	-0.1	0.8	1.4
HDL Cholesterol	1.0	1.7	2.8	0.4	0.8	1.7	1.6	1.6	0.3	1.2	1.6	1.5	-1.5	0.9	1.5
LDL Cholesterol	1.1	1.8	13.3	-3.6	1.6	0.1	0.3	0.4	-0.4	0.6	0.4	0.3	2.0	-0.5	0.2
Lupus	2.2	3.4	7.1	0.7	-1.6	-1.8	-2.0	-2.2	-1.2	-2.7	-2.3	-2.3	-0.1	-1.5	-2.1
Neuroticism (2016)	1.0	1.4	3.1	-1.4	1.8	1.0	1.1	1.1	1.2	1.4	1.1	1.1	0.9	0.3	1.3
Primary Biliary Cirrhosis	0.3	0.4	2.0	-0.7	0.5	-0.2	-0.4	-0.4	-0.4	-0.0	-0.3	-0.3	0.9	-1.4	-0.4
Rheumatoid Arthritis	1.5	2.1	3.3	0.4	-1.7	-1.8	-1.4	-1.4	-1.8	-1.0	-1.4	-1.4	1.6	-1.3	-1.3
Schizophrenia (2014)	0.4	0.9	3.1	0.1	-1.3	-1.2	-1.1	-1.0	-0.4	-0.4	-0.8	-0.9	-0.3	-1.8	-1.0
Triglycerides	1.0	1.7	7.6	-2.5	0.2	-1.1	-0.5	-0.8	-1.2	-0.2	-0.8	-0.8	2.8	-1.0	-0.8
Type 2 Diabetes (T2D) (2012)	0.3	0.4	2.1	-0.7	0.8	-0.0	0.0	-0.1	0.6	-0.6	-0.6	-0.2	1.4	-0.4	-0.3
Ulcerative Colitis	0.3	0.4	1.2	0.7	-0.4	-0.5	-0.6	-0.7	-1.1	-0.4	-0.6	-0.7	0.6	-0.4	-0.8
Blood Eosinophil Count	0.4	2.8	26.7	-2.2	0.7	0.4	0.3	0.2	-0.6	-0.9	0.2	0.1	-0.5	5.2	0.2
Blood Platelet Count	0.1	1.3	8.3	2.2	0.1	0.6	0.6	0.4	0.5	-0.2	0.4	0.4	-0.6	2.9	0.4
Blood Red Count	0.4	3.9	8.6	2.9	-2.5	-2.3	-2.2	-2.0	-1.3	-1.5	-2.0	-2.1	0.3	-1.4	-2.0
Blood White Count	0.5	3.5	15.5	-3.9	1.9	-0.5	-0.4	-0.4	0.2	0.6	-0.3	-0.4	2.9	-3.6	-0.4
Heel T-Score	0.1	1.0	1.6	0.8	-1.1	-0.9	-1.0	-1.2	-0.3	-1.2	-1.1	-1.2	-1.3	-0.3	-1.1
BMI	0.3	1.5	5.8	-1.3	0.7	-1.0	-0.8	-0.9	-0.5	-0.5	-0.9	-0.8	2.4	-2.2	-0.9
Height	0.3	6.4	16.7	2.2	-3.8	-2.6	-2.3	-2.5	-4.1	-1.7	-2.4	-2.4	0.5	-0.7	-2.7
Waist Hip Ratio (WHR)	0.2	1.0	6.8	-2.6	1.2	0.1	0.2	0.5	0.6	0.5	0.4	0.4	1.2	0.5	0.6
Systolic Blood Pressure	0.2	1.2	5.1	-1.6	-0.3	-1.0	-0.8	-0.8	0.4	-0.7	-0.9	-0.9	1.3	-2.3	-0.5
Smoking Status	0.6	1.4	5.8	-0.3	-0.4	-1.1	-1.0	-0.9	-1.2	-0.1	-0.9	-0.9	1.9	-2.4	-0.8
Allergy or Eczema	1.2	3.1	6.9	2.6	-2.2	-1.1	-1.6	-1.6	-2.1	-2.1	-1.6	-1.5	-1.4	-0.5	-1.8
Cardiovascular Disease	0.3	0.9	4.8	-0.6	1.2	0.1	0.0	0.0	0.3	0.6	0.1	0.1	2.0	-2.2	-0.0
Hypothyroidism (self reported)	1.1	2.5	6.7	-0.1	2.5	1.7	1.3	1.2	1.9	2.6	1.3	1.3	0.3	-1.6	1.2
Respiratory disease	1.3	2.8	3.7	-0.4	-1.7	-1.9	-1.9	-1.8	-1.9	-1.9	-1.8	-1.8	0.6	-1.6	-1.9
Type 2 Diabetes (T2D) (2018)	1.1	2.0	11.6	-3.2	1.0	-0.5	-0.0	0.1	-0.9	0.4	0.2	0.2	3.4	-0.9	-0.1
Lung FEV1/FVC ratio	0.3	1.5	2.8	0.7	-1.2	-1.2	-1.4	-1.4	-0.6	-1.7	-1.4	-1.5	0.3	-1.4	-1.2
Lung FVC	0.4	1.9	2.6	1.6	-1.6	-1.4	-1.5	-1.5	-1.0	-1.4	-1.5	-1.5	0.2	1.0	-1.6
Neuroticism	0.8	2.0	4.1	-1.0	2.0	1.4	1.4	1.5	0.4	2.0	1.4	1.4	1.5	0.9	1.4
Chronotype (morning person)	0.8	1.9	9.6	-1.5	2.1	0.1	0.1	0.4	-0.2	1.9	0.3	0.3	3.1	-1.4	0.2
Hair Pigment	0.0	0.2	1.3	1.1	-0.3	0.3	0.4	0.1	-0.2	-0.1	0.4	0.3	-0.2	0.3	-0.4
Tanning	0.1	0.6	1.4	1.2	-1.2	-0.8	-0.7	-0.6	-0.7	-0.7	-0.7	-0.6	-0.6	-0.7	-0.6
Hand grip strength (left)	0.5	1.2	6.9	2.6	-1.1	-0.3	-0.5	-0.4	-0.8	-0.3	-0.2	-0.2	-1.8	1.1	-0.8
Number of treatments/medications taken	0.3	0.5	3.0	-1.5	0.0	-0.3	-0.3	-0.2	-0.2	-0.2	-0.2	-0.2	0.4	-1.7	-0.2
Average weekly spirits intake	0.1	0.1	0.9	-0.4	0.2	-0.1	-0.1	-0.1	-0.4	-0.4	-0.0	0.0	0.2	-1.0	-0.2
Sensitivity / hurt feelings	0.1	0.2	1.5	0.1	0.2	-0.6	-0.3	-0.2	-0.6	0.4	-0.2	-0.2	1.2	-0.6	-0.0
Frequency of depressed mood in last 2 weeks	0.6	0.9	1.6	0.8	-0.3	-1.0	-1.1	-1.0	-0.5	-0.6	-1.1	-1.0	1.2	-1.1	-1.0
Hearing difficulty/problems: Yes	2.2	3.3	5.6	-1.3	1.4	1.8	1.9	2.0	2.4	1.9	2.0	2.0	-1.0	1.8	2.0
Relative age of first facial hair	0.1	0.1	0.6	-0.6	-0.2	-0.2	0.3	0.2	0.0	0.1	0.2	0.2	0.2	0.8	0.2
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	2.7	-1.0	0.9	0.2	-0.2	-0.2	-0.1	0.2	-0.1	-0.1	1.6	-0.6	-0.2
Ever used hormone-replacement therapy (HRT)	2.1	2.7	5.1	0.5	-2.2	-2.0	-1.9	-1.8	-1.2	-2.3	-1.9	-1.9	-0.4	0.0	-1.6
Ever had hysterectomy (womb removed)	0.3	0.4	1.3	0.3	0.1	-0.5	-0.7	-0.6	0.3	-0.1	-0.7	-0.7	0.9	-1.1	-0.5
Systolic blood pressure, automated reading	0.2	0.5	1.5	-1.1	-0.5	-0.7	-0.4	-0.5	0.6	-0.8	-0.6	-0.6	0.4	-1.2	-0.3
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.5	-0.7	-0.1	-0.0	0.3	0.2	0.1	-0.3	0.3	0.2	0.3	0.3	0.1
Angina	0.1	0.2	0.6	-0.4	-0.4	-0.5	-0.2	-0.2	-0.3	-0.2	-0.1	-0.2	0.8	-0.6	-0.2
Medication for hormone replacement therapy	0.2	0.2	0.9	0.3	-0.5	-0.1	-0.1	-0.2	-0.3	-0.5	-0.2	-0.2	-0.9	0.8	-0.2
Vitamin and mineral supplements	3.9	5.4	8.6	-0.4	2.2	2.3	2.6	2.7	2.9	2.8	2.6	2.6	-1.1	1.1	2.8
Supplements: Zinc	2.3	2.5	4.5	0.2	-1.4	-1.6	-1.6	-1.9	-1.9	-2.1	-1.8	-1.8	1.0	-0.2	-2.0
Medication: Co-codamol	0.1	0.1	1.0	1.0	-0.3	0.3	-0.1	-0.1	0.3	0.1	-0.1	-0.1	-0.7	-0.0	0.0
Medication: Metformin	0.9	1.2	7.7	-2.3	0.9	-0.1	0.1	0.0	-0.9	0.3	0.1	0.0	2.8	-0.3	-0.2
Diabetes (father)	0.3	0.4	0.8	0.2	0.5	0.8	0.8	0.6	0.7	0.9	0.6	0.6	-0.5	0.4	0.6
Diabetes (mother)	0.4	0.5	2.4	-1.6	-0.1	-0.4	-0.4	-0.3	-1.2	-0.3	-0.3	-0.3	0.8	-0.4	-0.4
Severe depression (siblings)	0.5	0.5	0.8	0.5	-0.9	-0.8	-0.8	-0.7	-0.8	-0.9	-0.7	-0.7	0.3	-0.7	-0.7
Pack years adult smoking proportion	1.8	2.8	5.3	-0.5	2.1	1.8	1.8	1.8	2.0	2.3	1.7	1.7	-0.2	0.5	2.0
Impedance of leg (right)	0.2	0.9	5.1	-2.3	-0.4	-0.6	-0.6	-0.6	-1.6	-0.7	-0.6	-0.7	0.8	-0.2	-0.6
Leg fat-free mass (left)	0.2	1.2	4.2	2.0	-1.0	-1.1	-0.9	-1.0	-1.1	-0.3	-0.9	-0.9	0.7	-1.1	-1.1
Trunk fat percentage	0.8	3.3	10.4	-2.5	0.3	-1.5	-1.4	-1.5	-1.3	-1.0	-1.6	-1.5	2.6	-3.2	-1.3
Hand grip strength (right)	0.5	1.3	6.6	2.6	-1.0	0.1	-0.1	-0.1	-0.8	0.5	0.2	0.1	-2.1	1.5	-0.5
Townsend deprivation index at recruitment	0.5	0.7	3.4	1.8	-1.0	-0.6	-0.6	-0.6	-0.9	-0.3	-0.6	-0.6	0.0	-0.2	-0.7
Current tobacco smoking	0.1	0.2	0.7	-0.8	0.8	0.1	-0.0	0.0	-0.4	0.4	0.0	-0.0	0.8	-0.1	0.1
Average weekly fortified wine intake	0.8	0.9	2.8	1.7	-1.7	-0.8	-0.9	-0.8	0.0	-0.8	-0.7	-0.7	-0.9	-0.6	-0.8
Maternal smoking around birth	0.7	1.1	2.7	0.1	1.6	1.4	1.2	0.9	1.0	1.4	0.8	0.9	0.6	0.1	0.9
Fed-up feelings	0.6	1.0	1.7	0.7	-0.9	-1.3	-1.2	-1.1	-1.0	-0.5	-1.2	-1.2	1.2	-0.4	-1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.3	0.1	-0.5	-1.0	-0.8	-0.6	-0.4	-0.1	-0.6	-0.6	1.1	-0.3	-0.6
Relative age voice broke	0.3	0.4	1.8	-1.3	0.8	0.4	0.6	0.5	0.4	0.4	0.6	0.5	-0.0	-0.6	0.4
Taking other prescription medications	0.1	0.1	1.2	-1.1	0.3	0.1	0.0	0.1	0.4	0.3	0.1	0.2	0.1	-0.2	0.2
Age when periods started (menarche)	0.5	1.2	8.2	-1.5	0.6	-0.5	-0.4	-0.3	-1.4	-0.0	-0.4	-0.4	2.9	-0.6	-0.4
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	2.4	-1.5	1.4	0.9	0.8	1.0	1.0	0.5	0.8	0.9	0.1	0.4	1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.5	-0.2	-0.7	-0.6	-0.5	-0.6	-0.2	-0.7	-0.7	-0.6	-0.7	-0.6	-0.6
Tinnitus: Yes, but not now, but have in the past	2.5	2.7	4.5	0.6	-1.4	-2.0	-1.9	-2.0	-0.4	-1.6	-2.1	-2.1	-0.4	-2.1	-1.6
Qualifications: CSEs or equivalent	1.9	2.5	4.0	0.1	-1.3	-1.7	-1.8	-1.9	-1.5	-1.2	-1.9	-1.9	0.8	-1.8	-2.0
Serious illness, injury or assault to yourself	0.4	0.4	1.5	0.5	0.8	-0.2	-0.8	-0.7	-0.0	0.0	-0.7	-0.6	0.6	-1.2	-0.7
High blood pressure	0.3	0.7	3.6	-1.4	0.8	-0.4	-0.4	-0.4	0.7	-0.1	-0.4	-0.4	1.1	-1.9	-0.3
Hayfever, allergic rhinitis or eczema	1.9	4.1	9.0	3.0	-2.6	-1.6	-2.0	-2.0	-2.3	-2.1	-1.9	-1.9	-0.5	-0.8	-2.2
Multivitamins +/- minerals	0.9	1.1	2.2	0.1	-0.8	-0.8	-1.1	-1.2	-1.5	-1.3	-1.2	-1.2	0.8	-0.3	-1.3
Stomach or abdominal pain in last month	2.7	3.4	7.3	-1.6	-0.7	-1.8	-1.7	-1.8	-2.0	-0.9	-1.8	-1.8	2.7	-2.7	-1.7
Supplements: Glucosamine	1.5	2.0	4.4	-0.7	-1.6	-1.4	-1.5	-1.4	-2.1	-1.9	-1.5	-1.5	0.7	0.2	-1.4
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	1.0	-0.2	0.8	0.5	0.3	0.2	0.4	0.4	0.1	0.1	1.0	0.5	0.3
Medication: Atenolol	0.3	0.4	0.9	0.2	0.3	0.5	0.5	0.6	0.6	0.4	0.7	0.7	-0.8	-0.9	0.7
Medication: Levothyroxine sodium	0.4	0.7	2.6	0.3	1.3	0.6	0.3	0.3	1.2	1.2	0.3	0.3	0.6	-1.6	0.1
Sitting height	0.8	5.6	13.0	3.4	-3.6	-2.3	-2.0	-2.1	-3.5	-1.4	-2.0	-2.0	-0.2	-1.4	-2.3
Chronic bronchitis/emphysema (father)	0.4	0.4	1.5	-0.4	1.2	0.8	0.6	0.6	0.6	0.4	0.7	0.7	-0.3	0.5	0.5
High blood pressure (mother)	0.2	0.2	0.7	-0.5	0.6	-0.1	-0.3	-0.3	-0.3	0.4	-0.4	-0.4	0.7	-0.9	-0.0
Body mass index (BMI)	0.8	3.3	8.6	-1.0	-0.2	-1.8	-1.7	-1.8	-1.1	-1.2	-1.9	-1.8	2.9	-2.9	-1.7
Impedance of leg (left)	0.2	1.0	3.4	-1.8	-0.7	-0.7	-0.8	-0.8	-1.9	-1.0	-0.8	-0.9	0.6	-0.4	-0.7
Leg predicted mass (left)	0.2	1.2	4.2	2.0	-0.9	-1.1	-0.9	-1.0	-1.1	-0.3	-1.0	-0.9	0.8	-1.1	-1.2
Trunk fat mass	0.9	3.9	10.2	-1.2	-0.6	-2.0	-1.9	-2.0	-1.8	-1.4	-2.0	-2.0	2.5	-3.2	-2.0
Waist circumference	0.7	2.5	6.7	-1.1	-0.3	-1.8	-1.5	-1.5	-0.7	-1.1	-1.6	-1.6	2.6	-2.4	-1.4
Number of incorrect matches in round	0.9	1.5	5.7	-1.2	-1.0	-1.3	-1.0	-1.1	-0.4	-1.5	-1.1	-1.1	0.3	-2.4	-1.1
Past tobacco smoking	0.6	1.2	4.5	0.6	0.3	1.0	1.0	0.7	1.4	0.0	0.7	0.6	-2.1	1.9	0.7
Alcohol usually taken with meals	0.2	0.4	3.1	-0.5	-0.6	-0.1	-0.1	-0.1	-0.7	0.1	-0.3	-0.2	-0.1	-1.8	-0.1
Nervous feelings	2.3	4.2	5.9	1.4	1.1	2.1	2.2	2.3	2.0	2.3	2.2	2.2	-1.7	2.3	2.4
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	1.1	0.3	-0.7	-1.0	-1.0	-0.9	-0.6	-0.5	-0.9	-0.9	0.5	-0.4	-0.7
Hearing difficulty/problems with background noise	0.1	0.2	0.7	-0.8	-0.9	-0.4	0.2	0.4	0.3	0.5	0.4	0.4	-0.3	-0.5	0.3
Hair/balding pattern: Pattern 2	10.1	12.9	26.1	2.2	-5.1	-4.7	-4.0	-3.8	-3.3	-4.1	-3.8	-3.8	0.8	-1.4	-3.7
Had menopause	0.1	0.2	1.2	0.3	0.0	0.0	0.1	0.2	0.6	0.0	0.2	0.2	-1.1	-0.3	0.1
Had other major operations	0.6	0.7	3.5	-0.2	-0.6	-0.9	-0.9	-0.8	-0.6	-0.5	-0.7	-0.7	0.5	-1.9	-0.7
Forced vital capacity (FVC)	1.3	5.2	10.6	2.7	-3.2	-2.4	-2.3	-2.2	-2.8	-2.2	-2.2	-2.2	0.1	0.0	-2.4
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	2.3	-0.2	-1.1	-1.1	-1.1	-1.2	-0.9	-1.5	-1.3	-1.2	-0.2	-1.0	-1.2
Ever unenthusiastic/disinterested for a whole week	1.0	1.3	2.9	-0.5	-0.1	-1.1	-1.4	-1.2	-0.9	-0.5	-1.1	-1.1	1.5	-1.7	-1.2
Qualifications: None of the above	0.6	1.2	3.1	-1.4	1.8	0.6	0.8	1.0	1.6	0.9	0.8	0.8	0.9	0.4	1.3
Financial difficulties in last 2 years	1.9	2.5	3.6	1.9	-1.2	-1.4	-1.7	-1.7	-1.5	-1.1	-1.9	-1.9	1.2	-1.5	-1.6
Mouth/teeth dental problems	0.2	0.3	1.5	-0.2	-0.6	-0.4	-0.4	-0.2	-1.2	-0.1	-0.1	-0.1	0.4	1.0	-0.5
Heart attack	0.1	0.2	0.9	-0.0	-0.4	-0.2	0.1	0.2	-0.3	0.6	0.2	0.2	1.0	-0.0	0.3
Allergy	1.4	3.3	7.6	-2.8	2.2	1.4	1.9	1.8	2.0	1.8	1.7	1.7	0.7	0.8	2.0
Pain all over the body in last month	1.6	1.7	4.6	1.5	-2.1	-1.5	-1.3	-1.3	-1.0	-1.2	-1.3	-1.3	-0.8	-0.8	-1.2
Diabetes (self-reported)	1.0	1.5	7.3	-2.3	0.4	-0.9	-0.5	-0.5	-1.3	-0.4	-0.4	-0.4	2.7	-1.2	-0.7
Hayfever/allergic rhinitis (self-reported)	1.3	1.8	5.0	2.2	-1.7	-1.0	-1.3	-1.3	-1.1	-1.5	-1.2	-1.2	-0.9	-0.2	-1.3
Medication: Ramipril	1.1	1.4	3.9	-2.0	1.8	1.1	1.0	0.8	1.8	0.9	0.8	0.9	0.2	-0.0	1.0
Medication: Simvastatin	1.6	2.4	5.9	-2.3	2.4	1.0	1.2	1.3	1.2	1.5	1.3	1.3	1.5	-1.3	1.4
Fluid intelligence score	0.4	0.8	3.5	1.9	-0.2	0.8	0.6	0.7	0.6	0.6	0.7	0.7	-1.3	1.0	0.7
Illnesses of siblings	1.4	1.9	3.0	-0.6	1.5	1.7	1.7	1.6	1.3	1.2	1.5	1.5	-0.6	1.0	1.7
Neuroticism score	0.5	0.9	3.0	0.3	1.1	0.8	0.9	1.0	0.6	1.7	0.9	0.9	0.9	0.7	1.2
Weight	1.0	5.0	8.1	0.6	-1.6	-2.5	-2.3	-2.5	-2.2	-1.7	-2.5	-2.4	2.3	-2.8	-2.5
Impedance of arm (right)	0.2	0.7	1.4	-1.1	0.8	1.0	0.8	0.9	0.3	0.6	0.9	0.9	-1.2	0.5	0.9
Arm fat percentage (right)	0.8	3.1	10.6	-1.4	0.3	-1.5	-1.5	-1.6	-1.1	-1.2	-1.7	-1.7	2.6	-3.2	-1.5
Trunk fat-free mass	0.7	4.0	9.7	3.1	-2.4	-2.0	-1.9	-2.0	-2.2	-1.4	-2.0	-1.9	0.8	-1.0	-2.4
Hip circumference	1.0	4.2	9.0	0.7	-1.3	-2.3	-2.0	-2.2	-1.7	-1.5	-2.2	-2.2	2.3	-3.0	-2.2
Time employed in main current job	0.3	0.4	1.9	0.3	-0.2	0.4	0.5	0.4	-0.2	-0.2	0.4	0.4	-1.1	1.4	0.4
Alcohol intake versus 10 years previously	3.9	5.8	14.7	-1.1	-1.0	-2.6	-2.6	-2.6	-2.4	-1.7	-2.6	-2.6	2.3	-3.8	-2.4
Father’s age at death	0.1	0.2	0.7	0.1	-0.8	-0.5	-0.2	-0.2	-0.6	-0.5	-0.2	-0.2	-0.0	0.3	-0.3
Worrier / anxious feelings	0.4	0.7	1.6	1.0	-0.7	-0.8	-0.9	-0.8	-0.5	-0.8	-0.8	-0.9	0.3	1.3	-0.7
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.2	-0.0	-0.9	-0.7	-0.8	-0.9	-0.6	-0.9	-1.0	-1.1	0.3	-1.5	-0.8
Falls in the last year	0.1	0.1	1.2	-1.1	-0.0	0.1	0.1	-0.0	0.2	-0.1	-0.1	-0.1	0.0	-0.0	0.2
Hair/balding pattern: Pattern 3	2.3	3.4	4.8	-0.3	2.0	2.2	2.0	1.9	2.1	2.1	1.9	1.9	-0.8	2.0	2.0
Number of live births	2.3	3.2	7.4	-2.3	2.7	2.1	1.7	1.7	2.0	1.6	1.7	1.8	-0.3	0.5	1.7
Forced expiratory volume in 1-second (FEV1)	1.4	4.6	9.4	2.7	-3.1	-2.1	-2.1	-2.1	-2.7	-2.2	-2.0	-2.0	-0.2	0.2	-2.2
Pulse rate	2.6	4.4	13.8	-2.3	0.3	-1.7	-1.6	-1.6	-2.1	-0.3	-1.7	-1.7	3.5	-3.7	-1.7
Happiness	2.9	3.5	4.5	0.6	1.4	2.1	2.0	2.1	2.0	2.1	2.1	2.1	-1.5	1.6	2.0
Noisy workplace	0.8	1.0	1.6	1.0	-0.9	-1.1	-1.2	-1.2	-0.6	-1.1	-1.2	-1.3	0.2	0.4	-1.1
Qualifications: A levels/AS levels or equivalent	0.7	1.5	3.8	0.9	-1.9	-1.2	-1.3	-1.2	-1.6	-1.2	-1.1	-1.1	0.0	-0.9	-1.3
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	2.2	-0.1	-0.7	-0.9	-0.9	-0.9	-1.3	-0.6	-0.9	-0.8	1.1	-1.5	-1.1
Mouth/teeth dental problems: Dentures	0.1	0.2	1.2	0.3	1.1	0.2	0.2	0.2	0.8	0.3	0.2	0.2	0.7	-0.2	0.2
Asthma	0.6	1.2	1.8	-0.3	-1.1	-1.1	-1.3	-1.2	-1.2	-1.2	-1.2	-1.2	0.6	-0.6	-1.3
Medication: Ibuprofen (e.g. Nurofen)	2.4	3.1	5.0	-0.9	-1.2	-1.6	-1.8	-1.7	-2.2	-2.0	-1.7	-1.7	1.7	-2.2	-2.0
Medication: Cholesterol lowering	1.2	1.9	4.8	-2.2	2.1	1.2	1.2	1.2	1.2	1.3	1.2	1.2	0.9	-0.6	1.4
Depression (self-reported)	0.2	0.3	1.7	1.3	0.5	0.4	0.2	0.3	0.7	0.6	0.3	0.2	-0.1	0.0	0.3
Medication: Lansoprazole	2.8	3.2	4.7	0.8	-1.8	-1.9	-2.0	-2.2	-1.3	-2.0	-2.2	-2.2	0.9	-1.5	-2.0
Prospective memory result	1.9	2.4	4.7	0.0	-0.7	-1.5	-1.7	-1.7	-1.4	-0.8	-1.7	-1.7	2.0	-2.2	-1.7
Lung cancer (father)	1.0	1.1	3.1	1.5	-0.5	-0.7	-1.1	-1.0	-0.9	-0.9	-1.1	-1.1	0.3	-1.7	-1.0
Illnesses of mother	0.1	0.2	0.3	0.2	-0.4	-0.4	-0.3	-0.3	-0.5	-0.5	-0.3	-0.2	0.6	0.6	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	2.0	6.3	13.2	2.5	-3.6	-2.9	-2.5	-2.5	-2.7	-2.9	-2.5	-2.5	0.1	-0.0	-2.7
Pulse wave Arterial Stiffness index	1.7	2.0	3.0	1.7	-1.4	-1.4	-1.5	-1.6	-1.2	-0.9	-1.6	-1.6	0.1	-1.4	-1.6
Impedance of arm (left)	0.2	1.2	4.0	-2.0	1.5	1.2	0.9	1.1	0.3	0.8	1.0	1.0	-0.4	0.5	1.2
Arm fat mass (right)	0.9	3.8	10.2	-0.7	-0.4	-1.9	-1.8	-2.0	-1.6	-1.3	-2.1	-2.0	2.8	-3.2	-2.0
Trunk predicted mass	0.7	4.0	9.0	3.0	-2.4	-2.0	-1.9	-2.1	-2.2	-1.3	-2.0	-1.9	0.9	-1.1	-2.4
Standing height	0.4	4.3	12.3	3.5	-3.2	-1.7	-1.6	-1.8	-2.8	-1.2	-1.6	-1.6	-1.1	-0.1	-2.1
Length of working week for main job	0.3	0.3	1.6	1.2	-0.7	-0.2	0.0	0.0	-1.1	-0.1	0.1	0.1	0.4	0.2	-0.0
Exposure to tobacco smoke at home	0.8	0.9	1.9	0.4	-0.7	-1.4	-1.2	-1.1	-0.4	-0.6	-1.1	-1.0	1.0	-0.3	-1.1
Breastfed as a baby	1.3	1.6	2.2	0.9	1.0	1.4	1.3	1.4	1.3	1.4	1.4	1.5	-1.2	0.8	1.2
Tense / ‘highly strung’	0.9	1.6	3.8	-1.4	1.4	1.1	1.4	1.4	0.4	1.9	1.4	1.3	0.5	0.0	1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.7	1.3	-0.4	-0.1	-0.2	-0.1	0.2	0.1	-0.1	-0.1	-1.0	0.3	-0.2
Hair/balding pattern: Pattern 4	0.1	0.3	0.6	-0.6	0.8	0.6	0.5	0.5	0.8	0.6	0.5	0.4	-0.2	0.6	0.4
Birth weight of first child	0.5	0.8	3.3	-0.5	-0.3	-1.1	-0.7	-0.4	-1.5	0.5	-0.4	-0.3	1.8	-1.3	-0.5
Peak expiratory flow (PEF)	1.0	2.3	6.7	2.4	-2.6	-1.2	-1.0	-1.1	-2.1	-1.4	-1.1	-1.1	-1.2	0.0	-1.1
Pulse wave reflection index	1.3	1.6	4.1	1.6	0.7	1.4	1.1	1.0	1.6	1.0	1.0	1.1	-2.0	1.0	0.9
Ever highly irritable/argumentative for 2 days	0.8	0.9	2.5	0.1	-0.4	-0.9	-1.0	-0.9	-1.0	-0.4	-0.8	-0.7	1.6	-1.5	-0.9
Loud music exposure frequency	1.7	1.9	3.3	-0.0	-0.6	-1.5	-1.8	-1.7	-0.8	-1.3	-1.8	-1.8	0.9	-1.4	-1.6
Qualifications: O levels/GCSEs or equivalent	2.2	3.6	5.5	1.4	-1.7	-1.6	-2.0	-2.1	-2.3	-2.0	-2.0	-2.0	0.4	-2.0	-2.3
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	1.1	0.4	0.0	0.9	0.9	0.9	1.0	0.9	0.9	0.8	-0.6	0.3	1.0
Blood clot in the leg (DVT)	0.9	1.1	2.8	0.6	0.5	1.1	1.1	1.1	0.9	0.7	1.2	1.1	-1.1	1.7	1.1
Medication: Paracetamol	3.7	6.1	11.3	-0.7	-1.5	-2.8	-2.5	-2.5	-2.7	-2.1	-2.6	-2.6	2.8	-3.4	-2.4
Headache pain in last month	0.2	0.4	1.4	-0.1	1.2	0.7	0.5	0.5	-0.1	0.9	0.5	0.5	0.4	-0.9	0.5
Medication for cholesterol, blood pressure or diabetes	1.8	3.0	5.3	1.5	-2.3	-1.9	-1.9	-1.8	-2.1	-1.9	-1.9	-1.8	0.0	0.3	-1.9
Glaucoma (self-reported)	2.2	2.6	4.5	-1.7	2.1	1.6	1.7	1.7	1.7	1.8	1.6	1.6	-0.2	-0.1	1.9
Gout (self-reported)	0.1	0.1	0.6	-0.8	0.2	0.1	0.1	0.1	-0.2	0.2	0.2	0.2	0.5	0.8	-0.1
Hypothyroidism/myxoedema (self-reported)	1.2	2.3	5.6	-0.5	2.4	1.5	1.1	1.1	1.9	2.4	1.0	1.1	0.4	-2.0	1.1
Medication: Amlodipine	0.8	1.1	4.6	0.3	-0.7	-0.9	-1.1	-0.9	0.5	-1.5	-0.9	-0.9	-0.8	-2.2	-0.9
Medication: Ventolin 100micrograms inhaler	0.3	0.4	0.9	0.3	-0.8	-0.8	-0.8	-0.6	-0.6	-0.4	-0.6	-0.6	0.1	-0.9	-0.7
Birth weight	0.4	0.9	2.4	1.3	-0.9	-1.0	-0.8	-0.8	-1.5	-0.2	-0.8	-0.8	1.1	-0.0	-0.8
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.7	-0.8	0.3	0.4	0.4	0.2	0.6	-0.1	0.3	0.3	-0.7	0.2	0.1
High blood pressure (siblings)	3.5	5.0	7.2	0.5	-2.4	-2.6	-2.6	-2.6	-2.1	-2.4	-2.5	-2.5	1.0	-1.8	-2.7
Forced vital capacity (FVC), Best measure	2.1	7.8	15.1	2.9	-3.9	-3.2	-2.9	-2.8	-3.0	-3.1	-2.7	-2.8	0.2	-0.2	-3.0
Body fat percentage	1.1	4.2	11.9	-2.3	-0.1	-1.9	-1.7	-1.9	-1.6	-1.4	-1.9	-1.9	2.8	-3.5	-1.7
Leg fat percentage (right)	1.6	5.6	10.9	-1.9	-0.9	-2.6	-2.3	-2.4	-1.9	-1.9	-2.5	-2.5	3.1	-3.3	-2.3
Arm fat-free mass (right)	0.6	3.0	4.2	1.8	-1.8	-1.9	-1.6	-1.8	-2.0	-1.0	-1.8	-1.7	1.3	-1.6	-2.0
Exposure to tobacco smoke outside home	0.3	0.5	1.3	-0.3	1.2	0.8	0.7	0.6	1.0	0.5	0.6	0.6	-0.2	0.2	0.5
Comparative body size at age 10	0.1	0.2	0.7	0.0	-0.3	-0.6	-0.5	-0.3	-0.3	-0.0	-0.4	-0.4	0.9	0.4	-0.1
Number of full brothers	0.4	0.5	0.9	-0.9	0.7	0.9	0.9	0.7	0.1	0.9	0.9	0.9	0.2	0.5	0.6
Worry too long after embarrassment	0.7	1.3	3.3	0.7	0.8	1.1	1.1	1.1	0.6	1.5	1.0	1.1	0.9	1.8	1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.5	2.1	0.5	0.3	0.4	0.5	0.6	0.7	1.4	0.6	0.7	-0.4	-0.4	0.7
Wheeze or whistling in the chest in last year	2.5	4.5	6.9	-0.9	-2.0	-2.6	-2.3	-2.3	-2.6	-1.9	-2.2	-2.2	1.9	-1.8	-2.4
Number of children fathered	0.7	0.7	3.7	-0.0	-0.0	-0.8	-0.9	-0.8	-0.7	-0.3	-0.8	-0.9	0.6	-1.9	-0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	2.3	1.5	-0.7	-0.4	-0.3	-0.4	-1.5	-0.7	-0.4	-0.3	0.0	-0.6	-0.6
Age at first live birth	0.4	0.8	1.6	-1.3	0.3	0.8	1.0	1.0	-0.0	0.8	1.0	1.0	-0.7	0.8	1.0
Pulse wave peak to peak time	1.5	1.7	2.5	-1.6	1.2	1.2	1.4	1.5	1.1	0.8	1.6	1.5	-0.3	1.4	1.5
Health satisfaction	0.5	0.6	1.7	1.3	0.3	0.7	0.7	0.6	0.9	1.1	0.7	0.7	-0.8	0.0	0.7
Shortness of breath walking on level ground	0.2	0.2	1.2	-0.8	0.2	-0.2	0.0	-0.0	-0.2	0.1	-0.0	-0.0	1.1	-1.0	-0.1
Qualifications: College or University degree	0.1	0.4	1.6	1.0	-0.8	0.2	0.2	0.3	-0.9	-0.1	0.4	0.4	-0.6	1.2	0.1
Eye problems/disorders: None of the above	3.3	3.8	5.3	0.1	-1.6	-2.2	-2.3	-2.2	-1.8	-1.7	-2.3	-2.3	1.8	-2.0	-2.1
Mouth/teeth dental problems: Loose teeth	0.8	1.0	2.0	-1.4	0.1	-0.8	-0.9	-0.8	-1.3	-1.1	-0.9	-0.9	1.1	-1.3	-0.8
Emphysema/chronic bronchitis	2.3	2.6	4.4	0.2	-1.1	-2.0	-1.9	-1.7	-1.5	-1.2	-1.6	-1.7	1.8	-2.1	-1.8
Medication for pain relief, constipation, heartburn	2.7	4.6	14.0	1.9	1.0	2.1	2.0	2.0	2.1	1.5	2.0	1.9	-2.5	3.7	1.9
Neck or shoulder pain in last month	0.3	0.5	2.5	-1.1	0.2	-0.5	-0.5	-0.4	0.0	0.0	-0.4	-0.5	1.0	-1.6	-0.2
Medication: Blood pressure	0.4	0.7	2.3	-1.5	1.1	0.7	0.7	0.6	0.9	0.6	0.7	0.6	0.4	-0.9	0.5
Angina (self-reported)	0.2	0.3	0.7	-0.7	-0.5	-0.6	-0.3	-0.3	-0.3	-0.3	-0.2	-0.3	0.8	-0.8	-0.3
Migraine (self-reported)	0.1	0.2	0.7	0.9	-0.1	-0.4	-0.3	-0.3	-0.5	-0.5	-0.2	-0.3	-0.1	0.0	-0.4
Medication: Ibuprofen	1.8	2.2	4.4	-1.3	-0.6	-1.1	-1.4	-1.4	-1.8	-1.9	-1.4	-1.4	1.3	-2.1	-1.6
Medication: Allopurinol	0.1	0.2	0.7	-0.6	-0.1	0.2	0.4	0.3	0.2	0.3	0.3	0.3	0.0	0.9	0.3
Medication: Omeprazole	0.6	0.7	3.5	-1.7	0.6	0.1	0.3	0.4	-0.7	0.8	0.5	0.4	1.9	0.3	0.5
Medication: Seretide 50 evohaler	0.8	0.9	1.9	-0.1	0.8	1.0	1.0	1.0	1.1	0.8	1.1	1.1	-1.4	0.2	0.9
Mean time to correctly identify matches	0.9	1.7	2.7	-0.6	1.5	1.5	1.3	1.4	1.6	1.1	1.3	1.4	-0.4	1.6	1.3
Heart disease (mother)	0.7	0.8	4.7	2.2	-1.0	-0.0	0.1	-0.0	0.2	-0.4	-0.2	-0.2	-1.2	1.4	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	3.5	0.3	0.3	0.9	1.0	0.7	-0.3	0.6	0.8	0.8	-0.6	1.9	0.7
Whole body fat mass	1.0	4.0	10.3	-1.0	-0.7	-2.0	-1.9	-2.1	-1.8	-1.5	-2.1	-2.1	2.5	-3.2	-2.0
Leg fat mass (right)	0.9	3.6	7.2	-0.9	-0.7	-2.0	-1.8	-2.0	-1.7	-1.4	-2.0	-1.9	2.6	-2.7	-2.0
Arm predicted mass (right)	0.6	3.0	4.6	2.1	-1.8	-1.9	-1.6	-1.8	-1.9	-1.0	-1.8	-1.8	1.4	-1.4	-2.0
Pulse rate, automated reading	1.0	3.1	12.2	-3.0	0.8	-1.4	-1.1	-1.0	-1.4	-0.5	-1.1	-1.1	3.5	-2.5	-0.9
Alcohol intake frequency.	0.6	1.3	4.3	-2.1	1.6	0.8	0.9	0.9	0.3	1.0	0.9	0.9	1.1	-1.3	0.8
Comparative height size at age 10	0.1	0.5	1.2	0.7	-1.0	-0.5	-0.6	-0.7	-1.1	-0.4	-0.5	-0.5	-0.5	0.3	-0.9
Number of full sisters	1.1	1.3	3.5	-1.8	-0.2	-1.2	-1.1	-0.9	-0.8	-0.4	-0.9	-0.8	1.6	-1.9	-0.8
Suffer from ‘nerves’	0.7	1.0	2.1	-0.8	1.4	1.0	1.0	1.1	0.3	1.4	1.0	1.0	0.8	-0.3	1.3
Overall health rating	0.1	0.3	1.3	0.1	0.2	0.3	0.4	0.4	0.5	1.1	0.4	0.4	0.6	-0.4	0.5
Chest pain or discomfort	0.3	0.4	2.0	-0.0	-0.9	-0.8	-0.1	0.0	-0.9	0.7	0.1	0.1	1.4	0.0	0.0
Had major operations	0.4	0.5	3.1	0.3	0.3	-0.0	-0.5	-0.6	-0.4	-0.5	-0.5	-0.5	0.2	-1.8	-0.7
Age at last live birth	0.4	0.5	2.6	-1.6	0.4	0.6	0.7	0.7	-0.3	0.7	0.7	0.7	-0.3	-0.1	0.8
Family relationship satisfaction	0.5	0.7	1.2	-0.7	0.9	0.8	0.8	0.9	0.3	1.1	0.9	1.0	0.6	-0.7	0.9
Leg pain on walking	0.7	0.9	1.7	1.3	-1.2	-0.8	-0.9	-1.0	-1.1	-0.7	-0.8	-0.8	0.1	-0.9	-1.1
Qualifications: NVQ or HND or HNC or equivalent	3.4	4.1	6.0	-0.5	-1.6	-2.2	-2.3	-2.4	-2.3	-2.0	-2.4	-2.4	1.8	-0.7	-2.4
Commuting to job workplace: Car/motor vehicle	1.4	1.6	3.3	-0.8	-1.8	-1.6	-1.3	-1.2	-1.2	-1.7	-1.2	-1.2	-0.1	-0.9	-1.2
Illness, injury, bereavement, stress in last 2 years	4.0	4.9	6.7	0.1	1.2	2.4	2.6	2.5	2.3	2.0	2.5	2.5	-2.4	2.1	2.5
Medication: Aspirin	0.5	0.7	6.1	-0.3	-0.5	-0.6	-0.5	-0.5	-0.1	0.0	-0.4	-0.4	0.5	-2.5	-0.5
Supplements: Vitamin C	0.8	0.9	1.8	1.4	-0.8	-0.9	-1.2	-1.1	-0.8	-0.9	-1.0	-1.1	0.4	-0.2	-1.2
Knee pain experienced in last month	0.6	0.9	1.4	0.4	-1.0	-1.0	-1.0	-1.2	-0.3	-1.2	-1.2	-1.1	-0.0	-0.7	-1.1
Hypertension (Self-reported)	0.3	0.8	4.3	-0.7	0.2	-0.8	-0.7	-0.7	0.3	-0.2	-0.7	-0.7	1.1	-2.1	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	2.5	-1.6	0.5	0.4	0.5	0.6	0.5	0.9	0.5	0.5	0.8	-0.6	0.7
Illnesses of father: Heart disease	0.1	0.1	0.6	-0.7	-0.4	-0.4	0.0	0.1	0.2	0.4	0.1	0.1	0.7	0.3	0.1
Illnesses of siblings: Diabetes	0.3	0.4	2.5	-1.6	0.4	0.1	0.3	0.4	-0.3	0.5	0.6	0.5	0.4	0.7	0.4
Smoking status: Previous	0.2	0.3	1.4	0.4	-0.4	-0.5	-0.5	-0.3	-0.8	0.2	-0.3	-0.2	1.2	-0.7	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	2.2	4.6	11.1	1.8	-2.9	-2.6	-2.1	-1.9	-3.3	-1.6	-1.9	-2.0	1.4	-0.6	-2.0
Whole body fat-free mass	0.5	2.6	7.0	2.6	-1.8	-1.6	-1.4	-1.6	-1.8	-0.9	-1.5	-1.5	0.9	-1.2	-1.8
Leg fat-free mass (right)	0.2	1.3	6.2	2.5	-1.1	-1.0	-0.9	-0.9	-1.1	-0.3	-0.9	-0.9	0.4	-1.0	-1.1
Arm fat percentage (left)	0.8	3.2	10.4	-1.9	0.5	-1.4	-1.4	-1.5	-1.1	-1.0	-1.6	-1.6	3.0	-3.2	-1.4
Average weekly red wine intake	1.8	2.7	6.2	1.4	-2.5	-1.7	-1.7	-1.8	-1.9	-1.0	-1.8	-1.8	0.3	-1.2	-1.7
Handedness (chirality/laterality): Left-handed	0.9	1.0	4.1	1.6	-2.0	-0.8	-0.5	-0.4	-0.2	-0.9	-0.3	-0.4	-1.6	0.7	-0.7
Mood swings	0.6	1.1	3.7	-1.5	1.9	0.6	0.5	0.6	0.6	1.3	0.6	0.6	1.7	0.6	0.8
Loneliness, isolation	1.3	1.8	6.0	-0.0	-1.0	-1.5	-1.3	-1.2	-1.8	-0.6	-1.3	-1.3	2.4	-1.0	-1.1
Long-standing illness, disability or infirmity	0.5	0.7	3.2	-1.5	0.8	-0.2	-0.4	-0.3	-0.2	0.3	-0.3	-0.3	1.8	-1.2	-0.2
Ever had bowel cancer screening	1.5	1.8	5.3	0.6	-1.5	-1.4	-1.5	-1.3	0.1	-1.2	-1.3	-1.2	-1.2	-2.3	-1.2
Diabetes diagnosed by doctor	1.4	2.2	8.6	-2.9	0.1	-1.2	-0.9	-0.9	-1.4	-0.7	-0.9	-0.9	2.9	-1.3	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	2.6	0.1	-0.7	-1.2	-1.3	-1.3	-1.1	-0.2	-1.3	-1.2	0.9	-1.6	-1.3
Friendships satisfaction	0.9	1.1	1.8	0.0	1.1	1.3	1.1	1.2	1.3	0.9	1.2	1.2	-0.2	0.2	1.3
Qualifications: nursing, teaching	1.9	3.0	4.3	-0.5	1.1	2.0	1.9	2.1	1.7	1.7	2.1	2.1	-1.7	0.9	2.0
Commuting to job workplace: Walk	0.3	0.3	1.9	1.4	-0.0	0.5	0.3	0.2	0.4	0.6	0.2	0.2	-0.0	1.1	0.2
Eye problems/disorders: Cataract	0.4	0.5	0.9	0.2	0.5	0.8	0.8	0.7	0.5	1.0	0.8	0.8	-0.5	0.9	0.7
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.8	-0.2	-0.0	0.1	0.2	0.1	0.8	0.0	0.0	0.1	-0.6	-0.9	0.3
Medication for cholesterol	0.3	0.4	2.6	1.6	-0.7	0.1	0.0	0.0	-0.4	-0.3	0.1	0.1	-0.1	1.4	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.4	-0.0	0.0	-0.3	-0.5	-0.4	0.1	0.2	-0.2	-0.2	0.2	-0.3	-0.6
Back pain experienced in last month	0.4	0.6	0.9	0.8	-0.8	-0.7	-0.9	-0.9	0.2	-0.8	-1.0	-1.0	-0.1	-0.7	-0.8
Mineral and other dietary supplements	2.0	2.7	5.9	0.6	1.7	1.6	1.6	1.7	2.4	2.1	1.7	1.6	-1.4	-0.0	1.8
Breast cancer (self-reported)	0.3	0.4	3.1	0.7	-0.2	-0.2	-0.1	-0.1	-0.2	0.7	0.0	0.0	-0.1	-1.8	-0.2
Asthma (self-reported)	0.6	1.1	1.7	-0.5	-0.9	-1.0	-1.2	-1.2	-1.3	-1.1	-1.1	-1.1	0.7	-0.8	-1.3
Osteoporosis (self-reported)	0.8	1.0	4.3	1.3	-0.4	0.8	1.0	1.0	0.1	0.9	0.9	0.9	-0.5	2.1	1.0
Osteoarthritis (self-reported)	1.1	1.5	2.9	-0.0	-0.9	-1.5	-1.5	-1.4	-0.7	-1.7	-1.5	-1.5	0.8	-0.4	-1.3
Medication: Aspirin	0.7	0.9	7.5	-0.6	-0.4	-0.7	-0.6	-0.6	-0.4	-0.2	-0.6	-0.6	0.8	-2.7	-0.7
Medication: Gliclazide	0.6	0.7	3.3	-1.1	-0.3	-0.7	-0.5	-0.4	-0.7	-0.5	-0.3	-0.4	1.8	-0.9	-0.6
Illnesses of father: None of the above (group 1)	0.2	0.3	2.9	1.7	0.0	0.4	-0.1	-0.1	0.1	-0.1	-0.2	-0.2	-0.5	0.3	-0.0
Smoking status: Current	0.1	0.2	0.7	-0.8	0.8	0.2	0.1	0.1	-0.2	0.6	0.1	0.1	0.8	-0.5	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.6	3.3	10.2	1.8	-3.2	-2.3	-1.7	-1.8	-1.5	-1.8	-1.8	-1.8	-0.1	0.5	-1.7
Whole body water mass	0.5	2.6	7.5	2.7	-1.8	-1.6	-1.4	-1.6	-1.8	-0.8	-1.5	-1.5	0.9	-1.1	-1.8
Leg predicted mass (right)	0.2	1.2	6.1	2.5	-1.0	-1.0	-0.9	-0.9	-1.0	-0.3	-0.9	-0.9	0.5	-1.0	-1.1
Arm fat mass (left)	1.0	4.1	11.1	-0.9	-0.3	-1.9	-1.8	-2.0	-1.7	-1.3	-2.1	-2.0	3.0	-3.3	-2.0
Number of self-reported non-cancer illnesses	0.8	1.4	3.8	0.0	-0.2	-1.3	-1.5	-1.3	-0.7	-0.3	-1.2	-1.3	1.5	-1.9	-1.2
Average weekly champagne plus white wine intake	0.5	0.7	4.5	1.4	-0.8	0.3	-0.0	-0.1	1.0	-0.7	-0.1	-0.1	-2.1	-0.7	0.1
Miserableness	0.8	1.4	2.3	0.8	-0.8	-1.2	-1.5	-1.5	-0.8	-0.8	-1.4	-1.5	1.0	-1.1	-1.5
Guilty feelings	1.1	1.7	4.3	-0.9	1.2	1.0	1.3	1.3	0.6	2.1	1.2	1.2	1.3	1.7	1.3
Wears glasses or contact lenses	0.7	0.8	2.3	1.0	0.2	1.1	0.9	0.8	-0.0	0.8	0.8	0.8	-1.5	0.9	0.8
Ever taken oral contraceptive pill	1.3	1.4	2.4	-0.9	-0.9	-1.3	-1.0	-1.2	-1.4	-0.9	-1.2	-1.2	1.5	-1.6	-1.2
Hearing aid user	2.0	2.3	3.3	-0.8	1.8	1.8	1.6	1.6	1.8	1.6	1.6	1.6	-1.0	-0.4	1.8
Mother’s age at death	0.1	0.1	0.5	0.7	-0.6	-0.4	-0.2	-0.3	0.2	-0.5	-0.2	-0.2	-0.2	-0.0	-0.1
Financial situation satisfaction	1.2	1.4	9.1	3.0	-0.8	-0.4	-1.0	-1.0	-0.3	-1.1	-0.9	-0.9	-0.9	-0.5	-1.1
Tinnitus: Yes, now most or all of the time	0.2	0.2	1.0	1.0	-0.3	0.0	-0.1	-0.0	0.4	-0.4	-0.1	-0.1	-0.8	0.7	0.2
Commuting to job workplace: Public transport	0.3	0.3	1.6	0.6	0.7	0.7	0.1	0.2	1.3	0.0	0.3	0.3	-0.8	-0.3	0.0
Eye problems/disorders: Glaucoma	3.2	3.8	6.1	-1.1	2.5	2.2	2.3	2.3	2.0	1.8	2.2	2.2	-0.9	0.8	2.2
Medication: Blood pressure	0.3	0.5	2.6	-1.4	0.6	-0.5	-0.3	-0.2	0.5	0.0	-0.3	-0.3	0.6	-1.6	-0.0
Pain type(s) experienced in last month: Hip pain	0.9	1.2	2.9	1.7	-1.1	-0.9	-1.0	-1.2	-0.4	-1.3	-1.2	-1.2	-0.2	0.4	-1.2
Supplements: Fish oil (including cod liver oil)	1.2	1.6	3.5	-1.0	-0.6	-1.1	-1.2	-1.2	-1.9	-1.5	-1.1	-1.1	1.8	-0.4	-1.3
High cholesterol (Self-reported)	0.9	1.6	4.4	-2.1	2.0	0.9	0.9	1.0	0.3	1.4	1.0	1.0	1.2	-1.6	0.9
Medication: Bendroflumethiazide	0.2	0.3	1.0	0.8	-0.1	-0.5	-0.5	-0.6	-0.1	-0.5	-0.7	-0.7	1.0	-0.1	-0.6
Medication: Paracetamol	2.6	4.0	7.1	-0.4	-1.2	-2.2	-2.0	-1.9	-2.6	-1.7	-2.0	-2.0	2.3	-2.7	-1.8
Medication: Lisinopril	0.4	0.5	1.8	-0.5	0.2	-0.5	-0.7	-0.8	0.3	-0.4	-0.8	-0.8	0.3	-1.3	-0.7
Medication: Atorvastatin	2.9	3.6	6.9	1.0	-2.6	-2.2	-2.0	-2.1	-2.2	-1.4	-2.0	-2.1	1.6	-0.4	-2.0
Illnesses of father: High blood pressure	1.9	2.3	7.8	-1.0	-1.2	-1.9	-1.2	-1.1	-1.9	-1.0	-1.1	-1.2	2.8	-1.7	-1.2
Alcohol drinker status: Never	1.4	1.7	2.9	-1.0	1.3	1.2	1.4	1.6	1.2	1.2	1.7	1.7	-0.5	0.3	1.5
Ever smoked	1.3	2.3	7.7	-0.9	-0.6	-1.4	-1.4	-1.2	-1.9	-0.5	-1.1	-1.1	2.3	-2.8	-1.3
Basal metabolic rate	0.6	3.2	4.8	2.2	-1.8	-1.9	-1.7	-1.9	-2.0	-1.1	-1.8	-1.8	1.2	-1.6	-2.1
Leg fat percentage (left)	1.5	5.4	11.0	-1.6	-1.0	-2.6	-2.3	-2.4	-1.9	-1.9	-2.5	-2.4	2.8	-3.3	-2.3
Arm fat-free mass (left)	0.9	4.4	6.0	1.9	-2.2	-2.3	-2.0	-2.2	-2.4	-1.4	-2.2	-2.2	1.5	-1.9	-2.4
Number of operations (self-reported)	0.3	0.4	1.5	0.7	0.8	0.6	0.2	0.4	1.2	0.4	0.4	0.5	-0.7	-1.0	0.3
Average weekly beer plus cider intake	0.4	0.6	2.0	0.8	-1.4	-0.9	-0.7	-0.7	-0.6	-0.9	-0.7	-0.7	-0.4	0.4	-0.7
Irritability	0.7	1.1	2.6	0.3	0.8	1.1	1.2	1.2	1.0	1.6	1.2	1.1	0.2	0.6	1.4
Risk taking	1.1	1.7	6.3	-0.9	-0.6	-1.4	-1.1	-0.9	-1.4	-0.5	-0.9	-0.9	2.5	-1.9	-1.0
Ever had prostate specific antigen (PSA) test	1.1	1.2	2.0	0.0	-1.0	-1.2	-1.3	-1.3	-0.7	-1.3	-1.4	-1.4	0.1	-1.2	-1.2
Fractured/broken bones in last 5 years	1.1	1.4	3.7	-1.3	1.2	1.0	1.2	1.3	0.2	1.9	1.3	1.4	0.5	0.3	1.2
Age started oral contraceptive pill	2.4	3.0	4.4	-0.5	-2.0	-2.1	-1.7	-1.8	-1.8	-1.8	-1.8	-1.7	1.2	-2.0	-1.9
Diastolic blood pressure, automated reading	1.2	3.7	6.6	-2.3	-0.9	-2.2	-1.9	-1.8	-1.3	-1.9	-2.0	-2.0	2.6	-2.1	-1.6
Ever depressed for a whole week	0.6	0.8	5.6	0.4	0.2	-0.5	-0.9	-0.6	0.4	0.1	-0.6	-0.6	0.9	-2.4	-0.6
Unable to work because of sickness or disability	1.6	2.1	5.9	-0.5	1.8	1.3	1.4	1.4	2.4	1.9	1.4	1.4	-0.5	0.2	1.6
Commuting to job workplace: Cycle	0.1	0.1	0.3	-0.5	-0.0	0.2	0.3	0.0	-0.2	0.2	0.1	0.1	0.2	-0.5	0.0
Myopia	0.1	0.1	0.3	-0.4	0.1	0.5	0.4	0.3	-0.1	0.6	0.2	0.2	0.0	-0.1	0.5
Vascular/heart problems diagnosed by doctor	0.2	0.7	4.6	1.0	-0.6	0.4	0.4	0.4	-0.9	0.0	0.4	0.4	-0.7	2.1	0.3
Cholesterol lowering medication	0.6	0.9	3.2	-1.8	1.4	0.4	0.4	0.4	0.7	1.1	0.4	0.4	1.2	-1.2	0.5
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	4.2	-1.0	-0.2	-0.7	-0.5	-0.3	-1.1	0.4	-0.2	-0.2	2.0	-0.3	-0.2
Pain experienced in last month	0.2	0.3	0.9	-0.8	0.4	0.1	0.1	0.1	-0.9	0.1	0.1	0.1	0.9	0.8	0.0
Supplements: Calcium	0.4	0.4	1.0	0.6	-0.5	-0.4	-0.6	-0.6	-1.0	-0.3	-0.5	-0.5	0.9	-0.6	-0.8
Basal cell carcinoma (self-reported)	1.2	1.4	2.6	-0.8	1.6	1.3	1.2	1.3	1.2	1.5	1.1	1.1	-0.1	0.6	1.5
Heart attack/myocardial infarction (self-reported)	0.1	0.2	0.9	-0.0	-0.5	-0.2	0.1	0.2	-0.3	0.6	0.2	0.3	1.0	0.2	0.3
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	2.6	0.8	0.4	1.0	1.0	1.0	0.8	0.6	1.1	1.0	-1.1	1.6	0.9
Heart disease (siblings)	0.4	0.5	1.5	0.9	0.8	0.6	0.4	0.4	1.2	0.9	0.4	0.4	-0.2	-0.8	0.5
Alcohol drinker status: Previous	0.8	0.9	2.7	-0.8	1.0	1.0	0.9	0.9	-0.0	0.8	0.8	0.9	1.1	1.7	0.8
Pack years of smoking	1.9	2.8	4.8	-0.7	2.2	1.9	1.8	1.7	2.1	2.1	1.7	1.6	-0.3	0.5	1.9
Impedance of whole body	0.1	0.5	5.1	-2.3	0.4	0.1	-0.0	0.1	-0.9	-0.1	0.1	0.0	0.1	-0.2	0.2
Leg fat mass (left)	1.1	4.1	8.8	-0.8	-0.9	-2.2	-2.0	-2.1	-1.9	-1.6	-2.1	-2.1	2.6	-3.0	-2.1
Arm predicted mass (left)	0.9	4.5	5.9	2.2	-2.3	-2.3	-2.1	-2.2	-2.4	-1.4	-2.2	-2.2	1.5	-1.9	-2.4