Hub : Traits :

Allergy or Eczema

1332 significantly associated models · 357 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 7686056 9637591 4 1 1.0e-17 1.3e-16 1.9e-02 92 RERE
2 1 15668276 16844848 1 1 2.9e-07 2.6e-05 2.3e-04 23 RP11-5P18.10
3 1 24372971 25768937 1 1 1.1e-07 2.8e-14 1.7e-09 37 CLIC4
4 1 35215224 36716820 1 1 2.1e-08 8.5e-11 3.6e-04 70 KIAA0319L
5 1 66585659 68152438 2 1 4.3e-09 7.6e-09 3.5e-01 97 MIER1
6 1 92277843 94120642 2 1 7.4e-09 1.7e-07 4.4e-02 85 EVI5
7 1 150679358 152712747 3 3 2.6e-11 7.9e-23 8.1e-22 5 LINGO4 POGZ S100A11
8 1 153225886 156572984 7 4 1.2e-12 2.5e-15 1.9e-05 71 C1orf43 DCST2 IL6R RIT1
9 1 160420036 161954448 6 1 5.4e-13 9.5e-14 4.1e-02 92 PPOX
10 1 166702558 168182443 1 1 2.6e-24 8.9e-26 1.0e+00 100 CD247
11 1 172311679 174328801 2 1 1.5e-16 4.4e-18 4.7e-03 89 TNFSF18
12 1 206194087 207458906 1 1 4.6e-09 5.3e-07 4.0e-01 97 RASSF5
13 2 27971195 29344127 1 1 3.7e-11 5.1e-09 8.1e-02 91 RP11-373D23.3
14 2 29976100 31563885 1 1 2.1e-09 5.6e-09 6.3e-01 99 LCLAT1
15 2 60466491 62123953 8 1 2.5e-11 1.2e-09 9.5e-03 82 AC010733.5
16 2 101922170 104027106 6 10 1.7e-31 1.1e-77 NaN NaN IL18R1 IL18RAP IL1R1 IL1R2 IL1RL2 SLC9A2
17 2 113192136 114472260 1 1 6.6e-10 3.1e-09 1.1e-02 81 IL36RN
18 2 134181178 135909462 1 1 7.5e-08 4.8e-05 8.5e-03 58 MGAT5
19 2 143154021 145209076 1 1 3.6e-08 4.5e-11 3.0e-06 50 ARHGAP15
20 2 187518260 189011680 1 1 7.4e-08 4.8e-08 1.0e+00 100 CALCRL
21 2 197134790 200117777 6 2 3.2e-21 6.8e-20 1.0e+00 100 PLCL1 SF3B1
22 2 241978472 243048760 9 4 3.0e-31 1.4e-32 1.8e-20 39 AC093642.3 AC093642.5 AC114730.7 D2HGDH
23 3 16154636 17814553 1 1 3.2e-07 3.3e-07 1.6e-02 78 PLCL2
24 3 32299549 33884651 2 1 1.1e-09 5.6e-15 2.5e-08 49 CCR4
25 3 120799666 122356172 3 1 6.0e-17 8.7e-17 1.0e+00 100 SLC15A2
26 3 140350567 142017527 2 1 5.4e-14 2.0e-14 1.0e+00 100 ZBTB38
27 3 195734915 197161849 4 2 4.0e-10 1.6e-08 2.9e-01 96 NRROS PIGX
28 4 38079294 39824758 7 9 6.4e-90 6.0e-105 0.0e+00 -212 FAM114A1 RP11-360F5.3 TLR1 TLR6
29 4 102736456 104627833 4 2 1.5e-11 1.4e-13 7.0e-02 94 NFKB1 SLC9B1
30 4 122377715 124935698 3 2 4.7e-37 3.6e-38 8.2e-01 100 KIAA1109 SPATA5
31 5 34920257 36938041 6 10 4.2e-21 2.6e-59 NaN NaN CAPSL IL7R NADKD1 SPEF2 UGT3A2
32 5 108927715 111770880 6 9 2.0e-51 2.9e-65 0.0e+00 -4320 CAMK4 SLC25A46 TSLP WDR36
33 5 130904163 132839137 6 2 1.9e-10 9.2e-14 1.7e-04 74 KIF3A PDLIM4
34 5 140062547 142230251 5 3 3.5e-11 6.4e-11 1.6e-01 95 AC008781.7 FCHSD1 NDFIP1
35 5 176040488 177426530 3 1 1.0e-10 1.2e-10 8.0e-02 93 RGS14
36 6 33745071 35362848 2 1 3.0e-09 1.7e-08 1.7e-01 94 PACSIN1
37 6 35625147 37050771 1 1 1.5e-07 1.7e-08 7.5e-03 78 ETV7
38 6 87336777 88803678 1 1 1.1e-07 2.0e-06 2.0e-01 93 C6orf164
39 6 89941356 91704536 1 1 7.3e-16 1.1e-17 3.3e-04 82 BACH2
40 6 107328319 108840870 1 1 2.3e-07 2.2e-06 2.7e-01 94 SCML4
41 6 134905567 136727603 3 1 5.7e-14 5.7e-16 1.6e-03 85 AHI1
42 7 27171588 28918565 1 2 1.9e-09 1.2e-20 2.8e-12 44 JAZF1
43 7 76058767 77744459 3 1 7.5e-13 3.1e-15 1.0e-03 83 GSAP
44 7 98358654 99820050 2 2 4.8e-08 1.0e-06 4.3e-01 97 PDAP1 ZKSCAN5
45 7 148285882 149691341 1 1 3.5e-07 8.0e-07 6.5e-02 86 RP4-800G7.2
46 7 149786096 151081791 1 1 5.0e-09 1.9e-06 8.8e-04 51 GIMAP2
47 8 128107136 129812343 1 1 1.9e-07 2.2e-15 1.3e-09 41 PVT1
48 9 4415824 7345304 7 5 4.1e-19 1.7e-27 2.5e-09 70 GLDC IGHEP2 KIAA1432 RANBP6 UHRF2
49 9 93170435 94567835 1 1 2.0e-07 1.4e-07 1.0e+00 100 RP11-305L7.1
50 9 122881960 124487495 5 1 4.0e-14 3.6e-14 1.0e+00 100 TRAF1
51 9 126321003 127872298 2 6 2.4e-11 3.5e-11 1.0e+00 100 NEK6 PSMB7
52 9 130439542 132601229 6 1 5.4e-13 3.2e-12 2.2e-01 97 ENDOG
53 10 5238196 7317647 3 3 2.0e-10 2.2e-28 4.6e-23 20 FBXO18 IL2RA PRKCQ
54 10 50896333 52285511 1 1 4.0e-09 3.2e-09 1.0e+00 100 NCOA4
55 10 103527782 105647095 12 1 3.5e-19 7.2e-17 2.3e-01 98 WBP1L
56 11 9636376 11227175 1 1 3.5e-07 9.7e-05 1.8e-04 8 AMPD3
57 11 54801549 55948667 1 1 8.7e-08 3.9e-03 1.2e-01 70 OR4A21P
58 11 64669105 68113724 15 3 1.8e-16 2.5e-23 2.6e-08 69 ACY3 EFEMP2 PACS1
59 11 75369353 77069746 4 3 3.8e-44 3.3e-71 7.3e-18 77 LRRC32 PRKRIR RP11-111M22.3
60 11 110721187 112435333 4 1 2.8e-13 7.9e-14 1.0e+00 100 SIK2
61 12 55389667 58303535 12 7 1.1e-23 3.9e-28 NaN NaN GLS2 RBMS2 RPS26 STAT6 SUOX WIBG
62 12 111522000 113517494 4 2 2.1e-09 1.2e-18 1.5e-05 76 ADAM1A TRAFD1
63 12 120449985 122429484 4 1 4.2e-17 1.2e-17 1.0e+00 100 SPPL3
64 12 122713991 124591385 9 1 2.8e-10 1.8e-09 6.1e-01 99 MPHOSPH9
65 13 40440805 41928314 1 1 1.2e-19 6.8e-14 1.0e-02 88 FOXO1
66 13 72661114 74288499 1 2 2.5e-10 1.7e-14 3.5e-06 64 PIBF1
67 14 34696729 36440325 4 1 8.9e-11 6.9e-10 8.5e-02 92 FAM177A1
68 14 102544860 104074810 1 1 3.7e-10 5.3e-12 2.9e-03 81 TRAF3
69 15 40360741 42749023 15 1 8.4e-18 7.4e-20 1.8e-03 88 RTF1
70 15 66662107 68183665 1 1 8.6e-17 1.0e-31 1.3e-16 50 SMAD3
71 15 74440419 76108550 3 1 2.0e-09 1.0e-09 9.1e-03 82 SCAMP2
72 15 89921477 92225560 8 2 6.8e-25 8.7e-22 2.0e-01 98 FES IQGAP1
73 16 10157081 12138068 7 11 1.1e-36 6.1e-45 NaN NaN CLEC16A DEXI FAM18A RMI2 RP11-396B14.2 RP11-876N24.5
74 16 26626758 29595483 21 2 1.2e-12 1.1e-10 2.7e-02 88 IL4R TUFM
75 17 1517914 2918626 1 1 3.1e-08 7.3e-09 2.5e-02 85 SRR
76 17 16718225 18325085 2 2 6.3e-09 4.4e-09 3.7e-01 98 PEMT TOM1L2
77 17 33941051 35644076 5 1 6.3e-09 1.3e-08 1.0e+00 100 ZNHIT3
78 17 36710513 39510218 18 7 3.2e-33 9.2e-32 NaN NaN GSDMA KRT222 MED24 ORMDL3 THRA
79 17 39559539 41675702 11 2 1.2e-12 3.0e-10 1.1e-01 94 NAGLU PTRF
80 17 42628193 43570226 1 1 1.0e-07 4.5e-10 2.2e-04 65 MAP3K14-AS1
81 18 47706580 49306115 2 1 2.0e-08 2.9e-09 1.0e+00 100 SMAD4
82 18 51100222 52540420 1 1 2.0e-10 8.7e-11 1.0e+00 100 POLI
83 20 44050342 45456440 1 1 8.9e-10 2.5e-07 1.5e-01 92 CD40
84 20 61522825 62912463 8 2 2.6e-13 1.8e-13 6.4e-03 86 STMN3 ZGPAT
85 21 39849553 41383143 2 1 1.0e-07 2.6e-07 1.0e+00 100 PSMG1
86 22 21075537 22685340 3 1 2.4e-09 3.1e-09 9.9e-02 92 CCDC116
87 22 40472399 42917154 12 2 8.6e-10 9.2e-10 1.0e+00 100 EP300 TEF

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Alzheimer’s Disease (including proxy) 1.14 1 0 0.0 0.00 1.0e+00 PPOX
Crohns Disease (2017) 3.71 27 18 54.5 -0.47 9.2e-03 AC010733.5 ARHGAP15 CCDC116 GSDMA IGHEP2 IL18RAP KIAA1109 KIF3A LRRC32 MED24 NAGLU NDFIP1 NFKB1 ORMDL3 PDLIM4 PLCL1 RIT1 RMI2 RP11-111M22.3 RP11-373D23.3 SF3B1 SMAD3 STMN3 TRAFD1 TUFM ZBTB38 ZGPAT
Irritable Bowel Disease (IBD) 3.56 25 21 63.6 -0.38 4.8e-02 AC010733.5 BACH2 CCDC116 FAM177A1 GSDMA IGHEP2 IL18RAP KIAA1109 LRRC32 MED24 NAGLU NDFIP1 ORMDL3 PDLIM4 PRKRIR RGS14 RIT1 RMI2 RP11-111M22.3 RP11-373D23.3 SMAD3 STMN3 TRAFD1 TUFM ZGPAT
Ulcerative Colitis (UC) 2.44 12 7 21.2 -0.50 9.6e-02 AC010733.5 GSDMA IGHEP2 KIAA1109 KRT222 LRRC32 MED24 ORMDL3 PRKRIR RGS14 SMAD3 STMN3
Reaction Time 1.04 1 0 0.0 0.00 1.0e+00 MIER1
Verbal and Numeric Reasoning (VNR) 1.09 4 2 6.1 -0.45 4.5e-01 PLCL2 SUOX TUFM ZNHIT3
Breast Cancer 1.90 9 5 15.2 0.71 6.0e-03 EFEMP2 EP300 FAM114A1 NAGLU PACS1 RIT1 TLR1 TLR6 ZBTB38
Ovarian Cancer 1.03 1 0 0.0 0.00 1.0e+00 PVT1
Prostate Cancer 3.07 4 2 6.1 0.96 3.8e-02 DCST2 NCOA4 STMN3 WBP1L
Age at First Birth 1.04 1 0 0.0 0.00 1.0e+00 TRAF3
Body Mass Index (BMI) (2010) 1.35 1 0 0.0 0.00 1.0e+00 TUFM
Crohns Disease (2012) 2.98 16 10 30.3 0.74 1.1e-03 AC010733.5 CCDC116 IGHEP2 IL18RAP LRRC32 NAGLU NDFIP1 PDLIM4 PLCL1 RIT1 RP11-373D23.3 SF3B1 SMAD3 STMN3 TUFM ZGPAT
HbA1C 1.09 2 0 0.0 0.00 1.0e+00 ADAM1A ZKSCAN5
HDL Cholesterol 1.51 4 1 3.0 -0.70 1.9e-01 CCDC116 GIMAP2 ORMDL3 PACSIN1
Lupus 2.07 6 3 9.1 0.08 8.7e-01 CCDC116 DEXI FAM18A ORMDL3 SCAMP2 SLC15A2
Primary Biliary Cirrhosis 2.85 6 4 12.1 -0.43 2.8e-01 DEXI NFKB1 ORMDL3 PLCL2 RMI2 SLC9B1
Rheumatoid Arthritis 1.76 2 1 3.0 0.00 1.0e+00 CD40 NRROS
Schizophrenia 1.37 8 1 3.0 0.64 8.6e-02 FES MPHOSPH9 PEMT PLCL1 PLCL2 RERE SF3B1 TOM1L2
Triglycerides 0.93 1 1 3.0 0.00 1.0e+00 RP11-373D23.3
Ulcerative Colitis 2.09 4 3 9.1 -0.51 4.9e-01 AC010733.5 IGHEP2 ORMDL3 STMN3
Blood Eosinophil Count 10.60 89 78 236.4 0.81 2.8e-27 AC093642.3 AC114730.7 ADAM1A BACH2 C6orf164 CAMK4 CAPSL CCDC116 CCR4 CD247 CLIC4 D2HGDH DCST2 DEXI EFEMP2 EP300 FAM114A1 FAM177A1 FAM18A FBXO18 FOXO1 GIMAP2 GLDC GLS2 GSDMA IGHEP2 IL18R1 IL18RAP IL1R1 IL1R2 IL1RL2 IL2RA IL4R IL7R KIAA1109 KIF3A KRT222 LCLAT1 LRRC32 MED24 MPHOSPH9 NADKD1 NDFIP1 NEK6 NRROS ORMDL3 PACS1 PDLIM4 PIBF1 PLCL2 POLI PPOX PRKCQ PRKRIR PSMB7 RANBP6 RASSF5 RERE RGS14 RMI2 RP11-305L7.1 RP11-396B14.2 RP11-876N24.5 RP4-800G7.2 RPS26 RTF1 SIK2 SLC25A46 SLC9A2 SLC9B1 SMAD3 SMAD4 SPATA5 SPEF2 SPPL3 STAT6 SUOX TEF THRA TLR6 TOM1L2 TRAF1 TRAFD1 TSLP UGT3A2 UHRF2 WDR36 WIBG ZNHIT3
Blood Platelet Count 2.06 40 33 100.0 0.14 3.7e-01 ADAM1A AHI1 C1orf43 CLIC4 EFEMP2 EP300 FOXO1 GLS2 IGHEP2 IL6R KIF3A MAP3K14-AS1 MPHOSPH9 NDFIP1 NEK6 ORMDL3 PACSIN1 PDAP1 PDLIM4 PSMB7 PSMG1 PTRF RBMS2 RMI2 SF3B1 SIK2 SLC15A2 SPPL3 SRR STAT6 STMN3 TEF TOM1L2 TRAF1 TRAF3 TRAFD1 TUFM WBP1L ZGPAT ZKSCAN5
Blood Red Count 1.30 34 24 72.7 -0.03 8.4e-01 ADAM1A AHI1 BACH2 CD40 CLIC4 EVI5 FAM114A1 FOXO1 GLS2 IGHEP2 MAP3K14-AS1 NDFIP1 NFKB1 ORMDL3 PLCL1 PLCL2 POLI RBMS2 RGS14 RP11-360F5.3 RPS26 RTF1 SCAMP2 SF3B1 SLC9B1 STMN3 SUOX TRAF3 TRAFD1 TUFM UHRF2 ZBTB38 ZGPAT ZKSCAN5
Blood White Count 7.38 51 30 90.9 0.27 4.5e-02 AC010733.5 ADAM1A AHI1 ARHGAP15 BACH2 C6orf164 CALCRL CAPSL CCDC116 DEXI EFEMP2 EVI5 FAM114A1 FES GSAP GSDMA IL1R2 IQGAP1 JAZF1 KIF3A MAP3K14-AS1 MED24 MIER1 NAGLU NDFIP1 ORMDL3 PACSIN1 PDLIM4 PEMT PIGX PLCL1 POLI PPOX PSMB7 RERE RGS14 RP11-305L7.1 RP11-373D23.3 RP11-396B14.2 RP11-876N24.5 RTF1 SCML4 SLC9B1 SRR THRA TOM1L2 TRAF1 TRAF3 TRAFD1 WBP1L ZGPAT
Heel T-Score 1.25 21 15 45.5 0.10 6.5e-01 CALCRL CCDC116 EP300 EVI5 IQGAP1 JAZF1 LCLAT1 MPHOSPH9 NEK6 OR4A21P PACS1 PSMB7 RBMS2 RERE RP4-800G7.2 SCAMP2 SLC15A2 SRR TEF WIBG ZBTB38
BMI 1.56 26 18 54.5 -0.51 3.9e-03 ARHGAP15 DCST2 EFEMP2 EVI5 FAM114A1 GSDMA NAGLU NEK6 OR4A21P PACS1 PACSIN1 PDAP1 PLCL1 PSMB7 PSMG1 RBMS2 RIT1 SRR STMN3 SUOX TLR1 TRAF3 TRAFD1 TUFM WIBG ZNHIT3
Height 1.58 35 26 78.8 -0.04 8.2e-01 ARHGAP15 C1orf43 CALCRL CCDC116 CCR4 DCST2 EVI5 FCHSD1 GLS2 IL18RAP IL7R IQGAP1 JAZF1 KIF3A MGAT5 MIER1 MPHOSPH9 NFKB1 PACSIN1 PDLIM4 POGZ PTRF RERE RGS14 RP11-373D23.3 RTF1 SPEF2 SPPL3 STAT6 THRA TLR6 TUFM UGT3A2 WBP1L ZBTB38
Waist Hip Ratio (WHR) 1.46 22 10 30.3 -0.51 1.1e-02 ADAM1A AMPD3 CALCRL CLEC16A DCST2 DEXI ENDOG GSAP JAZF1 MED24 MPHOSPH9 NAGLU PACSIN1 PLCL2 PTRF RP11-396B14.2 RP11-876N24.5 SIK2 TOM1L2 WBP1L ZBTB38 ZNHIT3
Systolic Blood Pressure 1.38 17 12 36.4 -0.24 3.3e-01 ADAM1A CLIC4 FES MAP3K14-AS1 NEK6 PSMB7 PTRF RERE RP11-111M22.3 RP11-373D23.3 RTF1 SCAMP2 SIK2 SLC15A2 SMAD3 TRAFD1 ZGPAT
Smoking Status 1.58 7 3 9.1 0.00 1.0e+00 ADAM1A FES PDAP1 PLCL2 RERE SUOX WBP1L
Cardiovascular Disease 1.41 12 6 18.2 -0.36 2.5e-01 ADAM1A CLIC4 FES KRT222 RERE RP11-111M22.3 RTF1 SCAMP2 SIK2 SUOX TRAFD1 ZGPAT
Hypothyroidism (self reported) 3.53 22 13 39.4 -0.04 8.6e-01 AC010733.5 ADAM1A AHI1 BACH2 CD247 DCST2 ENDOG FBXO18 NEK6 PSMB7 PTRF RBMS2 RERE RPS26 SLC15A2 SUOX TEF TLR1 TLR6 TRAF1 TRAFD1 WIBG
Respiratory disease 13.36 77 53 160.6 0.92 1.6e-39 AC008781.7 AC114730.7 AHI1 BACH2 C1orf43 CAMK4 CD247 D2HGDH DEXI EVI5 FAM114A1 FAM18A FBXO18 FOXO1 GLDC GSDMA IL18R1 IL18RAP IL1R1 IL1RL2 IL4R IL6R IL7R JAZF1 KIAA1109 KIAA1432 KIF3A KRT222 LINGO4 LRRC32 MAP3K14-AS1 MED24 MPHOSPH9 NAGLU NDFIP1 NRROS ORMDL3 PDLIM4 POGZ POLI PPOX PRKCQ PRKRIR PSMG1 PVT1 RANBP6 RBMS2 RERE RMI2 RP11-396B14.2 RP11-876N24.5 RPS26 RTF1 S100A11 SCML4 SIK2 SLC15A2 SLC25A46 SLC9A2 SMAD3 SPATA5 SPEF2 SPPL3 STAT6 STMN3 SUOX TEF THRA TLR1 TLR6 TNFSF18 TRAF1 TSLP UHRF2 WDR36 WIBG ZGPAT
Type 2 Diabetes (T2D) 1.10 1 0 0.0 0.00 1.0e+00 JAZF1
Lung FEV1/FVC ratio 1.78 30 14 42.4 -0.73 1.8e-06 AC010733.5 AMPD3 BACH2 C1orf43 CALCRL D2HGDH DCST2 DEXI EVI5 FOXO1 GIMAP2 GLDC IL18R1 IL1RL2 MED24 ORMDL3 PDLIM4 PRKCQ RERE RGS14 RP11-396B14.2 RP11-5P18.10 RPS26 SLC9A2 SMAD3 SUOX THRA TOM1L2 WIBG ZBTB38
Lung FVC 1.11 13 6 18.2 -0.53 4.9e-02 AHI1 FAM177A1 MPHOSPH9 ORMDL3 PACS1 PDLIM4 RBMS2 RTF1 SRR STMN3 SUOX ZBTB38 ZGPAT
Neuroticism 1.03 4 3 9.1 -0.68 3.2e-01 CD40 PLCL2 RERE TEF
Chronotype (morning person) 1.50 6 2 6.1 -0.74 3.4e-02 EVI5 GLS2 NEK6 PLCL1 PSMB7 SF3B1
Hair Pigment 0.27 14 9 27.3 0.50 5.0e-02 FAM114A1 FES JAZF1 KIAA1432 MPHOSPH9 NEK6 OR4A21P PSMB7 RIT1 RP11-373D23.3 RPS26 SUOX TRAF3 ZBTB38
Tanning 0.23 4 2 6.1 0.70 1.9e-01 DCST2 JAZF1 OR4A21P RP11-373D23.3
Hand grip strength (left) 0.93 3 2 6.1 0.00 1.0e+00 PDLIM4 WBP1L ZBTB38
Number of treatments/medications taken 1.65 2 0 0.0 0.00 1.0e+00 ADAM1A TRAFD1
Sensitivity / hurt feelings 0.97 1 0 0.0 0.00 1.0e+00 PLCL2
Frequency of depressed mood in last 2 weeks 1.22 1 0 0.0 0.00 1.0e+00 RERE
Relative age of first facial hair 1.03 3 1 3.0 0.00 1.0e+00 PSMG1 SPPL3 ZBTB38
Ever used hormone-replacement therapy (HRT) 1.30 2 0 0.0 0.00 1.0e+00 NEK6 PSMB7
Systolic blood pressure, automated reading 1.41 7 3 9.1 0.09 8.3e-01 FES PSMB7 RERE SLC15A2 SRR STMN3 ZGPAT
Angina 1.28 1 0 0.0 0.00 1.0e+00 FES
Medication: Metformin 1.20 1 0 0.0 0.00 1.0e+00 JAZF1
Impedance of leg (right) 1.62 17 10 30.3 -0.87 1.0e-06 ACY3 AMPD3 C6orf164 DCST2 EFEMP2 FCHSD1 JAZF1 NAGLU PACSIN1 PEMT PLCL1 RIT1 SF3B1 SRR SUOX TUFM WIBG
Leg fat-free mass (left) 1.72 22 12 36.4 0.43 3.9e-02 ARHGAP15 C6orf164 CCR4 DCST2 EFEMP2 FOXO1 MPHOSPH9 NAGLU PACSIN1 PDLIM4 PEMT PLCL1 RP11-373D23.3 SPPL3 SRR SUOX TRAF3 TRAFD1 TUFM WIBG ZBTB38 ZNHIT3
Trunk fat percentage 1.23 11 8 24.2 0.44 1.7e-01 ARHGAP15 PACS1 PACSIN1 RERE SF3B1 TEF TRAF3 TUFM ZBTB38 ZGPAT ZNHIT3
Hand grip strength (right) 0.83 3 2 6.1 0.00 1.0e+00 PDLIM4 WBP1L ZBTB38
Current tobacco smoking 1.39 1 0 0.0 0.00 1.0e+00 STMN3
Maternal smoking around birth 1.09 1 0 0.0 0.00 1.0e+00 ZNHIT3
Fed-up feelings 1.03 3 0 0.0 0.00 1.0e+00 CD40 PLCL2 TEF
Relative age voice broke 1.14 1 0 0.0 0.00 1.0e+00 C6orf164
Taking other prescription medications 2.66 5 0 0.0 -0.73 6.3e-02 ADAM1A D2HGDH DEXI ORMDL3 TRAFD1
Age when periods started (menarche) 1.18 3 1 3.0 0.00 1.0e+00 NFKB1 PSMG1 SUOX
Bilateral oophorectomy (both ovaries removed) 1.37 2 0 0.0 0.00 1.0e+00 CALCRL PSMB7
Heel bone mineral density (BMD) T-score, automated (left) 1.16 3 2 6.1 0.00 1.0e+00 EP300 IQGAP1 RERE
High blood pressure 1.33 9 2 6.1 0.36 3.4e-01 ADAM1A FES PDLIM4 POLI RERE RTF1 SIK2 SUOX TRAFD1
Hayfever, allergic rhinitis or eczema 21.68 138 95 287.9 -1.00 6.9e-191 AC008781.7 AC010733.5 AC093642.3 ACY3 ADAM1A AHI1 AMPD3 ARHGAP15 BACH2 C1orf43 C6orf164 CAMK4 CAPSL CCDC116 CCR4 CD247 CLEC16A CLIC4 D2HGDH DCST2 DEXI EFEMP2 ENDOG EP300 ETV7 EVI5 FAM114A1 FAM177A1 FAM18A FBXO18 FCHSD1 FOXO1 GIMAP2 GLDC GLS2 GSAP GSDMA IGHEP2 IL18R1 IL18RAP IL1R1 IL1RL2 IL2RA IL36RN IL4R IL6R IL7R IQGAP1 JAZF1 KIAA0319L KIAA1109 KIAA1432 KIF3A KRT222 LCLAT1 LINGO4 LRRC32 MAP3K14-AS1 MED24 MGAT5 MIER1 MPHOSPH9 NAGLU NCOA4 NDFIP1 NEK6 NFKB1 NRROS ORMDL3 PACS1 PACSIN1 PDAP1 PDLIM4 PEMT PIBF1 PIGX PLCL1 PLCL2 POLI PPOX PRKCQ PRKRIR PSMB7 PSMG1 PTRF RANBP6 RASSF5 RBMS2 RERE RGS14 RIT1 RMI2 RP11-111M22.3 RP11-305L7.1 RP11-360F5.3 RP11-373D23.3 RP11-396B14.2 RP11-5P18.10 RP11-876N24.5 RPS26 RTF1 S100A11 SCAMP2 SCML4 SF3B1 SIK2 SLC15A2 SLC25A46 SLC9A2 SLC9B1 SMAD3 SMAD4 SPATA5 SPEF2 SPPL3 SRR STAT6 STMN3 SUOX TEF THRA TLR1 TLR6 TNFSF18 TOM1L2 TRAF1 TRAF3 TRAFD1 TSLP TUFM UGT3A2 UHRF2 WBP1L WDR36 ZBTB38 ZGPAT ZKSCAN5 ZNHIT3
Medication: Atenolol 1.65 2 2 6.1 0.00 1.0e+00 FES TRAFD1
Medication: Levothyroxine sodium 2.83 9 6 18.2 0.16 6.6e-01 ADAM1A AHI1 BACH2 FBXO18 PTRF SLC15A2 SUOX TRAFD1 WIBG
Sitting height 1.45 13 9 27.3 -0.46 1.1e-01 CALCRL CCDC116 CCR4 EVI5 FAM114A1 MPHOSPH9 NEK6 NFKB1 PACSIN1 PDLIM4 RGS14 WBP1L ZBTB38
High blood pressure (mother) 1.25 1 1 3.0 0.00 1.0e+00 FES
Body mass index (BMI) 1.46 17 10 30.3 0.95 1.2e-09 ARHGAP15 DCST2 EFEMP2 EVI5 NAGLU PACS1 PACSIN1 PDAP1 PLCL1 PSMG1 RBMS2 SRR SUOX TRAF3 TUFM WIBG ZNHIT3
Impedance of leg (left) 1.60 19 10 30.3 -0.81 7.2e-06 ACY3 AMPD3 C6orf164 CCDC116 DCST2 EFEMP2 FCHSD1 JAZF1 NAGLU PACSIN1 PEMT PLCL1 RIT1 S100A11 SF3B1 SRR SUOX TUFM WIBG
Leg predicted mass (left) 1.72 22 12 36.4 0.43 3.9e-02 ARHGAP15 C6orf164 CCR4 DCST2 EFEMP2 FOXO1 MPHOSPH9 NAGLU PACSIN1 PDLIM4 PEMT PLCL1 RP11-373D23.3 SPPL3 SRR SUOX TRAF3 TRAFD1 TUFM WIBG ZBTB38 ZNHIT3
Trunk fat mass 1.37 9 7 21.2 0.57 1.1e-01 ARHGAP15 NAGLU PACS1 PACSIN1 RERE TRAF3 TUFM ZBTB38 ZNHIT3
Waist circumference 1.52 11 7 21.2 0.78 4.5e-03 CALCRL FOXO1 NAGLU PACSIN1 PDAP1 RP11-373D23.3 SUOX TRAF3 TUFM ZBTB38 ZNHIT3
Past tobacco smoking 1.27 5 1 3.0 -0.55 3.4e-01 ADAM1A PDAP1 PSMG1 SUOX WBP1L
Hearing difficulty/problems with background noise 1.29 1 0 0.0 0.00 1.0e+00 WBP1L
Hair/balding pattern: Pattern 2 1.07 1 0 0.0 0.00 1.0e+00 CLIC4
Forced vital capacity (FVC) 1.01 9 5 15.2 0.35 3.5e-01 AHI1 CCR4 LINGO4 PACSIN1 PEMT STMN3 WBP1L ZBTB38 ZGPAT
Heel bone mineral density (BMD) T-score, automated (right) 1.19 4 2 6.1 0.37 6.3e-01 IQGAP1 NEK6 RERE ZBTB38
Qualifications: None of the above 1.25 5 3 9.1 0.27 6.1e-01 MPHOSPH9 PLCL2 SUOX TUFM ZNHIT3
Allergy 21.34 124 97 293.9 0.99 1.9e-124 AC008781.7 AC010733.5 AC093642.3 AHI1 BACH2 C1orf43 C6orf164 CAMK4 CAPSL CCDC116 CCR4 CD247 CLEC16A CLIC4 D2HGDH DEXI EFEMP2 ENDOG EP300 ETV7 EVI5 FAM114A1 FAM177A1 FAM18A FBXO18 FCHSD1 FOXO1 GIMAP2 GLDC GLS2 GSAP GSDMA IGHEP2 IL18R1 IL18RAP IL1R1 IL1R2 IL1RL2 IL2RA IL36RN IL4R IL6R IL7R IQGAP1 JAZF1 KIAA1109 KIAA1432 KIF3A KRT222 LCLAT1 LINGO4 LRRC32 MAP3K14-AS1 MED24 MGAT5 MIER1 MPHOSPH9 NADKD1 NAGLU NDFIP1 NEK6 NFKB1 NRROS ORMDL3 PDLIM4 PEMT PIGX PLCL1 POGZ POLI PPOX PRKCQ PRKRIR PSMB7 PSMG1 PTRF PVT1 RANBP6 RASSF5 RBMS2 RERE RGS14 RMI2 RP11-111M22.3 RP11-360F5.3 RP11-373D23.3 RP11-396B14.2 RP11-876N24.5 RPS26 RTF1 S100A11 SCML4 SF3B1 SIK2 SLC15A2 SLC25A46 SLC9A2 SLC9B1 SMAD3 SMAD4 SPATA5 SPEF2 SPPL3 STAT6 STMN3 SUOX TEF THRA TLR1 TLR6 TNFSF18 TRAF1 TRAF3 TRAFD1 TSLP TUFM UGT3A2 UHRF2 WBP1L WDR36 WIBG ZBTB38 ZGPAT ZKSCAN5
Diabetes (self-reported) 1.09 2 0 0.0 0.00 1.0e+00 JAZF1 NAGLU
Hayfever/allergic rhinitis (self-reported) 10.02 37 21 63.6 -0.97 1.7e-31 BACH2 CAMK4 CD247 D2HGDH DEXI FAM114A1 FAM18A GLDC GLS2 IL18R1 IL18RAP IL1RL2 IL7R IQGAP1 KIAA1109 KRT222 LRRC32 ORMDL3 PDAP1 PEMT PLCL1 PPOX RANBP6 RP11-396B14.2 RP11-876N24.5 SLC25A46 SLC9A2 SMAD3 SPATA5 SUOX TLR1 TLR6 TNFSF18 TSLP TUFM WDR36 ZKSCAN5
Medication: Ramipril 1.23 1 0 0.0 0.00 1.0e+00 ADAM1A
Fluid intelligence score 1.16 5 0 0.0 -0.12 8.5e-01 MPHOSPH9 PLCL2 SUOX TUFM ZNHIT3
Illnesses of siblings 1.34 2 0 0.0 0.00 1.0e+00 ADAM1A FES
Neuroticism score 0.93 4 1 3.0 0.66 3.4e-01 CD40 PLCL2 RERE TEF
Weight 1.69 17 11 33.3 0.55 1.9e-02 ARHGAP15 DCST2 EFEMP2 FAM114A1 FOXO1 NAGLU PACS1 PACSIN1 PLCL1 RP11-373D23.3 SUOX TRAF3 TRAFD1 TUFM WIBG ZBTB38 ZNHIT3
Impedance of arm (right) 2.02 23 16 48.5 -0.58 9.4e-04 AMPD3 C6orf164 DCST2 EFEMP2 EP300 FCHSD1 GSDMA JAZF1 LCLAT1 LRRC32 MED24 NEK6 ORMDL3 PACSIN1 PLCL1 PSMB7 SF3B1 SLC9B1 SMAD3 SUOX TEF TRAFD1 WIBG
Arm fat percentage (right) 1.19 10 5 15.2 0.73 1.7e-02 ARHGAP15 NAGLU PACSIN1 PDAP1 RBMS2 RERE SUOX TRAF3 TUFM ZNHIT3
Trunk fat-free mass 1.81 23 13 39.4 0.20 3.3e-01 AMPD3 ARHGAP15 DCST2 EFEMP2 GLS2 MPHOSPH9 NEK6 PACSIN1 PDLIM4 PEMT PLCL1 PSMB7 RP11-373D23.3 SF3B1 SPEF2 SPPL3 SUOX TRAF3 TRAFD1 TUFM WBP1L WIBG ZBTB38
Hip circumference 1.60 16 5 15.2 0.35 1.9e-01 DCST2 EFEMP2 FAM114A1 FOXO1 GSDMA PACS1 PACSIN1 PSMG1 RP11-373D23.3 STMN3 SUOX TRAF3 TRAFD1 TUFM ZBTB38 ZNHIT3
Father's age at death 1.48 1 0 0.0 0.00 1.0e+00 FES
Worrier / anxious feelings 1.05 2 0 0.0 0.00 1.0e+00 OR4A21P PLCL2
Hair/balding pattern: Pattern 3 0.88 1 0 0.0 0.00 1.0e+00 CLIC4
Number of live births 1.14 2 0 0.0 0.00 1.0e+00 SLC9B1 TUFM
Forced expiratory volume in 1-second (FEV1) 1.10 7 3 9.1 0.59 1.2e-01 AHI1 LINGO4 PACSIN1 SUOX WIBG ZBTB38 ZGPAT
Pulse rate 1.08 1 1 3.0 0.00 1.0e+00 ZBTB38
Qualifications: A levels/AS levels or equivalent 1.02 2 1 3.0 0.00 1.0e+00 MPHOSPH9 SUOX
Mouth/teeth dental problems: Dentures 1.18 1 0 0.0 0.00 1.0e+00 PPOX
Asthma 13.13 62 42 127.3 -0.92 3.1e-33 AHI1 BACH2 C1orf43 CAMK4 CD247 D2HGDH DEXI FAM114A1 FAM18A GLDC GSDMA IL18R1 IL18RAP IL1R1 IL1RL2 IL4R IL7R JAZF1 KIAA1109 KIAA1432 KIF3A KRT222 LINGO4 LRRC32 MED24 NAGLU NDFIP1 NRROS ORMDL3 PDLIM4 POLI PPOX PRKCQ PRKRIR RANBP6 RBMS2 RERE RMI2 RP11-396B14.2 RP11-876N24.5 RPS26 RTF1 S100A11 SCML4 SIK2 SLC25A46 SLC9A2 SMAD3 SPPL3 STAT6 STMN3 SUOX TEF THRA TLR1 TLR6 TNFSF18 TSLP UHRF2 WDR36 WIBG ZGPAT
Medication: Ibuprofen (e.g. Nurofen) 0.94 1 0 0.0 0.00 1.0e+00 STAT6
Medication: Cholesterol lowering 1.06 1 1 3.0 0.00 1.0e+00 FES
Depression (self-reported) 0.97 1 0 0.0 0.00 1.0e+00 RERE
Prospective memory result 1.23 1 0 0.0 0.00 1.0e+00 PLCL2
Illnesses of mother 1.15 1 1 3.0 0.00 1.0e+00 FES
Forced expiratory volume in 1-second (FEV1), Best measure 1.06 5 3 9.1 0.62 1.9e-01 LINGO4 PACSIN1 SUOX ZBTB38 ZGPAT
Pulse wave Arterial Stiffness index 1.36 1 1 3.0 0.00 1.0e+00 ADAM1A
Impedance of arm (left) 1.98 23 14 42.4 -0.59 1.1e-03 AMPD3 C6orf164 DCST2 EFEMP2 EP300 FCHSD1 JAZF1 LRRC32 MED24 NEK6 ORMDL3 PACSIN1 PLCL1 PSMB7 RP11-373D23.3 RPS26 SF3B1 SLC9B1 SMAD3 SUOX TEF TRAFD1 WIBG
Arm fat mass (right) 1.41 13 8 24.2 0.77 2.2e-03 ARHGAP15 FOXO1 NAGLU PACS1 PACSIN1 PDAP1 RBMS2 SUOX TRAF3 TUFM WIBG ZBTB38 ZNHIT3
Trunk predicted mass 1.83 23 14 42.4 0.20 3.4e-01 AMPD3 ARHGAP15 DCST2 EFEMP2 GLS2 MPHOSPH9 NEK6 PACSIN1 PDLIM4 PEMT PLCL1 PSMB7 RP11-373D23.3 SF3B1 SPEF2 SPPL3 SUOX TRAF3 TRAFD1 TUFM WBP1L WIBG ZBTB38
Standing height 1.54 19 14 42.4 -0.22 3.7e-01 CCR4 DCST2 EVI5 FCHSD1 GLS2 IQGAP1 MGAT5 MIER1 MPHOSPH9 PACSIN1 PDLIM4 RGS14 RP11-360F5.3 RP11-373D23.3 RTF1 SPPL3 TUFM WBP1L ZBTB38
Breastfed as a baby 1.53 3 0 0.0 0.00 1.0e+00 MPHOSPH9 NEK6 PSMB7
Tense / 'highly strung' 1.02 2 1 3.0 0.00 1.0e+00 RERE TEF
Hair/balding pattern: Pattern 4 1.30 7 4 12.1 0.12 8.0e-01 CLIC4 IQGAP1 MAP3K14-AS1 POLI RP11-5P18.10 S100A11 ZBTB38
Birth weight of first child 1.64 5 3 9.1 -0.65 2.3e-01 FES SUOX TRAFD1 ZBTB38 ZKSCAN5
Qualifications: O levels/GCSEs or equivalent 1.17 2 1 3.0 0.00 1.0e+00 MPHOSPH9 PLCL2
Headache pain in last month 1.40 2 0 0.0 0.00 1.0e+00 SUOX WIBG
Medication for cholesterol, blood pressure or diabetes 1.34 2 2 6.1 0.00 1.0e+00 FES SIK2
Gout (self-reported) 1.26 1 0 0.0 0.00 1.0e+00 DCST2
Hypothyroidism/myxoedema (self-reported) 3.12 16 8 24.2 -0.05 8.3e-01 ADAM1A AHI1 BACH2 CD247 FBXO18 NEK6 PSMB7 PTRF RBMS2 RERE RPS26 SLC15A2 SUOX TEF TRAFD1 WIBG
Medication: Amlodipine 1.13 1 0 0.0 0.00 1.0e+00 FES
Medication: Ventolin 100micrograms inhaler 6.08 17 7 21.2 -0.95 3.0e-10 CD247 D2HGDH FOXO1 GLDC IL18R1 IL18RAP IL1RL2 KIAA1109 LRRC32 NDFIP1 ORMDL3 PRKRIR SLC9A2 SMAD3 SUOX THRA TLR1
Birth weight 1.63 10 4 12.1 -0.30 4.0e-01 ADAM1A DCST2 FES MIER1 NFKB1 RIT1 RPS26 SIK2 TRAF1 TRAFD1
High blood pressure (siblings) 1.20 1 1 3.0 0.00 1.0e+00 FES
Forced vital capacity (FVC), Best measure 0.93 9 2 6.1 0.35 3.5e-01 AHI1 CCR4 LINGO4 PACSIN1 STMN3 SUOX WBP1L ZBTB38 ZGPAT
Body fat percentage 1.24 12 6 18.2 0.35 2.7e-01 ARHGAP15 NAGLU PACS1 PACSIN1 RERE STMN3 TEF TRAF3 TUFM ZBTB38 ZGPAT ZNHIT3
Leg fat percentage (right) 1.31 12 6 18.2 0.36 2.5e-01 ARHGAP15 KRT222 NRROS PACS1 PACSIN1 RBMS2 RERE STMN3 TRAF3 TUFM ZGPAT ZNHIT3
Arm fat-free mass (right) 1.94 20 16 48.5 0.31 1.4e-01 AMPD3 ARHGAP15 DCST2 EFEMP2 MPHOSPH9 NEK6 PACS1 PACSIN1 PDLIM4 PLCL1 PSMB7 RP11-373D23.3 SF3B1 SUOX TRAF3 TRAFD1 TUFM WBP1L WIBG ZBTB38
Comparative body size at age 10 1.25 7 1 3.0 0.97 4.0e-04 EFEMP2 MIER1 PLCL1 RIT1 SRR TUFM ZNHIT3
Wheeze or whistling in the chest in last year 5.35 29 14 42.4 -0.96 4.6e-21 BACH2 C1orf43 CD247 D2HGDH DEXI GLDC GSDMA IL18R1 IL1R1 IL1RL2 KIAA1109 LRRC32 MED24 NRROS ORMDL3 PRKRIR RERE RP11-396B14.2 RP11-876N24.5 SIK2 SLC25A46 SLC9A2 SMAD3 STAT6 STMN3 THRA TSLP WDR36 ZGPAT
Age at first live birth 1.17 1 0 0.0 0.00 1.0e+00 SUOX
Pulse wave peak to peak time 1.34 1 1 3.0 0.00 1.0e+00 ADAM1A
Shortness of breath walking on level ground 1.22 1 0 0.0 0.00 1.0e+00 LRRC32
Qualifications: College or University degree 1.23 7 3 9.1 -0.78 2.1e-02 CD40 MPHOSPH9 PACS1 RPS26 SUOX TUFM WIBG
Medication for pain relief, constipation, heartburn 1.17 1 0 0.0 0.00 1.0e+00 MPHOSPH9
Neck or shoulder pain in last month 1.49 3 0 0.0 0.00 1.0e+00 NEK6 PSMB7 SUOX
Medication: Blood pressure 1.45 3 2 6.1 0.00 1.0e+00 ADAM1A FES SIK2
Angina (self-reported) 1.22 1 0 0.0 0.00 1.0e+00 FES
Migraine (self-reported) 1.22 1 1 3.0 0.00 1.0e+00 STAT6
Medication: Allopurinol 1.16 1 0 0.0 0.00 1.0e+00 DCST2
Medication: Seretide 50 evohaler 2.83 2 0 0.0 0.00 1.0e+00 D2HGDH PDLIM4
Mean time to correctly identify matches 0.90 1 0 0.0 0.00 1.0e+00 MIER1
Whole body fat mass 1.40 14 7 21.2 0.39 1.7e-01 ARHGAP15 EFEMP2 NAGLU PACS1 PACSIN1 PDAP1 RERE STMN3 SUOX TRAF3 TUFM WIBG ZBTB38 ZNHIT3
Leg fat mass (right) 1.50 16 9 27.3 0.54 3.0e-02 ARHGAP15 EFEMP2 NAGLU PACS1 PACSIN1 PDAP1 RBMS2 RERE RP11-373D23.3 STMN3 SUOX TRAF3 TUFM WIBG ZBTB38 ZNHIT3
Arm predicted mass (right) 1.96 18 16 48.5 0.27 2.2e-01 ARHGAP15 DCST2 EFEMP2 MPHOSPH9 NEK6 PACSIN1 PDLIM4 PLCL1 PSMB7 RP11-373D23.3 SF3B1 SUOX TRAF3 TRAFD1 TUFM WBP1L WIBG ZBTB38
Pulse rate, automated reading 1.21 8 4 12.1 -0.34 4.1e-01 CALCRL PACSIN1 PDAP1 SIK2 SUOX TOM1L2 ZBTB38 ZKSCAN5
Alcohol intake frequency. 1.34 4 1 3.0 0.90 9.6e-02 NAGLU RP11-360F5.3 SUOX TUFM
Comparative height size at age 10 1.34 13 6 18.2 -0.41 1.6e-01 C1orf43 CCR4 DCST2 EVI5 IQGAP1 MIER1 MPHOSPH9 PACSIN1 PDLIM4 TRAFD1 TUFM WBP1L ZBTB38
Suffer from 'nerves' 0.88 1 0 0.0 0.00 1.0e+00 RERE
Overall health rating 1.09 3 1 3.0 0.00 1.0e+00 PLCL1 SF3B1 TOM1L2
Supplements: Vitamin C 0.93 1 0 0.0 0.00 1.0e+00 ORMDL3
Knee pain experienced in last month 1.36 2 0 0.0 0.00 1.0e+00 DEXI RP11-396B14.2
Hypertension (Self-reported) 1.40 11 2 6.1 0.43 1.9e-01 ADAM1A CLIC4 FES PDLIM4 POLI RERE RTF1 SCAMP2 SIK2 SUOX TRAFD1
Illnesses of father: Heart disease 1.46 3 1 3.0 0.00 1.0e+00 FES SIK2 SMAD3
Forced expiratory volume in 1-second (FEV1), predicted 1.33 4 2 6.1 -0.52 4.8e-01 MGAT5 PACSIN1 WBP1L ZBTB38
Whole body fat-free mass 1.82 23 15 45.5 0.26 2.1e-01 AMPD3 ARHGAP15 DCST2 EFEMP2 GLS2 MPHOSPH9 NEK6 PACSIN1 PDLIM4 PEMT PLCL1 PSMB7 RP11-373D23.3 SF3B1 SPEF2 SPPL3 SUOX TRAF3 TRAFD1 TUFM WBP1L WIBG ZBTB38
Leg fat-free mass (right) 1.72 19 11 33.3 0.44 5.5e-02 ARHGAP15 C6orf164 DCST2 EFEMP2 MPHOSPH9 NAGLU PACSIN1 PDLIM4 PEMT PLCL1 RP11-360F5.3 RP11-373D23.3 SPPL3 SUOX TRAF3 TRAFD1 TUFM WIBG ZBTB38
Arm fat percentage (left) 1.19 9 6 18.2 0.66 5.4e-02 ARHGAP15 NAGLU PACSIN1 PDAP1 RERE TEF TRAF3 TUFM ZNHIT3
Mood swings 1.17 3 1 3.0 0.00 1.0e+00 CD40 PLCL2 TEF
Loneliness, isolation 1.04 1 0 0.0 0.00 1.0e+00 RERE
Long-standing illness, disability or infirmity 1.60 1 0 0.0 0.00 1.0e+00 ZGPAT
Ever had bowel cancer screening 1.23 1 0 0.0 0.00 1.0e+00 SIK2
Diabetes diagnosed by doctor 1.11 2 0 0.0 0.00 1.0e+00 JAZF1 NAGLU
Qualifications: nursing, teaching 0.95 1 0 0.0 0.00 1.0e+00 MPHOSPH9
Mouth/teeth dental problems: Mouth ulcers 2.16 1 0 0.0 0.00 1.0e+00 NFKB1
Medication for cholesterol 1.08 1 0 0.0 0.00 1.0e+00 TRAFD1
Mineral and other dietary supplements 1.19 1 0 0.0 0.00 1.0e+00 PDAP1
Asthma (self-reported) 13.03 63 44 133.3 -0.92 1.7e-33 AHI1 BACH2 C1orf43 CAMK4 CD247 D2HGDH DEXI FAM114A1 FAM18A GLDC GSDMA IL18R1 IL18RAP IL1R1 IL1RL2 IL4R IL7R JAZF1 KIAA1109 KIAA1432 KIF3A KRT222 LINGO4 LRRC32 MED24 NAGLU NDFIP1 NRROS ORMDL3 PDLIM4 POLI PPOX PRKCQ PRKRIR RANBP6 RBMS2 RERE RMI2 RP11-396B14.2 RP11-876N24.5 RPS26 RTF1 S100A11 SCML4 SIK2 SLC25A46 SLC9A2 SMAD3 SPATA5 SPPL3 STAT6 STMN3 SUOX TEF THRA TLR1 TLR6 TNFSF18 TSLP UHRF2 WDR36 WIBG ZGPAT
Medication: Aspirin 1.34 2 0 0.0 0.00 1.0e+00 FES SIK2
Illnesses of father: None of the above (group 1) 1.36 1 0 0.0 0.00 1.0e+00 FES
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.39 2 1 3.0 0.00 1.0e+00 ORMDL3 ZGPAT
Whole body water mass 1.82 22 15 45.5 0.21 3.1e-01 AMPD3 ARHGAP15 DCST2 EFEMP2 GLS2 MPHOSPH9 NEK6 PACSIN1 PDLIM4 PEMT PLCL1 PSMB7 RP11-373D23.3 SF3B1 SPPL3 SUOX TRAF3 TRAFD1 TUFM WBP1L WIBG ZBTB38
Leg predicted mass (right) 1.73 19 11 33.3 0.43 5.6e-02 ARHGAP15 C6orf164 DCST2 EFEMP2 MPHOSPH9 NAGLU PACSIN1 PDLIM4 PEMT PLCL1 RP11-360F5.3 RP11-373D23.3 SPPL3 SUOX TRAF3 TRAFD1 TUFM WIBG ZBTB38
Arm fat mass (left) 1.43 16 8 24.2 0.68 3.6e-03 ARHGAP15 DCST2 EFEMP2 FOXO1 NAGLU PACS1 PACSIN1 PDAP1 RBMS2 RERE SUOX TRAF3 TUFM WIBG ZBTB38 ZNHIT3
Number of self-reported non-cancer illnesses 2.72 9 2 6.1 -0.84 2.5e-03 IL1RL2 LRRC32 ORMDL3 PDLIM4 RGS14 RP11-396B14.2 STMN3 TRAFD1 ZGPAT
Miserableness 1.18 1 0 0.0 0.00 1.0e+00 ORMDL3
Medication: Blood pressure 1.32 5 1 3.0 0.24 7.0e-01 FES PDLIM4 SIK2 TRAFD1 ZGPAT
Supplements: Fish oil (including cod liver oil) 1.11 1 0 0.0 0.00 1.0e+00 PDAP1
Medication: Bendroflumethiazide 1.05 1 0 0.0 0.00 1.0e+00 FES
Illnesses of father: High blood pressure 1.32 1 1 3.0 0.00 1.0e+00 FES
Ever smoked 1.25 3 1 3.0 0.00 1.0e+00 PDAP1 PSMG1 WBP1L
Basal metabolic rate 1.81 20 13 39.4 0.42 5.6e-02 ARHGAP15 DCST2 EFEMP2 FOXO1 MPHOSPH9 NEK6 PACSIN1 PDLIM4 PEMT PLCL1 RP11-373D23.3 SF3B1 SUOX TRAF3 TRAFD1 TUFM WBP1L WIBG ZBTB38 ZNHIT3
Leg fat percentage (left) 1.33 12 7 21.2 0.32 3.1e-01 ARHGAP15 KRT222 MPHOSPH9 PACS1 PACSIN1 PDAP1 RERE STMN3 TRAF3 TUFM ZGPAT ZNHIT3
Arm fat-free mass (left) 1.94 19 16 48.5 0.27 2.1e-01 ARHGAP15 DCST2 EFEMP2 MPHOSPH9 NEK6 PACSIN1 PDLIM4 PLCL1 PSMB7 RP11-373D23.3 SF3B1 SUOX TRAF3 TRAFD1 TUFM WBP1L WIBG ZBTB38 ZNHIT3
Number of operations (self-reported) 1.65 3 0 0.0 0.60 4.0e-01 DEXI NEK6 PSMB7
Irritability 1.10 1 0 0.0 0.00 1.0e+00 TEF
Ever had prostate specific antigen (PSA) test 1.46 1 0 0.0 0.00 1.0e+00 ZBTB38
Diastolic blood pressure, automated reading 1.56 12 7 21.2 0.17 6.1e-01 ADAM1A CLIC4 FES MPHOSPH9 RERE SCAMP2 SLC15A2 SRR STMN3 SUOX TRAFD1 ZGPAT
Unable to work because of sickness or disability 0.94 1 0 0.0 0.00 1.0e+00 SF3B1
Myopia 1.29 2 0 0.0 0.00 1.0e+00 ORMDL3 STAT6
Vascular/heart problems diagnosed by doctor 1.44 9 3 9.1 -0.37 3.3e-01 ADAM1A FES PDLIM4 RERE RTF1 SCAMP2 SIK2 SUOX TRAFD1
Cholesterol lowering medication 1.04 1 0 0.0 0.00 1.0e+00 CALCRL
Pain experienced in last month 1.52 1 1 3.0 0.00 1.0e+00 SUOX
Impedance of whole body 1.80 19 15 45.5 -0.70 2.0e-04 AMPD3 C6orf164 DCST2 EFEMP2 EP300 FCHSD1 JAZF1 MED24 NEK6 PACSIN1 PLCL1 PSMB7 RPS26 SF3B1 SRR SUOX TEF WIBG ZNHIT3
Leg fat mass (left) 1.52 16 9 27.3 0.54 2.9e-02 ARHGAP15 EFEMP2 NAGLU PACS1 PACSIN1 PDAP1 RBMS2 RERE RP11-373D23.3 STMN3 SUOX TRAF3 TUFM WIBG ZBTB38 ZNHIT3
Arm predicted mass (left) 1.97 20 16 48.5 0.32 1.3e-01 ARHGAP15 DCST2 EFEMP2 FOXO1 MPHOSPH9 NEK6 PACSIN1 PDLIM4 PLCL1 PSMB7 RP11-373D23.3 SF3B1 SUOX TRAF3 TRAFD1 TUFM WBP1L WIBG ZBTB38 ZNHIT3

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 36 1.031 2.62
GTEx Adipose Visceral Omentum 20 0.982 2.62
GTEx Adrenal Gland 13 0.892 2.49
GTEx Artery Aorta 35 1.176 2.59
GTEx Artery Coronary 9 0.760 2.53
GTEx Artery Tibial 42 1.118 2.63
GTEx Brain Caudate basal ganglia 9 0.978 2.38
GTEx Brain Cerebellar Hemisphere 20 1.343 2.59
GTEx Brain Cerebellum 22 1.109 2.53
GTEx Brain Cortex 17 1.644 2.73
GTEx Brain Frontal Cortex BA9 10 1.081 2.66
GTEx Brain Hippocampus 5 0.952 2.18
GTEx Brain Hypothalamus 9 1.523 2.61
GTEx Brain Nucleus accumbens basal ganglia 16 1.848 2.76
GTEx Brain Putamen basal ganglia 11 1.763 2.80
GTEx Breast Mammary Tissue 27 1.367 2.89
GTEx Breast Mammary Tissue (Male) 17 1.425 2.74
GTEx Breast Mammary Tissue (Female) 19 1.155 2.82
GTEx Cells EBV-transformed lymphocytes 17 1.196 2.43
GTEx Cells Transformed fibroblasts 54 1.286 2.76
GTEx Colon Sigmoid 17 1.162 2.67
GTEx Colon Transverse 24 1.162 2.66
GTEx Esophagus Gastroesophageal Junction 21 1.453 2.56
GTEx Esophagus Mucosa 39 1.174 2.80
GTEx Esophagus Muscularis 45 1.392 2.68
GTEx Heart Atrial Appendage 13 0.823 2.48
GTEx Heart Left Ventricle 11 0.718 2.27
GTEx Liver 9 1.255 2.58
GTEx Lung 32 1.114 2.53
GTEx Muscle Skeletal 26 0.899 2.54
GTEx Nerve Tibial 49 1.133 2.56
GTEx Ovary 11 1.210 2.40
GTEx Pancreas 25 1.531 2.79
GTEx Pituitary 15 1.344 2.58
GTEx Prostate 9 1.079 2.47
GTEx Skin Not Sun Exposed Suprapubic 29 1.179 2.69
GTEx Skin Sun Exposed Lower leg 48 1.320 2.62
GTEx Small Intestine Terminal Ileum 5 1.082 2.33
GTEx Spleen 15 1.063 2.68
GTEx Stomach 16 1.100 2.45
GTEx Testis 38 1.204 2.81
GTEx Thyroid 53 1.326 2.70
GTEx Uterus 7 1.235 2.42
GTEx Vagina 4 0.630 2.34
GTEx Whole Blood 22 1.106 2.81
METSIM Adipose 51 1.107 2.67
NTR Blood 34 1.415 2.89
ROSMAP Brain Pre-frontal Cortex 41 0.934 2.62
YFS Blood 52 1.127 2.92
CommonMind Brain Pre-frontal Cortex 58 1.079 2.58
TCGA Breast Tumor 13 1.697 3.03
TCGA Breast Normal 31 0.737 2.39
TCGA Ovarian Tumor 19 0.650 2.07
TCGA Prostate Tumor 42 1.215 2.68