Hub : Genes

ZNF778

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0700	0.0340	2.3e-02	0.027	-0.001	0.010	0.005	0.024	2.4e-04	0.48000	1.7e-02	7.7e-02	6.0e-04
2	GTEx	Brain Cerebellar Hemisphere	0.4690	0.1070	1.6e-06	0.062	NA	0.140	NA	0.152	1.1e-02	NA	1.9e-04	NA	1.0e-04
3	GTEx	Liver	0.6210	0.1040	6.4e-06	0.251	NA	0.178	NA	0.204	1.2e-07	NA	1.1e-05	NA	2.3e-06
4	GTEx	Pancreas	0.4910	0.0650	4.4e-13	0.107	NA	0.351	NA	0.329	3.0e-05	NA	1.3e-15	NA	1.6e-14
5	GTEx	Testis	0.1450	0.0670	5.9e-03	0.013	NA	0.075	NA	0.058	8.1e-02	NA	3.1e-04	NA	1.5e-03
6	METSIM	Adipose	0.1222	0.0404	6.8e-04	0.046	0.020	0.047	0.028	0.036	1.5e-07	0.00051	1.1e-07	4.4e-05	3.9e-06
7	TCGA	Colon Adenocarcinoma	0.0800	0.0490	2.9e-03	0.051	0.042	0.030	NA	0.044	6.3e-04	0.00170	7.6e-03	NA	1.4e-03
8	TCGA	Prostate Adenocarcinoma	0.0986	0.0424	9.0e-05	0.017	0.025	0.023	NA	0.022	6.2e-03	0.00110	1.8e-03	NA	2.3e-03
9	TCGA	Thyroid Carcinoma	0.0510	0.0260	3.6e-03	0.017	0.025	0.018	NA	0.013	7.1e-03	0.00160	6.4e-03	NA	1.8e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.7	1.0	2.9	-1.3	-0.1	0.5	1.7	0.7	1.7	0.6	-0.3	0.9
Bipolar Disorder or Schizophrenia	1.0	2.5	8.0	-1.1	1.1	-1.7	-0.4	1.5	2.8	-1.3	-2.1	-1.0
Depressed Affect (Nagel 2018)	0.5	1.0	2.2	-0.6	0.6	-0.7	-1.5	-1.2	1.1	-1.1	-1.1	-0.3
Depression (Nagel 2018)	0.9	1.4	5.3	-0.2	-0.4	-0.2	-1.6	-2.3	-0.1	-1.5	-1.3	-0.6
Intelligence (Savage-Jansen 2018)	0.3	1.0	4.2	1.4	-0.7	-0.5	-0.9	-0.3	-2.1	-0.7	0.2	-0.8
Neuroticism (Nagel 2018)	0.4	0.8	2.9	-0.9	0.4	-0.4	-1.7	-0.5	-0.1	-1.2	-1.1	-0.8
Schizophrenia (2018)	1.7	3.4	6.5	-0.3	1.4	-2.5	-1.5	1.3	2.1	-2.1	-2.4	-1.9
Schizophrenia vs Biploar Disorder	1.5	2.0	4.8	0.3	0.1	-1.9	-1.5	0.0	0.0	-2.1	-2.2	-1.9
Worry (Nagel 2018)	0.2	0.4	0.8	-0.6	0.3	0.8	-0.9	0.6	-0.9	-0.2	-0.5	-0.5
Alzheimer’s Disease (in mother)	0.6	0.7	1.8	-0.8	-0.4	1.1	1.0	1.4	0.6	0.6	0.6	0.9
Alzheimer’s Disease (in father)	0.3	0.3	1.2	-0.3	-1.1	-0.4	-0.4	-0.3	-0.3	0.1	-0.5	-0.7
Alzheimer’s Disease (including proxy)	0.3	0.4	1.5	-1.0	-0.9	0.3	0.2	1.2	0.3	0.0	-0.4	0.5
Crohns Disease (2017)	0.2	0.5	1.8	0.2	1.3	0.1	1.1	0.5	0.2	0.6	1.0	0.2
Irritable Bowel Disease (IBD)	0.3	0.6	2.7	1.6	0.9	-0.8	-0.4	-0.5	-0.3	-0.3	0.5	-0.9
Ulcerative Colitis (UC)	0.7	1.3	4.3	2.1	0.5	-0.7	-1.5	-1.0	-0.5	-0.6	-0.3	-1.7
Major Depression (MDD)	0.2	0.2	1.1	0.0	0.0	0.0	0.0	0.0	0.0	-1.1	-1.0	0.3
Reaction Time	0.3	0.7	1.9	-1.4	-0.3	0.8	-0.2	-0.5	-0.4	1.2	-1.0	-0.7
Verbal and Numeric Reasoning (VNR)	1.6	3.8	14.2	3.8	0.3	-0.9	-2.0	-2.1	-2.4	-0.6	0.1	-2.2
Breast Cancer	0.2	0.4	0.7	-0.5	-0.5	0.6	-0.6	0.2	0.8	0.7	-0.8	-0.6
Ovarian Cancer	0.7	0.9	3.8	0.4	-2.0	-0.1	-1.4	-0.7	0.8	0.2	-0.9	-0.6
Prostate Cancer	0.4	0.6	2.7	-1.6	0.4	-0.4	-0.0	1.1	0.6	0.1	0.1	0.8
Age at First Birth	2.8	4.1	10.8	2.7	-0.8	-0.4	-3.3	-2.5	-0.7	-1.1	-1.0	-3.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.8	1.0	5.7	-0.1	0.6	-0.9	0.6	2.4	-1.3	-0.5	0.0	0.4
Coronary Artery Disease (CAD)	0.1	0.1	0.3	0.3	-0.0	-0.5	-0.3	0.0	0.0	-0.5	-0.1	-0.5
Crohns Disease (2012)	1.0	1.6	3.9	-1.1	1.8	1.3	0.5	-1.7	-0.6	2.0	1.0	-0.7
Mean Putamen Volume	0.4	0.5	1.8	1.0	-0.0	-0.5	-0.4	-0.3	-0.2	-1.4	-1.0	-0.2
Fasting Glucose	1.0	1.2	4.8	0.0	0.0	-2.2	-1.2	0.1	-0.4	-1.2	-1.1	-1.3
HbA1C	1.1	1.2	4.9	-1.3	2.2	-0.8	-0.4	0.5	-0.8	-0.9	0.1	1.3
HDL Cholesterol	1.7	2.8	10.9	2.0	-3.3	-0.6	-1.9	-1.6	-1.0	-0.7	-0.6	-1.4
LDL Cholesterol	0.4	0.6	4.0	-2.0	-0.0	-0.3	0.3	0.5	-0.0	-0.7	-0.0	0.4
Lupus	0.6	0.8	1.7	-0.8	1.0	0.3	1.2	1.3	-0.9	1.1	0.7	0.4
Neuroticism (2016)	0.5	0.8	2.6	0.2	-0.4	-0.3	-0.9	-1.0	-1.6	-0.8	-0.3	-1.2
Primary Biliary Cirrhosis	1.2	1.6	4.9	-0.1	0.6	0.1	1.8	1.8	-0.6	0.0	1.6	2.2
Rheumatoid Arthritis	0.2	0.3	0.6	-0.5	-0.8	-0.5	0.6	-0.1	0.4	0.7	0.1	-0.4
Schizophrenia (2014)	1.4	3.1	7.7	-1.7	2.4	-1.8	0.8	2.8	2.8	-0.7	-0.5	0.3
Triglycerides	1.1	1.8	6.2	-1.7	1.1	-0.8	1.5	2.5	1.0	-0.7	0.4	1.3
Type 2 Diabetes (T2D) (2012)	1.0	1.1	4.6	-1.2	0.2	1.1	1.2	-0.1	-1.2	2.1	0.5	-0.0
Ulcerative Colitis	0.5	0.7	2.5	0.6	0.9	0.7	-0.1	-1.6	0.0	0.7	1.1	-0.7
Blood Eosinophil Count	0.6	4.2	13.4	2.5	-2.0	-1.8	-1.9	-3.7	0.4	-1.2	-0.9	-2.3
Blood Platelet Count	0.3	3.5	8.5	1.9	-0.1	-1.4	-2.0	-2.9	2.6	-2.3	-0.8	-0.8
Blood Red Count	0.4	3.5	23.0	-0.4	-4.8	0.0	1.3	-0.6	-2.1	-1.1	-0.3	-0.5
Blood White Count	0.3	2.4	7.0	2.6	1.7	0.4	1.8	-0.8	1.5	-0.2	2.0	1.4
Heel T-Score	0.6	4.4	10.2	2.7	-2.9	-2.0	1.2	0.3	-3.2	-2.4	0.7	1.3
BMI	0.5	2.9	12.0	-2.6	0.9	-0.9	1.3	3.5	-0.7	-0.2	0.6	1.7
Height	0.6	12.3	35.9	5.6	0.1	1.2	4.8	-2.2	0.1	1.8	6.0	3.3
Waist Hip Ratio (WHR)	0.1	0.4	1.8	0.5	0.5	0.3	0.3	0.6	1.3	-0.3	-0.4	0.4
Systolic Blood Pressure	1.3	6.4	16.1	-3.4	4.0	2.3	1.4	4.0	-2.2	1.2	-0.7	0.4
Smoking Status	1.4	3.4	9.4	0.8	0.1	-3.1	-1.4	0.1	1.8	-2.5	-2.6	-1.7
Allergy or Eczema	0.5	1.4	5.2	-2.3	1.2	-0.5	0.2	0.8	1.1	-1.1	0.4	1.6
Cardiovascular Disease	0.5	1.8	5.2	-2.1	1.7	0.7	-0.9	0.1	-2.3	0.2	-1.5	-0.4
Hypothyroidism (self reported)	0.7	1.7	5.6	-1.3	-1.9	0.2	1.0	1.2	2.4	0.4	0.5	1.1
Respiratory disease	0.7	1.6	3.6	-0.5	0.3	-1.0	-1.2	-1.2	1.2	-1.9	-1.9	-1.2
Type 2 Diabetes (T2D) (2018)	0.6	1.2	4.7	-1.4	-0.1	-0.8	-0.0	2.2	0.2	-0.7	-1.7	0.1
Lung FEV1/FVC ratio	0.7	3.3	6.4	0.1	-0.7	2.2	1.8	2.3	-1.2	2.2	1.8	2.5
Lung FVC	0.6	3.0	7.3	2.7	0.8	2.4	1.0	-1.5	-0.2	2.4	2.1	-0.1
Neuroticism	0.6	1.6	4.0	-1.4	0.9	-0.3	-2.0	-0.4	0.3	-0.9	-1.8	-1.7
Chronotype (morning person)	0.3	0.8	1.6	0.9	0.6	0.1	-0.2	-1.3	-1.2	1.2	0.9	-0.7
Hair Pigment	23.7	675.8	2332.9	17.4	10.3	-18.4	-38.0	-17.4	-48.3	-13.0	-12.0	-30.7
Tanning	34.4	419.7	1600.0	-23.1	-2.1	10.8	27.3	12.3	40.0	7.3	5.0	23.4
Hand grip strength (left)	0.2	0.5	1.8	1.1	-0.4	0.3	0.4	-0.1	-1.3	-0.7	0.3	0.5
Number of treatments/medications taken	1.8	3.2	9.8	-0.3	0.8	-1.8	-2.7	-1.8	-0.2	-0.6	-2.1	-3.1
Average weekly spirits intake	0.3	0.4	1.3	0.4	-0.2	0.8	0.6	-0.0	1.0	0.5	1.1	0.4
Sensitivity / hurt feelings	0.9	1.5	3.2	-1.8	-0.4	-0.6	-1.2	1.3	1.0	-0.9	-1.2	-1.8
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.0	-0.8	0.1	0.2	-1.4	-1.2	0.2	-1.0	-0.9	-0.4
Hearing difficulty/problems: Yes	1.7	2.6	7.4	-0.8	0.3	-0.9	-1.7	-1.3	2.0	-0.7	-2.4	-2.7
Relative age of first facial hair	1.2	2.4	5.7	2.1	-0.3	-1.8	-1.7	-0.5	-2.4	-1.0	-1.1	-1.6
Other serious medical condition/disability diagnosed by doctor	2.0	2.6	8.8	1.3	-0.0	-0.9	-2.3	-1.5	1.4	-0.4	-1.5	-3.0
Ever used hormone-replacement therapy (HRT)	0.7	0.9	2.0	1.4	-1.4	-1.1	-0.7	-0.3	0.2	-0.7	-1.1	-1.0
Ever had hysterectomy (womb removed)	1.1	1.3	3.1	-1.8	0.7	1.0	0.6	-1.5	1.2	1.6	0.5	-0.2
Systolic blood pressure, automated reading	1.0	2.8	6.0	-1.7	2.5	1.4	1.5	2.3	-2.0	1.1	-0.3	0.9
Eye problems/disorders: Diabetes related eye disease	1.4	1.5	2.8	-0.2	-0.3	1.7	1.5	1.3	0.5	1.7	1.6	1.0
Angina	0.9	1.2	3.1	-0.7	-0.1	-1.2	-0.8	1.7	1.0	-0.9	-1.8	-0.6
Medication for hormone replacement therapy	1.2	1.3	2.7	-1.6	-1.5	0.3	1.2	1.2	-1.3	-0.4	-0.4	1.4
Vitamin and mineral supplements	1.0	1.4	3.5	1.4	-0.8	0.0	-1.9	-1.7	0.2	-0.6	-1.6	-0.9
Supplements: Zinc	5.0	5.4	11.5	-3.4	2.6	2.9	2.8	2.5	0.3	2.1	1.4	1.0
Medication: Co-codamol	0.2	0.3	0.9	-0.3	0.3	0.1	-0.4	-0.9	-0.3	0.3	-0.4	-0.9
Medication: Metformin	0.7	1.0	3.2	-0.5	-1.1	-0.8	0.6	1.8	-0.7	-1.0	-0.8	0.9
Diabetes (father)	0.6	0.8	3.6	0.5	1.9	-0.2	-0.6	-0.1	0.9	0.0	-0.2	-1.3
Diabetes (mother)	0.3	0.4	1.8	-1.0	-0.0	-0.7	-0.2	0.2	-0.3	-0.3	-1.3	-0.6
Severe depression (siblings)	1.6	1.8	11.7	-0.7	1.8	0.0	-0.3	0.3	3.4	-0.3	-0.6	-0.5
Pack years adult smoking proportion	0.6	0.9	3.0	-0.2	-0.7	-0.8	-0.8	-0.7	0.5	-0.6	-1.5	-1.7
Impedance of leg (right)	0.5	2.6	9.9	1.5	-0.6	0.2	-1.8	-3.1	0.9	0.1	-1.7	-2.0
Leg fat-free mass (left)	1.4	7.5	17.1	-1.0	0.5	0.1	4.0	4.1	-1.1	0.5	3.8	4.1
Trunk fat percentage	1.0	4.1	12.2	-1.4	-0.8	-1.3	2.8	2.9	1.1	-0.2	1.8	3.5
Hand grip strength (right)	0.2	0.4	1.4	0.5	-0.2	1.2	0.8	0.2	-1.0	-0.1	0.4	0.7
Townsend deprivation index at recruitment	1.4	1.9	7.7	-0.7	0.3	-1.2	1.2	2.0	-0.1	-0.4	1.5	2.8
Current tobacco smoking	2.2	3.6	9.2	-0.0	0.6	-1.5	-2.4	-1.5	0.7	-1.7	-3.0	-3.0
Average weekly fortified wine intake	0.8	0.9	2.5	1.2	0.8	0.0	-1.5	-0.8	-0.3	0.3	-0.7	-1.6
Maternal smoking around birth	0.4	0.6	3.0	-0.8	-1.7	-0.6	0.7	0.5	0.1	0.3	0.3	0.6
Fed-up feelings	1.5	2.7	8.1	0.3	-0.1	-2.3	-2.9	-0.5	1.0	-2.5	-1.4	-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	2.4	-0.7	-0.0	-0.0	-0.6	-1.6	0.6	-0.4	-0.3	0.2
Relative age voice broke	1.4	2.1	4.8	2.2	-0.3	-2.1	-1.6	-1.5	-0.5	-1.7	-1.2	-0.5
Taking other prescription medications	1.2	1.8	6.3	0.4	0.9	-1.8	-1.8	-0.8	1.1	-0.4	-0.9	-2.5
Age when periods started (menarche)	0.3	0.7	2.9	0.1	-0.4	0.0	0.9	0.5	-0.9	0.3	1.7	0.8
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	1.0	-0.3	0.2	-0.1	-0.5	-1.0	0.5	-0.8	-0.3	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	2.7	0.3	-0.3	-1.7	0.1	-1.3	-1.5	-1.0	-0.1	0.6
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.6	0.6	-0.3	-0.0	0.6	0.8	-0.2	0.2	0.0	0.7
Qualifications: CSEs or equivalent	1.1	1.4	3.3	-1.1	-0.5	-1.2	0.2	1.6	-1.6	-1.2	0.1	1.8
Serious illness, injury or assault to yourself	1.7	2.0	6.4	1.7	0.1	-0.5	-2.0	-1.8	1.1	0.3	-0.3	-2.5
High blood pressure	0.7	1.9	7.5	0.2	1.2	-0.9	-1.7	-0.8	-2.7	-1.0	-1.4	-0.9
Hayfever, allergic rhinitis or eczema	0.4	1.0	4.0	-0.7	0.6	-1.2	-0.5	0.7	-0.0	-2.0	-0.7	1.1
Multivitamins +/- minerals	0.5	0.6	1.8	-1.2	1.0	-0.4	0.8	1.3	0.6	0.0	0.5	0.1
Stomach or abdominal pain in last month	1.7	2.1	7.0	0.1	-0.5	-0.7	-1.9	-1.6	1.2	-0.5	-1.9	-2.6
Supplements: Glucosamine	0.3	0.3	1.7	0.2	0.2	-0.6	-0.2	-0.6	-1.3	0.3	-0.2	-0.7
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	2.3	0.4	0.2	0.1	1.0	0.4	1.5	0.3	0.8	0.7
Medication: Atenolol	0.3	0.4	1.1	0.7	1.0	-0.4	-0.7	0.5	0.0	-0.6	-0.4	-0.6
Medication: Levothyroxine sodium	0.8	1.3	6.2	0.5	-2.5	-1.7	-0.6	-0.0	0.8	-0.8	-0.9	-0.5
Sitting height	0.5	3.3	9.0	2.3	1.2	0.2	3.0	-0.7	0.1	0.3	3.0	2.2
Chronic bronchitis/emphysema (father)	1.0	1.2	5.8	0.3	-0.7	-0.3	-0.8	-0.4	2.4	-0.5	-1.5	-1.1
High blood pressure (mother)	0.8	1.1	5.7	-1.7	0.5	0.9	-0.4	0.1	-2.4	0.6	-0.4	-0.2
Body mass index (BMI)	0.9	3.8	16.3	-2.9	0.1	-0.9	1.8	4.0	0.7	-0.3	0.6	2.2
Impedance of leg (left)	1.1	5.2	15.5	2.4	-1.4	-0.7	-2.8	-3.9	1.0	-0.8	-2.6	-2.6
Leg predicted mass (left)	1.3	7.0	15.9	-0.9	0.4	0.1	3.9	4.0	-1.0	0.5	3.7	4.0
Trunk fat mass	1.1	4.7	12.9	-1.2	-0.7	-1.5	3.0	3.2	0.7	-0.3	2.2	3.6
Waist circumference	0.9	3.3	12.7	-2.1	0.3	-1.1	2.0	3.6	0.7	-0.5	0.9	2.4
Number of incorrect matches in round	1.0	1.6	5.3	-1.8	0.2	0.8	1.1	-0.9	1.7	2.3	0.5	0.7
Past tobacco smoking	0.7	1.3	3.6	-0.6	0.6	1.3	-1.4	-1.7	-1.9	0.1	-0.5	-0.9
Alcohol usually taken with meals	1.2	1.9	4.6	1.9	0.3	-0.7	0.7	2.1	-0.8	-0.6	2.1	1.4
Nervous feelings	0.1	0.1	0.7	-0.4	-0.0	0.9	0.1	0.3	-0.4	0.2	0.2	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	1.9	-1.4	0.2	0.1	-0.8	0.6	0.9	-0.9	-1.1	0.3
Hearing difficulty/problems with background noise	0.6	0.9	2.4	-1.0	1.2	-0.0	-0.6	0.4	1.6	-0.2	-1.0	-1.2
Hair/balding pattern: Pattern 2	0.6	0.8	2.0	0.6	1.1	0.8	0.4	-0.8	0.7	1.4	1.1	0.8
Had menopause	0.4	0.5	1.1	1.1	-0.8	0.6	-0.6	-0.7	0.2	0.5	-0.6	-1.0
Had other major operations	0.9	1.1	2.5	-1.6	0.3	-0.0	-0.4	-1.3	1.6	0.6	-1.1	-1.0
Forced vital capacity (FVC)	1.1	4.1	13.0	3.1	0.5	1.6	2.0	-0.7	-1.4	1.7	3.6	1.5
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	2.3	1.1	-0.6	-0.5	1.0	-1.4	-1.5	0.2	1.1	1.4
Ever unenthusiastic/disinterested for a whole week	5.0	6.1	12.6	-2.1	3.0	2.7	2.6	3.5	1.0	2.0	2.2	2.3
Qualifications: None of the above	0.3	0.7	4.2	-1.0	-0.3	0.3	0.6	-0.4	2.0	0.7	-0.1	0.2
Financial difficulties in last 2 years	0.6	0.7	4.3	-2.1	0.5	0.4	-1.2	-0.5	0.2	-0.4	-0.4	0.2
Mouth/teeth dental problems	0.8	1.3	2.9	1.7	-1.4	0.0	-0.8	-1.7	0.6	-0.0	-0.8	-1.6
Heart attack	0.4	0.5	1.8	0.5	1.3	-0.6	-0.8	0.1	-0.0	-0.3	-1.0	-0.1
Allergy	1.0	2.2	5.8	0.0	-0.4	2.2	1.8	0.7	-0.2	2.4	2.2	0.5
Pain all over the body in last month	1.6	1.7	7.3	-0.8	2.7	1.0	0.8	-1.0	-1.0	1.6	0.9	0.1
Diabetes (self-reported)	1.1	1.7	3.2	0.0	-0.5	-1.8	-1.0	1.8	-1.0	-1.7	-1.8	-0.8
Hayfever/allergic rhinitis (self-reported)	1.1	1.4	6.2	-2.5	0.6	-0.5	0.7	1.1	0.7	-0.4	0.7	1.8
Medication: Ramipril	0.7	0.9	1.9	-1.1	-0.6	-0.4	-0.6	1.3	-1.4	-0.0	-1.1	-0.9
Medication: Simvastatin	0.9	1.3	4.3	-1.2	0.6	0.1	-1.3	-0.1	-0.4	0.5	-2.0	-2.1
Fluid intelligence score	0.8	1.6	6.1	2.5	0.1	-0.5	-1.5	-0.8	-1.7	-0.1	0.1	-1.5
Illnesses of siblings	0.5	0.6	1.9	0.7	-0.2	-0.8	0.2	-1.1	1.4	-0.1	1.1	0.4
Neuroticism score	0.6	1.2	4.7	-0.6	0.3	-0.7	-2.2	0.4	0.5	-1.3	-1.2	-1.3
Weight	0.9	4.4	11.1	-1.3	-0.1	-1.0	3.0	3.3	-0.0	-0.1	2.4	3.3
Impedance of arm (right)	0.2	1.1	5.6	1.6	-0.6	-0.4	0.5	-2.4	0.4	0.1	0.4	0.7
Arm fat percentage (right)	1.1	4.2	11.8	-1.9	-0.8	-1.5	2.6	3.4	1.0	-0.5	1.3	3.1
Trunk fat-free mass	0.4	2.1	6.4	0.4	0.2	-0.3	2.1	2.0	-1.0	0.2	2.5	1.7
Hip circumference	0.7	3.1	7.3	-1.4	-0.2	-0.9	2.2	2.7	-0.5	-0.0	2.2	2.7
Time employed in main current job	1.1	1.2	4.6	-0.7	-1.3	-0.7	-0.2	-0.1	1.8	-0.6	-2.2	-0.1
Alcohol intake versus 10 years previously	3.3	5.0	9.2	1.9	0.6	-2.2	-3.0	-1.6	2.6	-2.0	-2.1	-3.0
Father’s age at death	0.2	0.3	1.3	0.6	0.1	-0.6	0.3	0.2	-0.1	0.6	1.1	-0.5
Worrier / anxious feelings	0.8	1.4	3.6	0.3	0.2	-0.6	-1.9	0.4	0.7	-1.9	-1.9	-1.2
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	3.2	-1.8	1.2	0.3	-1.0	-0.0	0.7	-0.0	-1.1	-0.4
Falls in the last year	0.3	0.4	1.3	-0.9	0.1	-0.2	-1.1	0.1	0.0	0.5	-0.2	-1.2
Hair/balding pattern: Pattern 3	0.6	1.0	4.0	1.0	-0.9	-1.0	-0.3	1.1	0.0	-2.0	-0.5	0.5
Number of live births	0.7	1.0	4.4	-0.9	-0.8	0.1	-0.2	0.5	2.1	-0.3	-1.6	-0.2
Forced expiratory volume in 1-second (FEV1)	1.4	4.6	14.9	2.8	0.1	2.0	2.0	-0.0	-1.6	1.9	3.9	2.2
Pulse rate	0.8	1.3	4.2	-2.0	0.5	1.5	0.9	1.0	1.0	0.9	0.2	1.3
Happiness	0.7	0.8	1.8	-1.1	-0.4	-0.7	-0.2	-1.3	0.8	-1.3	-0.3	1.1
Noisy workplace	0.9	1.1	4.8	-0.3	-0.7	-0.9	-0.8	0.1	-0.3	-1.2	-2.2	-1.2
Qualifications: A levels/AS levels or equivalent	0.3	0.7	1.6	1.2	-1.3	-0.8	-0.5	0.4	-0.8	-1.0	-0.1	-0.2
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	1.0	-0.8	0.4	0.6	-0.2	0.5	1.0	0.2	0.3	-0.0
Mouth/teeth dental problems: Dentures	0.6	1.0	2.4	0.6	1.3	-1.5	-1.1	0.7	-0.7	-1.6	-0.5	-0.4
Asthma	0.5	1.1	4.4	0.1	0.6	-0.7	-0.7	-0.1	0.8	-1.6	-2.1	-0.8
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.2	3.5	-1.9	1.5	1.2	0.6	0.9	0.9	0.7	0.5	1.0
Medication: Cholesterol lowering	0.7	1.1	3.6	0.2	0.4	-1.1	-1.4	-1.1	-0.8	0.4	-1.1	-1.9
Depression (self-reported)	0.3	0.4	1.8	-0.2	1.4	-0.4	-0.3	-0.4	0.5	-0.2	0.6	0.6
Medication: Lansoprazole	0.5	0.6	3.0	-0.8	1.7	-1.0	-0.0	-0.1	0.3	-0.1	-0.5	0.2
Prospective memory result	0.8	1.0	2.9	0.1	-0.9	-1.7	-0.2	-0.6	-0.1	-1.7	-1.0	1.2
Lung cancer (father)	2.3	2.7	7.7	-2.1	-0.7	-0.2	1.9	2.8	0.6	-0.7	0.5	2.7
Illnesses of mother	1.3	1.6	7.8	0.8	-0.4	-0.6	0.9	1.6	2.8	-1.0	0.2	1.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.6	9.3	2.4	0.4	2.0	1.7	-0.1	-2.1	1.9	3.0	1.6
Pulse wave Arterial Stiffness index	0.4	0.4	2.2	-0.6	-0.0	0.1	-0.4	-1.5	-0.6	0.7	-0.1	-0.7
Impedance of arm (left)	0.3	1.2	5.6	1.8	-0.6	0.1	0.6	-2.4	-0.2	0.3	0.7	1.0
Arm fat mass (right)	1.1	4.7	15.0	-1.9	-0.6	-1.5	2.7	3.9	0.7	-0.5	1.6	3.2
Trunk predicted mass	0.4	2.1	6.6	0.4	0.2	-0.2	2.2	1.9	-1.0	0.3	2.6	1.6
Standing height	0.5	4.7	14.6	3.4	-0.7	-0.4	2.8	-1.1	-1.2	0.3	3.8	2.3
Length of working week for main job	0.9	1.0	2.5	1.5	-1.6	-0.7	0.5	-0.7	-0.2	0.1	1.6	1.0
Exposure to tobacco smoke at home	2.3	2.5	4.2	-1.4	1.6	1.5	2.0	1.6	0.4	1.5	2.0	1.8
Breastfed as a baby	0.9	1.2	2.6	1.2	-1.2	-1.6	0.8	0.0	-0.6	-0.4	1.5	1.2
Tense / ‘highly strung’	1.1	1.8	8.0	-1.2	0.6	2.8	0.9	1.7	0.5	1.3	0.7	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	2.9	-1.0	0.9	-0.8	-1.1	-0.8	1.7	-0.3	-0.3	-0.6
Hair/balding pattern: Pattern 4	0.4	0.9	3.1	1.1	-0.4	-0.5	0.0	0.7	-1.8	0.0	1.8	0.4
Birth weight of first child	0.4	0.7	1.8	-0.4	1.3	0.4	0.9	0.9	0.4	0.6	1.3	0.4
Peak expiratory flow (PEF)	1.3	3.0	6.6	1.8	-0.8	1.0	1.6	2.3	-1.1	0.0	2.5	2.6
Pulse wave reflection index	0.6	0.7	2.5	0.6	0.4	1.0	0.1	-0.7	-1.6	0.9	0.2	-1.2
Ever highly irritable/argumentative for 2 days	1.3	1.5	3.1	-1.7	1.0	1.8	1.2	0.0	-1.6	1.1	-0.1	1.3
Loud music exposure frequency	2.4	2.6	6.4	0.7	-0.5	-1.6	-2.3	-1.4	0.3	-2.5	-2.3	-1.0
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	2.4	1.1	-1.4	-1.4	-1.5	-0.4	-1.4	-1.3	-0.6	-0.5
Mouth/teeth dental problems: Bleeding gums	1.2	1.6	6.3	-1.5	0.1	0.1	1.1	1.6	-0.7	-0.0	1.1	2.5
Blood clot in the leg (DVT)	0.7	0.9	2.1	1.3	0.3	-1.2	-1.0	-1.5	-1.1	-0.4	0.1	-0.1
Medication: Paracetamol	0.9	1.6	3.6	-0.3	1.0	-0.7	-1.5	-1.3	0.8	-1.2	-1.9	-1.7
Headache pain in last month	1.7	2.9	6.5	0.1	0.0	-1.2	-2.0	-0.7	2.5	-2.3	-2.6	-1.4
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	1.9	0.5	-1.0	1.4	0.9	0.2	0.6	0.0	0.7	1.2
Glaucoma (self-reported)	0.5	0.5	1.6	-1.3	-0.7	0.4	0.7	1.0	0.8	0.0	0.5	-0.0
Gout (self-reported)	0.6	0.9	3.7	-1.4	0.9	-0.4	-0.1	0.9	1.9	-0.4	-0.1	-0.5
Hypothyroidism/myxoedema (self-reported)	0.9	1.8	4.2	-1.2	-2.1	-0.3	1.3	1.6	2.0	0.3	0.3	1.4
Medication: Amlodipine	1.7	2.4	8.6	-2.9	1.3	1.6	-0.0	1.2	-2.4	0.8	-0.9	0.5
Medication: Ventolin 100micrograms inhaler	0.8	1.0	3.8	-0.3	-0.7	-1.0	-0.1	1.7	-0.4	-2.0	-0.8	0.4
Birth weight	0.5	1.0	2.7	-0.4	-0.2	1.1	1.4	1.6	0.6	1.2	1.1	0.6
Chronic bronchitis/emphysema (mother)	0.5	0.5	1.2	-0.6	1.0	0.1	-0.2	-0.1	0.9	0.0	-1.1	-1.1
High blood pressure (siblings)	0.5	0.8	2.8	-0.1	-0.4	-0.0	-1.2	0.3	-1.2	-0.3	-1.7	-0.8
Forced vital capacity (FVC), Best measure	0.8	3.1	8.5	2.9	0.7	1.5	1.8	-0.6	-1.4	1.5	2.7	1.2
Body fat percentage	0.9	3.6	9.4	-1.7	-0.8	-1.2	2.4	3.1	1.3	-0.2	1.2	2.9
Leg fat percentage (right)	0.7	2.5	8.6	-2.6	-0.2	-0.6	1.5	2.9	1.5	0.1	0.1	1.6
Arm fat-free mass (right)	0.6	3.3	7.7	-0.4	0.4	0.3	2.5	2.8	-0.8	0.5	2.8	2.5
Exposure to tobacco smoke outside home	0.7	0.9	2.2	-1.5	-0.5	-0.6	-0.0	1.4	0.9	-1.2	-0.9	0.7
Comparative body size at age 10	0.3	0.8	2.9	-1.7	-0.0	-0.0	0.3	1.2	-0.6	0.1	1.0	1.4
Number of full brothers	0.9	1.2	3.5	0.2	-1.9	-1.1	-0.9	-0.8	1.6	-1.0	-0.6	-0.5
Worry too long after embarrassment	0.9	1.5	4.3	0.3	-0.8	-1.4	-1.9	1.0	-0.8	-2.1	-0.5	-1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.7	3.2	-0.9	0.0	-0.1	-1.0	-1.8	-0.0	0.0	-0.5	-1.1
Wheeze or whistling in the chest in last year	1.3	2.3	7.5	-2.7	2.6	1.0	0.1	0.1	1.6	1.2	-0.6	-0.8
Number of children fathered	1.3	1.4	5.1	0.3	-0.6	-0.3	-1.4	-1.4	1.2	-0.3	-1.5	-2.2
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	2.8	-1.7	-0.7	-0.8	-0.1	1.4	-0.7	-0.4	-1.4	0.1
Age at first live birth	1.3	2.4	6.3	2.5	-0.6	0.3	-2.2	-1.4	-1.8	-0.7	-0.8	-1.8
Pulse wave peak to peak time	0.5	0.5	1.7	1.0	-0.1	-0.3	0.5	1.3	0.6	-0.9	0.3	0.8
Health satisfaction	0.9	1.2	4.6	-1.8	2.1	0.5	0.8	-0.2	0.5	0.9	0.9	0.6
Shortness of breath walking on level ground	0.8	1.0	4.0	-1.8	2.0	0.4	0.3	0.7	0.9	0.2	-0.4	-0.2
Qualifications: College or University degree	0.4	1.4	9.3	3.0	0.6	0.5	0.1	-0.3	0.8	0.4	1.1	-0.6
Eye problems/disorders: None of the above	0.8	0.9	1.8	0.7	0.9	-0.9	-1.2	-1.3	0.5	-0.9	-1.3	-0.3
Mouth/teeth dental problems: Loose teeth	0.9	1.1	2.9	-0.3	0.3	1.2	1.7	0.7	0.0	1.4	1.4	0.9
Emphysema/chronic bronchitis	0.6	0.6	4.0	-0.1	-0.8	-0.7	0.4	-0.5	2.0	0.0	0.0	0.3
Medication for pain relief, constipation, heartburn	1.0	1.8	4.3	0.4	-0.4	1.2	1.9	2.1	0.2	0.8	1.5	1.8
Neck or shoulder pain in last month	1.8	2.6	12.5	-0.9	1.3	-0.9	-1.8	-0.0	3.5	-0.7	-1.1	-1.7
Medication: Blood pressure	0.9	1.5	6.4	-0.7	1.6	-1.1	-0.8	1.1	-2.5	-0.6	-0.9	-0.3
Angina (self-reported)	1.3	1.7	4.6	-0.7	-0.1	-1.6	-1.2	1.7	0.8	-1.4	-2.1	-0.9
Migraine (self-reported)	0.2	0.3	1.0	-0.4	1.0	0.1	-0.1	0.2	0.8	-0.4	-0.8	0.2
Medication: Ibuprofen	0.4	0.4	1.2	-1.1	0.9	0.2	-0.1	0.9	0.8	-0.1	-0.3	0.6
Medication: Allopurinol	0.4	0.6	2.4	-0.7	0.6	-0.3	0.0	1.2	1.6	-0.1	0.4	-0.3
Medication: Omeprazole	1.7	2.0	4.0	1.0	-0.2	-1.2	-1.9	-1.3	2.0	-1.6	-1.5	-1.3
Medication: Seretide 50 evohaler	0.9	1.1	3.7	-1.1	0.6	1.2	1.2	0.8	1.9	0.7	-0.0	0.3
Mean time to correctly identify matches	0.5	0.9	2.4	-0.6	-0.3	0.8	-0.1	-1.4	0.0	1.6	-0.7	-1.3
Heart disease (mother)	0.7	0.9	4.4	0.2	-0.2	0.8	0.0	-0.7	-1.1	2.1	0.2	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	3.5	-1.9	0.6	0.8	-0.0	1.2	-0.2	0.3	-0.5	0.2
Whole body fat mass	1.0	4.3	12.2	-1.6	-0.8	-1.6	2.6	3.5	0.7	-0.5	1.6	3.2
Leg fat mass (right)	1.1	4.1	14.5	-2.4	-0.4	-1.0	2.4	3.8	0.9	-0.2	1.2	2.8
Arm predicted mass (right)	0.6	3.3	7.8	-0.5	0.4	0.2	2.4	2.8	-0.9	0.5	2.8	2.6
Pulse rate, automated reading	0.5	1.6	4.2	-1.9	1.7	2.0	-0.7	-0.9	0.8	1.2	-0.4	-0.4
Alcohol intake frequency.	0.5	1.3	3.7	-0.3	1.9	-0.9	-1.4	-1.0	0.9	-1.4	-0.7	-0.8
Comparative height size at age 10	0.4	2.0	7.6	1.9	-0.3	0.7	1.6	0.3	-1.6	0.7	2.8	0.6
Number of full sisters	0.5	0.5	2.1	-0.6	1.4	-0.6	-0.5	0.5	0.7	-0.6	-0.9	0.0
Suffer from ‘nerves’	0.3	0.5	1.7	0.2	-0.3	-0.2	-1.3	-0.0	-1.0	-1.1	-0.4	-0.8
Overall health rating	1.1	2.4	4.1	-1.2	1.9	-1.7	-1.6	-1.9	2.0	-0.8	-0.9	-1.3
Chest pain or discomfort	0.5	0.7	3.3	-1.8	0.4	0.4	-0.1	-0.0	1.4	-0.0	-0.5	-0.3
Had major operations	0.4	0.4	1.5	0.7	-0.2	-1.2	-0.5	-0.5	-0.3	-1.1	0.0	-0.4
Age at last live birth	0.6	0.9	2.5	1.6	-0.0	0.4	-1.3	-1.4	0.3	-0.7	-1.0	-0.1
Family relationship satisfaction	0.3	0.4	1.0	-0.9	-0.8	0.3	-0.5	-1.0	0.4	-0.3	-0.6	0.1
Leg pain on walking	0.7	0.9	3.5	-1.5	1.1	-0.3	0.4	-0.6	1.9	0.1	0.4	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.0	3.9	0.6	2.0	0.5	0.3	1.5	-0.0	0.4	1.6	0.1
Commuting to job workplace: Car/motor vehicle	1.0	1.1	3.1	-1.1	0.5	1.2	0.5	-0.6	1.2	1.8	0.3	-1.4
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	4.2	1.0	-0.4	0.9	2.0	0.2	0.4	1.2	1.2	0.9
Medication: Aspirin	0.7	0.9	2.0	0.5	-1.3	-1.1	-0.9	-0.6	-1.4	-0.5	-0.7	-1.0
Supplements: Vitamin C	1.5	1.8	5.3	-1.3	0.2	0.9	2.3	1.7	-0.9	0.6	0.9	1.9
Knee pain experienced in last month	0.3	0.4	1.7	-1.3	1.1	-0.1	-0.0	0.5	0.6	-0.1	0.5	0.0
Hypertension (Self-reported)	0.6	1.8	8.4	0.1	1.2	-1.0	-1.4	-0.5	-2.9	-1.0	-1.3	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.0	-0.6	-0.5	-0.7	0.0	-0.1	1.0	-0.7	-0.8	-0.4
Illnesses of father: Heart disease	0.3	0.4	1.6	0.1	-0.6	-1.3	-0.4	-0.7	0.1	-0.9	-0.7	0.0
Illnesses of siblings: Diabetes	0.9	1.1	2.7	-0.5	0.7	-1.6	-0.8	0.3	-0.5	-1.1	-1.6	-1.2
Smoking status: Previous	1.1	1.6	4.8	-0.2	0.0	-0.1	2.2	1.6	1.3	1.2	1.5	1.3
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	3.3	-0.7	1.7	0.6	1.8	1.2	-1.3	-0.3	1.2	1.6
Whole body fat-free mass	0.7	3.8	9.3	-0.2	0.2	-0.1	2.9	2.9	-0.9	0.3	3.0	2.7
Leg fat-free mass (right)	1.1	6.0	14.6	-0.5	-0.0	-0.4	3.5	3.7	-1.1	-0.0	3.4	3.8
Arm fat percentage (left)	1.2	4.9	13.9	-2.0	-0.6	-1.2	2.9	3.7	0.8	-0.2	1.6	3.5
Average weekly red wine intake	0.4	0.5	1.2	0.8	0.9	-0.0	0.5	1.1	-0.4	-0.4	1.1	0.6
Handedness (chirality/laterality): Left-handed	0.4	0.5	2.2	0.2	-0.3	-1.4	-0.3	-0.6	-0.2	-1.5	-0.4	-0.1
Mood swings	0.5	0.9	2.5	-1.1	1.3	-0.6	-1.6	-0.1	0.7	-0.8	-0.9	-0.8
Loneliness, isolation	0.3	0.4	1.8	-0.1	0.3	-0.9	-1.1	-0.1	0.3	-1.3	0.1	-0.1
Long-standing illness, disability or infirmity	1.1	1.6	4.1	-2.0	0.4	-0.6	-1.3	-0.4	1.4	0.1	-1.6	-1.9
Ever had bowel cancer screening	1.1	1.2	2.1	-1.0	0.9	1.0	-0.2	-1.5	1.1	1.3	-1.2	-1.4
Diabetes diagnosed by doctor	0.5	0.8	2.1	-0.5	-0.0	-1.1	-0.6	1.3	-0.4	-1.0	-1.4	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	2.0	0.7	-0.1	-0.6	-0.4	0.7	-1.4	-0.5	-0.6	-0.3
Friendships satisfaction	0.7	0.9	2.9	-1.1	0.7	-0.0	1.1	-0.9	-0.9	-0.1	0.7	1.7
Qualifications: nursing, teaching	1.0	1.6	7.6	2.8	-0.5	-1.2	-0.5	1.0	-1.6	-1.2	-0.1	-0.3
Commuting to job workplace: Walk	0.2	0.3	0.8	-0.8	-0.2	0.2	-0.0	0.4	0.9	-0.5	0.0	0.6
Eye problems/disorders: Cataract	0.6	0.7	2.3	-1.1	-0.3	0.8	1.0	1.5	-0.3	0.5	0.5	0.9
Mouth/teeth dental problems: Mouth ulcers	1.6	2.5	5.1	-2.3	0.4	2.2	1.9	0.3	1.5	2.1	1.0	1.0
Medication for cholesterol	0.6	1.0	3.4	1.2	0.2	-1.1	0.3	0.3	1.8	0.3	1.5	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	3.4	-0.6	0.1	1.2	1.4	-0.3	1.1	1.8	1.8	0.3
Back pain experienced in last month	3.0	4.4	25.6	-1.8	2.9	-0.0	-0.7	0.6	5.1	-0.7	-0.8	-0.6
Mineral and other dietary supplements	0.5	0.6	3.6	1.9	0.3	0.3	-0.9	-0.7	-0.4	-0.3	0.4	-0.2
Breast cancer (self-reported)	0.5	0.6	2.6	1.6	-0.6	-0.2	-0.6	-0.6	0.4	0.2	0.5	-1.1
Asthma (self-reported)	0.4	0.8	3.3	-0.0	0.9	-0.3	-0.2	-0.1	1.2	-1.3	-1.8	-0.4
Osteoporosis (self-reported)	0.5	0.6	1.7	0.1	0.0	-0.4	-0.9	-1.3	-1.2	-0.4	-1.1	-0.5
Osteoarthritis (self-reported)	0.3	0.4	0.8	-0.9	0.7	-0.9	0.3	0.5	0.6	-0.2	0.8	0.4
Medication: Aspirin	0.6	0.7	3.2	0.0	-0.8	-0.9	-0.9	-0.1	-1.8	-0.5	-0.5	-0.8
Medication: Gliclazide	1.1	1.2	3.0	-1.6	-1.5	-0.7	0.7	1.7	-0.1	-1.0	-1.2	0.1
Illnesses of father: None of the above (group 1)	0.9	1.1	3.7	-0.6	0.3	-0.3	1.3	1.2	-0.4	-0.2	1.5	1.9
Smoking status: Current	2.0	3.2	9.4	0.1	0.5	-1.6	-2.1	-0.8	1.1	-1.8	-3.1	-2.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.3	4.9	14.6	-0.9	1.7	3.2	2.4	1.0	-0.2	3.8	2.5	1.4
Whole body water mass	0.7	4.2	10.4	-0.2	0.2	-0.0	3.0	2.9	-1.0	0.4	3.2	2.8
Leg predicted mass (right)	1.1	5.9	14.2	-0.4	0.1	-0.3	3.4	3.7	-1.1	0.0	3.5	3.8
Arm fat mass (left)	1.3	5.2	15.5	-2.0	-0.5	-1.3	3.0	3.9	0.4	-0.2	2.1	3.5
Number of self-reported non-cancer illnesses	1.1	2.0	5.1	-1.1	0.4	-1.7	-1.9	-0.5	0.3	-1.2	-2.3	-1.7
Average weekly champagne plus white wine intake	1.3	1.8	6.1	1.9	0.4	-0.4	0.6	1.5	-0.8	0.3	2.5	1.6
Miserableness	0.3	0.6	1.9	-0.5	0.8	-0.6	-0.6	0.7	1.4	-0.8	0.4	0.6
Guilty feelings	0.3	0.5	2.3	-0.1	-0.1	-1.2	-0.9	0.1	-0.3	-1.5	-0.2	-0.4
Wears glasses or contact lenses	1.4	1.7	3.7	1.9	0.5	-1.5	-1.3	-1.7	0.8	-1.6	-0.1	-1.0
Ever taken oral contraceptive pill	1.7	1.9	5.1	-2.1	1.3	1.6	1.4	-0.2	-0.1	2.3	1.1	0.4
Hearing aid user	2.3	2.6	9.9	-0.0	0.0	0.8	-1.9	-2.2	1.4	1.0	-1.3	-3.1
Mother’s age at death	1.0	1.3	3.8	1.9	-0.3	0.1	-0.7	-1.7	-2.0	0.0	0.4	-0.5
Financial situation satisfaction	3.6	4.5	9.1	-3.0	1.6	2.5	2.2	-0.2	1.9	2.0	1.9	2.5
Tinnitus: Yes, now most or all of the time	0.6	0.7	1.5	0.5	0.8	-0.7	-0.9	-1.1	-0.5	-0.0	-1.2	-1.0
Commuting to job workplace: Public transport	0.5	0.6	1.8	-0.4	0.2	-1.1	-1.3	-0.0	-0.9	-1.0	-0.6	-0.6
Eye problems/disorders: Glaucoma	0.5	0.6	2.6	-1.4	-1.6	0.2	0.5	0.7	-0.1	-0.3	0.2	0.0
Medication: Blood pressure	1.3	2.5	7.8	0.5	1.2	0.6	-1.7	-2.1	-2.8	-0.8	-1.4	-1.7
Pain type(s) experienced in last month: Hip pain	0.7	0.9	2.3	-0.0	-0.1	-0.8	-1.4	-0.2	0.8	-0.9	-1.5	-1.3
Supplements: Fish oil (including cod liver oil)	0.3	0.3	1.2	-0.6	-0.0	-1.1	-0.2	-0.3	0.0	-0.3	-0.7	-0.8
High cholesterol (Self-reported)	0.5	0.9	3.3	-1.0	0.8	1.0	0.1	-0.7	0.3	1.8	-0.2	-1.1
Medication: Bendroflumethiazide	1.0	1.5	4.3	-0.2	0.7	-0.2	-1.4	-1.5	-2.1	-0.0	-1.2	-1.8
Medication: Paracetamol	1.2	1.8	3.5	-0.1	0.9	-1.3	-1.7	-1.3	0.8	-1.6	-1.9	-1.5
Medication: Lisinopril	1.5	1.9	8.4	-0.6	2.2	0.7	0.4	1.2	-2.9	0.1	0.6	1.1
Medication: Atorvastatin	0.5	0.7	3.2	0.4	0.0	-1.8	-0.4	0.2	-1.1	-1.1	-0.0	0.2
Illnesses of father: High blood pressure	0.5	0.6	1.5	-1.2	0.6	1.1	-0.0	0.6	-0.7	-0.7	-0.8	0.3
Alcohol drinker status: Never	1.8	2.1	4.4	-0.4	2.1	1.9	1.3	1.0	-0.9	1.5	1.8	1.3
Ever smoked	1.1	1.9	5.9	1.8	-1.1	-2.4	-0.2	1.1	1.5	-1.7	-0.7	-0.0
Basal metabolic rate	0.7	4.1	10.0	-0.4	0.0	-0.5	3.0	3.2	-0.8	0.1	3.0	2.9
Leg fat percentage (left)	0.5	1.9	6.4	-2.0	-0.5	-1.2	0.8	2.5	1.8	-0.4	-0.4	1.1
Arm fat-free mass (left)	0.5	2.7	7.5	-0.4	-0.0	-0.4	2.3	2.7	-0.6	0.1	2.3	2.3
Number of operations (self-reported)	1.0	1.5	5.4	1.2	-0.7	-2.3	-1.0	-1.0	0.5	-1.5	-1.1	-0.4
Average weekly beer plus cider intake	1.6	2.4	8.8	-1.0	-1.3	0.1	-1.3	-3.0	1.2	-0.4	-1.6	-2.0
Irritability	1.0	1.7	4.1	-1.2	1.1	0.4	-2.0	-0.7	1.7	-1.2	-1.9	-0.5
Risk taking	0.6	0.9	1.9	-1.1	1.2	1.1	1.0	1.4	0.3	1.1	0.2	0.8
Ever had prostate specific antigen (PSA) test	1.5	1.7	5.4	1.3	0.1	-0.6	-1.4	-2.2	0.4	-0.3	-0.8	-2.3
Fractured/broken bones in last 5 years	0.4	0.5	0.9	-0.3	-0.7	1.0	-0.7	-0.4	0.8	0.8	-0.0	-1.0
Age started oral contraceptive pill	1.2	1.5	8.2	1.5	-0.5	0.7	-0.7	-2.9	-0.8	0.6	0.0	-0.5
Diastolic blood pressure, automated reading	0.5	1.6	4.3	-0.9	2.1	1.7	0.9	-0.3	-1.8	1.5	0.4	0.3
Ever depressed for a whole week	4.0	5.0	8.6	-2.9	2.9	2.3	2.2	2.1	1.0	1.9	2.2	1.9
Unable to work because of sickness or disability	0.7	0.9	2.4	0.2	1.1	-0.2	-1.1	-1.6	-1.2	0.6	0.3	-1.1
Commuting to job workplace: Cycle	0.4	0.5	2.5	0.5	0.1	0.6	0.5	0.7	0.4	0.5	1.6	0.1
Myopia	0.7	1.1	6.0	0.6	0.6	0.6	-0.2	-1.2	2.5	0.4	0.1	-0.8
Vascular/heart problems diagnosed by doctor	0.5	1.5	5.5	-0.3	-1.1	0.9	1.6	0.5	2.3	1.0	1.2	0.7
Cholesterol lowering medication	0.4	0.6	2.5	-0.9	0.1	0.6	-0.8	0.2	-0.3	-0.0	-1.6	-1.0
Medication: Omeprazole (e.g. Zanprol)	4.1	5.0	9.2	1.6	-1.0	-2.4	-3.0	-2.6	1.6	-2.3	-2.5	-2.4
Pain experienced in last month	1.6	2.7	8.0	1.8	-2.8	0.3	1.6	0.3	-2.8	0.8	0.8	1.2
Supplements: Calcium	0.6	0.7	2.9	-0.5	-0.9	0.5	0.8	1.7	0.2	0.7	0.7	0.3
Basal cell carcinoma (self-reported)	1.5	1.8	5.1	1.9	-1.0	-1.9	-1.6	0.0	-0.6	-2.3	-0.1	-0.3
Heart attack/myocardial infarction (self-reported)	0.4	0.5	2.0	0.5	1.4	-0.8	-0.9	0.2	-0.1	-0.3	-0.9	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	2.0	1.3	0.7	-1.0	-1.1	-1.4	-0.7	-0.2	0.3	-0.4
Heart disease (siblings)	0.7	0.8	2.7	-0.4	1.6	1.1	-0.1	0.1	1.6	0.6	-0.5	-0.5
Alcohol drinker status: Previous	0.7	0.8	2.6	-0.5	1.6	-1.6	-0.5	-0.2	1.2	-0.4	0.4	0.3
Pack years of smoking	0.8	1.1	3.1	0.2	-1.2	-0.9	-0.8	-0.7	0.6	-0.7	-1.7	-1.7
Impedance of whole body	0.4	2.0	11.1	2.2	-0.8	-0.2	-1.0	-3.3	0.2	-0.2	-0.6	-0.5
Leg fat mass (left)	0.9	3.4	12.7	-2.0	-0.5	-1.3	2.0	3.6	1.1	-0.4	0.9	2.4
Arm predicted mass (left)	0.5	2.7	7.0	-0.4	-0.1	-0.4	2.3	2.6	-0.6	0.1	2.5	2.4