Hub : Traits :

Forced vital capacity (FVC)

2358 significantly associated models · 575 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 16102124 18461490 17 1 9.1e-31 3.1e-32 1.8e-03 93 MST1P2
2 1 25475418 27971502 8 3 2.9e-14 1.6e-12 1.4e-01 96 DHDDS NUDC TRIM63
3 1 36115139 37494602 1 1 3.4e-07 2.3e-06 1.0e+00 100 RP11-268J15.5
4 1 37628741 39186794 3 1 2.0e-07 1.1e-07 4.8e-02 86 FHL3
5 1 40748755 42542658 4 1 1.0e-21 3.1e-24 7.5e-06 81 SCMH1
6 1 67814420 69212053 1 1 4.0e-08 3.7e-08 5.2e-02 88 DIRAS3
7 1 149672809 152070472 19 9 1.3e-15 8.7e-17 8.4e-127 -729 ANP32E CTSS HIST2H2AA3 PSMB4 RP11-196G18.22 RP11-196G18.24 RP11-316M1.12 SETDB1
8 1 154462360 155829511 1 1 5.9e-08 2.1e-08 1.0e+00 100 MUC1
9 1 178129899 179534540 1 1 3.6e-09 3.3e-10 2.4e-02 87 ANGPTL1
10 1 180186713 181614143 1 1 1.4e-09 9.6e-10 1.0e+00 100 KIAA1614
11 1 183325796 184739300 1 1 3.6e-07 3.1e-07 1.0e-06 9 TSEN15
12 1 203692179 205241659 2 1 9.4e-10 2.3e-11 1.1e-03 76 MDM4
13 1 217760821 220479607 2 2 2.5e-10 4.4e-16 1.2e-17 -11 RRP15 ZC3H11B
14 1 226488826 228663659 3 1 2.4e-11 1.8e-10 1.4e-01 95 JMJD4
15 2 23453834 25889403 9 11 9.9e-23 2.8e-21 NaN NaN ADCY3 CENPO DNAJC27 FKBP1B NCOA1 RP11-443B20.1 TP53I3 UBXN2A
16 2 35883253 37567226 5 1 4.8e-12 1.3e-11 6.6e-04 75 RP11-78I14.1
17 2 46117914 47538477 1 1 1.5e-08 5.2e-10 9.7e-03 83 PIGF
18 2 54817683 56843605 3 2 4.8e-53 3.1e-69 2.1e-09 88 EFEMP1
19 2 69678079 71228388 4 1 6.5e-12 6.9e-10 1.5e-03 74 FAM136A
20 2 100029106 101629737 2 1 3.2e-08 2.7e-08 1.1e-03 66 AC092667.2
21 2 134794256 137435625 5 1 3.7e-12 2.4e-11 1.5e-04 68 DARS
22 2 171478402 173114238 2 1 5.4e-12 2.8e-08 1.2e-02 80 CYBRD1
23 2 177559549 179672547 4 1 4.9e-12 1.2e-10 1.5e-01 95 AC073834.3
24 2 202434393 204433184 4 2 3.7e-08 3.6e-08 3.7e-03 72 ICA1L NOP58
25 2 218300530 220374137 9 2 1.4e-14 7.0e-10 1.2e-08 14 CXCR2 PNKD
26 2 231628878 233349588 4 2 1.4e-10 1.7e-09 4.7e-03 78 LINC00471 RP11-690I21.1
27 2 241133660 243048760 8 6 3.1e-23 9.4e-19 3.5e-24 -32 BOK C2orf54 FARP2 PASK SEPT2
28 3 32497274 33950934 1 1 1.2e-10 3.9e-11 1.2e-09 15 SUSD5
29 3 48702606 50448632 2 1 7.5e-08 5.8e-07 5.5e-04 52 RNF123
30 3 52166147 53560321 1 1 1.4e-07 2.0e-06 1.0e+00 100 RP5-966M1.6
31 3 56843028 58241059 1 1 7.0e-09 2.5e-09 7.9e-03 80 PDE12
32 3 71029408 72501994 1 1 4.1e-07 8.7e-13 4.2e-07 50 EIF4E3
33 3 128107020 129714372 3 2 4.7e-11 4.0e-14 1.9e-04 76 H1FX RAB43
34 3 140250247 142017527 3 4 6.2e-24 1.5e-24 1.0e+00 100 ACPL2 RASA2 ZBTB38
35 3 157125828 159106064 4 1 4.6e-22 4.5e-19 4.3e-03 90 RP11-538P18.2
36 3 171529470 172924003 1 1 1.1e-07 3.7e-14 3.4e-09 39 TNFSF10
37 3 196072442 197724684 1 2 3.4e-09 3.0e-10 1.7e-01 95 DLG1
38 4 673778 2058475 2 1 3.4e-09 1.7e-06 4.3e-01 97 CRIPAK
39 4 2233366 4219590 2 3 5.0e-09 2.9e-11 1.4e-05 57 LRPAP1 MFSD10
40 4 17104059 18533844 2 2 4.9e-46 5.4e-41 1.4e-03 94 DCAF16
41 4 57080198 58531645 3 1 2.2e-10 3.4e-10 1.9e-01 96 NOA1
42 4 76660500 78402379 1 1 8.9e-09 3.2e-12 5.3e-05 66 SHROOM3
43 4 105373669 107622327 5 2 7.4e-17 2.3e-19 2.0e-02 93 INTS12 PPA2
44 4 144758204 146788825 5 2 1.5e-31 2.6e-30 9.1e-01 100 ANAPC10 OTUD4
45 5 77083651 78753539 1 1 1.7e-12 7.9e-23 5.3e-13 46 LHFPL2
46 5 107390303 109224099 1 1 3.7e-11 7.2e-13 2.4e-05 65 FER
47 5 114443019 115851911 1 1 1.2e-08 2.8e-09 5.1e-02 89 CDO1
48 5 121480516 123449266 2 2 1.5e-12 4.5e-13 4.1e-01 99 CEP120 CTB-36H16.2
49 5 126587995 128220643 2 1 8.0e-10 3.3e-09 3.3e-03 75 CTC-228N24.3
50 5 133164490 134935530 4 3 1.4e-12 1.6e-09 2.8e-02 87 CAMLG SAR1B
51 5 139348915 141214127 8 1 9.5e-09 2.8e-07 8.3e-01 100 ZMAT2
52 5 147825590 149338157 1 1 6.4e-08 9.9e-08 1.0e+00 100 ABLIM3
53 5 175662866 177260129 5 3 3.6e-13 1.0e-12 6.2e-02 93 MXD3 RAB24 UIMC1
54 6 25285943 26689223 1 1 1.7e-13 3.4e-13 1.2e-05 64 U91328.21
55 6 33662667 36581149 14 8 2.3e-20 3.4e-32 NaN NaN C6orf106 PACSIN1 RPL10A ZNF76
56 6 75319716 77324522 3 1 1.7e-10 1.3e-08 2.4e-01 96 FILIP1
57 6 80120201 81763771 2 1 1.6e-11 1.2e-11 2.5e-03 80 BCKDHB
58 6 108994161 110844259 8 1 3.8e-14 3.4e-14 1.0e+00 100 RP11-425D10.10
59 6 115880851 117481404 3 1 3.5e-09 7.5e-10 1.0e-02 83 FAM26F
60 6 125970401 127355237 1 1 8.9e-31 4.6e-33 5.2e-04 92 CENPW
61 6 129638583 132080991 3 2 6.3e-26 4.5e-27 9.0e-15 48 EPB41L2 RP11-73O6.3
62 6 134905567 136516257 2 1 8.9e-09 2.7e-09 4.1e-03 77 AHI1
63 6 141924760 143855272 2 1 8.9e-30 1.5e-31 1.0e+00 100 GPR126
64 6 151743948 153655470 1 1 6.6e-11 9.8e-12 1.3e-06 49 SYNE1
65 6 158041511 159632250 1 1 1.0e-10 2.3e-11 1.0e+00 100 TULP4
66 7 2032803 3581391 2 1 1.0e-12 3.2e-12 2.3e-02 89 GNA12
67 7 22449883 24382726 2 2 2.3e-11 1.9e-21 1.1e-07 69 CCDC126 KLHL7
68 7 45255940 46658015 1 1 1.9e-08 3.8e-13 1.6e-11 14 IGFBP3
69 7 91380845 93160671 4 2 3.8e-13 3.8e-12 1.1e-01 95 AC007566.10 CDK6
70 7 99792666 101185166 1 1 4.6e-09 5.4e-06 1.1e-01 87 ACHE
71 7 139700516 141413051 5 2 1.1e-10 9.4e-11 1.0e+00 100 BRAF NDUFB2
72 7 149847287 151252618 1 1 1.2e-09 7.8e-13 2.0e-05 65 AOC1
73 8 56269387 57683880 2 1 2.1e-13 5.7e-23 2.3e-11 54 RPS20
74 8 119737284 121136001 1 1 1.5e-10 2.2e-10 3.5e-09 14 NOV
75 8 123101743 124679448 1 1 6.8e-10 1.6e-10 6.3e-03 82 ZHX2
76 8 130062993 131498180 1 1 1.0e-15 5.9e-18 1.1e-06 68 GSDMC
77 9 14857740 16758776 1 1 1.9e-13 9.4e-14 6.4e-02 94 CCDC171
78 9 96326127 100114913 13 8 5.0e-22 1.7e-28 1.1e-03 91 C9orf3 ERCC6L2 HSD17B3 PTCH1 RP11-435O5.4 RP11-435O5.5 ZNF169
79 9 100871717 102304304 1 1 2.7e-08 1.4e-08 3.0e-06 32 GALNT12
80 9 126927285 128610269 2 1 6.5e-08 5.9e-07 4.4e-02 84 PRPS1P2
81 9 135521303 137034272 2 1 2.1e-08 2.2e-11 1.1e-04 67 CACFD1
82 9 138403706 139836362 1 1 2.6e-21 8.0e-20 1.0e-01 97 QSOX2
83 10 11515875 12989666 2 1 5.6e-10 1.8e-10 1.8e-02 86 NUDT5
84 10 28113533 29610861 2 1 7.4e-08 3.1e-10 9.9e-11 -6 WAC-AS1
85 10 74317852 76266883 3 2 9.9e-08 9.5e-08 1.0e+00 100 DNAJC9-AS1 NDST2
86 10 76664253 80383574 3 2 4.3e-09 8.5e-11 4.2e-04 70 C10orf11 DLG5
87 10 80443273 82307117 4 1 2.6e-11 2.3e-07 1.1e-02 76 ZCCHC24
88 10 88156839 89647154 1 1 3.1e-07 6.3e-06 8.2e-01 100 FAM35A
89 10 101975269 103362569 1 1 7.1e-09 1.3e-08 1.0e+00 100 RP11-179B2.2
90 10 103527782 105275242 4 1 3.1e-10 2.3e-07 9.4e-01 100 TMEM180
91 10 123438113 124889817 1 1 2.3e-09 2.8e-24 1.5e-18 25 PLEKHA1
92 11 32365430 33815975 2 1 1.2e-10 1.2e-08 7.7e-02 90 TCP11L1
93 11 46064974 48783497 18 6 7.3e-13 3.9e-11 1.0e+00 100 C1QTNF4 DDB2 MTCH2 RAPSN Y_RNA
94 11 61627881 63078986 4 1 6.7e-08 2.8e-08 1.7e-07 11 ROM1
95 11 64663227 69549801 21 11 1.3e-38 2.5e-35 1.0e+00 100 CCS CTD-3074O7.12 DPP3 KCNK7 MRGPRF RAD9A RBM4 SF3B2 TPCN2
96 11 76827992 78323351 2 1 1.8e-08 5.0e-06 3.0e-01 95 AP000580.1
97 11 88358544 89851689 1 1 1.1e-07 2.8e-08 8.4e-02 90 NOX4
98 11 116022447 117662909 1 1 1.8e-07 1.9e-10 2.6e-06 45 SIK3
99 11 117923358 119659753 2 2 6.8e-09 2.2e-08 1.0e+00 100 DDX6 HMBS
100 12 403545 2299048 1 1 2.3e-08 5.1e-11 1.3e-06 46 ERC1
101 12 14261515 15743444 1 1 3.9e-07 2.2e-06 1.3e-01 90 C12orf60
102 12 20151739 21604108 1 1 7.5e-08 2.4e-09 9.9e-06 45 SLCO1C1
103 12 27616589 29042392 1 1 9.1e-14 4.1e-11 3.7e-01 98 RP11-967K21.1
104 12 30084002 31526510 1 1 1.2e-13 4.9e-14 1.0e+00 100 IPO8
105 12 46077695 47465082 1 1 9.2e-08 3.9e-10 1.1e-03 73 SLC38A2
106 12 55633142 57452308 10 1 7.3e-09 3.9e-08 8.7e-01 100 RP11-977G19.11
107 12 64519806 66337026 2 1 1.4e-11 3.4e-20 7.4e-24 -20 LEMD3
108 12 93165619 94589220 1 1 8.7e-11 2.9e-24 7.8e-16 37 MRPL42
109 12 101575652 103101412 1 1 3.9e-08 2.7e-10 1.7e-08 20 DRAM1
110 13 49375072 51390447 4 7 3.9e-18 4.2e-18 1.0e+00 100 DLEU2 EBPL
111 13 77787826 79188028 1 1 9.2e-08 1.5e-07 8.3e-02 89 EDNRB
112 14 72734342 74120838 1 1 2.5e-07 1.1e-07 8.1e-03 75 RP11-109N23.6
113 14 92286262 93847625 1 1 3.6e-16 3.8e-17 1.0e+00 100 RIN3
114 14 102288663 103675360 1 1 2.6e-08 7.6e-07 6.8e-01 99 ANKRD9
115 15 39530508 41012695 1 1 1.1e-09 4.4e-08 2.7e-06 27 EIF2AK4
116 15 50649361 52091785 1 1 7.7e-08 1.5e-09 3.2e-03 76 TNFAIP8L3
117 15 66797492 68492262 2 1 4.6e-09 1.3e-10 7.1e-04 72 AAGAB
118 15 71418503 73087366 1 1 4.1e-11 2.2e-09 8.6e-01 100 MYO9A
119 15 73524629 78022087 12 5 7.5e-21 6.9e-27 8.4e-18 36 CLK3 LOXL1-AS1 MAN2C1 RCN2
120 15 78135979 79537269 1 1 2.4e-07 3.9e-08 6.0e-02 88 PSMA4
121 15 83167559 85883064 9 4 1.5e-12 8.5e-20 2.3e-03 89 AC103965.1 RP11-382A20.2
122 15 99816860 101209341 1 1 3.0e-08 4.4e-14 1.3e-11 20 CTD-3076O17.1
123 16 86671 1488646 3 1 3.6e-08 5.8e-08 1.0e+00 100 NARFL
124 16 2510603 5510848 10 3 1.2e-15 3.9e-14 3.9e-03 85 CLUAP1 ZNF213 ZNF500
125 16 13697975 15369019 2 1 2.8e-10 9.0e-09 6.1e-06 38 NPIPA2
126 16 29580611 31892919 12 2 3.7e-14 2.3e-12 1.0e+00 100 MIR4519 TBX6
127 16 68523336 71093625 14 10 4.7e-16 2.2e-25 NaN NaN COG4 CYB5B NFAT5 NOB1 PDXDC2P TMED6 WWP2
128 16 80779331 82901701 2 5 1.7e-08 1.2e-07 1.3e-77 -1140 CMIP MPHOSPH6
129 16 88030355 90172696 2 2 2.8e-10 1.9e-08 2.1e-05 43 CHMP1A SNAI3-AS1
130 17 970413 2420934 2 1 8.3e-08 5.6e-07 7.8e-01 100 SERPINF1
131 17 6644945 8041014 1 1 3.7e-07 3.7e-07 1.0e+00 100 RP11-104H15.8
132 17 26888725 29126951 8 1 5.0e-10 2.7e-09 2.3e-01 96 ANKRD13B
133 17 36211659 37644854 2 1 1.7e-08 1.6e-07 1.3e-05 30 PIP4K2B
134 17 41946180 47718188 44 8 5.9e-42 5.6e-33 1.0e+00 100 ARL17B COPZ2 HOXB4 KANSL1 LRRC37A LRRC37A2 PLCD3
135 17 60821100 64251733 24 14 9.3e-31 3.9e-28 NaN NaN AXIN2 CCDC47 CD79B CYB561 DDX42 hsa-mir-6080 MILR1 PLEKHM1P RP11-160O5.1 SMARCD2 SMURF2
136 17 78665405 80866427 7 3 6.4e-15 1.8e-12 1.0e+00 100 DCXR MYADML2 RP11-1055B8.4
137 18 69836 907710 1 1 2.7e-07 3.0e-06 5.4e-03 64 USP14
138 18 59159599 60668346 1 1 2.1e-09 1.5e-05 7.7e-01 100 KIAA1468
139 19 3309021 4732167 1 1 1.1e-07 1.0e-09 6.2e-04 69 PIAS4
140 19 10068513 11459260 1 1 5.8e-09 2.1e-08 7.5e-02 90 ILF3-AS1
141 19 40403029 43637183 4 2 1.9e-11 2.1e-11 1.0e+00 100 CXCL17 SHKBP1
142 19 45496303 46981943 2 2 8.5e-09 4.3e-09 4.6e-03 77 DMPK SNRPD2
143 20 9925555 11347455 1 1 2.3e-09 5.2e-09 5.7e-03 78 JAG1
144 20 31382860 35226873 10 4 6.0e-10 5.4e-11 7.8e-03 84 E2F1 GDF5 GSS TP53INP2
145 20 43812046 46516716 2 2 2.0e-09 8.4e-16 5.4e-10 40 EYA2 ZSWIM1
146 20 46551079 48603940 7 5 6.3e-22 7.2e-24 1.0e+00 100 ARFGEF2 CSE1L ZFAS1
147 20 61522825 62912463 11 2 4.4e-18 4.3e-16 1.0e+00 100 LIME1 ZGPAT
148 22 29707908 31360592 2 2 1.4e-09 3.0e-13 2.3e-07 50 CTA-85E5.10 OSM
149 22 42563308 44107669 1 1 3.7e-07 6.2e-06 4.4e-01 97 PACSIN2

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Crohns Disease (2017) 1.5 10 6 18.2 -0.68 1.4e-02 ADCY3 DNAJC27 LIME1 MUC1 NDST2 RP11-268J15.5 RP11-443B20.1 ZBTB38 ZGPAT ZSWIM1
Irritable Bowel Disease (IBD) 1.6 11 6 18.2 -0.97 2.3e-08 ADCY3 CTSS CXCR2 DNAJC27 LIME1 MUC1 NCOA1 RP11-316M1.12 RP11-443B20.1 SETDB1 ZGPAT
Ulcerative Colitis (UC) 1.5 3 1 3.0 0.00 1.0e+00 LIME1 MUC1 RNF123
Major Depression (MDD) 1.2 1 0 0.0 0.00 1.0e+00 PTCH1
Reaction Time 1.6 6 2 6.1 0.53 2.8e-01 ADCY3 CSE1L KANSL1 LRRC37A2 PIAS4 TMEM180
Verbal and Numeric Reasoning (VNR) 1.8 17 9 27.3 -0.68 1.4e-03 ADCY3 ARFGEF2 ARL17B C1QTNF4 CENPW CSE1L DCAF16 LRRC37A MTCH2 PPA2 RNF123 U91328.21 UBXN2A WWP2 Y_RNA ZFAS1 ZMAT2
Breast Cancer 1.8 13 11 33.3 0.47 6.4e-02 ADCY3 DNAJC27 HIST2H2AA3 LRRC37A LRRC37A2 MUC1 RIN3 RP11-196G18.24 RP11-443B20.1 RP11-73O6.3 SYNE1 ZBTB38 ZSWIM1
Ovarian Cancer 1.2 3 1 3.0 0.00 1.0e+00 HOXB4 LRRC37A LRRC37A2
Prostate Cancer 1.5 3 1 3.0 0.00 1.0e+00 LIME1 MDM4 TMEM180
Bipolar Disorder 1.9 1 0 0.0 0.00 1.0e+00 RP5-966M1.6
Body Mass Index (BMI) (2010) 1.9 6 4 12.1 0.95 6.2e-05 ADCY3 C1QTNF4 DNAJC27 MTCH2 RP11-443B20.1 Y_RNA
Coronary Artery Disease (CAD) 1.5 1 1 3.0 0.00 1.0e+00 ICA1L
Crohns Disease (2012) 1.5 3 2 6.1 0.00 1.0e+00 ADCY3 LIME1 ZGPAT
HDL Cholesterol 1.6 5 4 12.1 -0.97 1.7e-03 C1QTNF4 DDB2 MTCH2 Y_RNA ZSWIM1
LDL Cholesterol 1.2 2 1 3.0 0.00 1.0e+00 CACFD1 ICA1L
Lupus 1.1 1 0 0.0 0.00 1.0e+00 ZNF76
Neuroticism 1.4 3 1 3.0 0.00 1.0e+00 LRRC37A LRRC37A2 MTCH2
Primary Biliary Cirrhosis 1.3 1 0 0.0 0.00 1.0e+00 LRRC37A
Rheumatoid Arthritis 1.1 1 0 0.0 0.00 1.0e+00 CDK6
Schizophrenia 1.1 3 1 3.0 0.50 3.9e-01 AC103965.1 CTSS RP11-179B2.2
Ulcerative Colitis 1.5 1 1 3.0 0.00 1.0e+00 LIME1
Blood Eosinophil Count 1.4 45 30 90.9 0.26 6.6e-02 AAGAB AC103965.1 ADCY3 AHI1 ARL17B CACFD1 CDK6 CTC-228N24.3 CTSS CXCL17 DLEU2 EBPL FAM136A FAM26F GNA12 ICA1L KANSL1 KIAA1614 LRRC37A LRRC37A2 MRGPRF NARFL NOA1 NOB1 PACSIN1 PDXDC2P RAB43 RCN2 RIN3 RP11-109N23.6 RP11-316M1.12 RP11-425D10.10 RP11-443B20.1 RP11-73O6.3 RP5-966M1.6 RPL10A SEPT2 SETDB1 SLC38A2 TBX6 TRIM63 WAC-AS1 WWP2 ZNF169 ZNF76
Blood Platelet Count 1.3 56 40 121.2 0.39 1.9e-03 AC103965.1 ANKRD13B ANKRD9 AP000580.1 BOK C1QTNF4 C6orf106 CACFD1 CDK6 CEP120 CTSS CXCR2 DCAF16 DDX42 DDX6 DMPK E2F1 FAM136A FER GNA12 HSD17B3 ICA1L KIAA1614 LIME1 LRRC37A MAN2C1 MIR4519 MTCH2 MUC1 NARFL NOA1 OSM OTUD4 PACSIN1 PACSIN2 PDE12 PNKD RAPSN RIN3 RP11-109N23.6 RP11-316M1.12 RP11-425D10.10 RP5-966M1.6 SCMH1 SETDB1 SIK3 SLC38A2 SMARCD2 TBX6 TMEM180 TRIM63 Y_RNA ZCCHC24 ZGPAT ZHX2 ZNF500
Blood Red Count 1.7 56 41 124.2 0.24 6.4e-02 AC103965.1 ANKRD13B AOC1 ARL17B CACFD1 CCS CD79B CENPW CSE1L CTD-3074O7.12 CXCR2 DARS DCXR DDX42 DPP3 E2F1 EIF2AK4 FAM136A FKBP1B GPR126 HOXB4 KANSL1 KCNK7 LIME1 LRRC37A LRRC37A2 MAN2C1 MIR4519 MST1P2 MTCH2 MUC1 MYADML2 MYO9A NFAT5 NOB1 NOV PIAS4 PSMB4 RAB24 RAD9A RASA2 RCN2 RP11-109N23.6 RP11-435O5.5 RP11-73O6.3 RP11-977G19.11 RP5-966M1.6 SEPT2 SHKBP1 SMURF2 SNAI3-AS1 TBX6 WWP2 ZBTB38 ZGPAT ZSWIM1
Blood White Count 1.6 53 33 100.0 0.64 3.1e-08 AC007566.10 ADCY3 AHI1 ANKRD13B C1QTNF4 CACFD1 CCDC126 CCDC47 CDK6 CENPW CEP120 CTB-36H16.2 CXCL17 CXCR2 DCAF16 DDX42 DLG5 EBPL FER GNA12 HOXB4 HSD17B3 KIAA1614 LIME1 LRRC37A MAN2C1 MTCH2 NCOA1 NOA1 NOB1 PACSIN1 PNKD RAPSN RCN2 RIN3 RP11-1055B8.4 RP11-435O5.5 RP11-443B20.1 RP11-73O6.3 SCMH1 SIK3 SMARCD2 TMEM180 TP53I3 TPCN2 TULP4 UBXN2A WAC-AS1 Y_RNA ZGPAT ZHX2 ZNF169 ZNF76
Heel T-Score 2.7 84 64 193.9 0.14 1.7e-01 AAGAB AC007566.10 AC103965.1 ADCY3 ANAPC10 ANKRD13B ANP32E AP000580.1 ARL17B AXIN2 CACFD1 CDK6 CEP120 CHMP1A COPZ2 CRIPAK CTA-85E5.10 CTB-36H16.2 CTSS CYB5B CYBRD1 DCAF16 DCXR DDB2 DDX42 DDX6 DIRAS3 DLEU2 DLG1 E2F1 EBPL EPB41L2 EYA2 FHL3 GDF5 GNA12 GPR126 GSDMC HIST2H2AA3 IPO8 JAG1 JMJD4 KANSL1 KIAA1614 LIME1 LRRC37A LRRC37A2 MRGPRF MUC1 NDST2 NOA1 NOP58 NOV OSM PDE12 PIP4K2B PLCD3 PLEKHM1P RAPSN RASA2 ROM1 RP11-104H15.8 RP11-196G18.22 RP11-196G18.24 RP11-435O5.4 RP11-435O5.5 RP11-73O6.3 RP11-967K21.1 RP5-966M1.6 RPL10A RPS20 RRP15 SCMH1 SMARCD2 SNAI3-AS1 SYNE1 TBX6 TNFAIP8L3 TPCN2 TULP4 ZBTB38 ZCCHC24 ZNF169 ZNF76
BMI 2.8 57 35 106.1 0.68 3.8e-10 AAGAB AC092667.2 ACHE ADCY3 ANKRD13B ARFGEF2 C1QTNF4 CCDC171 CCDC47 CCS CEP120 CMIP COG4 COPZ2 CXCL17 CXCR2 CYB5B DCAF16 DDB2 DDX42 DLG1 DNAJC27 EIF2AK4 GPR126 HOXB4 LIME1 LOXL1-AS1 MFSD10 MST1P2 MTCH2 MYO9A NCOA1 NFAT5 NOB1 NOP58 NUDC OTUD4 PACSIN1 PDXDC2P PIAS4 PIGF PSMB4 RNF123 RP11-160O5.1 RP11-179B2.2 RP11-443B20.1 RP11-538P18.2 RP11-73O6.3 RP5-966M1.6 RPL10A SAR1B SMARCD2 TBX6 TMED6 WWP2 Y_RNA ZFAS1
Height 10.3 224 210 636.4 -0.90 2.2e-96 AAGAB AC007566.10 AC103965.1 ACHE ACPL2 ADCY3 AHI1 ANAPC10 ANKRD13B ANKRD9 ANP32E AOC1 AP000580.1 ARFGEF2 ARL17B AXIN2 BCKDHB BOK BRAF C10orf11 C12orf60 C1QTNF4 C2orf54 C6orf106 C9orf3 CACFD1 CAMLG CCDC126 CCDC47 CCS CD79B CDK6 CDO1 CENPO CENPW CEP120 CHMP1A CLK3 CLUAP1 CMIP COG4 COPZ2 CRIPAK CSE1L CTA-85E5.10 CTC-228N24.3 CTD-3074O7.12 CTD-3076O17.1 CTSS CXCL17 CXCR2 CYB561 CYB5B CYBRD1 DCAF16 DCXR DDB2 DDX42 DHDDS DIRAS3 DLEU2 DLG5 DNAJC27 DNAJC9-AS1 DPP3 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 EPB41L2 ERC1 ERCC6L2 FAM136A FAM26F FARP2 FER FHL3 FILIP1 FKBP1B GDF5 GNA12 GPR126 GSDMC GSS H1FX HIST2H2AA3 HOXB4 hsa-mir-6080 HSD17B3 ICA1L IGFBP3 ILF3-AS1 IPO8 JAG1 JMJD4 KANSL1 KCNK7 KIAA1614 KLHL7 LEMD3 LHFPL2 LIME1 LINC00471 LOXL1-AS1 LRRC37A LRRC37A2 MAN2C1 MDM4 MFSD10 MILR1 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1P2 MTCH2 MUC1 MXD3 MYADML2 MYO9A NARFL NCOA1 NDUFB2 NFAT5 NOA1 NOB1 NOP58 NOV NOX4 NPIPA2 NUDC OTUD4 PACSIN1 PACSIN2 PASK PDXDC2P PIAS4 PIGF PIP4K2B PLCD3 PLEKHA1 PLEKHM1P PNKD PPA2 PRPS1P2 PSMB4 PTCH1 QSOX2 RAB24 RAB43 RAD9A RAPSN RASA2 RBM4 RCN2 RP11-104H15.8 RP11-1055B8.4 RP11-109N23.6 RP11-160O5.1 RP11-179B2.2 RP11-196G18.22 RP11-196G18.24 RP11-268J15.5 RP11-382A20.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-443B20.1 RP11-538P18.2 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RP5-966M1.6 RPL10A RPS20 RRP15 SAR1B SCMH1 SEPT2 SERPINF1 SETDB1 SF3B2 SHKBP1 SIK3 SLC38A2 SLCO1C1 SMARCD2 SMURF2 SNAI3-AS1 SNRPD2 SUSD5 SYNE1 TBX6 TMED6 TMEM180 TNFAIP8L3 TNFSF10 TP53I3 TP53INP2 TPCN2 TRIM63 TSEN15 TULP4 UBXN2A UIMC1 USP14 WAC-AS1 WWP2 Y_RNA ZBTB38 ZC3H11B ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF169 ZNF213 ZNF500 ZNF76 ZSWIM1
Waist Hip Ratio (WHR) 1.8 35 21 63.6 0.28 9.7e-02 AAGAB AC103965.1 ADCY3 ANAPC10 BCKDHB CD79B CENPO CENPW CLUAP1 DLEU2 EBPL EYA2 GDF5 H1FX LRRC37A LRRC37A2 MUC1 MYADML2 NCOA1 NFAT5 OSM OTUD4 PIP4K2B PRPS1P2 RAB24 RAB43 RAD9A ROM1 RP11-73O6.3 SF3B2 SNRPD2 TNFAIP8L3 TPCN2 UIMC1 ZBTB38
Systolic Blood Pressure 1.8 36 27 81.8 0.14 3.7e-01 ACPL2 ADCY3 ARFGEF2 CDK6 CENPO CYBRD1 DCAF16 DDB2 DNAJC27 EFEMP1 EPB41L2 FER FHL3 GDF5 HOXB4 ICA1L JMJD4 KANSL1 LRRC37A LRRC37A2 MTCH2 NCOA1 NOV NUDT5 RIN3 RP11-1055B8.4 RP11-179B2.2 RP11-443B20.1 RP11-538P18.2 RPL10A SMURF2 Y_RNA ZFAS1 ZGPAT ZMAT2 ZNF500
Smoking Status 1.3 6 3 9.1 -0.12 7.9e-01 KANSL1 LRRC37A2 NOB1 PRPS1P2 RP5-966M1.6 TMEM180
Allergy or Eczema 1.4 10 8 24.2 0.27 4.2e-01 AAGAB AHI1 C6orf106 CXCR2 LIME1 PACSIN1 RASA2 TMEM180 ZBTB38 ZGPAT
Cardiovascular Disease 1.5 14 3 9.1 0.80 3.3e-04 AAGAB AC007566.10 CDK6 CENPO DCAF16 DDB2 DDX42 MFSD10 MXD3 RP11-1055B8.4 RP11-538P18.2 SMARCD2 ZGPAT ZSWIM1
Hypothyroidism (self reported) 1.2 6 3 9.1 0.13 7.8e-01 AHI1 FARP2 FHL3 MTCH2 PLEKHA1 SIK3
Respiratory disease 1.7 9 4 12.1 0.74 1.5e-02 AAGAB AHI1 CTD-3074O7.12 ICA1L LIME1 NOA1 ZGPAT ZNF169 ZNF76
Type 2 Diabetes (T2D) 1.7 9 3 9.1 0.67 5.0e-02 CENPW DMPK HOXB4 MAN2C1 NOB1 NUDT5 RCN2 WWP2 Y_RNA
Lung FEV1/FVC ratio 3.9 57 44 133.3 0.32 9.0e-03 ABLIM3 AC103965.1 ACHE ADCY3 ANKRD13B BOK C10orf11 C6orf106 CCDC171 CENPW CTA-85E5.10 CTC-228N24.3 DNAJC27 DNAJC9-AS1 DRAM1 EFEMP1 EIF2AK4 ERC1 FARP2 GDF5 GNA12 GPR126 GSS HIST2H2AA3 hsa-mir-6080 ICA1L INTS12 LOXL1-AS1 LRRC37A MILR1 MST1P2 NCOA1 NDST2 NOA1 NOV NUDT5 OTUD4 PDE12 PIP4K2B PLEKHA1 PLEKHM1P PPA2 PSMA4 PTCH1 RASA2 RP11-268J15.5 RP11-382A20.2 RP11-435O5.5 RP11-443B20.1 RPL10A RPS20 RRP15 SHKBP1 SMURF2 ZBTB38 ZFAS1 ZNF76
Lung FVC 5.7 132 99 300.0 -0.90 4.7e-55 AAGAB ABLIM3 AC073834.3 AC092667.2 AHI1 ANAPC10 ANGPTL1 AOC1 ARFGEF2 ARL17B BOK BRAF C10orf11 C2orf54 C9orf3 CACFD1 CCDC126 CCDC171 CD79B CENPW CEP120 CLUAP1 COG4 COPZ2 CTA-85E5.10 CTB-36H16.2 CTC-228N24.3 CTSS DARS DCAF16 DCXR DHDDS DIRAS3 DLG1 DPP3 EBPL EFEMP1 EIF2AK4 EIF4E3 ERC1 EYA2 FAM136A FAM26F GALNT12 GDF5 HMBS HOXB4 hsa-mir-6080 ICA1L INTS12 IPO8 JAG1 KANSL1 KCNK7 KIAA1614 LIME1 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 MAN2C1 MDM4 MFSD10 MILR1 MIR4519 MST1P2 MUC1 MYADML2 NDST2 NDUFB2 NFAT5 NOA1 NOB1 NOV NOX4 NPIPA2 NUDT5 OSM PACSIN2 PDE12 PLCD3 PLEKHM1P PPA2 PSMA4 PTCH1 QSOX2 RAD9A RBM4 RIN3 RNF123 ROM1 RP11-1055B8.4 RP11-160O5.1 RP11-316M1.12 RP11-382A20.2 RP11-425D10.10 RP11-435O5.5 RP11-538P18.2 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RPL10A RPS20 RRP15 SAR1B SCMH1 SEPT2 SETDB1 SF3B2 SHKBP1 SHROOM3 SLC38A2 SLCO1C1 SMURF2 SNAI3-AS1 SUSD5 TCP11L1 TP53I3 TRIM63 TULP4 UBXN2A USP14 WWP2 ZBTB38 ZC3H11B ZFAS1 ZGPAT ZMAT2 ZNF213 ZNF500 ZNF76
Neuroticism 1.7 11 6 18.2 0.49 9.1e-02 AAGAB ARL17B CENPW KANSL1 LRRC37A LRRC37A2 MIR4519 MTCH2 PRPS1P2 PTCH1 Y_RNA
Chronotype (morning person) 1.3 5 1 3.0 0.68 2.0e-01 C1QTNF4 CTSS CXCL17 CYB561 SETDB1
Hair Pigment 1.7 29 24 72.7 0.09 6.4e-01 ACPL2 ADCY3 ANP32E BRAF CHMP1A DCXR DDB2 DNAJC27 E2F1 EDNRB FAM136A FKBP1B GDF5 HIST2H2AA3 HMBS LRRC37A MRGPRF MYADML2 NOA1 NOX4 RASA2 RP11-268J15.5 RP11-73O6.3 SLC38A2 SNAI3-AS1 TP53INP2 TPCN2 ZBTB38 ZNF76
Tanning 1.2 15 13 39.4 -0.56 2.1e-02 ADCY3 CHMP1A CTSS DNAJC27 E2F1 GDF5 MTCH2 MXD3 NOX4 RP11-316M1.12 RP11-443B20.1 RP5-966M1.6 SETDB1 SNAI3-AS1 TP53INP2
Hand grip strength (left) 4.5 51 30 90.9 0.96 2.5e-35 ADCY3 AOC1 AP000580.1 ARFGEF2 AXIN2 BRAF C12orf60 C1QTNF4 CCS CD79B CHMP1A COG4 CTD-3074O7.12 CYB561 DARS DCAF16 DDX42 DLG5 DNAJC27 FER GDF5 GSS JAG1 JMJD4 KANSL1 LOXL1-AS1 LRRC37A LRRC37A2 MTCH2 NCOA1 NOB1 PIGF PIP4K2B PLCD3 PRPS1P2 RAD9A RAPSN RASA2 RP11-443B20.1 RP11-73O6.3 RP5-966M1.6 SETDB1 SLC38A2 TBX6 TMEM180 WWP2 Y_RNA ZBTB38 ZCCHC24 ZNF500 ZNF76
Number of treatments/medications taken 1.5 3 0 0.0 -0.91 8.9e-02 CCS DCAF16 PIAS4
Sensitivity / hurt feelings 1.6 5 5 15.2 -0.75 8.4e-02 ARL17B KANSL1 LRRC37A LRRC37A2 PTCH1
Frequency of depressed mood in last 2 weeks 1.5 3 1 3.0 0.00 1.0e+00 MTCH2 RP11-268J15.5 ZFAS1
Hearing difficulty/problems: Yes 1.4 2 2 6.1 0.00 1.0e+00 ABLIM3 DDX6
Relative age of first facial hair 1.7 8 4 12.1 -0.47 2.0e-01 CHMP1A KANSL1 LEMD3 LRRC37A LRRC37A2 NPIPA2 RP11-179B2.2 ZBTB38
Systolic blood pressure, automated reading 1.8 22 7 21.2 -0.45 3.0e-02 ADCY3 CDK6 CENPO DCAF16 DDB2 EFEMP1 FER FHL3 HOXB4 LRRC37A LRRC37A2 NCOA1 NOV NUDT5 PPA2 RP11-1055B8.4 RP11-538P18.2 RPL10A SMURF2 ZGPAT ZHX2 ZNF500
Medication: Metformin 1.7 3 0 0.0 0.00 1.0e+00 NUDT5 RCN2 Y_RNA
Diabetes (mother) 1.4 2 1 3.0 0.00 1.0e+00 NUDT5 SNRPD2
Pack years adult smoking proportion 2.2 3 1 3.0 0.00 1.0e+00 CYB561 PIAS4 PSMA4
Impedance of leg (right) 2.4 44 27 81.8 0.01 9.4e-01 AC103965.1 ADCY3 ANP32E AOC1 CCS CD79B CDK6 CDO1 CEP120 CRIPAK CTC-228N24.3 CTD-3074O7.12 CTD-3076O17.1 CTSS CYBRD1 DNAJC27 EDNRB GDF5 HIST2H2AA3 LOXL1-AS1 LRRC37A MRGPRF MST1P2 MUC1 NDST2 NOB1 OTUD4 PACSIN1 PASK PDXDC2P PTCH1 RAD9A RIN3 RP11-179B2.2 RP11-382A20.2 RP11-425D10.10 RP11-443B20.1 RP11-73O6.3 RP5-966M1.6 RPS20 SLC38A2 SNAI3-AS1 TBX6 TCP11L1
Leg fat-free mass (left) 5.0 100 74 224.2 0.93 2.7e-50 AC007566.10 ACPL2 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDHB BOK C12orf60 C6orf106 CCDC126 CD79B CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CYBRD1 DCAF16 DDX42 DLEU2 DLG5 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 EPB41L2 FHL3 FKBP1B GDF5 GNA12 GPR126 GSDMC GSS H1FX HIST2H2AA3 HSD17B3 ILF3-AS1 IPO8 JMJD4 KANSL1 KIAA1614 LHFPL2 LINC00471 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MUC1 MXD3 NARFL NCOA1 NOV NPIPA2 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PNKD PPA2 PRPS1P2 PTCH1 QSOX2 RAB24 RAB43 RAD9A RAPSN RASA2 RIN3 RP11-104H15.8 RP11-179B2.2 RP11-196G18.24 RP11-268J15.5 RP11-425D10.10 RP11-435O5.5 RP11-73O6.3 RP11-78I14.1 RPL10A RPS20 SCMH1 SEPT2 SLC38A2 SMARCD2 SYNE1 TBX6 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 UBXN2A UIMC1 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF500 ZNF76
Trunk fat percentage 3.0 41 30 90.9 -0.14 3.5e-01 AAGAB AC103965.1 ADCY3 ANP32E ARFGEF2 C1QTNF4 CCDC171 CENPW CTD-3076O17.1 CYB5B DARS DDB2 DLG1 DNAJC27 EFEMP1 GNA12 HIST2H2AA3 KANSL1 LIME1 LRRC37A LRRC37A2 MTCH2 NOB1 OTUD4 PACSIN1 PASK PIAS4 RAB43 RAD9A RAPSN RIN3 ROM1 RP11-196G18.24 RP11-443B20.1 RP11-78I14.1 RPL10A WWP2 Y_RNA ZBTB38 ZC3H11B ZGPAT
Hand grip strength (right) 4.5 51 29 87.9 0.96 5.0e-33 ACPL2 ADCY3 ANGPTL1 AOC1 AP000580.1 ARFGEF2 AXIN2 C1QTNF4 C6orf106 CCS CD79B COG4 CRIPAK CYB561 CYBRD1 DARS DCAF16 DDX42 DLG5 DNAJC27 GDF5 GSS HOXB4 JAG1 JMJD4 KANSL1 LOXL1-AS1 LRRC37A LRRC37A2 MAN2C1 MTCH2 NCOA1 NOB1 PACSIN1 PDXDC2P PIP4K2B PLCD3 PRPS1P2 RAD9A RASA2 RP11-443B20.1 RP11-73O6.3 RP5-966M1.6 SCMH1 TBX6 TMEM180 TP53INP2 Y_RNA ZBTB38 ZCCHC24 ZNF76
Townsend deprivation index at recruitment 1.3 1 0 0.0 0.00 1.0e+00 ICA1L
Current tobacco smoking 1.4 4 2 6.1 0.05 9.5e-01 ICA1L LIME1 MTCH2 PRPS1P2
Fed-up feelings 1.3 2 1 3.0 0.00 1.0e+00 LRRC37A LRRC37A2
Relative age voice broke 1.5 3 2 6.1 0.00 1.0e+00 LRRC37A LRRC37A2 SCMH1
Taking other prescription medications 1.3 1 0 0.0 0.00 1.0e+00 AHI1
Age when periods started (menarche) 2.0 16 10 30.3 0.68 1.4e-03 ADCY3 C1QTNF4 CENPW DNAJC27 MTCH2 NFAT5 NOB1 NOP58 NPIPA2 PDXDC2P PSMB4 RCN2 RP11-179B2.2 SAR1B WWP2 Y_RNA
Heel bone mineral density (BMD) T-score, automated (left) 1.9 13 9 27.3 -0.35 1.5e-01 CDK6 CRIPAK DDB2 DLEU2 EBPL FHL3 JAG1 MRGPRF RAPSN RP11-435O5.5 SYNE1 TPCN2 ZNF169
High blood pressure 1.5 8 6 18.2 -0.51 1.6e-01 ARFGEF2 CENPO DCAF16 DDB2 NCOA1 PIAS4 RAPSN RP11-538P18.2
Hayfever, allergic rhinitis or eczema 1.3 6 4 12.1 -0.43 3.3e-01 AHI1 C6orf106 LIME1 TMEM180 ZBTB38 ZGPAT
Diverticular disease/diverticulitis (self-reported) 1.3 1 0 0.0 0.00 1.0e+00 ICA1L
Medication: Levothyroxine sodium 1.1 1 0 0.0 0.00 1.0e+00 FARP2
Sitting height 9.0 163 143 433.3 0.92 8.4e-79 AC007566.10 AC073834.3 AC103965.1 ACPL2 ADCY3 ANAPC10 AOC1 ARFGEF2 ARL17B AXIN2 BCKDHB BOK C12orf60 C1QTNF4 C6orf106 C9orf3 CAMLG CCDC126 CCDC171 CCDC47 CD79B CDK6 CDO1 CENPW CEP120 CHMP1A CLK3 CMIP COG4 CRIPAK CSE1L CTD-3076O17.1 CXCL17 CXCR2 CYB5B CYBRD1 DCAF16 DCXR DDX42 DDX6 DHDDS DLEU2 DLG5 DMPK DNAJC27 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 EPB41L2 ERC1 ERCC6L2 EYA2 FAM136A FAM26F FHL3 FKBP1B GDF5 GNA12 GPR126 GSDMC GSS H1FX HIST2H2AA3 HOXB4 HSD17B3 ICA1L IGFBP3 ILF3-AS1 JAG1 JMJD4 KANSL1 KCNK7 KIAA1614 KLHL7 LEMD3 LHFPL2 LINC00471 LOXL1-AS1 LRRC37A LRRC37A2 MAN2C1 MPHOSPH6 MRGPRF MRPL42 MST1P2 MTCH2 MXD3 MYADML2 MYO9A NARFL NCOA1 NFAT5 NOB1 NOP58 NOV NUDC OTUD4 PACSIN1 PACSIN2 PASK PIGF PIP4K2B PLCD3 PLEKHA1 PNKD PPA2 PRPS1P2 PTCH1 QSOX2 RAB24 RAB43 RAD9A RAPSN RASA2 RP11-104H15.8 RP11-1055B8.4 RP11-179B2.2 RP11-196G18.24 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-443B20.1 RP11-538P18.2 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RP5-966M1.6 RPL10A RPS20 SAR1B SCMH1 SERPINF1 SLC38A2 SMARCD2 SNAI3-AS1 SNRPD2 SYNE1 TBX6 TMED6 TMEM180 TNFSF10 TP53I3 TP53INP2 TPCN2 TRIM63 TSEN15 TULP4 UBXN2A WAC-AS1 WWP2 Y_RNA ZBTB38 ZC3H11B ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF169 ZNF76 ZSWIM1
Chronic bronchitis/emphysema (father) 1.4 1 1 3.0 0.00 1.0e+00 PSMA4
Body mass index (BMI) 2.6 37 21 63.6 -0.71 7.6e-08 AC092667.2 ACHE ADCY3 ARFGEF2 C1QTNF4 CCDC171 CCS CEP120 COG4 COPZ2 CXCL17 CXCR2 CYB5B DARS DCAF16 DNAJC27 MST1P2 MTCH2 NCOA1 NOB1 NUDC OTUD4 PACSIN1 PDXDC2P PIAS4 PIGF RCN2 RP11-179B2.2 RP11-443B20.1 RP5-966M1.6 RPL10A SAR1B TBX6 TMED6 WWP2 Y_RNA ZFAS1
Impedance of leg (left) 2.4 47 26 78.8 0.06 6.9e-01 AC103965.1 ADCY3 AOC1 CCS CD79B CDK6 CDO1 CEP120 CHMP1A COG4 CTC-228N24.3 CTD-3074O7.12 CTD-3076O17.1 CTSS CXCR2 CYBRD1 DNAJC27 EDNRB GDF5 GPR126 GSS LOXL1-AS1 LRRC37A MRGPRF MST1P2 MUC1 NDST2 NOB1 OTUD4 PACSIN1 PASK PDXDC2P PPA2 PTCH1 RAD9A RCN2 RIN3 RP11-179B2.2 RP11-382A20.2 RP11-425D10.10 RP11-443B20.1 RP11-73O6.3 RP5-966M1.6 RPS20 SEPT2 SLC38A2 TBX6
Leg predicted mass (left) 5.0 100 74 224.2 0.93 4.4e-50 AC007566.10 ACPL2 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDHB BOK C12orf60 C6orf106 CCDC126 CD79B CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CYBRD1 DCAF16 DDX42 DLEU2 DLG5 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 EPB41L2 FHL3 FKBP1B GDF5 GNA12 GPR126 GSDMC GSS H1FX HIST2H2AA3 HSD17B3 ILF3-AS1 IPO8 JMJD4 KANSL1 KIAA1614 LHFPL2 LINC00471 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MUC1 MXD3 NARFL NCOA1 NOV NPIPA2 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PNKD PPA2 PRPS1P2 PTCH1 QSOX2 RAB24 RAB43 RAD9A RAPSN RASA2 RIN3 RP11-104H15.8 RP11-179B2.2 RP11-196G18.24 RP11-268J15.5 RP11-425D10.10 RP11-435O5.5 RP11-73O6.3 RP11-78I14.1 RPL10A RPS20 SCMH1 SEPT2 SLC38A2 SMARCD2 SYNE1 TBX6 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 UBXN2A UIMC1 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF500 ZNF76
Trunk fat mass 3.0 50 40 121.2 0.38 3.4e-03 AAGAB AC103965.1 ADCY3 ANAPC10 ANP32E BOK C1QTNF4 C6orf106 CCDC171 CDK6 CEP120 CTD-3076O17.1 CYB5B DLG1 DNAJC27 E2F1 EFEMP1 EIF2AK4 GDF5 GNA12 GPR126 GSS HIST2H2AA3 KANSL1 LIME1 LRRC37A LRRC37A2 MPHOSPH6 MTCH2 NOB1 OTUD4 PACSIN1 PIAS4 PLEKHA1 RAB43 RAD9A RASA2 RP11-179B2.2 RP11-196G18.24 RP11-443B20.1 RP11-73O6.3 RP11-78I14.1 RPL10A TBX6 TP53INP2 WWP2 Y_RNA ZBTB38 ZC3H11B ZNF500
Waist circumference 2.2 27 23 69.7 -0.15 3.9e-01 AAGAB AC092667.2 ADCY3 C1QTNF4 C6orf106 CCDC171 CDK6 CEP120 COPZ2 CYB5B DNAJC27 LIME1 MTCH2 NOB1 OTUD4 PACSIN1 PIAS4 RAD9A RP11-179B2.2 RP11-443B20.1 RP11-78I14.1 RPL10A SAR1B TBX6 WWP2 Y_RNA ZBTB38
Number of incorrect matches in round 1.6 1 1 3.0 0.00 1.0e+00 TBX6
Past tobacco smoking 1.4 5 2 6.1 0.63 1.8e-01 NOA1 NOB1 PRPS1P2 RP11-977G19.11 TMEM180
Nervous feelings 1.5 7 3 9.1 -0.81 2.6e-02 CENPW CYB5B KANSL1 LRRC37A LRRC37A2 RP5-966M1.6 TBX6
Frequency of tenseness / restlessness in last 2 weeks 1.4 5 2 6.1 -0.86 6.3e-02 ARL17B KANSL1 LRRC37A LRRC37A2 RP11-268J15.5
Hearing difficulty/problems with background noise 1.4 2 0 0.0 0.00 1.0e+00 DDX6 LRRC37A
Hair/balding pattern: Pattern 2 1.4 3 2 6.1 0.00 1.0e+00 C10orf11 LRRC37A LRRC37A2
Had other major operations 1.3 1 0 0.0 0.00 1.0e+00 PPA2
Heel bone mineral density (BMD) T-score, automated (right) 1.8 15 7 21.2 -0.41 9.1e-02 CDK6 CRIPAK DDB2 DLEU2 EBPL FHL3 MRGPRF NOA1 RAPSN RP11-435O5.5 SYNE1 TPCN2 ZBTB38 ZNF169 ZNF76
Ever unenthusiastic/disinterested for a whole week 1.2 2 0 0.0 0.00 1.0e+00 LRRC37A ZMAT2
Qualifications: None of the above 1.3 2 0 0.0 0.00 1.0e+00 PPA2 RNF123
Mouth/teeth dental problems 1.2 3 0 0.0 0.00 1.0e+00 KANSL1 LRRC37A2 MUC1
Allergy 1.4 9 6 18.2 0.35 3.1e-01 AAGAB AHI1 AP000580.1 C6orf106 CTD-3074O7.12 LIME1 TMEM180 ZBTB38 ZGPAT
Diabetes (self-reported) 1.7 3 0 0.0 0.00 1.0e+00 CLUAP1 MAN2C1 RCN2
Medication: Simvastatin 1.3 1 0 0.0 0.00 1.0e+00 DCAF16
Fluid intelligence score 1.6 7 3 9.1 0.83 6.0e-03 C1QTNF4 CSE1L DCAF16 MTCH2 PPA2 RNF123 U91328.21
Neuroticism score 1.6 7 5 15.2 -0.42 2.6e-01 ARL17B KANSL1 LRRC37A LRRC37A2 MTCH2 PTCH1 Y_RNA
Weight 3.7 76 54 163.6 0.78 5.6e-19 AAGAB AC007566.10 AC103965.1 ADCY3 ANAPC10 BCKDHB BOK C1QTNF4 C6orf106 CCDC171 CD79B CDK6 CENPW CEP120 CRIPAK CTD-3076O17.1 CYBRD1 DCAF16 DDX42 DLEU2 DNAJC27 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 EPB41L2 FKBP1B GDF5 GNA12 GPR126 GSDMC GSS H1FX HIST2H2AA3 ILF3-AS1 KANSL1 LHFPL2 LIME1 MPHOSPH6 MRGPRF MRPL42 MUC1 MXD3 NARFL NPIPA2 OTUD4 PACSIN1 PLEKHA1 PPA2 RAB43 RAD9A RASA2 RP11-104H15.8 RP11-179B2.2 RP11-196G18.24 RP11-425D10.10 RP11-435O5.5 RP11-443B20.1 RP11-73O6.3 RP11-78I14.1 RPL10A RPS20 SCMH1 SEPT2 SERPINF1 SLC38A2 SYNE1 TBX6 TMEM180 TP53INP2 TSEN15 ZBTB38 ZC3H11B ZCCHC24 ZNF500
Impedance of arm (right) 2.3 40 30 90.9 0.24 1.2e-01 AAGAB AC103965.1 ACHE ANP32E AOC1 ARL17B CD79B CENPW CEP120 CRIPAK CTD-3076O17.1 CYBRD1 EFEMP1 FER GPR126 HIST2H2AA3 KANSL1 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 MRPL42 MST1P2 MUC1 PACSIN1 PASK RIN3 ROM1 RP11-179B2.2 RP11-196G18.22 RP11-196G18.24 RP11-73O6.3 RP5-966M1.6 RPL10A RPS20 SAR1B SCMH1 SLC38A2 TBX6 ZC3H11B
Arm fat percentage (right) 3.4 40 25 75.8 -0.73 3.7e-09 AAGAB ADCY3 ANKRD13B ARFGEF2 C1QTNF4 CCDC171 CCS CD79B CENPW COPZ2 CTD-3074O7.12 CYB5B DCAF16 DDB2 DLG1 DNAJC27 DPP3 HIST2H2AA3 ICA1L KANSL1 LIME1 MTCH2 NCOA1 NFAT5 NOB1 NOP58 NOV PDXDC2P PIAS4 PIGF RAPSN RP11-196G18.24 RP11-443B20.1 RP11-78I14.1 SAR1B TBX6 WWP2 Y_RNA ZFAS1 ZNF76
Trunk fat-free mass 6.9 128 104 315.2 0.93 1.7e-66 AC007566.10 ACPL2 ADCY3 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDHB BOK C12orf60 C1QTNF4 C6orf106 C9orf3 CCDC126 CCDC47 CD79B CDK6 CENPO CENPW CEP120 CHMP1A COG4 CRIPAK CSE1L CXCR2 CYBRD1 DCAF16 DDX42 DDX6 DHDDS DLEU2 DLG1 DLG5 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 EPB41L2 FAM136A FHL3 FKBP1B GDF5 GNA12 GPR126 GSDMC GSS H1FX HSD17B3 ILF3-AS1 IPO8 JMJD4 KCNK7 KIAA1614 LEMD3 LHFPL2 LINC00471 LOXL1-AS1 MAN2C1 MPHOSPH6 MRGPRF MRPL42 MST1P2 MTCH2 MUC1 MXD3 MYO9A NARFL NCOA1 NDUFB2 NOA1 NOV NOX4 NPIPA2 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PNKD PPA2 PRPS1P2 PTCH1 QSOX2 RAB24 RAB43 RAD9A RAPSN RASA2 RIN3 RP11-104H15.8 RP11-179B2.2 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RPL10A RPS20 SAR1B SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 SNAI3-AS1 SYNE1 TBX6 TMEM180 TNFSF10 TP53I3 TP53INP2 TPCN2 TRIM63 TSEN15 UBXN2A UIMC1 Y_RNA ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF213 ZNF500 ZNF76
Hip circumference 3.1 54 41 124.2 0.49 4.8e-05 AC103965.1 ADCY3 ANAPC10 BOK C1QTNF4 C6orf106 CCDC171 CD79B CDK6 CEP120 CYBRD1 DCXR DLEU2 DNAJC27 E2F1 EFEMP1 EIF2AK4 EPB41L2 EYA2 GDF5 GNA12 GPR126 GSS H1FX HIST2H2AA3 LIME1 MPHOSPH6 MTCH2 NARFL NOB1 OTUD4 PACSIN1 PLEKHA1 RAB43 RAD9A RASA2 RP11-104H15.8 RP11-179B2.2 RP11-196G18.24 RP11-425D10.10 RP11-435O5.5 RP11-443B20.1 RP11-73O6.3 RP11-78I14.1 RPL10A RPS20 SLC38A2 TBX6 TP53INP2 TPCN2 WWP2 Y_RNA ZBTB38 ZC3H11B
Father's age at death 1.2 1 1 3.0 0.00 1.0e+00 PSMA4
Worrier / anxious feelings 1.4 6 3 9.1 -0.49 3.2e-01 KANSL1 LRRC37A LRRC37A2 PTCH1 RP5-966M1.6 TMEM180
Frequency of tiredness / lethargy in last 2 weeks 1.5 2 0 0.0 0.00 1.0e+00 MTCH2 ZFAS1
Hair/balding pattern: Pattern 3 1.8 5 3 9.1 0.68 2.1e-01 ARL17B CENPW KANSL1 LRRC37A LRRC37A2
Number of live births 1.0 1 0 0.0 0.00 1.0e+00 LRRC37A
Forced expiratory volume in 1-second (FEV1) 9.8 207 152 460.6 0.98 1.5e-183 ABLIM3 AC073834.3 AC092667.2 AC103965.1 ACHE ADCY3 AHI1 ANAPC10 ANGPTL1 ANP32E AOC1 AP000580.1 ARFGEF2 ARL17B AXIN2 BCKDHB BOK BRAF C10orf11 C12orf60 C1QTNF4 C6orf106 CACFD1 CAMLG CCDC126 CCDC171 CCS CD79B CDK6 CDO1 CENPO CENPW CEP120 CHMP1A CLK3 CLUAP1 CMIP COG4 CRIPAK CTA-85E5.10 CTB-36H16.2 CTD-3074O7.12 CTD-3076O17.1 CTSS CXCL17 CXCR2 CYB561 CYB5B CYBRD1 DARS DCAF16 DCXR DDB2 DDX42 DHDDS DIRAS3 DLEU2 DLG1 DLG5 DNAJC27 DNAJC9-AS1 DPP3 EBPL EFEMP1 EIF2AK4 ERCC6L2 EYA2 FAM136A FAM26F FAM35A FER FHL3 FILIP1 FKBP1B GALNT12 GDF5 GSDMC GSS H1FX HIST2H2AA3 HMBS HOXB4 hsa-mir-6080 HSD17B3 IGFBP3 ILF3-AS1 INTS12 IPO8 JAG1 JMJD4 KANSL1 KIAA1468 KIAA1614 LEMD3 LHFPL2 LIME1 LINC00471 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 MAN2C1 MDM4 MFSD10 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1P2 MTCH2 MUC1 MXD3 MYADML2 MYO9A NARFL NCOA1 NDST2 NFAT5 NOA1 NOB1 NOV NOX4 NPIPA2 NUDC NUDT5 OSM OTUD4 PACSIN1 PDE12 PDXDC2P PIAS4 PLCD3 PLEKHM1P PNKD PPA2 PRPS1P2 PSMA4 PSMB4 PTCH1 QSOX2 RAB24 RAB43 RAD9A RAPSN RASA2 RBM4 RCN2 RIN3 RNF123 ROM1 RP11-1055B8.4 RP11-179B2.2 RP11-196G18.24 RP11-316M1.12 RP11-382A20.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-443B20.1 RP11-538P18.2 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RP5-966M1.6 RPL10A RPS20 SAR1B SCMH1 SERPINF1 SETDB1 SF3B2 SLC38A2 SLCO1C1 SMARCD2 SMURF2 SNAI3-AS1 SUSD5 SYNE1 TCP11L1 TMED6 TMEM180 TNFAIP8L3 TNFSF10 TP53I3 TP53INP2 TPCN2 TRIM63 TSEN15 TULP4 U91328.21 UBXN2A WAC-AS1 WWP2 Y_RNA ZBTB38 ZC3H11B ZCCHC24 ZFAS1 ZGPAT ZHX2 ZMAT2 ZNF169 ZNF213 ZNF500 ZNF76 ZSWIM1
Pulse rate 1.3 4 1 3.0 -0.11 8.6e-01 ACHE CEP120 ROM1 ZBTB38
Happiness 1.2 1 1 3.0 0.00 1.0e+00 ZFAS1
Qualifications: A levels/AS levels or equivalent 1.4 2 1 3.0 0.00 1.0e+00 LRRC37A RNF123
Mouth/teeth dental problems: Dentures 1.4 4 1 3.0 -0.99 5.6e-03 ADCY3 MUC1 PSMA4 RP11-1055B8.4
Asthma 1.7 7 3 9.1 -0.76 2.9e-02 AAGAB AHI1 CCS CTD-3074O7.12 U91328.21 ZGPAT ZNF76
Medication: Ibuprofen (e.g. Nurofen) 1.1 2 0 0.0 0.00 1.0e+00 LRRC37A U91328.21
Medication: Cholesterol lowering 1.3 1 0 0.0 0.00 1.0e+00 DCAF16
Lung cancer (father) 1.5 1 1 3.0 0.00 1.0e+00 PSMA4
Forced expiratory volume in 1-second (FEV1), Best measure 9.4 181 122 369.7 0.98 1.9e-154 ABLIM3 AC073834.3 AC092667.2 AC103965.1 ACHE ADCY3 AHI1 ANAPC10 ANGPTL1 AOC1 ARFGEF2 ARL17B AXIN2 BCKDHB BOK BRAF C10orf11 C12orf60 C1QTNF4 C6orf106 CACFD1 CAMLG CCDC126 CCDC171 CCS CD79B CDK6 CDO1 CENPW CEP120 CLK3 CLUAP1 CMIP COG4 CRIPAK CTA-85E5.10 CTB-36H16.2 CTD-3074O7.12 CTD-3076O17.1 CTSS CXCL17 CXCR2 CYB561 CYB5B CYBRD1 DARS DCAF16 DCXR DDB2 DDX42 DHDDS DIRAS3 DLEU2 DLG1 DLG5 DNAJC27 DNAJC9-AS1 DPP3 EBPL EFEMP1 ERCC6L2 FAM136A FAM26F FER FILIP1 GALNT12 GDF5 GSDMC GSS H1FX HOXB4 hsa-mir-6080 HSD17B3 ILF3-AS1 INTS12 IPO8 JAG1 JMJD4 KANSL1 KIAA1468 KIAA1614 LEMD3 LHFPL2 LIME1 LINC00471 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 MAN2C1 MDM4 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1P2 MTCH2 MXD3 MYADML2 MYO9A NCOA1 NDST2 NFAT5 NOA1 NOB1 NPIPA2 NUDC NUDT5 OSM OTUD4 PACSIN1 PDE12 PDXDC2P PIAS4 PLCD3 PLEKHM1P PNKD PPA2 PRPS1P2 PSMA4 PSMB4 QSOX2 RAB24 RAD9A RAPSN RASA2 RBM4 RIN3 RNF123 ROM1 RP11-1055B8.4 RP11-179B2.2 RP11-196G18.24 RP11-382A20.2 RP11-425D10.10 RP11-443B20.1 RP11-538P18.2 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RP5-966M1.6 RPL10A RPS20 SAR1B SCMH1 SERPINF1 SETDB1 SHKBP1 SMARCD2 SMURF2 SNAI3-AS1 SYNE1 TCP11L1 TMED6 TMEM180 TNFAIP8L3 TNFSF10 TP53I3 TP53INP2 TRIM63 TSEN15 TULP4 U91328.21 UBXN2A WAC-AS1 WWP2 Y_RNA ZBTB38 ZC3H11B ZCCHC24 ZFAS1 ZGPAT ZHX2 ZMAT2 ZNF169 ZNF213 ZNF500 ZNF76 ZSWIM1
Impedance of arm (left) 2.3 39 28 84.8 0.28 6.1e-02 AC103965.1 ACHE ANP32E AOC1 ARL17B CD79B CENPW CEP120 CTD-3076O17.1 DLG1 EFEMP1 FER GNA12 GPR126 HIST2H2AA3 KANSL1 LOXL1-AS1 LRRC37A LRRC37A2 MRPL42 MST1P2 MUC1 PACSIN1 PASK RIN3 ROM1 RP11-179B2.2 RP11-196G18.22 RP11-196G18.24 RP11-73O6.3 RP5-966M1.6 RPL10A RPS20 SAR1B SCMH1 SHKBP1 SLC38A2 TBX6 ZC3H11B
Arm fat mass (right) 2.5 33 22 66.7 -0.12 4.6e-01 AAGAB AC092667.2 ADCY3 C1QTNF4 CCDC171 CCS CDK6 CEP120 COPZ2 CYB5B DNAJC27 HIST2H2AA3 KANSL1 LIME1 MTCH2 NOB1 OTUD4 PACSIN1 PDXDC2P PIAS4 RAB43 RASA2 RP11-179B2.2 RP11-196G18.24 RP11-443B20.1 RP11-73O6.3 RP11-78I14.1 RPL10A TBX6 TP53INP2 WWP2 Y_RNA ZBTB38
Trunk predicted mass 6.9 129 103 312.1 0.93 9.5e-67 AC007566.10 ACPL2 ADCY3 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDHB BOK C12orf60 C1QTNF4 C6orf106 C9orf3 CCDC126 CCDC47 CD79B CDK6 CENPO CENPW CEP120 CHMP1A COG4 CRIPAK CSE1L CXCR2 CYBRD1 DCAF16 DDX42 DDX6 DHDDS DLEU2 DLG1 DLG5 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 EPB41L2 FAM136A FHL3 FKBP1B GDF5 GNA12 GPR126 GSDMC GSS H1FX HSD17B3 ILF3-AS1 IPO8 JMJD4 KCNK7 KIAA1614 LEMD3 LHFPL2 LINC00471 LOXL1-AS1 MAN2C1 MPHOSPH6 MRGPRF MRPL42 MST1P2 MTCH2 MUC1 MXD3 MYO9A NARFL NCOA1 NDUFB2 NOA1 NOV NOX4 NPIPA2 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PNKD PPA2 PRPS1P2 PTCH1 QSOX2 RAB24 RAB43 RAD9A RAPSN RASA2 RIN3 RP11-104H15.8 RP11-179B2.2 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RPL10A RPS20 SAR1B SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 SNAI3-AS1 SYNE1 TBX6 TMEM180 TNFSF10 TP53I3 TP53INP2 TPCN2 TRIM63 TSEN15 UBXN2A UIMC1 WAC-AS1 Y_RNA ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF213 ZNF500 ZNF76
Standing height 10.3 205 183 554.5 0.93 5.8e-104 AAGAB AC007566.10 AC103965.1 ACHE ACPL2 ADCY3 ANAPC10 ANKRD13B ANKRD9 ANP32E AOC1 AP000580.1 ARFGEF2 ARL17B AXIN2 BCKDHB BOK BRAF C12orf60 C1QTNF4 C6orf106 C9orf3 CAMLG CCDC126 CCDC47 CCS CD79B CDK6 CDO1 CENPO CENPW CEP120 CHMP1A CLK3 CMIP COG4 COPZ2 CRIPAK CSE1L CTD-3074O7.12 CTD-3076O17.1 CXCL17 CXCR2 CYB561 CYB5B CYBRD1 DCAF16 DDB2 DDX42 DDX6 DHDDS DLEU2 DLG5 DMPK DNAJC27 DPP3 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 EPB41L2 ERC1 ERCC6L2 FAM136A FAM26F FAM35A FARP2 FER FHL3 FILIP1 FKBP1B GDF5 GNA12 GPR126 GSDMC GSS H1FX HIST2H2AA3 HMBS HOXB4 hsa-mir-6080 HSD17B3 IGFBP3 ILF3-AS1 IPO8 JAG1 JMJD4 KANSL1 KCNK7 KIAA1468 KIAA1614 KLHL7 LEMD3 LHFPL2 LINC00471 LOXL1-AS1 LRRC37A LRRC37A2 MAN2C1 MFSD10 MILR1 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1P2 MTCH2 MXD3 MYADML2 MYO9A NARFL NCOA1 NDUFB2 NFAT5 NOA1 NOB1 NOP58 NOV NOX4 NPIPA2 NUDC OTUD4 PACSIN1 PACSIN2 PASK PDXDC2P PIAS4 PIGF PIP4K2B PLCD3 PLEKHA1 PLEKHM1P PNKD PPA2 PRPS1P2 PSMB4 PTCH1 QSOX2 RAB24 RAB43 RAD9A RAPSN RASA2 RCN2 RP11-104H15.8 RP11-1055B8.4 RP11-160O5.1 RP11-179B2.2 RP11-196G18.22 RP11-196G18.24 RP11-268J15.5 RP11-382A20.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-443B20.1 RP11-538P18.2 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-977G19.11 RP5-966M1.6 RPL10A RPS20 RRP15 SAR1B SCMH1 SEPT2 SERPINF1 SLC38A2 SLCO1C1 SMARCD2 SMURF2 SNAI3-AS1 SUSD5 SYNE1 TBX6 TMED6 TMEM180 TNFAIP8L3 TNFSF10 TP53I3 TP53INP2 TPCN2 TRIM63 TSEN15 TULP4 UBXN2A UIMC1 WAC-AS1 WWP2 Y_RNA ZBTB38 ZC3H11B ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF169 ZNF213 ZNF500 ZNF76 ZSWIM1
Tense / 'highly strung' 1.3 1 0 0.0 0.00 1.0e+00 ANP32E
Seen doctor (GP) for nerves, anxiety, tension or depression 1.6 3 1 3.0 -0.45 5.5e-01 CCS CTD-3074O7.12 U91328.21
Hair/balding pattern: Pattern 4 2.4 11 10 30.3 0.03 9.1e-01 ARL17B C10orf11 CENPW CTB-36H16.2 DLG5 FAM136A KANSL1 LRRC37A LRRC37A2 RASA2 ZBTB38
Birth weight of first child 2.4 11 7 21.2 0.97 4.0e-08 ANAPC10 ARFGEF2 DCAF16 DCXR IPO8 OTUD4 PPA2 RP11-78I14.1 RPL10A ZBTB38 ZNF76
Peak expiratory flow (PEF) 4.8 51 22 66.7 0.96 1.3e-30 ANAPC10 ARFGEF2 BOK C10orf11 C6orf106 CACFD1 CCS CD79B CTA-85E5.10 CTD-3074O7.12 DCAF16 DCXR DHDDS DLEU2 DLG1 DPP3 EFEMP1 FKBP1B GDF5 GSDMC GSS KANSL1 LRRC37A LRRC37A2 MDM4 MPHOSPH6 MRGPRF MYADML2 NOA1 NPIPA2 NUDT5 OTUD4 PIAS4 PNKD PPA2 PRPS1P2 RAD9A RBM4 RNF123 RP11-179B2.2 RP11-425D10.10 RPL10A SF3B2 SYNE1 TCP11L1 TP53INP2 TRIM63 UBXN2A Y_RNA ZHX2 ZNF76
Qualifications: O levels/GCSEs or equivalent 1.2 1 0 0.0 0.00 1.0e+00 ZNF500
Blood clot in the leg (DVT) 1.1 1 1 3.0 0.00 1.0e+00 CACFD1
Medication: Paracetamol 1.4 3 3 9.1 0.00 1.0e+00 LRRC37A LRRC37A2 U91328.21
Headache pain in last month 1.5 4 3 9.1 -0.79 2.1e-01 LRRC37A LRRC37A2 NOA1 U91328.21
Medication for cholesterol, blood pressure or diabetes 1.5 1 0 0.0 0.00 1.0e+00 DCAF16
Gout (self-reported) 1.2 2 1 3.0 0.00 1.0e+00 MUC1 WWP2
Hypothyroidism/myxoedema (self-reported) 1.2 2 1 3.0 0.00 1.0e+00 AHI1 PLEKHA1
Medication: Amlodipine 1.1 1 0 0.0 0.00 1.0e+00 DDB2
Medication: Ventolin 100micrograms inhaler 1.1 1 0 0.0 0.00 1.0e+00 AAGAB
Birth weight 2.5 18 5 15.2 0.86 2.2e-06 ANAPC10 C1QTNF4 CCDC126 CDK6 CENPW CXCL17 DCAF16 GNA12 GPR126 MTCH2 PPA2 RP11-425D10.10 RP11-435O5.5 RP11-73O6.3 SYNE1 UBXN2A Y_RNA ZNF76
Chronic bronchitis/emphysema (mother) 1.3 1 1 3.0 0.00 1.0e+00 PSMA4
Forced vital capacity (FVC), Best measure 11.5 242 208 630.3 1.00 2.8e-303 AAGAB ABLIM3 AC073834.3 AC092667.2 AC103965.1 ACHE ACPL2 ADCY3 AHI1 ANAPC10 ANGPTL1 ANKRD13B ANKRD9 ANP32E AOC1 AP000580.1 ARFGEF2 ARL17B AXIN2 BCKDHB BOK BRAF C10orf11 C12orf60 C1QTNF4 C2orf54 C6orf106 C9orf3 CACFD1 CAMLG CCDC126 CCDC171 CCDC47 CCS CD79B CDK6 CDO1 CENPW CEP120 CHMP1A CLK3 CLUAP1 CMIP COG4 CRIPAK CSE1L CTA-85E5.10 CTB-36H16.2 CTC-228N24.3 CTD-3074O7.12 CTD-3076O17.1 CTSS CXCL17 CXCR2 CYB561 CYB5B CYBRD1 DARS DCAF16 DCXR DDB2 DDX42 DDX6 DHDDS DIRAS3 DLEU2 DLG1 DLG5 DMPK DNAJC27 DNAJC9-AS1 DPP3 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 EPB41L2 ERC1 ERCC6L2 EYA2 FAM136A FAM26F FARP2 FER FHL3 FILIP1 FKBP1B GALNT12 GDF5 GNA12 GPR126 GSDMC GSS H1FX HIST2H2AA3 HMBS HOXB4 hsa-mir-6080 HSD17B3 ICA1L ILF3-AS1 INTS12 IPO8 JAG1 JMJD4 KANSL1 KCNK7 KIAA1468 KIAA1614 LEMD3 LHFPL2 LIME1 LINC00471 LOXL1-AS1 LRPAP1 LRRC37A LRRC37A2 MAN2C1 MDM4 MILR1 MIR4519 MPHOSPH6 MRGPRF MRPL42 MST1P2 MTCH2 MUC1 MXD3 MYADML2 MYO9A NARFL NCOA1 NDST2 NDUFB2 NFAT5 NOA1 NOB1 NOP58 NOV NOX4 NPIPA2 NUDC NUDT5 OSM OTUD4 PACSIN1 PACSIN2 PASK PDE12 PDXDC2P PIAS4 PIGF PIP4K2B PLCD3 PLEKHA1 PLEKHM1P PNKD PPA2 PSMA4 PSMB4 PTCH1 QSOX2 RAB24 RAD9A RAPSN RASA2 RBM4 RCN2 RIN3 RNF123 ROM1 RP11-104H15.8 RP11-1055B8.4 RP11-109N23.6 RP11-160O5.1 RP11-179B2.2 RP11-196G18.22 RP11-196G18.24 RP11-268J15.5 RP11-316M1.12 RP11-382A20.2 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-443B20.1 RP11-538P18.2 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP11-967K21.1 RP11-977G19.11 RP5-966M1.6 RPL10A RPS20 RRP15 SAR1B SCMH1 SEPT2 SERPINF1 SETDB1 SF3B2 SHKBP1 SHROOM3 SIK3 SLCO1C1 SMARCD2 SMURF2 SNAI3-AS1 SNRPD2 SUSD5 SYNE1 TBX6 TCP11L1 TMED6 TMEM180 TNFAIP8L3 TNFSF10 TP53I3 TP53INP2 TRIM63 TSEN15 TULP4 U91328.21 UBXN2A UIMC1 USP14 WAC-AS1 WWP2 Y_RNA ZBTB38 ZC3H11B ZCCHC24 ZFAS1 ZGPAT ZHX2 ZMAT2 ZNF169 ZNF213 ZNF500 ZNF76 ZSWIM1
Body fat percentage 3.1 43 24 72.7 -0.50 1.4e-04 AAGAB AC073834.3 AC103965.1 ADCY3 ANKRD13B ANP32E ARFGEF2 C1QTNF4 CCDC171 CD79B CENPW COPZ2 CTD-3076O17.1 CXCL17 CYB5B DARS DCAF16 DDB2 DLG1 DNAJC27 HIST2H2AA3 HMBS KANSL1 LIME1 LRRC37A2 MTCH2 NCOA1 NOB1 NOV PIAS4 RAPSN RIN3 ROM1 RP11-196G18.24 RP11-443B20.1 RP11-78I14.1 SAR1B WWP2 Y_RNA ZBTB38 ZC3H11B ZFAS1 ZGPAT
Leg fat percentage (right) 3.3 44 28 84.8 -0.88 2.4e-17 AAGAB AC073834.3 AC103965.1 ADCY3 ANKRD13B ARFGEF2 C1QTNF4 CCDC171 CD79B CENPW COPZ2 CTC-228N24.3 CXCL17 CYB5B DARS DCAF16 DDX42 DLG1 DNAJC27 GDF5 HMBS hsa-mir-6080 HSD17B3 ICA1L LIME1 MTCH2 NCOA1 NOB1 NOV PDXDC2P PIAS4 PIGF PLEKHM1P RAPSN RIN3 RP11-435O5.5 RP11-443B20.1 SAR1B SMARCD2 SNAI3-AS1 WWP2 Y_RNA ZFAS1 ZGPAT
Arm fat-free mass (right) 5.6 103 81 245.5 0.94 8.1e-57 AC007566.10 ACPL2 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDHB BOK C12orf60 C6orf106 CCDC126 CD79B CDK6 CENPW CEP120 CHMP1A COG4 CRIPAK CXCR2 CYBRD1 DCAF16 DDX42 DDX6 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 EPB41L2 FHL3 FKBP1B GDF5 GNA12 GPR126 GSDMC GSS H1FX HSD17B3 ILF3-AS1 IPO8 JMJD4 KIAA1614 LEMD3 LHFPL2 LINC00471 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MUC1 MXD3 NARFL NCOA1 NDUFB2 NOV NPIPA2 OTUD4 PACSIN1 PLEKHA1 PNKD PPA2 PRPS1P2 PTCH1 RAB24 RAB43 RAD9A RAPSN RASA2 RIN3 RP11-104H15.8 RP11-179B2.2 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RPL10A RPS20 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 SYNE1 TBX6 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 UBXN2A UIMC1 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF76
Comparative body size at age 10 4.4 13 8 24.2 -0.88 2.4e-06 ADCY3 C1QTNF4 CENPO CMIP DMPK DNAJC27 ERCC6L2 MTCH2 NCOA1 RP11-443B20.1 U91328.21 UIMC1 Y_RNA
Number of full brothers 1.2 1 0 0.0 0.00 1.0e+00 LRRC37A2
Worry too long after embarrassment 1.6 4 0 0.0 -0.29 7.1e-01 AHI1 LRRC37A LRRC37A2 PPA2
Wheeze or whistling in the chest in last year 1.7 5 1 3.0 -0.99 1.1e-03 CCDC171 HSD17B3 LIME1 NDST2 ZGPAT
Qualifications: College or University degree 1.5 13 6 18.2 0.94 1.2e-06 DCAF16 DDX42 GDF5 KANSL1 LRRC37A LRRC37A2 MDM4 MFSD10 PPA2 RASA2 RNF123 RP11-1055B8.4 SMARCD2
Medication for pain relief, constipation, heartburn 1.4 4 2 6.1 0.53 4.7e-01 LRRC37A LRRC37A2 PLCD3 U91328.21
Medication: Blood pressure 1.5 2 1 3.0 0.00 1.0e+00 DCAF16 DDB2
Medication: Allopurinol 1.2 2 1 3.0 0.00 1.0e+00 MUC1 WWP2
Mean time to correctly identify matches 1.5 5 2 6.1 -0.55 3.3e-01 ARFGEF2 CSE1L KANSL1 LRRC37A2 PIAS4
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.6 1 0 0.0 0.00 1.0e+00 LRRC37A2
Whole body fat mass 2.7 44 32 97.0 0.26 6.3e-02 AAGAB AC103965.1 ADCY3 ANAPC10 ANP32E C1QTNF4 C6orf106 CCDC171 CDK6 CEP120 CTD-3076O17.1 CYB5B DLG1 DNAJC27 E2F1 EFEMP1 GNA12 GPR126 GSS HIST2H2AA3 KANSL1 LIME1 LRRC37A2 MPHOSPH6 MTCH2 NOB1 OTUD4 PACSIN1 PIAS4 RAB43 RAD9A RASA2 RP11-179B2.2 RP11-196G18.24 RP11-443B20.1 RP11-73O6.3 RP11-78I14.1 RPL10A TBX6 TP53INP2 WWP2 Y_RNA ZBTB38 ZC3H11B
Leg fat mass (right) 2.4 32 21 63.6 -0.12 4.7e-01 AAGAB AC103965.1 ADCY3 C1QTNF4 C6orf106 CCDC171 CDK6 CEP120 COPZ2 CYB5B DARS DLG1 DNAJC27 LIME1 MPHOSPH6 MTCH2 NOB1 OTUD4 PACSIN1 PIAS4 RAD9A RASA2 RP11-179B2.2 RP11-443B20.1 RP11-73O6.3 RP11-78I14.1 RPL10A SAR1B TBX6 WWP2 Y_RNA ZBTB38
Arm predicted mass (right) 5.6 100 81 245.5 0.94 1.2e-54 AC007566.10 ACPL2 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDHB BOK C12orf60 C6orf106 CCDC126 CD79B CDK6 CENPW CEP120 COG4 CRIPAK CXCR2 CYBRD1 DCAF16 DDX42 DDX6 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EDNRB EFEMP1 EPB41L2 FHL3 FKBP1B GDF5 GNA12 GPR126 GSDMC GSS H1FX HSD17B3 ILF3-AS1 IPO8 JMJD4 KIAA1614 LEMD3 LHFPL2 LINC00471 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MUC1 MXD3 NARFL NCOA1 NOV NPIPA2 OTUD4 PACSIN1 PLEKHA1 PNKD PPA2 PRPS1P2 PTCH1 RAB24 RAB43 RAD9A RAPSN RASA2 RIN3 RP11-104H15.8 RP11-179B2.2 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RPL10A RPS20 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 SYNE1 TBX6 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 UBXN2A UIMC1 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF76
Pulse rate, automated reading 1.6 12 7 21.2 -0.26 4.0e-01 AC103965.1 ACHE CEP120 DARS HSD17B3 MYO9A RASA2 ROM1 RP11-1055B8.4 RP11-382A20.2 ZBTB38 ZNF500
Alcohol intake frequency. 1.6 12 9 27.3 -0.84 2.9e-04 AC092667.2 C1QTNF4 FKBP1B LRRC37A LRRC37A2 MTCH2 PPA2 TBX6 TMED6 UBXN2A WWP2 Y_RNA
Comparative height size at age 10 8.6 141 124 375.8 0.94 3.8e-79 AAGAB AC007566.10 AC103965.1 ACPL2 ADCY3 ANAPC10 ANKRD13B ANKRD9 ANP32E AOC1 ARFGEF2 AXIN2 BCKDHB BOK C12orf60 C1QTNF4 C6orf106 CCDC126 CCDC47 CCS CD79B CDK6 CDO1 CENPO CENPW CEP120 CHMP1A CMIP CRIPAK CSE1L CTD-3074O7.12 CTD-3076O17.1 CXCR2 CYBRD1 DCAF16 DDX42 DHDDS DLEU2 DLG5 DMPK DNAJC27 DRAM1 E2F1 EBPL EFEMP1 EIF2AK4 EPB41L2 ERCC6L2 FAM136A FAM26F FARP2 FER FKBP1B GDF5 GNA12 GPR126 GSDMC GSS H1FX HIST2H2AA3 HOXB4 HSD17B3 IGFBP3 ILF3-AS1 IPO8 JMJD4 KANSL1 KIAA1614 KLHL7 LHFPL2 LOXL1-AS1 LRRC37A LRRC37A2 MAN2C1 MFSD10 MPHOSPH6 MRGPRF MRPL42 MST1P2 MTCH2 MXD3 MYADML2 MYO9A NARFL NCOA1 NOV OTUD4 PACSIN1 PIAS4 PIGF PIP4K2B PLCD3 PLEKHA1 PLEKHM1P PNKD PPA2 PTCH1 QSOX2 RAB24 RAB43 RAD9A RAPSN RASA2 RP11-179B2.2 RP11-196G18.22 RP11-196G18.24 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-443B20.1 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RP5-966M1.6 RPL10A RPS20 SCMH1 SEPT2 SERPINF1 SMARCD2 SUSD5 SYNE1 TBX6 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 U91328.21 UBXN2A UIMC1 Y_RNA ZBTB38 ZC3H11B ZCCHC24 ZFAS1 ZHX2 ZNF169 ZNF500 ZNF76
Suffer from 'nerves' 1.5 5 3 9.1 0.06 9.0e-01 C1QTNF4 KANSL1 LRRC37A2 MTCH2 Y_RNA
Overall health rating 1.4 9 2 6.1 -0.94 2.2e-05 AP000580.1 CCS CTD-3074O7.12 DCAF16 DPP3 MFSD10 PRPS1P2 RP11-1055B8.4 SNRPD2
Family relationship satisfaction 1.3 1 0 0.0 0.00 1.0e+00 ZFAS1
Knee pain experienced in last month 1.3 1 1 3.0 0.00 1.0e+00 GDF5
Hypertension (Self-reported) 1.5 10 6 18.2 -0.56 7.5e-02 ARFGEF2 CENPO DCAF16 DDB2 NCOA1 OSM PIAS4 RAPSN RP11-1055B8.4 RP11-538P18.2
Smoking status: Previous 1.4 1 0 0.0 0.00 1.0e+00 NOB1
Forced expiratory volume in 1-second (FEV1), predicted 7.1 66 41 124.2 0.96 9.2e-47 AC103965.1 ACHE ADCY3 ANAPC10 ANP32E BOK C6orf106 CD79B CDK6 CENPW CTD-3076O17.1 CYBRD1 DCAF16 DDX42 DLEU2 DNAJC27 E2F1 EBPL EFEMP1 ERCC6L2 FER GDF5 GNA12 GPR126 GSDMC GSS H1FX HIST2H2AA3 ILF3-AS1 JMJD4 LEMD3 LOXL1-AS1 MAN2C1 MPHOSPH6 MRPL42 MST1P2 MTCH2 MYO9A NARFL OTUD4 PACSIN1 PIP4K2B PTCH1 RAB24 RAD9A RASA2 RP11-196G18.24 RP11-435O5.4 RP11-435O5.5 RP11-443B20.1 RP11-690I21.1 RP11-73O6.3 RP11-977G19.11 RP5-966M1.6 RPL10A SCMH1 SMARCD2 TMEM180 TP53INP2 TSEN15 UIMC1 Y_RNA ZBTB38 ZHX2 ZNF500 ZNF76
Whole body fat-free mass 6.2 110 98 297.0 0.93 1.1e-58 AC007566.10 ACPL2 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDHB BOK C12orf60 C6orf106 CCDC126 CCDC47 CD79B CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CXCR2 CYBRD1 DCAF16 DDX42 DDX6 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 EPB41L2 FHL3 FKBP1B GDF5 GNA12 GPR126 GSDMC GSS H1FX HSD17B3 ILF3-AS1 IPO8 JMJD4 KIAA1614 LEMD3 LHFPL2 LINC00471 LOXL1-AS1 MAN2C1 MPHOSPH6 MRGPRF MRPL42 MUC1 MXD3 NARFL NCOA1 NOV NPIPA2 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PLEKHM1P PNKD PPA2 PRPS1P2 PTCH1 QSOX2 RAB24 RAB43 RAD9A RAPSN RASA2 RIN3 RP11-104H15.8 RP11-179B2.2 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RPL10A RPS20 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 SNAI3-AS1 SYNE1 TBX6 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 UBXN2A UIMC1 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF213 ZNF500 ZNF76
Leg fat-free mass (right) 5.1 104 77 233.3 0.93 1.3e-51 AC007566.10 ACPL2 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDHB BOK C12orf60 C6orf106 CCDC126 CD79B CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CYBRD1 DCAF16 DDX42 DLEU2 DLG5 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 EPB41L2 FHL3 FKBP1B GDF5 GNA12 GPR126 GSDMC GSS H1FX HIST2H2AA3 HSD17B3 ILF3-AS1 IPO8 JMJD4 KANSL1 KIAA1614 LHFPL2 LINC00471 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MUC1 MXD3 NARFL NCOA1 NOV NPIPA2 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PLEKHM1P PNKD PPA2 PRPS1P2 PTCH1 QSOX2 RAB24 RAB43 RAD9A RAPSN RASA2 RIN3 RP11-104H15.8 RP11-179B2.2 RP11-196G18.24 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-73O6.3 RP11-78I14.1 RPL10A RPS20 SCMH1 SEPT2 SLC38A2 SMARCD2 SMURF2 SNAI3-AS1 SYNE1 TBX6 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 UBXN2A UIMC1 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF500 ZNF76
Arm fat percentage (left) 3.4 39 26 78.8 -0.72 1.4e-08 AAGAB ADCY3 ANKRD13B ARFGEF2 C1QTNF4 CCDC171 CCS CD79B CENPW COPZ2 CTD-3074O7.12 CYB5B DCAF16 DDB2 DLG1 DNAJC27 DPP3 HIST2H2AA3 ICA1L KANSL1 LIME1 MTCH2 NCOA1 NFAT5 NOB1 NOV PDXDC2P PIAS4 PIGF RAPSN RP11-196G18.24 RP11-443B20.1 RP11-78I14.1 SAR1B TBX6 WWP2 Y_RNA ZFAS1 ZNF76
Handedness (chirality/laterality): Left-handed 1.3 4 3 9.1 1.00 1.8e-04 ARL17B KANSL1 LRRC37A LRRC37A2
Mood swings 1.5 6 3 9.1 -0.54 2.1e-01 AP000580.1 KANSL1 LRRC37A LRRC37A2 MTCH2 RP11-179B2.2
Loneliness, isolation 1.6 6 1 3.0 0.96 6.8e-04 ARFGEF2 C1QTNF4 CSE1L MTCH2 Y_RNA ZFAS1
Long-standing illness, disability or infirmity 1.5 3 1 3.0 0.00 1.0e+00 CCDC171 NOB1 ZGPAT
Diabetes diagnosed by doctor 1.8 2 0 0.0 0.00 1.0e+00 CENPW RCN2
Qualifications: nursing, teaching 1.2 1 0 0.0 0.00 1.0e+00 AXIN2
Mouth/teeth dental problems: Mouth ulcers 1.6 3 3 9.1 0.00 1.0e+00 CTSS LRRC37A LRRC37A2
Medication for cholesterol 1.5 1 1 3.0 0.00 1.0e+00 ZNF500
Breast cancer (self-reported) 1.1 1 0 0.0 0.00 1.0e+00 KLHL7
Asthma (self-reported) 1.7 6 3 9.1 -0.73 4.1e-02 AAGAB AHI1 CCS CTD-3074O7.12 U91328.21 ZNF76
Osteoporosis (self-reported) 1.2 1 0 0.0 0.00 1.0e+00 MRGPRF
Smoking status: Current 1.4 4 1 3.0 0.08 9.2e-01 ICA1L LIME1 MTCH2 PRPS1P2
Forced expiratory volume in 1-second (FEV1), predicted percentage 3.9 37 21 63.6 0.91 4.8e-15 AC073834.3 ANGPTL1 ARL17B BOK C10orf11 CEP120 CLUAP1 CTA-85E5.10 CTSS DHDDS GPR126 INTS12 JAG1 KANSL1 LIME1 LRRC37A LRRC37A2 NDST2 NOB1 NUDT5 OSM PDE12 PPA2 PSMA4 QSOX2 RIN3 RNF123 ROM1 RP11-382A20.2 RP11-538P18.2 RP11-967K21.1 RPL10A TRIM63 U91328.21 WWP2 ZGPAT ZNF76
Whole body water mass 6.1 108 95 287.9 0.94 2.1e-58 AC007566.10 ACPL2 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDHB BOK C12orf60 C6orf106 CCDC126 CD79B CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CXCR2 CYBRD1 DCAF16 DDX42 DDX6 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 EPB41L2 FHL3 FKBP1B GDF5 GNA12 GPR126 GSDMC GSS H1FX HSD17B3 ILF3-AS1 IPO8 JMJD4 KIAA1614 LEMD3 LHFPL2 LINC00471 LOXL1-AS1 MAN2C1 MPHOSPH6 MRGPRF MRPL42 MUC1 MXD3 NARFL NCOA1 NOV NPIPA2 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PNKD PPA2 PRPS1P2 PTCH1 QSOX2 RAB24 RAB43 RAD9A RAPSN RASA2 RIN3 RP11-104H15.8 RP11-179B2.2 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RPL10A RPS20 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 SNAI3-AS1 SYNE1 TBX6 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 UBXN2A UIMC1 ZBTB38 ZCCHC24 ZFAS1 ZHX2 ZMAT2 ZNF213 ZNF500 ZNF76
Leg predicted mass (right) 5.1 104 77 233.3 0.93 3.6e-52 AC007566.10 ACPL2 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDHB BOK C12orf60 C6orf106 CCDC126 CD79B CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CYBRD1 DCAF16 DDX42 DLEU2 DLG5 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 EPB41L2 FHL3 FKBP1B GDF5 GNA12 GPR126 GSDMC GSS H1FX HIST2H2AA3 HSD17B3 ILF3-AS1 IPO8 JMJD4 KANSL1 KIAA1614 LHFPL2 LINC00471 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MUC1 MXD3 NARFL NCOA1 NOV NPIPA2 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PLEKHM1P PNKD PPA2 PRPS1P2 PTCH1 QSOX2 RAB24 RAB43 RAD9A RAPSN RASA2 RIN3 RP11-104H15.8 RP11-179B2.2 RP11-196G18.24 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-73O6.3 RP11-78I14.1 RPL10A RPS20 SCMH1 SEPT2 SLC38A2 SMARCD2 SMURF2 SNAI3-AS1 SYNE1 TBX6 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 UBXN2A UIMC1 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF500 ZNF76
Arm fat mass (left) 2.6 36 21 63.6 -0.04 8.1e-01 AAGAB ADCY3 C1QTNF4 C6orf106 CCDC171 CCS CDK6 CEP120 COPZ2 CYB5B DNAJC27 GNA12 GSS HIST2H2AA3 KANSL1 LIME1 MTCH2 NOB1 OTUD4 PACSIN1 PDXDC2P PIAS4 RAB43 RAD9A RASA2 RP11-179B2.2 RP11-196G18.24 RP11-443B20.1 RP11-73O6.3 RP11-78I14.1 RPL10A TBX6 TP53INP2 WWP2 Y_RNA ZBTB38
Number of self-reported non-cancer illnesses 1.7 3 1 3.0 -0.11 8.9e-01 AAGAB CCS RBM4
Average weekly champagne plus white wine intake 1.3 1 0 0.0 0.00 1.0e+00 LRRC37A
Miserableness 1.4 5 2 6.1 -0.39 4.4e-01 LOXL1-AS1 LRRC37A LRRC37A2 MTCH2 RP11-179B2.2
Guilty feelings 1.5 2 0 0.0 0.00 1.0e+00 LRRC37A UBXN2A
Medication: Blood pressure 1.4 6 1 3.0 -0.01 9.9e-01 CHMP1A DDB2 LRRC37A RP11-1055B8.4 ZGPAT ZNF500
Supplements: Fish oil (including cod liver oil) 1.3 1 0 0.0 0.00 1.0e+00 NFAT5
High cholesterol (Self-reported) 1.5 3 0 0.0 0.00 1.0e+00 FAM136A ICA1L NOP58
Medication: Paracetamol 1.3 3 2 6.1 0.00 1.0e+00 LRRC37A LRRC37A2 U91328.21
Ever smoked 1.4 4 1 3.0 -0.28 7.2e-01 NOA1 NOB1 PRPS1P2 PSMA4
Basal metabolic rate 5.5 106 88 266.7 0.93 5.0e-56 AC007566.10 ACPL2 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDHB BOK C12orf60 C6orf106 CCDC126 CD79B CDK6 CENPW CEP120 CRIPAK CTC-228N24.3 CXCR2 CYBRD1 DCAF16 DDX42 DDX6 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 EPB41L2 FHL3 FKBP1B GDF5 GNA12 GPR126 GSDMC GSS H1FX HSD17B3 ILF3-AS1 IPO8 JMJD4 KANSL1 KIAA1614 LEMD3 LHFPL2 LINC00471 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MUC1 MXD3 NARFL NCOA1 NOV NPIPA2 OTUD4 PACSIN1 PIP4K2B PLEKHA1 PNKD PPA2 PRPS1P2 PTCH1 QSOX2 RAB24 RAB43 RAD9A RAPSN RASA2 RIN3 RP11-104H15.8 RP11-179B2.2 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RPL10A RPS20 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 SYNE1 TBX6 TMEM180 TNFSF10 TP53INP2 TPCN2 TRIM63 TSEN15 UBXN2A UIMC1 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF500 ZNF76
Leg fat percentage (left) 3.3 42 29 87.9 -0.88 2.1e-16 AAGAB AC073834.3 AC103965.1 ADCY3 ANKRD13B ARFGEF2 C1QTNF4 CCDC171 CD79B CENPW COPZ2 CTC-228N24.3 CXCL17 CYB5B DARS DCAF16 DDX42 DLG1 DNAJC27 GDF5 HMBS HSD17B3 ICA1L LIME1 MTCH2 NCOA1 NOB1 NOV PIAS4 PIGF PLEKHM1P RAPSN RIN3 RP11-435O5.5 RP11-443B20.1 SAR1B SMARCD2 WWP2 Y_RNA ZFAS1 ZGPAT ZNF76
Arm fat-free mass (left) 5.4 97 80 242.4 0.94 1.3e-52 AC007566.10 ACPL2 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDHB BOK C12orf60 C6orf106 CCDC126 CD79B CDK6 CENPW CEP120 CRIPAK CXCR2 CYBRD1 DCAF16 DDX42 DDX6 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 EPB41L2 FHL3 FKBP1B GDF5 GNA12 GPR126 GSDMC GSS H1FX ILF3-AS1 IPO8 JMJD4 KIAA1614 LEMD3 LHFPL2 LINC00471 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MUC1 MXD3 NARFL NCOA1 NOV NPIPA2 OTUD4 PACSIN1 PLEKHA1 PNKD PPA2 PTCH1 RAB24 RAB43 RAD9A RASA2 RIN3 RP11-104H15.8 RP11-179B2.2 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RPL10A RPS20 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 SYNE1 TBX6 TMEM180 TNFSF10 TP53INP2 TRIM63 TSEN15 UBXN2A UIMC1 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF76
Number of operations (self-reported) 1.6 2 1 3.0 0.00 1.0e+00 CCDC126 PPA2
Average weekly beer plus cider intake 1.1 1 0 0.0 0.00 1.0e+00 RNF123
Irritability 1.3 2 1 3.0 0.00 1.0e+00 LRRC37A LRRC37A2
Ever had prostate specific antigen (PSA) test 1.3 1 0 0.0 0.00 1.0e+00 ZBTB38
Fractured/broken bones in last 5 years 1.5 2 0 0.0 0.00 1.0e+00 AAGAB CRIPAK
Diastolic blood pressure, automated reading 1.6 17 8 24.2 -0.22 3.7e-01 AAGAB ACPL2 BCKDHB CEP120 DARS DCAF16 DDB2 FHL3 JAG1 MYO9A NCOA1 NOV PDE12 RP11-538P18.2 SCMH1 U91328.21 ZGPAT
Ever depressed for a whole week 1.1 1 0 0.0 0.00 1.0e+00 CSE1L
Myopia 1.6 3 1 3.0 0.00 1.0e+00 C1QTNF4 MTCH2 QSOX2
Vascular/heart problems diagnosed by doctor 1.5 9 4 12.1 0.62 5.7e-02 AAGAB CENPO DCAF16 DDB2 NFAT5 OSM PIAS4 RAPSN RP11-538P18.2
Cholesterol lowering medication 1.6 2 0 0.0 0.00 1.0e+00 ANKRD13B ICA1L
Pain experienced in last month 1.3 4 0 0.0 0.95 5.0e-02 CENPW KANSL1 LRRC37A2 PRPS1P2
Deep venous thrombosis (DVT) (self-reported) 1.1 1 1 3.0 0.00 1.0e+00 CACFD1
Heart disease (siblings) 1.4 1 0 0.0 0.00 1.0e+00 TP53INP2
Pack years of smoking 2.1 3 1 3.0 0.00 1.0e+00 CYB561 PIAS4 PSMA4
Impedance of whole body 2.3 49 31 93.9 0.11 4.4e-01 AC103965.1 ACHE ADCY3 ANP32E AOC1 ARL17B CCS CD79B CDO1 CENPW CEP120 COG4 CRIPAK CTC-228N24.3 CTD-3076O17.1 CYBRD1 DNAJC27 EDNRB EFEMP1 GDF5 GPR126 HIST2H2AA3 KANSL1 LOXL1-AS1 LRRC37A LRRC37A2 MRGPRF MRPL42 MST1P2 MUC1 OTUD4 PACSIN1 PASK PPA2 RAD9A RIN3 ROM1 RP11-179B2.2 RP11-196G18.24 RP11-382A20.2 RP11-425D10.10 RP11-443B20.1 RP11-73O6.3 RP5-966M1.6 RPL10A RPS20 SCMH1 SLC38A2 TBX6
Leg fat mass (left) 2.4 32 21 63.6 -0.12 4.6e-01 AAGAB AC103965.1 ADCY3 C1QTNF4 C6orf106 CCDC171 CDK6 CEP120 COPZ2 CYB5B DARS DLG1 DNAJC27 LIME1 MPHOSPH6 MTCH2 NOB1 OTUD4 PACSIN1 PIAS4 RAD9A RASA2 RP11-179B2.2 RP11-443B20.1 RP11-73O6.3 RP11-78I14.1 RPL10A SAR1B TBX6 WWP2 Y_RNA ZBTB38
Arm predicted mass (left) 5.3 100 80 242.4 0.93 2.9e-53 AC007566.10 ACPL2 ANAPC10 AOC1 ARFGEF2 AXIN2 BCKDHB BOK C12orf60 C6orf106 CCDC126 CD79B CDK6 CENPW CEP120 CHMP1A CRIPAK CXCR2 CYBRD1 DCAF16 DDX42 DDX6 DHDDS DLEU2 DLG5 DRAM1 E2F1 EBPL EDNRB EFEMP1 EIF2AK4 EPB41L2 FHL3 FKBP1B GDF5 GNA12 GPR126 GSDMC GSS H1FX HSD17B3 ILF3-AS1 IPO8 JMJD4 KIAA1614 LEMD3 LHFPL2 LOXL1-AS1 MPHOSPH6 MRGPRF MRPL42 MUC1 MXD3 NARFL NCOA1 NOV NPIPA2 OTUD4 PACSIN1 PLEKHA1 PNKD PPA2 PRPS1P2 PTCH1 RAB24 RAB43 RAD9A RASA2 RIN3 RP11-104H15.8 RP11-179B2.2 RP11-268J15.5 RP11-425D10.10 RP11-435O5.4 RP11-435O5.5 RP11-690I21.1 RP11-73O6.3 RP11-78I14.1 RPL10A RPS20 SCMH1 SEPT2 SERPINF1 SLC38A2 SMARCD2 SYNE1 TBX6 TMEM180 TNFSF10 TP53INP2 TPCN2 TRIM63 TSEN15 UBXN2A UIMC1 ZBTB38 ZCCHC24 ZHX2 ZMAT2 ZNF76

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 66 1.89 4.05
GTEx Adipose Visceral Omentum 50 2.46 4.43
GTEx Adrenal Gland 30 2.06 3.93
GTEx Artery Aorta 65 2.18 4.30
GTEx Artery Coronary 35 2.96 4.65
GTEx Artery Tibial 78 2.07 4.12
GTEx Brain Caudate basal ganglia 15 1.63 3.80
GTEx Brain Cerebellar Hemisphere 35 2.35 4.26
GTEx Brain Cerebellum 45 2.27 4.26
GTEx Brain Cortex 28 2.71 4.41
GTEx Brain Frontal Cortex BA9 19 2.06 4.21
GTEx Brain Hippocampus 15 2.86 4.51
GTEx Brain Hypothalamus 19 3.22 4.53
GTEx Brain Nucleus accumbens basal ganglia 22 2.54 4.54
GTEx Brain Putamen basal ganglia 11 1.76 4.08
GTEx Breast Mammary Tissue 44 2.23 4.35
GTEx Breast Mammary Tissue (Male) 33 2.77 4.84
GTEx Breast Mammary Tissue (Female) 32 1.95 4.11
GTEx Cells EBV-transformed lymphocytes 41 2.88 4.75
GTEx Cells Transformed fibroblasts 85 2.02 3.90
GTEx Colon Sigmoid 30 2.05 4.31
GTEx Colon Transverse 49 2.37 4.18
GTEx Esophagus Gastroesophageal Junction 33 2.28 4.34
GTEx Esophagus Mucosa 72 2.17 4.13
GTEx Esophagus Muscularis 77 2.38 4.38
GTEx Heart Atrial Appendage 40 2.53 4.58
GTEx Heart Left Ventricle 31 2.03 4.14
GTEx Liver 19 2.65 4.33
GTEx Lung 77 2.68 4.24
GTEx Muscle Skeletal 46 1.59 3.86
GTEx Nerve Tibial 95 2.20 4.08
GTEx Ovary 28 3.08 5.21
GTEx Pancreas 36 2.21 4.22
GTEx Pituitary 38 3.41 4.79
GTEx Prostate 15 1.80 3.99
GTEx Skin Not Sun Exposed Suprapubic 53 2.16 4.22
GTEx Skin Sun Exposed Lower leg 77 2.12 4.24
GTEx Small Intestine Terminal Ileum 15 3.25 4.97
GTEx Spleen 28 1.98 4.36
GTEx Stomach 35 2.41 4.33
GTEx Testis 73 2.31 4.28
GTEx Thyroid 80 2.00 4.08
GTEx Uterus 19 3.35 5.05
GTEx Vagina 15 2.36 4.23
GTEx Whole Blood 43 2.16 3.93
METSIM Adipose 68 1.48 3.41
NTR Blood 39 1.62 3.46
ROSMAP Brain Pre-frontal Cortex 63 1.43 3.39
YFS Blood 69 1.49 3.27
CommonMind Brain Pre-frontal Cortex 72 1.34 3.32
TCGA Breast Tumor 19 2.48 3.89
TCGA Breast Normal 54 1.28 3.08
TCGA Ovarian Tumor 39 1.33 3.24
TCGA Prostate Tumor 43 1.24 3.45