Hub : Traits :

Qualifications: College or University degree

1547 significantly associated models · 348 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 40799427 42542658 2 1 1.2e-12 3.0e-11 3.8e-05 62 FOXO6
2 1 43042125 45378361 15 6 1.2e-17 2.9e-20 NaN NaN DMAP1 DPH2 HYI TIE1
3 1 45423943 46809419 1 1 2.8e-07 3.9e-06 2.6e-01 94 RP11-767N6.2
4 1 71163715 73435171 1 1 1.7e-23 2.1e-16 3.2e-01 98 NEGR1
5 1 73798439 75701824 5 1 2.1e-11 5.0e-10 2.5e-07 31 FPGT
6 1 92861307 94534354 6 1 7.6e-18 5.7e-18 1.0e+00 100 DR1
7 1 109135869 110742615 5 1 1.2e-09 5.5e-09 1.5e-08 6 SYPL2
8 1 150282784 151701345 1 1 5.7e-08 8.9e-05 2.0e-03 38 PRUNE
9 1 173437024 175663031 1 1 2.0e-07 2.1e-07 2.7e-01 96 RABGAP1L
10 1 183961643 185416670 1 1 1.2e-07 1.1e-07 1.0e+00 100 EDEM3
11 1 203692179 205241659 2 1 3.9e-09 1.6e-13 8.7e-06 64 MDM4
12 1 212274413 213679526 1 1 3.6e-07 1.4e-04 1.1e-01 82 TATDN3
13 1 234832199 236307360 1 1 8.6e-09 4.6e-09 1.0e+00 100 TBCE
14 1 242590540 244359621 3 1 3.2e-12 3.2e-12 1.0e+00 100 RP11-261C10.5
15 2 43899918 45698128 1 1 1.4e-09 1.5e-08 4.9e-03 75 CAMKMT
16 2 48072855 49519654 1 1 2.0e-07 8.2e-08 4.7e-03 72 STON1
17 2 72774203 74187703 2 1 2.7e-07 2.9e-07 1.3e-05 28 FBXO41
18 2 99468341 101731705 3 3 7.2e-16 1.1e-20 1.4e-02 93 AFF3 LONRF2
19 2 106725928 108199394 1 1 1.7e-07 3.4e-07 1.0e+00 100 ST6GAL2
20 2 161297929 162798581 2 1 2.9e-17 1.9e-16 1.0e+00 100 TANK
21 2 228038804 229427172 1 1 3.7e-08 2.7e-10 1.7e-05 54 TDGF1P2
22 2 233047291 234434621 1 1 5.6e-08 5.1e-07 1.5e-01 92 C2orf82
23 3 46730749 51377300 49 8 3.0e-40 4.6e-34 NaN NaN FAM212A GPX1 MON1A MST1R NAT6 PTPN23 QRICH1
24 3 61413773 62808969 1 1 1.0e-07 3.5e-08 4.2e-06 30 ID2B
25 3 107181540 108633112 1 1 5.3e-09 1.0e-08 2.5e-02 85 IFT57
26 4 1947324 3943984 7 1 7.2e-15 1.0e-13 2.9e-01 98 GRK4
27 4 17104059 18507692 1 1 2.6e-07 1.1e-07 1.5e-02 79 DCAF16
28 4 105598022 107092169 1 1 2.4e-13 1.6e-15 3.6e-06 66 PPA2
29 4 151637154 153373680 2 1 2.2e-09 2.8e-11 2.5e-06 50 FAM160A1
30 5 59028853 61156570 9 3 6.8e-19 5.5e-19 4.4e-03 90 ELOVL7 GNL3LP1 PART1
31 5 87006055 88677293 2 2 2.3e-10 7.6e-16 1.9e-04 79 CTC-498M16.2 LINC00461
32 5 92051598 93618113 1 1 8.4e-08 3.3e-08 1.6e-06 25 NR2F1-AS1
33 5 108341478 109898183 1 1 8.0e-09 3.0e-08 1.6e-01 94 MAN2A1
34 5 111615346 113515807 2 1 2.6e-08 2.8e-07 1.6e-01 93 DCP2
35 5 138933151 140378983 1 1 3.5e-07 7.8e-08 1.8e-02 81 PFDN1
36 5 176132977 177591495 3 1 4.8e-09 1.5e-08 6.3e-02 89 PRR7
37 6 25266147 26682323 1 1 1.2e-07 1.3e-17 6.6e-14 23 TRIM38
38 6 87358929 88997402 3 1 5.6e-09 1.5e-08 4.2e-02 87 RARS2
39 6 108183628 109704062 1 1 6.4e-10 1.3e-08 2.6e-01 96 FOXO3
40 6 110607412 112046324 1 1 3.4e-07 4.8e-08 1.4e-03 66 RPF2
41 7 1580921 2977732 1 1 2.3e-07 2.0e-12 3.2e-08 38 FTSJ2
42 7 20885792 22639717 1 1 1.3e-08 4.7e-10 2.5e-04 65 DNAH11
43 7 23913624 25432157 1 1 7.0e-08 2.5e-08 7.9e-02 90 MPP6
44 7 70546596 72313144 1 1 1.5e-10 1.9e-10 2.8e-01 97 CALN1
45 7 75059331 75842792 2 1 2.7e-07 2.3e-07 1.0e+00 100 TRIM73
46 7 99260092 100746658 3 1 9.4e-10 4.3e-06 7.4e-01 100 STAG3L5P-PVRIG2P-PILRB
47 7 126593467 128425768 1 1 3.9e-07 1.1e-08 2.0e-04 58 SND1
48 8 8716971 10335032 1 1 2.0e-07 6.5e-06 1.5e-02 71 TNKS
49 8 29996824 31433801 1 1 1.9e-08 1.8e-09 2.2e-02 86 TEX15
50 8 65740418 67170378 1 1 1.2e-07 1.3e-08 3.3e-02 86 CTD-3025N20.2
51 8 86841229 88271452 2 1 9.9e-11 4.0e-07 1.1e-04 42 CPNE3
52 8 109213088 110765282 1 1 2.2e-08 2.2e-06 4.4e-03 64 RP11-1084E5.1
53 8 140969818 142706843 1 1 4.0e-10 2.6e-12 6.1e-11 13 PTK2
54 8 142839492 144515639 6 2 7.3e-12 8.9e-09 6.9e-01 100 BAI1 PSCA
55 8 144975935 146293414 4 1 3.5e-08 7.4e-08 1.0e+00 100 CTD-2517M22.16
56 9 134778255 136238509 1 1 6.6e-10 4.0e-08 5.3e-07 16 DDX31
57 10 10349662 12076043 1 1 7.1e-11 1.3e-11 2.5e-04 71 CELF2
58 10 64195778 65911294 3 1 7.1e-11 3.4e-08 8.1e-04 63 JMJD1C-AS1
59 10 68946505 70924619 3 1 1.1e-11 2.2e-09 1.7e-02 84 DNA2
60 10 102853189 104956035 4 3 1.2e-12 4.5e-13 2.9e-01 98 ACTR1A HPS6 NPM3
61 10 111062431 112588355 1 1 1.8e-07 1.4e-07 1.0e+00 100 ADD3
62 10 125739009 127174440 1 1 7.6e-08 7.7e-08 9.4e-02 90 METTL10
63 10 133048749 134482926 2 2 2.1e-09 3.0e-13 1.7e-01 96 BNIP3 PPP2R2D
64 11 61697904 63110149 1 1 3.2e-07 3.2e-07 1.0e+00 100 GANAB
65 11 63389016 64780509 1 1 3.1e-07 8.5e-06 1.7e-01 90 PRDX5
66 11 65405300 67192555 6 1 5.0e-12 5.5e-12 1.6e-02 88 B3GNT1
67 11 87146898 88606591 1 1 5.9e-08 3.6e-07 5.5e-02 86 RAB38
68 11 89354278 90716657 1 1 5.2e-08 2.4e-08 4.6e-02 87 RP11-121L10.3
69 11 94805896 96276010 4 1 1.5e-14 3.3e-12 3.3e-01 98 CEP57
70 11 101404645 102797829 1 1 1.7e-07 1.7e-07 1.0e+00 100 RP11-864G5.3
71 11 122897730 124309814 1 1 1.0e-09 6.1e-07 1.1e-03 57 ZNF202
72 12 55677395 57125879 5 1 8.8e-12 3.3e-11 1.0e+00 100 RPS26
73 12 122258047 124774793 13 2 1.0e-12 7.4e-12 7.6e-01 100 ABCB9 ARL6IP4
74 13 31078511 32595740 1 1 8.6e-10 9.3e-09 1.9e-02 83 B3GALTL
75 13 98109395 99925872 3 1 5.4e-10 8.0e-08 8.0e-01 100 STK24
76 13 100487469 101940873 1 1 1.9e-07 1.0e-08 3.5e-04 61 GGACT
77 14 22670975 24147787 4 1 6.1e-08 5.3e-08 1.0e+00 100 RP11-298I3.1
78 14 26213713 27761335 1 2 7.4e-08 5.6e-14 2.0e-07 52 NOVA1
79 14 69027866 70518587 1 1 2.2e-10 3.5e-09 1.7e-02 84 GALNT16
80 14 71712035 73729498 1 1 5.5e-08 7.7e-09 5.3e-05 51 RGS6
81 14 102891646 104892153 7 1 2.0e-11 2.3e-11 4.5e-02 91 TRMT61A
82 15 46780520 48764942 1 1 1.9e-07 3.2e-12 2.4e-08 36 SEMA6D
83 15 81734963 83670356 3 2 1.4e-07 5.9e-06 2.9e-01 95 EFTUD1 RP11-152F13.7
84 16 86671 1962132 11 2 1.7e-09 1.3e-09 1.5e-04 61 CACNA1H WDR24
85 16 11326785 12767048 1 1 8.7e-08 1.1e-07 2.1e-05 36 RP11-166B2.1
86 16 14323446 15921958 3 1 6.7e-08 2.9e-06 5.7e-01 98 RP11-1186N24.5
87 16 27412414 30703155 27 2 3.5e-14 8.6e-13 6.8e-01 100 INO80E SH2B1
88 16 52772129 54235440 2 1 8.5e-09 3.0e-11 3.2e-04 71 AKTIP
89 16 71070698 72657531 4 1 1.6e-09 2.6e-07 8.5e-01 100 IST1
90 17 17747289 18923818 1 1 3.4e-10 1.7e-06 2.7e-01 95 CCDC144B
91 17 29028281 30556282 1 1 2.2e-07 7.3e-07 1.5e-01 91 RAB11FIP4
92 17 37125922 38512197 1 1 8.8e-08 1.7e-05 1.3e-01 88 TCAP
93 17 42774693 45796313 20 1 2.4e-13 2.8e-11 9.4e-01 100 DND1
94 17 60930216 62363978 1 1 4.0e-07 1.6e-06 1.0e+00 100 DCAF7
95 19 1473344 2923263 1 1 9.5e-08 6.6e-06 5.0e-04 40 DOT1L
96 19 17562969 19237273 5 1 5.9e-09 3.4e-10 2.3e-04 66 AC007192.6
97 19 32209988 33668090 1 1 1.2e-07 8.1e-09 2.1e-02 84 DPY19L3
98 19 35448803 36956110 3 1 5.9e-08 1.4e-07 1.0e+00 100 COX6B1
99 19 44894164 46506809 2 2 1.2e-09 1.5e-14 3.8e-05 71 GEMIN7 MARK4
100 20 2390880 3850968 3 1 1.1e-09 5.5e-08 9.1e-01 100 FASTKD5
101 20 32865844 34562581 4 1 5.0e-09 2.2e-08 4.0e-02 86 EDEM2
102 20 42924921 44448292 3 1 3.1e-12 3.8e-13 1.0e+00 100 STK4
103 20 57934675 59346576 1 1 4.1e-08 6.7e-09 8.7e-08 15 C20orf197
104 22 29485708 30932673 1 1 1.3e-07 1.4e-07 1.0e+00 100 ASCC2
105 22 39192995 40571499 1 1 3.0e-07 6.1e-09 1.5e-03 70 MGAT3
106 22 41424053 43615241 3 2 5.6e-08 2.2e-05 6.1e-01 98 RRP7A WBP2NL

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Crohns Disease (2017) 1.62 5 5 15.2 0.70 1.2e-01 FAM212A MON1A MST1R QRICH1 SH2B1
Irritable Bowel Disease (IBD) 2.05 6 5 15.2 0.71 7.4e-02 DR1 FAM212A MON1A MST1R QRICH1 SH2B1
Ulcerative Colitis (UC) 1.96 5 4 12.1 0.79 6.2e-02 FAM212A MON1A MST1R QRICH1 SH2B1
Major Depression (MDD) 2.01 2 1 3.0 0.00 1.0e+00 NEGR1 TRMT61A
Reaction Time 1.64 3 1 3.0 0.00 1.0e+00 CTD-2517M22.16 FOXO3 PFDN1
Verbal and Numeric Reasoning (VNR) 6.14 36 23 69.7 -0.97 3.1e-23 AFF3 AKTIP ARL6IP4 CALN1 CEP57 DCAF16 DNAH11 DND1 FAM160A1 FAM212A FBXO41 FOXO3 FOXO6 HPS6 IFT57 JMJD1C-AS1 LINC00461 LONRF2 MGAT3 MON1A MST1R NEGR1 NPM3 NR2F1-AS1 PFDN1 PPA2 QRICH1 RPS26 SH2B1 SND1 ST6GAL2 SYPL2 TANK TEX15 TRIM38 TRMT61A
Breast Cancer 1.19 3 2 6.1 0.00 1.0e+00 B3GNT1 DND1 RP11-767N6.2
Ovarian Cancer 1.21 1 1 3.0 0.00 1.0e+00 DND1
Prostate Cancer 1.69 3 1 3.0 0.00 1.0e+00 MDM4 MON1A PPA2
Age at First Birth 3.59 6 3 9.1 -0.99 9.5e-06 AFF3 CTD-2517M22.16 FAM212A MON1A MST1R PTPN23
Bipolar Disorder 1.76 1 0 0.0 0.00 1.0e+00 B3GNT1
Body Mass Index (BMI) (2010) 2.22 3 2 6.1 0.00 1.0e+00 NEGR1 SH2B1 TRIM73
Crohns Disease (2012) 1.71 5 4 12.1 -0.76 1.3e-01 FAM212A MON1A MST1R QRICH1 SH2B1
HDL Cholesterol 1.43 2 0 0.0 0.00 1.0e+00 DR1 TCAP
LDL Cholesterol 1.27 3 2 6.1 0.00 1.0e+00 DNAH11 GEMIN7 SYPL2
Neuroticism 1.75 5 1 3.0 0.71 1.8e-01 DND1 FTSJ2 LINC00461 STK24 TANK
Primary Biliary Cirrhosis 1.26 2 0 0.0 0.00 1.0e+00 DND1 TCAP
Schizophrenia 2.14 10 5 15.2 -0.35 3.2e-01 ABCB9 ACTR1A ARL6IP4 C2orf82 DPH2 FTSJ2 GNL3LP1 MGAT3 RP11-261C10.5 STK4
Ulcerative Colitis 1.91 4 3 9.1 -0.97 7.4e-03 FAM212A MON1A MST1R QRICH1
Blood Eosinophil Count 1.11 15 12 36.4 -0.03 9.1e-01 ABCB9 ADD3 CACNA1H DND1 DR1 FAM212A GPX1 INO80E MARK4 MON1A MST1R PRUNE RP11-298I3.1 RPS26 TATDN3
Blood Platelet Count 1.33 26 19 57.6 0.35 7.9e-02 ABCB9 ADD3 ARL6IP4 DCAF16 DCAF7 DND1 DR1 EDEM3 FAM160A1 GRK4 INO80E JMJD1C-AS1 LINC00461 MARK4 METTL10 MPP6 PRDX5 PSCA RP11-1084E5.1 RP11-767N6.2 RP11-864G5.3 RRP7A STAG3L5P-PVRIG2P-PILRB TCAP TRMT61A WDR24
Blood Red Count 1.44 19 15 45.5 0.12 6.2e-01 AFF3 ARL6IP4 CEP57 CTC-498M16.2 CTD-2517M22.16 DND1 DR1 EFTUD1 FAM212A HYI INO80E LINC00461 PTPN23 RABGAP1L RP11-767N6.2 RPS26 SH2B1 TCAP TIE1
Blood White Count 1.58 30 19 57.6 0.57 6.1e-04 ACTR1A ASCC2 CACNA1H CAMKMT CTC-498M16.2 DCAF16 DCAF7 DND1 FAM160A1 FAM212A FASTKD5 GEMIN7 GRK4 INO80E JMJD1C-AS1 MARK4 MGAT3 MON1A MST1R PPA2 PRUNE PTPN23 QRICH1 RP11-864G5.3 RRP7A SEMA6D STAG3L5P-PVRIG2P-PILRB TEX15 TIE1 TRMT61A
Heel T-Score 1.27 20 15 45.5 0.17 4.6e-01 ABCB9 ARL6IP4 ASCC2 C2orf82 DCAF16 DCAF7 DND1 EDEM2 FAM212A INO80E METTL10 MST1R NEGR1 RAB11FIP4 RP11-166B2.1 RP11-767N6.2 RPS26 STAG3L5P-PVRIG2P-PILRB TRMT61A WBP2NL
BMI 3.41 35 27 81.8 0.64 2.8e-05 ABCB9 ACTR1A AFF3 CPNE3 CTC-498M16.2 DCAF7 DOT1L EDEM3 FAM212A FOXO3 GALNT16 GPX1 GRK4 IFT57 INO80E LINC00461 LONRF2 MON1A MST1R NAT6 NEGR1 NR2F1-AS1 PRDX5 PRUNE PTPN23 QRICH1 RGS6 RPS26 SH2B1 STAG3L5P-PVRIG2P-PILRB STK24 SYPL2 TDGF1P2 TEX15 TRIM73
Height 2.25 47 39 118.2 -0.52 1.7e-04 ABCB9 AKTIP ARL6IP4 C2orf82 CACNA1H CAMKMT CCDC144B CEP57 COX6B1 CPNE3 DCAF16 DCAF7 DCP2 DNA2 DND1 DR1 EDEM2 ELOVL7 FAM160A1 FASTKD5 FOXO3 GGACT HYI INO80E IST1 MDM4 METTL10 MGAT3 MPP6 PPA2 PPP2R2D PRUNE PSCA PTPN23 RAB11FIP4 RP11-1186N24.5 RP11-166B2.1 RP11-767N6.2 RP11-864G5.3 SH2B1 STAG3L5P-PVRIG2P-PILRB STK4 TBCE TIE1 TRIM73 TRMT61A WDR24
Waist Hip Ratio (WHR) 1.55 13 9 27.3 0.97 1.8e-08 ABCB9 AC007192.6 AFF3 AKTIP ARL6IP4 CCDC144B DND1 EDEM2 GANAB GNL3LP1 MGAT3 PRDX5 SEMA6D
Systolic Blood Pressure 1.71 19 10 30.3 0.08 7.3e-01 ACTR1A CCDC144B DCAF16 DND1 EDEM2 EDEM3 FBXO41 FOXO3 HYI MPP6 PPP2R2D PRDX5 PTPN23 RP11-166B2.1 RP11-298I3.1 SND1 ST6GAL2 TIE1 TRIM73
Smoking Status 3.37 20 9 27.3 0.85 1.6e-06 ACTR1A CELF2 DND1 DPH2 EFTUD1 ELOVL7 GGACT GNL3LP1 IFT57 LONRF2 MST1R NAT6 PTK2 PTPN23 RABGAP1L RP11-767N6.2 RPS26 SEMA6D TANK WDR24
Allergy or Eczema 1.35 5 1 3.0 -0.89 4.1e-02 DR1 NEGR1 PRUNE RPS26 SH2B1
Cardiovascular Disease 1.60 9 3 9.1 0.42 2.6e-01 DCAF16 DCAF7 FBXO41 GRK4 NEGR1 RP11-261C10.5 TEX15 TIE1 TRIM73
Hypothyroidism (self reported) 1.48 3 2 6.1 0.00 1.0e+00 PTK2 RPS26 TANK
Respiratory disease 1.59 5 2 6.1 0.48 4.2e-01 MON1A MST1R RABGAP1L RPS26 TCAP
Type 2 Diabetes (T2D) 1.73 4 1 3.0 0.96 7.9e-03 AKTIP FAM212A MON1A MST1R
Lung FEV1/FVC ratio 1.46 15 13 39.4 0.22 4.3e-01 ACTR1A ADD3 ASCC2 CCDC144B DND1 FOXO3 GANAB GPX1 JMJD1C-AS1 NEGR1 PPA2 RP11-298I3.1 RP11-767N6.2 RPS26 STAG3L5P-PVRIG2P-PILRB
Lung FVC 1.84 20 12 36.4 -0.17 4.8e-01 ARL6IP4 B3GNT1 CTD-2517M22.16 DCAF16 DNA2 DND1 EDEM2 FOXO3 FOXO6 JMJD1C-AS1 MDM4 MON1A MST1R NR2F1-AS1 PFDN1 RP11-1084E5.1 RP11-152F13.7 RPS26 SH2B1 TCAP
Neuroticism 2.28 9 4 12.1 0.69 4.0e-02 B3GALTL CTC-498M16.2 DND1 GALNT16 GPX1 LINC00461 MON1A RABGAP1L STK24
Chronotype (morning person) 1.46 2 0 0.0 0.00 1.0e+00 MON1A MST1R
Hair Pigment 0.27 8 4 12.1 0.45 2.7e-01 ADD3 ARL6IP4 B3GNT1 DND1 EDEM2 FOXO3 JMJD1C-AS1 RPS26
Tanning 0.52 3 2 6.1 0.00 1.0e+00 EDEM2 IST1 PFDN1
Hand grip strength (left) 1.88 7 5 15.2 0.13 7.9e-01 ACTR1A CALN1 DCAF16 DND1 EDEM2 NPM3 STAG3L5P-PVRIG2P-PILRB
Number of treatments/medications taken 2.86 10 5 15.2 -0.97 9.1e-07 B3GALTL DCAF16 FAM212A FBXO41 MON1A MST1R PPP2R2D RABGAP1L ST6GAL2 TANK
Average weekly spirits intake 1.78 1 0 0.0 0.00 1.0e+00 QRICH1
Sensitivity / hurt feelings 1.81 1 1 3.0 0.00 1.0e+00 DND1
Frequency of depressed mood in last 2 weeks 1.67 1 1 3.0 0.00 1.0e+00 JMJD1C-AS1
Hearing difficulty/problems: Yes 1.39 2 2 6.1 0.00 1.0e+00 PTK2 RP11-767N6.2
Relative age of first facial hair 1.81 4 1 3.0 -0.34 6.6e-01 DND1 FOXO3 PRUNE RABGAP1L
Systolic blood pressure, automated reading 1.91 10 5 15.2 -0.47 1.5e-01 DCAF16 DND1 EDEM2 EDEM3 FBXO41 MPP6 PPA2 RP11-298I3.1 TIE1 TRIM73
Medication: Co-codamol 2.02 2 0 0.0 0.00 1.0e+00 MON1A MST1R
Pack years adult smoking proportion 2.15 6 1 3.0 -0.98 6.7e-04 BNIP3 GPX1 GRK4 JMJD1C-AS1 SEMA6D SH2B1
Impedance of leg (right) 1.98 25 14 42.4 0.14 4.9e-01 ABCB9 ACTR1A AKTIP B3GNT1 DNA2 EDEM2 FAM160A1 FAM212A INO80E LINC00461 MON1A MST1R NAT6 NEGR1 PPA2 PRR7 PTK2 PTPN23 RGS6 RPS26 SEMA6D SH2B1 STAG3L5P-PVRIG2P-PILRB SYPL2 TRIM73
Leg fat-free mass (left) 2.80 28 22 66.7 -0.07 7.2e-01 ABCB9 ACTR1A AFF3 AKTIP ARL6IP4 CTC-498M16.2 DCAF16 DCAF7 DNA2 EDEM2 FAM160A1 FAM212A FOXO3 INO80E LINC00461 MGAT3 MON1A MST1R NAT6 NEGR1 PPA2 PRDX5 RPS26 SH2B1 SYPL2 TRIM38 TRIM73 WDR24
Trunk fat percentage 2.63 23 12 36.4 -0.59 2.2e-03 ABCB9 AC007192.6 AFF3 DNA2 DND1 EDEM3 FAM212A FOXO3 GALNT16 INO80E LINC00461 LONRF2 METTL10 MON1A MPP6 MST1R NEGR1 PSCA QRICH1 SH2B1 STK24 TEX15 TRIM73
Hand grip strength (right) 1.94 7 4 12.1 0.39 3.9e-01 ACTR1A DCAF16 DCAF7 DND1 EDEM2 NPM3 STAG3L5P-PVRIG2P-PILRB
Townsend deprivation index at recruitment 2.05 1 0 0.0 0.00 1.0e+00 MARK4
Current tobacco smoking 2.69 4 2 6.1 -0.97 3.5e-02 ACTR1A DPH2 PRR7 SEMA6D
Maternal smoking around birth 2.77 4 1 3.0 -0.95 5.0e-02 ACTR1A DPH2 MST1R NAT6
Fed-up feelings 3.27 10 4 12.1 -0.84 1.3e-03 B3GNT1 DND1 FAM212A GALNT16 GPX1 LINC00461 MON1A MST1R PRDX5 QRICH1
Frequency of unenthusiasm / disinterest in last 2 weeks 2.41 2 2 6.1 0.00 1.0e+00 GALNT16 JMJD1C-AS1
Relative age voice broke 1.64 2 1 3.0 0.00 1.0e+00 DND1 FOXO3
Taking other prescription medications 2.38 4 3 9.1 -0.99 6.4e-04 B3GALTL FAM212A MON1A MST1R
Age when periods started (menarche) 2.41 12 9 27.3 -0.54 3.6e-02 COX6B1 DPH2 FOXO3 HYI INO80E MON1A MST1R NAT6 NEGR1 RRP7A TIE1 TRIM73
Heel bone mineral density (BMD) T-score, automated (left) 1.15 3 1 3.0 0.00 1.0e+00 EDEM2 FAM212A MST1R
Qualifications: CSEs or equivalent 2.93 2 0 0.0 0.00 1.0e+00 FOXO6 MST1R
High blood pressure 1.76 8 1 3.0 -0.14 7.5e-01 DCAF16 FBXO41 NEGR1 PTK2 RP11-261C10.5 TEX15 TIE1 TRIM73
Hayfever, allergic rhinitis or eczema 1.31 1 1 3.0 0.00 1.0e+00 RPS26
Medication: Levothyroxine sodium 1.36 1 1 3.0 0.00 1.0e+00 RPS26
Sitting height 2.46 19 13 39.4 0.80 4.0e-05 ABCB9 AKTIP ARL6IP4 C2orf82 DCAF16 DCAF7 DNA2 DND1 DPH2 EDEM2 FOXO3 HYI MGAT3 PPA2 PPP2R2D RP11-767N6.2 TIE1 TRIM38 WDR24
Body mass index (BMI) 3.53 29 16 48.5 -0.77 7.8e-07 ACTR1A AFF3 CPNE3 CTC-498M16.2 DCAF7 DOT1L EDEM3 FAM212A FOXO3 GPX1 GRK4 IFT57 INO80E LINC00461 LONRF2 MON1A MPP6 MST1R NAT6 NEGR1 PTPN23 QRICH1 RGS6 RPS26 SH2B1 STK24 TEX15 TNKS TRIM73
Impedance of leg (left) 2.04 25 17 51.5 0.13 5.3e-01 ABCB9 ACTR1A AKTIP B3GNT1 DNA2 EDEM2 FAM160A1 FAM212A INO80E LINC00461 MON1A MST1R NAT6 NEGR1 PPA2 PRR7 PTK2 PTPN23 RGS6 RPS26 SEMA6D SH2B1 STAG3L5P-PVRIG2P-PILRB SYPL2 TRIM73
Leg predicted mass (left) 2.81 27 22 66.7 -0.08 6.9e-01 ABCB9 ACTR1A AFF3 AKTIP ARL6IP4 CTC-498M16.2 DCAF16 DCAF7 DNA2 EDEM2 FAM160A1 FAM212A FOXO3 INO80E LINC00461 MGAT3 MON1A MST1R NAT6 NEGR1 PPA2 PRDX5 RPS26 SH2B1 SYPL2 TRIM38 TRIM73
Trunk fat mass 2.79 22 19 57.6 -0.54 7.8e-03 ABCB9 AC007192.6 AFF3 CTC-498M16.2 EDEM2 FAM212A FOXO3 GALNT16 INO80E LINC00461 LONRF2 METTL10 MON1A MST1R NEGR1 PRDX5 PSCA RGS6 SH2B1 STK24 TEX15 TRIM73
Waist circumference 2.89 18 14 42.4 -0.68 1.3e-03 AC007192.6 AFF3 CTC-498M16.2 FAM212A FOXO3 INO80E LINC00461 LONRF2 MON1A MST1R NAT6 NEGR1 RGS6 RPS26 SH2B1 STK24 TEX15 TRIM73
Number of incorrect matches in round 1.89 2 2 6.1 0.00 1.0e+00 INO80E NPM3
Past tobacco smoking 2.33 9 1 3.0 0.97 2.5e-05 ACTR1A DPH2 EDEM2 GGACT GNL3LP1 NAT6 PTPN23 TANK WDR24
Alcohol usually taken with meals 3.73 10 3 9.1 0.97 3.8e-07 ACTR1A AFF3 DPH2 ELOVL7 GNL3LP1 HYI LONRF2 NEGR1 RABGAP1L TIE1
Nervous feelings 1.65 6 3 9.1 -0.35 5.0e-01 ACTR1A B3GALTL CTC-498M16.2 DND1 INO80E STK24
Frequency of tenseness / restlessness in last 2 weeks 1.86 3 2 6.1 0.00 1.0e+00 B3GALTL DND1 MST1R
Hair/balding pattern: Pattern 2 1.02 1 0 0.0 0.00 1.0e+00 GGACT
Had other major operations 1.74 1 0 0.0 0.00 1.0e+00 PPA2
Forced vital capacity (FVC) 2.00 8 5 15.2 0.79 2.1e-02 DCAF16 DCAF7 DND1 IST1 MDM4 MST1R PPA2 PPP2R2D
Heel bone mineral density (BMD) T-score, automated (right) 1.19 4 1 3.0 -0.82 1.8e-01 DCAF16 EDEM2 FAM212A MST1R
Ever unenthusiastic/disinterested for a whole week 1.54 1 0 0.0 0.00 1.0e+00 DND1
Qualifications: None of the above 8.56 57 31 93.9 -0.98 1.0e-42 ABCB9 ACTR1A AFF3 AKTIP ARL6IP4 B3GALTL B3GNT1 BAI1 BNIP3 CALN1 CELF2 CEP57 CTC-498M16.2 DPH2 DR1 ELOVL7 FAM160A1 FAM212A FOXO3 FPGT FTSJ2 GNL3LP1 GPX1 GRK4 HPS6 HYI IFT57 IST1 JMJD1C-AS1 LONRF2 MAN2A1 MARK4 MON1A MPP6 MST1R NAT6 NEGR1 NOVA1 NPM3 NR2F1-AS1 PPA2 PPP2R2D PRR7 PSCA PTPN23 QRICH1 RP11-1186N24.5 RP11-261C10.5 RPS26 SH2B1 ST6GAL2 SYPL2 TANK TEX15 TIE1 TRIM38 WDR24
Financial difficulties in last 2 years 1.92 2 0 0.0 0.00 1.0e+00 AFF3 LONRF2
Mouth/teeth dental problems 2.03 3 0 0.0 0.00 1.0e+00 DND1 PTK2 RP11-261C10.5
Allergy 1.33 1 1 3.0 0.00 1.0e+00 RPS26
Diabetes (self-reported) 1.91 3 0 0.0 0.00 1.0e+00 AKTIP FAM212A MON1A
Hayfever/allergic rhinitis (self-reported) 1.38 1 1 3.0 0.00 1.0e+00 RPS26
Fluid intelligence score 5.92 35 17 51.5 0.98 1.1e-25 AFF3 AKTIP ARL6IP4 BNIP3 C20orf197 CALN1 CTD-2517M22.16 CTD-3025N20.2 DCAF16 DND1 DPH2 FAM160A1 FAM212A FBXO41 FOXO3 FOXO6 HPS6 IFT57 JMJD1C-AS1 LONRF2 MGAT3 MON1A MST1R NEGR1 NPM3 NR2F1-AS1 PFDN1 PPA2 RPS26 SH2B1 ST6GAL2 STAG3L5P-PVRIG2P-PILRB SYPL2 TANK TRMT61A
Neuroticism score 2.25 9 3 9.1 -0.72 2.9e-02 B3GALTL DND1 GALNT16 GPX1 LINC00461 MON1A RABGAP1L STK24 TNKS
Weight 3.01 24 18 54.5 -0.44 2.9e-02 ABCB9 ACTR1A AFF3 AKTIP CTC-498M16.2 DCAF16 EDEM2 FAM212A FOXO3 IFT57 INO80E LINC00461 LONRF2 MON1A MST1R NAT6 NEGR1 PRDX5 PSCA RPS26 SH2B1 TEX15 TRIM38 TRIM73
Impedance of arm (right) 2.23 23 15 45.5 0.66 4.5e-04 ACTR1A AFF3 CTC-498M16.2 DND1 EDEM2 ELOVL7 FAM212A FOXO3 GPX1 INO80E JMJD1C-AS1 MON1A MST1R NAT6 NEGR1 PRUNE RGS6 RP11-864G5.3 RPS26 STAG3L5P-PVRIG2P-PILRB SYPL2 TRIM73 WBP2NL
Arm fat percentage (right) 2.97 25 14 42.4 -0.68 1.5e-04 AC007192.6 AFF3 CTC-498M16.2 DCAF16 DCAF7 DNA2 EDEM3 FAM212A FOXO3 IFT57 INO80E LINC00461 LONRF2 MON1A MPP6 MST1R NEGR1 QRICH1 RGS6 SEMA6D SH2B1 STK24 TEX15 TNKS TRIM73
Trunk fat-free mass 2.80 29 21 63.6 0.01 9.6e-01 ABCB9 ACTR1A AFF3 AKTIP ARL6IP4 CTC-498M16.2 DCAF16 DCAF7 DNA2 EDEM2 ELOVL7 FAM160A1 FAM212A FOXO3 GNL3LP1 INO80E MGAT3 MON1A MST1R NAT6 NEGR1 PPA2 RPS26 SH2B1 SYPL2 TRIM38 TRMT61A WBP2NL WDR24
Hip circumference 2.70 22 16 48.5 -0.35 9.7e-02 ABCB9 ACTR1A AFF3 AKTIP CTC-498M16.2 DCAF16 EDEM2 FAM212A FOXO3 INO80E LINC00461 LONRF2 MON1A MST1R NAT6 NEGR1 PRDX5 PSCA SH2B1 TEX15 TRIM38 TRIM73
Alcohol intake versus 10 years previously 2.78 5 4 12.1 -0.74 9.0e-02 DPH2 FAM212A MON1A MST1R NEGR1
Father's age at death 1.94 1 0 0.0 0.00 1.0e+00 QRICH1
Worrier / anxious feelings 1.93 5 1 3.0 0.21 7.4e-01 ACTR1A B3GALTL DND1 DPH2 TNKS
Frequency of tiredness / lethargy in last 2 weeks 1.93 2 0 0.0 0.00 1.0e+00 GALNT16 JMJD1C-AS1
Falls in the last year 1.40 1 0 0.0 0.00 1.0e+00 TCAP
Hair/balding pattern: Pattern 3 1.59 2 1 3.0 0.00 1.0e+00 DND1 GGACT
Forced expiratory volume in 1-second (FEV1) 2.16 12 6 18.2 0.67 1.7e-02 DCAF16 DCAF7 DND1 GPX1 GRK4 MDM4 MST1R PPA2 PPP2R2D QRICH1 RPS26 TRIM38
Pulse rate 1.27 1 1 3.0 0.00 1.0e+00 AKTIP
Noisy workplace 2.64 2 0 0.0 0.00 1.0e+00 MARK4 SYPL2
Qualifications: A levels/AS levels or equivalent 8.10 51 19 57.6 0.99 7.5e-43 ABCB9 AC007192.6 ACTR1A AFF3 ARL6IP4 BAI1 CAMKMT CELF2 CEP57 CPNE3 CTD-3025N20.2 DCAF16 DDX31 DNAH11 DND1 DPH2 DR1 EDEM2 ELOVL7 FAM160A1 FAM212A FASTKD5 FBXO41 FOXO6 FTSJ2 GNL3LP1 HYI IFT57 JMJD1C-AS1 LONRF2 MARK4 MGAT3 MON1A MPP6 MST1R NEGR1 NPM3 PPA2 PSCA QRICH1 RAB11FIP4 RP11-261C10.5 RPS26 RRP7A ST6GAL2 TANK TIE1 TRIM38 TRIM73 TRMT61A WDR24
Mouth/teeth dental problems: Dentures 2.71 6 3 9.1 -0.95 1.1e-03 DMAP1 DR1 FAM212A INO80E MON1A MST1R
Asthma 1.64 4 3 9.1 0.17 8.3e-01 AFF3 RPS26 TCAP TRIM38
Forced expiratory volume in 1-second (FEV1), Best measure 2.19 9 7 21.2 0.59 9.1e-02 DCAF16 DCAF7 DND1 GPX1 MDM4 MST1R PPA2 RPS26 TRIM38
Impedance of arm (left) 2.21 22 18 54.5 0.67 4.3e-04 ACTR1A AFF3 CTC-498M16.2 DND1 EDEM2 ELOVL7 FAM212A FOXO3 GPX1 INO80E JMJD1C-AS1 MON1A MST1R NAT6 NEGR1 PRUNE RP11-864G5.3 RPS26 STAG3L5P-PVRIG2P-PILRB SYPL2 TRIM73 WBP2NL
Arm fat mass (right) 3.21 28 14 42.4 -0.61 4.2e-04 ABCB9 AC007192.6 AFF3 CTC-498M16.2 EDEM2 EDEM3 FAM212A FOXO3 GPX1 IFT57 INO80E LINC00461 LONRF2 METTL10 MON1A MST1R NAT6 NEGR1 PRDX5 PSCA QRICH1 RGS6 RPS26 SH2B1 STK24 TEX15 TNKS TRIM73
Trunk predicted mass 2.80 29 21 63.6 0.02 9.4e-01 ABCB9 ACTR1A AFF3 AKTIP ARL6IP4 CTC-498M16.2 DCAF16 DCAF7 DNA2 EDEM2 ELOVL7 FAM160A1 FAM212A FOXO3 GNL3LP1 INO80E MGAT3 MON1A MST1R NAT6 NEGR1 PPA2 RPS26 SH2B1 SYPL2 TRIM38 TRMT61A WBP2NL WDR24
Standing height 2.43 31 18 54.5 0.65 5.3e-05 ABCB9 AKTIP ARL6IP4 C2orf82 CACNA1H CCDC144B COX6B1 DCAF16 DCAF7 DNA2 DND1 EDEM2 FAM160A1 FOXO3 GGACT GRK4 MPP6 PPA2 PPP2R2D PSCA PTPN23 RAB11FIP4 RP11-767N6.2 RRP7A SH2B1 STAG3L5P-PVRIG2P-PILRB TBCE TIE1 TRIM38 TRIM73 WDR24
Exposure to tobacco smoke at home 1.79 2 0 0.0 0.00 1.0e+00 MON1A MST1R
Tense / 'highly strung' 1.40 1 0 0.0 0.00 1.0e+00 RABGAP1L
Seen doctor (GP) for nerves, anxiety, tension or depression 2.02 2 1 3.0 0.00 1.0e+00 B3GALTL NEGR1
Hair/balding pattern: Pattern 4 1.32 2 1 3.0 0.00 1.0e+00 DND1 METTL10
Birth weight of first child 1.94 6 3 9.1 0.59 2.1e-01 DCAF16 PPA2 PTK2 RP11-864G5.3 RPS26 TRIM73
Peak expiratory flow (PEF) 1.78 6 2 6.1 0.76 8.3e-02 DCAF16 DND1 EDEM2 FOXO3 MDM4 NR2F1-AS1
Ever highly irritable/argumentative for 2 days 2.23 2 0 0.0 0.00 1.0e+00 MON1A MST1R
Qualifications: O levels/GCSEs or equivalent 4.12 9 0 0.0 0.93 2.2e-04 ARL6IP4 BAI1 CEP57 DMAP1 DPH2 FTSJ2 IFT57 MPP6 MST1R
Mouth/teeth dental problems: Bleeding gums 1.60 1 0 0.0 0.00 1.0e+00 SND1
Medication: Paracetamol 2.44 5 3 9.1 -0.96 8.9e-03 DND1 DR1 PTK2 RABGAP1L RP11-261C10.5
Headache pain in last month 1.65 3 2 6.1 0.00 1.0e+00 DND1 RP11-261C10.5 RPS26
Medication for cholesterol, blood pressure or diabetes 1.74 1 0 0.0 0.00 1.0e+00 FAM212A
Hypothyroidism/myxoedema (self-reported) 1.35 2 1 3.0 0.00 1.0e+00 RPS26 TANK
Medication: Ventolin 100micrograms inhaler 1.56 1 0 0.0 0.00 1.0e+00 RPS26
Birth weight 1.98 7 3 9.1 0.51 2.4e-01 DCAF16 DNA2 PPA2 PTK2 RARS2 RP11-864G5.3 SND1
Chronic bronchitis/emphysema (mother) 1.70 2 0 0.0 0.00 1.0e+00 MON1A MST1R
Forced vital capacity (FVC), Best measure 2.05 8 5 15.2 0.80 1.8e-02 DCAF16 DCAF7 DND1 IST1 MDM4 MST1R PPA2 TRIM38
Body fat percentage 3.05 27 15 45.5 -0.74 8.4e-06 AC007192.6 AFF3 CTC-498M16.2 DCAF16 DCAF7 DNA2 EDEM3 FAM212A FOXO3 GALNT16 GRK4 INO80E LINC00461 LONRF2 METTL10 MON1A MPP6 MST1R NEGR1 PSCA QRICH1 RGS6 RP11-121L10.3 SH2B1 STK24 TEX15 TRIM73
Leg fat percentage (right) 3.71 32 20 60.6 -0.79 5.2e-08 AC007192.6 AFF3 BNIP3 CEP57 CPNE3 CTC-498M16.2 DCAF16 DCAF7 DNA2 EDEM3 FAM212A FOXO3 GALNT16 GPX1 GRK4 IFT57 INO80E LINC00461 LONRF2 MON1A MPP6 MST1R NEGR1 QRICH1 RGS6 RP11-767N6.2 RPF2 SH2B1 STK24 TDGF1P2 TEX15 TRIM73
Arm fat-free mass (right) 2.91 29 20 60.6 -0.13 4.9e-01 ABCB9 ACTR1A AFF3 AKTIP ARL6IP4 CTC-498M16.2 DCAF16 DCAF7 DNA2 EDEM2 ELOVL7 FAM160A1 FAM212A FOXO3 INO80E LINC00461 MGAT3 MON1A MST1R NAT6 NEGR1 PPA2 RP11-864G5.3 RPS26 SH2B1 SYPL2 TRIM38 TRMT61A WBP2NL
Exposure to tobacco smoke outside home 2.46 3 0 0.0 0.00 1.0e+00 ELOVL7 MON1A MST1R
Comparative body size at age 10 2.04 7 5 15.2 -0.13 7.8e-01 CTC-498M16.2 FPGT NAT6 NEGR1 PRUNE PTPN23 SH2B1
Worry too long after embarrassment 1.70 4 1 3.0 -0.37 6.3e-01 DND1 LINC00461 PFDN1 PSCA
Seen a psychiatrist for nerves, anxiety, tension or depression 1.41 1 0 0.0 0.00 1.0e+00 TRMT61A
Wheeze or whistling in the chest in last year 2.44 6 3 9.1 -0.97 2.1e-04 AFF3 DOT1L FAM212A MON1A MST1R RABGAP1L
Reason for reducing amount of alcohol drunk: Health precaution 1.72 1 0 0.0 0.00 1.0e+00 CTC-498M16.2
Age at first live birth 4.62 10 4 12.1 0.99 1.8e-09 C20orf197 CEP57 CPNE3 DCAF16 DPH2 FAM212A GPX1 MON1A MST1R RPS26
Medication for pain relief, constipation, heartburn 2.29 7 1 3.0 0.99 1.0e-05 CEP57 DND1 PTK2 RABGAP1L RP11-261C10.5 ST6GAL2 TEX15
Neck or shoulder pain in last month 2.19 2 0 0.0 0.00 1.0e+00 INO80E RPS26
Medication: Blood pressure 1.71 2 0 0.0 0.00 1.0e+00 DCAF16 FBXO41
Mean time to correctly identify matches 1.71 4 2 6.1 0.44 5.6e-01 FAM212A FOXO3 IFT57 PFDN1
Whole body fat mass 3.13 26 16 48.5 -0.63 4.5e-04 ABCB9 AC007192.6 AFF3 CTC-498M16.2 EDEM2 EDEM3 FAM212A FOXO3 GALNT16 GPX1 IFT57 INO80E LINC00461 LONRF2 METTL10 MON1A MPP6 MST1R NEGR1 PSCA QRICH1 RGS6 SH2B1 STK24 TEX15 TRIM73
Leg fat mass (right) 3.52 30 15 45.5 -0.71 7.6e-06 ABCB9 AC007192.6 ACTR1A AFF3 CPNE3 CTC-498M16.2 EDEM3 FAM212A FOXO3 GALNT16 GPX1 IFT57 INO80E LINC00461 LONRF2 METTL10 MON1A MPP6 MST1R NAT6 NEGR1 PSCA QRICH1 RGS6 RPS26 SH2B1 STK24 TDGF1P2 TEX15 TRIM73
Arm predicted mass (right) 2.94 28 19 57.6 -0.17 3.7e-01 ABCB9 ACTR1A AFF3 AKTIP CTC-498M16.2 DCAF16 DCAF7 DNA2 EDEM2 ELOVL7 FAM160A1 FAM212A FOXO3 INO80E LINC00461 MGAT3 MON1A MST1R NAT6 NEGR1 PPA2 RP11-864G5.3 RPS26 SH2B1 SYPL2 TRIM38 TRMT61A WBP2NL
Pulse rate, automated reading 1.77 12 5 15.2 -0.26 4.2e-01 AKTIP CTC-498M16.2 EDEM2 FAM212A HYI LINC00461 MST1R NEGR1 PTPN23 RABGAP1L RP11-864G5.3 TRIM73
Alcohol intake frequency. 3.13 17 8 24.2 -0.83 2.5e-05 ARL6IP4 B3GALTL BAI1 BNIP3 CCDC144B CTC-498M16.2 DND1 FAM212A GALNT16 INO80E IST1 MON1A MST1R NEGR1 SH2B1 STAG3L5P-PVRIG2P-PILRB TEX15
Comparative height size at age 10 2.29 20 16 48.5 0.52 1.4e-02 ABCB9 AKTIP ARL6IP4 CCDC144B DCAF16 DCAF7 DNA2 DND1 DR1 EDEM2 FAM160A1 FOXO3 HYI INO80E RAB11FIP4 RP11-767N6.2 SH2B1 TIE1 TRIM38 WDR24
Suffer from 'nerves' 1.46 2 1 3.0 0.00 1.0e+00 B3GALTL SH2B1
Overall health rating 4.01 15 8 24.2 -0.97 7.3e-10 AKTIP B3GALTL DOT1L FAM212A FASTKD5 GALNT16 GPX1 GRK4 MON1A MST1R RABGAP1L RGS6 RP11-261C10.5 TANK TEX15
Age at last live birth 3.50 5 3 9.1 0.99 4.3e-05 DMAP1 FAM212A MON1A MST1R NAT6
Family relationship satisfaction 1.30 1 0 0.0 0.00 1.0e+00 CEP57
Leg pain on walking 2.21 3 1 3.0 -1.00 1.7e-03 FAM212A MON1A MST1R
Qualifications: NVQ or HND or HNC or equivalent 2.57 1 0 0.0 0.00 1.0e+00 FAM212A
Knee pain experienced in last month 2.40 4 1 3.0 0.33 6.7e-01 EDEM2 MST1R PTK2 RP11-261C10.5
Hypertension (Self-reported) 1.68 8 1 3.0 -0.37 3.6e-01 AKTIP DCAF16 FBXO41 NEGR1 PTK2 RP11-261C10.5 TEX15 TRIM73
Smoking status: Previous 1.80 1 0 0.0 0.00 1.0e+00 GGACT
Forced expiratory volume in 1-second (FEV1), predicted 1.63 3 3 9.1 0.00 1.0e+00 DCAF16 DCAF7 EDEM2
Whole body fat-free mass 2.85 29 21 63.6 -0.01 9.6e-01 ABCB9 ACTR1A AFF3 AKTIP ARL6IP4 CTC-498M16.2 DCAF16 DCAF7 DNA2 EDEM2 ELOVL7 FAM160A1 FAM212A FOXO3 GNL3LP1 INO80E LINC00461 MGAT3 MON1A MST1R NAT6 NEGR1 PPA2 RPS26 SH2B1 SYPL2 TRIM38 TRMT61A WDR24
Leg fat-free mass (right) 2.76 28 21 63.6 -0.04 8.5e-01 ABCB9 ACTR1A AFF3 AKTIP ARL6IP4 CACNA1H CTC-498M16.2 DCAF16 DCAF7 DNA2 EDEM2 FAM160A1 FAM212A FOXO3 INO80E LINC00461 MGAT3 MON1A MST1R NAT6 NEGR1 PPA2 RPS26 SH2B1 SYPL2 TRIM38 TRIM73 WDR24
Arm fat percentage (left) 2.96 23 14 42.4 -0.70 1.3e-04 AC007192.6 AFF3 CTC-498M16.2 DCAF16 DCAF7 EDEM3 FAM212A GRK4 INO80E LINC00461 LONRF2 MON1A MPP6 MST1R NEGR1 QRICH1 RGS6 SEMA6D SH2B1 STK24 TEX15 TNKS TRIM73
Average weekly red wine intake 3.17 5 0 0.0 0.99 1.5e-03 ARL6IP4 B3GNT1 CEP57 CTC-498M16.2 DR1
Handedness (chirality/laterality): Left-handed 1.32 1 0 0.0 0.00 1.0e+00 DND1
Mood swings 2.61 8 2 6.1 -0.89 1.2e-03 CELF2 DND1 FAM212A GPX1 MON1A MST1R PTK2 STK24
Loneliness, isolation 1.91 1 0 0.0 0.00 1.0e+00 JMJD1C-AS1
Long-standing illness, disability or infirmity 2.05 2 0 0.0 0.00 1.0e+00 NEGR1 NR2F1-AS1
Ever had bowel cancer screening 1.43 2 0 0.0 0.00 1.0e+00 FAM212A MON1A
Diabetes diagnosed by doctor 1.73 2 0 0.0 0.00 1.0e+00 AKTIP FAM212A
Friendships satisfaction 1.98 1 0 0.0 0.00 1.0e+00 CEP57
Qualifications: nursing, teaching 5.45 12 4 12.1 0.96 1.2e-07 ABCB9 ARL6IP4 ELOVL7 FAM212A GALNT16 JMJD1C-AS1 METTL10 MON1A MST1R NEGR1 PPA2 STK24
Mouth/teeth dental problems: Mouth ulcers 1.40 3 1 3.0 0.00 1.0e+00 AC007192.6 CEP57 DND1
Back pain experienced in last month 2.28 1 0 0.0 0.00 1.0e+00 PTK2
Mineral and other dietary supplements 1.63 2 0 0.0 0.00 1.0e+00 CTC-498M16.2 GRK4
Asthma (self-reported) 1.62 4 2 6.1 0.17 8.3e-01 AFF3 RPS26 TCAP TRIM38
Smoking status: Current 2.68 4 2 6.1 -0.97 3.0e-02 ACTR1A DPH2 PRR7 SEMA6D
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.79 4 1 3.0 0.97 3.0e-02 DND1 INO80E PPA2 SH2B1
Whole body water mass 2.86 29 21 63.6 -0.01 9.4e-01 ABCB9 ACTR1A AFF3 AKTIP ARL6IP4 CTC-498M16.2 DCAF16 DCAF7 DNA2 EDEM2 ELOVL7 FAM160A1 FAM212A FOXO3 GNL3LP1 INO80E LINC00461 MGAT3 MON1A MST1R NAT6 NEGR1 PPA2 RPS26 SH2B1 SYPL2 TRIM38 TRMT61A WDR24
Leg predicted mass (right) 2.75 28 21 63.6 -0.03 8.6e-01 ABCB9 ACTR1A AFF3 AKTIP ARL6IP4 CACNA1H CTC-498M16.2 DCAF16 DCAF7 DNA2 EDEM2 FAM160A1 FAM212A FOXO3 INO80E LINC00461 MGAT3 MON1A MST1R NAT6 NEGR1 PPA2 RPS26 SH2B1 SYPL2 TRIM38 TRIM73 WDR24
Arm fat mass (left) 3.18 26 14 42.4 -0.60 9.7e-04 ABCB9 AC007192.6 AFF3 CTC-498M16.2 EDEM2 EDEM3 FAM212A FOXO3 IFT57 INO80E LINC00461 LONRF2 MON1A MST1R NAT6 NEGR1 PRDX5 PSCA QRICH1 RGS6 RPS26 SH2B1 STK24 TEX15 TNKS TRIM73
Number of self-reported non-cancer illnesses 1.92 2 1 3.0 0.00 1.0e+00 FBXO41 NEGR1
Average weekly champagne plus white wine intake 2.43 2 0 0.0 0.00 1.0e+00 DND1 WDR24
Miserableness 2.75 10 5 15.2 -0.95 7.4e-06 B3GALTL CELF2 DND1 FAM212A FTSJ2 GPX1 MON1A MST1R RABGAP1L RP11-261C10.5
Commuting to job workplace: Public transport 2.62 3 0 0.0 0.00 1.0e+00 AFF3 LONRF2 NEGR1
Supplements: Fish oil (including cod liver oil) 1.66 2 0 0.0 0.00 1.0e+00 B3GNT1 GRK4
High cholesterol (Self-reported) 1.21 1 0 0.0 0.00 1.0e+00 DCAF16
Medication: Bendroflumethiazide 1.39 1 1 3.0 0.00 1.0e+00 TEX15
Medication: Paracetamol 2.34 4 1 3.0 -0.99 1.0e-02 DND1 PTK2 RABGAP1L RP11-261C10.5
Ever smoked 2.17 6 1 3.0 -0.69 1.3e-01 ACTR1A GGACT GNL3LP1 PTPN23 WBP2NL WDR24
Basal metabolic rate 2.89 26 21 63.6 -0.11 5.9e-01 ABCB9 ACTR1A AFF3 AKTIP ARL6IP4 CTC-498M16.2 DCAF16 DCAF7 DNA2 EDEM2 FAM160A1 FAM212A FOXO3 INO80E LINC00461 MGAT3 MON1A MST1R NAT6 NEGR1 PPA2 RPS26 SH2B1 SYPL2 TRIM38 TRIM73
Leg fat percentage (left) 3.74 30 22 66.7 -0.79 1.5e-07 AC007192.6 AFF3 BNIP3 CPNE3 CTC-498M16.2 DCAF16 DCAF7 DNA2 EDEM3 FAM212A FOXO3 GALNT16 GPX1 GRK4 IFT57 INO80E LINC00461 LONRF2 MON1A MPP6 MST1R NEGR1 RGS6 RP11-767N6.2 RPF2 SH2B1 STK24 TDGF1P2 TEX15 TRIM73
Arm fat-free mass (left) 2.92 26 19 57.6 -0.19 3.5e-01 ABCB9 ACTR1A AFF3 AKTIP CTC-498M16.2 DCAF16 DCAF7 DNA2 EDEM2 ELOVL7 FAM160A1 FAM212A FOXO3 INO80E LINC00461 MGAT3 MON1A MST1R NAT6 NEGR1 PPA2 RP11-864G5.3 RPS26 SH2B1 TRIM38 TRMT61A
Number of operations (self-reported) 2.03 2 0 0.0 0.00 1.0e+00 MON1A MST1R
Average weekly beer plus cider intake 2.79 3 2 6.1 -1.00 4.7e-03 FAM212A MON1A MST1R
Irritability 1.60 3 2 6.1 0.00 1.0e+00 DND1 LINC00461 TRMT61A
Risk taking 1.68 2 0 0.0 0.00 1.0e+00 FAM160A1 RP11-261C10.5
Ever had prostate specific antigen (PSA) test 1.27 1 0 0.0 0.00 1.0e+00 CTC-498M16.2
Diastolic blood pressure, automated reading 2.29 16 9 27.3 -0.63 5.4e-03 ABCB9 ARL6IP4 DCAF16 EDEM3 FAM212A FBXO41 HYI LINC00461 MON1A MPP6 MST1R RP11-261C10.5 RP11-298I3.1 TIE1 TNKS TRIM73
Unable to work because of sickness or disability 2.21 1 0 0.0 0.00 1.0e+00 DOT1L
Myopia 1.90 1 0 0.0 0.00 1.0e+00 GGACT
Vascular/heart problems diagnosed by doctor 1.82 7 1 3.0 0.01 9.8e-01 DCAF16 FBXO41 HYI NEGR1 RP11-261C10.5 TEX15 TIE1
Cholesterol lowering medication 1.35 1 0 0.0 0.00 1.0e+00 DCAF16
Pain experienced in last month 2.80 5 1 3.0 0.97 1.5e-03 DND1 MON1A MST1R PTK2 RPS26
Pack years of smoking 2.03 1 1 3.0 0.00 1.0e+00 JMJD1C-AS1
Impedance of whole body 2.16 25 18 54.5 0.48 1.3e-02 ACTR1A AFF3 CTC-498M16.2 DND1 EDEM2 ELOVL7 FAM212A FOXO3 GPX1 INO80E JMJD1C-AS1 LINC00461 MON1A MST1R NAT6 NEGR1 PPA2 PRUNE PTK2 PTPN23 RGS6 RPS26 STAG3L5P-PVRIG2P-PILRB SYPL2 TRIM73
Leg fat mass (left) 3.55 29 15 45.5 -0.71 1.2e-05 ABCB9 AC007192.6 ACTR1A AFF3 CPNE3 CTC-498M16.2 EDEM3 FAM212A FOXO3 GALNT16 GPX1 IFT57 INO80E LINC00461 LONRF2 METTL10 MON1A MPP6 MST1R NAT6 NEGR1 QRICH1 RGS6 RPS26 SH2B1 STK24 TDGF1P2 TEX15 TRIM73
Arm predicted mass (left) 2.95 26 19 57.6 -0.19 3.5e-01 ABCB9 ACTR1A AFF3 AKTIP CTC-498M16.2 DCAF16 DCAF7 DNA2 EDEM2 ELOVL7 FAM160A1 FAM212A FOXO3 INO80E LINC00461 MGAT3 MON1A MST1R NAT6 NEGR1 PPA2 RP11-864G5.3 RPS26 SH2B1 TRIM38 TRMT61A

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 43 1.232 3.19
GTEx Adipose Visceral Omentum 33 1.621 3.42
GTEx Adrenal Gland 14 0.961 3.06
GTEx Artery Aorta 46 1.545 3.28
GTEx Artery Coronary 21 1.775 3.27
GTEx Artery Tibial 52 1.383 3.23
GTEx Brain Caudate basal ganglia 12 1.304 3.38
GTEx Brain Cerebellar Hemisphere 22 1.478 3.58
GTEx Brain Cerebellum 27 1.362 3.49
GTEx Brain Cortex 23 2.222 3.57
GTEx Brain Frontal Cortex BA9 16 1.732 3.74
GTEx Brain Hippocampus 8 1.527 3.39
GTEx Brain Hypothalamus 11 1.864 3.19
GTEx Brain Nucleus accumbens basal ganglia 13 1.503 3.47
GTEx Brain Putamen basal ganglia 9 1.442 3.76
GTEx Breast Mammary Tissue 33 1.672 3.49
GTEx Breast Mammary Tissue (Male) 13 1.090 3.15
GTEx Breast Mammary Tissue (Female) 26 1.582 3.35
GTEx Cells EBV-transformed lymphocytes 23 1.616 3.52
GTEx Cells Transformed fibroblasts 56 1.334 3.23
GTEx Colon Sigmoid 30 2.052 3.55
GTEx Colon Transverse 34 1.647 3.34
GTEx Esophagus Gastroesophageal Junction 28 1.938 3.63
GTEx Esophagus Mucosa 45 1.355 3.31
GTEx Esophagus Muscularis 48 1.485 3.44
GTEx Heart Atrial Appendage 22 1.393 3.42
GTEx Heart Left Ventricle 24 1.569 3.27
GTEx Liver 10 1.395 3.16
GTEx Lung 43 1.497 3.34
GTEx Muscle Skeletal 38 1.315 3.32
GTEx Nerve Tibial 56 1.296 3.19
GTEx Ovary 19 2.093 3.58
GTEx Pancreas 32 1.961 3.46
GTEx Pituitary 12 1.076 3.34
GTEx Prostate 15 1.796 3.50
GTEx Skin Not Sun Exposed Suprapubic 36 1.464 3.37
GTEx Skin Sun Exposed Lower leg 48 1.319 3.31
GTEx Small Intestine Terminal Ileum 10 2.169 3.47
GTEx Spleen 22 1.559 3.56
GTEx Stomach 27 1.857 3.46
GTEx Testis 41 1.300 3.25
GTEx Thyroid 54 1.350 3.24
GTEx Uterus 12 2.116 3.54
GTEx Vagina 13 2.047 3.62
GTEx Whole Blood 22 1.104 3.14
METSIM Adipose 42 0.911 2.91
NTR Blood 18 0.749 2.97
ROSMAP Brain Pre-frontal Cortex 57 1.298 3.28
YFS Blood 32 0.693 2.82
CommonMind Brain Pre-frontal Cortex 49 0.912 2.93
TCGA Breast Tumor 11 1.434 3.16
TCGA Breast Normal 31 0.737 2.68
TCGA Ovarian Tumor 27 0.924 2.82
TCGA Prostate Tumor 38 1.099 2.92