Hub : Genes

ZNF876P

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.3190 0.0580 3.3e-16 0.140 0.166 0.158 0.174 0.149 1.0e-16 9.7e-20 9.1e-19 1.3e-20 8.7e-18
2 GTEx Cells Transformed fibroblasts 0.0620 0.0310 9.0e-03 0.020 NA 0.026 NA 0.024 1.1e-02 NA 4.3e-03 NA 6.4e-03
3 GTEx Testis 0.0970 0.0450 5.4e-03 0.081 NA 0.071 NA 0.077 1.9e-04 NA 4.5e-04 NA 2.7e-04
4 ROSMAP Brain Pre-frontal Cortex 0.0449 0.0240 2.0e-02 0.037 0.008 0.015 0.021 0.034 1.4e-05 2.8e-02 4.4e-03 9.5e-04 2.6e-05
5 TCGA Colon Adenocarcinoma 0.2560 0.1100 2.3e-11 0.228 0.194 0.203 NA 0.228 2.5e-13 2.2e-11 6.8e-12 NA 2.5e-13
6 TCGA Head and Neck Squamous Cell Carcinoma 0.0816 0.0405 8.0e-08 0.056 0.064 0.068 NA 0.052 6.9e-07 1.0e-07 4.5e-08 NA 1.6e-06
7 TCGA Lung Squamous Cell Carcinoma 0.0395 0.0209 2.0e-05 0.050 0.050 0.045 NA 0.045 2.3e-06 2.2e-06 6.4e-06 NA 6.5e-06
8 TCGA Rectum Adenocarcinoma 0.2390 0.1180 4.0e-03 0.008 0.016 0.013 NA 0.031 2.1e-01 1.3e-01 1.6e-01 NA 6.3e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.5 0.7 4.1 -2.0 0.0 0.5 -0.9 0.0 0.3 0.3 -0.5
Bipolar Disorder or Schizophrenia 0.3 0.7 3.2 -0.7 -0.5 1.8 1.2 0.0 -0.3 0.6 -0.1
Depressed Affect (Nagel 2018) 1.0 2.1 4.4 -2.1 -1.1 -0.8 -0.8 2.1 1.8 1.2 0.9
Depression (Nagel 2018) 1.5 2.2 5.7 -0.0 -2.3 1.6 0.9 2.4 0.3 1.7 0.9
Intelligence (Savage-Jansen 2018) 2.1 6.6 12.8 2.2 2.0 -0.9 -0.9 -3.5 -2.8 -3.6 -2.9
Neuroticism (Nagel 2018) 0.8 1.9 4.3 -2.1 -1.2 -0.1 -0.3 1.7 1.7 1.2 1.4
Schizophrenia (2018) 0.6 1.3 5.3 0.6 -1.1 1.9 2.3 0.5 -0.1 0.1 0.2
Schizophrenia vs Biploar Disorder 0.1 0.1 0.7 0.2 0.0 0.8 0.1 0.0 0.0 0.0 -0.0
Worry (Nagel 2018) 1.2 2.6 6.8 -2.6 -1.0 0.2 0.4 2.6 1.3 1.8 1.1
Alzheimer’s Disease (in mother) 0.1 0.1 0.2 0.4 0.4 -0.1 -0.2 0.4 -0.4 0.4 0.0
Alzheimer’s Disease (in father) 1.8 2.0 3.9 -0.8 -1.1 -0.0 0.5 2.0 1.7 1.8 2.0
Alzheimer’s Disease (including proxy) 0.5 0.8 1.8 0.3 -0.8 0.8 0.7 1.3 0.4 1.2 1.0
Crohns Disease (2017) 0.9 2.0 5.2 -0.2 1.0 -1.6 -2.3 -0.8 -1.1 -1.4 -1.8
Irritable Bowel Disease (IBD) 0.4 0.8 2.8 0.7 -0.4 -1.2 -1.7 -0.5 -0.4 -0.9 -0.8
Ulcerative Colitis (UC) 0.2 0.4 1.1 0.7 -0.9 -0.7 -1.1 -0.2 -0.0 -0.5 0.1
Major Depression (MDD) 1.3 1.6 5.0 -2.2 -0.7 -0.3 0.4 1.7 1.4 1.4 0.7
Reaction Time 1.2 2.3 4.5 -1.0 -2.1 0.3 0.9 2.0 1.8 1.7 1.3
Verbal and Numeric Reasoning (VNR) 1.4 3.5 7.6 2.0 0.7 0.2 0.0 -2.7 -2.2 -2.7 -1.9
Breast Cancer 0.3 0.6 1.6 0.6 0.6 -0.9 -0.5 -1.1 -1.3 -0.6 -0.5
Ovarian Cancer 0.9 1.2 3.8 0.7 -0.9 1.9 1.9 0.3 -0.8 0.4 0.1
Prostate Cancer 0.3 0.4 1.2 -0.6 0.1 -1.1 -0.4 0.4 1.0 0.2 0.6
Age at First Birth 0.3 0.4 1.0 -0.6 0.6 1.0 0.3 -0.9 -0.5 -0.5 0.4
Bipolar Disorder (2011) 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3
Body Mass Index (BMI) (2010) 0.8 1.1 2.0 0.2 -1.1 0.5 0.8 1.4 0.8 1.4 1.4
Coronary Artery Disease (CAD) 0.5 0.6 3.6 1.9 -0.3 -0.1 -0.2 0.1 1.0 -0.3 0.1
Crohns Disease (2012) 0.8 1.2 3.8 1.1 -0.7 0.5 -0.5 -0.5 -1.3 -1.4 -1.9
Mean Putamen Volume 0.4 0.4 1.4 0.2 -1.2 0.4 1.1 0.5 0.5 0.2 0.2
Fasting Glucose 1.1 1.3 3.5 0.1 1.9 -1.7 -1.7 0.1 -0.9 0.1 -0.0
HbA1C 4.5 5.0 7.7 0.4 2.8 -2.6 -2.6 -2.1 -1.9 -2.1 -2.5
HDL Cholesterol 0.6 1.1 1.7 1.3 0.4 -0.6 -0.1 -1.3 -1.1 -1.3 -1.3
LDL Cholesterol 1.1 1.7 4.0 -0.5 2.0 -1.4 -1.2 -1.5 -1.0 -1.4 -1.0
Lupus 0.2 0.2 0.8 0.3 0.9 -0.7 -0.0 -0.6 -0.4 0.1 -0.1
Neuroticism (2016) 0.8 1.1 4.3 -2.1 -0.5 -0.1 -0.0 1.5 1.0 0.6 0.9
Primary Biliary Cirrhosis 1.3 1.9 3.4 -0.9 -1.4 1.3 1.4 1.8 1.8 0.9 1.0
Rheumatoid Arthritis 1.3 1.7 4.6 -1.6 -0.1 0.4 -0.3 1.7 2.1 1.2 1.4
Schizophrenia (2014) 0.2 0.5 1.7 -0.2 -1.0 1.2 1.3 0.0 0.0 0.0 0.1
Triglycerides 0.9 1.4 5.0 -0.5 1.5 -2.2 -1.8 -0.6 -0.5 -0.1 -0.2
Type 2 Diabetes (T2D) (2012) 0.4 0.4 1.2 -0.1 1.1 -1.0 0.0 -0.2 1.0 -0.6 0.1
Ulcerative Colitis 0.3 0.4 2.0 0.2 0.1 -0.5 -1.4 -0.2 0.0 -0.8 -0.5
Blood Eosinophil Count 0.0 0.2 0.5 0.5 0.1 -0.7 -0.4 0.4 0.7 -0.1 -0.1
Blood Platelet Count 0.0 0.5 1.6 -0.2 -0.4 1.2 0.2 0.9 0.8 0.7 0.5
Blood Red Count 0.4 3.7 8.1 -0.2 2.1 -0.2 -0.5 -2.7 -2.8 -2.2 -2.1
Blood White Count 0.6 4.4 6.9 -0.1 -2.1 2.2 2.6 2.6 1.1 2.5 2.3
Heel T-Score 1.8 14.0 27.9 -4.4 -0.0 -0.3 -1.5 5.3 5.2 4.7 3.7
BMI 0.4 2.1 4.5 1.3 0.3 -0.1 -0.2 -2.1 -1.5 -2.0 -2.1
Height 0.4 6.8 13.4 1.6 3.7 -3.1 -2.3 -3.1 -1.9 -2.6 -2.0
Waist Hip Ratio (WHR) 0.3 1.5 3.6 -0.4 1.5 0.6 -0.1 -0.7 -1.6 -1.5 -1.9
Systolic Blood Pressure 0.0 0.2 1.2 -0.3 0.2 -1.1 -0.4 -0.4 -0.1 -0.3 -0.1
Smoking Status 1.2 3.0 6.0 0.0 -1.7 0.8 0.4 2.3 2.5 1.9 2.3
Allergy or Eczema 0.3 0.7 1.6 -1.3 0.5 -1.1 -1.2 0.1 0.9 0.1 0.2
Cardiovascular Disease 0.1 0.3 0.8 -0.9 0.7 -0.2 -0.5 0.1 -0.3 -0.3 -0.8
Hypothyroidism (self reported) 2.9 6.6 12.5 -3.5 -0.8 -0.0 -1.1 3.2 3.5 2.7 2.8
Respiratory disease 0.7 1.6 6.1 1.9 -2.5 0.1 1.2 -0.2 1.1 -0.1 0.7
Type 2 Diabetes (T2D) (2018) 1.3 2.5 7.3 -1.5 -1.2 0.8 0.2 1.7 2.7 1.1 2.0
Lung FEV1/FVC ratio 0.1 0.7 2.0 -1.3 0.5 -1.4 -0.9 0.1 0.5 0.1 0.7
Lung FVC 1.2 5.9 11.6 -1.7 -2.3 0.2 -0.5 3.0 3.3 2.7 3.4
Neuroticism 1.1 2.6 5.5 -2.3 -0.8 -0.3 -0.7 2.4 1.7 1.7 1.7
Chronotype (morning person) 0.3 0.8 1.4 -0.0 -1.1 1.0 1.2 0.9 0.4 1.0 0.6
Hair Pigment 0.0 0.7 1.7 -0.9 0.2 -0.9 -0.5 0.8 1.3 1.0 0.6
Tanning 0.0 0.6 2.5 -1.2 1.6 0.0 -0.5 0.3 0.6 0.1 0.3
Hand grip strength (left) 1.8 4.8 10.0 -2.0 -0.5 -0.9 -0.2 2.5 3.2 2.8 3.0
Number of treatments/medications taken 1.2 2.2 4.8 -1.8 -1.1 -1.1 -0.6 1.4 2.2 1.4 1.7
Average weekly spirits intake 0.2 0.2 0.8 -0.1 0.9 0.4 -0.1 -0.2 -0.7 -0.3 -0.4
Sensitivity / hurt feelings 0.1 0.2 0.7 -0.4 -0.2 -0.4 -0.3 -0.4 -0.2 -0.8 -0.2
Frequency of depressed mood in last 2 weeks 2.3 3.3 7.2 -0.7 -2.2 1.7 1.0 2.7 1.5 2.0 1.9
Hearing difficulty/problems: Yes 0.5 0.7 2.6 0.8 -0.6 1.3 1.6 -0.0 -0.8 0.4 -0.0
Relative age of first facial hair 0.6 1.2 2.5 0.7 -1.4 -1.6 -1.1 0.6 1.5 0.4 0.9
Other serious medical condition/disability diagnosed by doctor 0.2 0.2 0.9 0.1 -0.2 -1.0 0.0 -0.0 -0.5 0.7 0.1
Ever used hormone-replacement therapy (HRT) 0.3 0.3 1.2 0.5 -1.1 -0.4 -0.5 0.4 0.7 0.2 0.1
Ever had hysterectomy (womb removed) 2.0 2.2 5.2 1.2 0.7 -0.1 -0.3 -1.6 -1.9 -2.1 -2.3
Systolic blood pressure, automated reading 0.4 1.1 2.1 0.5 1.1 -0.9 -0.4 -1.3 -1.4 -1.1 -1.1
Eye problems/disorders: Diabetes related eye disease 0.3 0.4 1.2 1.1 0.6 0.4 1.0 0.0 0.0 0.2 -0.0
Angina 0.4 0.5 1.4 -0.6 -1.2 0.0 0.7 0.5 1.1 0.4 0.5
Medication for hormone replacement therapy 0.7 0.8 1.9 -1.4 -0.4 -0.2 -0.7 1.3 1.0 1.0 0.6
Vitamin and mineral supplements 0.8 1.1 2.9 0.5 1.2 -0.1 -0.4 -1.7 -1.5 -1.1 -0.9
Supplements: Zinc 0.8 0.9 2.3 0.9 0.1 1.5 1.3 0.1 -1.2 -0.2 -0.7
Medication: Co-codamol 1.3 1.6 3.3 1.0 1.8 -1.6 -1.0 -1.5 -1.1 -0.9 -0.5
Medication: Metformin 1.7 2.4 7.0 -1.9 -0.2 -0.2 -0.5 1.7 2.6 1.3 1.9
Diabetes (father) 0.2 0.2 0.8 -0.2 -0.2 -0.8 -0.9 0.5 0.1 0.2 -0.2
Diabetes (mother) 0.8 1.0 2.1 -1.0 1.4 -0.8 -1.0 -1.0 -0.6 -1.0 -1.0
Severe depression (siblings) 1.1 1.2 4.0 0.3 -2.0 1.4 1.7 0.2 0.5 0.3 0.5
Pack years adult smoking proportion 0.1 0.2 0.6 0.8 -0.3 -0.5 0.2 0.2 0.1 -0.3 -0.4
Impedance of leg (right) 0.1 0.3 1.2 -0.3 -0.9 1.1 -0.0 0.6 0.4 -0.0 0.2
Leg fat-free mass (left) 0.2 1.2 2.5 0.8 1.6 -1.3 0.4 -1.3 -1.4 -0.6 -0.8
Trunk fat percentage 0.4 1.5 4.0 0.6 0.0 0.5 0.6 -1.4 -2.0 -1.5 -1.8
Hand grip strength (right) 2.4 6.6 16.7 -1.3 -1.1 -0.1 0.6 2.7 3.9 3.3 4.1
Townsend deprivation index at recruitment 0.3 0.4 1.2 -0.2 -1.1 0.8 1.0 -0.1 0.1 0.1 0.5
Current tobacco smoking 0.2 0.3 1.0 0.1 -1.0 -0.2 -0.4 0.0 -0.2 -0.6 -0.7
Average weekly fortified wine intake 1.4 1.7 4.4 -0.2 2.1 -1.0 -1.1 -1.0 -1.6 -1.0 -1.4
Maternal smoking around birth 0.2 0.3 0.8 0.4 -0.5 0.6 0.9 0.4 -0.5 0.1 -0.3
Fed-up feelings 2.0 3.6 10.2 -3.2 -0.2 -0.3 -0.1 2.2 2.6 1.8 2.1
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.3 0.9 0.2 -0.4 1.0 0.8 0.2 -0.9 0.3 0.1
Relative age voice broke 0.7 1.0 2.4 0.6 -1.2 -1.0 -1.4 1.0 1.5 0.2 0.2
Taking other prescription medications 1.6 2.4 5.1 -2.1 -0.9 -0.3 -0.3 1.6 2.3 1.6 1.9
Age when periods started (menarche) 0.4 1.1 2.4 -0.7 -0.2 -0.7 0.6 0.8 1.3 1.5 1.5
Bilateral oophorectomy (both ovaries removed) 1.9 2.2 6.3 0.7 -1.1 2.5 1.9 1.8 0.1 1.6 0.5
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.1 3.6 -1.2 0.3 0.1 -0.0 1.3 1.9 0.9 0.8
Tinnitus: Yes, but not now, but have in the past 1.0 1.1 2.1 1.0 0.7 -1.2 -1.5 -0.6 -0.7 -1.1 -1.3
Qualifications: CSEs or equivalent 1.0 1.3 3.2 -1.1 -0.3 -0.3 0.0 1.3 1.3 1.8 1.5
Serious illness, injury or assault to yourself 1.4 1.7 4.7 -1.1 -0.1 -0.9 0.4 1.3 1.3 1.9 2.2
High blood pressure 0.1 0.2 0.7 -0.9 0.6 -0.2 -0.5 0.0 -0.4 -0.1 -0.5
Hayfever, allergic rhinitis or eczema 0.1 0.3 0.7 -0.6 0.4 -0.4 -0.9 -0.3 0.6 -0.5 -0.3
Multivitamins +/- minerals 0.9 1.1 2.9 -0.8 -0.3 -0.8 -0.3 1.7 1.0 1.6 1.1
Stomach or abdominal pain in last month 1.8 2.3 3.7 -1.9 -1.5 0.3 0.5 1.9 1.7 1.8 1.5
Supplements: Glucosamine 0.4 0.6 1.9 0.3 0.3 -1.4 -0.8 -0.4 0.8 -0.9 -0.3
Diverticular disease/diverticulitis (self-reported) 3.2 3.8 10.0 -0.9 -0.4 -0.1 1.3 2.4 2.2 3.2 2.7
Medication: Atenolol 0.9 1.1 2.0 0.2 1.1 -1.4 -0.9 -0.9 -1.1 -1.1 -1.3
Medication: Levothyroxine sodium 3.9 6.7 14.9 -2.6 -1.5 -0.9 -0.3 2.9 3.9 2.9 3.4
Sitting height 0.2 1.1 4.5 -0.5 2.1 -1.7 -1.1 -0.4 -0.2 -0.1 -0.2
Chronic bronchitis/emphysema (father) 0.6 0.7 1.4 0.8 -1.2 1.1 1.2 -0.0 -0.1 0.3 0.8
High blood pressure (mother) 1.4 2.0 3.9 -2.0 1.1 -1.3 -1.9 0.9 1.6 1.1 1.0
Body mass index (BMI) 0.2 0.9 2.2 0.3 0.6 -0.3 -0.0 -1.1 -1.5 -0.9 -1.4
Impedance of leg (left) 0.2 0.8 1.7 -1.0 -1.2 0.9 -0.2 1.3 1.1 0.4 0.6
Leg predicted mass (left) 0.2 1.2 2.3 0.8 1.5 -1.2 0.5 -1.3 -1.4 -0.6 -0.8
Trunk fat mass 0.3 1.4 3.8 0.6 0.5 -0.0 0.5 -1.5 -1.9 -1.3 -1.6
Waist circumference 0.4 1.4 4.0 0.6 0.7 0.1 0.4 -1.2 -2.0 -1.3 -1.8
Number of incorrect matches in round 2.1 3.6 8.5 -0.7 -2.2 2.9 2.3 2.1 0.7 1.7 1.3
Past tobacco smoking 1.6 2.9 6.2 0.7 0.9 -1.3 -0.3 -2.2 -2.5 -2.0 -2.2
Alcohol usually taken with meals 2.0 3.3 5.9 -1.0 -1.9 2.0 2.4 1.4 1.5 2.0 1.8
Nervous feelings 1.4 2.6 4.5 -1.5 -1.3 1.6 1.4 2.1 1.7 1.5 1.6
Frequency of tenseness / restlessness in last 2 weeks 1.0 1.5 5.0 0.5 -1.7 2.2 1.5 1.1 -0.1 0.6 -0.0
Hearing difficulty/problems with background noise 0.5 0.8 3.2 0.2 -0.5 1.8 1.5 0.6 -0.2 0.5 0.2
Hair/balding pattern: Pattern 2 0.4 0.5 1.2 -0.8 0.5 -0.4 0.3 -0.2 -0.7 1.1 0.9
Had menopause 0.2 0.2 0.6 0.6 -0.6 0.8 0.1 0.4 -0.1 -0.0 0.1
Had other major operations 1.1 1.4 3.6 1.9 -0.6 1.3 1.7 -0.6 -1.2 -0.8 -0.2
Forced vital capacity (FVC) 0.5 2.0 5.7 -0.4 -0.8 0.3 1.1 1.6 1.3 2.0 2.4
Heel bone mineral density (BMD) T-score, automated (right) 0.4 0.9 2.4 -0.7 -0.3 1.1 0.6 1.5 1.6 0.6 0.4
Ever unenthusiastic/disinterested for a whole week 0.8 0.9 2.4 0.3 -0.2 -0.4 -0.8 -1.1 -0.9 -1.5 -1.5
Qualifications: None of the above 0.4 0.8 3.5 -1.9 0.7 -0.9 -0.7 0.4 0.4 -0.3 -0.8
Financial difficulties in last 2 years 1.2 1.6 4.6 1.8 -0.6 0.4 0.0 -0.6 -1.2 -1.5 -2.1
Mouth/teeth dental problems 0.1 0.2 0.8 -0.7 0.9 -0.2 -0.3 -0.1 -0.1 -0.3 -0.5
Heart attack 0.9 1.2 3.1 -0.6 -1.1 1.8 1.4 0.8 1.0 0.6 0.8
Allergy 0.1 0.2 0.6 0.1 0.8 -0.1 -0.4 0.1 -0.6 0.0 -0.3
Pain all over the body in last month 1.0 1.1 3.4 0.0 -1.3 1.8 0.9 1.0 0.7 0.7 0.7
Diabetes (self-reported) 0.8 1.2 3.1 -1.4 0.0 0.2 0.3 1.2 1.4 1.1 1.8
Hayfever/allergic rhinitis (self-reported) 0.7 1.0 2.4 0.5 1.4 -0.4 -0.0 -1.1 -1.6 -0.9 -1.1
Medication: Ramipril 1.1 1.4 3.9 -1.4 -1.5 0.4 0.2 0.9 2.0 0.6 1.2
Medication: Simvastatin 0.6 0.9 3.2 -1.2 1.8 -0.7 -0.9 -0.5 -0.8 -0.0 -0.5
Fluid intelligence score 0.6 1.2 2.4 0.6 1.4 -0.1 -0.4 -1.6 -1.5 -1.3 -0.9
Illnesses of siblings 1.3 1.8 2.6 1.6 -1.4 1.1 1.6 1.3 0.8 1.5 1.3
Neuroticism score 0.9 1.9 5.2 -2.3 -0.3 -0.8 -0.7 1.7 1.7 1.2 1.2
Weight 0.3 1.5 3.2 0.6 1.4 -0.9 -0.0 -1.5 -1.8 -1.1 -1.5
Impedance of arm (right) 0.1 0.6 2.0 0.3 -1.4 1.4 0.7 0.3 -0.1 -0.3 0.1
Arm fat percentage (right) 0.3 1.3 3.6 0.3 0.5 -0.1 -0.0 -1.3 -1.9 -1.3 -1.8
Trunk fat-free mass 0.2 1.1 4.0 0.1 2.0 -1.9 -0.3 -0.9 -0.6 0.0 -0.1
Hip circumference 0.3 1.2 2.2 0.4 1.0 -1.1 -0.4 -1.5 -1.5 -1.1 -1.2
Time employed in main current job 1.4 1.6 3.8 1.8 1.2 1.0 0.7 -0.8 -1.9 -1.1 -1.2
Alcohol intake versus 10 years previously 0.1 0.2 0.6 0.5 -0.2 -0.6 -0.8 0.0 0.1 -0.4 -0.4
Father’s age at death 0.3 0.5 1.9 -0.4 0.2 -1.1 -1.4 0.2 -0.4 0.5 0.0
Worrier / anxious feelings 0.9 1.7 3.0 -1.7 -1.1 -0.3 0.4 1.5 1.6 1.5 1.4
Frequency of tiredness / lethargy in last 2 weeks 1.4 2.3 7.3 -2.7 -0.4 -0.4 -0.9 1.7 1.7 1.6 1.2
Falls in the last year 0.7 0.9 2.9 -1.1 0.9 -1.7 -1.4 0.4 0.1 0.6 0.2
Hair/balding pattern: Pattern 3 2.6 3.9 7.1 1.8 1.6 -0.9 -1.0 -2.4 -2.7 -2.4 -2.3
Number of live births 1.7 2.4 5.3 -2.1 -1.0 0.1 -1.4 2.1 2.3 1.0 1.0
Forced expiratory volume in 1-second (FEV1) 0.7 2.4 6.5 -1.4 -0.3 -0.5 0.3 1.7 1.7 2.1 2.5
Pulse rate 0.9 1.4 3.3 1.8 -0.9 0.8 1.5 -1.2 -1.3 -1.1 -0.4
Happiness 0.6 0.7 2.8 -1.2 -0.5 0.2 -0.7 0.7 1.7 0.1 0.5
Noisy workplace 0.2 0.2 0.8 -0.0 0.1 -0.0 -0.9 0.3 -0.0 -0.2 -0.8
Qualifications: A levels/AS levels or equivalent 0.3 0.7 3.8 -0.5 2.0 0.2 -0.4 -0.8 -0.2 -0.5 -0.0
Serious illness, injury or assault of a close relative in last 2 years 2.3 2.6 4.0 -0.6 -1.3 2.0 1.8 1.6 1.3 1.9 1.9
Mouth/teeth dental problems: Dentures 0.2 0.4 1.6 -0.2 -0.4 -0.8 -1.3 0.4 0.5 -0.4 -0.2
Asthma 0.5 1.1 3.7 0.8 -1.9 0.6 1.1 0.4 1.1 0.6 1.0
Medication: Ibuprofen (e.g. Nurofen) 4.4 5.5 11.9 1.0 -3.4 2.2 3.3 1.9 1.9 1.8 2.2
Medication: Cholesterol lowering 0.8 1.3 3.8 -2.0 -0.1 -0.6 -1.1 1.2 1.7 0.6 0.5
Depression (self-reported) 0.7 0.8 1.7 -1.2 -0.4 -1.3 -1.0 0.8 0.9 0.7 0.4
Medication: Lansoprazole 1.2 1.4 3.5 -1.6 1.1 -1.9 -1.2 0.1 0.7 0.5 1.1
Prospective memory result 1.5 1.9 5.0 0.9 -0.7 1.2 1.7 1.3 0.1 2.2 1.7
Lung cancer (father) 0.7 0.8 2.6 -0.8 1.6 1.2 0.6 0.0 -1.1 0.1 -0.4
Illnesses of mother 1.4 1.7 5.0 1.2 -2.0 2.2 1.6 -0.4 -0.5 -0.6 -0.2
Forced expiratory volume in 1-second (FEV1), Best measure 1.1 3.5 8.6 -1.7 -0.4 -0.4 0.7 2.2 2.0 2.6 2.9
Pulse wave Arterial Stiffness index 2.0 2.3 4.5 0.8 2.1 -0.3 -0.9 -2.0 -1.6 -1.8 -1.5
Impedance of arm (left) 0.2 0.7 3.2 0.4 -0.9 1.8 0.7 -0.2 -0.5 -0.9 -0.4
Arm fat mass (right) 0.3 1.1 2.9 0.2 0.8 -0.5 0.1 -1.3 -1.7 -1.0 -1.5
Trunk predicted mass 0.2 1.2 4.2 0.0 2.1 -2.0 -0.4 -0.9 -0.6 0.0 -0.1
Standing height 0.1 1.1 4.2 0.6 2.1 -1.2 -0.0 -1.1 -1.0 -0.5 -0.3
Length of working week for main job 0.9 1.0 3.5 1.9 0.7 -0.9 -0.5 -1.3 -0.7 -0.7 -0.4
Exposure to tobacco smoke at home 0.5 0.5 2.0 1.4 -0.9 -1.0 -0.0 0.2 0.4 0.2 0.4
Breastfed as a baby 0.4 0.5 1.1 0.9 0.9 -0.3 -0.5 -0.8 -1.1 -0.5 -0.3
Tense / ‘highly strung’ 0.9 1.5 3.5 -1.3 0.1 0.8 0.7 1.9 1.0 1.6 1.2
Seen doctor (GP) for nerves, anxiety, tension or depression 1.5 2.4 4.7 -2.2 -1.0 0.2 0.0 2.0 1.8 1.8 1.6
Hair/balding pattern: Pattern 4 0.2 0.5 2.1 -0.5 0.2 -1.5 -0.8 -0.4 0.4 -0.2 -0.4
Birth weight of first child 0.1 0.2 0.7 0.6 0.3 -0.1 0.6 -0.8 -0.3 -0.4 0.2
Peak expiratory flow (PEF) 0.2 0.4 0.8 -0.9 0.2 -0.6 -0.8 0.6 0.5 0.3 0.6
Pulse wave reflection index 0.8 1.0 3.8 -0.8 1.9 -0.6 -1.5 -0.8 -0.5 -0.4 -0.6
Ever highly irritable/argumentative for 2 days 0.4 0.5 2.2 -0.1 0.2 -0.8 -1.5 0.6 0.2 -0.3 -0.8
Loud music exposure frequency 0.8 0.8 1.7 0.3 -1.3 0.1 1.1 0.9 0.4 1.1 1.1
Qualifications: O levels/GCSEs or equivalent 0.1 0.2 0.8 -0.0 0.9 -0.7 0.1 -0.4 0.4 -0.1 0.3
Mouth/teeth dental problems: Bleeding gums 0.9 1.1 2.6 1.6 -1.6 1.4 1.2 0.0 -0.2 0.6 0.3
Blood clot in the leg (DVT) 2.9 3.7 8.3 -0.4 -2.2 0.4 1.5 1.9 2.1 2.4 2.9
Medication: Paracetamol 0.6 1.0 6.5 -2.5 0.4 0.2 -0.5 0.8 0.4 0.3 0.2
Headache pain in last month 2.9 5.1 10.2 -3.2 -1.1 0.3 0.3 2.8 2.5 2.8 2.7
Medication for cholesterol, blood pressure or diabetes 0.6 1.0 3.1 1.4 -0.6 1.3 1.8 0.0 -0.9 0.5 0.5
Glaucoma (self-reported) 1.2 1.4 2.5 -1.6 -0.0 1.5 0.8 1.6 0.5 1.3 1.1
Gout (self-reported) 0.6 0.8 1.7 -0.2 1.3 -0.6 -1.0 1.2 0.6 1.1 0.7
Hypothyroidism/myxoedema (self-reported) 4.0 7.9 18.2 -2.7 -1.8 -1.0 -0.7 3.2 4.3 3.1 3.6
Medication: Amlodipine 0.2 0.2 0.8 0.9 -0.7 -0.2 0.2 -0.2 -0.5 -0.4 -0.3
Medication: Ventolin 100micrograms inhaler 1.5 1.9 6.1 0.9 -2.5 0.7 1.4 0.5 1.7 0.7 1.6
Birth weight 0.1 0.1 0.4 -0.4 0.6 -0.1 0.1 0.1 -0.6 0.5 0.1
Chronic bronchitis/emphysema (mother) 0.9 1.0 2.4 1.1 0.4 -1.0 -0.7 -1.6 -0.9 -1.2 -0.7
High blood pressure (siblings) 1.1 1.6 3.3 -0.7 1.5 -1.2 -1.8 -1.2 -0.8 -1.3 -1.3
Forced vital capacity (FVC), Best measure 0.8 2.8 6.6 -1.4 -0.4 0.4 1.1 2.0 1.6 2.4 2.6
Body fat percentage 0.3 1.3 3.4 0.4 0.1 0.3 0.4 -1.3 -1.9 -1.4 -1.8
Leg fat percentage (right) 0.3 0.9 2.9 0.0 0.3 0.2 0.2 -1.0 -1.7 -1.1 -1.5
Arm fat-free mass (right) 0.3 1.5 4.6 0.5 2.1 -1.8 -0.2 -1.4 -1.0 -0.6 -0.7
Exposure to tobacco smoke outside home 1.5 1.9 4.0 1.1 0.5 0.4 -0.6 -1.7 -1.9 -1.8 -2.0
Comparative body size at age 10 0.3 0.9 3.4 -0.1 -0.5 -0.4 0.4 0.1 1.5 0.7 1.8
Number of full brothers 1.6 2.0 4.4 -2.1 0.1 -2.1 -2.1 0.6 1.2 0.6 0.7
Worry too long after embarrassment 0.4 0.7 1.9 -1.3 0.5 -1.4 -1.0 -0.5 0.1 -0.2 -0.2
Seen a psychiatrist for nerves, anxiety, tension or depression 1.6 2.1 4.1 -1.1 -1.5 0.5 0.8 1.6 1.6 2.0 1.8
Wheeze or whistling in the chest in last year 1.4 2.5 8.6 1.4 -2.9 1.7 2.3 0.7 0.1 0.6 0.1
Number of children fathered 0.8 0.9 2.7 -0.0 -1.5 1.6 0.9 1.0 0.4 0.7 0.1
Reason for reducing amount of alcohol drunk: Health precaution 1.0 1.1 1.8 -0.4 -1.1 1.0 1.3 0.8 1.1 1.2 1.2
Age at first live birth 1.3 2.3 5.9 1.1 0.9 0.3 -0.4 -1.9 -1.4 -2.1 -2.4
Pulse wave peak to peak time 1.9 2.2 4.1 -0.6 -2.0 0.3 1.0 2.0 1.6 1.8 1.5
Health satisfaction 0.3 0.4 1.1 -0.9 0.0 0.1 -0.6 1.0 0.5 0.3 -0.4
Shortness of breath walking on level ground 0.8 1.0 2.0 1.2 -0.7 1.4 1.4 1.1 0.0 0.9 0.4
Qualifications: College or University degree 0.7 2.2 8.6 2.9 -0.2 0.6 0.8 -2.0 -1.1 -1.4 -1.0
Eye problems/disorders: None of the above 0.6 0.7 3.0 -0.5 0.8 -1.7 -1.4 0.2 0.3 0.0 0.1
Mouth/teeth dental problems: Loose teeth 1.7 2.1 4.3 -1.4 -1.2 -0.4 -0.8 1.9 2.1 1.3 1.5
Emphysema/chronic bronchitis 0.2 0.2 0.4 0.5 -0.7 -0.0 0.7 -0.0 -0.3 -0.2 -0.4
Medication for pain relief, constipation, heartburn 1.0 1.8 5.3 2.3 0.6 0.3 -0.1 -1.3 -1.7 -1.1 -1.6
Neck or shoulder pain in last month 0.8 1.2 3.6 -1.5 -0.9 1.9 1.0 1.2 0.1 0.6 -0.2
Medication: Blood pressure 0.7 1.3 2.3 -0.1 0.8 -1.5 -1.5 -1.1 0.0 -1.5 -1.3
Angina (self-reported) 0.6 0.8 1.7 -1.2 -0.9 0.2 0.6 0.9 1.3 0.7 0.8
Migraine (self-reported) 0.3 0.4 1.1 -0.4 -1.1 0.5 1.0 0.1 0.5 0.0 0.4
Medication: Ibuprofen 1.9 2.2 6.5 0.4 -2.6 1.1 1.8 1.3 1.0 1.3 1.5
Medication: Allopurinol 0.2 0.2 0.8 0.7 0.0 0.4 0.1 0.9 -0.2 0.4 -0.5
Medication: Omeprazole 0.5 0.7 1.6 -1.1 -1.2 1.2 0.8 0.2 -0.6 -0.2 -0.2
Medication: Seretide 50 evohaler 1.3 1.5 3.6 1.9 -1.7 1.7 1.4 0.4 0.1 0.5 0.3
Mean time to correctly identify matches 0.9 1.7 4.6 -0.4 -2.1 -0.2 0.3 1.6 1.8 1.2 1.0
Heart disease (mother) 2.7 3.3 5.5 -0.6 -1.5 2.1 1.9 2.3 2.0 1.8 1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.8 1.0 2.1 -0.9 -0.7 0.0 -0.9 1.2 1.1 1.0 1.4
Whole body fat mass 0.4 1.5 3.8 0.5 0.8 -0.3 0.3 -1.6 -1.9 -1.3 -1.7
Leg fat mass (right) 0.3 1.1 2.7 0.3 0.7 -0.4 0.2 -1.2 -1.6 -1.1 -1.6
Arm predicted mass (right) 0.3 1.6 4.5 0.6 2.1 -1.7 -0.1 -1.5 -1.2 -0.8 -0.9
Pulse rate, automated reading 0.5 1.5 3.5 1.7 -1.0 1.0 1.9 -1.2 -1.1 -0.7 -0.2
Alcohol intake frequency. 1.2 2.7 4.9 -1.8 -1.2 -0.8 -0.2 1.9 1.9 2.2 2.2
Comparative height size at age 10 0.4 2.2 4.9 2.2 1.1 -0.9 0.2 -2.0 -1.7 -1.6 -1.1
Number of full sisters 0.2 0.3 1.0 -0.2 -1.0 -0.2 -0.7 -0.2 0.3 -0.5 -0.5
Suffer from ‘nerves’ 0.2 0.3 0.5 -0.7 -0.3 -0.6 -0.5 0.7 0.7 0.4 0.7
Overall health rating 0.6 1.2 2.1 -1.2 -1.3 0.7 1.0 1.2 0.7 1.5 1.1
Chest pain or discomfort 0.3 0.5 2.2 0.6 -1.5 0.1 1.0 0.1 0.1 -0.2 -0.1
Had major operations 0.9 1.0 2.5 1.1 -1.2 1.5 1.6 0.6 -0.4 0.3 -0.0
Age at last live birth 2.5 3.6 8.1 1.7 0.7 -0.3 -0.7 -2.5 -1.9 -2.7 -2.9
Family relationship satisfaction 0.6 0.7 3.0 1.0 -1.7 0.7 1.0 -0.2 0.3 -0.2 0.3
Leg pain on walking 0.3 0.3 1.3 -0.0 -0.4 -1.1 -0.9 0.4 -0.2 0.3 -0.1
Qualifications: NVQ or HND or HNC or equivalent 0.6 0.7 1.8 -0.6 -0.6 0.0 -0.3 0.8 1.2 1.0 1.4
Commuting to job workplace: Car/motor vehicle 0.6 0.6 1.7 0.9 -0.2 1.3 0.8 0.1 -0.8 -0.5 -1.0
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 1.3 1.1 0.5 -0.9 -0.4 -1.1 -0.7 -0.6 -0.3
Medication: Aspirin 0.5 0.6 1.7 -0.8 0.8 -1.3 -0.9 -0.7 0.6 -0.5 -0.0
Supplements: Vitamin C 0.7 0.8 2.0 1.4 -0.9 0.5 0.7 -0.5 -0.4 -1.2 -1.1
Knee pain experienced in last month 0.3 0.5 1.2 -0.6 -1.1 0.8 0.5 0.5 -0.3 0.8 0.6
Hypertension (Self-reported) 0.2 0.4 1.1 -1.1 0.9 -0.4 -0.9 -0.0 -0.3 -0.3 -0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.1 1.2 4.8 -0.6 1.0 -1.6 -2.2 -0.7 -0.3 -0.8 -0.2
Illnesses of father: Heart disease 0.7 1.0 2.4 -1.6 -0.5 0.4 0.9 1.0 1.2 0.8 0.9
Illnesses of siblings: Diabetes 0.2 0.3 1.3 0.1 0.3 -1.1 -0.8 -0.2 -0.0 -0.3 0.2
Smoking status: Previous 2.4 3.6 7.4 -0.6 -0.9 1.1 0.6 2.4 2.7 2.4 2.6
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.3 0.9 -0.3 -0.3 -0.1 0.6 0.8 0.6 0.9 0.7
Whole body fat-free mass 0.2 1.1 3.3 0.4 1.8 -1.7 -0.0 -1.1 -1.0 -0.3 -0.5
Leg fat-free mass (right) 0.2 1.0 2.3 0.6 1.5 -1.5 0.2 -1.1 -1.1 -0.4 -0.7
Arm fat percentage (left) 0.4 1.8 4.2 0.3 0.8 -0.2 -0.2 -1.6 -2.0 -1.6 -2.0
Average weekly red wine intake 0.1 0.1 0.3 -0.2 -0.2 0.5 0.1 0.1 0.5 0.0 -0.2
Handedness (chirality/laterality): Left-handed 1.3 1.6 3.2 0.2 -1.4 0.7 1.8 1.3 1.1 1.4 1.6
Mood swings 0.7 1.3 4.4 -0.6 -2.1 0.2 0.0 1.5 1.5 0.8 0.6
Loneliness, isolation 2.0 2.8 6.3 -1.5 2.5 -2.4 -2.3 -0.9 -0.6 -1.0 -0.7
Long-standing illness, disability or infirmity 3.0 4.6 7.5 -1.9 -2.2 -0.2 0.8 2.6 2.6 2.5 2.7
Ever had bowel cancer screening 0.1 0.1 0.6 0.3 -0.5 -0.3 0.2 -0.0 -0.7 0.2 0.1
Diabetes diagnosed by doctor 0.8 1.3 3.6 -0.9 -0.6 0.1 -0.1 1.4 1.9 1.0 1.7
Ever had stillbirth, spontaneous miscarriage or termination 0.9 1.0 1.7 0.8 0.4 -1.0 -1.1 -1.3 -0.6 -1.3 -1.2
Friendships satisfaction 0.2 0.2 0.4 -0.3 0.2 -0.1 -0.6 -0.5 -0.1 -0.6 -0.5
Qualifications: nursing, teaching 1.3 2.1 5.1 2.3 0.0 0.5 1.0 -1.5 -1.6 -1.6 -1.7
Commuting to job workplace: Walk 0.5 0.6 1.3 0.0 0.4 1.1 0.2 -1.2 -1.1 -0.7 -0.4
Eye problems/disorders: Cataract 0.3 0.4 1.0 0.2 0.3 1.0 0.3 -0.7 -0.8 -0.4 -0.6
Mouth/teeth dental problems: Mouth ulcers 0.3 0.4 1.7 0.1 1.3 -0.9 -0.4 0.0 -0.3 0.6 0.2
Medication for cholesterol 0.5 0.8 2.3 1.5 -0.9 0.5 1.5 -0.1 0.4 -0.1 0.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.9 1.0 2.0 -1.1 -0.6 -1.0 -0.6 1.1 1.4 1.1 1.0
Back pain experienced in last month 1.0 1.4 2.7 -1.6 -0.6 -0.6 -1.0 1.5 1.6 0.9 1.1
Mineral and other dietary supplements 0.6 0.8 3.1 0.6 0.8 0.7 -0.1 -0.8 -1.7 -0.4 -1.0
Breast cancer (self-reported) 1.5 1.8 5.6 0.8 -1.2 2.4 2.1 -0.2 -1.3 -0.2 -0.6
Asthma (self-reported) 0.5 1.1 4.0 0.7 -2.0 0.5 0.9 0.5 1.2 0.6 1.0
Osteoporosis (self-reported) 0.9 1.1 3.3 -0.7 1.3 -1.4 -1.8 -0.4 -0.3 -0.7 -0.8
Osteoarthritis (self-reported) 2.2 2.9 4.6 -1.3 -1.9 2.1 1.6 2.1 0.9 1.8 1.5
Medication: Aspirin 0.2 0.3 0.8 -0.3 0.4 -0.8 -0.4 -0.9 0.4 -0.6 0.0
Medication: Gliclazide 0.7 0.8 2.0 1.1 -1.4 -0.7 -0.4 -0.1 1.2 -0.2 0.8
Illnesses of father: None of the above (group 1) 0.8 1.0 2.0 1.4 0.1 -0.3 -0.0 -1.4 -1.1 -1.3 -1.3
Smoking status: Current 0.2 0.3 0.6 0.1 -0.6 -0.3 -0.7 -0.1 -0.1 -0.7 -0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.9 2.0 4.5 -1.3 -1.3 -0.7 0.1 1.5 1.6 1.7 2.1
Whole body water mass 0.2 1.3 3.8 0.5 1.9 -1.7 -0.0 -1.2 -1.1 -0.4 -0.6
Leg predicted mass (right) 0.2 0.9 2.3 0.5 1.5 -1.4 0.3 -1.1 -1.1 -0.4 -0.6
Arm fat mass (left) 0.4 1.8 4.0 0.5 1.3 -0.7 -0.1 -1.6 -2.0 -1.4 -1.8
Number of self-reported non-cancer illnesses 0.5 0.9 4.0 -1.0 0.5 -2.0 -1.0 -0.2 0.3 0.6 0.7
Average weekly champagne plus white wine intake 0.1 0.2 0.6 0.6 -0.3 -0.4 0.8 -0.0 0.1 0.2 0.4
Miserableness 0.3 0.5 1.8 -1.4 -0.9 0.2 0.3 1.1 0.1 0.4 -0.0
Guilty feelings 0.1 0.1 0.3 0.4 -0.5 -0.1 -0.3 0.1 -0.6 0.1 0.1
Wears glasses or contact lenses 1.3 1.5 3.1 -0.1 1.8 -1.6 -1.1 -1.3 -1.2 -0.9 -0.8
Ever taken oral contraceptive pill 1.1 1.3 2.8 1.3 0.4 -0.2 -0.9 -1.3 -0.8 -1.7 -1.5
Hearing aid user 0.2 0.2 1.0 -0.0 1.0 -0.6 0.5 -0.4 -0.3 -0.2 -0.1
Mother’s age at death 0.9 1.1 2.1 -1.0 -1.1 1.3 -0.1 1.2 0.7 1.4 1.0
Financial situation satisfaction 0.3 0.4 1.2 -1.1 -0.3 0.7 0.1 0.7 0.9 0.3 -0.2
Tinnitus: Yes, now most or all of the time 0.7 0.8 2.7 -1.6 0.3 0.4 0.2 1.1 0.6 1.1 1.0
Commuting to job workplace: Public transport 0.2 0.2 0.6 -0.4 0.8 -0.3 -0.5 -0.2 -0.4 -0.3 -0.1
Eye problems/disorders: Glaucoma 1.1 1.3 2.6 -1.2 0.0 1.6 1.4 1.2 0.4 1.3 1.3
Medication: Blood pressure 0.4 0.7 1.5 -0.4 1.2 -0.4 -0.9 -0.7 -1.2 -0.5 -0.8
Pain type(s) experienced in last month: Hip pain 3.3 4.1 7.1 -2.0 -1.4 2.4 2.0 2.7 1.5 2.3 1.7
Supplements: Fish oil (including cod liver oil) 2.7 3.6 6.0 -1.4 -1.8 0.5 1.0 2.4 2.4 2.3 2.3
High cholesterol (Self-reported) 0.5 0.9 2.8 -1.7 1.2 -0.7 -1.4 0.6 0.0 0.3 -0.3
Medication: Bendroflumethiazide 0.5 0.8 2.3 -0.3 0.9 -0.1 -0.6 -0.7 -1.3 -0.9 -1.5
Medication: Paracetamol 0.5 0.8 5.7 -2.4 0.0 0.3 -0.5 0.5 0.0 -0.1 -0.1
Medication: Lisinopril 0.6 0.7 1.7 0.2 -0.3 -0.3 -1.2 -1.1 0.0 -1.3 -1.2
Medication: Atorvastatin 1.9 2.3 4.5 -2.0 -1.8 0.8 0.3 2.1 1.9 1.1 1.2
Illnesses of father: High blood pressure 0.6 0.7 2.6 -0.0 1.6 0.2 -0.6 -1.1 -0.9 -0.7 -0.8
Alcohol drinker status: Never 0.5 0.6 2.1 -1.4 0.0 0.3 -0.3 0.8 0.8 0.7 0.8
Ever smoked 0.8 1.4 4.4 -0.3 -0.9 0.4 -0.8 1.6 2.1 1.0 1.1
Basal metabolic rate 0.2 1.4 3.5 0.5 1.9 -1.7 -0.1 -1.3 -1.2 -0.5 -0.8
Leg fat percentage (left) 0.2 0.6 2.0 -0.2 0.1 0.0 0.2 -0.7 -1.4 -0.8 -1.2
Arm fat-free mass (left) 0.2 0.9 3.0 0.1 1.7 -1.7 -0.1 -0.8 -0.7 -0.1 -0.4
Number of operations (self-reported) 0.3 0.5 1.4 0.6 -0.4 1.2 1.2 0.4 -0.6 0.1 -0.2
Average weekly beer plus cider intake 0.4 0.5 1.6 1.3 -0.7 0.2 0.7 0.5 0.3 0.6 0.9
Irritability 0.5 0.8 2.6 -0.9 -0.6 -0.9 -0.6 0.7 1.6 0.3 0.9
Risk taking 1.5 2.2 4.0 1.3 0.5 -1.0 -0.9 -1.9 -1.3 -2.0 -2.0
Ever had prostate specific antigen (PSA) test 0.3 0.4 2.2 0.4 -1.5 -0.2 0.5 -0.4 0.3 -0.4 -0.2
Fractured/broken bones in last 5 years 0.1 0.1 0.4 0.0 0.0 -0.1 -0.0 -0.4 -0.6 -0.1 0.2
Age started oral contraceptive pill 1.3 1.7 5.6 2.4 -0.3 0.4 -0.2 -1.3 -1.2 -1.6 -1.4
Diastolic blood pressure, automated reading 0.2 0.5 1.5 -0.1 0.5 1.1 1.2 -0.3 -1.0 0.1 -0.1
Ever depressed for a whole week 1.4 1.7 3.7 -1.1 -1.9 -0.2 0.1 1.6 1.9 1.1 1.1
Unable to work because of sickness or disability 1.4 1.8 4.1 -0.7 -2.0 0.5 1.1 1.8 1.9 1.0 1.0
Commuting to job workplace: Cycle 2.6 3.1 11.3 -1.5 -0.5 -0.6 -0.2 1.6 3.4 1.7 2.3
Myopia 0.2 0.3 0.7 -0.4 0.8 -0.0 0.1 0.8 0.5 0.7 0.4
Vascular/heart problems diagnosed by doctor 0.1 0.2 0.7 0.8 -0.3 0.4 0.5 -0.2 0.2 -0.2 0.3
Cholesterol lowering medication 0.3 0.5 1.1 -0.8 1.0 0.8 0.2 -0.3 -1.1 0.1 -0.2
Medication: Omeprazole (e.g. Zanprol) 0.4 0.5 2.9 -1.7 -0.7 0.3 0.2 0.3 -0.2 0.0 0.1
Pain experienced in last month 2.8 4.7 8.3 2.4 1.5 -0.3 -0.0 -2.7 -2.4 -2.9 -2.9
Supplements: Calcium 0.3 0.4 1.0 0.9 0.4 -1.0 -0.5 -0.4 -0.2 -0.7 -0.0
Basal cell carcinoma (self-reported) 0.2 0.3 0.7 -0.2 -0.5 -0.7 0.0 -0.4 -0.1 -0.7 -0.8
Heart attack/myocardial infarction (self-reported) 0.6 0.8 2.3 -0.5 -1.0 1.5 1.2 0.5 0.8 0.3 0.5
Deep venous thrombosis (DVT) (self-reported) 2.7 3.5 7.6 -0.5 -2.1 0.4 1.4 1.9 2.1 2.3 2.7
Heart disease (siblings) 0.2 0.3 0.6 -0.7 -0.8 0.7 0.7 -0.1 -0.0 -0.4 -0.3
Alcohol drinker status: Previous 1.2 1.4 3.3 -0.0 -1.2 -0.4 0.6 1.0 1.6 1.5 1.8
Pack years of smoking 0.1 0.1 0.3 0.6 -0.2 -0.6 -0.1 0.0 0.1 -0.4 -0.5
Impedance of whole body 0.1 0.7 2.9 -0.2 -1.2 1.7 0.6 0.7 0.3 -0.1 0.2
Leg fat mass (left) 0.2 0.9 2.3 0.2 0.6 -0.4 0.3 -1.0 -1.5 -1.0 -1.5
Arm predicted mass (left) 0.2 1.1 3.3 0.2 1.8 -1.8 -0.1 -1.1 -0.8 -0.2 -0.4