Hub : Traits :

Forced vital capacity (FVC), Best measure

2174 significantly associated models · 519 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 16142960 18461490 16 1 3.3e-32 3.2e-34 7.2e-04 92 MST1P2
2 1 25475418 27971502 10 2 3.7e-15 1.7e-13 4.9e-01 99 DHDDS TRIM63
3 1 36079508 37494602 2 1 6.6e-08 3.3e-07 1.0e+00 100 RP11-268J15.5
4 1 37628741 39167106 3 1 4.2e-08 7.1e-08 2.3e-02 82 RP11-109P14.10
5 1 40748755 42542658 4 1 1.5e-21 2.0e-21 1.0e-03 88 SCMH1
6 1 67814420 69212053 1 1 6.6e-08 1.2e-06 3.0e-01 96 DIRAS3
7 1 149672809 152070472 17 8 3.1e-17 3.9e-17 NaN NaN ANP32E CTSS HIST2H2AA3 PSMB4 RP11-196G18.24 RP11-316M1.12 SETDB1
8 1 153241677 154638826 1 1 2.1e-07 1.9e-06 4.9e-04 46 RP11-422P24.10
9 1 171640888 173105511 1 1 6.1e-08 2.3e-15 5.5e-12 24 PIGC
10 1 178129899 179534540 1 1 5.0e-09 1.0e-09 5.1e-02 90 ANGPTL1
11 1 180186713 181614143 1 1 1.5e-10 1.1e-10 1.0e+00 100 KIAA1614
12 1 182744205 184739300 2 2 1.9e-09 1.1e-08 2.1e-04 58 SMG7 TSEN15
13 1 203692179 205241659 2 1 4.5e-11 6.1e-11 1.0e-02 85 MDM4
14 1 217760821 220479607 2 2 9.6e-10 1.7e-16 4.7e-18 -10 RRP15 ZC3H11B
15 1 227222963 228614123 1 1 2.1e-10 7.5e-09 2.7e-03 73 JMJD4
16 2 23453834 25889403 8 3 9.8e-19 1.9e-17 5.6e-01 100 ADCY3 NCOA1 UBXN2A
17 2 35883253 37567226 5 1 1.3e-12 2.0e-11 5.6e-08 34 RP11-78I14.1
18 2 46117914 47538477 1 1 1.6e-07 3.4e-10 4.3e-04 68 PIGF
19 2 47845523 49300234 1 1 1.4e-07 1.3e-06 1.5e-01 91 FOXN2
20 2 54817683 56843605 2 2 8.3e-47 4.6e-60 1.0e-07 89 EFEMP1
21 2 67709195 69180661 1 1 3.0e-07 3.7e-06 5.1e-01 98 PPP3R1
22 2 69786188 72356449 4 2 3.9e-11 1.4e-08 1.0e+00 100 FAM136A ZNF638
23 2 100029106 101419887 1 1 2.4e-07 1.4e-07 7.3e-04 59 AC092667.2
24 2 135898023 137435625 2 1 8.8e-11 3.1e-08 1.3e-02 80 DARS
25 2 171683107 173114238 1 1 7.8e-10 3.1e-09 1.7e-03 72 CYBRD1
26 2 177559549 179178506 3 1 3.4e-13 5.6e-11 3.3e-01 98 AC073834.3
27 2 202434393 204433184 3 2 3.5e-08 1.7e-08 9.5e-01 100 BMPR2 ICA1L
28 2 216277672 217768442 1 1 2.2e-08 1.2e-08 1.0e+00 100 XRCC5
29 2 218300530 220226393 7 3 3.2e-12 1.5e-09 3.6e-06 41 CXCR2 PNKD
30 2 224544818 225959850 1 1 3.4e-08 4.2e-07 9.2e-06 23 FAM124B
31 2 231628878 233349588 4 2 3.0e-10 3.1e-11 7.3e-05 64 C2orf52 RP11-690I21.1
32 2 241133660 243048760 5 3 1.3e-23 9.9e-20 2.0e-07 67 BOK C2orf54 SEPT2
33 3 48702606 50448632 2 2 3.3e-08 6.0e-07 1.2e-02 74 GPX1 RNF123
34 3 52166147 53860103 3 1 3.3e-08 1.3e-06 4.8e-02 83 RFT1
35 3 56843028 58241059 1 1 2.5e-08 1.3e-07 5.5e-02 87 PDE12
36 3 128334272 129714372 1 1 2.0e-09 5.8e-11 5.4e-03 82 H1FX
37 3 137632815 139050702 1 1 2.3e-07 1.4e-07 1.1e-01 91 FAIM
38 3 140250247 142017527 3 4 2.7e-20 1.4e-20 1.0e+00 100 ACPL2 RASA2 ZBTB38
39 3 157125828 159106064 4 1 1.8e-18 6.1e-17 1.1e-01 96 RP11-538P18.2
40 3 171529470 172924003 1 1 4.2e-08 9.5e-14 1.2e-08 42 TNFSF10
41 3 196072442 197724684 1 2 1.2e-09 2.1e-10 9.5e-02 93 DLG1
42 4 644410 2058475 2 1 5.4e-09 8.7e-07 2.0e-01 93 CRIPAK
43 4 2811841 4219590 1 3 3.9e-11 1.3e-09 1.0e+00 100 LRPAP1
44 4 16922182 18533844 4 3 3.5e-47 1.8e-42 8.3e-02 98 DCAF16
45 4 57080198 58531645 2 1 4.4e-08 1.5e-08 8.7e-02 91 NOA1
46 4 105373669 107622327 5 2 3.0e-18 2.5e-21 7.5e-03 92 INTS12 PPA2
47 4 144758204 146788825 4 2 4.1e-26 6.2e-27 9.8e-03 94 ANAPC10 OTUD4
48 4 165595556 167114948 1 1 3.9e-07 2.8e-07 1.1e-01 90 CPE
49 5 77083651 78753539 1 1 8.4e-11 1.1e-20 2.2e-12 43 LHFPL2
50 5 107390303 109224099 1 1 2.3e-10 5.5e-13 6.6e-05 69 FER
51 5 114443019 115851911 1 1 2.1e-09 2.9e-08 6.2e-01 99 CDO1
52 5 121480516 123449266 3 2 1.3e-13 1.4e-13 7.1e-01 100 CEP120 CTB-36H16.2
53 5 126587995 128220643 3 1 9.5e-09 5.9e-08 1.9e-01 94 CTC-228N24.3
54 5 133240927 134784086 2 3 2.2e-10 1.4e-08 3.7e-04 61 CAMLG SAR1B
55 5 139323257 141294691 12 1 1.8e-09 1.1e-07 3.5e-01 97 PCDHB5
56 5 176040488 177260129 2 2 3.1e-14 1.3e-11 7.6e-04 75 MXD3 RAB24
57 6 25285943 26689223 1 2 1.1e-09 5.7e-11 9.8e-04 75 U91328.21
58 6 33686103 36804187 14 12 1.3e-20 2.6e-31 NaN NaN C6orf106 PACSIN1 RPL10A RPS10 TCP11 TEAD3 UHRF1BP1 ZNF76
59 6 75327919 76901651 1 1 1.8e-07 2.4e-06 9.6e-01 100 FILIP1
60 6 80120201 81763771 2 1 3.7e-12 3.1e-12 1.0e+00 100 RP11-250B2.6
61 6 108994161 110844259 7 1 1.4e-11 1.1e-11 1.0e+00 100 RP11-425D10.10
62 6 115569351 117481404 4 1 4.3e-10 1.6e-09 1.8e-01 95 RP1-93H18.7
63 6 125970401 127355237 1 1 4.8e-32 1.9e-34 6.4e-04 92 CENPW
64 6 129638583 132080991 3 2 4.2e-24 7.1e-26 7.1e-14 49 EPB41L2 L3MBTL3
65 6 134905567 136516257 1 1 2.5e-09 5.0e-08 2.3e-01 95 AHI1
66 6 141924760 143855272 2 1 1.6e-23 2.0e-25 1.0e+00 100 GPR126
67 6 151743948 153655470 1 1 1.0e-09 9.1e-12 5.3e-07 46 SYNE1
68 6 158041511 159632250 1 1 3.5e-09 6.8e-10 1.0e+00 100 TULP4
69 7 2032803 3581391 2 1 7.0e-12 1.4e-11 1.0e+00 100 GNA12
70 7 22946782 24382726 1 1 3.1e-09 4.0e-18 7.2e-11 44 CCDC126
71 7 91539717 93160671 1 1 1.2e-11 3.2e-11 1.6e-02 87 CDK6
72 7 99792666 101185166 1 1 5.3e-09 5.9e-07 6.2e-03 70 ACHE
73 7 139700516 141316834 2 1 3.4e-10 4.0e-10 1.0e+00 100 BRAF
74 7 149847287 151252618 1 1 1.5e-08 5.3e-10 7.4e-04 70 AOC1
75 8 56269387 57683880 2 1 1.3e-14 9.6e-24 8.8e-11 58 RPS20
76 8 119737284 121136001 1 1 1.6e-09 7.5e-11 1.1e-09 12 NOV
77 8 123101743 124679448 1 1 2.8e-09 1.3e-09 3.4e-02 88 ZHX2
78 8 130062993 131498180 1 1 8.5e-18 3.3e-20 2.2e-07 68 GSDMC
79 8 135106207 136500554 1 1 8.9e-09 1.4e-13 6.4e-11 22 AC083843.1
80 9 14857740 16758776 1 1 1.6e-10 7.7e-11 9.2e-02 93 CCDC171
81 9 96326127 100114913 12 9 2.2e-18 5.8e-23 5.9e-02 96 C9orf102 C9orf3 CDC14B ERCC6L2 PTCH1 RP11-435O5.4 RP11-435O5.5 ZNF169
82 9 135629944 137034272 1 1 2.1e-08 4.6e-11 1.7e-04 67 CACFD1
83 9 138403706 139836362 1 1 2.3e-23 8.5e-22 7.9e-02 97 QSOX2
84 10 11515875 12989666 2 1 5.2e-09 7.2e-10 1.3e-02 84 NUDT5
85 10 21087485 22724472 2 1 4.0e-08 2.2e-08 1.3e-01 93 CASC10
86 10 30435876 32016090 1 1 2.4e-07 1.1e-08 1.0e+00 100 ZNF438
87 10 60712592 62185494 1 1 7.2e-08 1.2e-08 1.3e-08 1 SLC16A9
88 10 63870456 65264300 1 1 1.8e-08 2.3e-07 1.6e-02 78 ADO
89 10 76664253 80383574 3 2 2.3e-08 1.2e-10 2.5e-04 68 C10orf11 DLG5
90 10 80443273 82136664 2 2 2.6e-11 1.1e-07 8.6e-02 90 ZCCHC24
91 10 103527782 104934709 1 1 4.2e-08 1.3e-05 8.6e-02 84 TMEM180
92 10 123438113 124889817 1 1 1.3e-08 1.2e-18 8.4e-14 28 PLEKHA1
93 11 46010847 48783497 22 1 3.9e-15 3.5e-13 3.3e-01 98 C1QTNF4
94 11 61627881 63078986 4 1 2.6e-09 7.5e-09 1.0e+00 100 ROM1
95 11 64663227 69476279 15 8 6.2e-37 4.4e-34 1.0e+00 100 CATSPER1 CCS DPP3 MRGPRF RAD9A SF3B2
96 11 88358544 89851689 1 1 2.2e-08 1.9e-09 2.6e-03 75 NOX4
97 12 27616589 29042392 1 1 1.9e-14 2.5e-12 6.6e-01 100 RP11-967K21.1
98 12 30084002 31526510 1 1 2.4e-08 9.3e-09 1.0e+00 100 IPO8
99 12 55633142 57684978 12 6 5.5e-12 1.9e-10 1.0e+00 100 CNPY2 IL23A RBMS2 RP11-977G19.11
100 12 64519806 66337026 2 1 3.9e-11 1.8e-17 4.0e-12 34 LEMD3
101 12 93165619 94589220 1 1 9.9e-12 3.0e-24 3.2e-15 40 MRPL42
102 12 101575652 103148974 2 2 9.5e-10 7.3e-10 1.2e-02 83 CCDC53 DRAM1
103 13 49557805 51390447 3 2 6.1e-18 6.6e-17 1.0e+00 100 DLEU2 EBPL
104 13 114302502 115106996 1 1 2.5e-07 4.8e-07 1.2e-01 90 CDC16
105 14 92286262 93847625 1 1 2.4e-13 4.2e-14 1.0e+00 100 RIN3
106 15 39530508 41012695 1 1 6.9e-09 1.9e-07 1.5e-05 31 EIF2AK4
107 15 50649361 52091785 1 1 2.1e-07 5.6e-10 5.9e-04 69 TNFAIP8L3
108 15 66797492 68245488 1 1 2.3e-07 2.1e-09 6.5e-04 68 AAGAB
109 15 71418503 73087366 1 1 1.3e-10 4.2e-10 1.6e-05 52 MYO9A
110 15 73524629 78022087 10 5 3.3e-18 8.1e-27 1.5e-16 41 CLK3 LOXL1-AS1 MAN2C1 PSTPIP1
111 15 78135979 79537269 1 1 4.7e-08 5.4e-09 4.0e-02 88 PSMA4
112 15 83167559 85883064 10 7 7.9e-13 1.2e-20 4.4e-01 99 AC103965.1 GOLGA6L5 RP11-382A20.2 WHAMM
113 15 99816860 101209341 1 1 1.4e-10 2.6e-13 1.6e-10 24 CTD-3076O17.1
114 16 86671 1488646 1 1 2.3e-07 6.2e-08 1.0e-09 -27 NARFL
115 16 2741812 5510848 9 2 6.5e-16 6.8e-16 3.4e-04 80 CLUAP1 ZNF500
116 16 8016708 9438692 1 1 2.6e-08 8.3e-09 1.5e-04 57 METTL22
117 16 13697975 15369019 2 1 2.1e-09 5.6e-08 2.0e-05 38 NPIPA2
118 16 29580611 31892919 15 8 4.0e-14 1.5e-12 1.0e+00 100 BCKDK FUS HSD3B7 KAT8 MIR4519 RP11-196G11.2 SETD1A STX4
119 16 68523336 71093625 15 3 9.1e-17 1.8e-25 1.3e-01 98 NFAT5 NOB1 TMED6
120 16 80779331 82901701 2 6 2.0e-08 5.6e-08 1.0e+00 100 CMIP MPHOSPH6
121 16 88030355 90172696 2 2 1.1e-07 1.3e-06 4.6e-03 66 CHMP1A SNAI3-AS1
122 17 923916 2420934 3 1 2.1e-09 2.7e-08 8.1e-01 100 SERPINF1
123 17 6644945 8041014 1 1 3.2e-07 3.2e-07 1.0e+00 100 RP11-104H15.8
124 17 27200734 29126951 6 1 8.6e-09 5.8e-08 3.4e-01 97 ANKRD13B
125 17 36211659 37644854 2 1 1.0e-08 3.4e-07 1.8e-01 93 PIP4K2B
126 17 41946180 47389935 36 8 2.4e-39 5.9e-31 1.0e+00 100 ADAM11 ARL17B HOXB4 KANSL1 LRRC37A LRRC37A2 PLCD3
127 17 60821100 64251733 23 10 1.2e-29 2.5e-25 1.0e+00 100 AXIN2 CCDC47 CD79B CYB561 ICAM2 PECAM1 PLEKHM1P SMARCD2 STRADA
128 17 78665405 80866427 7 3 4.3e-16 2.1e-14 4.5e-01 99 ASPSCR1 DCXR RP11-1055B8.4
129 18 69836 907710 1 1 1.3e-07 5.8e-06 7.0e-05 23 USP14
130 18 21613385 23204100 1 1 5.3e-09 9.4e-11 1.3e-06 44 RP11-449D8.5
131 18 59159599 60668346 1 1 1.4e-08 1.8e-04 2.0e-04 2 KIAA1468
132 19 288246 1691725 1 1 3.9e-07 7.6e-08 7.1e-02 89 WDR18
133 19 3309021 4732167 1 1 1.0e-07 9.0e-09 3.3e-03 74 PIAS4
134 19 10016470 11459260 2 1 1.3e-09 2.2e-10 8.5e-03 83 ILF3-AS1
135 19 40403029 43637183 4 2 2.2e-13 2.3e-13 1.0e+00 100 CXCL17 SHKBP1
136 19 45585167 46981943 1 1 1.5e-07 9.1e-09 1.8e-03 70 DMPK
137 20 9925555 11347455 1 1 3.9e-09 1.9e-08 9.7e-03 79 JAG1
138 20 20407782 21919054 1 1 3.9e-07 5.9e-08 1.0e+00 100 PLK1S1
139 20 31382860 35226873 11 3 3.2e-11 1.2e-12 1.3e-04 71 E2F1 PHF20 TP53INP2
140 20 43723627 45205482 3 1 3.0e-11 2.9e-08 6.5e-02 89 ZSWIM1
141 20 46551079 48603940 7 1 1.9e-19 1.0e-22 1.0e+00 100 ARFGEF2
142 20 61561153 62912463 6 1 7.6e-13 1.8e-12 1.2e-03 79 ZGPAT
143 22 29966083 31360592 1 1 3.5e-07 3.4e-10 9.6e-06 50 OSM
144 22 42563308 44107669 1 1 9.3e-08 1.1e-05 8.1e-01 100 PACSIN2

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Alzheimer’s Disease (including proxy) 1.70 5 2 6.1 -0.97 6.2e-03 BCKDK HSD3B7 KAT8 SETD1A STX4
Crohns Disease (2017) 1.35 8 5 15.2 0.22 5.9e-01 ADCY3 ADO GPX1 RFT1 RP11-268J15.5 ZBTB38 ZGPAT ZSWIM1
Irritable Bowel Disease (IBD) 1.47 10 4 12.1 -0.39 2.6e-01 ADCY3 ADO CTSS CXCR2 GNA12 GPX1 NCOA1 RP11-316M1.12 SETDB1 ZGPAT
Ulcerative Colitis (UC) 1.43 3 2 6.1 0.00 1.0e+00 GNA12 GPX1 RNF123
Reaction Time 1.47 5 3 9.1 0.82 8.9e-02 KANSL1 LRRC37A2 PIAS4 TMEM180 ZNF638
Verbal and Numeric Reasoning (VNR) 1.69 13 7 21.2 -0.82 3.8e-04 ARFGEF2 ARL17B C1QTNF4 CDC14B CENPW DCAF16 GPX1 LRRC37A PPA2 RNF123 U91328.21 UBXN2A ZNF638
Breast Cancer 1.72 11 9 27.3 0.25 4.2e-01 ADCY3 CASC10 HIST2H2AA3 L3MBTL3 LRRC37A LRRC37A2 RIN3 RP11-196G18.24 SYNE1 ZBTB38 ZSWIM1
Ovarian Cancer 1.32 4 2 6.1 -0.99 1.1e-02 CASC10 HOXB4 LRRC37A LRRC37A2
Prostate Cancer 1.63 3 1 3.0 0.00 1.0e+00 GPX1 MDM4 TMEM180
Age at First Birth 1.12 1 1 3.0 0.00 1.0e+00 GPX1
Body Mass Index (BMI) (2010) 1.31 2 0 0.0 0.00 1.0e+00 ADCY3 C1QTNF4
Coronary Artery Disease (CAD) 1.53 1 1 3.0 0.00 1.0e+00 ICA1L
Crohns Disease (2012) 1.31 2 1 3.0 0.00 1.0e+00 ADO ZGPAT
HDL Cholesterol 1.19 3 1 3.0 0.00 1.0e+00 C1QTNF4 UHRF1BP1 ZSWIM1
LDL Cholesterol 1.19 2 1 3.0 0.00 1.0e+00 CACFD1 ICA1L
Lupus 1.34 4 1 3.0 0.97 3.2e-02 C6orf106 TCP11 UHRF1BP1 ZNF76
Neuroticism 1.47 3 1 3.0 0.00 1.0e+00 GPX1 LRRC37A LRRC37A2
Primary Biliary Cirrhosis 1.21 1 0 0.0 0.00 1.0e+00 LRRC37A
Rheumatoid Arthritis 1.16 1 0 0.0 0.00 1.0e+00 CDK6
Schizophrenia 1.17 3 1 3.0 -0.10 8.5e-01 AC103965.1 CTSS FOXN2
Triglycerides 1.10 2 0 0.0 0.00 1.0e+00 KAT8 SETD1A
Ulcerative Colitis 1.41 2 2 6.1 0.00 1.0e+00 GNA12 GPX1
Blood Eosinophil Count 1.24 42 28 84.8 0.06 6.8e-01 AAGAB AC103965.1 ADO AHI1 ARL17B CACFD1 CATSPER1 CDK6 CTC-228N24.3 CTSS CXCL17 DLEU2 FAM136A GNA12 GPX1 ICA1L KANSL1 KAT8 KIAA1614 L3MBTL3 LRRC37A LRRC37A2 MRGPRF NARFL NOA1 NOB1 PACSIN1 PSTPIP1 RFT1 RIN3 RP11-316M1.12 RP11-425D10.10 RPS10 SEPT2 SETD1A SETDB1 SF3B2 TCP11 TEAD3 TRIM63 ZNF169 ZNF76
Blood Platelet Count 1.37 50 39 118.2 0.50 1.0e-04 AC103965.1 ADAM11 ADO ANKRD13B C1QTNF4 CACFD1 CDC14B CDK6 CEP120 CTSS CXCR2 DCAF16 DMPK E2F1 FAIM FAM124B FAM136A FER GNA12 ICA1L KIAA1614 LRRC37A MAN2C1 MIR4519 NARFL NOA1 OSM OTUD4 PACSIN1 PACSIN2 PDE12 PECAM1 PNKD RBMS2 RIN3 RP11-316M1.12 RP11-425D10.10 RPL10A RPS10 SCMH1 SETDB1 SMARCD2 TMEM180 TRIM63 UHRF1BP1 XRCC5 ZCCHC24 ZGPAT ZHX2 ZNF500
Blood Red Count 1.94 55 40 121.2 0.05 7.4e-01 AC103965.1 ANKRD13B AOC1 ARL17B ASPSCR1 BCKDK BMPR2 CACFD1 CCS CD79B CENPW CHMP1A CNPY2 CXCR2 DARS E2F1 EIF2AK4 FAM136A FUS GPR126 HOXB4 HSD3B7 IL23A KANSL1 KAT8 L3MBTL3 LRRC37A LRRC37A2 MAN2C1 MIR4519 MST1P2 MYO9A NFAT5 NOB1 NOV PHF20 PIAS4 PSMB4 PSTPIP1 RAB24 RAD9A RASA2 RP11-196G11.2 RP11-435O5.5 RP11-977G19.11 SEPT2 SETD1A SHKBP1 SNAI3-AS1 STRADA STX4 ZBTB38 ZGPAT ZNF500 ZSWIM1
Blood White Count 1.54 52 33 100.0 0.52 3.0e-05 ADO AHI1 ANKRD13B BMPR2 C1QTNF4 CACFD1 CCDC126 CCDC47 CDC14B CDK6 CENPW CEP120 CTB-36H16.2 CXCL17 CXCR2 DCAF16 DLG5 EBPL FER FUS GNA12 GPX1 HOXB4 KIAA1614 L3MBTL3 LRRC37A MAN2C1 NOA1 NOB1 PACSIN1 PCDHB5 PNKD PSTPIP1 PTCH1 RFT1 RIN3 RP11-1055B8.4 RP11-435O5.5 RPL10A SCMH1 SETD1A SLC16A9 SMARCD2 TMEM180 TULP4 UBXN2A ZGPAT ZHX2 ZNF169 ZNF500 ZNF638 ZNF76
Heel T-Score 2.70 77 61 184.8 0.15 1.7e-01 AAGAB AC103965.1 ADCY3 ANAPC10 ANKRD13B ANP32E ARL17B ASPSCR1 AXIN2 CACFD1 CCDC53 CDK6 CEP120 CHMP1A CRIPAK CTB-36H16.2 CTSS CXCR2 CYBRD1 DCAF16 DIRAS3 DLEU2 DLG1 E2F1 EBPL EPB41L2 FAIM FUS GNA12 GPR126 GSDMC HIST2H2AA3 HSD3B7 IPO8 JAG1 JMJD4 KANSL1 KAT8 KIAA1614 L3MBTL3 LRRC37A LRRC37A2 MRGPRF NOA1 NOV OSM PDE12 PIGC PIP4K2B PLCD3 PLEKHM1P RASA2 RFT1 ROM1 RP11-104H15.8 RP11-109P14.10 RP11-196G18.24 RP11-435O5.4 RP11-435O5.5 RP11-967K21.1 RPL10A RPS20 RRP15 SCMH1 SETD1A SLC16A9 SMARCD2 SNAI3-AS1 SYNE1 TNFAIP8L3 TULP4 WHAMM ZBTB38 ZCCHC24 ZNF169 ZNF638 ZNF76
BMI 2.06 53 31 93.9 0.70 3.5e-09 AAGAB AC092667.2 ACHE ADCY3 ANKRD13B ARFGEF2 BCKDK C1QTNF4 C6orf106 CASC10 CCDC171 CCDC47 CCS CDC14B CEP120 CMIP CXCL17 CXCR2 DCAF16 DLG1 EIF2AK4 FUS GPR126 GPX1 HOXB4 HSD3B7 KAT8 L3MBTL3 LOXL1-AS1 MST1P2 MYO9A NCOA1 NFAT5 NOB1 OTUD4 PACSIN1 PIAS4 PIGF PSMB4 PSTPIP1 RFT1 RNF123 RP11-449D8.5 RP11-538P18.2 RPS10 SAR1B SETD1A SLC16A9 SMARCD2 STX4 TMED6 UHRF1BP1 ZCCHC24
Height 10.44 193 185 560.6 -0.91 5.0e-84 AAGAB AC083843.1 AC103965.1 ACHE ACPL2 ADAM11 ADCY3 ADO AHI1 ANAPC10 ANKRD13B ANP32E AOC1 ARFGEF2 ARL17B ASPSCR1 AXIN2 BMPR2 BOK BRAF C10orf11 C1QTNF4 C2orf52 C2orf54 C6orf106 C9orf102 C9orf3 CACFD1 CAMLG CATSPER1 CCDC126 CCDC47 CCDC53 CCS CD79B CDC14B CDC16 CDK6 CDO1 CENPW CEP120 CHMP1A CLK3 CLUAP1 CMIP CNPY2 CPE CRIPAK CTC-228N24.3 CTD-3076O17.1 CTSS CXCL17 CXCR2 CYB561 CYBRD1 DCAF16 DHDDS DIRAS3 DLEU2 DLG5 DPP3 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 EPB41L2 ERCC6L2 FAIM FAM124B FAM136A FER FILIP1 GNA12 GOLGA6L5 GPR126 GPX1 GSDMC H1FX HIST2H2AA3 HOXB4 ICA1L ICAM2 IL23A ILF3-AS1 IPO8 JAG1 JMJD4 KANSL1 KIAA1614 L3MBTL3 LEMD3 LHFPL2 LOXL1-AS1 LRRC37A LRRC37A2 MAN2C1 MDM4 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1P2 MXD3 MYO9A NARFL NCOA1 NFAT5 NOA1 NOB1 NOV NOX4 NPIPA2 OTUD4 PACSIN1 PACSIN2 PCDHB5 PECAM1 PHF20 PIAS4 PIGC PIGF PIP4K2B PLCD3 PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PPP3R1 PSMB4 PSTPIP1 PTCH1 QSOX2 RAB24 RAD9A RASA2 RBMS2 RFT1 RP11-104H15.8 RP11-1055B8.4 RP11-109P14.10 RP11-196G18.24 RP11-250B2.6 RP11-268J15.5 RP11-382A20.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-538P18.2 RP11-690I21.1 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RP1-93H18.7 RPL10A RPS10 RPS20 RRP15 SAR1B SCMH1 SEPT2 SERPINF1 SETDB1 SF3B2 SHKBP1 SLC16A9 SMARCD2 SNAI3-AS1 STRADA SYNE1 TCP11 TEAD3 TMED6 TMEM180 TNFAIP8L3 TNFSF10 TP53INP2 TRIM63 TSEN15 TULP4 UBXN2A USP14 ZBTB38 ZC3H11B ZCCHC24 ZHX2 ZNF169 ZNF438 ZNF500 ZNF638 ZNF76 ZSWIM1
Waist Hip Ratio (WHR) 1.84 37 20 60.6 0.31 5.2e-02 AAGAB AC103965.1 ADCY3 ANAPC10 ASPSCR1 BCKDK CCDC53 CD79B CENPW CLUAP1 CTC-228N24.3 DLEU2 EBPL FAIM GOLGA6L5 GPX1 H1FX L3MBTL3 LRRC37A LRRC37A2 NFAT5 OSM OTUD4 PHF20 PIP4K2B PLK1S1 RAB24 RAD9A ROM1 RPS10 SF3B2 STRADA TNFAIP8L3 UHRF1BP1 ZBTB38 ZCCHC24 ZNF438
Systolic Blood Pressure 1.66 35 22 66.7 0.48 1.8e-03 ACPL2 ADAM11 ADCY3 ADO ARFGEF2 CDC16 CDK6 CTC-228N24.3 CYBRD1 DCAF16 EFEMP1 EPB41L2 FER GPX1 HOXB4 ICA1L JMJD4 KANSL1 LRRC37A LRRC37A2 NOV NUDT5 PCDHB5 PPP3R1 RIN3 RP11-1055B8.4 RP11-109P14.10 RP11-538P18.2 RPL10A RPS10 TCP11 ZGPAT ZHX2 ZNF500 ZNF76
Smoking Status 1.31 8 2 6.1 -0.01 9.9e-01 BCKDK CASC10 GPX1 KANSL1 LRRC37A2 NOB1 RFT1 TMEM180
Allergy or Eczema 1.46 9 6 18.2 0.03 9.4e-01 AAGAB AHI1 CXCR2 GNA12 PACSIN1 RASA2 TMEM180 ZBTB38 ZGPAT
Cardiovascular Disease 1.75 20 10 30.3 0.83 4.2e-06 AAGAB BCKDK CDC16 CDK6 CHMP1A DCAF16 FAIM FOXN2 FUS HSD3B7 KAT8 MXD3 PPP3R1 RP11-1055B8.4 RP11-538P18.2 SETD1A SMARCD2 STX4 ZGPAT ZSWIM1
Hypothyroidism (self reported) 1.25 6 4 12.1 0.29 5.7e-01 AHI1 PLEKHA1 RIN3 RP11-109P14.10 SEPT2 UHRF1BP1
Respiratory disease 1.73 8 4 12.1 0.76 1.0e-02 AAGAB AHI1 ICA1L NOA1 TCP11 ZGPAT ZNF169 ZNF76
Type 2 Diabetes (T2D) 1.57 7 3 9.1 0.58 1.8e-01 CENPW DMPK HOXB4 MAN2C1 NOB1 NUDT5 ZCCHC24
Lung FEV1/FVC ratio 4.03 49 38 115.2 0.26 5.1e-02 AC103965.1 ACHE ADCY3 ADO ANKRD13B C10orf11 CASC10 CCDC171 CENPW CTC-228N24.3 DRAM1 EFEMP1 EIF2AK4 GNA12 GPR126 HIST2H2AA3 ICA1L INTS12 LOXL1-AS1 LRRC37A MST1P2 NCOA1 NOA1 NOV NUDT5 OTUD4 PDE12 PIP4K2B PLEKHA1 PLEKHM1P PPA2 PSMA4 PSTPIP1 PTCH1 RASA2 ROM1 RP11-268J15.5 RP11-382A20.2 RP11-435O5.5 RPL10A RPS20 RRP15 SEPT2 SETD1A SHKBP1 TCP11 WHAMM ZBTB38 ZNF76
Lung FVC 6.02 129 98 297.0 -0.90 1.3e-52 AAGAB AC073834.3 AC092667.2 ADAM11 AHI1 ANAPC10 ANGPTL1 AOC1 ARFGEF2 ARL17B ASPSCR1 BCKDK BMPR2 BOK BRAF C10orf11 C2orf54 C9orf3 CACFD1 CASC10 CATSPER1 CCDC126 CCDC171 CD79B CENPW CEP120 CLUAP1 CPE CTB-36H16.2 CTC-228N24.3 CTSS CXCR2 DARS DCAF16 DCXR DHDDS DIRAS3 DLG1 DPP3 EBPL EFEMP1 EIF2AK4 FAIM FAM136A FOXN2 FUS GPX1 HOXB4 HSD3B7 ICA1L INTS12 IPO8 JAG1 KANSL1 KAT8 KIAA1614 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 MAN2C1 MDM4 METTL22 MIR4519 MST1P2 NFAT5 NOA1 NOB1 NOV NOX4 NPIPA2 NUDT5 OSM PACSIN2 PCDHB5 PDE12 PECAM1 PHF20 PLCD3 PLEKHM1P PLK1S1 PPA2 PSMA4 PTCH1 QSOX2 RAD9A RIN3 RNF123 ROM1 RP11-1055B8.4 RP11-196G11.2 RP11-250B2.6 RP11-316M1.12 RP11-382A20.2 RP11-422P24.10 RP11-425D10.10 RP11-435O5.5 RP11-449D8.5 RP11-538P18.2 RP11-78I14.1 RP11-967K21.1 RPL10A RPS20 RRP15 SAR1B SCMH1 SETD1A SETDB1 SF3B2 SHKBP1 SMG7 SNAI3-AS1 STRADA STX4 TCP11 TEAD3 TRIM63 TULP4 UBXN2A USP14 WDR18 WHAMM XRCC5 ZBTB38 ZC3H11B ZCCHC24 ZGPAT ZNF438 ZNF76
Neuroticism 1.91 14 11 33.3 0.26 3.5e-01 AAGAB ARL17B CENPW FUS GPX1 HSD3B7 KANSL1 LRRC37A LRRC37A2 MIR4519 PTCH1 RP11-196G11.2 SETD1A STX4
Chronotype (morning person) 1.18 5 1 3.0 0.68 2.0e-01 CRIPAK CTSS CXCL17 CYB561 SETDB1
Hair Pigment 0.73 24 20 60.6 0.05 7.9e-01 ACPL2 ADO ANP32E ASPSCR1 BRAF CHMP1A DCXR DPP3 E2F1 FAM136A HIST2H2AA3 L3MBTL3 LRRC37A MRGPRF NOA1 NOX4 PHF20 RASA2 RP11-268J15.5 SNAI3-AS1 TP53INP2 ZBTB38 ZCCHC24 ZNF76
Tanning 0.78 12 12 36.4 -0.68 1.4e-02 ADCY3 ADO CHMP1A CTSS E2F1 MXD3 NOX4 PHF20 RP11-316M1.12 SETDB1 SNAI3-AS1 TP53INP2
Hand grip strength (left) 4.19 45 26 78.8 0.95 1.4e-25 ADAM11 ADCY3 AOC1 ARFGEF2 AXIN2 BRAF C1QTNF4 CCDC53 CCS CD79B CHMP1A CRIPAK CYB561 DARS DCAF16 DLG5 FER HOXB4 JAG1 JMJD4 KANSL1 L3MBTL3 LOXL1-AS1 LRRC37A LRRC37A2 NCOA1 NOB1 PHF20 PIGF PIP4K2B PLCD3 PPP3R1 RAD9A RASA2 RFT1 RP11-250B2.6 SETD1A SETDB1 STRADA TCP11 TMEM180 ZBTB38 ZCCHC24 ZNF500 ZNF76
Number of treatments/medications taken 1.59 6 0 0.0 -0.92 3.2e-03 CASC10 CCS DCAF16 FAIM GPX1 PIAS4
Sensitivity / hurt feelings 1.74 5 5 15.2 -0.68 1.4e-01 ARL17B KANSL1 LRRC37A LRRC37A2 PTCH1
Frequency of depressed mood in last 2 weeks 1.13 1 0 0.0 0.00 1.0e+00 RP11-268J15.5
Relative age of first facial hair 1.73 6 4 12.1 -0.43 3.3e-01 KANSL1 LEMD3 LRRC37A LRRC37A2 NPIPA2 ZBTB38
Ever had hysterectomy (womb removed) 1.22 1 0 0.0 0.00 1.0e+00 CASC10
Systolic blood pressure, automated reading 1.81 22 8 24.2 -0.57 3.3e-03 ADCY3 ADO CDC16 CDK6 DCAF16 EFEMP1 FER GPX1 HOXB4 LRRC37A LRRC37A2 NOV NUDT5 PPA2 PPP3R1 RP11-1055B8.4 RP11-538P18.2 TCP11 U91328.21 ZGPAT ZHX2 ZNF500
Medication: Metformin 1.46 2 0 0.0 0.00 1.0e+00 NUDT5 ZCCHC24
Diabetes (mother) 1.44 1 1 3.0 0.00 1.0e+00 NUDT5
Pack years adult smoking proportion 2.22 4 1 3.0 -0.86 1.4e-01 CYB561 GPX1 PIAS4 PSMA4
Impedance of leg (right) 2.53 41 26 78.8 -0.02 9.0e-01 AC103965.1 ADAM11 ADCY3 ANP32E AOC1 BCKDK CCS CD79B CDK6 CDO1 CEP120 CTC-228N24.3 CTD-3076O17.1 CTSS CYBRD1 FER GPX1 HIST2H2AA3 KAT8 L3MBTL3 LOXL1-AS1 LRRC37A MRGPRF MST1P2 OTUD4 PACSIN1 PHF20 PLK1S1 PSTPIP1 PTCH1 RAD9A RFT1 RIN3 RP11-268J15.5 RP11-382A20.2 RP11-425D10.10 RPS10 RPS20 SNAI3-AS1 STRADA UHRF1BP1
Leg fat-free mass (left) 5.16 100 74 224.2 0.88 5.1e-37 AC083843.1 ACPL2 ADAM11 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDK BOK C2orf52 CCDC126 CCDC53 CD79B CDC14B CDC16 CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CYBRD1 DCAF16 DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 EPB41L2 FAM124B FUS GNA12 GPR126 GSDMC H1FX HIST2H2AA3 ILF3-AS1 IPO8 JMJD4 KANSL1 KAT8 KIAA1614 L3MBTL3 LHFPL2 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MXD3 NARFL NCOA1 NOV NPIPA2 OTUD4 PACSIN1 PHF20 PIGC PIP4K2B PLEKHA1 PLK1S1 PNKD PPA2 PPP3R1 PTCH1 QSOX2 RAB24 RAD9A RASA2 RIN3 RP11-104H15.8 RP11-109P14.10 RP11-196G18.24 RP11-268J15.5 RP11-425D10.10 RP11-435O5.5 RP11-78I14.1 RP11-977G19.11 RPL10A RPS10 RPS20 SCMH1 SEPT2 SETD1A SMARCD2 STRADA SYNE1 TCP11 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 UBXN2A UHRF1BP1 ZBTB38 ZCCHC24 ZNF500 ZNF638 ZNF76
Trunk fat percentage 2.69 40 32 97.0 0.01 9.2e-01 AAGAB AC103965.1 ADCY3 ANP32E BCKDK C1QTNF4 CASC10 CCDC171 CENPW CTD-3076O17.1 DARS DLG1 EFEMP1 FUS GNA12 GPX1 HIST2H2AA3 HSD3B7 KANSL1 KAT8 LRRC37A LRRC37A2 NOB1 OTUD4 PACSIN1 PIAS4 RAD9A RIN3 ROM1 RP11-196G11.2 RP11-196G18.24 RP11-78I14.1 SETD1A STRADA STX4 TEAD3 UHRF1BP1 ZBTB38 ZC3H11B ZGPAT
Hand grip strength (right) 4.24 48 28 84.8 0.97 1.8e-31 ACPL2 ADAM11 ADCY3 ANGPTL1 AOC1 ARFGEF2 AXIN2 C1QTNF4 C6orf106 CCDC53 CCS CD79B CDC14B CRIPAK CYB561 CYBRD1 DARS DCAF16 DLG5 HOXB4 JAG1 JMJD4 KANSL1 L3MBTL3 LOXL1-AS1 LRRC37A LRRC37A2 MAN2C1 NCOA1 NOB1 PACSIN1 PHF20 PIP4K2B PLCD3 PPP3R1 RAD9A RASA2 RFT1 RP11-250B2.6 SCMH1 SMARCD2 STRADA TCP11 TMEM180 TP53INP2 ZBTB38 ZCCHC24 ZNF76
Townsend deprivation index at recruitment 1.40 1 0 0.0 0.00 1.0e+00 ICA1L
Current tobacco smoking 1.12 1 0 0.0 0.00 1.0e+00 ICA1L
Maternal smoking around birth 1.28 1 0 0.0 0.00 1.0e+00 CASC10
Fed-up feelings 1.36 3 2 6.1 0.00 1.0e+00 GPX1 LRRC37A LRRC37A2
Relative age voice broke 1.47 3 2 6.1 0.00 1.0e+00 LRRC37A LRRC37A2 SCMH1
Taking other prescription medications 1.34 3 0 0.0 0.00 1.0e+00 AHI1 FAIM GPX1
Age when periods started (menarche) 1.63 10 5 15.2 0.36 3.1e-01 ADCY3 C1QTNF4 CENPW GPX1 NFAT5 NOB1 NPIPA2 PSMB4 RP11-422P24.10 SAR1B
Heel bone mineral density (BMD) T-score, automated (left) 1.66 10 5 15.2 -0.36 3.1e-01 CDK6 CRIPAK DLEU2 EBPL JAG1 MRGPRF NOA1 RP11-435O5.5 SYNE1 ZNF169
High blood pressure 1.63 11 4 12.1 -0.84 6.6e-04 CDC16 CHMP1A DCAF16 FAIM FUS KAT8 PIAS4 RP11-538P18.2 SETD1A U91328.21 ZNF500
Hayfever, allergic rhinitis or eczema 1.28 4 4 12.1 -0.29 6.3e-01 AHI1 TMEM180 ZBTB38 ZGPAT
Diverticular disease/diverticulitis (self-reported) 1.25 1 0 0.0 0.00 1.0e+00 ICA1L
Medication: Levothyroxine sodium 1.16 2 1 3.0 0.00 1.0e+00 SEPT2 UHRF1BP1
Sitting height 8.81 153 134 406.1 0.92 2.2e-70 AC073834.3 AC083843.1 AC103965.1 ACPL2 ADAM11 ADCY3 ANAPC10 AOC1 ARFGEF2 ARL17B ASPSCR1 AXIN2 BMPR2 BOK C1QTNF4 C2orf52 C6orf106 C9orf102 C9orf3 CACFD1 CAMLG CCDC126 CCDC171 CCDC47 CCDC53 CD79B CDC14B CDC16 CDK6 CDO1 CENPW CEP120 CHMP1A CLK3 CMIP CPE CRIPAK CTD-3076O17.1 CXCL17 CXCR2 CYBRD1 DCAF16 DCXR DHDDS DLEU2 DLG5 DMPK DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 EPB41L2 ERCC6L2 FAIM FAM124B FAM136A GNA12 GPR126 GSDMC H1FX HIST2H2AA3 HOXB4 ICA1L ICAM2 IL23A ILF3-AS1 JAG1 JMJD4 KANSL1 KIAA1614 L3MBTL3 LEMD3 LHFPL2 LOXL1-AS1 LRRC37A LRRC37A2 MAN2C1 MPHOSPH6 MRGPRF MRPL42 MST1P2 MXD3 MYO9A NARFL NCOA1 NFAT5 NOB1 NOV OTUD4 PACSIN1 PACSIN2 PCDHB5 PHF20 PIGC PIGF PIP4K2B PLCD3 PLEKHA1 PLK1S1 PNKD PPA2 PPP3R1 PTCH1 QSOX2 RAB24 RAD9A RASA2 RFT1 RP11-104H15.8 RP11-1055B8.4 RP11-109P14.10 RP11-196G18.24 RP11-250B2.6 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-538P18.2 RP11-690I21.1 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RP1-93H18.7 RPL10A RPS10 RPS20 SAR1B SCMH1 SEPT2 SERPINF1 SLC16A9 SMARCD2 SNAI3-AS1 STRADA SYNE1 TEAD3 TMED6 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 TULP4 UBXN2A ZBTB38 ZC3H11B ZCCHC24 ZHX2 ZNF169 ZNF500 ZNF638 ZNF76 ZSWIM1
Chronic bronchitis/emphysema (father) 1.61 1 1 3.0 0.00 1.0e+00 PSMA4
Body mass index (BMI) 2.04 34 20 60.6 -0.70 3.1e-06 AC092667.2 ACHE ADCY3 ARFGEF2 BCKDK C1QTNF4 C6orf106 CASC10 CCDC171 CCS CEP120 CXCL17 CXCR2 DARS DCAF16 FUS GPX1 HSD3B7 KAT8 L3MBTL3 MST1P2 NOB1 OTUD4 PACSIN1 PIAS4 PIGF PSTPIP1 RFT1 RPS10 SAR1B SETD1A STX4 TMED6 UHRF1BP1
Impedance of leg (left) 2.54 38 26 78.8 -0.04 8.0e-01 AC103965.1 ADAM11 ADCY3 AOC1 BCKDK CCS CD79B CDK6 CDO1 CEP120 CTC-228N24.3 CTD-3076O17.1 CTSS CXCR2 CYBRD1 GPR126 GPX1 KAT8 L3MBTL3 LOXL1-AS1 LRRC37A MRGPRF MST1P2 OTUD4 PACSIN1 PHF20 PLK1S1 PPA2 PSTPIP1 PTCH1 RAD9A RIN3 RP11-382A20.2 RP11-425D10.10 RPS10 RPS20 STRADA UHRF1BP1
Leg predicted mass (left) 5.16 100 75 227.3 0.88 7.3e-38 AC083843.1 ACPL2 ADAM11 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDK BOK C2orf52 CCDC126 CCDC53 CD79B CDC14B CDC16 CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CYBRD1 DCAF16 DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 EPB41L2 FAM124B FUS GNA12 GPR126 GSDMC H1FX HIST2H2AA3 ILF3-AS1 IPO8 JMJD4 KANSL1 KAT8 KIAA1614 L3MBTL3 LHFPL2 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MXD3 NARFL NCOA1 NOV NPIPA2 OTUD4 PACSIN1 PHF20 PIGC PIP4K2B PLEKHA1 PLK1S1 PNKD PPA2 PPP3R1 PTCH1 QSOX2 RAB24 RAD9A RASA2 RIN3 RP11-104H15.8 RP11-109P14.10 RP11-196G18.24 RP11-268J15.5 RP11-425D10.10 RP11-435O5.5 RP11-78I14.1 RP11-977G19.11 RPL10A RPS10 RPS20 SCMH1 SEPT2 SETD1A SMARCD2 STRADA SYNE1 TCP11 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 UBXN2A UHRF1BP1 ZBTB38 ZCCHC24 ZNF500 ZNF638 ZNF76
Trunk fat mass 2.85 49 36 109.1 0.47 3.7e-04 AAGAB AC103965.1 ADCY3 ANAPC10 ANP32E BCKDK BOK C1QTNF4 CASC10 CCDC171 CDC16 CDK6 CEP120 CTD-3076O17.1 DLG1 E2F1 EFEMP1 EIF2AK4 FUS GNA12 GPR126 GPX1 H1FX HIST2H2AA3 HSD3B7 KANSL1 KAT8 L3MBTL3 LRRC37A LRRC37A2 MPHOSPH6 NOB1 OTUD4 PACSIN1 PHF20 PIAS4 PLEKHA1 RAD9A RASA2 RP11-196G18.24 RP11-78I14.1 RPL10A SETD1A STX4 TP53INP2 UHRF1BP1 ZBTB38 ZC3H11B ZNF500
Waist circumference 2.03 28 22 66.7 -0.07 7.1e-01 AAGAB AC092667.2 AC103965.1 ADCY3 BCKDK C1QTNF4 CASC10 CCDC171 CDK6 CEP120 FUS GNA12 HSD3B7 KAT8 NOB1 OTUD4 PACSIN1 PIAS4 RAD9A RP11-78I14.1 RPL10A RPS10 SAR1B SETD1A STX4 UHRF1BP1 ZBTB38 ZCCHC24
Number of incorrect matches in round 1.54 4 0 0.0 1.00 3.4e-03 BCKDK FUS KAT8 SETD1A
Past tobacco smoking 1.40 5 0 0.0 0.21 7.3e-01 CASC10 NOA1 NOB1 RP11-977G19.11 TMEM180
Nervous feelings 1.60 9 5 15.2 -0.41 2.8e-01 CENPW DCXR HSD3B7 KANSL1 KAT8 LRRC37A LRRC37A2 SETD1A STX4
Frequency of tenseness / restlessness in last 2 weeks 1.40 6 2 6.1 -0.84 3.8e-02 ARL17B GPX1 KANSL1 LRRC37A LRRC37A2 RP11-268J15.5
Hearing difficulty/problems with background noise 1.24 1 0 0.0 0.00 1.0e+00 LRRC37A
Hair/balding pattern: Pattern 2 1.41 3 2 6.1 0.00 1.0e+00 C10orf11 LRRC37A LRRC37A2
Had other major operations 1.42 1 0 0.0 0.00 1.0e+00 PPA2
Forced vital capacity (FVC) 11.84 230 199 603.0 1.00 1.4e-277 AAGAB AC073834.3 AC083843.1 AC092667.2 AC103965.1 ACHE ACPL2 ADAM11 ADCY3 ADO AHI1 ANAPC10 ANGPTL1 ANKRD13B ANP32E AOC1 ARFGEF2 ARL17B ASPSCR1 AXIN2 BCKDK BMPR2 BOK BRAF C10orf11 C1QTNF4 C2orf52 C2orf54 C6orf106 C9orf102 C9orf3 CACFD1 CAMLG CASC10 CATSPER1 CCDC126 CCDC171 CCDC47 CCDC53 CCS CD79B CDC14B CDC16 CDK6 CDO1 CENPW CEP120 CHMP1A CLK3 CLUAP1 CMIP CNPY2 CPE CRIPAK CTB-36H16.2 CTC-228N24.3 CTD-3076O17.1 CTSS CXCL17 CXCR2 CYB561 CYBRD1 DARS DCAF16 DCXR DHDDS DIRAS3 DLEU2 DLG1 DLG5 DMPK DPP3 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 EPB41L2 ERCC6L2 FAIM FAM124B FAM136A FER FILIP1 FOXN2 FUS GNA12 GOLGA6L5 GPR126 GPX1 GSDMC H1FX HIST2H2AA3 HOXB4 HSD3B7 ICA1L ICAM2 IL23A ILF3-AS1 INTS12 IPO8 JAG1 JMJD4 KANSL1 KAT8 KIAA1468 KIAA1614 L3MBTL3 LEMD3 LHFPL2 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 MAN2C1 MDM4 METTL22 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1P2 MXD3 MYO9A NARFL NCOA1 NFAT5 NOA1 NOB1 NOV NOX4 NPIPA2 NUDT5 OSM OTUD4 PACSIN1 PACSIN2 PCDHB5 PDE12 PECAM1 PHF20 PIAS4 PIGC PIGF PIP4K2B PLCD3 PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PPP3R1 PSMA4 PSMB4 PSTPIP1 PTCH1 QSOX2 RAB24 RAD9A RASA2 RBMS2 RFT1 RIN3 RNF123 ROM1 RP11-104H15.8 RP11-1055B8.4 RP11-109P14.10 RP11-196G11.2 RP11-196G18.24 RP11-250B2.6 RP11-268J15.5 RP11-316M1.12 RP11-382A20.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-449D8.5 RP11-538P18.2 RP11-690I21.1 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RP1-93H18.7 RPL10A RPS10 RPS20 RRP15 SAR1B SCMH1 SEPT2 SERPINF1 SETD1A SETDB1 SF3B2 SHKBP1 SLC16A9 SMARCD2 SMG7 SNAI3-AS1 STRADA STX4 SYNE1 TCP11 TEAD3 TMED6 TMEM180 TNFAIP8L3 TNFSF10 TP53INP2 TRIM63 TSEN15 TULP4 U91328.21 UBXN2A UHRF1BP1 USP14 WDR18 WHAMM XRCC5 ZBTB38 ZC3H11B ZCCHC24 ZGPAT ZHX2 ZNF169 ZNF438 ZNF500 ZNF76 ZSWIM1
Heel bone mineral density (BMD) T-score, automated (right) 1.77 10 4 12.1 -0.52 9.8e-02 CDK6 CRIPAK DLEU2 EBPL MRGPRF NOA1 RP11-435O5.5 SYNE1 ZBTB38 ZNF169
Ever unenthusiastic/disinterested for a whole week 1.24 1 0 0.0 0.00 1.0e+00 LRRC37A
Qualifications: None of the above 1.41 4 1 3.0 -0.93 7.3e-02 GPX1 PPA2 RFT1 RNF123
Mouth/teeth dental problems 1.14 2 0 0.0 0.00 1.0e+00 KANSL1 LRRC37A2
Allergy 1.31 7 5 15.2 -0.01 9.8e-01 AAGAB AHI1 GNA12 TMEM180 ZBTB38 ZGPAT ZNF76
Diabetes (self-reported) 1.59 3 1 3.0 0.00 1.0e+00 CLUAP1 MAN2C1 ZCCHC24
Medication: Simvastatin 1.48 1 0 0.0 0.00 1.0e+00 DCAF16
Fluid intelligence score 1.68 6 2 6.1 0.81 2.8e-02 C1QTNF4 DCAF16 PPA2 RNF123 U91328.21 ZNF638
Illnesses of siblings 1.55 3 0 0.0 0.00 1.0e+00 BCKDK FUS KAT8
Neuroticism score 1.73 11 8 24.2 -0.23 4.6e-01 ARL17B FUS GPX1 HSD3B7 KANSL1 LRRC37A LRRC37A2 PTCH1 RP11-196G11.2 SETD1A STX4
Weight 3.85 76 55 166.7 0.76 1.1e-16 AAGAB AC103965.1 ANAPC10 BCKDK BOK CASC10 CCDC171 CD79B CDC16 CDK6 CENPW CEP120 CRIPAK CTD-3076O17.1 CYBRD1 DCAF16 DLEU2 E2F1 EBPL EFEMP1 EIF2AK4 EPB41L2 FUS GNA12 GPR126 GPX1 GSDMC H1FX HIST2H2AA3 HSD3B7 ILF3-AS1 KANSL1 KAT8 L3MBTL3 LHFPL2 MPHOSPH6 MRGPRF MRPL42 MXD3 NARFL NPIPA2 OTUD4 PACSIN1 PHF20 PLEKHA1 PLK1S1 PPA2 RAD9A RASA2 RP11-104H15.8 RP11-196G18.24 RP11-425D10.10 RP11-435O5.5 RP11-78I14.1 RPL10A RPS10 RPS20 SCMH1 SEPT2 SERPINF1 SETD1A SMARCD2 STRADA STX4 SYNE1 TCP11 TMEM180 TP53INP2 TSEN15 UHRF1BP1 ZBTB38 ZC3H11B ZCCHC24 ZNF500 ZNF638 ZNF76
Impedance of arm (right) 2.59 44 31 93.9 0.26 6.6e-02 AAGAB AC083843.1 AC103965.1 ACHE ANP32E AOC1 ARL17B BCKDK CASC10 CD79B CENPW CEP120 CTD-3076O17.1 CYBRD1 EFEMP1 FER GPR126 GPX1 HIST2H2AA3 KANSL1 KAT8 L3MBTL3 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 MRPL42 MST1P2 PACSIN1 PHF20 PLK1S1 PPP3R1 PSTPIP1 RAD9A RFT1 RIN3 ROM1 RP11-196G18.24 RPS10 RPS20 SAR1B SCMH1 STRADA ZC3H11B
Arm fat percentage (right) 2.48 38 24 72.7 -0.71 4.5e-07 AAGAB ADCY3 ANKRD13B ARFGEF2 BCKDK BMPR2 C1QTNF4 C6orf106 CASC10 CCDC171 CCS CD79B CENPW DCAF16 DLG1 DPP3 FUS GPX1 HIST2H2AA3 HSD3B7 ICA1L KANSL1 KAT8 NFAT5 NOB1 NOV PIAS4 PIGF RP11-196G18.24 RP11-449D8.5 RP11-78I14.1 SAR1B SETD1A STRADA STX4 TEAD3 UHRF1BP1 ZNF76
Trunk fat-free mass 7.11 123 103 312.1 0.93 5.1e-59 AC083843.1 ACPL2 ADAM11 ADCY3 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDK BOK C1QTNF4 C2orf52 C6orf106 C9orf102 C9orf3 CCDC126 CCDC47 CCDC53 CD79B CDC14B CDC16 CDK6 CENPW CEP120 CHMP1A CNPY2 CRIPAK CTC-228N24.3 CXCR2 CYBRD1 DCAF16 DHDDS DLEU2 DLG1 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 EPB41L2 FAM124B FAM136A GNA12 GPR126 GSDMC H1FX ICAM2 IL23A ILF3-AS1 IPO8 JMJD4 KAT8 KIAA1614 L3MBTL3 LEMD3 LHFPL2 LOXL1-AS1 MAN2C1 MPHOSPH6 MRGPRF MRPL42 MST1P2 MXD3 MYO9A NARFL NCOA1 NOA1 NOV NOX4 NPIPA2 OTUD4 PACSIN1 PHF20 PIGC PIP4K2B PLEKHA1 PLK1S1 PNKD PPA2 PPP3R1 PTCH1 QSOX2 RAB24 RAD9A RASA2 RFT1 RIN3 RP11-104H15.8 RP11-109P14.10 RP11-250B2.6 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-690I21.1 RP11-78I14.1 RP11-977G19.11 RPL10A RPS10 RPS20 SAR1B SCMH1 SEPT2 SERPINF1 SMARCD2 SNAI3-AS1 STRADA SYNE1 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF638 ZNF76
Hip circumference 3.16 56 39 118.2 0.51 3.7e-05 AC103965.1 ADCY3 ANAPC10 BCKDK BOK C1QTNF4 CASC10 CCDC171 CD79B CDC16 CDK6 CEP120 CYBRD1 DLEU2 E2F1 EBPL EFEMP1 EIF2AK4 EPB41L2 FUS GNA12 GPR126 GPX1 H1FX HIST2H2AA3 HSD3B7 KAT8 L3MBTL3 MPHOSPH6 NARFL NOB1 OTUD4 PACSIN1 PHF20 PLEKHA1 PTCH1 RAD9A RASA2 RP11-104H15.8 RP11-196G11.2 RP11-196G18.24 RP11-425D10.10 RP11-435O5.5 RP11-78I14.1 RPL10A RPS10 RPS20 SEPT2 SETD1A STX4 TP53INP2 UHRF1BP1 ZBTB38 ZC3H11B ZNF500 ZNF76
Father's age at death 1.33 2 1 3.0 0.00 1.0e+00 GPX1 PSMA4
Worrier / anxious feelings 1.54 8 5 15.2 -0.12 7.5e-01 HSD3B7 KANSL1 LRRC37A LRRC37A2 PTCH1 SETD1A STX4 TMEM180
Frequency of tiredness / lethargy in last 2 weeks 1.20 1 0 0.0 0.00 1.0e+00 GPX1
Falls in the last year 1.24 1 0 0.0 0.00 1.0e+00 ICA1L
Hair/balding pattern: Pattern 3 1.79 5 3 9.1 0.66 2.3e-01 ARL17B CENPW KANSL1 LRRC37A LRRC37A2
Number of live births 1.00 1 0 0.0 0.00 1.0e+00 LRRC37A
Forced expiratory volume in 1-second (FEV1) 10.02 185 137 415.2 0.98 9.2e-159 AC073834.3 AC083843.1 AC092667.2 AC103965.1 ACHE ADCY3 ADO AHI1 ANAPC10 ANGPTL1 ANP32E AOC1 ARFGEF2 ARL17B ASPSCR1 AXIN2 BOK BRAF C10orf11 C1QTNF4 C2orf52 C6orf106 CACFD1 CAMLG CATSPER1 CCDC126 CCDC171 CCS CD79B CDC14B CDC16 CDK6 CDO1 CENPW CEP120 CHMP1A CLK3 CLUAP1 CMIP CRIPAK CTB-36H16.2 CTC-228N24.3 CTD-3076O17.1 CTSS CXCL17 CXCR2 CYB561 CYBRD1 DARS DCAF16 DCXR DHDDS DIRAS3 DLEU2 DLG1 DLG5 DPP3 EBPL EFEMP1 EIF2AK4 ERCC6L2 FAM136A FER FILIP1 FUS GOLGA6L5 GPX1 GSDMC H1FX HIST2H2AA3 HOXB4 HSD3B7 ICAM2 ILF3-AS1 INTS12 IPO8 JAG1 JMJD4 KANSL1 KAT8 KIAA1468 KIAA1614 L3MBTL3 LEMD3 LHFPL2 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 MAN2C1 MDM4 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1P2 MXD3 MYO9A NARFL NFAT5 NOA1 NOB1 NOV NOX4 NPIPA2 NUDT5 OSM OTUD4 PACSIN1 PCDHB5 PDE12 PECAM1 PHF20 PIAS4 PIGC PLCD3 PLEKHM1P PNKD PPA2 PSMA4 PSMB4 PTCH1 QSOX2 RAB24 RAD9A RASA2 RBMS2 RFT1 RIN3 RNF123 ROM1 RP11-1055B8.4 RP11-109P14.10 RP11-196G11.2 RP11-196G18.24 RP11-250B2.6 RP11-316M1.12 RP11-382A20.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-538P18.2 RP11-690I21.1 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RP1-93H18.7 RPL10A RPS10 RPS20 SAR1B SCMH1 SERPINF1 SETD1A SETDB1 SF3B2 SMARCD2 SMG7 SNAI3-AS1 STRADA STX4 SYNE1 TCP11 TEAD3 TMED6 TMEM180 TNFAIP8L3 TNFSF10 TP53INP2 TRIM63 TSEN15 TULP4 U91328.21 UBXN2A WHAMM XRCC5 ZBTB38 ZC3H11B ZCCHC24 ZGPAT ZHX2 ZNF169 ZNF500 ZNF76 ZSWIM1
Pulse rate 1.27 4 1 3.0 -0.17 7.8e-01 ACHE CEP120 ROM1 ZBTB38
Qualifications: A levels/AS levels or equivalent 1.50 4 2 6.1 -0.47 5.3e-01 BMPR2 GPX1 LRRC37A RNF123
Mouth/teeth dental problems: Dentures 1.36 3 0 0.0 0.00 1.0e+00 GPX1 PSMA4 RP11-1055B8.4
Asthma 1.72 7 3 9.1 -0.79 2.1e-02 AAGAB AHI1 CCS TCP11 U91328.21 ZGPAT ZNF76
Medication: Ibuprofen (e.g. Nurofen) 1.25 2 0 0.0 0.00 1.0e+00 LRRC37A U91328.21
Medication: Cholesterol lowering 1.48 1 0 0.0 0.00 1.0e+00 DCAF16
Prospective memory result 1.33 1 0 0.0 0.00 1.0e+00 ZNF638
Lung cancer (father) 1.47 1 1 3.0 0.00 1.0e+00 PSMA4
Forced expiratory volume in 1-second (FEV1), Best measure 10.31 184 127 384.8 0.99 1.2e-160 AC073834.3 AC083843.1 AC092667.2 AC103965.1 ACHE ADAM11 ADCY3 ADO AHI1 ANAPC10 ANGPTL1 AOC1 ARFGEF2 ARL17B ASPSCR1 AXIN2 BCKDK BMPR2 BOK BRAF C10orf11 C1QTNF4 C2orf52 C6orf106 CACFD1 CAMLG CATSPER1 CCDC126 CCDC171 CCS CD79B CDC14B CDC16 CDK6 CDO1 CENPW CEP120 CLK3 CLUAP1 CMIP CNPY2 CRIPAK CTB-36H16.2 CTD-3076O17.1 CTSS CXCL17 CXCR2 CYB561 CYBRD1 DARS DCAF16 DCXR DHDDS DIRAS3 DLEU2 DLG1 DLG5 DPP3 EBPL EFEMP1 ERCC6L2 FAIM FAM136A FER FILIP1 FUS GOLGA6L5 GPX1 GSDMC H1FX HOXB4 HSD3B7 ICAM2 IL23A ILF3-AS1 INTS12 IPO8 JAG1 JMJD4 KANSL1 KAT8 KIAA1468 KIAA1614 L3MBTL3 LEMD3 LHFPL2 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 MAN2C1 MDM4 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1P2 MXD3 MYO9A NFAT5 NOA1 NOB1 NOX4 NPIPA2 NUDT5 OSM OTUD4 PACSIN1 PCDHB5 PDE12 PECAM1 PHF20 PIAS4 PIGC PLCD3 PLEKHM1P PNKD PPA2 PSMA4 PSMB4 PTCH1 QSOX2 RAB24 RAD9A RASA2 RBMS2 RFT1 RIN3 RNF123 ROM1 RP11-1055B8.4 RP11-109P14.10 RP11-196G11.2 RP11-196G18.24 RP11-250B2.6 RP11-382A20.2 RP11-425D10.10 RP11-449D8.5 RP11-538P18.2 RP11-690I21.1 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RP1-93H18.7 RPL10A RPS10 RPS20 SAR1B SCMH1 SERPINF1 SETD1A SETDB1 SF3B2 SHKBP1 SMARCD2 SMG7 SNAI3-AS1 STRADA STX4 SYNE1 TCP11 TEAD3 TMED6 TMEM180 TNFAIP8L3 TNFSF10 TP53INP2 TRIM63 TSEN15 TULP4 U91328.21 UBXN2A UHRF1BP1 WHAMM XRCC5 ZBTB38 ZC3H11B ZCCHC24 ZGPAT ZHX2 ZNF169 ZNF500 ZNF76 ZSWIM1
Impedance of arm (left) 2.58 43 31 93.9 0.32 2.7e-02 AC103965.1 ACHE ANP32E AOC1 ARL17B BCKDK CASC10 CD79B CENPW CEP120 CTD-3076O17.1 CYBRD1 DLG1 EFEMP1 FER GNA12 GPR126 GPX1 HIST2H2AA3 KANSL1 KAT8 L3MBTL3 LOXL1-AS1 LRRC37A LRRC37A2 MRPL42 MST1P2 PACSIN1 PHF20 PLK1S1 PSTPIP1 RAD9A RFT1 RIN3 ROM1 RP11-196G18.24 RPS10 RPS20 SAR1B SCMH1 SHKBP1 STRADA ZC3H11B
Arm fat mass (right) 2.07 30 23 69.7 0.00 9.8e-01 AAGAB AC092667.2 ADCY3 BCKDK C1QTNF4 CASC10 CCDC171 CDK6 CEP120 FUS GNA12 GPX1 HIST2H2AA3 HSD3B7 KANSL1 KAT8 L3MBTL3 NOB1 OTUD4 PACSIN1 PIAS4 RASA2 RP11-196G18.24 RP11-78I14.1 RPS10 SETD1A STX4 TP53INP2 UHRF1BP1 ZBTB38
Trunk predicted mass 7.11 123 102 309.1 0.93 5.0e-59 AC083843.1 ACPL2 ADAM11 ADCY3 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDK BOK C1QTNF4 C2orf52 C6orf106 C9orf102 C9orf3 CCDC126 CCDC47 CCDC53 CD79B CDC14B CDC16 CDK6 CENPW CEP120 CHMP1A CNPY2 CRIPAK CTC-228N24.3 CXCR2 CYBRD1 DCAF16 DHDDS DLEU2 DLG1 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 EPB41L2 FAM124B FAM136A GNA12 GPR126 GSDMC H1FX ICAM2 IL23A ILF3-AS1 IPO8 JMJD4 KAT8 KIAA1614 L3MBTL3 LEMD3 LHFPL2 LOXL1-AS1 MAN2C1 MPHOSPH6 MRGPRF MRPL42 MST1P2 MXD3 MYO9A NARFL NCOA1 NOA1 NOV NOX4 NPIPA2 OTUD4 PACSIN1 PHF20 PIGC PIP4K2B PLEKHA1 PLK1S1 PNKD PPA2 PPP3R1 PTCH1 QSOX2 RAB24 RAD9A RASA2 RFT1 RIN3 RP11-104H15.8 RP11-109P14.10 RP11-250B2.6 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-690I21.1 RP11-78I14.1 RP11-977G19.11 RPL10A RPS10 RPS20 SAR1B SCMH1 SEPT2 SERPINF1 SMARCD2 SNAI3-AS1 STRADA SYNE1 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF638 ZNF76
Standing height 10.33 179 166 503.0 0.93 1.4e-90 AAGAB AC083843.1 AC103965.1 ACHE ACPL2 ADAM11 ADCY3 ADO ANAPC10 ANKRD13B ANP32E AOC1 ARFGEF2 ARL17B ASPSCR1 AXIN2 BMPR2 BOK BRAF C1QTNF4 C2orf52 C6orf106 C9orf102 C9orf3 CACFD1 CAMLG CATSPER1 CCDC126 CCDC47 CCDC53 CCS CD79B CDC14B CDC16 CDK6 CDO1 CENPW CEP120 CHMP1A CLK3 CMIP CNPY2 CRIPAK CTD-3076O17.1 CXCL17 CXCR2 CYB561 CYBRD1 DCAF16 DHDDS DLEU2 DLG5 DMPK DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 EPB41L2 ERCC6L2 FAIM FAM124B FAM136A FER FILIP1 GNA12 GOLGA6L5 GPR126 GPX1 GSDMC H1FX HIST2H2AA3 HOXB4 ICAM2 IL23A ILF3-AS1 IPO8 JAG1 JMJD4 KANSL1 KIAA1468 KIAA1614 L3MBTL3 LEMD3 LHFPL2 LOXL1-AS1 LRRC37A LRRC37A2 MAN2C1 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1P2 MXD3 MYO9A NARFL NCOA1 NFAT5 NOA1 NOB1 NOV NOX4 NPIPA2 OTUD4 PACSIN1 PACSIN2 PCDHB5 PECAM1 PHF20 PIAS4 PIGC PIGF PIP4K2B PLCD3 PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PPP3R1 PSMB4 PSTPIP1 PTCH1 QSOX2 RAB24 RAD9A RASA2 RFT1 RP11-104H15.8 RP11-1055B8.4 RP11-109P14.10 RP11-196G18.24 RP11-250B2.6 RP11-268J15.5 RP11-382A20.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-538P18.2 RP11-690I21.1 RP11-78I14.1 RP11-977G19.11 RP1-93H18.7 RPL10A RPS10 RPS20 RRP15 SAR1B SCMH1 SEPT2 SERPINF1 SF3B2 SLC16A9 SMARCD2 SNAI3-AS1 STRADA SYNE1 TCP11 TEAD3 TMED6 TMEM180 TNFAIP8L3 TNFSF10 TP53INP2 TRIM63 TSEN15 TULP4 U91328.21 UBXN2A ZBTB38 ZC3H11B ZCCHC24 ZHX2 ZNF169 ZNF500 ZNF638 ZNF76 ZSWIM1
Tense / 'highly strung' 1.60 7 3 9.1 0.02 9.6e-01 ANP32E FUS HSD3B7 KAT8 RP11-196G11.2 SETD1A STX4
Seen doctor (GP) for nerves, anxiety, tension or depression 1.49 2 1 3.0 0.00 1.0e+00 CCS U91328.21
Hair/balding pattern: Pattern 4 2.59 11 10 30.3 0.04 9.1e-01 ARL17B C10orf11 CENPW CTB-36H16.2 DLG5 FAM136A KANSL1 LRRC37A LRRC37A2 RASA2 ZBTB38
Birth weight of first child 2.73 11 7 21.2 0.97 1.5e-08 ANAPC10 ASPSCR1 DCAF16 DCXR IPO8 OTUD4 PPA2 RP11-78I14.1 TEAD3 ZBTB38 ZNF76
Peak expiratory flow (PEF) 4.63 47 22 66.7 0.96 1.9e-30 ANAPC10 ASPSCR1 BOK C10orf11 CACFD1 CATSPER1 CCDC53 CCS CD79B CDC14B CHMP1A DCAF16 DHDDS DLEU2 DLG1 DPP3 EBPL EFEMP1 GSDMC KANSL1 LRRC37A LRRC37A2 MDM4 MPHOSPH6 MRGPRF NOA1 NPIPA2 NUDT5 OTUD4 PDE12 PHF20 PIAS4 PNKD PPA2 RAD9A RNF123 RP11-425D10.10 RPL10A SF3B2 STRADA SYNE1 TCP11 TP53INP2 TRIM63 UBXN2A ZHX2 ZNF76
Qualifications: O levels/GCSEs or equivalent 1.23 1 1 3.0 0.00 1.0e+00 GPX1
Blood clot in the leg (DVT) 1.19 2 1 3.0 0.00 1.0e+00 CACFD1 PHF20
Medication: Paracetamol 1.56 5 4 12.1 -0.75 1.4e-01 CASC10 GPX1 LRRC37A LRRC37A2 U91328.21
Headache pain in last month 1.51 4 3 9.1 -0.82 1.8e-01 LRRC37A LRRC37A2 NOA1 U91328.21
Medication for cholesterol, blood pressure or diabetes 1.49 2 0 0.0 0.00 1.0e+00 CDC16 DCAF16
Gout (self-reported) 1.28 2 1 3.0 0.00 1.0e+00 SLC16A9 U91328.21
Hypothyroidism/myxoedema (self-reported) 1.23 6 2 6.1 -0.01 9.8e-01 AHI1 PLEKHA1 RP11-109P14.10 SEPT2 UHRF1BP1 ZNF76
Medication: Ventolin 100micrograms inhaler 1.23 1 0 0.0 0.00 1.0e+00 AAGAB
Birth weight 2.71 19 9 27.3 0.86 5.4e-07 ANAPC10 C1QTNF4 CCDC126 CDK6 CENPW CXCL17 DCAF16 GNA12 GPR126 L3MBTL3 PPA2 PTCH1 RFT1 RP11-425D10.10 RP11-435O5.5 SYNE1 TEAD3 UBXN2A ZNF76
Chronic bronchitis/emphysema (mother) 1.62 1 1 3.0 0.00 1.0e+00 PSMA4
High blood pressure (siblings) 1.50 2 1 3.0 0.00 1.0e+00 FUS KAT8
Body fat percentage 2.63 46 28 84.8 -0.37 7.6e-03 AAGAB AC073834.3 AC103965.1 ADCY3 ANKRD13B ANP32E ARFGEF2 BCKDK BMPR2 C1QTNF4 CASC10 CCDC171 CD79B CDC14B CENPW CTC-228N24.3 CTD-3076O17.1 CXCL17 DARS DCAF16 DLG1 FUS GNA12 GPX1 HIST2H2AA3 HSD3B7 KANSL1 KAT8 LRRC37A2 NOB1 NOV PIAS4 RIN3 ROM1 RP11-196G11.2 RP11-196G18.24 RP11-78I14.1 SAR1B SETD1A STRADA STX4 TEAD3 UHRF1BP1 ZBTB38 ZC3H11B ZGPAT
Leg fat percentage (right) 2.91 44 26 78.8 -0.83 3.4e-13 AAGAB AC073834.3 AC103965.1 ADCY3 ANKRD13B ARFGEF2 BCKDK BMPR2 C1QTNF4 C6orf106 CASC10 CCDC171 CD79B CDC14B CENPW CTC-228N24.3 CXCL17 DARS DCAF16 DLG1 FAM124B FOXN2 FUS GPX1 HSD3B7 ICA1L KAT8 NOB1 NOV PIAS4 PIGF PLEKHM1P RIN3 RP11-435O5.5 SAR1B SETD1A SMARCD2 SNAI3-AS1 STRADA STX4 TEAD3 UHRF1BP1 ZCCHC24 ZGPAT
Arm fat-free mass (right) 5.86 105 79 239.4 0.89 8.8e-41 AC083843.1 ACPL2 ADAM11 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDK BOK C1QTNF4 C2orf52 C6orf106 CASC10 CCDC126 CCDC53 CD79B CDC14B CDC16 CDK6 CENPW CEP120 CHMP1A CRIPAK CXCR2 CYBRD1 DCAF16 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 EPB41L2 FUS GNA12 GPR126 GPX1 GSDMC H1FX IL23A ILF3-AS1 IPO8 JMJD4 KAT8 KIAA1614 L3MBTL3 LEMD3 LHFPL2 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MXD3 NARFL NCOA1 NOV NPIPA2 OTUD4 PACSIN1 PHF20 PIGC PLEKHA1 PLK1S1 PNKD PPA2 PPP3R1 PTCH1 RAB24 RAD9A RASA2 RIN3 RP11-104H15.8 RP11-250B2.6 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-690I21.1 RP11-78I14.1 RP11-977G19.11 RPL10A RPS10 RPS20 SCMH1 SEPT2 SERPINF1 SETD1A SMARCD2 STRADA SYNE1 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZHX2 ZNF638 ZNF76
Comparative body size at age 10 2.09 14 9 27.3 -0.85 1.1e-04 ADCY3 BCKDK C1QTNF4 CATSPER1 CMIP DMPK FUS HSD3B7 KAT8 NCOA1 RP11-196G11.2 SETD1A STX4 U91328.21
Number of full brothers 1.31 1 0 0.0 0.00 1.0e+00 LRRC37A2
Worry too long after embarrassment 1.53 4 0 0.0 -0.25 7.5e-01 AHI1 LRRC37A LRRC37A2 PPA2
Wheeze or whistling in the chest in last year 1.73 3 0 0.0 0.00 1.0e+00 CCDC171 ICA1L ZGPAT
Age at first live birth 1.47 1 1 3.0 0.00 1.0e+00 GPX1
Qualifications: College or University degree 1.60 12 6 18.2 0.85 4.1e-04 DCAF16 DCXR GPX1 KANSL1 LRRC37A LRRC37A2 MDM4 PPA2 RASA2 RNF123 RP11-1055B8.4 SMARCD2
Medication for pain relief, constipation, heartburn 1.52 5 2 6.1 0.56 3.3e-01 GPX1 LRRC37A LRRC37A2 PLCD3 U91328.21
Neck or shoulder pain in last month 1.05 1 0 0.0 0.00 1.0e+00 GPX1
Medication: Blood pressure 1.50 2 1 3.0 0.00 1.0e+00 CDC16 DCAF16
Medication: Allopurinol 1.33 1 0 0.0 0.00 1.0e+00 SLC16A9
Mean time to correctly identify matches 1.39 6 2 6.1 -0.52 2.9e-01 ARFGEF2 KANSL1 L3MBTL3 LRRC37A2 PIAS4 ZNF638
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.73 1 0 0.0 0.00 1.0e+00 LRRC37A2
Whole body fat mass 2.46 42 31 93.9 0.34 1.9e-02 AAGAB AC103965.1 ADCY3 ANAPC10 ANP32E BCKDK C1QTNF4 CASC10 CCDC171 CDK6 CEP120 CTD-3076O17.1 DLG1 E2F1 EFEMP1 FUS GNA12 GPR126 GPX1 HIST2H2AA3 HSD3B7 KANSL1 KAT8 L3MBTL3 LRRC37A2 MPHOSPH6 NOB1 OTUD4 PACSIN1 PIAS4 RAD9A RASA2 RP11-196G18.24 RP11-78I14.1 RPL10A RPS10 SETD1A STX4 TP53INP2 UHRF1BP1 ZBTB38 ZC3H11B
Leg fat mass (right) 2.17 33 22 66.7 -0.04 8.4e-01 AAGAB AC103965.1 ADCY3 BCKDK C1QTNF4 CASC10 CCDC171 CDK6 CEP120 CTC-228N24.3 DARS DLG1 FUS GNA12 GPX1 HSD3B7 KAT8 L3MBTL3 MPHOSPH6 NOB1 OTUD4 PACSIN1 PIAS4 RAD9A RASA2 RP11-78I14.1 RPL10A RPS10 SAR1B SETD1A STX4 UHRF1BP1 ZBTB38
Arm predicted mass (right) 5.85 104 80 242.4 0.89 6.3e-41 AC083843.1 ACPL2 ADAM11 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDK BOK C1QTNF4 C2orf52 C6orf106 CASC10 CCDC126 CCDC53 CD79B CDC14B CDC16 CDK6 CENPW CEP120 CHMP1A CRIPAK CXCR2 CYBRD1 DCAF16 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EPB41L2 FAM124B FUS GNA12 GPR126 GPX1 GSDMC H1FX ILF3-AS1 IPO8 JMJD4 KAT8 KIAA1614 L3MBTL3 LEMD3 LHFPL2 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MXD3 NARFL NCOA1 NOV NPIPA2 OTUD4 PACSIN1 PHF20 PIGC PLEKHA1 PLK1S1 PNKD PPA2 PPP3R1 PTCH1 RAB24 RAD9A RASA2 RIN3 RP11-104H15.8 RP11-250B2.6 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-690I21.1 RP11-78I14.1 RP11-977G19.11 RPL10A RPS10 RPS20 SCMH1 SEPT2 SERPINF1 SETD1A SMARCD2 STRADA SYNE1 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZHX2 ZNF638 ZNF76
Pulse rate, automated reading 1.60 12 6 18.2 -0.23 4.4e-01 AC103965.1 ACHE CDC14B CEP120 DARS MYO9A RASA2 ROM1 RP11-1055B8.4 RP11-382A20.2 SETD1A ZBTB38
Alcohol intake frequency. 1.32 11 7 21.2 -0.96 3.0e-06 AC092667.2 C1QTNF4 KAT8 LRRC37A LRRC37A2 PACSIN2 PPA2 RP11-449D8.5 SETD1A TMED6 UBXN2A
Comparative height size at age 10 8.73 133 117 354.5 0.94 1.7e-72 AAGAB AC103965.1 ACPL2 ADAM11 ADCY3 ANAPC10 ANKRD13B ANP32E AOC1 ARFGEF2 ASPSCR1 AXIN2 BOK C1QTNF4 C6orf106 CATSPER1 CCDC126 CCDC47 CCDC53 CCS CD79B CDC14B CDC16 CDK6 CDO1 CENPW CEP120 CHMP1A CMIP CPE CRIPAK CTD-3076O17.1 CXCR2 CYBRD1 DCAF16 DHDDS DLEU2 DLG5 DMPK DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 EPB41L2 FAM124B FAM136A FER GNA12 GOLGA6L5 GPR126 GPX1 GSDMC H1FX HIST2H2AA3 HOXB4 ICAM2 ILF3-AS1 IPO8 JMJD4 KANSL1 KIAA1614 L3MBTL3 LHFPL2 LOXL1-AS1 LRRC37A LRRC37A2 MAN2C1 MPHOSPH6 MRGPRF MRPL42 MST1P2 MXD3 MYO9A NARFL NCOA1 NOV OTUD4 PACSIN1 PECAM1 PHF20 PIAS4 PIGC PIGF PIP4K2B PLCD3 PLEKHA1 PLEKHM1P PNKD PPA2 PSTPIP1 PTCH1 QSOX2 RAB24 RAD9A RASA2 RFT1 RP11-196G18.24 RP11-250B2.6 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-690I21.1 RP11-78I14.1 RP1-93H18.7 RPL10A RPS10 RPS20 SCMH1 SEPT2 SERPINF1 SLC16A9 SMARCD2 STRADA SYNE1 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 U91328.21 UBXN2A ZBTB38 ZC3H11B ZCCHC24 ZHX2 ZNF169 ZNF500 ZNF638 ZNF76
Suffer from 'nerves' 1.30 3 1 3.0 0.00 1.0e+00 C1QTNF4 KANSL1 LRRC37A2
Overall health rating 1.53 8 4 12.1 -0.97 7.5e-05 CCS DCAF16 DPP3 FUS GPX1 KAT8 RP11-1055B8.4 SETD1A
Age at last live birth 1.22 1 1 3.0 0.00 1.0e+00 GPX1
Knee pain experienced in last month 1.45 1 0 0.0 0.00 1.0e+00 PHF20
Hypertension (Self-reported) 1.67 13 5 15.2 -0.85 1.4e-04 CDC16 CHMP1A DCAF16 FUS HSD3B7 KAT8 OSM PIAS4 RP11-1055B8.4 RP11-538P18.2 SETD1A U91328.21 ZNF500
Illnesses of father: Heart disease 1.35 1 0 0.0 0.00 1.0e+00 ZCCHC24
Forced expiratory volume in 1-second (FEV1), predicted 7.57 68 42 127.3 0.97 4.2e-53 AC103965.1 ACHE ADCY3 ANAPC10 ANP32E BOK C1QTNF4 C6orf106 CD79B CDC16 CDK6 CENPW CHMP1A CNPY2 CTD-3076O17.1 CYBRD1 DCAF16 DLEU2 E2F1 EBPL EFEMP1 GNA12 GPR126 GSDMC H1FX HIST2H2AA3 HOXB4 IL23A ILF3-AS1 JMJD4 L3MBTL3 LEMD3 LOXL1-AS1 MAN2C1 MPHOSPH6 MRPL42 MST1P2 MYO9A NARFL OTUD4 PACSIN1 PHF20 PIP4K2B PTCH1 RAB24 RAD9A RASA2 RFT1 RP11-196G18.24 RP11-435O5.4 RP11-435O5.5 RP11-690I21.1 RP11-977G19.11 RPL10A SCMH1 SLC16A9 SMARCD2 STRADA TCP11 TEAD3 TMEM180 TP53INP2 TSEN15 ZBTB38 ZHX2 ZNF500 ZNF638 ZNF76
Whole body fat-free mass 6.35 114 96 290.9 0.91 1.8e-51 AC083843.1 ACPL2 ADAM11 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDK BOK C1QTNF4 C2orf52 C6orf106 C9orf102 CCDC126 CCDC47 CCDC53 CD79B CDC14B CDC16 CDK6 CENPW CEP120 CHMP1A CNPY2 CRIPAK CTC-228N24.3 CXCR2 CYBRD1 DCAF16 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 EPB41L2 FAM124B GNA12 GPR126 GSDMC H1FX IL23A ILF3-AS1 IPO8 JMJD4 KAT8 KIAA1614 L3MBTL3 LEMD3 LHFPL2 LOXL1-AS1 MAN2C1 MPHOSPH6 MRGPRF MRPL42 MXD3 NARFL NCOA1 NOV NPIPA2 OTUD4 PACSIN1 PHF20 PIGC PIP4K2B PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PPP3R1 PTCH1 QSOX2 RAB24 RAD9A RASA2 RIN3 RP11-104H15.8 RP11-109P14.10 RP11-250B2.6 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-690I21.1 RP11-78I14.1 RP11-977G19.11 RPL10A RPS10 RPS20 SCMH1 SEPT2 SERPINF1 SETD1A SMARCD2 SNAI3-AS1 STRADA SYNE1 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF638 ZNF76
Leg fat-free mass (right) 5.28 103 80 242.4 0.89 3.9e-41 AC083843.1 ACPL2 ADAM11 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDK BOK C2orf52 C9orf102 CCDC126 CCDC53 CD79B CDC14B CDC16 CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CYBRD1 DCAF16 DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 EPB41L2 FAM124B GNA12 GPR126 GSDMC H1FX HIST2H2AA3 ILF3-AS1 IPO8 JMJD4 KANSL1 KAT8 KIAA1614 L3MBTL3 LHFPL2 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MXD3 NARFL NCOA1 NOV NPIPA2 OTUD4 PACSIN1 PHF20 PIP4K2B PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PPP3R1 PTCH1 QSOX2 RAB24 RAD9A RASA2 RIN3 RP11-104H15.8 RP11-109P14.10 RP11-196G18.24 RP11-250B2.6 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-78I14.1 RP11-977G19.11 RPL10A RPS10 RPS20 SCMH1 SEPT2 SETD1A SMARCD2 SNAI3-AS1 STRADA SYNE1 TCP11 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 UBXN2A UHRF1BP1 ZBTB38 ZCCHC24 ZNF500 ZNF638 ZNF76
Arm fat percentage (left) 2.49 39 24 72.7 -0.68 1.4e-06 AAGAB ADCY3 ANKRD13B ARFGEF2 BCKDK BMPR2 C1QTNF4 C6orf106 CASC10 CCDC171 CCS CD79B CENPW DCAF16 DLG1 DPP3 FUS GNA12 GPX1 HIST2H2AA3 HSD3B7 ICA1L KANSL1 KAT8 NFAT5 NOB1 NOV PIAS4 PIGF RP11-196G18.24 RP11-449D8.5 RP11-78I14.1 SAR1B SETD1A STRADA STX4 TEAD3 UHRF1BP1 ZNF76
Handedness (chirality/laterality): Left-handed 1.45 4 3 9.1 1.00 1.6e-04 ARL17B KANSL1 LRRC37A LRRC37A2
Mood swings 1.45 4 4 12.1 -0.95 4.7e-02 GPX1 KANSL1 LRRC37A LRRC37A2
Loneliness, isolation 1.46 3 1 3.0 0.00 1.0e+00 ARFGEF2 C1QTNF4 GPX1
Long-standing illness, disability or infirmity 1.38 3 1 3.0 0.00 1.0e+00 CCDC171 NOB1 ZGPAT
Diabetes diagnosed by doctor 1.63 2 1 3.0 0.00 1.0e+00 CENPW ZCCHC24
Qualifications: nursing, teaching 1.21 1 0 0.0 0.00 1.0e+00 AXIN2
Mouth/teeth dental problems: Mouth ulcers 1.48 3 3 9.1 0.00 1.0e+00 CTSS LRRC37A LRRC37A2
Medication for cholesterol 1.66 3 0 0.0 0.00 1.0e+00 CHMP1A KAT8 ZNF500
Asthma (self-reported) 1.67 6 3 9.1 -0.73 6.4e-02 AAGAB AHI1 CCS TCP11 U91328.21 ZNF76
Osteoporosis (self-reported) 1.12 1 0 0.0 0.00 1.0e+00 MRGPRF
Smoking status: Current 1.14 2 0 0.0 0.00 1.0e+00 CCDC53 ICA1L
Forced expiratory volume in 1-second (FEV1), predicted percentage 4.60 46 26 78.8 0.91 1.3e-18 AC073834.3 ADO ANGPTL1 ARL17B ASPSCR1 BCKDK BOK C10orf11 CEP120 CLUAP1 CTSS DHDDS FUS GPR126 HSD3B7 INTS12 JAG1 KANSL1 KAT8 LRRC37A LRRC37A2 NOB1 NUDT5 OSM PDE12 PPA2 PSMA4 QSOX2 RIN3 RNF123 ROM1 RP11-196G11.2 RP11-250B2.6 RP11-382A20.2 RP11-538P18.2 RP11-967K21.1 RP1-93H18.7 RPL10A SETD1A STX4 TCP11 TRIM63 U91328.21 WHAMM ZGPAT ZNF76
Whole body water mass 6.30 112 96 290.9 0.92 6.2e-51 AC083843.1 ACPL2 ADAM11 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDK BOK C1QTNF4 C2orf52 C6orf106 C9orf102 CCDC126 CCDC53 CD79B CDC14B CDC16 CDK6 CENPW CEP120 CHMP1A CNPY2 CRIPAK CTC-228N24.3 CXCR2 CYBRD1 DCAF16 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 EPB41L2 FAM124B GNA12 GPR126 GSDMC H1FX IL23A ILF3-AS1 IPO8 JMJD4 KAT8 KIAA1614 L3MBTL3 LEMD3 LHFPL2 LOXL1-AS1 MAN2C1 MPHOSPH6 MRGPRF MRPL42 MXD3 NARFL NCOA1 NOV NPIPA2 OTUD4 PACSIN1 PHF20 PIGC PIP4K2B PLEKHA1 PLK1S1 PNKD PPA2 PPP3R1 PTCH1 QSOX2 RAB24 RAD9A RASA2 RIN3 RP11-104H15.8 RP11-109P14.10 RP11-250B2.6 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-690I21.1 RP11-78I14.1 RP11-977G19.11 RPL10A RPS10 RPS20 SCMH1 SEPT2 SERPINF1 SETD1A SMARCD2 SNAI3-AS1 STRADA SYNE1 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF638 ZNF76
Leg predicted mass (right) 5.29 103 80 242.4 0.90 4.1e-41 AC083843.1 ACPL2 ADAM11 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDK BOK C2orf52 C9orf102 CCDC126 CCDC53 CD79B CDC14B CDC16 CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CYBRD1 DCAF16 DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 EPB41L2 FAM124B GNA12 GPR126 GSDMC H1FX HIST2H2AA3 ILF3-AS1 IPO8 JMJD4 KANSL1 KAT8 KIAA1614 L3MBTL3 LHFPL2 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MXD3 NARFL NCOA1 NOV NPIPA2 OTUD4 PACSIN1 PHF20 PIP4K2B PLEKHA1 PLEKHM1P PLK1S1 PNKD PPA2 PPP3R1 PTCH1 QSOX2 RAB24 RAD9A RASA2 RIN3 RP11-104H15.8 RP11-109P14.10 RP11-196G18.24 RP11-250B2.6 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-78I14.1 RP11-977G19.11 RPL10A RPS10 RPS20 SCMH1 SEPT2 SETD1A SMARCD2 SNAI3-AS1 STRADA SYNE1 TCP11 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 UBXN2A UHRF1BP1 ZBTB38 ZCCHC24 ZNF500 ZNF638 ZNF76
Arm fat mass (left) 2.11 31 22 66.7 0.08 6.8e-01 AAGAB ADCY3 BCKDK C1QTNF4 CASC10 CCDC171 CDK6 CEP120 FUS GNA12 GPX1 HIST2H2AA3 HSD3B7 KANSL1 KAT8 L3MBTL3 NOB1 OTUD4 PACSIN1 PIAS4 RAD9A RASA2 RP11-196G18.24 RP11-78I14.1 RPL10A RPS10 SETD1A STX4 TP53INP2 UHRF1BP1 ZBTB38
Number of self-reported non-cancer illnesses 1.75 2 1 3.0 0.00 1.0e+00 AAGAB CCS
Average weekly champagne plus white wine intake 1.20 1 0 0.0 0.00 1.0e+00 LRRC37A
Miserableness 1.34 4 2 6.1 -0.94 6.4e-02 GPX1 LOXL1-AS1 LRRC37A LRRC37A2
Guilty feelings 1.48 2 0 0.0 0.00 1.0e+00 LRRC37A UBXN2A
Financial situation satisfaction 1.17 1 1 3.0 0.00 1.0e+00 GPX1
Medication: Blood pressure 1.56 6 3 9.1 0.01 9.9e-01 CHMP1A KAT8 LRRC37A RP11-1055B8.4 ZGPAT ZNF500
Supplements: Fish oil (including cod liver oil) 1.23 1 0 0.0 0.00 1.0e+00 NFAT5
High cholesterol (Self-reported) 1.66 4 0 0.0 -1.00 4.2e-03 FAM136A FUS ICA1L SETD1A
Medication: Bendroflumethiazide 1.26 2 0 0.0 0.00 1.0e+00 CHMP1A KAT8
Medication: Paracetamol 1.51 5 3 9.1 -0.84 7.6e-02 CASC10 GPX1 LRRC37A LRRC37A2 U91328.21
Ever smoked 1.29 3 0 0.0 0.00 1.0e+00 NOA1 PSMA4 TMEM180
Basal metabolic rate 5.77 109 86 260.6 0.89 2.7e-42 AC083843.1 ACPL2 ADAM11 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDK BOK C2orf52 CCDC126 CCDC53 CD79B CDC14B CDC16 CDK6 CENPW CEP120 CHMP1A CRIPAK CTC-228N24.3 CXCR2 CYBRD1 DCAF16 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 EPB41L2 FAM124B FUS GNA12 GPR126 GPX1 GSDMC H1FX ILF3-AS1 IPO8 JMJD4 KANSL1 KAT8 KIAA1614 L3MBTL3 LEMD3 LHFPL2 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MXD3 NARFL NCOA1 NOV NPIPA2 OTUD4 PACSIN1 PHF20 PIGC PIP4K2B PLEKHA1 PLK1S1 PNKD PPA2 PPP3R1 PTCH1 QSOX2 RAB24 RAD9A RASA2 RIN3 RP11-104H15.8 RP11-109P14.10 RP11-250B2.6 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-690I21.1 RP11-78I14.1 RP11-977G19.11 RPL10A RPS10 RPS20 SCMH1 SEPT2 SERPINF1 SETD1A SMARCD2 STRADA SYNE1 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 UBXN2A UHRF1BP1 ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF638 ZNF76
Leg fat percentage (left) 2.90 44 28 84.8 -0.86 2.7e-14 AAGAB AC073834.3 AC103965.1 ADCY3 ANKRD13B ARFGEF2 BCKDK BMPR2 C1QTNF4 C6orf106 CASC10 CCDC171 CD79B CDC14B CENPW CTC-228N24.3 CXCL17 DARS DCAF16 DLG1 FOXN2 FUS GPX1 HSD3B7 ICA1L KAT8 NOB1 NOV PIAS4 PIGF PLEKHM1P RFT1 RIN3 RP11-435O5.5 SAR1B SETD1A SMARCD2 STRADA STX4 TEAD3 UHRF1BP1 ZCCHC24 ZGPAT ZNF76
Arm fat-free mass (left) 5.61 103 78 236.4 0.88 1.4e-38 AC083843.1 ACPL2 ADAM11 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDK BOK C1QTNF4 C2orf52 CASC10 CCDC126 CCDC53 CD79B CDC14B CDC16 CDK6 CENPW CEP120 CHMP1A CRIPAK CXCR2 CYBRD1 DCAF16 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 EPB41L2 FUS GNA12 GPR126 GPX1 GSDMC H1FX ILF3-AS1 IPO8 JMJD4 KAT8 KIAA1614 L3MBTL3 LEMD3 LHFPL2 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MXD3 NARFL NCOA1 NOV NPIPA2 OTUD4 PACSIN1 PHF20 PIGC PLEKHA1 PLK1S1 PNKD PPA2 PPP3R1 PTCH1 RAB24 RAD9A RASA2 RIN3 RP11-104H15.8 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-690I21.1 RP11-78I14.1 RP11-977G19.11 RPL10A RPS10 RPS20 SCMH1 SEPT2 SERPINF1 SETD1A SMARCD2 STRADA SYNE1 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF638 ZNF76
Number of operations (self-reported) 1.78 4 2 6.1 -0.10 9.0e-01 CASC10 CCDC126 GNA12 PPA2
Average weekly beer plus cider intake 1.01 1 0 0.0 0.00 1.0e+00 RNF123
Irritability 1.58 9 4 12.1 -0.40 2.9e-01 FUS GPX1 HSD3B7 L3MBTL3 LRRC37A LRRC37A2 RP11-196G11.2 SETD1A STX4
Ever had prostate specific antigen (PSA) test 1.36 1 0 0.0 0.00 1.0e+00 ZBTB38
Fractured/broken bones in last 5 years 1.45 1 0 0.0 0.00 1.0e+00 AAGAB
Diastolic blood pressure, automated reading 1.88 23 11 33.3 -0.40 4.9e-02 AAGAB ACPL2 ADO CASC10 CDC16 CEP120 CHMP1A DARS DCAF16 FUS GPX1 HSD3B7 JAG1 KAT8 MYO9A NOV PDE12 PECAM1 RP11-538P18.2 SCMH1 SETD1A U91328.21 ZGPAT
Myopia 1.44 1 1 3.0 0.00 1.0e+00 QSOX2
Vascular/heart problems diagnosed by doctor 1.73 15 5 15.2 0.76 5.8e-04 AAGAB BCKDK CHMP1A DCAF16 FAIM FUS KAT8 NFAT5 OSM PIAS4 RP11-1055B8.4 RP11-538P18.2 SETD1A TEAD3 ZNF500
Cholesterol lowering medication 1.76 5 0 0.0 -1.00 2.0e-04 ANKRD13B FUS ICA1L SETD1A STX4
Pain experienced in last month 1.54 6 1 3.0 0.93 6.8e-03 CENPW FUS GPX1 KANSL1 LRRC37A2 STX4
Deep venous thrombosis (DVT) (self-reported) 1.16 2 1 3.0 0.00 1.0e+00 CACFD1 PHF20
Heart disease (siblings) 1.33 1 0 0.0 0.00 1.0e+00 TP53INP2
Pack years of smoking 2.16 4 1 3.0 -0.86 1.4e-01 CYB561 GPX1 PIAS4 PSMA4
Impedance of whole body 2.50 47 35 106.1 0.14 3.2e-01 AC083843.1 AC103965.1 ACHE ADCY3 ANP32E AOC1 ARL17B BCKDK CCS CD79B CENPW CEP120 CTC-228N24.3 CTD-3076O17.1 CYBRD1 EFEMP1 FER GPR126 GPX1 HIST2H2AA3 KANSL1 KAT8 L3MBTL3 LOXL1-AS1 LRRC37A LRRC37A2 MRGPRF MRPL42 MST1P2 OTUD4 PACSIN1 PHF20 PLK1S1 PPA2 PSTPIP1 RAD9A RFT1 RIN3 ROM1 RP11-196G18.24 RP11-382A20.2 RP11-425D10.10 RPS10 RPS20 SCMH1 STRADA UHRF1BP1
Leg fat mass (left) 2.15 34 22 66.7 -0.03 8.7e-01 AAGAB AC103965.1 ADCY3 BCKDK C1QTNF4 CASC10 CCDC171 CDK6 CEP120 CTC-228N24.3 DARS DLG1 FUS GNA12 GPX1 HSD3B7 KAT8 L3MBTL3 MPHOSPH6 NOB1 OTUD4 PACSIN1 PIAS4 RAD9A RASA2 RP11-78I14.1 RPL10A RPS10 SAR1B SETD1A STX4 UHRF1BP1 ZBTB38 ZC3H11B
Arm predicted mass (left) 5.57 103 77 233.3 0.88 1.4e-38 AC083843.1 ACPL2 ADAM11 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDK BOK C2orf52 CASC10 CCDC126 CCDC53 CD79B CDC14B CDC16 CDK6 CENPW CEP120 CHMP1A CRIPAK CXCR2 CYBRD1 DCAF16 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 EPB41L2 FUS GNA12 GPR126 GPX1 GSDMC H1FX ILF3-AS1 IPO8 JMJD4 KAT8 KIAA1614 L3MBTL3 LEMD3 LHFPL2 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MXD3 NARFL NCOA1 NOV NPIPA2 OTUD4 PACSIN1 PHF20 PIGC PLEKHA1 PLK1S1 PNKD PPA2 PPP3R1 PTCH1 RAB24 RAD9A RASA2 RIN3 RP11-104H15.8 RP11-250B2.6 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-690I21.1 RP11-78I14.1 RP11-977G19.11 RPL10A RPS10 RPS20 SCMH1 SEPT2 SERPINF1 SETD1A SMARCD2 STRADA SYNE1 TCP11 TEAD3 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 UBXN2A ZBTB38 ZCCHC24 ZHX2 ZNF500 ZNF638 ZNF76

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 66 1.89 3.83
GTEx Adipose Visceral Omentum 43 2.11 4.15
GTEx Adrenal Gland 30 2.06 3.78
GTEx Artery Aorta 56 1.88 4.02
GTEx Artery Coronary 28 2.37 4.38
GTEx Artery Tibial 83 2.21 3.89
GTEx Brain Caudate basal ganglia 13 1.41 3.64
GTEx Brain Cerebellar Hemisphere 36 2.42 4.11
GTEx Brain Cerebellum 43 2.17 4.01
GTEx Brain Cortex 27 2.61 4.19
GTEx Brain Frontal Cortex BA9 16 1.73 4.04
GTEx Brain Hippocampus 15 2.86 4.48
GTEx Brain Hypothalamus 17 2.88 4.35
GTEx Brain Nucleus accumbens basal ganglia 20 2.31 4.35
GTEx Brain Putamen basal ganglia 9 1.44 3.88
GTEx Breast Mammary Tissue 38 1.93 4.09
GTEx Breast Mammary Tissue (Male) 32 2.68 4.48
GTEx Breast Mammary Tissue (Female) 29 1.76 3.87
GTEx Cells EBV-transformed lymphocytes 36 2.53 4.44
GTEx Cells Transformed fibroblasts 73 1.74 3.70
GTEx Colon Sigmoid 28 1.92 4.06
GTEx Colon Transverse 43 2.08 3.93
GTEx Esophagus Gastroesophageal Junction 31 2.15 4.11
GTEx Esophagus Mucosa 70 2.11 3.91
GTEx Esophagus Muscularis 67 2.07 4.13
GTEx Heart Atrial Appendage 40 2.53 4.34
GTEx Heart Left Ventricle 25 1.63 3.91
GTEx Liver 20 2.79 4.22
GTEx Lung 70 2.44 3.97
GTEx Muscle Skeletal 47 1.63 3.72
GTEx Nerve Tibial 84 1.94 3.83
GTEx Ovary 26 2.86 4.94
GTEx Pancreas 33 2.02 3.94
GTEx Pituitary 33 2.96 4.49
GTEx Prostate 16 1.92 3.88
GTEx Skin Not Sun Exposed Suprapubic 51 2.07 3.94
GTEx Skin Sun Exposed Lower leg 72 1.98 3.98
GTEx Small Intestine Terminal Ileum 13 2.82 4.68
GTEx Spleen 30 2.13 4.14
GTEx Stomach 36 2.48 4.14
GTEx Testis 71 2.25 4.07
GTEx Thyroid 69 1.73 3.88
GTEx Uterus 16 2.82 4.75
GTEx Vagina 16 2.52 4.05
GTEx Whole Blood 42 2.11 3.78
METSIM Adipose 59 1.28 3.21
NTR Blood 36 1.50 3.21
ROSMAP Brain Pre-frontal Cortex 56 1.28 3.24
YFS Blood 54 1.17 3.11
CommonMind Brain Pre-frontal Cortex 69 1.28 3.16
TCGA Breast Tumor 14 1.83 3.72
TCGA Breast Normal 49 1.16 2.91
TCGA Ovarian Tumor 37 1.27 3.15
TCGA Prostate Tumor 41 1.19 3.26