Hub : Traits :

Cardiovascular Disease

1815 significantly associated models · 511 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 994391 2404256 1 1 1.3e-07 9.2e-07 1.0e+00 100 NADK
2 1 5634851 7460433 4 1 9.3e-11 3.9e-07 5.9e-02 86 TNFRSF25
3 1 7715776 9571422 2 1 2.0e-07 9.0e-08 1.0e+00 100 RP5-1115A15.1
4 1 10435170 12600396 8 7 9.1e-29 6.5e-37 0.0e+00 -41300 AGTRAP CLCN6 NPPA NPPA-AS1 RP4-635E18.7
5 1 15314120 17490832 5 2 7.9e-10 1.7e-07 5.8e-01 99 PLEKHM2 RP4-798A10.2
6 1 24372971 28406173 9 4 1.9e-15 4.1e-13 2.4e-03 82 CD164L2 CLIC4 PIGV TMEM57
7 1 28823671 30246262 1 1 5.4e-08 3.7e-07 5.1e-02 85 MECR
8 1 41281595 43194594 1 1 1.8e-08 9.5e-10 1.2e-03 72 HIVEP3
9 1 62207254 63844736 2 1 1.8e-08 4.8e-09 8.4e-02 91 DOCK7
10 1 71163715 73435171 1 1 2.0e-07 2.4e-09 3.8e-05 52 NEGR1
11 1 88621347 90053563 1 1 2.0e-09 1.6e-08 3.5e-01 97 GTF2B
12 1 109098737 110733794 3 1 9.4e-24 7.6e-24 1.0e+00 100 PSRC1
13 1 112312154 113941737 4 1 2.1e-10 5.7e-16 3.7e-13 20 WNT2B
14 1 115486678 116932921 1 1 9.8e-08 1.9e-17 2.0e-15 13 VANGL1
15 1 201158976 202552839 1 1 1.2e-07 5.8e-11 3.6e-05 60 SHISA4
16 1 209712889 211117773 1 1 9.3e-08 9.4e-07 7.3e-05 35 SERTAD4
17 1 227598169 228995219 1 1 1.8e-08 6.6e-09 1.8e-05 45 MRPL55
18 1 230142626 231548480 1 1 3.6e-16 4.0e-16 7.0e-02 95 AGT
19 1 242590540 244345666 2 1 2.3e-08 2.7e-07 5.8e-01 99 SDCCAG8
20 2 20529948 21958745 1 1 9.3e-17 1.2e-17 1.0e+00 100 APOB
21 2 24021231 26068509 2 1 7.1e-11 1.6e-08 1.9e-01 95 NCOA1
22 2 26223547 29344127 13 9 3.5e-12 2.7e-38 NaN NaN AC074117.10 GPN1 GTF3C2 NRBP1 RP11-373D23.3 SLC35F6
23 2 42696855 44920960 5 3 2.8e-15 4.4e-19 5.2e-12 40 ABCG5 THADA ZFP36L2
24 2 64586858 66008960 1 1 6.0e-10 3.2e-09 1.0e+00 100 CEP68
25 2 72787254 74187703 1 1 2.3e-07 2.1e-06 7.0e-01 99 FBXO41
26 2 85420124 87126250 3 1 1.7e-10 3.3e-07 2.6e-02 81 MRPL35
27 2 97098095 98975985 2 1 7.2e-08 1.2e-06 1.8e-01 92 ACTR1B
28 2 112213244 113641631 1 1 3.6e-07 1.1e-06 4.9e-04 49 FBLN7
29 2 174238261 175980994 2 1 1.1e-07 2.1e-07 5.9e-01 99 OLA1
30 2 182305254 184084221 1 1 1.2e-07 2.8e-07 1.4e-03 61 PDE1A
31 2 218421136 219878756 3 1 2.5e-08 3.7e-08 1.5e-01 93 TMBIM1
32 3 10617048 12457119 2 1 2.6e-09 3.4e-10 2.7e-02 88 ATG7
33 3 26563909 28211713 2 1 1.3e-12 5.3e-15 9.4e-04 82 SLC4A7
34 3 38812165 40267321 1 1 3.5e-09 1.4e-07 2.7e-04 52 MOBP
35 3 46919379 50144951 12 4 3.3e-14 7.8e-15 1.0e+00 100 MRPS18AP1 NME6 SLC26A6 TCTA
36 3 53164803 54579051 1 1 7.6e-10 9.3e-13 3.8e-05 67 CHDH
37 3 133088362 134666475 1 1 1.2e-07 5.7e-08 1.0e+00 100 RYK
38 3 135273949 138894063 7 2 3.1e-14 1.8e-18 7.7e-06 74 DBR1 PCCB
39 3 149565982 151001026 1 1 3.6e-08 1.8e-09 1.7e-06 37 EIF2A
40 3 157567892 158980014 1 1 2.9e-07 7.6e-07 1.0e+00 100 RP11-538P18.2
41 3 168789705 170185994 1 1 1.7e-07 2.0e-14 1.5e-12 14 ACTRT3
42 3 183204923 184607480 1 1 4.2e-09 2.4e-07 9.7e-01 100 ABCF3
43 4 2598799 4082936 1 1 2.0e-09 2.2e-09 8.7e-05 57 RGS12
44 4 14310407 16125136 2 1 9.2e-09 2.5e-09 1.0e+00 100 CPEB2
45 4 17104059 18507692 1 1 1.3e-11 3.1e-10 2.6e-02 88 DCAF16
46 4 25880334 27452482 1 1 2.0e-08 2.1e-10 6.0e-08 27 TBC1D19
47 4 37915462 39361551 1 1 2.3e-08 1.3e-10 1.9e-07 34 FLJ13197
48 4 55517005 57014876 3 1 8.9e-08 4.0e-07 1.7e-01 93 SRD5A3-AS1
49 4 80488345 82578407 2 1 1.2e-23 2.0e-79 5.9e-58 28 C4orf22
50 4 83124080 84515968 1 1 1.6e-07 3.7e-07 1.0e+00 100 THAP9-AS1
51 4 102852939 104712494 7 1 5.8e-13 8.4e-15 2.1e-16 -12 CISD2
52 4 110590479 112179424 1 1 1.5e-07 4.2e-12 7.7e-08 40 ENPEP
53 4 155565971 157420901 4 2 1.1e-12 5.5e-20 8.1e-18 12 MAP9 RP11-588K22.2
54 5 32094654 33484084 1 1 1.5e-08 3.5e-37 3.4e-30 20 C5orf23
55 5 95400064 96840017 2 1 2.9e-09 3.4e-08 1.0e-02 78 CTD-2260A17.1
56 5 113910679 115330276 1 1 7.1e-09 1.0e-09 2.6e-03 76 CCDC112
57 5 126596610 128116643 1 1 3.5e-07 2.4e-11 7.2e-06 55 CTC-228N24.3
58 5 130936652 133140038 6 2 1.5e-08 4.3e-09 1.0e+00 100 AC004041.2 ZCCHC10
59 5 155651738 157087764 1 1 2.9e-08 2.9e-08 1.0e+00 100 TIMD4
60 5 176040488 177591495 4 1 9.5e-11 1.4e-10 6.9e-02 92 DBN1
61 6 14551209 16209635 1 1 7.2e-10 5.9e-08 8.9e-01 100 JARID2
62 6 33856903 35549670 3 1 3.0e-07 4.8e-07 1.0e+00 100 SNRPC
63 6 42258293 44034691 2 1 2.8e-14 1.7e-16 5.5e-04 82 ZNF318
64 6 78880271 80486611 2 1 2.6e-11 1.3e-10 1.0e+00 100 IRAK1BP1
65 6 124741508 128536730 5 3 3.3e-12 2.2e-30 1.3e-13 58 CENPW HEY2 PRELID1P1
66 6 159843841 161571560 2 1 1.8e-10 1.0e-19 1.2e-16 17 SLC22A1
67 7 1854263 3264728 1 1 1.6e-09 2.0e-10 4.0e-03 80 LFNG
68 7 6502367 7988091 1 1 4.1e-16 8.9e-16 2.9e-02 93 C1GALT1
69 7 26871554 28401337 1 1 2.0e-08 2.1e-17 2.6e-16 7 HIBADH
70 7 43885849 45276889 1 1 3.3e-10 3.0e-08 2.2e-01 95 NPC1L1
71 7 71935903 73340743 1 1 3.5e-07 6.1e-07 2.8e-01 95 NCF1B
72 7 73425238 75714883 6 2 2.1e-10 1.3e-08 9.7e-01 100 PMS2P5 STAG3L1
73 7 91380845 92776699 1 1 8.9e-09 2.4e-10 3.2e-04 68 GATAD1
74 7 99122437 100516003 1 1 5.4e-08 4.2e-07 6.2e-01 99 PVRIG
75 7 115619298 117135212 1 1 2.0e-07 2.1e-07 1.0e+00 100 MET
76 7 129342404 130779678 1 1 1.2e-08 3.0e-13 1.8e-12 7 CEP41
77 7 132241297 134834499 2 3 1.2e-09 5.2e-08 8.2e-01 100 AKR1B1 EXOC4
78 8 19064892 20521138 1 1 2.3e-08 1.0e-08 4.6e-02 88 LPL
79 8 25544268 26938804 1 1 7.1e-10 1.5e-15 3.8e-13 17 SDAD1P1
80 8 82017372 83452091 1 1 8.0e-10 5.9e-10 1.3e-01 94 SNX16
81 8 95199215 96825195 3 1 2.3e-10 6.9e-09 3.3e-01 97 NDUFAF6
82 8 102002608 103832256 2 1 1.8e-10 1.8e-09 3.0e-02 87 KB-1107E3.1
83 8 143110435 144515639 1 1 1.3e-08 9.3e-09 5.6e-03 77 THEM6
84 9 18674055 20075536 3 1 2.5e-09 1.4e-08 1.0e+00 100 RPS6
85 9 35208145 36597142 1 1 5.9e-08 3.8e-07 6.4e-02 87 HRCT1
86 10 18221643 19601824 2 1 4.9e-09 3.3e-16 4.1e-12 28 NSUN6
87 10 63856856 65606229 3 1 2.0e-16 1.2e-15 2.3e-02 92 NRBF2
88 10 74740461 77160682 3 1 1.4e-08 1.1e-07 1.2e-01 92 AP3M1
89 10 87729214 88960852 1 1 9.3e-08 1.5e-06 3.3e-01 96 LDB3
90 10 95379543 97055832 3 2 1.9e-10 1.3e-15 5.7e-04 81 NOC3L TBC1D12
91 10 103313599 105850787 9 1 1.0e-17 3.0e-19 7.7e-03 91 NT5C2
92 10 111268887 112741551 1 1 2.2e-08 1.5e-08 1.0e+00 100 MXI1
93 11 1213806 2705175 3 1 8.8e-17 1.1e-22 9.6e-12 52 TNNT3
94 11 9003306 10471931 1 1 2.7e-16 1.6e-19 4.7e-06 74 SWAP70
95 11 16532857 18068163 1 1 6.1e-10 1.1e-07 2.0e-03 66 NUCB2
96 11 29646947 31048683 1 1 3.1e-08 1.1e-07 2.7e-09 -25 ARL14EP
97 11 42881882 44596817 2 1 1.7e-10 1.3e-09 2.7e-01 97 RP11-613D13.5
98 11 46033104 48783497 14 6 3.5e-18 4.3e-15 NaN NaN ACP2 C11orf49 FNBP4 NR1H3 PTPRJ
99 11 63305184 66333072 7 6 1.1e-16 2.8e-16 5.7e-02 95 CTSW RNASEH2C SIPA1 SNX15 VEGFB
100 11 99859184 101559718 2 1 2.9e-41 1.0e-40 1.0e+00 100 ARHGAP42
101 11 106485489 108027561 2 1 8.9e-13 4.1e-14 2.1e-03 83 CWF19L2
102 11 110776537 112491227 4 1 5.1e-11 5.4e-11 1.0e+00 100 C11orf1
103 11 115953897 117800682 5 2 1.2e-18 3.2e-18 3.3e-02 94 PAFAH1B2 ZNF259
104 12 47671905 49444545 5 1 1.1e-10 1.8e-10 7.6e-02 92 SENP1
105 12 49673158 51256065 4 2 4.8e-11 8.5e-11 1.0e+00 100 AQP5 CERS5
106 12 53822670 55216415 1 1 4.5e-08 8.6e-17 2.2e-12 29 LOC400043
107 12 57317393 58716588 1 1 9.8e-08 8.3e-07 7.2e-02 87 SLC26A10
108 12 69045442 70476863 2 1 2.2e-09 5.8e-08 1.6e-02 80 YEATS4
109 12 89116708 90799212 4 2 6.2e-23 3.9e-28 1.1e-01 98 ATP2B1 LOC338758
110 12 109591369 113517494 19 8 1.5e-26 3.7e-35 NaN NaN AC003029.1 ADAM1A GLTP NAA25 RP3-462E2.5 SH2B3 TMEM116
111 12 121048935 122706844 3 1 2.4e-13 1.6e-13 1.0e+00 100 RNF34
112 12 132369172 133778796 1 1 4.4e-08 4.0e-08 1.0e+00 100 FBRSL1
113 13 29641514 31108727 1 1 7.0e-08 9.9e-10 4.0e-03 78 UBL3
114 13 114302502 115106996 2 1 2.1e-09 2.8e-09 1.0e+00 100 UPF3A
115 14 35173418 36571554 1 1 3.9e-08 1.3e-11 1.8e-05 60 NFKBIA
116 14 50401104 51830366 1 1 1.1e-07 4.5e-08 1.6e-03 67 SAV1
117 14 70676661 72273020 1 1 2.3e-10 3.2e-09 3.8e-02 88 PCNX
118 14 103161201 104866687 7 1 6.9e-09 5.1e-08 9.4e-01 100 APOPT1
119 15 40360741 42820589 11 1 4.9e-15 1.4e-13 4.6e-01 99 CHP1
120 15 67138238 68789191 1 1 7.9e-08 2.8e-08 1.5e-03 67 MAP2K5
121 15 68897072 70384464 1 1 2.6e-07 3.1e-07 1.4e-04 45 PAQR5
122 15 73664741 76108550 15 8 1.4e-24 6.4e-24 NaN NaN ARID3B COX5A CSK CYP11A1 MPI RPP25 ULK3
123 15 80293439 81936479 2 1 1.9e-15 3.8e-16 4.9e-02 94 KIAA1199
124 15 90712555 92135418 2 1 2.8e-33 5.3e-30 4.3e-01 100 FES
125 16 86671 1032776 1 1 1.7e-08 1.6e-10 1.5e-03 76 PDIA2
126 16 1402493 2830389 1 1 3.4e-07 1.0e-07 9.8e-03 76 TSC2
127 16 3015262 5593819 3 3 1.1e-10 1.2e-10 6.0e-05 61 AC006111.1 GLYR1
128 16 29711343 31892919 17 1 1.6e-12 1.3e-12 1.0e+00 100 VKORC1
129 16 68467643 72845749 14 4 4.2e-12 2.1e-12 1.8e-03 80 CIRH1A HPR PDXDC2P SF3B3
130 16 74635632 76197034 2 1 8.8e-10 1.6e-09 1.0e+00 100 CFDP1
131 16 89013848 90172696 8 1 1.2e-12 1.1e-13 1.0e+00 100 SPATA33
132 17 629675 2249904 2 1 3.5e-08 3.7e-07 7.8e-02 88 CRK
133 17 3371501 4766937 1 1 6.2e-08 2.7e-07 4.7e-01 98 RP11-810M2.2
134 17 7044746 8484683 2 1 5.2e-09 3.7e-09 1.3e-01 93 LSMD1
135 17 26888725 29985248 9 2 6.7e-10 2.0e-08 5.8e-03 76 CTD-2349P21.5 NUFIP2
136 17 38092713 39502398 1 1 1.4e-07 1.0e-07 6.4e-02 88 SMARCE1
137 17 42413481 43570226 3 1 1.9e-08 1.2e-08 1.5e-03 69 NMT1
138 17 44788310 48139500 25 6 2.1e-16 6.2e-22 8.3e-14 40 AC002558.1 GOSR2 HOXB7 NPEPPS RP11-463M16.4 RP1-62O9.3
139 17 55681549 57920532 4 1 5.4e-09 4.9e-10 5.1e-05 58 BZRAP1-AS1
140 17 58828402 60172573 2 1 3.3e-09 4.3e-09 2.4e-02 85 RP11-332H18.4
141 17 60858059 62599864 8 5 4.4e-24 7.1e-25 1.0e+00 100 ACE DDX42 FTSJ3 PSMC5
142 17 73128150 74629867 8 1 6.4e-11 7.6e-12 3.9e-02 91 FBF1
143 17 75977988 77462467 2 1 7.7e-10 2.8e-10 1.0e+00 100 USP36
144 17 78665405 80023050 1 1 7.0e-10 2.0e-07 1.5e-05 31 RP11-1055B8.4
145 18 69836 1512239 1 1 2.6e-07 7.1e-08 1.0e+00 100 YES1
146 18 20393480 21863589 2 1 2.2e-11 5.5e-11 1.0e+00 100 C18orf8
147 19 1163934 2560423 2 1 4.7e-09 2.7e-09 1.0e+00 100 CTB-31O20.6
148 19 7793502 9200017 1 1 6.0e-08 3.7e-07 6.0e-01 99 MARCH2
149 19 10016470 12196190 6 2 1.6e-12 4.0e-24 9.5e-13 50 EPOR RGL3
150 19 16462417 18180451 4 2 9.3e-19 7.1e-19 1.0e+00 100 CTD-3032J10.3 MYO9B
151 19 21206463 22643745 1 1 2.9e-07 6.3e-07 4.2e-03 67 ZNF100
152 19 44614208 46098885 3 3 1.5e-11 4.9e-64 3.5e-48 26 BCAM PVRL2 TOMM40
153 19 48464978 50108983 5 1 2.3e-18 4.7e-19 1.0e+00 100 RASIP1
154 20 7419920 9648826 1 1 7.1e-11 1.4e-25 1.8e-16 38 PLCB1
155 20 29927166 31615615 3 2 6.0e-10 2.6e-07 2.0e-05 31 C20orf160 TSPY26P
156 20 56858751 58262841 2 1 2.6e-08 4.7e-37 8.4e-32 15 TH1L
157 20 61522825 62912463 7 5 5.0e-20 2.2e-17 NaN NaN GMEB2 OPRL1 RGS19 TCEA2 ZBTB46
158 21 44392270 45879403 2 1 1.7e-07 4.6e-10 1.2e-08 16 PDXK
159 22 19262852 20330744 2 1 2.1e-07 2.8e-08 1.7e-02 81 AC006547.14
160 22 28792887 30261219 1 1 8.8e-08 2.6e-08 2.0e-04 56 KREMEN1

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Alzheimer’s Disease (in mother) 1.54 2 2 6.1 0.00 1.0e+00 BCAM TOMM40
Alzheimer’s Disease (in father) 1.22 1 0 0.0 0.00 1.0e+00 TOMM40
Alzheimer’s Disease (including proxy) 2.20 5 3 9.1 0.18 7.8e-01 ACE BCAM PVRIG TOMM40 VKORC1
Crohns Disease (2017) 1.49 8 5 15.2 -0.40 3.3e-01 AC004041.2 AC074117.10 AP3M1 RASIP1 RP11-373D23.3 TCTA TMBIM1 ZFP36L2
Irritable Bowel Disease (IBD) 1.59 11 5 15.2 0.00 9.9e-01 AC004041.2 AC074117.10 GMEB2 GTF3C2 NRBP1 OPRL1 PMS2P5 RGS19 RP11-373D23.3 TMBIM1 ZFP36L2
Ulcerative Colitis (UC) 1.41 3 1 3.0 0.00 1.0e+00 OPRL1 RGS19 TMBIM1
Major Depression (MDD) 1.26 2 1 3.0 0.00 1.0e+00 FES NEGR1
Reaction Time 1.60 6 3 9.1 0.81 5.1e-02 AC003029.1 NAA25 OLA1 SH2B3 TCTA TMEM116
Verbal and Numeric Reasoning (VNR) 1.33 4 3 9.1 -0.50 5.0e-01 ACP2 DCAF16 FBXO41 NEGR1
Breast Cancer 1.86 10 4 12.1 0.10 7.8e-01 CSK FES NR1H3 NUFIP2 RNASEH2C RP11-1055B8.4 SIPA1 SLC4A7 TNNT3 ZCCHC10
Age at First Birth 1.18 1 1 3.0 0.00 1.0e+00 TCTA
Body Mass Index (BMI) (2010) 1.83 3 2 6.1 0.00 1.0e+00 MAP2K5 NEGR1 STAG3L1
Coronary Artery Disease (CAD) 2.55 5 4 12.1 0.99 8.4e-04 DBR1 EPOR PSRC1 RP11-463M16.4 SLC22A1
Crohns Disease (2012) 1.30 3 1 3.0 0.00 1.0e+00 AC004041.2 RASIP1 TCTA
Fasting Glucose 2.64 6 5 15.2 -0.97 1.1e-05 AC074117.10 ACP2 FNBP4 GTF3C2 NR1H3 NRBP1
HbA1C 1.32 2 0 0.0 0.00 1.0e+00 ADAM1A RP3-462E2.5
HDL Cholesterol 3.38 11 6 18.2 -0.81 1.3e-03 ACP2 C11orf49 CTSW LPL NR1H3 PIGV PSRC1 SIPA1 SNRPC TOMM40 ZNF259
LDL Cholesterol 8.19 16 14 42.4 0.70 2.4e-03 AC003029.1 APOB BCAM DOCK7 EPOR HPR NPC1L1 PAFAH1B2 PIGV PSRC1 PVRL2 RASIP1 SH2B3 TIMD4 TOMM40 ZNF259
Lupus 1.41 1 0 0.0 0.00 1.0e+00 SNRPC
Primary Biliary Cirrhosis 1.39 1 1 3.0 0.00 1.0e+00 SH2B3
Rheumatoid Arthritis 1.26 1 0 0.0 0.00 1.0e+00 SH2B3
Schizophrenia 1.61 9 3 9.1 -0.25 5.1e-01 APOPT1 C11orf49 CERS5 CISD2 FES NT5C2 NUCB2 PCCB SDCCAG8
Triglycerides 10.11 15 12 36.4 0.89 9.9e-07 AC074117.10 APOB DOCK7 GPN1 GTF3C2 HPR LPL NCF1B NRBF2 NRBP1 PAFAH1B2 RP11-373D23.3 TIMD4 VKORC1 ZNF259
Type 2 Diabetes (T2D) 1.69 1 0 0.0 0.00 1.0e+00 CISD2
Ulcerative Colitis 1.44 1 0 0.0 0.00 1.0e+00 TMBIM1
Blood Eosinophil Count 3.08 40 28 84.8 0.53 3.8e-04 AC002558.1 AC003029.1 AC004041.2 AC006547.14 ACTR1B ACTRT3 ADAM1A AP3M1 APOPT1 BCAM CD164L2 CERS5 CIRH1A FBF1 FLJ13197 GATAD1 GLTP HIVEP3 LPL NAA25 NDUFAF6 NFKBIA NUCB2 PDXK PIGV PVRL2 RNASEH2C RP3-462E2.5 RP5-1115A15.1 SH2B3 SIPA1 SMARCE1 THAP9-AS1 TMEM116 TOMM40 TSPY26P UPF3A VKORC1 ZFP36L2 ZNF259
Blood Platelet Count 3.08 76 57 172.7 0.10 4.0e-01 ABCF3 AC002558.1 AC003029.1 AC004041.2 AC006547.14 AC074117.10 ADAM1A AGTRAP AP3M1 C18orf8 C20orf160 CERS5 CFDP1 CLCN6 CLIC4 COX5A CRK CSK CTD-2260A17.1 CTD-2349P21.5 CTSW CWF19L2 DCAF16 DDX42 DOCK7 FBF1 FLJ13197 FNBP4 GATAD1 GMEB2 GOSR2 GPN1 GTF2B GTF3C2 HIVEP3 HPR IRAK1BP1 KREMEN1 LFNG MPI MYO9B NAA25 NCF1B NMT1 NRBF2 NRBP1 NUCB2 NUFIP2 PAFAH1B2 PCCB PIGV PTPRJ RASIP1 RGS12 RNASEH2C RP11-373D23.3 RP11-463M16.4 RPP25 SAV1 SENP1 SH2B3 SIPA1 SLC26A10 SLC4A7 SNRPC SNX16 TBC1D12 TH1L TIMD4 TMBIM1 TOMM40 WNT2B YES1 ZFP36L2 ZNF259 ZNF318
Blood Red Count 1.86 63 42 127.3 0.62 3.1e-08 AC003029.1 ACTRT3 ADAM1A APOPT1 ARID3B C20orf160 C4orf22 CENPW CLCN6 CLIC4 COX5A CRK CSK CYP11A1 DDX42 FBF1 FBRSL1 FLJ13197 FTSJ3 GMEB2 GOSR2 GTF2B HIVEP3 HPR LSMD1 MPI MRPS18AP1 NAA25 NCOA1 NDUFAF6 NME6 NPEPPS NPPA NT5C2 NUFIP2 PDIA2 PDXK PSMC5 PTPRJ PVRIG RNASEH2C RP11-332H18.4 RP3-462E2.5 RP4-798A10.2 RPP25 SENP1 SH2B3 SIPA1 SLC35F6 SNX15 SPATA33 SRD5A3-AS1 TBC1D12 TCTA TH1L TIMD4 TMEM116 TSPY26P ULK3 USP36 VEGFB VKORC1 ZNF100
Blood White Count 2.86 52 37 112.1 0.59 1.6e-06 AC003029.1 AC004041.2 AC006111.1 AC006547.14 AC074117.10 ACP2 ADAM1A APOPT1 ARHGAP42 C18orf8 CERS5 CRK DCAF16 DDX42 FBF1 FBLN7 FES FLJ13197 FTSJ3 GATAD1 GLYR1 GPN1 GTF3C2 KB-1107E3.1 LSMD1 MOBP NAA25 NCF1B NFKBIA NPEPPS NRBF2 NRBP1 NT5C2 NUCB2 NUFIP2 PCCB PSMC5 PTPRJ RP11-373D23.3 RP3-462E2.5 RP5-1115A15.1 SH2B3 SLC26A6 TBC1D12 THADA THAP9-AS1 TIMD4 TMBIM1 TMEM116 TSC2 VEGFB VKORC1
Heel T-Score 1.87 43 35 106.1 0.01 9.3e-01 ACP2 APOPT1 ARHGAP42 ARL14EP ATG7 C20orf160 CPEB2 CTD-2260A17.1 CTSW DCAF16 FBLN7 FLJ13197 FNBP4 GATAD1 GTF2B KREMEN1 LFNG LSMD1 MARCH2 NCOA1 NEGR1 NFKBIA NMT1 NR1H3 NT5C2 PAQR5 PDE1A PLEKHM2 PSRC1 PTPRJ RP11-810M2.2 RP4-635E18.7 RP4-798A10.2 RP5-1115A15.1 SIPA1 TCTA THADA TMBIM1 TNFRSF25 TSC2 VKORC1 ZCCHC10 ZNF318
BMI 2.31 56 35 106.1 0.73 8.4e-11 AC006111.1 AC006547.14 ACP2 ACTR1B APOPT1 ARL14EP BZRAP1-AS1 C11orf49 C18orf8 C20orf160 C4orf22 CEP41 CHDH CHP1 CIRH1A COX5A CTB-31O20.6 CTSW EXOC4 FBF1 FLJ13197 HEY2 HIVEP3 HPR KB-1107E3.1 KIAA1199 MAP2K5 NEGR1 NRBF2 NT5C2 NUFIP2 OLA1 PCCB PDIA2 PDXDC2P PLEKHM2 PMS2P5 PSMC5 RNF34 RP11-463M16.4 RP11-538P18.2 RP11-613D13.5 RP5-1115A15.1 RPP25 SF3B3 SHISA4 SIPA1 SNRPC SNX15 STAG3L1 TCTA TNFRSF25 TSPY26P USP36 VKORC1 ZNF318
Height 1.90 98 80 242.4 -0.50 9.5e-08 ABCG5 AC002558.1 AC003029.1 AC004041.2 AC006111.1 AC074117.10 ACE ACP2 ACTR1B APOPT1 ARHGAP42 ARL14EP BZRAP1-AS1 C11orf1 C11orf49 C18orf8 CCDC112 CENPW CERS5 CFDP1 CHP1 CLIC4 CRK CTC-228N24.3 CTD-2349P21.5 CTSW CYP11A1 DBN1 DBR1 DCAF16 DDX42 EPOR FES FTSJ3 GATAD1 GLYR1 GOSR2 GPN1 GTF2B GTF3C2 HEY2 HIVEP3 HOXB7 HRCT1 LPL MARCH2 MET MRPL55 NCF1B NCOA1 NFKBIA NMT1 NPEPPS NRBP1 NT5C2 NUCB2 NUFIP2 PDE1A PDXDC2P PIGV PRELID1P1 PSMC5 PSRC1 PTPRJ RASIP1 RP11-1055B8.4 RP11-332H18.4 RP11-373D23.3 RP11-463M16.4 RP11-538P18.2 RP11-810M2.2 RP1-62O9.3 RP4-635E18.7 RP4-798A10.2 RP5-1115A15.1 RYK SDAD1P1 SERTAD4 SH2B3 SIPA1 SLC26A10 SLC35F6 SLC4A7 SNRPC SRD5A3-AS1 STAG3L1 TBC1D12 THEM6 TMBIM1 TMEM57 TNNT3 TSC2 UPF3A USP36 WNT2B YEATS4 ZNF259 ZNF318
Waist Hip Ratio (WHR) 1.90 34 25 75.8 0.60 1.3e-04 ADAM1A C5orf23 CEP41 CTD-3032J10.3 CTSW CYP11A1 DBN1 DBR1 FNBP4 KREMEN1 LOC400043 MYO9B NCF1B NCOA1 OPRL1 PCCB PCNX RASIP1 RGS19 RP11-332H18.4 SERTAD4 SIPA1 SLC22A1 SNRPC SRD5A3-AS1 SWAP70 TBC1D19 TCEA2 TCTA TMBIM1 VEGFB ZCCHC10 ZFP36L2 ZNF318
Systolic Blood Pressure 9.65 168 132 400.0 0.96 1.2e-103 ABCF3 AC002558.1 AC003029.1 AC006111.1 AC006547.14 AC074117.10 ACE ACP2 ACTRT3 ADAM1A AGT AGTRAP AKR1B1 AP3M1 AQP5 ARHGAP42 ARID3B ARL14EP ATG7 ATP2B1 BZRAP1-AS1 C11orf1 C1GALT1 C20orf160 C4orf22 C5orf23 CCDC112 CD164L2 CENPW CEP68 CERS5 CFDP1 CHP1 CLCN6 CLIC4 COX5A CPEB2 CRK CSK CTB-31O20.6 CTC-228N24.3 CTD-3032J10.3 CTSW CWF19L2 CYP11A1 DBR1 DCAF16 EIF2A ENPEP EXOC4 FBF1 FBLN7 FBRSL1 FBXO41 FES FLJ13197 FNBP4 GATAD1 GLTP GLYR1 GMEB2 GOSR2 GPN1 GTF2B GTF3C2 HIBADH HOXB7 HRCT1 IRAK1BP1 KB-1107E3.1 KIAA1199 KREMEN1 LDB3 LFNG LOC338758 LSMD1 MECR MET MPI MRPL35 MRPL55 MRPS18AP1 MYO9B NAA25 NADK NCOA1 NDUFAF6 NFKBIA NME6 NMT1 NOC3L NPPA NPPA-AS1 NR1H3 NRBF2 NRBP1 NSUN6 NT5C2 NUCB2 OLA1 OPRL1 PAFAH1B2 PDE1A PDXK PIGV PLCB1 PLEKHM2 PMS2P5 PRELID1P1 PTPRJ RASIP1 RGL3 RGS19 RNASEH2C RNF34 RP11-1055B8.4 RP11-332H18.4 RP11-373D23.3 RP11-463M16.4 RP11-538P18.2 RP11-588K22.2 RP3-462E2.5 RP4-635E18.7 RP4-798A10.2 RP5-1115A15.1 RPP25 RPS6 RYK SAV1 SDAD1P1 SENP1 SF3B3 SH2B3 SIPA1 SLC22A1 SLC26A10 SLC26A6 SLC4A7 SNX16 SPATA33 SRD5A3-AS1 STAG3L1 SWAP70 TBC1D12 TBC1D19 TCEA2 TCTA TH1L THADA THAP9-AS1 THEM6 TMBIM1 TMEM116 TNFRSF25 TNNT3 TOMM40 UBL3 ULK3 UPF3A USP36 VEGFB WNT2B YES1 ZBTB46 ZCCHC10 ZFP36L2 ZNF100 ZNF318
Smoking Status 1.28 11 0 0.0 0.51 1.1e-01 ADAM1A CTSW FES KIAA1199 MAP2K5 MET OLA1 RP11-463M16.4 RP5-1115A15.1 SERTAD4 SNRPC
Allergy or Eczema 2.00 18 6 18.2 0.26 2.9e-01 AC004041.2 AC074117.10 ADAM1A C11orf1 CFDP1 CHP1 GMEB2 NEGR1 NMT1 NRBP1 PLEKHM2 PVRL2 RNF34 RP11-373D23.3 RP5-1115A15.1 SMARCE1 TMBIM1 ULK3
Hypothyroidism (self reported) 2.04 10 7 21.2 0.76 6.9e-03 AC002558.1 AC003029.1 ADAM1A MRPS18AP1 NAA25 RASIP1 RP5-1115A15.1 SH2B3 TMEM116 TMEM57
Respiratory disease 1.29 6 3 9.1 0.77 7.1e-02 AC004041.2 CHP1 FBF1 GMEB2 NMT1 RP5-1115A15.1
Type 2 Diabetes (T2D) 2.92 17 7 21.2 0.39 8.5e-02 AC074117.10 ACE C1GALT1 CTSW DBR1 GTF3C2 LOC400043 NDUFAF6 NRBP1 PMS2P5 PRELID1P1 SH2B3 SIPA1 TCTA VEGFB ZBTB46 ZFP36L2
Lung FEV1/FVC ratio 1.54 28 18 54.5 -0.18 3.6e-01 ARHGAP42 ATG7 ATP2B1 C1GALT1 CENPW CEP41 CFDP1 CTB-31O20.6 KB-1107E3.1 LOC400043 MARCH2 MET NEGR1 NFKBIA NRBF2 NUFIP2 PMS2P5 PSRC1 PVRIG RASIP1 RP11-810M2.2 SHISA4 THADA THAP9-AS1 TNFRSF25 TSPY26P ZCCHC10 ZFP36L2
Lung FVC 1.22 22 13 39.4 -0.35 1.1e-01 C18orf8 C1GALT1 CHP1 CTC-228N24.3 DBR1 DCAF16 GMEB2 MAP2K5 NCOA1 NRBF2 OPRL1 RP11-332H18.4 RP11-538P18.2 RP11-613D13.5 SF3B3 SNRPC TCEA2 TNFRSF25 USP36 VKORC1 ZBTB46 ZCCHC10
Neuroticism 1.17 5 3 9.1 0.71 1.8e-01 MAP2K5 NR1H3 NT5C2 PCCB RP5-1115A15.1
Chronotype (morning person) 1.33 4 0 0.0 0.99 1.3e-03 AC003029.1 ACP2 NAA25 RP11-810M2.2
Hair Pigment 1.03 34 23 69.7 0.16 3.4e-01 AC003029.1 AC006547.14 AC074117.10 ACP2 APOPT1 ATP2B1 C11orf49 C20orf160 C4orf22 CTSW DBR1 EPOR FES FLJ13197 GOSR2 GPN1 GTF3C2 HOXB7 LOC338758 NRBP1 NUCB2 PCNX PIGV RGS19 RP11-373D23.3 RP4-798A10.2 RP5-1115A15.1 SAV1 SH2B3 SIPA1 SNX15 SPATA33 TSPY26P ZFP36L2
Tanning 1.17 11 5 15.2 -0.58 2.9e-02 AC074117.10 DBN1 GPN1 GTF3C2 NCF1B NRBF2 NRBP1 SH2B3 SPATA33 TSPY26P ULK3
Hand grip strength (left) 1.18 4 2 6.1 0.83 1.7e-01 ABCG5 DCAF16 FES TSC2
Number of treatments/medications taken 3.83 13 4 12.1 -0.97 8.2e-09 ABCG5 AC074117.10 ACE ADAM1A ARHGAP42 CHP1 CISD2 DCAF16 FBXO41 KIAA1199 PSRC1 SERTAD4 SH2B3
Average weekly spirits intake 1.21 1 0 0.0 0.00 1.0e+00 RASIP1
Sensitivity / hurt feelings 1.04 1 0 0.0 0.00 1.0e+00 FES
Hearing difficulty/problems: Yes 1.31 3 2 6.1 0.00 1.0e+00 AP3M1 NCF1B ZNF318
Relative age of first facial hair 1.28 3 2 6.1 0.00 1.0e+00 ATG7 C4orf22 SIPA1
Systolic blood pressure, automated reading 6.60 90 60 181.8 -0.98 2.0e-69 AC002558.1 AC003029.1 AC006111.1 AC006547.14 ACP2 ACTRT3 AGT AGTRAP AP3M1 AQP5 ARHGAP42 ARL14EP ATG7 ATP2B1 C4orf22 C5orf23 CEP68 CERS5 CFDP1 CHP1 CLCN6 CRK CSK CTB-31O20.6 CTC-228N24.3 CTSW CWF19L2 DCAF16 FBXO41 FES FLJ13197 FNBP4 GATAD1 GLTP GLYR1 GMEB2 GOSR2 GTF2B HOXB7 IRAK1BP1 KIAA1199 LFNG MPI MRPS18AP1 MYO9B NAA25 NCOA1 NFKBIA NME6 NMT1 NOC3L NR1H3 NRBF2 NSUN6 NT5C2 NUCB2 OLA1 OPRL1 PDIA2 PIGV PLEKHM2 PMS2P5 PRELID1P1 RGS19 RP11-332H18.4 RP11-588K22.2 RP3-462E2.5 RP4-635E18.7 RP5-1115A15.1 RPP25 SAV1 SF3B3 SH2B3 SIPA1 SLC26A6 SLC4A7 STAG3L1 SWAP70 TBC1D12 TCEA2 TCTA TMBIM1 TMEM116 TNNT3 ULK3 UPF3A USP36 WNT2B YES1 ZBTB46
Eye problems/disorders: Diabetes related eye disease 1.32 1 0 0.0 0.00 1.0e+00 PSMC5
Angina 2.81 7 2 6.1 -0.98 1.1e-04 APOPT1 FES OPRL1 PSRC1 RGS19 SLC22A1 TCEA2
Medication: Metformin 2.11 2 0 0.0 0.00 1.0e+00 AC074117.10 TCTA
Impedance of leg (right) 1.79 38 22 66.7 0.01 9.6e-01 ABCF3 AC006547.14 AC074117.10 ARHGAP42 ATG7 CEP41 CERS5 CTB-31O20.6 CTC-228N24.3 CTD-3032J10.3 CTSW DBN1 FES HEY2 KIAA1199 LOC400043 MAP2K5 MYO9B NCF1B NEGR1 NFKBIA NOC3L NT5C2 PAQR5 PDXDC2P PMS2P5 RP11-463M16.4 RP11-613D13.5 RP1-62O9.3 SENP1 SHISA4 SLC35F6 SNRPC STAG3L1 SWAP70 TBC1D12 VKORC1 ZNF318
Leg fat-free mass (left) 1.91 36 26 78.8 0.08 6.5e-01 ABCF3 AC006547.14 AC074117.10 C18orf8 CENPW CLIC4 CTC-228N24.3 CTD-2349P21.5 DBN1 DCAF16 EPOR GATAD1 GLYR1 GPN1 GTF3C2 HEY2 HIVEP3 KIAA1199 MAP2K5 NCF1B NEGR1 NFKBIA NRBP1 NT5C2 PDE1A PRELID1P1 RP11-332H18.4 RP11-613D13.5 SHISA4 SLC35F6 SNRPC STAG3L1 ULK3 UPF3A USP36 VKORC1
Trunk fat percentage 1.88 29 14 42.4 -0.66 8.4e-05 ACP2 C11orf49 C18orf8 CHP1 CTB-31O20.6 CTSW DBR1 FNBP4 HIVEP3 MAP2K5 MYO9B NEGR1 NOC3L PDIA2 PDXDC2P RNF34 RP11-613D13.5 RP11-810M2.2 RP5-1115A15.1 SHISA4 SNRPC SRD5A3-AS1 STAG3L1 TBC1D12 TCTA TNFRSF25 TSC2 UPF3A VKORC1
Hand grip strength (right) 1.28 5 4 12.1 0.96 1.0e-02 ABCG5 DCAF16 JARID2 TSC2 WNT2B
Townsend deprivation index at recruitment 1.11 1 0 0.0 0.00 1.0e+00 MAP2K5
Maternal smoking around birth 1.40 2 0 0.0 0.00 1.0e+00 APOPT1 C20orf160
Fed-up feelings 1.19 3 1 3.0 0.54 4.6e-01 AC003029.1 NR1H3 SH2B3
Relative age voice broke 1.34 1 0 0.0 0.00 1.0e+00 RP11-613D13.5
Taking other prescription medications 2.00 3 1 3.0 0.00 1.0e+00 ADAM1A SH2B3 ZNF318
Age when periods started (menarche) 1.62 13 7 21.2 0.70 7.9e-03 ACP2 CTB-31O20.6 CTSW MAP2K5 NEGR1 NFKBIA NMT1 NUCB2 PDXDC2P PMS2P5 RP11-613D13.5 SIPA1 STAG3L1
Heel bone mineral density (BMD) T-score, automated (left) 1.44 7 6 18.2 -0.07 8.8e-01 APOPT1 GATAD1 KREMEN1 LSMD1 RP5-1115A15.1 SIPA1 TCTA
High blood pressure 9.93 167 110 333.3 -0.99 1.8e-146 ABCF3 ABCG5 AC002558.1 AC003029.1 AC006111.1 AC006547.14 ACE ACP2 ACTRT3 ADAM1A AGT AGTRAP AKR1B1 AP3M1 APOPT1 AQP5 ARHGAP42 ARID3B ATG7 ATP2B1 C11orf1 C11orf49 C1GALT1 C20orf160 C4orf22 CCDC112 CD164L2 CENPW CEP41 CEP68 CERS5 CFDP1 CHDH CHP1 CISD2 CLCN6 CLIC4 COX5A CSK CTB-31O20.6 CTC-228N24.3 CTD-2260A17.1 CTD-3032J10.3 CTSW CWF19L2 CYP11A1 DBN1 DBR1 DCAF16 ENPEP EXOC4 FBF1 FBXO41 FES FLJ13197 FNBP4 GLTP GLYR1 GMEB2 GOSR2 GTF2B HEY2 HIBADH HIVEP3 HRCT1 IRAK1BP1 JARID2 KB-1107E3.1 KIAA1199 KREMEN1 LDB3 LFNG LOC338758 LSMD1 MAP2K5 MARCH2 MET MOBP MPI MRPL55 MRPS18AP1 MYO9B NAA25 NADK NCOA1 NDUFAF6 NEGR1 NME6 NMT1 NOC3L NPPA NPPA-AS1 NR1H3 NRBF2 NSUN6 NT5C2 NUCB2 OLA1 OPRL1 PAQR5 PCCB PCNX PDE1A PDIA2 PDXK PIGV PLCB1 PLEKHM2 PMS2P5 PRELID1P1 PTPRJ PVRIG RASIP1 RGS19 RNF34 RP11-1055B8.4 RP11-332H18.4 RP11-373D23.3 RP11-463M16.4 RP11-538P18.2 RP11-588K22.2 RP11-613D13.5 RP11-810M2.2 RP1-62O9.3 RP3-462E2.5 RP4-635E18.7 RP4-798A10.2 RP5-1115A15.1 RPP25 RYK SAV1 SDAD1P1 SDCCAG8 SENP1 SF3B3 SH2B3 SIPA1 SLC26A10 SLC26A6 SLC35F6 SLC4A7 SNX16 SPATA33 STAG3L1 SWAP70 TBC1D12 TBC1D19 TCEA2 TH1L THAP9-AS1 THEM6 TMEM116 TMEM57 TNFRSF25 TNNT3 TSC2 TSPY26P UBL3 ULK3 UPF3A VANGL1 VEGFB VKORC1 WNT2B YEATS4 ZBTB46 ZNF318
Hayfever, allergic rhinitis or eczema 1.93 10 6 18.2 -0.26 4.6e-01 AC004041.2 AC074117.10 ADAM1A C11orf1 CHP1 NRBP1 PVRL2 RP11-373D23.3 RP5-1115A15.1 SMARCE1
Supplements: Glucosamine 1.50 2 1 3.0 0.00 1.0e+00 CSK NRBF2
Medication: Atenolol 3.78 4 2 6.1 -0.95 4.9e-02 ARHGAP42 FES MET SH2B3
Medication: Levothyroxine sodium 2.04 7 5 15.2 -0.99 3.2e-07 AC003029.1 ADAM1A NAA25 RP3-462E2.5 SH2B3 SNRPC TMEM116
Sitting height 1.47 38 24 72.7 0.47 2.0e-03 AC074117.10 APOPT1 ARL14EP C20orf160 C5orf23 CENPW CERS5 CHP1 DCAF16 GATAD1 GLYR1 GOSR2 GPN1 GTF2B GTF3C2 HEY2 HOXB7 HPR JARID2 KIAA1199 MARCH2 NCF1B NFKBIA NRBP1 NUFIP2 PRELID1P1 PTPRJ RASIP1 RP11-463M16.4 RP11-538P18.2 SLC35F6 SLC4A7 SNRPC SRD5A3-AS1 TBC1D12 TMBIM1 TSC2 UPF3A
High blood pressure (mother) 3.90 12 3 9.1 -0.96 7.6e-07 AGT ARHGAP42 CENPW CLCN6 FES NT5C2 NUCB2 PIGV SENP1 SLC4A7 TNFRSF25 TNNT3
Body mass index (BMI) 2.14 33 20 60.6 -0.79 2.4e-08 AC006547.14 ACP2 APOPT1 C11orf49 C18orf8 CEP41 COX5A CTB-31O20.6 CTSW EXOC4 HEY2 HIVEP3 KIAA1199 MAP2K5 NEGR1 NT5C2 NUFIP2 OLA1 PCCB PDIA2 PDXDC2P PMS2P5 RP11-613D13.5 RP5-1115A15.1 RPP25 SF3B3 SHISA4 SIPA1 SNRPC STAG3L1 TCTA TNFRSF25 VKORC1
Impedance of leg (left) 1.77 36 24 72.7 0.01 9.3e-01 ABCF3 AC006547.14 AC074117.10 ARHGAP42 ATG7 CEP41 CERS5 CTB-31O20.6 CTC-228N24.3 CTD-3032J10.3 CTSW DBN1 FES HEY2 KIAA1199 MAP2K5 MYO9B NCF1B NEGR1 NFKBIA NOC3L NT5C2 PAQR5 PDXDC2P PMS2P5 RP11-463M16.4 RP11-613D13.5 RP1-62O9.3 SHISA4 SLC35F6 SNRPC STAG3L1 SWAP70 TBC1D12 VKORC1 ZNF318
Leg predicted mass (left) 1.90 36 26 78.8 0.08 6.5e-01 ABCF3 AC006547.14 AC074117.10 C18orf8 CENPW CLIC4 CTC-228N24.3 CTD-2349P21.5 DBN1 DCAF16 EPOR GATAD1 GLYR1 GPN1 GTF3C2 HEY2 HIVEP3 KIAA1199 MAP2K5 NCF1B NEGR1 NFKBIA NRBP1 NT5C2 PDE1A PRELID1P1 RP11-332H18.4 RP11-613D13.5 SHISA4 SLC35F6 SNRPC STAG3L1 ULK3 UPF3A USP36 VKORC1
Trunk fat mass 1.90 32 18 54.5 -0.58 5.1e-04 ACP2 C18orf8 CTB-31O20.6 CTSW DBR1 FNBP4 HEY2 HIVEP3 HPR KB-1107E3.1 KIAA1199 MAP2K5 NEGR1 NT5C2 OLA1 PDIA2 PDXDC2P PTPRJ RP11-613D13.5 RP11-810M2.2 RP5-1115A15.1 RPP25 SHISA4 SNRPC SRD5A3-AS1 STAG3L1 TCTA TNFRSF25 TSC2 UPF3A USP36 VKORC1
Waist circumference 2.19 31 18 54.5 -0.69 1.6e-05 AC006547.14 C18orf8 COX5A CTB-31O20.6 CTSW CYP11A1 FNBP4 HEY2 HIVEP3 KB-1107E3.1 KIAA1199 MAP2K5 NEGR1 NUFIP2 OLA1 PCCB PDIA2 PDXDC2P PMS2P5 RP11-613D13.5 RP11-810M2.2 RPP25 SHISA4 SIPA1 SNRPC STAG3L1 TCTA TNFRSF25 ULK3 USP36 VKORC1
Number of incorrect matches in round 1.17 1 1 3.0 0.00 1.0e+00 VKORC1
Past tobacco smoking 1.45 7 1 3.0 0.72 6.8e-02 AC003029.1 ADAM1A C18orf8 MAP2K5 RP3-462E2.5 SH2B3 TMEM116
Alcohol usually taken with meals 1.31 1 0 0.0 0.00 1.0e+00 NEGR1
Nervous feelings 1.10 3 0 0.0 0.00 1.0e+00 NR1H3 NT5C2 PCCB
Frequency of tenseness / restlessness in last 2 weeks 1.03 1 0 0.0 0.00 1.0e+00 NT5C2
Hearing difficulty/problems with background noise 1.62 4 1 3.0 0.25 7.5e-01 APOPT1 CSK ULK3 ZNF318
Hair/balding pattern: Pattern 2 1.48 3 2 6.1 0.00 1.0e+00 C4orf22 CPEB2 NMT1
Had menopause 1.66 5 3 9.1 0.66 7.6e-02 AC074117.10 CHP1 GTF3C2 NRBP1 RNASEH2C
Forced vital capacity (FVC) 1.37 16 7 21.2 0.62 9.8e-03 ACP2 C11orf49 CENPW CTC-228N24.3 DCAF16 DDX42 GATAD1 GMEB2 MRPL55 NCOA1 NUFIP2 RP11-538P18.2 TMBIM1 UPF3A VKORC1 WNT2B
Heel bone mineral density (BMD) T-score, automated (right) 1.46 9 5 15.2 -0.05 8.9e-01 ACP2 APOPT1 DCAF16 GATAD1 KREMEN1 LSMD1 RP5-1115A15.1 SIPA1 TCTA
Qualifications: None of the above 1.24 4 1 3.0 -0.49 5.1e-01 CPEB2 EXOC4 IRAK1BP1 NEGR1
Mouth/teeth dental problems 1.47 3 0 0.0 0.00 1.0e+00 APOPT1 RASIP1 SIPA1
Heart attack 2.46 3 2 6.1 0.00 1.0e+00 FES PCCB PSRC1
Allergy 1.74 10 6 18.2 0.28 4.4e-01 AC004041.2 C11orf1 CHP1 FES GMEB2 NMT1 RP11-373D23.3 RP5-1115A15.1 SMARCE1 TMBIM1
Diabetes (self-reported) 2.40 6 3 9.1 -0.12 7.7e-01 AC074117.10 GTF3C2 NRBP1 PMS2P5 TCTA ZBTB46
Medication: Ramipril 3.79 4 2 6.1 -0.99 5.7e-03 ADAM1A ARHGAP42 CSK FES
Medication: Simvastatin 5.70 26 15 45.5 -0.95 5.8e-14 ABCG5 AC074117.10 APOB BCAM CTD-2349P21.5 DOCK7 EPOR FES HPR LPL NPC1L1 NPEPPS OPRL1 PAFAH1B2 PIGV PSRC1 PVRL2 RASIP1 RGS19 SIPA1 TCEA2 TIMD4 TOMM40 VEGFB YEATS4 ZNF259
Fluid intelligence score 1.31 4 3 9.1 0.57 4.3e-01 ACP2 DCAF16 FBXO41 NEGR1
Illnesses of siblings 3.36 8 1 3.0 0.95 3.5e-04 FES FLJ13197 MRPS18AP1 NUFIP2 PDIA2 PRELID1P1 SH2B3 VKORC1
Neuroticism score 1.08 1 1 3.0 0.00 1.0e+00 NR1H3
Weight 2.00 43 22 66.7 -0.30 5.0e-02 AC006547.14 AC074117.10 C18orf8 CTB-31O20.6 CTD-2349P21.5 CTSW DCAF16 EPOR GATAD1 GLYR1 GPN1 GTF3C2 HEY2 HIVEP3 HPR KB-1107E3.1 KIAA1199 MAP2K5 MET NCF1B NEGR1 NFKBIA NRBP1 NT5C2 OLA1 PDIA2 PDXDC2P PMS2P5 PTPRJ RP11-332H18.4 RP11-613D13.5 RP11-810M2.2 RPP25 SF3B3 SH2B3 SHISA4 SNRPC STAG3L1 TCTA ULK3 UPF3A USP36 VKORC1
Impedance of arm (right) 1.80 42 21 63.6 0.19 2.2e-01 AC006547.14 AC074117.10 ACTR1B BZRAP1-AS1 CERS5 CISD2 CTB-31O20.6 CTD-3032J10.3 CTSW CYP11A1 EIF2A EXOC4 GPN1 HEY2 KIAA1199 KREMEN1 LOC400043 MARCH2 MET MYO9B NCF1B NEGR1 NOC3L NRBF2 PAQR5 PCCB PDE1A PMS2P5 RP11-373D23.3 RP11-463M16.4 RP1-62O9.3 RYK SENP1 SHISA4 SLC4A7 SNRPC SNX16 STAG3L1 TBC1D12 TSPY26P ULK3 VKORC1
Arm fat percentage (right) 1.98 30 19 57.6 -0.79 2.2e-07 ACP2 APOPT1 C11orf49 C18orf8 CHP1 CPEB2 CTB-31O20.6 CTSW DCAF16 FBF1 FNBP4 HIVEP3 HPR MAP2K5 NEGR1 NT5C2 NUFIP2 OLA1 PDIA2 PDXDC2P PMS2P5 RP11-613D13.5 RP5-1115A15.1 SHISA4 SIPA1 SNRPC STAG3L1 TCTA TNFRSF25 VKORC1
Trunk fat-free mass 2.09 45 32 97.0 0.40 4.7e-03 AC003029.1 AC074117.10 C18orf8 CCDC112 CENPW CTD-2349P21.5 CTD-3032J10.3 DBN1 DCAF16 DDX42 EPOR GATAD1 GLYR1 GPN1 GTF3C2 HEY2 HIVEP3 JARID2 KIAA1199 MARCH2 MET MYO9B NCF1B NCOA1 NFKBIA NMT1 NRBP1 NT5C2 PDE1A PRELID1P1 PSRC1 RASIP1 RP11-332H18.4 RP11-373D23.3 RP11-613D13.5 SH2B3 SHISA4 SLC35F6 SLC4A7 SNRPC TBC1D12 TMBIM1 ULK3 UPF3A USP36
Hip circumference 2.02 35 16 48.5 -0.26 1.2e-01 AC006547.14 ACP2 C18orf8 CCDC112 CLCN6 CTB-31O20.6 DCAF16 FBF1 HEY2 HIVEP3 HPR KB-1107E3.1 KIAA1199 MAP2K5 NCF1B NEGR1 NFKBIA NPPA NT5C2 OLA1 PDIA2 PDXDC2P PMS2P5 RASIP1 RP11-613D13.5 SF3B3 SH2B3 SHISA4 SNRPC SRD5A3-AS1 STAG3L1 UPF3A USP36 VEGFB VKORC1
Alcohol intake versus 10 years previously 1.72 5 1 3.0 0.85 6.9e-02 AC074117.10 GTF3C2 HIBADH NEGR1 RASIP1
Father's age at death 2.01 3 2 6.1 0.00 1.0e+00 FES PSRC1 SH2B3
Worrier / anxious feelings 1.24 2 0 0.0 0.00 1.0e+00 CPEB2 NT5C2
Hair/balding pattern: Pattern 3 1.37 1 1 3.0 0.00 1.0e+00 C4orf22
Forced expiratory volume in 1-second (FEV1) 1.30 14 2 6.1 0.45 1.1e-01 ARHGAP42 C11orf49 C1GALT1 DCAF16 EPOR MRPL55 NCOA1 NFKBIA NRBF2 RP11-538P18.2 TMBIM1 UPF3A VKORC1 ZCCHC10
Pulse rate 1.29 3 1 3.0 0.00 1.0e+00 AC074117.10 MET TCTA
Qualifications: A levels/AS levels or equivalent 1.32 5 1 3.0 0.64 2.4e-01 DCAF16 EXOC4 FBXO41 NEGR1 STAG3L1
Mouth/teeth dental problems: Dentures 1.37 4 1 3.0 -1.00 4.2e-03 EXOC4 PMS2P5 RASIP1 RP11-1055B8.4
Asthma 1.42 4 3 9.1 -0.96 3.6e-02 AC004041.2 C11orf1 NMT1 RP5-1115A15.1
Medication: Cholesterol lowering 6.25 32 18 54.5 -0.93 1.8e-15 ABCG5 AC074117.10 APOB ARHGAP42 BCAM CHP1 DOCK7 EPOR FES GPN1 GTF3C2 HPR LPL NPEPPS NRBP1 OPRL1 PAFAH1B2 PCCB PIGV PSRC1 PVRIG PVRL2 RASIP1 RGS19 SIPA1 SLC22A1 TCEA2 TIMD4 TNFRSF25 TOMM40 YEATS4 ZNF259
Depression (self-reported) 0.95 1 0 0.0 0.00 1.0e+00 RP5-1115A15.1
Illnesses of mother 2.78 1 1 3.0 0.00 1.0e+00 FES
Forced expiratory volume in 1-second (FEV1), Best measure 1.39 11 4 12.1 0.73 1.1e-02 ACP2 C11orf49 C1GALT1 DCAF16 EPOR NFKBIA NRBF2 RP11-538P18.2 UPF3A VKORC1 ZCCHC10
Pulse wave Arterial Stiffness index 1.63 2 1 3.0 0.00 1.0e+00 ADAM1A VEGFB
Impedance of arm (left) 1.74 38 20 60.6 0.18 2.9e-01 AC006547.14 AC074117.10 ACTR1B CERS5 CISD2 CTD-3032J10.3 CTSW CYP11A1 EIF2A EXOC4 GPN1 HEY2 KIAA1199 KREMEN1 LOC400043 MARCH2 MYO9B NCF1B NEGR1 NOC3L NRBF2 PCCB PDE1A RP11-373D23.3 RP11-463M16.4 RP11-613D13.5 RP1-62O9.3 RYK SH2B3 SHISA4 SLC4A7 SNRPC STAG3L1 TBC1D12 TNNT3 TSPY26P ULK3 VKORC1
Arm fat mass (right) 2.01 32 16 48.5 -0.74 1.5e-06 ACP2 APOPT1 C11orf49 C18orf8 COX5A CTB-31O20.6 CTSW FNBP4 HEY2 HIVEP3 HPR KIAA1199 MAP2K5 NEGR1 NT5C2 OLA1 PDIA2 PDXDC2P PMS2P5 RP11-613D13.5 RP11-810M2.2 RP5-1115A15.1 RPP25 SF3B3 SHISA4 SIPA1 SNRPC STAG3L1 TCTA TNFRSF25 USP36 VKORC1
Trunk predicted mass 2.11 46 31 93.9 0.38 6.8e-03 AC003029.1 AC074117.10 C18orf8 CCDC112 CENPW CTD-2349P21.5 CTD-3032J10.3 DBN1 DCAF16 DDX42 EPOR GATAD1 GLYR1 GPN1 GTF3C2 HEY2 HIVEP3 JARID2 KIAA1199 MARCH2 MET MYO9B NCF1B NCOA1 NEGR1 NFKBIA NMT1 NRBP1 NT5C2 PDE1A PRELID1P1 PSRC1 RASIP1 RP11-332H18.4 RP11-373D23.3 RP11-613D13.5 SH2B3 SHISA4 SLC35F6 SLC4A7 SNRPC TBC1D12 TMBIM1 ULK3 UPF3A USP36
Standing height 1.76 58 42 127.3 0.49 4.9e-05 AC004041.2 AC074117.10 ACP2 APOPT1 ARL14EP C11orf49 C18orf8 CENPW CERS5 CFDP1 CHP1 CLIC4 CTD-2349P21.5 DBN1 DCAF16 DDX42 EPOR FTSJ3 GATAD1 GLYR1 GTF2B GTF3C2 HEY2 HIVEP3 HOXB7 MARCH2 NCF1B NCOA1 NFKBIA NMT1 NRBP1 NUFIP2 PDE1A PDXDC2P PIGV PRELID1P1 PSMC5 PSRC1 PTPRJ RASIP1 RP11-1055B8.4 RP11-332H18.4 RP11-463M16.4 RP11-538P18.2 RP11-810M2.2 RP1-62O9.3 RP4-635E18.7 RP5-1115A15.1 RYK SH2B3 SIPA1 SLC4A7 SNRPC TMBIM1 TSC2 UPF3A USP36 ZNF318
Tense / 'highly strung' 1.16 3 1 3.0 0.00 1.0e+00 NT5C2 RP5-1115A15.1 THAP9-AS1
Seen doctor (GP) for nerves, anxiety, tension or depression 1.21 1 1 3.0 0.00 1.0e+00 NEGR1
Hair/balding pattern: Pattern 4 1.37 7 2 6.1 -0.51 2.4e-01 C4orf22 CENPW CERS5 CLIC4 PRELID1P1 RP5-1115A15.1 ZCCHC10
Birth weight of first child 2.35 14 3 9.1 0.98 4.9e-10 AC003029.1 AGTRAP CLCN6 COX5A CSK CTC-228N24.3 DCAF16 FES GTF2B OPRL1 RPP25 SH2B3 STAG3L1 TBC1D12
Peak expiratory flow (PEF) 1.23 5 2 6.1 0.81 9.4e-02 C1GALT1 DCAF16 NUFIP2 RASIP1 ZFP36L2
Mouth/teeth dental problems: Bleeding gums 1.40 1 0 0.0 0.00 1.0e+00 C11orf49
Medication: Paracetamol 1.51 1 1 3.0 0.00 1.0e+00 SDCCAG8
Headache pain in last month 1.45 1 1 3.0 0.00 1.0e+00 SDCCAG8
Medication for cholesterol, blood pressure or diabetes 6.98 47 19 57.6 0.98 3.3e-32 ABCG5 AC002558.1 ACE APOB ARHGAP42 ATP2B1 C11orf1 C4orf22 CHP1 CLCN6 CSK CTC-228N24.3 CTD-2349P21.5 CTD-3032J10.3 CTSW EPOR FES FLJ13197 JARID2 KIAA1199 LFNG MRPL35 NME6 NPC1L1 NPEPPS OPRL1 PAFAH1B2 PDXK PLCB1 PSRC1 PVRIG RGS19 RP1-62O9.3 SENP1 SERTAD4 SH2B3 SIPA1 SLC22A1 SLC4A7 TCEA2 TCTA TSPY26P UPF3A WNT2B YEATS4 ZBTB46 ZNF259
Gout (self-reported) 2.78 7 5 15.2 0.28 4.3e-01 AC074117.10 GPN1 GTF3C2 NCF1B NRBP1 SH2B3 SIPA1
Hypothyroidism/myxoedema (self-reported) 1.84 6 5 15.2 -0.87 1.1e-02 AC003029.1 ADAM1A NAA25 RP5-1115A15.1 SH2B3 TMEM116
Medication: Amlodipine 4.34 15 9 27.3 -0.96 7.3e-09 ARHGAP42 C11orf49 CD164L2 CLCN6 FES FLJ13197 GLYR1 KIAA1199 RNF34 RP4-635E18.7 SENP1 SLC35F6 TNNT3 WNT2B ZNF318
Birth weight 1.95 12 5 15.2 0.96 6.4e-07 AC003029.1 ADAM1A C11orf1 CFDP1 CTD-2349P21.5 DBN1 DCAF16 FES RP3-462E2.5 SH2B3 THADA TMEM116
High blood pressure (siblings) 3.92 12 4 12.1 -0.96 5.5e-07 ACP2 APOPT1 ARHGAP42 CLCN6 FES NR1H3 NRBF2 PDIA2 PRELID1P1 SH2B3 TNNT3 VKORC1
Forced vital capacity (FVC), Best measure 1.39 14 6 18.2 0.69 4.2e-03 ABCG5 ACP2 C11orf49 CENPW CTC-228N24.3 DCAF16 EPOR GMEB2 NCOA1 NUFIP2 RP11-538P18.2 TMBIM1 UPF3A VKORC1
Body fat percentage 2.04 33 16 48.5 -0.73 1.6e-06 ACP2 APOPT1 C11orf49 C18orf8 CHP1 COX5A CRK CTB-31O20.6 CTSW DCAF16 FNBP4 HIVEP3 MAP2K5 NEGR1 NOC3L NUFIP2 OLA1 PDIA2 PDXDC2P PMS2P5 RP11-613D13.5 RP11-810M2.2 RP5-1115A15.1 RPP25 SHISA4 SNRPC SRD5A3-AS1 STAG3L1 TBC1D12 TCTA TNFRSF25 TSC2 VKORC1
Leg fat percentage (right) 2.21 34 21 63.6 -0.83 1.4e-09 ACP2 APOPT1 C11orf49 C18orf8 CHP1 COX5A CRK CTB-31O20.6 CTC-228N24.3 CTSW DCAF16 GTF2B HIVEP3 MAP2K5 MOBP NEGR1 NMT1 NOC3L NUFIP2 OLA1 PDIA2 PDXDC2P RP11-613D13.5 RP11-810M2.2 RP5-1115A15.1 RPP25 SHISA4 SNRPC SRD5A3-AS1 STAG3L1 TBC1D12 TCTA TNFRSF25 VKORC1
Arm fat-free mass (right) 2.15 42 29 87.9 0.19 2.2e-01 AC006547.14 AC074117.10 C18orf8 CENPW CTD-2349P21.5 CTSW DBN1 DCAF16 EPOR GATAD1 GLYR1 GPN1 GTF3C2 HEY2 HIVEP3 KIAA1199 MAP2K5 MARCH2 MET MYO9B NCF1B NEGR1 NFKBIA NMT1 NRBP1 PDE1A PRELID1P1 PSRC1 RASIP1 RP11-332H18.4 RP11-373D23.3 RP11-613D13.5 SH2B3 SHISA4 SLC35F6 SNRPC TCTA TMBIM1 ULK3 UPF3A USP36 VKORC1
Comparative body size at age 10 1.86 15 6 18.2 -0.06 8.2e-01 ACP2 AQP5 ATG7 C11orf49 C18orf8 CERS5 MAP2K5 NEGR1 NME6 RASIP1 SIPA1 SLC26A6 SNRPC VKORC1 ZNF318
Worry too long after embarrassment 1.21 3 0 0.0 0.00 1.0e+00 FTSJ3 PCCB PSMC5
Wheeze or whistling in the chest in last year 1.51 4 1 3.0 -0.48 5.2e-01 C11orf1 GMEB2 NMT1 VKORC1
Age at first live birth 1.20 1 0 0.0 0.00 1.0e+00 DCAF16
Pulse wave peak to peak time 1.63 1 1 3.0 0.00 1.0e+00 ADAM1A
Shortness of breath walking on level ground 1.09 2 0 0.0 0.00 1.0e+00 C18orf8 USP36
Qualifications: College or University degree 1.39 14 5 15.2 0.73 2.8e-03 C18orf8 CPEB2 DCAF16 EXOC4 FBXO41 GTF2B MET NEGR1 RGS12 SDCCAG8 SHISA4 STAG3L1 TNFRSF25 VKORC1
Medication for pain relief, constipation, heartburn 1.80 5 0 0.0 1.00 1.5e-04 AC074117.10 C20orf160 KIAA1199 SDCCAG8 YEATS4
Medication: Blood pressure 6.90 52 24 72.7 -0.98 2.3e-40 AC003029.1 ACE ACP2 ADAM1A ARHGAP42 ATP2B1 C11orf1 C20orf160 C4orf22 CCDC112 CEP41 CISD2 CLCN6 CSK CTC-228N24.3 CTSW CWF19L2 CYP11A1 DCAF16 FBXO41 FES FLJ13197 FNBP4 JARID2 KIAA1199 LFNG MOBP MRPL35 MRPS18AP1 NME6 NOC3L NR1H3 PDXK PLCB1 PRELID1P1 PVRIG RNF34 RP11-463M16.4 RP11-810M2.2 RP1-62O9.3 RP4-635E18.7 SENP1 SH2B3 SLC26A6 SLC4A7 SPATA33 TNNT3 TSPY26P ULK3 UPF3A WNT2B ZBTB46
Angina (self-reported) 2.77 7 3 9.1 -0.97 2.2e-04 APOPT1 FES OPRL1 PSRC1 RGS19 SLC22A1 TCEA2
Migraine (self-reported) 1.40 1 0 0.0 0.00 1.0e+00 C11orf49
Medication: Allopurinol 2.49 5 4 12.1 -0.78 2.2e-02 AC074117.10 GPN1 GTF3C2 NCF1B NRBP1
Medication: Omeprazole 1.18 1 0 0.0 0.00 1.0e+00 SNRPC
Mean time to correctly identify matches 1.61 7 3 9.1 -0.83 2.2e-02 AC003029.1 NAA25 OLA1 RP11-810M2.2 SH2B3 TCTA TMEM116
Whole body fat mass 1.98 35 17 51.5 -0.63 4.5e-05 ACP2 C11orf49 C18orf8 CTB-31O20.6 CTSW DBR1 FNBP4 HEY2 HIVEP3 HPR KB-1107E3.1 KIAA1199 MAP2K5 NEGR1 NT5C2 OLA1 PDIA2 PDXDC2P PMS2P5 PTPRJ RP11-613D13.5 RP11-810M2.2 RP5-1115A15.1 RPP25 SF3B3 SHISA4 SNRPC SRD5A3-AS1 STAG3L1 TCTA TNFRSF25 TSC2 UPF3A USP36 VKORC1
Leg fat mass (right) 2.12 32 16 48.5 -0.86 4.5e-10 ACP2 C18orf8 CTB-31O20.6 CTSW HEY2 HIVEP3 HPR KB-1107E3.1 KIAA1199 MAP2K5 MET MOBP NEGR1 NUFIP2 OLA1 PDIA2 PDXDC2P PMS2P5 RP11-613D13.5 RP11-810M2.2 RP5-1115A15.1 RPP25 SF3B3 SHISA4 SNRPC STAG3L1 TCTA TNFRSF25 TSPY26P ULK3 USP36 VKORC1
Arm predicted mass (right) 2.12 40 29 87.9 0.16 3.1e-01 AC006547.14 AC074117.10 C18orf8 CENPW CTD-2349P21.5 DBN1 DCAF16 EPOR GATAD1 GLYR1 GPN1 GTF3C2 HEY2 HIVEP3 KIAA1199 MAP2K5 MARCH2 MET NCF1B NEGR1 NFKBIA NRBP1 PDE1A PRELID1P1 PSRC1 RASIP1 RP11-332H18.4 RP11-373D23.3 RP11-613D13.5 SH2B3 SHISA4 SLC35F6 SNRPC STAG3L1 TCTA TMBIM1 ULK3 UPF3A USP36 VKORC1
Pulse rate, automated reading 1.77 14 7 21.2 -0.12 6.4e-01 AC074117.10 ACP2 C11orf1 FNBP4 GOSR2 GPN1 GTF3C2 MET NEGR1 NR1H3 NRBP1 PVRIG SNRPC TCTA
Alcohol intake frequency. 2.25 13 9 27.3 -0.66 5.0e-03 AC074117.10 C18orf8 FNBP4 GPN1 GTF3C2 NCF1B NRBP1 PDXDC2P PMS2P5 RASIP1 RGS12 TCTA VKORC1
Comparative height size at age 10 1.81 41 22 66.7 0.41 6.3e-03 AC003029.1 AC004041.2 AC074117.10 APOPT1 C18orf8 CENPW CTD-2349P21.5 DBN1 DCAF16 DDX42 FTSJ3 GATAD1 GLYR1 GPN1 GTF2B GTF3C2 HEY2 HIVEP3 HOXB7 KIAA1199 NCF1B NCOA1 NFKBIA NRBP1 NUCB2 NUFIP2 PIGV PRELID1P1 PSMC5 RASIP1 RP11-332H18.4 RP11-613D13.5 RP11-810M2.2 RP4-635E18.7 RYK SH2B3 TMBIM1 TSC2 UPF3A USP36 ZFP36L2
Number of full sisters 1.18 1 0 0.0 0.00 1.0e+00 NRBF2
Overall health rating 2.08 10 3 9.1 -1.00 1.8e-09 APOPT1 CEP68 CTSW HIVEP3 PDIA2 PMS2P5 SIPA1 SNRPC TSPY26P VKORC1
Chest pain or discomfort 1.45 1 0 0.0 0.00 1.0e+00 USP36
Qualifications: NVQ or HND or HNC or equivalent 1.47 1 0 0.0 0.00 1.0e+00 AC003029.1
Medication: Aspirin 3.28 6 2 6.1 -0.96 2.2e-03 FES OPRL1 PSRC1 RP11-463M16.4 SERTAD4 SLC22A1
Hypertension (Self-reported) 10.04 168 115 348.5 -0.99 1.9e-149 ABCF3 ABCG5 AC002558.1 AC003029.1 AC006111.1 AC006547.14 ACE ACP2 ACTRT3 ADAM1A AGT AGTRAP AKR1B1 AP3M1 APOPT1 AQP5 ARHGAP42 ARID3B ATG7 ATP2B1 C11orf1 C11orf49 C1GALT1 C20orf160 C4orf22 CCDC112 CD164L2 CENPW CEP41 CEP68 CERS5 CFDP1 CHDH CHP1 CISD2 CLCN6 CLIC4 COX5A CSK CTB-31O20.6 CTC-228N24.3 CTD-2260A17.1 CTD-3032J10.3 CTSW CWF19L2 CYP11A1 DBN1 DBR1 DCAF16 ENPEP EXOC4 FBF1 FBXO41 FES FLJ13197 FNBP4 GLTP GLYR1 GMEB2 GOSR2 GTF2B HEY2 HIBADH HRCT1 IRAK1BP1 JARID2 KB-1107E3.1 KIAA1199 KREMEN1 LDB3 LFNG LOC338758 LSMD1 MAP2K5 MARCH2 MECR MET MOBP MPI MRPL55 MRPS18AP1 MYO9B NAA25 NADK NCOA1 NDUFAF6 NEGR1 NME6 NMT1 NOC3L NPPA NPPA-AS1 NR1H3 NRBF2 NSUN6 NT5C2 NUCB2 OLA1 OPRL1 PAQR5 PCCB PCNX PDE1A PDIA2 PDXK PIGV PLCB1 PLEKHM2 PMS2P5 PRELID1P1 PTPRJ PVRIG RASIP1 RGS19 RNF34 RP11-1055B8.4 RP11-332H18.4 RP11-373D23.3 RP11-463M16.4 RP11-538P18.2 RP11-588K22.2 RP11-613D13.5 RP11-810M2.2 RP3-462E2.5 RP4-635E18.7 RP5-1115A15.1 RPP25 RYK SAV1 SDAD1P1 SDCCAG8 SENP1 SF3B3 SH2B3 SHISA4 SIPA1 SLC22A1 SLC26A10 SLC26A6 SLC35F6 SLC4A7 SMARCE1 SNX16 SPATA33 STAG3L1 SWAP70 TBC1D12 TBC1D19 TCEA2 TH1L THAP9-AS1 THEM6 TMEM116 TMEM57 TNFRSF25 TNNT3 TSC2 TSPY26P UBL3 ULK3 UPF3A VANGL1 VEGFB VKORC1 WNT2B YEATS4 ZBTB46 ZNF318
Illnesses of father: Heart disease 2.37 7 2 6.1 -0.99 8.8e-06 ABCG5 EPOR FES LPL NPC1L1 PSRC1 SLC22A1
Smoking status: Previous 1.43 5 0 0.0 -0.68 2.0e-01 AC003029.1 C18orf8 MAP2K5 SH2B3 TMEM116
Forced expiratory volume in 1-second (FEV1), predicted 1.32 3 1 3.0 0.00 1.0e+00 CTD-2349P21.5 DCAF16 RP11-332H18.4
Whole body fat-free mass 2.06 46 33 100.0 0.23 1.1e-01 AC006547.14 AC074117.10 C18orf8 CCDC112 CENPW CTC-228N24.3 CTD-2349P21.5 DBN1 DCAF16 DDX42 EPOR GATAD1 GLYR1 GPN1 GTF3C2 HEY2 HIVEP3 KIAA1199 MAP2K5 MARCH2 MET MYO9B NCF1B NEGR1 NFKBIA NRBP1 NT5C2 PDE1A PRELID1P1 PSRC1 PTPRJ RP11-332H18.4 RP11-373D23.3 RP11-613D13.5 SH2B3 SHISA4 SLC35F6 SLC4A7 SNRPC STAG3L1 TBC1D12 TMBIM1 ULK3 UPF3A USP36 VKORC1
Leg fat-free mass (right) 1.91 39 30 90.9 0.14 3.9e-01 ABCF3 AC006547.14 AC074117.10 C18orf8 CENPW CLIC4 CTC-228N24.3 CTD-2349P21.5 DBN1 DCAF16 FES GATAD1 GLYR1 GPN1 GTF3C2 HEY2 HIVEP3 KIAA1199 MAP2K5 MYO9B NCF1B NEGR1 NFKBIA NRBP1 NT5C2 PDE1A PRELID1P1 PTPRJ RP11-332H18.4 RP11-613D13.5 SHISA4 SLC35F6 SNRPC STAG3L1 TBC1D12 ULK3 UPF3A USP36 VKORC1
Arm fat percentage (left) 2.00 30 20 60.6 -0.81 6.0e-08 ACP2 APOPT1 C11orf49 C18orf8 CHP1 COX5A CTB-31O20.6 CTSW DCAF16 FBF1 FNBP4 HIVEP3 MAP2K5 NEGR1 NUFIP2 OLA1 PDIA2 PDXDC2P PMS2P5 RNF34 RP11-332H18.4 RP11-613D13.5 RP5-1115A15.1 SHISA4 SIPA1 SNRPC STAG3L1 TCTA TNFRSF25 VKORC1
Average weekly red wine intake 1.47 2 1 3.0 0.00 1.0e+00 C18orf8 MPI
Mood swings 1.30 2 1 3.0 0.00 1.0e+00 ACP2 NR1H3
Loneliness, isolation 1.32 1 0 0.0 0.00 1.0e+00 PTPRJ
Long-standing illness, disability or infirmity 1.85 2 0 0.0 0.00 1.0e+00 CHP1 NEGR1
Diabetes diagnosed by doctor 2.63 11 5 15.2 -0.29 3.2e-01 AC074117.10 ACE CTSW DBR1 GTF3C2 NRBP1 PDXDC2P PMS2P5 SLC22A1 TCTA ZBTB46
Friendships satisfaction 1.08 1 0 0.0 0.00 1.0e+00 C18orf8
Qualifications: nursing, teaching 1.25 1 1 3.0 0.00 1.0e+00 NEGR1
Medication for cholesterol 5.52 19 5 15.2 0.98 5.7e-13 AGT ARHGAP42 ATG7 C4orf22 CENPW DOCK7 JARID2 PIGV PLCB1 PRELID1P1 PSRC1 RASIP1 RGS19 SENP1 SH2B3 SPATA33 TNNT3 WNT2B ZBTB46
Mineral and other dietary supplements 1.18 2 0 0.0 0.00 1.0e+00 NMT1 NRBF2
Breast cancer (self-reported) 1.01 1 1 3.0 0.00 1.0e+00 SLC4A7
Asthma (self-reported) 1.38 4 3 9.1 -0.96 4.0e-02 AC004041.2 FBF1 NMT1 RP5-1115A15.1
Osteoarthritis (self-reported) 1.40 2 0 0.0 0.00 1.0e+00 COX5A RPP25
Medication: Aspirin 3.29 6 2 6.1 -0.98 9.2e-04 FES OPRL1 PSRC1 RP11-463M16.4 SLC22A1 VEGFB
Illnesses of father: None of the above (group 1) 2.51 3 1 3.0 0.00 1.0e+00 ABCG5 FES SH2B3
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.17 3 1 3.0 0.00 1.0e+00 NRBF2 RP11-538P18.2 VKORC1
Whole body water mass 2.06 46 32 97.0 0.24 9.2e-02 AC006547.14 AC074117.10 C18orf8 CCDC112 CENPW CTC-228N24.3 CTD-2349P21.5 DBN1 DCAF16 DDX42 EPOR GATAD1 GLYR1 GPN1 GTF3C2 HEY2 HIVEP3 KIAA1199 MAP2K5 MARCH2 MET MYO9B NCF1B NEGR1 NFKBIA NMT1 NRBP1 NT5C2 PDE1A PRELID1P1 PSRC1 PTPRJ RP11-332H18.4 RP11-373D23.3 RP11-613D13.5 SH2B3 SHISA4 SLC35F6 SNRPC STAG3L1 TBC1D12 TMBIM1 ULK3 UPF3A USP36 VKORC1
Leg predicted mass (right) 1.91 39 30 90.9 0.14 3.9e-01 ABCF3 AC006547.14 AC074117.10 C18orf8 CENPW CLIC4 CTC-228N24.3 CTD-2349P21.5 DBN1 DCAF16 FES GATAD1 GLYR1 GPN1 GTF3C2 HEY2 HIVEP3 KIAA1199 MAP2K5 MYO9B NCF1B NEGR1 NFKBIA NRBP1 NT5C2 PDE1A PRELID1P1 PTPRJ RP11-332H18.4 RP11-613D13.5 SHISA4 SLC35F6 SNRPC STAG3L1 TBC1D12 ULK3 UPF3A USP36 VKORC1
Arm fat mass (left) 2.00 32 16 48.5 -0.69 1.2e-05 ACP2 APOPT1 C11orf49 C18orf8 COX5A CTB-31O20.6 CTSW FBF1 FNBP4 HEY2 HIVEP3 HPR KIAA1199 MAP2K5 NEGR1 NT5C2 OLA1 PDIA2 PDXDC2P PMS2P5 RP11-613D13.5 RP11-810M2.2 RP5-1115A15.1 RPP25 SF3B3 SHISA4 SNRPC STAG3L1 TCTA TNFRSF25 USP36 VKORC1
Number of self-reported non-cancer illnesses 4.36 18 2 6.1 -0.98 2.8e-12 AC003029.1 AC074117.10 APOPT1 CISD2 CPEB2 FBXO41 GMEB2 GPN1 LSMD1 MYO9B NEGR1 OPRL1 PMS2P5 RGS19 SH2B3 SLC22A1 TCEA2 ZNF318
Miserableness 1.16 4 1 3.0 -0.80 2.0e-01 ACP2 FNBP4 NR1H3 RP5-1115A15.1
Guilty feelings 1.09 1 0 0.0 0.00 1.0e+00 FNBP4
Medication: Blood pressure 7.35 67 33 100.0 -0.98 1.5e-52 AC003029.1 AC006111.1 ACE ACP2 ACTRT3 AGT AP3M1 AQP5 ARHGAP42 ARID3B ATG7 C11orf1 C1GALT1 C4orf22 CENPW CERS5 CHP1 CLCN6 COX5A CSK CTD-3032J10.3 CTSW CWF19L2 CYP11A1 DBR1 FES GMEB2 GTF2B HRCT1 KB-1107E3.1 KIAA1199 LFNG LSMD1 MPI MYO9B NCOA1 NME6 NPPA NR1H3 NRBF2 NT5C2 OPRL1 PDXK PIGV PLCB1 PRELID1P1 RNF34 RP11-1055B8.4 RP11-588K22.2 RP11-810M2.2 RP4-635E18.7 RPP25 SH2B3 SIPA1 SLC26A6 SLC35F6 SLC4A7 SPATA33 TBC1D19 TCEA2 TNNT3 UBL3 ULK3 VEGFB WNT2B ZBTB46 ZNF318
High cholesterol (Self-reported) 8.48 36 27 81.8 -0.91 5.8e-16 ABCG5 AC002558.1 AC074117.10 APOB ARHGAP42 BCAM DCAF16 DOCK7 EPOR FBF1 GPN1 GTF3C2 HPR LPL MET NCF1B NPC1L1 NPEPPS NRBP1 OPRL1 PAFAH1B2 PIGV PSRC1 PVRL2 RASIP1 RGL3 RGS19 RPS6 SLC22A1 TCEA2 TIMD4 TMBIM1 TOMM40 VEGFB VKORC1 ZNF259
Medication: Bendroflumethiazide 4.59 19 8 24.2 -0.97 1.4e-11 ABCF3 ACP2 ARHGAP42 ATP2B1 CCDC112 CD164L2 CSK FES FNBP4 KIAA1199 MYO9B NR1H3 PIGV PLCB1 PRELID1P1 SLC35F6 SLC4A7 TNNT3 WNT2B
Medication: Paracetamol 1.51 2 0 0.0 0.00 1.0e+00 NMT1 SDCCAG8
Medication: Lisinopril 3.30 4 0 0.0 -0.97 2.8e-02 ARHGAP42 NME6 NRBF2 SLC26A6
Medication: Atorvastatin 4.02 12 9 27.3 -0.99 6.9e-11 AC074117.10 APOB EPOR GPN1 GTF3C2 NRBP1 PAFAH1B2 PSRC1 SLC22A1 TOMM40 VKORC1 ZNF259
Illnesses of father: High blood pressure 3.26 8 1 3.0 -0.98 2.3e-05 ACE C4orf22 FES NCOA1 NR1H3 PLCB1 SPATA33 UPF3A
Ever smoked 1.24 1 0 0.0 0.00 1.0e+00 C18orf8
Basal metabolic rate 2.02 43 30 90.9 0.06 6.9e-01 AC006547.14 AC074117.10 C18orf8 CCDC112 CENPW CTC-228N24.3 CTD-2349P21.5 CTSW DBN1 DCAF16 EPOR GATAD1 GLYR1 GPN1 GTF3C2 HEY2 HIVEP3 KIAA1199 MAP2K5 MARCH2 MET NCF1B NEGR1 NFKBIA NRBP1 NT5C2 PDE1A PRELID1P1 PTPRJ RP11-332H18.4 RP11-373D23.3 RP11-613D13.5 SH2B3 SHISA4 SLC35F6 SNRPC STAG3L1 TCTA TMBIM1 ULK3 UPF3A USP36 VKORC1
Leg fat percentage (left) 2.24 34 18 54.5 -0.86 6.0e-11 ACP2 APOPT1 C11orf49 C18orf8 CHP1 COX5A CRK CTB-31O20.6 CTC-228N24.3 CTSW DCAF16 GTF2B HIVEP3 MAP2K5 MOBP NEGR1 NMT1 NUFIP2 PDIA2 PDXDC2P PMS2P5 RP11-613D13.5 RP11-810M2.2 RP5-1115A15.1 RPP25 SERTAD4 SHISA4 SIPA1 SNRPC STAG3L1 TBC1D12 TCTA TNFRSF25 VKORC1
Arm fat-free mass (left) 2.10 41 28 84.8 0.09 5.5e-01 AC006547.14 AC074117.10 C18orf8 CENPW CTD-2349P21.5 CTSW DCAF16 EPOR GATAD1 GLYR1 GPN1 GTF3C2 HEY2 HIVEP3 KIAA1199 MAP2K5 MARCH2 MET NCF1B NEGR1 NFKBIA NRBP1 NT5C2 PDE1A PRELID1P1 PTPRJ RASIP1 RP11-332H18.4 RP11-373D23.3 RP11-613D13.5 SH2B3 SHISA4 SLC35F6 SNRPC STAG3L1 TCTA TMBIM1 ULK3 UPF3A USP36 VKORC1
Number of operations (self-reported) 1.42 1 0 0.0 0.00 1.0e+00 ZCCHC10
Average weekly beer plus cider intake 1.17 2 0 0.0 0.00 1.0e+00 AQP5 CCDC112
Risk taking 1.19 2 0 0.0 0.00 1.0e+00 PCCB SDCCAG8
Diastolic blood pressure, automated reading 5.95 86 52 157.6 -0.97 9.0e-59 AC003029.1 AC006111.1 ACP2 ACTR1B ACTRT3 ADAM1A AGT AGTRAP AQP5 ARHGAP42 ATP2B1 C1GALT1 C20orf160 C4orf22 CENPW CERS5 CHP1 CLCN6 CLIC4 COX5A CSK CTB-31O20.6 CTD-3032J10.3 CTSW CWF19L2 CYP11A1 DCAF16 ENPEP FBLN7 FBXO41 FES FNBP4 GLTP GMEB2 HRCT1 IRAK1BP1 KIAA1199 LFNG LOC338758 LSMD1 MAP2K5 MPI MRPS18AP1 MYO9B NAA25 NCOA1 NDUFAF6 NME6 NMT1 NOC3L NR1H3 NRBF2 NSUN6 NT5C2 OLA1 PDE1A PDIA2 PIGV PMS2P5 PRELID1P1 PVRIG RNASEH2C RP11-332H18.4 RP11-463M16.4 RP11-538P18.2 RP3-462E2.5 RP5-1115A15.1 RPP25 RYK SDCCAG8 SH2B3 SHISA4 SIPA1 SLC26A6 STAG3L1 SWAP70 TCEA2 TCTA THEM6 TMEM116 TNNT3 ULK3 UPF3A USP36 VKORC1 WNT2B
Vascular/heart problems diagnosed by doctor 9.89 162 106 321.2 0.99 2.0e-148 ABCG5 AC002558.1 AC003029.1 AC006111.1 AC006547.14 ACE ACP2 ACTR1B ACTRT3 ADAM1A AGT AGTRAP AKR1B1 AP3M1 APOPT1 AQP5 ARHGAP42 ARID3B ATG7 ATP2B1 C11orf1 C11orf49 C1GALT1 C20orf160 C4orf22 CCDC112 CD164L2 CENPW CEP41 CEP68 CERS5 CFDP1 CHP1 CIRH1A CISD2 CLCN6 COX5A CPEB2 CRK CSK CTB-31O20.6 CTC-228N24.3 CTD-2260A17.1 CTD-3032J10.3 CTSW CWF19L2 CYP11A1 DBR1 DCAF16 ENPEP EXOC4 FBF1 FBXO41 FES FLJ13197 FNBP4 GLTP GLYR1 GMEB2 GTF2B HIBADH HIVEP3 HRCT1 IRAK1BP1 JARID2 KB-1107E3.1 KIAA1199 KREMEN1 LDB3 LFNG LOC338758 LSMD1 MAP2K5 MARCH2 MET MOBP MPI MRPL55 MRPS18AP1 MYO9B NAA25 NADK NCOA1 NDUFAF6 NEGR1 NME6 NMT1 NOC3L NPEPPS NPPA NR1H3 NRBF2 NSUN6 NT5C2 NUCB2 NUFIP2 OLA1 OPRL1 PCCB PDE1A PDIA2 PDXK PIGV PLCB1 PLEKHM2 PMS2P5 PRELID1P1 PTPRJ PVRIG RASIP1 RGS19 RNF34 RP11-1055B8.4 RP11-332H18.4 RP11-463M16.4 RP11-538P18.2 RP11-588K22.2 RP11-613D13.5 RP11-810M2.2 RP1-62O9.3 RP3-462E2.5 RP4-635E18.7 RP5-1115A15.1 RPP25 RYK SAV1 SDAD1P1 SDCCAG8 SENP1 SH2B3 SIPA1 SLC22A1 SLC26A10 SLC26A6 SLC35F6 SLC4A7 SNX16 SPATA33 STAG3L1 SWAP70 TBC1D12 TBC1D19 TCEA2 TCTA TH1L THAP9-AS1 THEM6 TMEM116 TMEM57 TNFRSF25 TNNT3 TSPY26P UBL3 ULK3 VANGL1 VEGFB VKORC1 WNT2B YEATS4 ZBTB46 ZCCHC10 ZNF318
Cholesterol lowering medication 5.33 26 14 42.4 -0.96 6.8e-16 ABCG5 AC074117.10 APOB BCAM DCAF16 DOCK7 EPOR GTF3C2 HPR LPL NPC1L1 NRBP1 NUFIP2 OPRL1 PAFAH1B2 PIGV PSRC1 PVRL2 RASIP1 RGS19 TCEA2 TIMD4 TOMM40 VEGFB VKORC1 ZNF259
Heart attack/myocardial infarction (self-reported) 2.46 4 2 6.1 -0.99 1.1e-02 FES PCCB PSRC1 SH2B3
Heart disease (siblings) 1.92 2 0 0.0 0.00 1.0e+00 FES PVRIG
Impedance of whole body 1.80 43 21 63.6 0.14 3.8e-01 ABCF3 AC006547.14 AC074117.10 CENPW CEP41 CERS5 CISD2 CTB-31O20.6 CTC-228N24.3 CTD-3032J10.3 CTSW CYP11A1 DBN1 EXOC4 GPN1 HEY2 KIAA1199 LOC400043 MAP2K5 MARCH2 MYO9B NADK NCF1B NEGR1 NOC3L NT5C2 PAQR5 PCCB PDE1A PDXDC2P PMS2P5 RP11-463M16.4 RP11-613D13.5 RP1-62O9.3 RYK SENP1 SHISA4 SNRPC STAG3L1 SWAP70 TBC1D12 ULK3 VKORC1
Leg fat mass (left) 2.12 31 17 51.5 -0.81 4.7e-08 ACP2 C18orf8 CTB-31O20.6 CTSW HEY2 HIVEP3 KB-1107E3.1 KIAA1199 MAP2K5 MET NEGR1 NUFIP2 OLA1 PDIA2 PDXDC2P PMS2P5 RP11-613D13.5 RP11-810M2.2 RP5-1115A15.1 RPP25 SF3B3 SHISA4 SNRPC STAG3L1 TCTA TNFRSF25 TSC2 TSPY26P ULK3 USP36 VKORC1
Arm predicted mass (left) 2.12 42 29 87.9 0.13 4.0e-01 AC006547.14 AC074117.10 C18orf8 CENPW CTD-2349P21.5 DCAF16 EPOR GATAD1 GLYR1 GPN1 GTF3C2 HEY2 HIVEP3 KIAA1199 MAP2K5 MARCH2 MET NCF1B NCOA1 NEGR1 NFKBIA NRBP1 NT5C2 PDE1A PRELID1P1 PSRC1 PTPRJ RASIP1 RP11-332H18.4 RP11-373D23.3 RP11-613D13.5 SH2B3 SHISA4 SLC35F6 SNRPC STAG3L1 TCTA TMBIM1 ULK3 UPF3A USP36 VKORC1

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 60 1.718 3.55
GTEx Adipose Visceral Omentum 34 1.669 3.55
GTEx Adrenal Gland 23 1.579 3.38
GTEx Artery Aorta 57 1.915 3.62
GTEx Artery Coronary 22 1.858 3.45
GTEx Artery Tibial 54 1.437 3.61
GTEx Brain Caudate basal ganglia 13 1.413 3.22
GTEx Brain Cerebellar Hemisphere 28 1.880 3.48
GTEx Brain Cerebellum 34 1.715 3.64
GTEx Brain Cortex 23 2.224 3.63
GTEx Brain Frontal Cortex BA9 20 2.162 3.58
GTEx Brain Hippocampus 8 1.524 3.25
GTEx Brain Hypothalamus 6 1.015 2.97
GTEx Brain Nucleus accumbens basal ganglia 14 1.617 3.50
GTEx Brain Putamen basal ganglia 5 0.801 3.07
GTEx Breast Mammary Tissue 35 1.772 3.38
GTEx Breast Mammary Tissue (Male) 20 1.676 3.31
GTEx Breast Mammary Tissue (Female) 20 1.216 3.25
GTEx Cells EBV-transformed lymphocytes 20 1.407 3.41
GTEx Cells Transformed fibroblasts 61 1.453 3.40
GTEx Colon Sigmoid 22 1.504 3.38
GTEx Colon Transverse 37 1.792 3.42
GTEx Esophagus Gastroesophageal Junction 29 2.007 3.55
GTEx Esophagus Mucosa 53 1.596 3.48
GTEx Esophagus Muscularis 53 1.640 3.50
GTEx Heart Atrial Appendage 19 1.203 3.19
GTEx Heart Left Ventricle 25 1.633 3.41
GTEx Liver 13 1.813 3.35
GTEx Lung 45 1.566 3.49
GTEx Muscle Skeletal 46 1.591 3.48
GTEx Nerve Tibial 68 1.573 3.23
GTEx Ovary 24 2.640 3.74
GTEx Pancreas 23 1.408 3.41
GTEx Pituitary 18 1.613 3.45
GTEx Prostate 20 2.398 3.59
GTEx Skin Not Sun Exposed Suprapubic 43 1.748 3.50
GTEx Skin Sun Exposed Lower leg 64 1.760 3.52
GTEx Small Intestine Terminal Ileum 4 0.866 3.47
GTEx Spleen 16 1.134 3.34
GTEx Stomach 31 2.131 3.79
GTEx Testis 63 1.996 3.44
GTEx Thyroid 70 1.751 3.47
GTEx Uterus 9 1.587 3.09
GTEx Vagina 10 1.575 3.48
GTEx Whole Blood 31 1.558 3.39
METSIM Adipose 57 1.238 3.09
NTR Blood 31 1.291 3.11
ROSMAP Brain Pre-frontal Cortex 62 1.412 3.37
YFS Blood 51 1.105 3.11
CommonMind Brain Pre-frontal Cortex 68 1.265 3.12
TCGA Breast Tumor 15 1.958 3.35
TCGA Breast Normal 64 1.521 3.09
TCGA Ovarian Tumor 22 0.753 2.71
TCGA Prostate Tumor 52 1.504 3.11