Hub : Traits :

Forced expiratory volume in 1-second (FEV1), Best measure

1604 significantly associated models · 408 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 16273995 18027554 6 1 1.0e-09 2.1e-09 3.2e-01 97 MST1P2
2 1 25475418 27595862 7 2 1.1e-13 3.5e-12 8.8e-01 100 DHDDS TRIM63
3 1 37307281 39147240 4 2 1.6e-08 4.9e-08 1.0e+00 100 DNALI1 SF3A3
4 1 40748755 42406344 2 1 5.4e-15 6.5e-15 5.7e-03 87 SCMH1
5 1 50735395 52135979 1 1 2.8e-07 3.7e-08 3.2e-02 85 CDKN2C
6 1 67814420 69212053 1 1 2.8e-08 4.8e-07 2.6e-01 95 DIRAS3
7 1 77655651 79300939 3 1 2.4e-09 1.1e-08 4.5e-02 88 GIPC2
8 1 111034818 112443281 1 1 2.6e-07 5.6e-08 4.7e-02 87 DENND2D
9 1 149854324 151659071 7 1 1.4e-09 1.6e-10 2.9e-03 78 CTSS
10 1 178129899 179534540 1 1 7.4e-09 1.3e-10 4.8e-03 81 ANGPTL1
11 1 180186713 181614143 1 1 2.4e-07 1.5e-07 1.0e+00 100 KIAA1614
12 1 183325796 184739300 1 1 2.1e-07 2.8e-06 4.0e-01 97 TSEN15
13 1 203785948 205241659 1 1 3.7e-09 7.9e-08 1.1e-01 91 MDM4
14 1 227222963 228614123 1 1 7.8e-09 4.7e-07 1.3e-02 76 JMJD4
15 2 23453834 25889403 5 2 1.5e-11 9.1e-13 3.5e-02 91 ADCY3 UBXN2A
16 2 35884899 37567226 4 1 2.6e-08 6.9e-08 4.2e-02 86 RP11-78I14.1
17 2 55401562 56843605 1 2 4.7e-26 1.5e-30 2.2e-02 96 EFEMP1
18 2 69829251 71228388 1 1 1.7e-07 4.1e-05 5.9e-01 98 FAM136A
19 2 100029106 101629737 2 1 8.7e-09 3.2e-10 1.1e-02 83 LONRF2
20 2 112213244 113641631 1 1 2.2e-07 1.1e-05 4.1e-01 96 FBLN7
21 2 135898023 137435625 2 1 5.3e-11 1.5e-08 9.7e-03 79 DARS
22 2 168949234 170419444 1 1 3.3e-08 2.8e-09 1.5e-06 34 NOSTRIN
23 2 177559549 179175022 2 1 5.7e-11 1.1e-08 5.7e-01 99 AC073834.3
24 2 218300530 219878756 2 2 2.9e-10 2.3e-11 4.1e-06 52 CXCR2 PNKD
25 2 231967886 233349588 1 1 2.0e-10 4.2e-10 4.4e-01 98 RP11-690I21.1
26 2 241805851 243048760 1 1 4.8e-17 6.3e-15 6.3e-01 100 BOK
27 3 13469611 14880436 1 1 3.8e-07 2.5e-09 1.6e-06 35 TMEM43
28 3 40537829 41986787 1 1 2.6e-08 1.3e-07 8.5e-01 100 CTNNB1
29 3 48618666 50620043 10 2 3.4e-10 9.1e-08 9.1e-01 100 GPX1 RNF123
30 3 52426884 53860103 1 1 3.5e-07 6.4e-06 4.0e-01 96 RFT1
31 3 56629678 58613378 3 1 1.1e-12 1.0e-10 4.0e-02 90 PDE12
32 3 128334272 129714372 1 1 8.7e-08 3.2e-09 8.6e-03 80 H1FX
33 3 140350567 141867638 1 1 1.4e-09 1.1e-09 1.0e+00 100 ZBTB38
34 3 157125828 159106064 3 1 9.3e-12 1.7e-10 3.2e-01 98 RP11-538P18.2
35 4 686563 2058475 1 1 5.9e-08 2.7e-06 1.7e-01 92 CRIPAK
36 4 2825660 4219590 1 1 2.3e-08 9.8e-07 4.8e-03 67 LRPAP1
37 4 17104059 18533844 2 1 3.2e-36 5.7e-31 1.5e-03 92 DCAF16
38 4 57080198 58531645 3 1 9.9e-09 3.1e-09 7.8e-02 91 NOA1
39 4 105373669 107622327 5 6 5.6e-26 1.7e-29 NaN NaN GSTCD INTS12 PPA2
40 4 144230902 146788825 5 1 2.1e-40 6.0e-40 7.0e-09 81 RP11-361D14.2
41 5 42908384 44398696 1 1 1.4e-07 8.8e-07 1.0e-05 19 NNT
42 5 77083651 78753539 1 1 4.0e-08 1.1e-12 6.1e-07 51 LHFPL2
43 5 107390303 109224099 1 1 3.0e-08 5.5e-07 1.9e-02 78 FER
44 5 114443019 115851911 1 1 1.5e-07 1.7e-06 8.0e-01 100 CDO1
45 5 121480516 123449266 2 2 1.1e-12 8.4e-13 5.8e-01 99 CEP120 CTB-36H16.2
46 5 130936652 132401730 2 1 3.4e-08 2.7e-07 3.5e-02 83 SLC22A4
47 5 139323257 141214127 8 1 5.7e-10 6.7e-08 4.5e-01 98 PCDHB5
48 5 147012186 148712150 3 2 8.9e-21 2.3e-26 1.5e-05 83 HTR4 SPINK9
49 5 149903130 151338753 1 1 1.1e-07 2.3e-06 4.3e-01 97 GM2A
50 5 156009720 157697754 2 3 9.5e-15 1.8e-13 7.2e-01 100 ADAM19
51 5 176040488 177260129 2 2 7.2e-09 5.5e-09 3.2e-02 86 MXD3 RAB24
52 6 25266147 26689223 2 3 8.5e-12 3.4e-14 2.9e-01 98 TRIM38 U91328.21
53 6 33745071 36804187 13 3 7.8e-27 1.1e-23 2.8e-25 -7 C6orf106 TEAD3 ZNF76
54 6 80120201 81763771 2 1 1.7e-09 1.2e-09 1.0e+00 100 RP11-250B2.6
55 6 108994161 110843638 7 1 1.2e-13 8.3e-14 5.7e-08 47 SMPD2
56 6 115569351 117481404 4 1 6.4e-09 5.8e-08 2.4e-02 83 FAM26F
57 6 125970401 127355237 1 1 5.2e-16 2.9e-19 1.2e-04 82 CENPW
58 6 129638583 131163098 2 1 4.6e-17 5.5e-23 8.0e-14 43 RP11-73O6.3
59 6 134905567 136516257 1 1 2.2e-07 1.1e-06 2.1e-01 93 AHI1
60 6 151743948 153655470 1 1 3.1e-07 1.8e-08 4.0e-05 47 SYNE1
61 7 6502367 7988091 1 1 9.0e-10 9.9e-09 1.2e-02 81 C1GALT1
62 7 98829666 100221867 1 1 9.7e-08 1.1e-05 9.4e-01 100 GJC3
63 7 149847287 151252618 1 1 1.3e-07 5.3e-08 7.1e-03 76 AOC1
64 8 8092025 9669775 3 1 2.9e-08 1.3e-07 2.5e-02 82 ERI1
65 8 11527910 12966739 1 1 4.1e-08 5.9e-07 4.4e-02 84 FAM66A
66 8 123101743 124679448 1 1 1.4e-08 2.0e-10 2.7e-03 78 ZHX2
67 8 130062993 131498180 1 1 4.1e-13 2.3e-13 1.2e-01 95 GSDMC
68 8 135106207 136500554 1 1 1.1e-09 2.2e-10 3.3e-02 89 AC083843.1
69 9 97945796 100049972 2 2 1.2e-07 4.6e-07 1.4e-01 91 CDC14B ERCC6L2
70 9 100871717 102304304 1 1 3.1e-07 2.5e-05 5.8e-03 57 GALNT12
71 9 135629944 137034272 1 1 4.9e-08 1.0e-11 2.6e-05 62 CACFD1
72 9 138403706 139836362 1 1 3.4e-16 3.7e-14 4.1e-01 99 QSOX2
73 10 11515875 13569805 3 2 1.3e-20 1.8e-24 2.7e-04 87 CDC123 NUDT5
74 10 30435876 32016090 1 1 1.6e-07 6.8e-08 2.5e-02 83 ZNF438
75 10 63870456 65606229 2 1 1.5e-11 2.1e-09 3.1e-02 87 ADO
76 10 74317852 76323150 6 3 1.1e-09 8.8e-10 1.0e+00 100 DNAJC9-AS1 RP11-574K11.5 SEC24C
77 10 76664253 79018276 1 1 2.3e-12 2.3e-16 1.2e-05 71 C10orf11
78 10 80443273 81901722 1 1 1.3e-07 1.2e-06 4.8e-06 12 ZCCHC24
79 10 95379543 96818402 1 1 3.4e-08 1.4e-07 6.0e-01 99 NOC3L
80 11 8348340 9847690 1 1 1.1e-08 9.5e-07 9.9e-01 100 SCUBE2
81 11 46010847 48360648 11 9 1.5e-09 9.2e-10 NaN NaN ACP2 C1QTNF4 MTCH2 PSMC3 Y_RNA ZNF408
82 11 61627881 63110149 7 1 4.7e-11 1.0e-10 1.0e+00 100 ROM1
83 11 65549606 69476279 8 3 1.5e-24 1.0e-22 1.0e+00 100 DPP3 IGHMBP2 RAD9A
84 11 72399607 74006925 3 1 1.5e-10 9.3e-09 1.9e-01 95 FAM168A
85 12 27616589 29042392 1 1 1.7e-10 5.1e-10 2.4e-01 96 RP11-967K21.1
86 12 30084002 31526510 1 1 7.1e-09 2.0e-09 1.0e+00 100 IPO8
87 12 55633142 57684978 13 4 2.1e-10 1.2e-10 1.0e+00 100 AC034102.1 RP11-977G19.11
88 12 93165619 94589220 1 1 4.7e-09 4.3e-16 1.1e-09 44 MRPL42
89 12 95167773 96606889 1 1 3.8e-08 5.6e-06 1.7e-01 91 METAP2
90 13 49557805 51390447 4 6 1.2e-14 1.3e-14 1.0e+00 100 DLEU2 EBPL KPNA3 TRIM13
91 13 110598964 112060514 1 1 2.6e-07 2.1e-07 6.2e-02 87 CARS2
92 13 114302502 115106996 1 1 3.5e-07 1.5e-06 9.3e-02 88 CDC16
93 14 92286262 93847625 1 1 1.7e-12 8.5e-13 1.0e+00 100 RIN3
94 14 104497543 105932544 2 1 2.4e-07 2.5e-07 1.0e+00 100 ADSSL1
95 15 70697945 73087366 2 2 3.5e-09 1.3e-11 6.2e-03 84 MYO9A THSD4
96 15 73524629 74915888 1 1 4.4e-10 5.7e-17 5.8e-09 52 LOXL1-AS1
97 15 78032707 79611011 5 1 2.0e-12 1.9e-13 2.8e-02 91 PSMA4
98 15 82250003 85895721 22 13 1.5e-16 2.2e-29 NaN NaN AC103965.1 CSPG4P11 GOLGA6L4 GOLGA6L5 LOC80154 RP11-152F13.7 RP11-382A20.2 WHAMM ZSCAN2
99 15 98944630 101209341 4 2 7.9e-09 2.2e-11 2.0e-08 30 CTD-3076O17.1 SYNM
100 16 2741812 5510848 7 2 2.8e-12 1.3e-11 5.2e-03 83 CLUAP1 ZNF500
101 16 14173903 15369019 1 1 3.7e-08 3.8e-06 1.2e-02 70 NPIPA2
102 16 29905882 31892919 18 1 6.2e-13 3.4e-11 3.2e-01 98 RP11-196G11.2
103 16 68681792 71093625 12 3 1.6e-13 6.3e-16 3.9e-01 99 NFAT5 NOB1 TMED6
104 16 88030355 89448663 1 1 4.5e-09 2.5e-08 6.0e-03 76 SNAI3-AS1
105 17 923916 2420934 3 1 4.9e-10 3.5e-09 2.8e-01 97 SERPINF1
106 17 29482878 31275580 7 1 1.5e-08 1.9e-08 1.0e+00 100 RP11-640N20.1
107 17 36211659 37597185 1 1 2.1e-09 2.7e-09 1.0e+00 100 PCGF2
108 17 42774693 45876022 23 1 1.9e-30 1.8e-27 9.9e-03 94 LRRC37A2
109 17 45930584 47389935 3 1 4.0e-09 1.2e-06 2.7e-03 62 HOXB4
110 17 60821100 63531331 19 6 3.6e-22 1.2e-19 1.0e+00 100 CD79B CYB561 ICAM2 PLEKHM1P SMARCD2
111 17 79202465 80694826 5 1 7.4e-16 1.5e-14 1.0e-01 96 ASPSCR1
112 18 8010444 9532097 1 1 4.6e-09 2.2e-09 3.2e-02 87 SOGA2
113 18 43698447 45196373 1 1 3.2e-07 1.2e-06 6.2e-01 99 PIAS2
114 19 10068513 11873382 2 2 1.4e-08 3.3e-11 9.4e-04 75 ILF3-AS1 SMARCA4
115 20 9925555 11347455 1 1 5.3e-10 2.9e-10 8.4e-04 72 JAG1
116 20 24423937 26307797 8 1 2.2e-08 3.2e-08 8.0e-02 90 ABHD12
117 20 30060562 31870640 4 1 3.3e-08 1.6e-08 1.0e+00 100 TSPY26P
118 20 32603830 35226873 5 2 7.1e-10 1.4e-08 1.2e-01 92 ERGIC3 TP53INP2
119 20 46838455 48591758 4 1 4.5e-12 1.1e-12 1.3e-02 88 ARFGEF2
120 20 61636050 62912463 4 1 6.0e-11 6.0e-10 2.1e-02 86 TPD52L2
121 22 17581838 19203078 1 1 1.3e-11 2.7e-10 1.8e-01 96 MICAL3
122 22 29585080 31360592 3 2 2.4e-11 2.3e-13 3.9e-02 92 CTA-85E5.10 MTMR3

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Alzheimer’s Disease (including proxy) 1.36 2 0 0.0 0.00 1.0e+00 GJC3 RP11-196G11.2
Crohns Disease (2017) 1.63 9 8 24.2 0.20 6.0e-01 ADCY3 ADO GPX1 RFT1 RP11-574K11.5 SEC24C SLC22A4 TPD52L2 ZBTB38
Irritable Bowel Disease (IBD) 1.54 8 4 12.1 0.01 9.8e-01 ADCY3 ADO CTSS GPX1 PNKD RP11-574K11.5 SLC22A4 TPD52L2
Ulcerative Colitis (UC) 1.25 3 1 3.0 0.00 1.0e+00 GPX1 RNF123 SLC22A4
Major Depression (MDD) 1.26 1 0 0.0 0.00 1.0e+00 GPX1
Reaction Time 1.19 3 1 3.0 0.00 1.0e+00 LRRC37A2 SCUBE2 SMARCA4
Verbal and Numeric Reasoning (VNR) 2.10 15 9 27.3 -0.73 8.3e-04 AC034102.1 ACP2 C1QTNF4 CDC14B CENPW DCAF16 GPX1 MTCH2 PPA2 PSMC3 RNF123 RP11-152F13.7 U91328.21 UBXN2A Y_RNA
Breast Cancer 1.49 9 6 18.2 -0.13 7.4e-01 ADCY3 ADSSL1 GPX1 LRRC37A2 RIN3 RP11-73O6.3 SLC22A4 SYNE1 ZBTB38
Ovarian Cancer 1.22 3 0 0.0 0.00 1.0e+00 DNALI1 HOXB4 LRRC37A2
Prostate Cancer 1.60 2 1 3.0 0.00 1.0e+00 GPX1 MDM4
Age at First Birth 1.26 2 1 3.0 0.00 1.0e+00 ABHD12 GPX1
Body Mass Index (BMI) (2010) 1.96 6 4 12.1 0.99 3.5e-05 ACP2 ADCY3 C1QTNF4 MTCH2 PSMC3 Y_RNA
Crohns Disease (2012) 1.55 5 2 6.1 -0.63 2.6e-01 ADO GPX1 RFT1 SLC22A4 TPD52L2
HDL Cholesterol 2.68 7 6 18.2 -0.81 4.1e-03 ACP2 C1QTNF4 C6orf106 MTCH2 PSMC3 Y_RNA ZNF408
LDL Cholesterol 1.26 2 2 6.1 0.00 1.0e+00 CACFD1 SMARCA4
Lupus 1.28 1 0 0.0 0.00 1.0e+00 ZNF76
Neuroticism 1.56 3 0 0.0 0.00 1.0e+00 FAM66A LRRC37A2 MTCH2
Schizophrenia 1.31 3 1 3.0 0.71 2.9e-01 AC103965.1 FAM66A GOLGA6L5
Triglycerides 1.31 1 0 0.0 0.00 1.0e+00 RP11-196G11.2
Ulcerative Colitis 1.34 1 1 3.0 0.00 1.0e+00 GPX1
Blood Eosinophil Count 1.58 31 19 57.6 0.55 1.1e-03 AC034102.1 AC103965.1 ACP2 ADO AHI1 CACFD1 CTSS DLEU2 EBPL FAM136A FAM26F HTR4 KIAA1614 KPNA3 LRRC37A2 NOA1 NOB1 NOSTRIN PCGF2 PSMC3 RFT1 RIN3 RP11-73O6.3 SLC22A4 SMARCA4 SMPD2 TEAD3 TRIM63 TSPY26P ZNF76 ZSCAN2
Blood Platelet Count 1.45 38 28 84.8 0.34 2.7e-02 ABHD12 AC103965.1 ACP2 ADO C1QTNF4 C6orf106 CACFD1 CDC14B CEP120 CTSS DCAF16 DENND2D FAM136A FER GIPC2 GOLGA6L4 HTR4 KIAA1614 MTCH2 MTMR3 NOA1 PDE12 PNKD PPA2 PSMC3 RIN3 RP11-361D14.2 SCMH1 SLC22A4 SMARCD2 SMPD2 TPD52L2 TRIM63 Y_RNA ZCCHC24 ZHX2 ZNF500 ZSCAN2
Blood Red Count 1.23 24 15 45.5 0.04 8.6e-01 AC103965.1 AHI1 AOC1 ASPSCR1 C6orf106 CACFD1 CD79B CENPW DARS FAM136A HOXB4 LRRC37A2 MST1P2 MYO9A NFAT5 NOB1 RAD9A RP11-196G11.2 RP11-73O6.3 RP11-977G19.11 SMPD2 SNAI3-AS1 ZBTB38 ZNF500
Blood White Count 2.00 39 31 93.9 0.72 2.7e-08 ACP2 ADO AHI1 C1QTNF4 CACFD1 CDC14B CENPW CEP120 CTB-36H16.2 DCAF16 EBPL FBLN7 FER GM2A GPX1 HOXB4 HTR4 KIAA1614 MICAL3 MTCH2 NOA1 NOB1 NOSTRIN PCDHB5 PNKD PSMC3 RFT1 RIN3 RP11-73O6.3 SCMH1 SLC22A4 SMARCD2 SMPD2 SPINK9 UBXN2A Y_RNA ZHX2 ZNF500 ZNF76
Heel T-Score 2.49 53 40 121.2 0.15 2.6e-01 AC034102.1 AC103965.1 ACP2 ADCY3 ASPSCR1 CACFD1 CDKN2C CEP120 CRIPAK CSPG4P11 CTA-85E5.10 CTB-36H16.2 CTNNB1 CTSS CXCR2 DCAF16 DIRAS3 DLEU2 EBPL GOLGA6L5 GSDMC IGHMBP2 IPO8 JAG1 JMJD4 KIAA1614 KPNA3 LRRC37A2 MTMR3 NOA1 PDE12 PLEKHM1P PSMC3 RAB24 RFT1 ROM1 RP11-196G11.2 RP11-361D14.2 RP11-73O6.3 RP11-967K21.1 SCMH1 SEC24C SF3A3 SMARCD2 SNAI3-AS1 SYNE1 THSD4 TRIM13 WHAMM ZBTB38 ZCCHC24 ZNF408 ZNF76
BMI 2.28 31 22 66.7 0.64 3.8e-05 AC034102.1 ACP2 ADCY3 ARFGEF2 C1QTNF4 C6orf106 CDC14B CEP120 CTNNB1 DCAF16 GPX1 HOXB4 HTR4 IGHMBP2 LOXL1-AS1 MST1P2 MTCH2 NFAT5 NOB1 PSMC3 RAB24 RFT1 RNF123 RP11-196G11.2 RP11-538P18.2 RP11-73O6.3 SMARCD2 TMED6 TSPY26P Y_RNA ZNF408
Height 9.31 126 115 348.5 -0.88 4.9e-45 AC083843.1 AC103965.1 ACP2 ADCY3 ADO AHI1 AOC1 ARFGEF2 ASPSCR1 BOK C10orf11 C1QTNF4 C6orf106 CACFD1 CD79B CDC123 CDC14B CDC16 CDKN2C CDO1 CENPW CEP120 CLUAP1 CRIPAK CSPG4P11 CTA-85E5.10 CTD-3076O17.1 CTNNB1 CTSS CXCR2 CYB561 DCAF16 DHDDS DIRAS3 DLEU2 DNAJC9-AS1 DNALI1 DPP3 EBPL EFEMP1 ERCC6L2 ERGIC3 FAM136A FAM26F FER GIPC2 GJC3 GOLGA6L4 GOLGA6L5 GPX1 GSDMC H1FX HOXB4 ICAM2 IGHMBP2 ILF3-AS1 INTS12 IPO8 JAG1 JMJD4 KIAA1614 KPNA3 LHFPL2 LOXL1-AS1 LRPAP1 LRRC37A2 MDM4 MICAL3 MRPL42 MST1P2 MTCH2 MTMR3 MXD3 MYO9A NFAT5 NOA1 NOB1 NOC3L NOSTRIN NPIPA2 PCDHB5 PIAS2 PLEKHM1P PNKD PPA2 PSMC3 QSOX2 RAB24 RAD9A RFT1 RP11-250B2.6 RP11-361D14.2 RP11-382A20.2 RP11-538P18.2 RP11-640N20.1 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 SCMH1 SERPINF1 SF3A3 SLC22A4 SMARCA4 SMARCD2 SMPD2 SNAI3-AS1 SYNE1 TEAD3 TMED6 TMEM43 TP53INP2 TPD52L2 TRIM13 TRIM63 TSEN15 UBXN2A Y_RNA ZBTB38 ZCCHC24 ZHX2 ZNF408 ZNF500 ZNF76 ZSCAN2
Waist Hip Ratio (WHR) 1.78 24 14 42.4 0.25 2.2e-01 AC103965.1 ADCY3 ASPSCR1 C6orf106 CD79B CENPW CLUAP1 DLEU2 EBPL ERGIC3 GOLGA6L5 GPX1 H1FX IPO8 LRRC37A2 NFAT5 RAB24 RAD9A ROM1 RP11-361D14.2 RP11-73O6.3 SCUBE2 SMARCA4 ZBTB38
Systolic Blood Pressure 1.68 30 19 57.6 0.38 3.3e-02 ACP2 ADCY3 ADO ARFGEF2 CARS2 CDC123 CDC16 DCAF16 EFEMP1 FER GIPC2 GPX1 HOXB4 HTR4 JMJD4 LRRC37A2 MICAL3 MTCH2 NNT NUDT5 PCDHB5 PNKD RIN3 RP11-538P18.2 SF3A3 SPINK9 Y_RNA ZHX2 ZNF408 ZNF500
Smoking Status 1.38 5 2 6.1 0.21 7.4e-01 AC034102.1 GPX1 LRRC37A2 NOB1 RFT1
Allergy or Eczema 1.49 6 4 12.1 0.59 2.2e-01 AC034102.1 AHI1 C6orf106 RP11-574K11.5 SLC22A4 ZBTB38
Cardiovascular Disease 1.63 15 7 21.2 0.97 5.9e-10 ACP2 C1GALT1 CDC16 DCAF16 FAM136A HTR4 MXD3 RP11-196G11.2 RP11-538P18.2 SLC22A4 SMARCA4 SMARCD2 TSPY26P ZNF408 ZNF76
Hypothyroidism (self reported) 1.31 5 2 6.1 0.98 4.4e-03 AC034102.1 AHI1 C1QTNF4 MTCH2 RIN3
Respiratory disease 2.22 10 6 18.2 0.92 7.6e-05 AC034102.1 ADAM19 AHI1 HTR4 NOA1 RIN3 RP11-574K11.5 SLC22A4 TPD52L2 ZNF76
Type 2 Diabetes (T2D) 1.84 8 2 6.1 0.73 3.9e-02 C1GALT1 CENPW HOXB4 HTR4 NOB1 NUDT5 TPD52L2 Y_RNA
Lung FEV1/FVC ratio 8.25 64 50 151.5 -0.74 1.8e-13 AC034102.1 AC103965.1 ADAM19 ADCY3 ADO C10orf11 C1GALT1 C6orf106 CDC123 CDKN2C CENPW CTA-85E5.10 CTNNB1 DENND2D DNAJC9-AS1 DNALI1 EFEMP1 ERGIC3 FAM168A GIPC2 GJC3 GM2A GOLGA6L4 GOLGA6L5 GPX1 GSTCD HTR4 INTS12 KPNA3 LONRF2 METAP2 MICAL3 MST1P2 MTMR3 MYO9A NNT NOA1 NUDT5 PCGF2 PDE12 PLEKHM1P PPA2 PSMA4 RNF123 ROM1 RP11-152F13.7 RP11-361D14.2 RP11-382A20.2 RP11-574K11.5 RP11-640N20.1 SCUBE2 SEC24C SLC22A4 SMPD2 SOGA2 SPINK9 SYNM THSD4 TMEM43 TSPY26P WHAMM ZBTB38 ZNF76 ZSCAN2
Lung FVC 5.89 90 69 209.1 -0.87 1.8e-30 ABHD12 AC034102.1 AC073834.3 ADSSL1 AHI1 ANGPTL1 AOC1 ARFGEF2 ASPSCR1 BOK C10orf11 C1GALT1 CACFD1 CD79B CDC123 CENPW CEP120 CLUAP1 CTA-85E5.10 CTB-36H16.2 CTSS CXCR2 DARS DCAF16 DHDDS DIRAS3 DPP3 EBPL EFEMP1 ERGIC3 FAM136A FAM26F GALNT12 GM2A GPX1 GSTCD HOXB4 HTR4 IGHMBP2 INTS12 IPO8 JAG1 KIAA1614 LONRF2 LRPAP1 LRRC37A2 MDM4 MICAL3 MST1P2 NFAT5 NNT NOA1 NOB1 NPIPA2 NUDT5 PCDHB5 PDE12 PLEKHM1P PPA2 PSMA4 QSOX2 RAD9A RIN3 RNF123 ROM1 RP11-152F13.7 RP11-196G11.2 RP11-250B2.6 RP11-361D14.2 RP11-382A20.2 RP11-538P18.2 RP11-574K11.5 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 SCMH1 SEC24C SLC22A4 SMPD2 SNAI3-AS1 SOGA2 TEAD3 THSD4 TPD52L2 TRIM63 TSPY26P UBXN2A WHAMM ZBTB38 ZNF76
Neuroticism 1.53 9 4 12.1 0.16 6.8e-01 AHI1 C1QTNF4 CENPW GPX1 LRRC37A2 MTCH2 RP11-196G11.2 SNAI3-AS1 Y_RNA
Chronotype (morning person) 1.40 4 0 0.0 1.00 1.3e-03 C1QTNF4 CRIPAK CTSS CYB561
Hair Pigment 0.43 16 13 39.4 -0.16 5.1e-01 ACP2 ADO ASPSCR1 C1QTNF4 DPP3 ERGIC3 FAM136A IGHMBP2 NOA1 RP11-73O6.3 SMARCA4 SNAI3-AS1 TP53INP2 ZBTB38 ZNF408 ZNF76
Tanning 0.40 9 8 24.2 -0.37 2.9e-01 ADCY3 ADO CTSS ERGIC3 METAP2 MXD3 RP11-152F13.7 SNAI3-AS1 TP53INP2
Hand grip strength (left) 3.80 32 21 63.6 0.96 2.8e-19 ACP2 ADCY3 AOC1 ARFGEF2 C1QTNF4 C6orf106 CD79B CRIPAK CYB561 DARS DCAF16 ERGIC3 FER HOXB4 IGHMBP2 JAG1 JMJD4 LOXL1-AS1 LRRC37A2 MTCH2 NOB1 PSMC3 RAD9A RFT1 RP11-250B2.6 RP11-73O6.3 SLC22A4 Y_RNA ZBTB38 ZCCHC24 ZNF500 ZNF76
Number of treatments/medications taken 1.44 2 1 3.0 0.00 1.0e+00 DCAF16 GPX1
Sensitivity / hurt feelings 1.34 1 1 3.0 0.00 1.0e+00 LRRC37A2
Frequency of depressed mood in last 2 weeks 1.32 1 0 0.0 0.00 1.0e+00 MTCH2
Hearing difficulty/problems: Yes 0.96 1 0 0.0 0.00 1.0e+00 FER
Relative age of first facial hair 1.45 4 3 9.1 -0.96 4.3e-02 C6orf106 LRRC37A2 NPIPA2 ZBTB38
Systolic blood pressure, automated reading 1.94 21 5 15.2 -0.69 3.3e-04 ADCY3 ADO CDC16 DCAF16 EFEMP1 ERI1 FAM66A FER GPX1 HOXB4 HTR4 LRRC37A2 NUDT5 PPA2 RP11-538P18.2 SF3A3 SPINK9 U91328.21 ZHX2 ZNF408 ZNF500
Medication: Co-codamol 1.11 1 0 0.0 0.00 1.0e+00 GPX1
Medication: Metformin 1.71 2 0 0.0 0.00 1.0e+00 NUDT5 Y_RNA
Diabetes (mother) 1.49 1 1 3.0 0.00 1.0e+00 NUDT5
Pack years adult smoking proportion 2.57 3 1 3.0 0.00 1.0e+00 CYB561 GPX1 PSMA4
Impedance of leg (right) 2.55 30 20 60.6 0.20 2.6e-01 AC034102.1 AC103965.1 ADCY3 AOC1 CD79B CDO1 CEP120 CSPG4P11 CTD-3076O17.1 CTSS ERGIC3 ERI1 FAM66A GOLGA6L4 GOLGA6L5 GPX1 IGHMBP2 LOXL1-AS1 MST1P2 NNT PPA2 RAB24 RAD9A RFT1 RIN3 RP11-382A20.2 RP11-73O6.3 SMPD2 SNAI3-AS1 ZSCAN2
Leg fat-free mass (left) 4.35 61 44 133.3 0.88 2.6e-22 AC034102.1 AC083843.1 AOC1 BOK C6orf106 CD79B CDC14B CDC16 CDKN2C CENPW CEP120 CRIPAK CTNNB1 DCAF16 DLEU2 EBPL EFEMP1 ERGIC3 ERI1 GIPC2 GPX1 GSDMC H1FX IGHMBP2 ILF3-AS1 IPO8 JMJD4 KIAA1614 LHFPL2 MRPL42 MXD3 NOSTRIN NPIPA2 PNKD PPA2 QSOX2 RAD9A RIN3 RP11-196G11.2 RP11-250B2.6 RP11-361D14.2 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 SCMH1 SERPINF1 SF3A3 SLC22A4 SMARCA4 SMARCD2 SMPD2 SYNE1 TP53INP2 TRIM13 TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZNF500 ZNF76
Trunk fat percentage 3.04 33 26 78.8 -0.14 4.1e-01 ABHD12 AC103965.1 ACP2 ADCY3 ARFGEF2 C1QTNF4 C6orf106 CENPW CSPG4P11 CTD-3076O17.1 CTNNB1 DARS EFEMP1 GOLGA6L4 GOLGA6L5 GPX1 HTR4 LRRC37A2 MTCH2 NOB1 PSMC3 RAD9A RIN3 ROM1 RP11-196G11.2 RP11-78I14.1 SYNM TEAD3 TP53INP2 TPD52L2 Y_RNA ZBTB38 ZSCAN2
Hand grip strength (right) 3.75 35 23 69.7 0.96 7.7e-20 ADCY3 ANGPTL1 AOC1 ARFGEF2 C1QTNF4 C6orf106 CD79B CDC14B CRIPAK CYB561 DARS DCAF16 ERGIC3 HOXB4 JAG1 JMJD4 LOXL1-AS1 LRRC37A2 MTCH2 NOB1 NOSTRIN PCGF2 PSMC3 RAD9A RFT1 RP11-250B2.6 RP11-73O6.3 SCMH1 SLC22A4 SMARCD2 TP53INP2 Y_RNA ZBTB38 ZCCHC24 ZNF76
Current tobacco smoking 1.49 4 0 0.0 0.27 7.3e-01 FAM66A MTCH2 TPD52L2 Y_RNA
Fed-up feelings 1.45 3 1 3.0 0.00 1.0e+00 GPX1 LRRC37A2 ZNF408
Relative age voice broke 1.32 2 1 3.0 0.00 1.0e+00 LRRC37A2 SCMH1
Taking other prescription medications 1.34 2 1 3.0 0.00 1.0e+00 AHI1 GPX1
Age when periods started (menarche) 2.04 11 7 21.2 0.41 2.2e-01 ADCY3 C1QTNF4 CENPW GPX1 HTR4 MTCH2 NFAT5 NOB1 NPIPA2 PIAS2 Y_RNA
Heel bone mineral density (BMD) T-score, automated (left) 2.09 13 8 24.2 -0.31 2.4e-01 ACP2 CRIPAK DLEU2 EBPL ERI1 FAM66A IGHMBP2 JAG1 NOA1 SF3A3 SYNE1 TRIM13 ZNF408
High blood pressure 1.89 16 6 18.2 -0.94 4.0e-09 ACP2 ARFGEF2 C1GALT1 CDC16 DCAF16 ERI1 FAM66A HTR4 PSMC3 RP11-196G11.2 RP11-538P18.2 SLC22A4 TSPY26P U91328.21 ZNF408 ZNF500
Hayfever, allergic rhinitis or eczema 1.37 5 4 12.1 -0.59 3.0e-01 AC034102.1 AHI1 C6orf106 SLC22A4 ZBTB38
Medication: Levothyroxine sodium 1.24 3 1 3.0 0.00 1.0e+00 AC034102.1 AHI1 ERI1
Sitting height 7.65 98 89 269.7 0.90 6.9e-42 ABHD12 AC073834.3 AC083843.1 AC103965.1 ACP2 ADCY3 AOC1 ARFGEF2 ASPSCR1 BOK C1QTNF4 C6orf106 CACFD1 CD79B CDC14B CDC16 CDKN2C CDO1 CENPW CEP120 CRIPAK CSPG4P11 CTB-36H16.2 CTD-3076O17.1 CTNNB1 CXCR2 CYB561 DCAF16 DHDDS DLEU2 EBPL EFEMP1 ERCC6L2 ERGIC3 FAM136A FAM26F GIPC2 GJC3 GOLGA6L4 GOLGA6L5 GSDMC H1FX HOXB4 ICAM2 IGHMBP2 ILF3-AS1 JAG1 JMJD4 KIAA1614 LHFPL2 LOXL1-AS1 LRRC37A2 MRPL42 MST1P2 MTCH2 MXD3 NFAT5 NOB1 NOC3L NOSTRIN PCDHB5 PNKD PPA2 PSMC3 QSOX2 RAD9A RFT1 RP11-250B2.6 RP11-361D14.2 RP11-538P18.2 RP11-640N20.1 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 SCMH1 SERPINF1 SF3A3 SLC22A4 SMARCD2 SMPD2 SNAI3-AS1 SYNE1 TEAD3 TMED6 TP53INP2 TRIM13 TRIM63 TSEN15 UBXN2A Y_RNA ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76 ZSCAN2
Chronic bronchitis/emphysema (father) 1.71 1 1 3.0 0.00 1.0e+00 PSMA4
Body mass index (BMI) 2.38 26 16 48.5 -0.72 1.0e-05 AC034102.1 ACP2 ADCY3 ARFGEF2 C1QTNF4 C6orf106 CEP120 DARS DCAF16 ERI1 FAM66A GPX1 HTR4 IGHMBP2 LOXL1-AS1 MST1P2 MTCH2 NFAT5 NOB1 PSMC3 RFT1 RP11-196G11.2 TMED6 TRIM38 Y_RNA ZNF408
Impedance of leg (left) 2.50 28 21 63.6 0.17 3.6e-01 AC034102.1 AC103965.1 ADCY3 AOC1 CD79B CDO1 CEP120 CSPG4P11 CTD-3076O17.1 CTSS ERGIC3 ERI1 FAM66A GOLGA6L4 GOLGA6L5 GPX1 IGHMBP2 LOXL1-AS1 MST1P2 NNT PPA2 RAB24 RAD9A RIN3 RP11-382A20.2 RP11-73O6.3 SMPD2 ZSCAN2
Leg predicted mass (left) 4.35 61 45 136.4 0.88 2.6e-22 AC034102.1 AC083843.1 AOC1 BOK C6orf106 CD79B CDC14B CDC16 CDKN2C CENPW CEP120 CRIPAK CTNNB1 DCAF16 DLEU2 EBPL EFEMP1 ERGIC3 ERI1 GIPC2 GPX1 GSDMC H1FX IGHMBP2 ILF3-AS1 IPO8 JMJD4 KIAA1614 LHFPL2 MRPL42 MXD3 NOSTRIN NPIPA2 PNKD PPA2 QSOX2 RAD9A RIN3 RP11-196G11.2 RP11-250B2.6 RP11-361D14.2 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 SCMH1 SERPINF1 SF3A3 SLC22A4 SMARCA4 SMARCD2 SMPD2 SYNE1 TP53INP2 TRIM13 TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZNF500 ZNF76
Trunk fat mass 2.95 38 28 84.8 0.28 7.3e-02 ABHD12 AC103965.1 ACP2 ADCY3 BOK C1QTNF4 C6orf106 CDC16 CEP120 CSPG4P11 CTD-3076O17.1 CTNNB1 EFEMP1 ERGIC3 GOLGA6L4 GOLGA6L5 GPX1 H1FX HTR4 LRRC37A2 MTCH2 NOB1 PSMC3 RAD9A ROM1 RP11-196G11.2 RP11-361D14.2 RP11-73O6.3 RP11-78I14.1 SMPD2 TP53INP2 TPD52L2 TRIM13 TRIM38 Y_RNA ZBTB38 ZNF500 ZSCAN2
Waist circumference 1.98 22 15 45.5 -0.16 4.5e-01 ABHD12 AC034102.1 ACP2 ADCY3 C1QTNF4 C6orf106 CEP120 CTNNB1 GOLGA6L4 GPX1 HTR4 MTCH2 NFAT5 NOB1 PSMC3 RAD9A RP11-196G11.2 RP11-78I14.1 TPD52L2 Y_RNA ZBTB38 ZSCAN2
Number of incorrect matches in round 1.38 1 0 0.0 0.00 1.0e+00 RP11-196G11.2
Past tobacco smoking 1.29 3 0 0.0 0.00 1.0e+00 NOA1 NOB1 RP11-977G19.11
Nervous feelings 1.62 5 2 6.1 -0.11 8.6e-01 CENPW ERI1 FAM66A LRRC37A2 RP11-196G11.2
Frequency of tenseness / restlessness in last 2 weeks 1.29 2 2 6.1 0.00 1.0e+00 GPX1 LRRC37A2
Hair/balding pattern: Pattern 2 1.53 2 1 3.0 0.00 1.0e+00 C10orf11 LRRC37A2
Had menopause 1.01 1 0 0.0 0.00 1.0e+00 RP11-73O6.3
Had other major operations 1.55 1 0 0.0 0.00 1.0e+00 PPA2
Forced vital capacity (FVC) 10.62 143 116 351.5 0.98 7.9e-107 ABHD12 AC073834.3 AC083843.1 AC103965.1 ACP2 ADCY3 ADO AHI1 ANGPTL1 AOC1 ARFGEF2 ASPSCR1 BOK C10orf11 C1QTNF4 C6orf106 CACFD1 CD79B CDC123 CDC14B CDC16 CDKN2C CDO1 CENPW CEP120 CLUAP1 CRIPAK CSPG4P11 CTA-85E5.10 CTB-36H16.2 CTD-3076O17.1 CTNNB1 CTSS CXCR2 CYB561 DARS DCAF16 DHDDS DIRAS3 DLEU2 DNAJC9-AS1 DNALI1 DPP3 EBPL EFEMP1 ERCC6L2 ERGIC3 FAM136A FAM26F FER GALNT12 GIPC2 GOLGA6L5 GPX1 GSDMC GSTCD H1FX HOXB4 HTR4 ICAM2 IGHMBP2 ILF3-AS1 INTS12 IPO8 JAG1 JMJD4 KIAA1614 LHFPL2 LONRF2 LOXL1-AS1 LRPAP1 LRRC37A2 MDM4 MICAL3 MRPL42 MST1P2 MTCH2 MXD3 MYO9A NFAT5 NOA1 NOB1 NOSTRIN NPIPA2 NUDT5 PCDHB5 PDE12 PIAS2 PLEKHM1P PNKD PPA2 PSMA4 PSMC3 QSOX2 RAB24 RAD9A RFT1 RIN3 RNF123 ROM1 RP11-152F13.7 RP11-196G11.2 RP11-250B2.6 RP11-361D14.2 RP11-382A20.2 RP11-538P18.2 RP11-574K11.5 RP11-640N20.1 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 SCMH1 SEC24C SERPINF1 SF3A3 SMARCA4 SMARCD2 SMPD2 SNAI3-AS1 SYNE1 TEAD3 TMED6 TMEM43 TP53INP2 TPD52L2 TRIM13 TRIM38 TRIM63 TSEN15 TSPY26P U91328.21 UBXN2A WHAMM Y_RNA ZBTB38 ZCCHC24 ZHX2 ZNF408 ZNF438 ZNF500 ZNF76
Heel bone mineral density (BMD) T-score, automated (right) 2.09 13 5 15.2 -0.32 2.5e-01 ACP2 CRIPAK DLEU2 EBPL ERI1 FAM66A IGHMBP2 NOA1 SF3A3 SYNE1 TRIM13 ZBTB38 ZNF408
Qualifications: None of the above 1.65 5 2 6.1 -0.48 4.2e-01 AC034102.1 GPX1 PPA2 RFT1 RNF123
Mouth/teeth dental problems 0.94 1 0 0.0 0.00 1.0e+00 LRRC37A2
Allergy 1.62 7 4 12.1 0.74 5.6e-02 AC034102.1 AHI1 C6orf106 RP11-574K11.5 SLC22A4 TPD52L2 ZBTB38
Pain all over the body in last month 1.39 1 0 0.0 0.00 1.0e+00 GPX1
Diabetes (self-reported) 1.70 2 0 0.0 0.00 1.0e+00 C1GALT1 CLUAP1
Hayfever/allergic rhinitis (self-reported) 1.21 1 0 0.0 0.00 1.0e+00 AC034102.1
Medication: Simvastatin 1.47 1 0 0.0 0.00 1.0e+00 SMARCA4
Fluid intelligence score 2.07 10 4 12.1 0.84 1.3e-03 ACP2 C1QTNF4 DCAF16 GPX1 MTCH2 PPA2 PSMC3 RNF123 U91328.21 Y_RNA
Neuroticism score 1.67 8 6 18.2 0.22 6.0e-01 C1QTNF4 ERI1 FAM66A GPX1 LRRC37A2 MTCH2 RP11-196G11.2 Y_RNA
Weight 3.46 57 34 103.0 0.73 2.2e-11 ABHD12 AC034102.1 AC103965.1 BOK C1QTNF4 C6orf106 CD79B CDC16 CDKN2C CENPW CEP120 CRIPAK CTD-3076O17.1 CTNNB1 DCAF16 DLEU2 EBPL EFEMP1 ERGIC3 ERI1 GIPC2 GOLGA6L4 GOLGA6L5 GPX1 GSDMC H1FX HTR4 IGHMBP2 ILF3-AS1 LHFPL2 MRPL42 MXD3 NPIPA2 PPA2 RAB24 RAD9A RP11-196G11.2 RP11-361D14.2 RP11-73O6.3 RP11-78I14.1 SCMH1 SERPINF1 SF3A3 SLC22A4 SMARCA4 SMARCD2 SMPD2 SYNE1 TP53INP2 TPD52L2 TRIM13 TRIM38 TSEN15 ZBTB38 ZCCHC24 ZNF500 ZSCAN2
Impedance of arm (right) 2.37 29 23 69.7 0.18 3.2e-01 AC034102.1 AC083843.1 AC103965.1 AOC1 CD79B CENPW CEP120 CSPG4P11 CTD-3076O17.1 EFEMP1 ERI1 FAM66A FBLN7 FER GIPC2 GOLGA6L4 GOLGA6L5 GPX1 IGHMBP2 LOXL1-AS1 LRRC37A2 MRPL42 MST1P2 NNT RFT1 RIN3 ROM1 RP11-73O6.3 SCMH1
Arm fat percentage (right) 2.92 26 15 45.5 -0.79 4.4e-07 ABHD12 ACP2 ADCY3 ARFGEF2 C1QTNF4 C6orf106 CD79B CDC14B CENPW DCAF16 DPP3 ERI1 GPX1 HTR4 MTCH2 NFAT5 NOB1 PSMC3 ROM1 RP11-196G11.2 RP11-78I14.1 TEAD3 TPD52L2 Y_RNA ZNF408 ZNF76
Trunk fat-free mass 6.25 80 66 200.0 0.92 1.2e-38 AC034102.1 AC083843.1 ACP2 ADCY3 AOC1 ARFGEF2 BOK C1QTNF4 C6orf106 CD79B CDC14B CDC16 CDKN2C CENPW CEP120 CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 ERGIC3 FAM136A GIPC2 GJC3 GPX1 GSDMC H1FX ICAM2 IGHMBP2 ILF3-AS1 IPO8 JMJD4 KIAA1614 LHFPL2 MRPL42 MST1P2 MTCH2 MXD3 NOA1 NOSTRIN NPIPA2 PLEKHM1P PNKD PPA2 PSMC3 QSOX2 RAB24 RAD9A RFT1 RIN3 RP11-250B2.6 RP11-361D14.2 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 SCMH1 SERPINF1 SF3A3 SLC22A4 SMARCA4 SMARCD2 SMPD2 SNAI3-AS1 SYNE1 TEAD3 TMEM43 TP53INP2 TRIM13 TRIM63 TSEN15 UBXN2A Y_RNA ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76
Hip circumference 2.89 39 27 81.8 0.35 2.3e-02 AC034102.1 AC103965.1 ACP2 ADCY3 BOK C1QTNF4 C6orf106 CD79B CDC16 CDKN2C CEP120 CTNNB1 DLEU2 EBPL EFEMP1 ERGIC3 ERI1 GIPC2 GOLGA6L4 GPX1 H1FX HTR4 MTCH2 NOB1 PSMC3 RAD9A RP11-196G11.2 RP11-361D14.2 RP11-73O6.3 RP11-78I14.1 SMARCA4 SMPD2 TP53INP2 TPD52L2 TRIM38 Y_RNA ZBTB38 ZNF500 ZSCAN2
Alcohol intake versus 10 years previously 1.09 1 0 0.0 0.00 1.0e+00 GPX1
Father's age at death 1.45 3 1 3.0 0.00 1.0e+00 ERI1 GPX1 PSMA4
Worrier / anxious feelings 1.52 4 3 9.1 0.30 7.0e-01 ERI1 FAM66A LRRC37A2 RP11-196G11.2
Frequency of tiredness / lethargy in last 2 weeks 1.34 2 0 0.0 0.00 1.0e+00 GPX1 MTCH2
Hair/balding pattern: Pattern 3 1.62 2 2 6.1 0.00 1.0e+00 CENPW LRRC37A2
Forced expiratory volume in 1-second (FEV1) 12.00 169 142 430.3 1.00 3.7e-201 ABHD12 AC034102.1 AC073834.3 AC083843.1 AC103965.1 ACP2 ADAM19 ADCY3 ADO ADSSL1 AHI1 ANGPTL1 AOC1 ARFGEF2 ASPSCR1 BOK C10orf11 C1GALT1 C1QTNF4 C6orf106 CACFD1 CARS2 CD79B CDC123 CDC14B CDC16 CDKN2C CDO1 CENPW CEP120 CLUAP1 CRIPAK CSPG4P11 CTA-85E5.10 CTB-36H16.2 CTD-3076O17.1 CTNNB1 CTSS CXCR2 CYB561 DARS DCAF16 DENND2D DHDDS DIRAS3 DLEU2 DNAJC9-AS1 DNALI1 DPP3 EBPL EFEMP1 ERCC6L2 ERGIC3 ERI1 FAM136A FAM168A FAM26F FAM66A FER GALNT12 GIPC2 GJC3 GM2A GOLGA6L4 GOLGA6L5 GPX1 GSDMC GSTCD H1FX HOXB4 HTR4 ICAM2 IGHMBP2 ILF3-AS1 INTS12 IPO8 JAG1 JMJD4 KIAA1614 KPNA3 LHFPL2 LOC80154 LONRF2 LOXL1-AS1 LRPAP1 LRRC37A2 MDM4 METAP2 MICAL3 MRPL42 MST1P2 MTCH2 MTMR3 MXD3 MYO9A NFAT5 NNT NOA1 NOB1 NOC3L NOSTRIN NPIPA2 NUDT5 PCDHB5 PCGF2 PDE12 PIAS2 PLEKHM1P PNKD PPA2 PSMA4 PSMC3 QSOX2 RAB24 RAD9A RFT1 RIN3 RNF123 ROM1 RP11-152F13.7 RP11-196G11.2 RP11-250B2.6 RP11-361D14.2 RP11-382A20.2 RP11-538P18.2 RP11-574K11.5 RP11-640N20.1 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 SCMH1 SCUBE2 SEC24C SERPINF1 SF3A3 SLC22A4 SMARCA4 SMARCD2 SMPD2 SNAI3-AS1 SOGA2 SPINK9 SYNE1 SYNM TEAD3 THSD4 TMED6 TMEM43 TP53INP2 TPD52L2 TRIM13 TRIM38 TRIM63 TSEN15 TSPY26P U91328.21 UBXN2A WHAMM Y_RNA ZBTB38 ZCCHC24 ZHX2 ZNF408 ZNF438 ZNF500 ZNF76 ZSCAN2
Pulse rate 1.21 4 1 3.0 -0.05 9.5e-01 CEP120 CTNNB1 ROM1 ZBTB38
Qualifications: A levels/AS levels or equivalent 1.51 4 2 6.1 0.67 3.3e-01 AC034102.1 GPX1 PIAS2 RNF123
Mouth/teeth dental problems: Dentures 1.27 4 0 0.0 -1.00 1.7e-03 ERI1 GPX1 PSMA4 TRIM38
Asthma 2.53 10 7 21.2 -0.93 3.3e-05 AC034102.1 ADAM19 AHI1 HTR4 RP11-574K11.5 SLC22A4 TPD52L2 TRIM38 U91328.21 ZNF76
Medication: Ibuprofen (e.g. Nurofen) 1.04 1 0 0.0 0.00 1.0e+00 U91328.21
Medication: Cholesterol lowering 1.35 2 0 0.0 0.00 1.0e+00 RP11-196G11.2 SMARCA4
Lung cancer (father) 1.73 1 1 3.0 0.00 1.0e+00 PSMA4
Impedance of arm (left) 2.36 29 22 66.7 0.24 1.8e-01 AC034102.1 AC103965.1 AOC1 CD79B CENPW CEP120 CSPG4P11 CTD-3076O17.1 EFEMP1 ERI1 FAM66A FER GIPC2 GOLGA6L4 GOLGA6L5 GPX1 IGHMBP2 LOXL1-AS1 LRRC37A2 MRPL42 MST1P2 NNT RFT1 RIN3 ROM1 RP11-73O6.3 SCMH1 TSPY26P ZSCAN2
Arm fat mass (right) 2.32 25 16 48.5 -0.31 1.1e-01 ABHD12 AC034102.1 ACP2 ADCY3 C1QTNF4 C6orf106 CEP120 CTNNB1 ERGIC3 ERI1 FAM66A GPX1 HTR4 IGHMBP2 MTCH2 NOB1 PSMC3 RP11-196G11.2 RP11-73O6.3 RP11-78I14.1 TP53INP2 TPD52L2 TRIM38 Y_RNA ZBTB38
Trunk predicted mass 6.24 80 65 197.0 0.92 1.1e-38 AC034102.1 AC083843.1 ACP2 ADCY3 AOC1 ARFGEF2 BOK C1QTNF4 C6orf106 CD79B CDC14B CDC16 CDKN2C CENPW CEP120 CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 ERGIC3 FAM136A GIPC2 GJC3 GPX1 GSDMC H1FX ICAM2 IGHMBP2 ILF3-AS1 IPO8 JMJD4 KIAA1614 LHFPL2 MRPL42 MST1P2 MTCH2 MXD3 NOA1 NOSTRIN NPIPA2 PLEKHM1P PNKD PPA2 PSMC3 QSOX2 RAB24 RAD9A RFT1 RIN3 RP11-250B2.6 RP11-361D14.2 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 SCMH1 SERPINF1 SF3A3 SLC22A4 SMARCA4 SMARCD2 SMPD2 SNAI3-AS1 SYNE1 TEAD3 TMEM43 TP53INP2 TRIM13 TRIM63 TSEN15 UBXN2A Y_RNA ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76
Standing height 9.26 114 105 318.2 0.92 1.0e-52 AC083843.1 AC103965.1 ACP2 ADCY3 ADO AOC1 ARFGEF2 ASPSCR1 BOK C1QTNF4 C6orf106 CACFD1 CD79B CDC14B CDC16 CDKN2C CDO1 CENPW CEP120 CRIPAK CSPG4P11 CTD-3076O17.1 CTNNB1 CXCR2 CYB561 DCAF16 DHDDS DIRAS3 DLEU2 DNALI1 EBPL EFEMP1 ERCC6L2 ERGIC3 ERI1 FAM136A FAM26F FAM66A FER GIPC2 GJC3 GOLGA6L4 GOLGA6L5 GPX1 GSDMC H1FX HOXB4 ICAM2 IGHMBP2 ILF3-AS1 IPO8 JAG1 JMJD4 KIAA1614 KPNA3 LHFPL2 LOXL1-AS1 LRRC37A2 MRPL42 MST1P2 MTCH2 MXD3 MYO9A NFAT5 NOA1 NOB1 NOC3L NOSTRIN NPIPA2 PCDHB5 PIAS2 PLEKHM1P PNKD PPA2 PSMC3 QSOX2 RAB24 RAD9A RFT1 RP11-250B2.6 RP11-361D14.2 RP11-382A20.2 RP11-538P18.2 RP11-640N20.1 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 SCMH1 SERPINF1 SF3A3 SLC22A4 SMARCA4 SMARCD2 SMPD2 SNAI3-AS1 SYNE1 TEAD3 TMED6 TMEM43 TP53INP2 TRIM13 TRIM63 TSEN15 U91328.21 UBXN2A Y_RNA ZBTB38 ZCCHC24 ZHX2 ZNF408 ZNF500 ZNF76 ZSCAN2
Tense / 'highly strung' 1.29 2 1 3.0 0.00 1.0e+00 ERI1 RP11-196G11.2
Seen doctor (GP) for nerves, anxiety, tension or depression 1.42 1 0 0.0 0.00 1.0e+00 U91328.21
Hair/balding pattern: Pattern 4 2.28 7 6 18.2 -0.23 6.2e-01 C10orf11 CENPW CTB-36H16.2 CTNNB1 FAM136A LRRC37A2 ZBTB38
Birth weight of first child 2.80 13 8 24.2 0.90 6.0e-06 AC034102.1 ARFGEF2 ASPSCR1 DCAF16 GJC3 IPO8 NOC3L PPA2 RP11-361D14.2 RP11-78I14.1 TEAD3 ZBTB38 ZNF76
Peak expiratory flow (PEF) 6.50 54 24 72.7 0.97 1.7e-35 ADAM19 ARFGEF2 ASPSCR1 BOK C10orf11 C1GALT1 C6orf106 CACFD1 CD79B CDC123 CDC14B CDKN2C CTA-85E5.10 DCAF16 DHDDS DLEU2 DNALI1 DPP3 EFEMP1 ERGIC3 ERI1 FAM168A FAM66A GIPC2 GSDMC HTR4 LOXL1-AS1 LRRC37A2 MDM4 METAP2 NOA1 NOSTRIN NPIPA2 NUDT5 PCGF2 PDE12 PNKD PPA2 RAD9A RNF123 RP11-361D14.2 RP11-640N20.1 SF3A3 SMPD2 SPINK9 SYNE1 THSD4 TP53INP2 TRIM13 TRIM63 UBXN2A Y_RNA ZHX2 ZNF76
Ever highly irritable/argumentative for 2 days 1.16 1 0 0.0 0.00 1.0e+00 GPX1
Qualifications: O levels/GCSEs or equivalent 1.21 1 0 0.0 0.00 1.0e+00 GPX1
Blood clot in the leg (DVT) 1.45 2 1 3.0 0.00 1.0e+00 CACFD1 ERGIC3
Medication: Paracetamol 1.33 3 2 6.1 0.00 1.0e+00 GPX1 LRRC37A2 U91328.21
Headache pain in last month 1.31 4 3 9.1 -0.55 4.5e-01 AC034102.1 LRRC37A2 NOA1 U91328.21
Medication for cholesterol, blood pressure or diabetes 1.58 2 0 0.0 0.00 1.0e+00 TSPY26P ZNF408
Gout (self-reported) 1.04 1 0 0.0 0.00 1.0e+00 U91328.21
Hypothyroidism/myxoedema (self-reported) 1.43 4 3 9.1 0.16 8.4e-01 AC034102.1 AHI1 ERI1 FAM66A
Medication: Amlodipine 1.36 1 1 3.0 0.00 1.0e+00 ZNF408
Medication: Ventolin 100micrograms inhaler 1.64 1 0 0.0 0.00 1.0e+00 AC034102.1
Birth weight 2.39 13 4 12.1 0.82 5.6e-04 C1QTNF4 CENPW DCAF16 MTCH2 PPA2 RFT1 RP11-361D14.2 RP11-73O6.3 SYNE1 TEAD3 UBXN2A Y_RNA ZNF76
Chronic bronchitis/emphysema (mother) 1.55 1 1 3.0 0.00 1.0e+00 PSMA4
High blood pressure (siblings) 1.36 1 0 0.0 0.00 1.0e+00 RP11-196G11.2
Forced vital capacity (FVC), Best measure 11.32 150 117 354.5 0.98 2.5e-113 ABHD12 AC034102.1 AC073834.3 AC083843.1 AC103965.1 ACP2 ADCY3 ADO AHI1 ANGPTL1 AOC1 ARFGEF2 ASPSCR1 BOK C10orf11 C1GALT1 C1QTNF4 C6orf106 CACFD1 CARS2 CD79B CDC123 CDC14B CDC16 CDKN2C CDO1 CENPW CEP120 CLUAP1 CRIPAK CSPG4P11 CTA-85E5.10 CTB-36H16.2 CTD-3076O17.1 CTNNB1 CTSS CXCR2 CYB561 DARS DCAF16 DHDDS DIRAS3 DLEU2 DNAJC9-AS1 DNALI1 DPP3 EBPL EFEMP1 ERCC6L2 ERGIC3 FAM136A FAM26F FBLN7 FER GALNT12 GIPC2 GOLGA6L5 GPX1 GSDMC GSTCD H1FX HOXB4 HTR4 ICAM2 IGHMBP2 ILF3-AS1 INTS12 IPO8 JAG1 JMJD4 KIAA1614 LHFPL2 LOC80154 LONRF2 LOXL1-AS1 LRPAP1 LRRC37A2 MDM4 MICAL3 MRPL42 MST1P2 MTCH2 MXD3 MYO9A NFAT5 NOA1 NOB1 NOC3L NOSTRIN NPIPA2 NUDT5 PCDHB5 PDE12 PIAS2 PLEKHM1P PNKD PPA2 PSMA4 PSMC3 QSOX2 RAB24 RAD9A RFT1 RIN3 RNF123 ROM1 RP11-152F13.7 RP11-196G11.2 RP11-250B2.6 RP11-361D14.2 RP11-382A20.2 RP11-538P18.2 RP11-574K11.5 RP11-640N20.1 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 SCMH1 SCUBE2 SEC24C SERPINF1 SF3A3 SMARCA4 SMARCD2 SMPD2 SNAI3-AS1 SYNE1 SYNM TEAD3 TMED6 TMEM43 TP53INP2 TPD52L2 TRIM13 TRIM38 TRIM63 TSEN15 U91328.21 UBXN2A WHAMM Y_RNA ZBTB38 ZCCHC24 ZHX2 ZNF408 ZNF438 ZNF500 ZNF76
Body fat percentage 3.02 35 23 69.7 -0.44 4.1e-03 ABHD12 AC073834.3 AC103965.1 ACP2 ADCY3 ARFGEF2 C1QTNF4 C6orf106 CD79B CDC14B CENPW CTD-3076O17.1 DARS DCAF16 ERI1 GOLGA6L4 GOLGA6L5 GPX1 HTR4 LRRC37A2 MTCH2 NOB1 PSMC3 RIN3 ROM1 RP11-196G11.2 RP11-78I14.1 SYNM TEAD3 TPD52L2 TRIM38 Y_RNA ZBTB38 ZNF408 ZSCAN2
Leg fat percentage (right) 3.05 33 17 51.5 -0.79 4.4e-09 ABHD12 AC073834.3 ACP2 ADCY3 ARFGEF2 C1QTNF4 C6orf106 CD79B CDC14B CENPW DARS DCAF16 ERGIC3 ERI1 GOLGA6L4 GPX1 HTR4 MTCH2 NOB1 PLEKHM1P PSMC3 RFT1 RIN3 RP11-196G11.2 SMARCD2 SNAI3-AS1 SYNM TEAD3 TMED6 TPD52L2 TRIM38 Y_RNA ZNF408
Arm fat-free mass (right) 5.07 65 54 163.6 0.90 4.1e-27 AC034102.1 AC083843.1 ACP2 AOC1 ARFGEF2 BOK C6orf106 CD79B CDC14B CDC16 CDKN2C CENPW CEP120 CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 ERGIC3 GIPC2 GPX1 GSDMC H1FX IGHMBP2 ILF3-AS1 IPO8 JMJD4 KIAA1614 LHFPL2 MRPL42 MXD3 NOSTRIN NPIPA2 PNKD PPA2 RAB24 RAD9A RIN3 RP11-196G11.2 RP11-250B2.6 RP11-361D14.2 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 SCMH1 SERPINF1 SF3A3 SLC22A4 SMARCA4 SMARCD2 SMPD2 SYNE1 TEAD3 TP53INP2 TRIM13 TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZHX2 ZNF76
Comparative body size at age 10 2.45 12 8 24.2 -0.91 7.2e-06 ACP2 ADCY3 C1QTNF4 ERI1 FAM66A GOLGA6L4 MTCH2 MYO9A PSMC3 RP11-196G11.2 U91328.21 Y_RNA
Number of full brothers 1.12 1 0 0.0 0.00 1.0e+00 LRRC37A2
Worry too long after embarrassment 1.51 4 0 0.0 0.30 7.0e-01 AHI1 ERI1 LRRC37A2 PPA2
Wheeze or whistling in the chest in last year 2.11 3 0 0.0 0.00 1.0e+00 ADAM19 GPX1 TPD52L2
Age at first live birth 1.39 2 1 3.0 0.00 1.0e+00 AC034102.1 GPX1
Qualifications: College or University degree 1.76 7 6 18.2 0.80 1.7e-02 AC034102.1 GPX1 LRRC37A2 MDM4 PPA2 RNF123 SMARCD2
Medication for pain relief, constipation, heartburn 1.42 2 1 3.0 0.00 1.0e+00 LRRC37A2 U91328.21
Neck or shoulder pain in last month 1.05 1 0 0.0 0.00 1.0e+00 GPX1
Medication: Blood pressure 1.71 4 2 6.1 -1.00 2.0e-03 CDC16 ERI1 TSPY26P ZNF408
Medication: Seretide 50 evohaler 1.48 1 0 0.0 0.00 1.0e+00 SLC22A4
Mean time to correctly identify matches 1.19 2 1 3.0 0.00 1.0e+00 LRRC37A2 SCUBE2
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.97 1 0 0.0 0.00 1.0e+00 LRRC37A2
Whole body fat mass 2.64 33 26 78.8 0.12 4.9e-01 ABHD12 AC034102.1 AC103965.1 ACP2 ADCY3 C1QTNF4 C6orf106 CEP120 CTD-3076O17.1 CTNNB1 EFEMP1 ERGIC3 ERI1 GOLGA6L4 GOLGA6L5 GPX1 HTR4 LRRC37A2 MTCH2 NOB1 PSMC3 RAD9A RP11-196G11.2 RP11-361D14.2 RP11-73O6.3 RP11-78I14.1 SYNM TP53INP2 TPD52L2 TRIM38 Y_RNA ZBTB38 ZSCAN2
Leg fat mass (right) 2.36 27 16 48.5 -0.21 2.7e-01 ABHD12 AC034102.1 ACP2 ADCY3 C1QTNF4 C6orf106 CEP120 CTNNB1 DARS ERI1 GIPC2 GOLGA6L4 GPX1 HTR4 MTCH2 NOB1 PSMC3 RAD9A RP11-196G11.2 RP11-73O6.3 RP11-78I14.1 SYNM TPD52L2 TRIM38 Y_RNA ZBTB38 ZSCAN2
Arm predicted mass (right) 5.02 67 51 154.5 0.90 7.7e-27 AC034102.1 AC083843.1 ACP2 AOC1 ARFGEF2 BOK C6orf106 CD79B CDC14B CDC16 CDKN2C CENPW CEP120 CRIPAK CTNNB1 CXCR2 DCAF16 DHDDS DLEU2 EBPL EFEMP1 ERGIC3 GIPC2 GPX1 GSDMC H1FX IGHMBP2 ILF3-AS1 IPO8 JMJD4 KIAA1614 LHFPL2 MRPL42 MXD3 NOSTRIN NPIPA2 PNKD PPA2 RAB24 RAD9A RIN3 RP11-196G11.2 RP11-250B2.6 RP11-361D14.2 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 SCMH1 SERPINF1 SF3A3 SLC22A4 SMARCA4 SMARCD2 SMPD2 SYNE1 TEAD3 TP53INP2 TRIM13 TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76
Pulse rate, automated reading 1.42 11 6 18.2 -0.43 1.8e-01 AC034102.1 AC103965.1 C6orf106 CDC14B CEP120 CTNNB1 DARS PCGF2 ROM1 RP11-382A20.2 ZBTB38
Alcohol intake frequency. 1.63 9 7 21.2 -0.81 4.1e-03 AC034102.1 C1QTNF4 LRRC37A2 MTCH2 PPA2 PSMC3 TMED6 UBXN2A Y_RNA
Comparative height size at age 10 7.67 85 70 212.1 0.91 9.9e-38 AC103965.1 ACP2 ADCY3 AOC1 ARFGEF2 ASPSCR1 BOK C1QTNF4 C6orf106 CD79B CDC14B CDC16 CDKN2C CDO1 CENPW CEP120 CRIPAK CSPG4P11 CTD-3076O17.1 CTNNB1 CXCR2 DCAF16 DHDDS DLEU2 EBPL EFEMP1 ERGIC3 FAM136A FAM26F FER GOLGA6L4 GOLGA6L5 GSDMC H1FX HOXB4 ICAM2 ILF3-AS1 IPO8 JMJD4 KIAA1614 LHFPL2 LOXL1-AS1 LRRC37A2 MICAL3 MRPL42 MST1P2 MTCH2 MTMR3 MXD3 MYO9A PLEKHM1P PNKD PPA2 PSMC3 QSOX2 RAB24 RAD9A RFT1 RP11-250B2.6 RP11-361D14.2 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 SCMH1 SERPINF1 SF3A3 SLC22A4 SMARCD2 SMPD2 SYNE1 TEAD3 TMEM43 TP53INP2 TRIM13 TRIM63 TSEN15 U91328.21 UBXN2A Y_RNA ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76 ZSCAN2
Suffer from 'nerves' 1.83 6 4 12.1 0.55 2.6e-01 ACP2 C1QTNF4 LRRC37A2 MTCH2 PSMC3 Y_RNA
Overall health rating 1.61 6 3 9.1 -0.93 7.0e-03 DCAF16 DPP3 ERI1 GPX1 HTR4 RP11-196G11.2
Age at last live birth 1.24 1 1 3.0 0.00 1.0e+00 GPX1
Knee pain experienced in last month 1.54 2 0 0.0 0.00 1.0e+00 ERGIC3 RP11-196G11.2
Hypertension (Self-reported) 1.88 17 5 15.2 -0.94 1.4e-09 ACP2 ARFGEF2 C1GALT1 CDC16 DCAF16 ERI1 FAM66A HTR4 NFAT5 PSMC3 RP11-196G11.2 RP11-538P18.2 SLC22A4 TSPY26P U91328.21 ZNF408 ZNF500
Forced expiratory volume in 1-second (FEV1), predicted 6.90 51 31 93.9 0.97 9.7e-37 AC103965.1 ACP2 ADCY3 BOK C1QTNF4 C6orf106 CD79B CDC16 CDKN2C CENPW CSPG4P11 CTD-3076O17.1 DCAF16 DLEU2 EBPL EFEMP1 ERGIC3 FER GOLGA6L4 GOLGA6L5 GSDMC H1FX HOXB4 ILF3-AS1 JMJD4 LOXL1-AS1 MRPL42 MST1P2 MTCH2 NOSTRIN PSMC3 RAB24 RAD9A RFT1 RP11-361D14.2 RP11-690I21.1 RP11-73O6.3 RP11-977G19.11 SCMH1 SF3A3 SLC22A4 SMARCD2 TEAD3 TP53INP2 TSEN15 Y_RNA ZBTB38 ZHX2 ZNF500 ZNF76 ZSCAN2
Whole body fat-free mass 5.46 70 61 184.8 0.92 1.2e-32 AC034102.1 AC083843.1 ACP2 AOC1 ARFGEF2 BOK C6orf106 CD79B CDC14B CDC16 CDKN2C CENPW CEP120 CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 ERGIC3 GIPC2 GPX1 GSDMC H1FX IGHMBP2 ILF3-AS1 IPO8 JMJD4 KIAA1614 LHFPL2 MRPL42 MXD3 NOSTRIN NPIPA2 PLEKHM1P PNKD PPA2 PSMC3 QSOX2 RAB24 RAD9A RIN3 RP11-250B2.6 RP11-361D14.2 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 SCMH1 SERPINF1 SF3A3 SLC22A4 SMARCA4 SMARCD2 SMPD2 SNAI3-AS1 SYNE1 TEAD3 TMEM43 TP53INP2 TRIM13 TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76
Leg fat-free mass (right) 4.38 61 43 130.3 0.90 1.1e-24 AC034102.1 AC083843.1 AOC1 BOK C6orf106 CD79B CDC14B CDC16 CDKN2C CENPW CEP120 CRIPAK CTNNB1 DCAF16 DLEU2 EBPL EFEMP1 ERGIC3 ERI1 GIPC2 GPX1 GSDMC H1FX IGHMBP2 ILF3-AS1 IPO8 JMJD4 KIAA1614 LHFPL2 MRPL42 MXD3 NOSTRIN NPIPA2 PLEKHM1P PNKD PPA2 QSOX2 RAD9A RIN3 RP11-250B2.6 RP11-361D14.2 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 SCMH1 SF3A3 SLC22A4 SMARCA4 SMARCD2 SMPD2 SNAI3-AS1 SYNE1 TP53INP2 TRIM13 TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZNF500 ZNF76
Arm fat percentage (left) 3.01 29 15 45.5 -0.70 9.3e-06 ABHD12 ACP2 ADCY3 ARFGEF2 C1QTNF4 C6orf106 CD79B CENPW DARS DCAF16 DPP3 ERI1 GPX1 HTR4 LRRC37A2 MTCH2 NFAT5 NOB1 PSMC3 RP11-196G11.2 RP11-78I14.1 RP11-967K21.1 SYNM TEAD3 TPD52L2 TRIM38 Y_RNA ZNF408 ZNF76
Handedness (chirality/laterality): Left-handed 1.23 1 1 3.0 0.00 1.0e+00 LRRC37A2
Mood swings 1.45 3 2 6.1 0.00 1.0e+00 GPX1 LRRC37A2 MTCH2
Loneliness, isolation 1.53 5 1 3.0 0.64 2.5e-01 C1QTNF4 GPX1 MTCH2 PSMC3 Y_RNA
Long-standing illness, disability or infirmity 1.35 1 0 0.0 0.00 1.0e+00 NOB1
Diabetes diagnosed by doctor 1.75 3 0 0.0 0.00 1.0e+00 C1GALT1 CENPW NOB1
Qualifications: nursing, teaching 1.38 2 0 0.0 0.00 1.0e+00 GPX1 PIAS2
Mouth/teeth dental problems: Mouth ulcers 1.21 2 2 6.1 0.00 1.0e+00 CTSS LRRC37A2
Medication for cholesterol 1.70 1 0 0.0 0.00 1.0e+00 ZNF500
Mineral and other dietary supplements 1.16 1 0 0.0 0.00 1.0e+00 NFAT5
Asthma (self-reported) 2.45 10 7 21.2 -0.92 4.8e-05 AC034102.1 ADAM19 AHI1 HTR4 RP11-574K11.5 SLC22A4 TPD52L2 TRIM38 U91328.21 ZNF76
Smoking status: Current 1.54 3 0 0.0 0.00 1.0e+00 FAM66A MTCH2 TPD52L2
Forced expiratory volume in 1-second (FEV1), predicted percentage 6.71 53 30 90.9 0.98 2.5e-40 ABHD12 AC073834.3 ADAM19 ADO ANGPTL1 ASPSCR1 BOK C10orf11 C1GALT1 CDC123 CEP120 CLUAP1 CTA-85E5.10 CTSS DHDDS ERI1 FAM168A GM2A GSTCD HTR4 INTS12 JAG1 LRRC37A2 MICAL3 NNT NOB1 NUDT5 PCGF2 PDE12 PPA2 PSMA4 QSOX2 RIN3 RNF123 ROM1 RP11-152F13.7 RP11-196G11.2 RP11-250B2.6 RP11-361D14.2 RP11-382A20.2 RP11-538P18.2 RP11-967K21.1 SEC24C SMPD2 SOGA2 SPINK9 THSD4 TPD52L2 TRIM38 TRIM63 U91328.21 WHAMM ZNF76
Whole body water mass 5.42 69 59 178.8 0.92 2.0e-31 AC034102.1 AC083843.1 ACP2 AOC1 ARFGEF2 BOK C6orf106 CD79B CDC14B CDC16 CDKN2C CENPW CEP120 CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 ERGIC3 GIPC2 GPX1 GSDMC H1FX IGHMBP2 ILF3-AS1 IPO8 JMJD4 KIAA1614 LHFPL2 MRPL42 MXD3 NOSTRIN NPIPA2 PNKD PPA2 PSMC3 QSOX2 RAB24 RAD9A RIN3 RP11-250B2.6 RP11-361D14.2 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 SCMH1 SERPINF1 SF3A3 SLC22A4 SMARCA4 SMARCD2 SMPD2 SNAI3-AS1 SYNE1 TEAD3 TMEM43 TP53INP2 TRIM13 TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76
Leg predicted mass (right) 4.39 63 43 130.3 0.90 2.1e-25 AC034102.1 AC083843.1 AOC1 ARFGEF2 BOK C6orf106 CD79B CDC14B CDC16 CDKN2C CENPW CEP120 CRIPAK CTNNB1 DCAF16 DLEU2 EBPL EFEMP1 ERGIC3 ERI1 GIPC2 GPX1 GSDMC H1FX IGHMBP2 ILF3-AS1 IPO8 JMJD4 KIAA1614 LHFPL2 MRPL42 MXD3 NOSTRIN NPIPA2 PLEKHM1P PNKD PPA2 QSOX2 RAD9A RIN3 RP11-250B2.6 RP11-361D14.2 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 SCMH1 SF3A3 SLC22A4 SMARCA4 SMARCD2 SMPD2 SNAI3-AS1 SYNE1 TP53INP2 TRIM13 TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76
Arm fat mass (left) 2.32 26 17 51.5 -0.22 2.6e-01 ABHD12 AC034102.1 ACP2 ADCY3 C1QTNF4 C6orf106 CEP120 CTNNB1 ERGIC3 ERI1 FAM66A GOLGA6L4 GPX1 HTR4 MTCH2 NOB1 PSMC3 RAD9A RP11-196G11.2 RP11-73O6.3 RP11-78I14.1 TP53INP2 TPD52L2 TRIM38 Y_RNA ZBTB38
Number of self-reported non-cancer illnesses 1.56 1 0 0.0 0.00 1.0e+00 SLC22A4
Miserableness 1.39 6 2 6.1 -0.27 6.1e-01 ERI1 GPX1 LRRC37A2 MTCH2 Y_RNA ZNF408
Guilty feelings 1.42 1 0 0.0 0.00 1.0e+00 UBXN2A
Financial situation satisfaction 1.34 1 1 3.0 0.00 1.0e+00 GPX1
Medication: Blood pressure 1.68 5 2 6.1 -1.00 3.6e-07 ACP2 C1GALT1 ERI1 FAM66A ZNF500
Supplements: Fish oil (including cod liver oil) 1.39 1 0 0.0 0.00 1.0e+00 NFAT5
High cholesterol (Self-reported) 1.49 3 1 3.0 0.00 1.0e+00 FAM136A RP11-196G11.2 SMARCA4
Medication: Bendroflumethiazide 1.47 1 0 0.0 0.00 1.0e+00 ERI1
Medication: Paracetamol 1.29 3 1 3.0 0.00 1.0e+00 GPX1 LRRC37A2 U91328.21
Illnesses of father: High blood pressure 1.28 1 0 0.0 0.00 1.0e+00 CDC16
Alcohol drinker status: Never 1.33 1 0 0.0 0.00 1.0e+00 Y_RNA
Ever smoked 1.26 3 0 0.0 0.00 1.0e+00 CTNNB1 NOA1 PSMA4
Basal metabolic rate 4.95 68 55 166.7 0.89 4.9e-26 AC034102.1 AC083843.1 AOC1 ARFGEF2 BOK C6orf106 CD79B CDC14B CDC16 CDKN2C CENPW CEP120 CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 ERGIC3 ERI1 GIPC2 GPX1 GSDMC H1FX IGHMBP2 ILF3-AS1 IPO8 JMJD4 KIAA1614 LHFPL2 MRPL42 MXD3 NOSTRIN NPIPA2 PNKD PPA2 QSOX2 RAB24 RAD9A RIN3 RP11-196G11.2 RP11-250B2.6 RP11-361D14.2 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 SCMH1 SERPINF1 SF3A3 SLC22A4 SMARCA4 SMARCD2 SMPD2 SYNE1 TEAD3 TP53INP2 TRIM13 TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76 ZSCAN2
Leg fat percentage (left) 3.07 32 19 57.6 -0.79 6.7e-09 ABHD12 AC073834.3 ACP2 ADCY3 ARFGEF2 C1QTNF4 C6orf106 CD79B CDC14B CENPW DARS DCAF16 ERI1 GOLGA6L4 GPX1 HTR4 MTCH2 NOB1 PLEKHM1P PSMC3 RFT1 RIN3 RP11-196G11.2 SMARCD2 SYNM TEAD3 TPD52L2 TRIM38 UBXN2A Y_RNA ZNF408 ZNF76
Arm fat-free mass (left) 4.96 66 52 157.6 0.90 1.5e-26 AC034102.1 AC083843.1 ACP2 AOC1 ARFGEF2 BOK C6orf106 CD79B CDC14B CDC16 CDKN2C CENPW CEP120 CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 ERGIC3 GIPC2 GPX1 GSDMC H1FX IGHMBP2 ILF3-AS1 IPO8 JMJD4 KIAA1614 LHFPL2 MRPL42 MXD3 NOSTRIN NPIPA2 PNKD PPA2 RAB24 RAD9A RIN3 RP11-196G11.2 RP11-250B2.6 RP11-361D14.2 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 SCMH1 SERPINF1 SF3A3 SLC22A4 SMARCA4 SMARCD2 SMPD2 SYNE1 TEAD3 TP53INP2 TRIM13 TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76
Number of operations (self-reported) 1.47 1 1 3.0 0.00 1.0e+00 PPA2
Average weekly beer plus cider intake 1.47 1 0 0.0 0.00 1.0e+00 RNF123
Irritability 1.46 4 1 3.0 0.32 6.8e-01 ERI1 FAM66A LRRC37A2 RP11-196G11.2
Ever had prostate specific antigen (PSA) test 1.29 1 0 0.0 0.00 1.0e+00 ZBTB38
Fractured/broken bones in last 5 years 1.27 2 0 0.0 0.00 1.0e+00 CRIPAK LRRC37A2
Age started oral contraceptive pill 1.18 1 0 0.0 0.00 1.0e+00 GPX1
Diastolic blood pressure, automated reading 2.01 18 12 36.4 -0.27 2.8e-01 ADO CEP120 CTNNB1 DARS DCAF16 ERI1 FAM66A GPX1 JAG1 MICAL3 PDE12 RP11-196G11.2 RP11-538P18.2 SCMH1 THSD4 U91328.21 ZNF408 ZNF76
Myopia 1.78 3 1 3.0 0.00 1.0e+00 ACP2 C1QTNF4 QSOX2
Vascular/heart problems diagnosed by doctor 1.83 13 6 18.2 0.95 1.1e-07 ACP2 C1GALT1 DCAF16 ERI1 FAM66A NFAT5 RP11-196G11.2 RP11-538P18.2 SLC22A4 TEAD3 TSPY26P ZNF408 ZNF500
Cholesterol lowering medication 1.48 1 0 0.0 0.00 1.0e+00 RP11-196G11.2
Pain experienced in last month 1.40 5 1 3.0 0.76 1.4e-01 AC034102.1 CENPW GPX1 LRRC37A2 RP11-196G11.2
Deep venous thrombosis (DVT) (self-reported) 1.38 2 1 3.0 0.00 1.0e+00 CACFD1 ERGIC3
Heart disease (siblings) 1.16 1 0 0.0 0.00 1.0e+00 TP53INP2
Pack years of smoking 2.45 3 1 3.0 0.00 1.0e+00 CYB561 GPX1 PSMA4
Impedance of whole body 2.46 34 25 75.8 0.15 3.9e-01 AC034102.1 AC083843.1 AC103965.1 ADCY3 AOC1 CD79B CENPW CEP120 CSPG4P11 CTD-3076O17.1 EFEMP1 ERGIC3 ERI1 FAM66A GOLGA6L4 GOLGA6L5 GPX1 IGHMBP2 LOXL1-AS1 LRRC37A2 MRPL42 MST1P2 NNT PPA2 RAB24 RAD9A RFT1 RIN3 ROM1 RP11-382A20.2 RP11-73O6.3 SCMH1 SMPD2 ZSCAN2
Leg fat mass (left) 2.33 26 18 54.5 -0.25 2.0e-01 ABHD12 AC034102.1 ACP2 ADCY3 C1QTNF4 C6orf106 CEP120 DARS ERI1 GIPC2 GOLGA6L4 GPX1 HTR4 MTCH2 NOB1 PSMC3 RAD9A RP11-196G11.2 RP11-73O6.3 RP11-78I14.1 SYNM TPD52L2 TRIM38 Y_RNA ZBTB38 ZSCAN2
Arm predicted mass (left) 4.91 65 51 154.5 0.89 4.6e-25 AC034102.1 AC083843.1 AOC1 ARFGEF2 BOK C6orf106 CD79B CDC14B CDC16 CDKN2C CENPW CEP120 CRIPAK CTNNB1 DCAF16 DHDDS DLEU2 EBPL EFEMP1 ERGIC3 GIPC2 GPX1 GSDMC H1FX IGHMBP2 ILF3-AS1 IPO8 JMJD4 KIAA1614 LHFPL2 MRPL42 MXD3 NOSTRIN NPIPA2 PNKD PPA2 RAB24 RAD9A RIN3 RP11-196G11.2 RP11-250B2.6 RP11-361D14.2 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 SCMH1 SERPINF1 SF3A3 SLC22A4 SMARCA4 SMARCD2 SMPD2 SYNE1 TEAD3 TP53INP2 TRIM13 TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF76

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 54 1.547 3.27
GTEx Adipose Visceral Omentum 33 1.621 3.51
GTEx Adrenal Gland 16 1.098 3.15
GTEx Artery Aorta 41 1.377 3.50
GTEx Artery Coronary 21 1.775 3.78
GTEx Artery Tibial 47 1.250 3.29
GTEx Brain Caudate basal ganglia 10 1.087 3.27
GTEx Brain Cerebellar Hemisphere 21 1.410 3.54
GTEx Brain Cerebellum 23 1.160 3.45
GTEx Brain Cortex 24 2.319 3.74
GTEx Brain Frontal Cortex BA9 13 1.407 3.63
GTEx Brain Hippocampus 9 1.718 3.57
GTEx Brain Hypothalamus 14 2.373 3.88
GTEx Brain Nucleus accumbens basal ganglia 15 1.734 3.79
GTEx Brain Putamen basal ganglia 7 1.122 3.33
GTEx Breast Mammary Tissue 32 1.621 3.56
GTEx Breast Mammary Tissue (Male) 26 2.179 3.87
GTEx Breast Mammary Tissue (Female) 26 1.582 3.37
GTEx Cells EBV-transformed lymphocytes 28 1.968 3.73
GTEx Cells Transformed fibroblasts 55 1.310 3.26
GTEx Colon Sigmoid 23 1.573 3.57
GTEx Colon Transverse 30 1.453 3.44
GTEx Esophagus Gastroesophageal Junction 27 1.869 3.61
GTEx Esophagus Mucosa 51 1.536 3.42
GTEx Esophagus Muscularis 52 1.609 3.54
GTEx Heart Atrial Appendage 28 1.773 3.66
GTEx Heart Left Ventricle 22 1.438 3.51
GTEx Liver 14 1.953 3.45
GTEx Lung 48 1.671 3.40
GTEx Muscle Skeletal 34 1.176 3.29
GTEx Nerve Tibial 66 1.527 3.27
GTEx Ovary 18 1.982 4.20
GTEx Pancreas 26 1.593 3.44
GTEx Pituitary 26 2.332 3.65
GTEx Prostate 14 1.677 3.47
GTEx Skin Not Sun Exposed Suprapubic 43 1.749 3.39
GTEx Skin Sun Exposed Lower leg 57 1.566 3.46
GTEx Small Intestine Terminal Ileum 9 1.952 3.98
GTEx Spleen 21 1.488 3.54
GTEx Stomach 24 1.651 3.56
GTEx Testis 44 1.395 3.46
GTEx Thyroid 56 1.400 3.35
GTEx Uterus 9 1.587 4.11
GTEx Vagina 10 1.575 3.55
GTEx Whole Blood 33 1.656 3.25
METSIM Adipose 33 0.716 2.80
NTR Blood 20 0.833 2.84
ROSMAP Brain Pre-frontal Cortex 36 0.820 2.90
YFS Blood 43 0.931 2.77
CommonMind Brain Pre-frontal Cortex 50 0.930 2.80
TCGA Breast Tumor 12 1.565 3.37
TCGA Breast Normal 41 0.975 2.58
TCGA Ovarian Tumor 36 1.232 2.88
TCGA Prostate Tumor 33 0.954 2.89