Hub : Traits :

Pulse rate, automated reading

1660 significantly associated models · 446 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 5611729 7016109 1 1 5.0e-09 9.0e-18 1.2e-10 44 GPR153
2 1 25615377 26988026 1 1 2.9e-07 1.8e-09 4.9e-04 66 PAFAH2
3 1 28011854 29594563 3 1 6.1e-09 1.6e-08 3.5e-02 86 SNHG12
4 1 39258674 40737589 4 1 1.8e-10 5.8e-09 5.0e-01 99 PABPC4
5 1 44548410 46844530 7 2 1.5e-09 2.3e-42 6.2e-40 6 GPBP1L1 ZSWIM5
6 1 66304567 67944069 2 2 2.0e-17 5.0e-25 8.3e-09 69 SGIP1 TCTEX1D1
7 1 71163715 73435171 1 1 2.4e-08 9.4e-09 4.9e-04 63 NEGR1
8 1 86684713 88329338 2 2 3.7e-14 2.2e-22 3.5e-12 49 HS2ST1 LOC339524
9 1 155739430 157406190 2 2 8.1e-09 3.4e-12 1.1e-03 78 MEF2D MRPL24
10 1 172881827 175860452 4 2 1.7e-11 3.3e-09 1.4e-02 83 ANKRD45 KIAA0040
11 1 201099275 202607593 4 1 2.2e-10 3.9e-09 9.2e-01 100 IPO9
12 1 206802184 208664733 2 2 1.9e-12 2.1e-51 2.3e-41 20 CD46 CD55
13 1 236160141 237625236 1 1 2.1e-09 2.8e-07 5.7e-01 99 ACTN2
14 2 16998604 18537483 2 2 2.4e-10 1.2e-15 3.9e-03 87 RAD51AP2 VSNL1
15 2 26653457 28607344 13 2 3.3e-17 1.2e-27 6.0e-03 94 AC074117.10 NRBP1
16 2 47224927 48727280 1 1 3.2e-09 8.8e-10 9.9e-03 82 MSH6
17 2 53395138 54976770 2 1 1.6e-07 3.8e-08 4.9e-02 87 HMGB1P31
18 2 64168232 65573478 1 1 2.2e-07 5.6e-06 8.7e-03 67 SERTAD2
19 2 135972093 137435625 1 1 8.2e-08 3.0e-08 1.0e+00 100 DARS
20 2 162433413 163867706 1 1 3.9e-07 1.9e-10 1.5e-05 54 IFIH1
21 2 178280031 180825685 9 10 6.2e-20 2.4e-117 NaN NaN AC009948.5 FKBP7 OSBPL6 PRKRA RBM45 RP11-171I2.5 SESTD1 TTN TTN-AS1
22 2 186863405 189122229 4 1 2.2e-24 2.5e-24 1.0e+00 100 CALCRL
23 2 190357442 192254289 6 1 2.5e-11 4.5e-11 5.5e-02 92 MFSD6
24 2 200134004 202036478 2 1 1.9e-09 8.6e-13 7.9e-05 70 C2orf47
25 2 219399627 221058583 3 2 1.2e-13 1.0e-29 5.2e-18 42 GLB1L RP11-316O14.1
26 2 227498520 228912778 1 1 1.6e-13 4.8e-12 7.3e-01 100 MFF
27 2 231564626 234168951 3 2 7.5e-22 3.2e-23 1.0e+00 100 B3GNT7 EIF4E2
28 3 14781364 16261420 2 1 3.4e-11 3.9e-10 1.7e-03 75 COLQ
29 3 40537829 41986787 1 1 5.5e-08 5.9e-08 1.1e-01 91 CTNNB1
30 3 46919379 51077419 44 7 1.4e-28 1.5e-26 NaN NaN AMT CSPG5 MST1 RBM6 TRAIP
31 3 51306844 54077726 12 8 1.1e-15 4.9e-17 NaN NaN DCP1A GNL3 NEK4 RP11-155D18.12 TKT TMEM110
32 3 65739897 67250048 1 1 1.1e-08 8.4e-11 1.7e-03 76 LRIG1
33 3 121346656 122929314 5 2 1.2e-14 2.9e-14 1.0e+00 100 CSTA WDR5B
34 3 140350567 142017527 2 1 2.4e-16 3.9e-17 1.0e+00 100 ZBTB38
35 3 178356269 179864765 4 1 4.4e-25 4.3e-25 1.0e+00 100 AC007620.3
36 3 182942402 184700426 2 1 2.7e-09 3.3e-12 2.7e-04 73 ECE2
37 4 470103 2058475 7 1 2.4e-09 4.8e-12 1.1e-05 60 MAEA
38 4 5575751 7002344 1 1 8.5e-09 4.1e-10 2.7e-03 77 WFS1
39 4 77938810 79439935 1 1 7.8e-08 1.1e-05 2.1e-01 92 CNOT6L
40 4 82578407 83991529 1 1 1.5e-07 2.1e-09 3.8e-03 77 HNRNPD
41 4 158997448 160525502 1 1 3.6e-11 6.3e-11 1.0e+00 100 FNIP2
42 5 44129083 45516364 1 1 4.5e-08 2.9e-08 1.0e-01 91 RP11-53O19.3
43 5 86867897 88427942 1 1 2.0e-09 1.1e-09 9.5e-02 92 TMEM161B-AS1
44 5 121983336 123449266 2 1 2.4e-13 1.2e-13 1.0e+00 100 CEP120
45 5 136262454 139475611 8 11 3.9e-30 3.9e-30 1.0e+00 100 DNAJC18 HNRNPA0 KLHL3 MYOT REEP2 RP11-381K20.5
46 5 171876084 173289036 1 1 1.4e-08 1.2e-16 3.3e-13 23 BNIP1
47 6 6701209 8115492 1 1 1.5e-11 4.5e-14 1.2e-07 51 RIOK1
48 6 25296606 26689223 1 1 1.7e-07 6.7e-11 2.3e-06 48 U91328.19
49 6 33856903 35549670 3 1 2.0e-11 2.8e-10 1.0e+00 100 C6orf106
50 6 36014161 37590303 3 2 9.2e-12 5.5e-23 9.0e-11 57 PPIL1
51 6 41058968 42587818 2 1 6.2e-09 1.8e-14 4.2e-12 18 MED20
52 6 53184508 54821152 1 1 7.4e-08 1.7e-13 3.5e-07 52 MLIP
53 6 105033213 106549398 1 1 8.1e-09 2.0e-09 1.0e+00 100 PREP
54 6 118089396 120041948 4 4 2.3e-56 5.1e-74 8.4e-10 89 CEP85L MCM9
55 6 120704438 123739731 3 7 9.4e-56 7.6e-109 6.0e-10 92 GJA1 PKIB TBC1D32
56 7 75059331 75803132 1 1 1.9e-07 1.8e-06 1.0e+00 100 POM121C
57 7 98244565 101185166 37 9 1.8e-82 4.7e-76 NaN NaN AP4M1 ARPC1A GATS GIGYF1 MEPCE PPP1R35 TFR2
58 7 115619298 117135212 1 1 6.2e-13 1.2e-13 1.0e+00 100 MET
59 7 122624770 124081532 2 1 6.1e-13 4.0e-14 1.0e+00 100 WASL
60 7 130101373 131880252 2 1 9.1e-12 9.7e-25 1.6e-14 44 MKLN1-AS2
61 7 134650544 136094817 3 1 1.2e-09 7.8e-09 1.1e-01 92 C7orf73
62 9 16448628 18201083 1 1 2.2e-07 9.4e-07 1.0e-01 89 CNTLN
63 9 35213538 36597142 1 1 2.8e-15 2.9e-15 1.0e+00 100 LINC00961
64 9 98302535 99734369 1 1 1.8e-07 1.1e-07 1.7e-02 80 HSD17B3
65 9 122669622 124331465 6 1 9.8e-10 1.5e-09 3.7e-01 98 RP11-27I1.4
66 9 127035761 129422783 3 1 1.8e-24 3.4e-25 7.3e-04 89 MAPKAP1
67 10 29001607 30716397 2 1 4.2e-12 3.4e-14 1.1e-16 -20 SVIL
68 10 42607692 44027356 2 1 2.5e-07 1.1e-09 7.8e-04 70 BMS1
69 10 49667361 51094660 1 1 7.0e-08 5.8e-09 4.9e-05 51 C10orf128
70 10 62473976 63907657 1 1 1.2e-08 2.2e-12 3.9e-05 66 TMEM26
71 10 74687808 76323150 9 1 5.3e-12 2.4e-10 9.0e-03 83 FUT11
72 10 100504603 103018321 7 3 6.3e-12 4.4e-12 7.2e-03 85 NDUFB8 SEC31B SLC25A28
73 10 114740745 116183647 1 1 2.7e-11 1.9e-10 3.6e-02 89 CASP7
74 11 13288698 14975818 1 1 2.9e-12 9.1e-12 1.0e+00 100 SPON1
75 11 47305669 48783497 1 1 2.8e-07 2.8e-07 2.4e-03 65 PTPRJ
76 11 56742853 58166421 1 1 1.4e-07 7.6e-07 7.3e-01 100 ZDHHC5
77 11 60465487 63110149 16 3 5.2e-38 1.3e-38 2.6e-02 97 EML3 FADS1 TMEM216
78 11 63295034 66184140 4 2 1.1e-09 1.7e-09 1.4e-03 72 FKBP2 RNASEH2C
79 11 67976812 69406625 1 1 1.6e-07 1.5e-07 5.2e-03 72 IGHMBP2
80 11 77231939 78828001 1 1 7.8e-08 1.2e-07 1.3e-01 92 GAB2
81 11 101404645 102797829 1 1 2.2e-09 2.2e-09 1.0e+00 100 RP11-864G5.3
82 12 19826892 21533355 1 1 3.6e-09 3.8e-15 4.6e-08 52 PDE3A
83 12 24273423 27168878 3 2 1.1e-15 1.3e-80 2.2e-74 8 BCAT1 SSPN
84 12 27234999 28643213 2 1 1.2e-10 7.7e-11 1.0e+00 100 RP11-860B13.1
85 12 32831091 34826574 2 3 1.9e-35 4.0e-65 1.2e-14 80 ALG10 SYT10
86 12 38044044 39998144 2 1 8.0e-15 7.0e-19 2.0e-06 71 CPNE8
87 12 48605088 50364707 8 1 1.2e-11 1.6e-08 9.9e-02 92 RP11-302B13.5
88 12 80954858 82853038 1 1 2.5e-12 4.0e-12 1.0e+00 100 PPFIA2
89 12 109591369 111699146 8 1 8.2e-12 1.4e-11 1.0e+00 100 GPN3
90 12 122318723 124162750 3 1 2.3e-12 9.9e-11 3.0e-04 69 ABCB9
91 13 41092698 42640341 2 1 2.8e-08 4.1e-08 1.0e+00 100 NAA16
92 14 20843889 22255090 1 1 9.3e-19 6.4e-32 1.3e-18 44 ARHGEF40
93 14 22670975 25605046 14 10 7.1e-79 4.0e-169 2.6e-46 73 CBLN3 HOMEZ PPP1R3E PRMT5 PSMB5 RBM23 RP11-66N24.4 SLC22A17 SLC7A8
94 14 51775331 53232305 1 1 3.1e-07 1.7e-08 1.4e-03 68 NID2
95 14 77529069 79097679 2 1 1.6e-08 5.1e-10 8.3e-06 49 C14orf178
96 14 85303548 86791228 1 1 5.5e-50 3.1e-50 1.0e+00 100 FLRT2
97 14 90643934 92390620 2 1 4.1e-13 1.6e-15 4.0e-09 46 C14orf159
98 14 101850676 103494612 2 1 7.2e-08 9.7e-09 1.7e-02 83 ZNF839
99 15 62636766 64056437 1 1 4.3e-08 1.6e-08 1.0e+00 100 TPM1
100 15 71418503 75067747 7 6 8.4e-30 3.9e-59 3.2e-33 45 CELF6 GOLGA6A HEXA MYO9A NEO1
101 15 83167559 84434423 2 3 2.4e-10 9.9e-09 3.0e-01 97 BTBD1 C15orf40
102 15 98944630 100367846 2 1 1.6e-07 3.6e-07 1.7e-01 93 RP11-6O2.4
103 16 86671 934180 1 1 2.7e-07 4.9e-05 7.6e-01 99 LA16c-OS12.2
104 16 3608256 5479168 2 2 1.4e-07 5.4e-10 1.6e-05 52 ANKS3 RP11-95P2.1
105 16 15369019 16832414 1 1 7.2e-08 1.8e-30 3.7e-26 15 ABCC1
106 16 29905882 31860399 7 1 4.4e-10 4.7e-09 9.0e-01 100 RNF40
107 16 52772129 54235440 2 1 8.3e-16 3.0e-14 9.4e-01 100 RBL2
108 16 66143181 68210165 2 2 6.4e-09 2.8e-09 2.8e-03 75 ATP6V0D1 NAE1
109 16 69323837 70794031 1 1 6.0e-08 3.3e-09 2.0e-04 60 PDXDC2
110 16 88241380 89617518 1 1 2.3e-07 2.7e-05 9.6e-04 38 TRAPPC2L
111 17 4156620 5556453 1 1 2.7e-07 5.9e-07 2.5e-01 95 ENO3
112 17 14509122 16158774 3 1 5.9e-14 4.4e-12 4.4e-09 28 TEKT3
113 17 16419425 18325085 7 3 5.1e-13 4.1e-12 7.1e-01 100 DRG2 FLCN TOM1L2
114 17 19142226 20292395 1 1 6.8e-08 8.8e-07 1.3e-02 74 SLC47A2
115 17 26716917 28172357 1 1 9.1e-08 8.3e-08 1.0e+00 100 MYO18A
116 17 36211659 37605364 1 1 8.1e-11 4.9e-10 1.0e+00 100 PCGF2
117 17 44788310 45876022 1 1 6.1e-08 1.7e-11 4.4e-05 63 RP11-156P1.3
118 17 55802620 57263393 1 1 1.3e-07 1.4e-05 6.6e-02 82 HSF5
119 17 73972187 75405078 2 1 6.9e-09 6.4e-10 3.1e-02 88 RP11-318A15.2
120 18 6067843 7614809 2 1 1.7e-07 3.4e-07 5.8e-01 99 RP11-91I8.3
121 18 25668821 27062372 1 1 3.8e-11 3.1e-17 1.2e-19 -15 RP11-510D21.1
122 18 33182828 35503998 2 2 3.0e-07 1.4e-17 3.9e-11 40 FHOD3 KIAA1328
123 19 35807727 37300554 4 1 5.5e-10 4.7e-08 4.6e-02 87 WDR62
124 19 38444944 39951086 2 1 2.4e-16 5.1e-17 1.0e-02 91 ACTN4
125 19 40000075 41953928 4 3 1.6e-13 1.8e-14 1.8e-01 97 C19orf47 C19orf54 MAP3K10
126 20 35835657 37654024 3 3 9.9e-51 4.1e-116 4.5e-53 55 KIAA1755 VSTM2L
127 20 39114404 40516054 1 1 1.6e-07 1.9e-11 9.1e-06 56 RP3-511B24.6
128 20 60781573 62912463 3 3 3.4e-09 2.7e-10 8.0e-04 72 LINC00266-1 PRPF6 TCFL5
129 22 38192452 40338284 16 1 2.5e-20 2.9e-20 1.0e+00 100 SUN2

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Alzheimer’s Disease (including proxy) 1.05 2 0 0.0 0.00 1.0e+00 GATS RNF40
Crohns Disease (2017) 1.56 6 5 15.2 0.26 5.8e-01 AC074117.10 FADS1 FUT11 MST1 RBM6 ZBTB38
Irritable Bowel Disease (IBD) 1.64 8 4 12.1 -0.57 8.5e-02 AC074117.10 AMT FUT11 GIGYF1 MST1 NRBP1 RBM6 TCTEX1D1
Ulcerative Colitis (UC) 1.38 4 3 9.1 -0.73 1.6e-01 AMT MST1 RBM6 TCTEX1D1
Major Depression (MDD) 1.71 2 2 6.1 0.00 1.0e+00 NEGR1 ZDHHC5
Reaction Time 1.28 5 0 0.0 0.63 2.5e-01 C2orf47 FKBP2 LA16c-OS12.2 RP11-302B13.5 RP11-318A15.2
Verbal and Numeric Reasoning (VNR) 1.60 8 6 18.2 0.70 2.4e-02 GNL3 MST1 NEGR1 NEK4 RBL2 RBM6 TMEM110 TOM1L2
Breast Cancer 1.29 2 2 6.1 0.00 1.0e+00 RP11-53O19.3 ZBTB38
Age at First Birth 1.40 2 1 3.0 0.00 1.0e+00 MST1 RBM6
Bipolar Disorder 1.89 3 1 3.0 0.00 1.0e+00 GNL3 NEK4 RP11-302B13.5
Body Mass Index (BMI) (2010) 1.51 2 1 3.0 0.00 1.0e+00 NEGR1 POM121C
Crohns Disease (2012) 1.46 3 2 6.1 -0.96 4.0e-02 FADS1 MST1 RBM6
Fasting Glucose 1.63 4 3 9.1 0.87 1.3e-01 AC074117.10 FADS1 NRBP1 RP3-511B24.6
HDL Cholesterol 1.85 8 5 15.2 0.46 2.1e-01 C6orf106 FADS1 GNL3 PABPC4 PDE3A PTPRJ RBM6 TPM1
LDL Cholesterol 1.18 3 1 3.0 0.00 1.0e+00 C6orf106 FADS1 TMEM216
Lupus 0.87 1 0 0.0 0.00 1.0e+00 MFSD6
Neuroticism 1.10 1 0 0.0 0.00 1.0e+00 RP11-510D21.1
Schizophrenia 1.63 7 3 9.1 -0.75 1.2e-02 GIGYF1 GNL3 NEK4 REEP2 RP11-53O19.3 TMEM110 ZDHHC5
Triglycerides 2.94 4 3 9.1 -0.98 1.6e-02 AC074117.10 FADS1 NRBP1 PABPC4
Ulcerative Colitis 1.38 2 2 6.1 0.00 1.0e+00 MST1 RBM6
Blood Eosinophil Count 0.79 14 7 21.2 0.08 7.7e-01 ABCB9 AMT CSTA DARS FADS1 GNL3 GPN3 NEK4 PTPRJ RBM6 RNF40 SLC7A8 TRAIP ZDHHC5
Blood Platelet Count 1.65 50 36 109.1 -0.47 4.5e-04 AC074117.10 ACTN4 ANKS3 AP4M1 ARPC1A BNIP1 C10orf128 C6orf106 CEP120 DNAJC18 ECE2 ENO3 FADS1 FKBP2 GIGYF1 GNL3 GOLGA6A GPBP1L1 HSD17B3 KIAA1755 LA16c-OS12.2 MEF2D MEPCE MET MRPL24 MSH6 MST1 NRBP1 PPP1R35 REEP2 RNASEH2C RNF40 RP11-27I1.4 RP11-381K20.5 RP11-864G5.3 RP11-95P2.1 RP3-511B24.6 SERTAD2 SLC47A2 SUN2 SVIL TFR2 TMEM161B-AS1 TMEM216 TPM1 VSTM2L WASL ZDHHC5 ZNF839 ZSWIM5
Blood Red Count 1.99 38 25 75.8 -0.34 2.9e-02 AMT ANKRD45 ARPC1A C6orf106 DARS ECE2 FADS1 GAB2 GATS GIGYF1 GJA1 GNL3 GPBP1L1 GPN3 HNRNPA0 HSF5 KLHL3 LA16c-OS12.2 LINC00266-1 MAPKAP1 MED20 MFF MST1 MYO9A NEK4 PABPC4 POM121C PPP1R35 RBM6 RNASEH2C RNF40 RP11-156P1.3 SERTAD2 TFR2 TMEM110 TRAIP ZBTB38 ZDHHC5
Blood White Count 1.22 27 19 57.6 0.03 8.9e-01 AC074117.10 ACTN4 ARPC1A C10orf128 C19orf54 C6orf106 CALCRL CD46 CD55 CEP120 CEP85L DRG2 ENO3 FADS1 HSD17B3 HSF5 KIAA1755 NRBP1 PTPRJ RBM6 RNF40 RP11-318A15.2 RP11-864G5.3 SVIL TCTEX1D1 TOM1L2 ZSWIM5
Heel T-Score 1.47 36 26 78.8 -0.15 3.6e-01 AMT ANKRD45 C10orf128 CALCRL CEP120 CTNNB1 DRG2 EML3 FADS1 FLCN GAB2 GIGYF1 GJA1 IGHMBP2 MAEA MEF2D MSH6 MST1 NAE1 NEGR1 PABPC4 PCGF2 PPIL1 PTPRJ RBM6 RNASEH2C RNF40 RP11-95P2.1 RP3-511B24.6 SEC31B SERTAD2 SUN2 TCTEX1D1 TRAIP ZBTB38 ZDHHC5
BMI 1.83 36 23 69.7 -0.28 8.2e-02 ABCB9 AP4M1 ARPC1A C14orf159 C6orf106 CELF6 CEP120 CSPG5 CTNNB1 DNAJC18 ECE2 FKBP2 GAB2 GNL3 GPBP1L1 GPN3 HEXA HSD17B3 HSF5 IGHMBP2 IPO9 MEF2D MST1 MYO9A NEGR1 NEK4 NEO1 PABPC4 PDXDC2 POM121C RBM6 RNF40 TMEM110 TMEM161B-AS1 TOM1L2 ZNF839
Height 1.81 63 48 145.5 0.21 9.6e-02 AC074117.10 AMT ANKRD45 ANKS3 ARHGEF40 ARPC1A B3GNT7 BNIP1 C19orf54 C6orf106 C7orf73 CALCRL CBLN3 CD46 CELF6 CEP120 CTNNB1 DNAJC18 ECE2 FADS1 GAB2 GIGYF1 GJA1 GLB1L GNL3 GOLGA6A GPBP1L1 HMGB1P31 HNRNPD HS2ST1 HSD17B3 LA16c-OS12.2 LINC00266-1 MAPKAP1 MED20 MEF2D MKLN1-AS2 MRPL24 MYO9A NRBP1 PAFAH2 PDXDC2 POM121C PRPF6 PTPRJ RBL2 REEP2 RNF40 RP11-156P1.3 RP11-171I2.5 RP11-27I1.4 RP11-316O14.1 RP11-864G5.3 RP11-95P2.1 SLC25A28 SPON1 SSPN SUN2 TCTEX1D1 TMEM26 ZBTB38 ZDHHC5 ZNF839
Waist Hip Ratio (WHR) 2.26 27 21 63.6 -0.22 2.2e-01 ALG10 AMT C14orf159 C6orf106 CALCRL CNOT6L DCP1A DRG2 EML3 FHOD3 GNL3 MAEA MEF2D NEK4 NID2 PDE3A PTPRJ RBL2 REEP2 RNASEH2C RP11-95P2.1 SLC22A17 SSPN TMEM110 TOM1L2 TRAIP ZBTB38
Systolic Blood Pressure 1.59 35 17 51.5 0.21 2.3e-01 AC074117.10 ANKS3 C2orf47 C7orf73 CD46 CSPG5 CSTA CTNNB1 DNAJC18 FUT11 GIGYF1 GNL3 GOLGA6A HOMEZ MAPKAP1 MEF2D MFSD6 MKLN1-AS2 MST1 NAA16 NRBP1 POM121C PTPRJ RNASEH2C RP11-156P1.3 RP11-510D21.1 RP3-511B24.6 SEC31B SGIP1 SLC22A17 SNHG12 TMEM161B-AS1 TPM1 WASL ZDHHC5
Smoking Status 1.50 7 4 12.1 0.42 3.0e-01 ACTN2 AMT ARPC1A CSPG5 LA16c-OS12.2 MAPKAP1 MSH6
Allergy or Eczema 1.07 7 3 9.1 -0.72 6.9e-02 AC074117.10 C6orf106 CALCRL MYOT NEGR1 NRBP1 ZBTB38
Cardiovascular Disease 1.38 13 6 18.2 -0.56 4.7e-02 AC074117.10 ANKS3 CSPG5 GOLGA6A MAPKAP1 NEGR1 NRBP1 PDXDC2 POM121C RNASEH2C RNF40 RP11-156P1.3 TMEM161B-AS1
Hypothyroidism (self reported) 1.15 3 2 6.1 0.98 2.1e-02 FADS1 GIGYF1 MFSD6
Respiratory disease 1.23 2 1 3.0 0.00 1.0e+00 FADS1 GJA1
Type 2 Diabetes (T2D) 1.71 8 6 18.2 -0.44 2.7e-01 AC074117.10 NRBP1 PABPC4 PDXDC2 RBL2 RBM6 RP11-860B13.1 WFS1
Lung FEV1/FVC ratio 1.75 36 17 51.5 0.35 3.4e-02 AP4M1 ATP6V0D1 BTBD1 C6orf106 CALCRL DCP1A DRG2 EML3 GAB2 GJA1 GLB1L GNL3 GPBP1L1 HNRNPD KIAA0040 MEF2D MET MFF MSH6 NEGR1 NEK4 NEO1 PABPC4 PCGF2 PPP1R3E RAD51AP2 RNF40 RP11-53O19.3 RP11-860B13.1 RP11-95P2.1 SERTAD2 TMEM110 TOM1L2 ZBTB38 ZDHHC5 ZSWIM5
Lung FVC 1.24 19 12 36.4 0.39 9.1e-02 ATP6V0D1 B3GNT7 BTBD1 C15orf40 C6orf106 CEP120 DARS EML3 GATS IGHMBP2 LA16c-OS12.2 MEF2D MFSD6 MSH6 RNASEH2C RP11-171I2.5 RP11-316O14.1 WDR5B ZBTB38
Neuroticism 1.35 5 1 3.0 0.03 9.6e-01 GAB2 KLHL3 SLC22A17 TMEM161B-AS1 ZDHHC5
Chronotype (morning person) 1.33 6 3 9.1 -0.53 2.8e-01 ALG10 CPNE8 HNRNPD REEP2 TMEM161B-AS1 ZDHHC5
Hair Pigment 0.40 16 10 30.3 0.12 6.1e-01 AC074117.10 BTBD1 EIF4E2 FADS1 GAB2 GIGYF1 IGHMBP2 MED20 MEPCE NRBP1 PABPC4 REEP2 RNASEH2C RP11-302B13.5 TRAPPC2L ZBTB38
Tanning 0.24 9 4 12.1 0.64 4.7e-02 AC074117.10 GAB2 GNL3 IGHMBP2 NEK4 NRBP1 TCTEX1D1 TMEM110 TRAPPC2L
Hand grip strength (left) 1.29 6 1 3.0 0.17 7.5e-01 C2orf47 DARS ECE2 MEPCE RP11-171I2.5 ZBTB38
Number of treatments/medications taken 1.35 4 1 3.0 0.57 4.3e-01 AC074117.10 ANKS3 MEF2D RBM6
Average weekly spirits intake 1.41 1 0 0.0 0.00 1.0e+00 MST1
Frequency of depressed mood in last 2 weeks 1.20 1 0 0.0 0.00 1.0e+00 ZDHHC5
Hearing difficulty/problems: Yes 1.11 2 0 0.0 0.00 1.0e+00 GPBP1L1 TTN-AS1
Relative age of first facial hair 1.36 4 2 6.1 -0.53 4.7e-01 C6orf106 MED20 MKLN1-AS2 ZBTB38
Systolic blood pressure, automated reading 1.48 12 1 3.0 -0.32 3.1e-01 GNL3 MAPKAP1 MKLN1-AS2 PDXDC2 POM121C RBM23 RNASEH2C RP11-156P1.3 SEC31B SGIP1 SLC22A17 ZDHHC5
Eye problems/disorders: Diabetes related eye disease 1.19 1 0 0.0 0.00 1.0e+00 WFS1
Medication: Co-codamol 1.17 1 0 0.0 0.00 1.0e+00 ABCB9
Medication: Metformin 1.69 4 1 3.0 0.43 5.7e-01 AC074117.10 PDXDC2 RBL2 WFS1
Pack years adult smoking proportion 1.31 1 0 0.0 0.00 1.0e+00 AMT
Impedance of leg (right) 1.52 24 18 54.5 0.25 2.3e-01 AC074117.10 ARHGEF40 C14orf159 C2orf47 C6orf106 CEP120 DNAJC18 ECE2 GNL3 HNRNPD IGHMBP2 MED20 NEGR1 NEK4 PABPC4 PDXDC2 POM121C RBL2 RBM6 RP11-302B13.5 TMEM110 TMEM161B-AS1 TOM1L2 VSTM2L
Leg fat-free mass (left) 1.91 24 18 54.5 -0.02 9.3e-01 ABCB9 AC074117.10 ARHGEF40 C14orf159 C2orf47 C6orf106 C7orf73 CEP120 CTNNB1 DNAJC18 ECE2 HSD17B3 IGHMBP2 MED20 NEGR1 PABPC4 POM121C RBL2 RBM6 RNF40 TMEM110 TMEM161B-AS1 VSTM2L ZBTB38
Trunk fat percentage 1.59 21 17 51.5 0.62 2.7e-03 ABCB9 C6orf106 CNOT6L CTNNB1 DARS EML3 FKBP2 HNRNPD MST1 NEGR1 NEO1 PABPC4 PDXDC2 POM121C RBM6 RNF40 RP11-95P2.1 RP3-511B24.6 TMEM161B-AS1 TRAIP ZBTB38
Hand grip strength (right) 1.29 8 3 9.1 -0.12 7.7e-01 C6orf106 DARS ECE2 GIGYF1 GNL3 MEPCE RP11-171I2.5 ZBTB38
Current tobacco smoking 1.20 1 1 3.0 0.00 1.0e+00 MAPKAP1
Fed-up feelings 1.46 5 1 3.0 0.99 6.1e-05 GLB1L MST1 RBM6 TMEM216 ZDHHC5
Frequency of unenthusiasm / disinterest in last 2 weeks 1.48 1 0 0.0 0.00 1.0e+00 ZDHHC5
Relative age voice broke 1.19 1 1 3.0 0.00 1.0e+00 RP11-95P2.1
Taking other prescription medications 1.36 1 1 3.0 0.00 1.0e+00 RBM6
Age when periods started (menarche) 1.70 12 9 27.3 -0.46 1.1e-01 AMT GAB2 GATS GNL3 MED20 MSH6 NEGR1 NEK4 PDXDC2 POM121C RNASEH2C TMEM110
Heel bone mineral density (BMD) T-score, automated (left) 1.39 8 5 15.2 0.53 1.8e-01 AMT IGHMBP2 MST1 RBM6 RNASEH2C SERTAD2 SUN2 TRAIP
High blood pressure 1.26 10 1 3.0 0.62 5.7e-02 ANKS3 GOLGA6A MAPKAP1 NEGR1 PDXDC2 POM121C PTPRJ RBL2 RNF40 TMEM161B-AS1
Hayfever, allergic rhinitis or eczema 1.15 6 1 3.0 0.96 2.0e-03 AC074117.10 C6orf106 CALCRL NRBP1 U91328.19 ZBTB38
Diverticular disease/diverticulitis (self-reported) 1.11 1 0 0.0 0.00 1.0e+00 SUN2
Medication: Levothyroxine sodium 1.15 2 0 0.0 0.00 1.0e+00 FADS1 MFSD6
Sitting height 1.70 29 22 66.7 -0.21 2.8e-01 AC074117.10 AMT ARHGEF40 ARPC1A C2orf47 C6orf106 C7orf73 CALCRL CEP120 CTNNB1 DNAJC18 ECE2 FADS1 GPBP1L1 HSD17B3 KIAA1755 LA16c-OS12.2 MAPKAP1 MED20 MYO9A NRBP1 PDXDC2 RBL2 RP11-156P1.3 RP11-171I2.5 RP11-95P2.1 VSTM2L ZBTB38 ZDHHC5
Body mass index (BMI) 1.78 24 14 42.4 0.19 3.5e-01 ABCB9 AC007620.3 ARPC1A C14orf159 C6orf106 CEP120 CSPG5 ECE2 FKBP2 GNL3 GPN3 IGHMBP2 IPO9 MST1 NEGR1 NEK4 PABPC4 PDXDC2 POM121C RBM6 RNF40 TMEM110 TMEM161B-AS1 U91328.19
Impedance of leg (left) 1.57 25 15 45.5 0.27 1.9e-01 AC074117.10 AMT ARHGEF40 C14orf159 C2orf47 C6orf106 CEP120 DRG2 ECE2 GNL3 HNRNPD IGHMBP2 MED20 NEGR1 NEK4 PABPC4 PDXDC2 POM121C RBL2 RBM6 RP11-302B13.5 TMEM110 TMEM161B-AS1 TOM1L2 VSTM2L
Leg predicted mass (left) 1.90 24 17 51.5 -0.02 9.3e-01 ABCB9 AC074117.10 ARHGEF40 C14orf159 C2orf47 C6orf106 C7orf73 CEP120 CTNNB1 DNAJC18 ECE2 HSD17B3 IGHMBP2 MED20 NEGR1 PABPC4 POM121C RBL2 RBM6 RNF40 TMEM110 TMEM161B-AS1 VSTM2L ZBTB38
Trunk fat mass 1.78 22 15 45.5 0.44 4.1e-02 ABCB9 ANKS3 C6orf106 CEP120 CNOT6L CTNNB1 FKBP2 HNRNPD MST1 NEGR1 NEO1 PABPC4 PDXDC2 POM121C RBM6 RNF40 RP11-95P2.1 RP3-511B24.6 TMEM161B-AS1 TRAIP U91328.19 ZBTB38
Waist circumference 1.66 17 12 36.4 0.40 9.9e-02 ABCB9 ARPC1A C6orf106 CALCRL CEP120 CNOT6L CTNNB1 NEGR1 NEO1 PABPC4 PDXDC2 POM121C RBM6 RNASEH2C RNF40 TMEM161B-AS1 ZBTB38
Number of incorrect matches in round 1.40 2 0 0.0 0.00 1.0e+00 C7orf73 IPO9
Past tobacco smoking 1.44 4 0 0.0 0.48 5.2e-01 ARPC1A CSPG5 MSH6 TMEM161B-AS1
Alcohol usually taken with meals 1.41 3 2 6.1 0.00 1.0e+00 ANKRD45 NEGR1 ZDHHC5
Nervous feelings 1.31 3 1 3.0 0.00 1.0e+00 GNL3 NEK4 TMEM110
Had menopause 1.24 2 2 6.1 0.00 1.0e+00 AC074117.10 NRBP1
Forced vital capacity (FVC) 1.25 12 8 24.2 -0.36 2.3e-01 AMT ANKS3 BTBD1 C6orf106 CEP120 CTNNB1 DARS EML3 HSD17B3 MYO9A PDXDC2 ZBTB38
Heel bone mineral density (BMD) T-score, automated (right) 1.46 9 4 12.1 0.41 2.7e-01 AMT IGHMBP2 MST1 RBM6 RNASEH2C SERTAD2 SUN2 TRAIP ZBTB38
Qualifications: None of the above 1.36 7 2 6.1 0.20 6.6e-01 AMT CSPG5 MST1 NEGR1 RBL2 RBM6 ZDHHC5
Financial difficulties in last 2 years 1.15 1 0 0.0 0.00 1.0e+00 PABPC4
Allergy 1.16 3 1 3.0 0.00 1.0e+00 C6orf106 U91328.19 ZBTB38
Diabetes (self-reported) 1.83 9 4 12.1 0.49 1.8e-01 AC074117.10 AMT NRBP1 PABPC4 PDXDC2 RBL2 RBM6 RP11-860B13.1 WFS1
Medication: Simvastatin 1.12 1 0 0.0 0.00 1.0e+00 AC074117.10
Fluid intelligence score 1.39 5 2 6.1 -0.60 2.9e-01 MST1 NEGR1 RBL2 RBM6 TOM1L2
Neuroticism score 1.20 3 1 3.0 0.00 1.0e+00 PPIL1 SLC22A17 ZDHHC5
Weight 1.94 23 17 51.5 0.20 3.6e-01 ABCB9 AC074117.10 C14orf159 C6orf106 CEP120 CTNNB1 DNAJC18 ECE2 FKBP2 GPN3 IGHMBP2 MED20 MST1 NEGR1 PABPC4 PDXDC2 POM121C RBM6 RNF40 RP11-95P2.1 TMEM161B-AS1 U91328.19 ZBTB38
Impedance of arm (right) 1.65 25 17 51.5 0.39 4.4e-02 AC074117.10 AMT C2orf47 CEP120 ECE2 EML3 FNIP2 GAB2 GNL3 GOLGA6A GPN3 HNRNPD IGHMBP2 NEGR1 NEK4 POM121C RBM6 REEP2 RP11-302B13.5 RP11-316O14.1 RP11-864G5.3 TMEM110 U91328.19 ZDHHC5 ZNF839
Arm fat percentage (right) 1.56 17 11 33.3 0.73 9.1e-04 ABCB9 ARPC1A C6orf106 CNOT6L CTNNB1 EML3 FKBP2 MST1 NEGR1 NEO1 PABPC4 PDXDC2 POM121C RBM6 RNF40 TMEM161B-AS1 ZDHHC5
Trunk fat-free mass 1.82 27 17 51.5 -0.23 2.6e-01 ABCB9 AC074117.10 ARHGEF40 B3GNT7 C2orf47 C6orf106 C7orf73 CEP120 CTNNB1 DNAJC18 ECE2 GPN3 HSD17B3 IGHMBP2 MED20 MYO9A NEGR1 NEK4 NRBP1 PABPC4 PRPF6 RBL2 RBM6 REEP2 RP11-156P1.3 TMEM110 ZBTB38
Hip circumference 1.89 24 21 63.6 -0.02 9.3e-01 ABCB9 ANKS3 C14orf159 C6orf106 CEP120 CTNNB1 DNAJC18 DRG2 ECE2 GPN3 MED20 NEGR1 PABPC4 PDXDC2 POM121C RBL2 RBM6 RNF40 RP11-95P2.1 SUN2 TMEM161B-AS1 TOM1L2 U91328.19 ZBTB38
Alcohol intake versus 10 years previously 1.63 6 2 6.1 0.79 6.0e-02 AC074117.10 MLIP MST1 NEGR1 PABPC4 RBM6
Worrier / anxious feelings 1.41 5 3 9.1 0.72 1.7e-01 GNL3 NEK4 PDXDC2 TMEM110 ZDHHC5
Frequency of tiredness / lethargy in last 2 weeks 1.50 6 2 6.1 -0.25 5.9e-01 AMT ECE2 GOLGA6A RP11-510D21.1 TRAIP ZDHHC5
Hair/balding pattern: Pattern 3 1.09 1 0 0.0 0.00 1.0e+00 RP3-511B24.6
Forced expiratory volume in 1-second (FEV1) 1.32 15 10 30.3 -0.47 6.4e-02 AMT BTBD1 C6orf106 CEP120 CTNNB1 DARS EML3 HSD17B3 MYO9A PCGF2 PDXDC2 PPP1R3E U91328.19 ZBTB38 ZDHHC5
Pulse rate 11.42 67 33 100.0 0.99 7.7e-72 AC007620.3 AC009948.5 AC074117.10 ACTN4 ALG10 AMT ARHGEF40 B3GNT7 BCAT1 C7orf73 CALCRL CEP120 CEP85L CPNE8 CTNNB1 DCP1A EML3 FADS1 FKBP7 FLRT2 FNIP2 FUT11 GIGYF1 GJA1 GNL3 HOMEZ IPO9 KIAA1755 LINC00961 LOC339524 MAPKAP1 MCM9 MEPCE MFF MKLN1-AS2 NAA16 NEK4 NEO1 OSBPL6 PPFIA2 PPP1R35 PPP1R3E PREP RBL2 RBM23 REEP2 RP11-171I2.5 RP11-318A15.2 RP11-381K20.5 RP11-510D21.1 RP11-66N24.4 SLC22A17 SPON1 SUN2 SVIL SYT10 TBC1D32 TCTEX1D1 TEKT3 TFR2 TKT TMEM110 TOM1L2 TRAIP VSNL1 VSTM2L ZBTB38
Qualifications: A levels/AS levels or equivalent 1.48 4 3 9.1 -0.32 6.0e-01 MST1 NEGR1 POM121C RBM6
Mouth/teeth dental problems: Dentures 1.14 1 0 0.0 0.00 1.0e+00 RBM6
Asthma 1.09 1 0 0.0 0.00 1.0e+00 FADS1
Medication: Cholesterol lowering 1.27 1 1 3.0 0.00 1.0e+00 AC074117.10
Forced expiratory volume in 1-second (FEV1), Best measure 1.35 11 7 21.2 -0.61 3.4e-02 BTBD1 C6orf106 CEP120 CTNNB1 DARS EML3 HSD17B3 MYO9A PCGF2 PDXDC2 ZBTB38
Impedance of arm (left) 1.66 24 17 51.5 0.37 6.1e-02 AC074117.10 AMT C2orf47 CEP120 DNAJC18 ECE2 EML3 FNIP2 GAB2 GNL3 GOLGA6A HNRNPD IGHMBP2 IPO9 NEGR1 NEK4 POM121C RBM6 REEP2 RP11-316O14.1 RP11-864G5.3 TMEM110 U91328.19 ZNF839
Arm fat mass (right) 1.79 25 17 51.5 0.30 1.4e-01 ABCB9 AC007620.3 ARPC1A C6orf106 CEP120 CNOT6L CTNNB1 DNAJC18 ECE2 FKBP2 GPN3 IPO9 MED20 MST1 NEGR1 NEO1 PABPC4 PDXDC2 POM121C RBM6 RNF40 RP11-95P2.1 TMEM161B-AS1 U91328.19 ZBTB38
Trunk predicted mass 1.82 26 17 51.5 -0.25 2.1e-01 ABCB9 AC074117.10 ARHGEF40 B3GNT7 C2orf47 C6orf106 C7orf73 CEP120 CTNNB1 DNAJC18 ECE2 GPN3 HSD17B3 IGHMBP2 MED20 MYO9A NEGR1 NEK4 NRBP1 PABPC4 PRPF6 RBL2 RBM6 REEP2 TMEM110 ZBTB38
Standing height 1.73 37 27 81.8 -0.28 9.4e-02 AC074117.10 AMT ANKS3 ARHGEF40 B3GNT7 BNIP1 C6orf106 C7orf73 CELF6 CEP120 CTNNB1 DNAJC18 FADS1 GLB1L GNL3 GOLGA6A GPBP1L1 HMGB1P31 HNRNPD HSD17B3 LA16c-OS12.2 LINC00266-1 MAPKAP1 MED20 MYO9A NRBP1 PDXDC2 PRPF6 PTPRJ RBL2 RP11-171I2.5 RP11-27I1.4 RP11-316O14.1 RP11-95P2.1 SLC25A28 SPON1 ZBTB38
Length of working week for main job 1.07 1 0 0.0 0.00 1.0e+00 FHOD3
Seen doctor (GP) for nerves, anxiety, tension or depression 1.61 2 2 6.1 0.00 1.0e+00 NEGR1 SGIP1
Hair/balding pattern: Pattern 4 1.07 6 4 12.1 -0.19 7.2e-01 ATP6V0D1 CTNNB1 FADS1 MKLN1-AS2 RP3-511B24.6 ZBTB38
Birth weight of first child 1.23 4 2 6.1 0.37 6.3e-01 POM121C RP11-864G5.3 SVIL ZBTB38
Peak expiratory flow (PEF) 1.10 1 0 0.0 0.00 1.0e+00 PCGF2
Pulse wave reflection index 2.49 5 1 3.0 -0.99 7.9e-04 HOMEZ KIAA1755 PPP1R3E TBC1D32 VSTM2L
Ever highly irritable/argumentative for 2 days 1.24 1 0 0.0 0.00 1.0e+00 RBM6
Medication: Paracetamol 1.37 2 0 0.0 0.00 1.0e+00 AMT MEF2D
Headache pain in last month 1.42 2 1 3.0 0.00 1.0e+00 MEF2D PABPC4
Medication for cholesterol, blood pressure or diabetes 1.32 2 1 3.0 0.00 1.0e+00 GATS PDXDC2
Gout (self-reported) 1.44 2 2 6.1 0.00 1.0e+00 AC074117.10 NRBP1
Hypothyroidism/myxoedema (self-reported) 1.18 3 1 3.0 -0.97 2.6e-02 FADS1 GIGYF1 MFSD6
Birth weight 1.09 2 1 3.0 0.00 1.0e+00 ARHGEF40 RP11-864G5.3
Forced vital capacity (FVC), Best measure 1.27 13 7 21.2 -0.43 1.2e-01 AMT ANKS3 BTBD1 C6orf106 CEP120 CTNNB1 DARS EML3 HSD17B3 MYO9A PDXDC2 RNASEH2C ZBTB38
Body fat percentage 1.62 24 12 36.4 0.57 2.7e-03 ABCB9 ARPC1A C6orf106 CNOT6L CTNNB1 DARS EML3 FKBP2 HNRNPD HSD17B3 MST1 NEGR1 NEO1 PABPC4 PDXDC2 POM121C RBM6 RNF40 RP11-95P2.1 RP3-511B24.6 TMEM161B-AS1 TRAIP U91328.19 ZBTB38
Leg fat percentage (right) 1.72 20 13 39.4 0.33 1.3e-01 ABCB9 ARPC1A C6orf106 CNOT6L DARS GPBP1L1 HNRNPD HSD17B3 MAPKAP1 MET MST1 NEGR1 NEO1 PDXDC2 POM121C RBM6 RNF40 RP11-95P2.1 RP3-511B24.6 U91328.19
Arm fat-free mass (right) 1.86 30 16 48.5 -0.18 3.3e-01 ABCB9 AC074117.10 ARHGEF40 B3GNT7 C2orf47 C6orf106 CEP120 CTNNB1 DNAJC18 ECE2 GPN3 HSD17B3 IGHMBP2 MED20 MET NEGR1 NRBP1 PABPC4 PAFAH2 POM121C PPP1R3E RBL2 RBM6 REEP2 RNASEH2C RP11-156P1.3 RP11-864G5.3 TMEM110 U91328.19 ZBTB38
Comparative body size at age 10 1.43 7 6 18.2 -0.27 5.6e-01 ATP6V0D1 CSPG5 HNRNPD IGHMBP2 NEGR1 RNF40 RP11-302B13.5
Worry too long after embarrassment 1.34 3 1 3.0 0.00 1.0e+00 RP11-510D21.1 TMEM161B-AS1 ZDHHC5
Wheeze or whistling in the chest in last year 1.37 2 1 3.0 0.00 1.0e+00 HSD17B3 RBM6
Age at first live birth 1.41 2 1 3.0 0.00 1.0e+00 NEO1 RBM6
Qualifications: College or University degree 1.67 12 4 12.1 -0.30 3.3e-01 AMT CSPG5 DCP1A FNIP2 LA16c-OS12.2 MST1 NEGR1 POM121C RBL2 RBM6 RP11-864G5.3 ZDHHC5
Medication for pain relief, constipation, heartburn 1.29 1 1 3.0 0.00 1.0e+00 MEF2D
Neck or shoulder pain in last month 1.15 1 0 0.0 0.00 1.0e+00 PABPC4
Migraine (self-reported) 1.19 2 1 3.0 0.00 1.0e+00 MEF2D SVIL
Medication: Allopurinol 1.26 2 2 6.1 0.00 1.0e+00 AC074117.10 NRBP1
Medication: Omeprazole 1.32 1 0 0.0 0.00 1.0e+00 C6orf106
Mean time to correctly identify matches 1.41 3 1 3.0 0.00 1.0e+00 KIAA1328 LA16c-OS12.2 RP11-302B13.5
Whole body fat mass 1.79 24 15 45.5 0.39 6.2e-02 ABCB9 ARPC1A C6orf106 CEP120 CNOT6L CTNNB1 DNAJC18 ECE2 FKBP2 GPN3 IPO9 MST1 NEGR1 NEO1 PABPC4 PDXDC2 POM121C RBM6 RNF40 RP11-95P2.1 RP3-511B24.6 TMEM161B-AS1 U91328.19 ZBTB38
Leg fat mass (right) 1.87 21 14 42.4 0.42 5.1e-02 ABCB9 ARPC1A C6orf106 CEP120 CNOT6L CTNNB1 GPN3 IPO9 MST1 NEGR1 NEO1 PABPC4 PDXDC2 POM121C RBM6 RNF40 RP11-95P2.1 RP3-511B24.6 TMEM161B-AS1 U91328.19 ZBTB38
Arm predicted mass (right) 1.88 26 16 48.5 -0.18 3.9e-01 ABCB9 AC074117.10 ARHGEF40 B3GNT7 C2orf47 C6orf106 CEP120 CTNNB1 DNAJC18 ECE2 GPN3 HSD17B3 IGHMBP2 MED20 NEGR1 NRBP1 PABPC4 PAFAH2 POM121C RBL2 RBM6 REEP2 RP11-864G5.3 TMEM110 U91328.19 ZBTB38
Alcohol intake frequency. 1.72 8 4 12.1 0.56 1.2e-01 AC074117.10 ECE2 MST1 NRBP1 PABPC4 RBM6 SUN2 ZDHHC5
Comparative height size at age 10 1.52 22 15 45.5 -0.33 1.4e-01 AC074117.10 ARHGEF40 B3GNT7 C6orf106 C7orf73 CEP120 CTNNB1 DNAJC18 ECE2 GPBP1L1 HMGB1P31 HNRNPD HSD17B3 LA16c-OS12.2 LINC00266-1 MYO9A PAFAH2 PRPF6 RBL2 RP11-171I2.5 RP11-27I1.4 ZBTB38
Overall health rating 1.73 7 3 9.1 0.42 2.9e-01 C6orf106 FNIP2 MST1 PABPC4 RBL2 RBM6 ZDHHC5
Age at last live birth 1.14 1 1 3.0 0.00 1.0e+00 RBM6
Leg pain on walking 1.34 1 1 3.0 0.00 1.0e+00 RBM6
Qualifications: NVQ or HND or HNC or equivalent 1.22 1 0 0.0 0.00 1.0e+00 RBM6
Medication: Aspirin 0.97 1 0 0.0 0.00 1.0e+00 MEF2D
Knee pain experienced in last month 1.13 2 0 0.0 0.00 1.0e+00 PABPC4 RBM6
Hypertension (Self-reported) 1.28 10 2 6.1 0.58 8.1e-02 ANKS3 CSPG5 GATS GOLGA6A MAPKAP1 NEGR1 PDXDC2 POM121C PTPRJ TMEM161B-AS1
Smoking status: Previous 1.43 1 0 0.0 0.00 1.0e+00 MSH6
Forced expiratory volume in 1-second (FEV1), predicted 1.34 3 2 6.1 0.00 1.0e+00 C6orf106 MYO9A ZBTB38
Whole body fat-free mass 1.87 28 17 51.5 -0.16 4.0e-01 ABCB9 AC074117.10 ARHGEF40 B3GNT7 C14orf159 C2orf47 C6orf106 C7orf73 CEP120 CTNNB1 DNAJC18 ECE2 GPN3 HSD17B3 IGHMBP2 MED20 NEGR1 NEK4 NRBP1 PABPC4 POM121C PRPF6 RBL2 RBM6 REEP2 TMEM110 U91328.19 ZBTB38
Leg fat-free mass (right) 1.86 24 20 60.6 -0.04 8.5e-01 ABCB9 AC074117.10 ARHGEF40 C14orf159 C2orf47 C6orf106 C7orf73 CEP120 CTNNB1 DNAJC18 ECE2 HSD17B3 IGHMBP2 MED20 NEGR1 PABPC4 POM121C RBL2 RBM6 RNF40 TMEM110 TMEM161B-AS1 VSTM2L ZBTB38
Arm fat percentage (left) 1.59 17 13 39.4 0.74 6.1e-04 ABCB9 ARPC1A C6orf106 CNOT6L CTNNB1 FKBP2 MST1 MYO9A NEGR1 NEO1 PABPC4 PDXDC2 POM121C RBM6 RNF40 TMEM161B-AS1 ZDHHC5
Average weekly red wine intake 1.28 2 1 3.0 0.00 1.0e+00 NEO1 ZDHHC5
Mood swings 1.05 1 0 0.0 0.00 1.0e+00 RBM6
Long-standing illness, disability or infirmity 1.30 2 0 0.0 0.00 1.0e+00 NEGR1 TMEM161B-AS1
Diabetes diagnosed by doctor 1.90 9 4 12.1 0.49 1.8e-01 AC074117.10 AMT NRBP1 PABPC4 PDXDC2 RBL2 RBM6 RP11-860B13.1 WFS1
Qualifications: nursing, teaching 1.40 3 1 3.0 0.00 1.0e+00 MST1 NEGR1 RBM6
Medication for cholesterol 1.15 1 0 0.0 0.00 1.0e+00 ANKS3
Back pain experienced in last month 1.15 1 0 0.0 0.00 1.0e+00 C6orf106
Asthma (self-reported) 1.11 2 0 0.0 0.00 1.0e+00 FADS1 GJA1
Osteoporosis (self-reported) 1.18 1 0 0.0 0.00 1.0e+00 CTNNB1
Medication: Aspirin 0.94 1 0 0.0 0.00 1.0e+00 MEF2D
Medication: Gliclazide 1.36 1 0 0.0 0.00 1.0e+00 WFS1
Smoking status: Current 1.22 2 1 3.0 0.00 1.0e+00 FNIP2 MAPKAP1
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.32 5 3 9.1 -0.43 3.9e-01 BTBD1 CEP120 EML3 GJA1 PCGF2
Whole body water mass 1.87 27 17 51.5 -0.16 4.4e-01 ABCB9 AC074117.10 ARHGEF40 B3GNT7 C14orf159 C2orf47 C6orf106 C7orf73 CEP120 CTNNB1 DNAJC18 ECE2 GPN3 HSD17B3 IGHMBP2 MED20 NEGR1 NEK4 NRBP1 PABPC4 POM121C PRPF6 RBL2 RBM6 REEP2 TMEM110 ZBTB38
Leg predicted mass (right) 1.87 24 18 54.5 -0.04 8.6e-01 ABCB9 AC074117.10 ARHGEF40 C14orf159 C2orf47 C6orf106 C7orf73 CEP120 CTNNB1 DNAJC18 ECE2 HSD17B3 IGHMBP2 MED20 NEGR1 PABPC4 POM121C RBL2 RBM6 RNF40 TMEM110 TMEM161B-AS1 VSTM2L ZBTB38
Arm fat mass (left) 1.80 24 16 48.5 0.36 8.9e-02 ABCB9 ARPC1A C6orf106 CEP120 CNOT6L CTNNB1 DNAJC18 ECE2 FKBP2 GPN3 IPO9 MED20 MST1 NEGR1 NEO1 PABPC4 PDXDC2 POM121C RBM6 RNF40 RP11-95P2.1 TMEM161B-AS1 U91328.19 ZBTB38
Number of self-reported non-cancer illnesses 1.18 2 1 3.0 0.00 1.0e+00 AC074117.10 NEGR1
Average weekly champagne plus white wine intake 1.34 1 0 0.0 0.00 1.0e+00 FADS1
Miserableness 1.31 2 1 3.0 0.00 1.0e+00 AMT RBM6
Guilty feelings 1.35 2 1 3.0 0.00 1.0e+00 ECE2 ZDHHC5
Mother's age at death 1.41 1 0 0.0 0.00 1.0e+00 MAPKAP1
Commuting to job workplace: Public transport 1.23 1 0 0.0 0.00 1.0e+00 NEGR1
Eye problems/disorders: Glaucoma 1.12 1 0 0.0 0.00 1.0e+00 PTPRJ
Medication: Blood pressure 1.17 1 0 0.0 0.00 1.0e+00 ANKS3
Supplements: Fish oil (including cod liver oil) 1.32 1 0 0.0 0.00 1.0e+00 TMEM216
High cholesterol (Self-reported) 1.28 2 2 6.1 0.00 1.0e+00 AC074117.10 NRBP1
Medication: Paracetamol 1.28 2 0 0.0 0.00 1.0e+00 AMT GOLGA6A
Medication: Atorvastatin 1.36 1 1 3.0 0.00 1.0e+00 AC074117.10
Ever smoked 1.46 4 2 6.1 0.08 9.2e-01 ARPC1A CSPG5 MSH6 VSNL1
Basal metabolic rate 1.90 28 18 54.5 -0.11 5.7e-01 ABCB9 AC074117.10 ARHGEF40 C14orf159 C2orf47 C6orf106 C7orf73 CEP120 CTNNB1 DNAJC18 ECE2 GPN3 HSD17B3 IGHMBP2 MED20 NEGR1 NRBP1 PABPC4 POM121C RBL2 RBM6 REEP2 RNF40 RP11-95P2.1 TMEM110 TMEM161B-AS1 U91328.19 ZBTB38
Leg fat percentage (left) 1.74 20 12 36.4 0.25 2.6e-01 ABCB9 ARPC1A C6orf106 CNOT6L DARS GPBP1L1 GPN3 HSD17B3 IPO9 MAPKAP1 MST1 NEGR1 NEO1 PDXDC2 POM121C RBM6 RNF40 RP11-95P2.1 RP3-511B24.6 U91328.19
Arm fat-free mass (left) 1.87 25 14 42.4 -0.16 4.5e-01 ABCB9 AC007620.3 AC074117.10 ARHGEF40 C14orf159 C2orf47 C6orf106 CEP120 CTNNB1 DNAJC18 ECE2 GPN3 HSD17B3 IGHMBP2 MED20 NEGR1 NRBP1 PABPC4 POM121C RBL2 RBM6 REEP2 RP11-864G5.3 U91328.19 ZBTB38
Average weekly beer plus cider intake 1.04 1 1 3.0 0.00 1.0e+00 RBM6
Irritability 1.32 1 0 0.0 0.00 1.0e+00 TMEM216
Ever had prostate specific antigen (PSA) test 1.26 1 0 0.0 0.00 1.0e+00 ZBTB38
Fractured/broken bones in last 5 years 1.26 1 0 0.0 0.00 1.0e+00 IGHMBP2
Diastolic blood pressure, automated reading 2.33 26 7 21.2 0.94 8.6e-14 ABCB9 AC007620.3 ANKS3 ARPC1A BTBD1 CEP120 CEP85L CSPG5 CSTA CTNNB1 DARS GATS GIGYF1 MAPKAP1 MST1 MYO9A PABPC4 POM121C RBM6 RNF40 SEC31B SPON1 TMEM161B-AS1 TMEM26 TRAIP WDR5B
Myopia 1.31 1 1 3.0 0.00 1.0e+00 EIF4E2
Vascular/heart problems diagnosed by doctor 1.24 7 0 0.0 -0.43 3.4e-01 ANKS3 GOLGA6A NEGR1 PDXDC2 POM121C PTPRJ TMEM161B-AS1
Cholesterol lowering medication 1.32 2 1 3.0 0.00 1.0e+00 AC074117.10 CALCRL
Pain experienced in last month 1.24 2 1 3.0 0.00 1.0e+00 PABPC4 RBM6
Impedance of whole body 1.62 24 21 63.6 0.25 2.2e-01 AC074117.10 AMT C14orf159 C2orf47 C6orf106 CEP120 DNAJC18 ECE2 EML3 GAB2 GNL3 GOLGA6A HNRNPD IGHMBP2 NEGR1 NEK4 PABPC4 PDXDC2 POM121C RBM6 REEP2 RP11-316O14.1 TMEM110 ZNF839
Leg fat mass (left) 1.88 23 14 42.4 0.40 5.3e-02 ABCB9 ARPC1A C6orf106 CEP120 CNOT6L CTNNB1 DNAJC18 FKBP2 GPN3 IPO9 MST1 NEGR1 NEO1 PABPC4 PDXDC2 POM121C RBM6 RNF40 RP11-95P2.1 RP3-511B24.6 TMEM161B-AS1 U91328.19 ZBTB38
Arm predicted mass (left) 1.86 24 15 45.5 -0.15 4.9e-01 ABCB9 AC074117.10 ARHGEF40 C2orf47 C6orf106 CEP120 CTNNB1 DNAJC18 ECE2 GPN3 HSD17B3 IGHMBP2 MED20 NEGR1 NRBP1 PABPC4 POM121C RBL2 RBM6 REEP2 RP11-156P1.3 RP11-864G5.3 U91328.19 ZBTB38

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 48 1.375 3.25
GTEx Adipose Visceral Omentum 36 1.768 3.37
GTEx Adrenal Gland 21 1.441 3.25
GTEx Artery Aorta 41 1.377 3.53
GTEx Artery Coronary 19 1.606 3.46
GTEx Artery Tibial 55 1.462 3.45
GTEx Brain Caudate basal ganglia 11 1.196 3.03
GTEx Brain Cerebellar Hemisphere 21 1.410 3.33
GTEx Brain Cerebellum 22 1.110 3.24
GTEx Brain Cortex 9 0.870 2.93
GTEx Brain Frontal Cortex BA9 10 1.082 2.96
GTEx Brain Hippocampus 2 0.382 2.64
GTEx Brain Hypothalamus 5 0.847 3.09
GTEx Brain Nucleus accumbens basal ganglia 12 1.387 3.16
GTEx Brain Putamen basal ganglia 9 1.442 4.02
GTEx Breast Mammary Tissue 31 1.570 3.32
GTEx Breast Mammary Tissue (Male) 10 0.838 2.98
GTEx Breast Mammary Tissue (Female) 25 1.521 3.31
GTEx Cells EBV-transformed lymphocytes 18 1.265 2.99
GTEx Cells Transformed fibroblasts 64 1.524 3.30
GTEx Colon Sigmoid 16 1.094 3.20
GTEx Colon Transverse 33 1.599 3.41
GTEx Esophagus Gastroesophageal Junction 26 1.799 3.54
GTEx Esophagus Mucosa 57 1.717 3.48
GTEx Esophagus Muscularis 44 1.361 3.39
GTEx Heart Atrial Appendage 33 2.090 4.62
GTEx Heart Left Ventricle 33 2.157 4.07
GTEx Liver 9 1.255 3.68
GTEx Lung 38 1.323 3.36
GTEx Muscle Skeletal 43 1.488 3.43
GTEx Nerve Tibial 79 1.828 3.67
GTEx Ovary 19 2.093 4.26
GTEx Pancreas 31 1.900 3.55
GTEx Pituitary 14 1.256 3.39
GTEx Prostate 12 1.437 3.52
GTEx Skin Not Sun Exposed Suprapubic 44 1.789 3.72
GTEx Skin Sun Exposed Lower leg 67 1.841 3.50
GTEx Small Intestine Terminal Ileum 5 1.085 2.96
GTEx Spleen 21 1.488 3.32
GTEx Stomach 25 1.719 3.47
GTEx Testis 44 1.395 3.33
GTEx Thyroid 60 1.500 3.41
GTEx Uterus 9 1.587 3.23
GTEx Vagina 14 2.205 3.47
GTEx Whole Blood 28 1.405 3.18
METSIM Adipose 53 1.150 3.04
NTR Blood 34 1.415 3.17
ROSMAP Brain Pre-frontal Cortex 61 1.389 3.27
YFS Blood 52 1.126 2.96
CommonMind Brain Pre-frontal Cortex 64 1.191 3.01
TCGA Breast Tumor 6 0.782 2.75
TCGA Breast Normal 45 1.070 2.74
TCGA Ovarian Tumor 24 0.821 2.60
TCGA Prostate Tumor 48 1.388 3.06