Hub : Traits :

Lung FVC

3792 significantly associated models · 970 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 838555 2573199 5 2 4.8e-12 4.8e-17 1.3e-14 16 CALML6 RP1-283E3.4
2 1 7314655 8738937 1 1 2.8e-09 1.4e-09 1.8e-01 95 PARK7
3 1 15651062 18132937 21 2 8.6e-24 2.2e-22 5.1e-02 96 CLCNKA MST1P2
4 1 22080775 23545787 1 1 2.0e-07 7.2e-13 7.1e-13 0 ZBTB40
5 1 25695835 27595862 5 2 2.4e-08 2.8e-08 1.0e+00 100 DHDDS PDIK1L
6 1 40799427 42542658 2 1 1.2e-08 8.4e-07 6.3e-03 69 SCMH1
7 1 77464831 79041520 2 1 5.4e-10 2.6e-09 2.9e-01 97 USP33
8 1 86635245 88077288 1 1 3.6e-07 4.3e-07 3.0e-01 96 SEP15
9 1 112312154 113941737 5 1 1.9e-10 9.7e-09 2.0e-03 71 ST7L
10 1 114893146 116330558 1 1 1.2e-08 1.4e-09 6.2e-03 80 TSPAN2
11 1 149672809 151929022 30 7 1.2e-31 3.6e-28 NaN NaN CA14 CERS2 CTSS MRPS21 RP11-316M1.12 RP11-458I7.1 RPRD2
12 1 153241677 155910830 7 2 2.6e-13 1.9e-13 1.0e+00 100 MUC1 RP11-422P24.10
13 1 178129899 179534540 1 1 9.3e-08 7.2e-10 1.8e-03 74 ANGPTL1
14 1 182744205 184266571 1 1 1.4e-08 3.7e-07 5.1e-01 98 SMG7
15 1 195927451 197488569 3 1 4.2e-11 2.4e-11 4.4e-03 82 CFHR3
16 1 203692179 206329620 5 3 1.0e-15 5.0e-14 3.8e-03 85 LRRN2 MDM4 RAB7L1
17 1 206802184 208231688 1 1 1.1e-09 4.1e-09 2.0e-01 95 CD55
18 1 209706685 211105395 1 1 3.9e-08 1.7e-11 8.8e-06 56 C1orf133
19 1 217760821 219208920 1 1 2.6e-11 4.5e-19 2.2e-18 4 RRP15
20 1 220171786 221753645 5 3 6.4e-20 8.9e-30 6.8e-16 49 C1orf115 HLX
21 1 223846564 225265424 1 1 4.0e-09 5.7e-09 1.0e+00 100 CNIH4
22 2 23453834 25083310 3 1 2.2e-14 7.6e-14 1.5e-01 96 UBXN2A
23 2 32483593 34319972 1 1 7.2e-09 3.2e-12 2.7e-05 64 LTBP1
24 2 35884899 37472804 1 1 4.0e-07 1.9e-08 5.4e-06 35 CRIM1
25 2 47224927 49519654 6 6 2.8e-15 1.9e-14 NaN NaN MSH6 PPP1R21 RP11-191L17.1 STON1
26 2 54817683 56843605 2 2 5.6e-28 6.3e-36 9.4e-06 88 CCDC88A EFEMP1
27 2 60677772 62069528 1 1 1.9e-08 3.7e-08 1.6e-01 93 AC016747.3
28 2 68850921 71228388 6 2 2.0e-14 6.2e-18 1.3e-08 56 FAM136A GFPT1
29 2 88239332 89130009 4 1 1.6e-13 2.3e-13 1.0e+00 100 AC062029.1
30 2 100193898 101629737 1 1 1.8e-08 3.1e-09 3.8e-02 88 LONRF2
31 2 134513621 137435625 7 5 4.3e-17 8.7e-16 NaN NaN CCNT2 DARS MCM6
32 2 156594333 158165818 1 1 2.0e-07 8.7e-10 4.5e-05 56 GPD2
33 2 177451264 180139951 7 2 7.4e-21 1.9e-20 8.3e-01 100 AC073834.3 RP11-171I2.2
34 2 190583187 192712723 3 2 3.3e-08 6.2e-09 2.4e-02 85 STAT4 TMEM194B
35 2 202434393 204549680 2 2 8.7e-10 3.2e-10 6.5e-03 81 CARF NOP58
36 2 209599808 211264173 1 1 5.0e-20 4.3e-20 1.0e+00 100 MAP2
37 2 217456567 219846749 3 3 6.4e-08 3.8e-19 9.1e-15 25 DIRC3 RP11-378A13.1 TMBIM1
38 2 224636490 226142508 1 1 1.4e-15 9.1e-09 7.9e-01 100 CUL3
39 2 226980411 228725864 3 1 2.2e-08 9.8e-09 1.0e+00 100 RHBDD1
40 2 231564626 234145080 3 3 5.0e-08 6.0e-08 4.0e-01 98 B3GNT7 COPS7B EIF4E2
41 2 238531976 239996179 1 1 2.5e-08 3.0e-12 1.8e-05 62 TRAF3IP1
42 2 241133660 243048760 5 2 1.7e-23 3.5e-22 3.6e-01 99 BOK C2orf54
43 3 8123440 9674325 1 1 4.2e-08 3.5e-09 6.9e-04 67 RAD18
44 3 11829474 13274240 1 1 1.6e-07 2.9e-10 1.1e-06 40 TSEN2
45 3 32339493 33950934 2 2 5.6e-11 8.8e-23 3.1e-19 17 GLB1 SUSD5
46 3 48702606 51398958 16 3 6.9e-13 2.6e-09 4.9e-05 54 RNF123 SEMA3B-AS1
47 3 56629678 58613378 3 1 3.9e-12 4.7e-11 4.2e-04 71 PDE12
48 3 71029408 72501994 1 1 3.9e-11 1.1e-20 4.3e-11 50 EIF4E3
49 3 87495550 90228124 2 2 2.5e-07 5.9e-07 1.0e+00 100 EPHA3 ZNF654
50 3 97736804 101160339 4 3 6.0e-13 7.6e-35 1.9e-23 34 CMSS1 ST3GAL6-AS1 TFG
51 3 121387784 122828990 2 1 1.6e-08 2.1e-08 1.0e+00 100 CCDC58
52 3 126009008 127452273 1 1 1.0e-07 2.0e-07 4.2e-01 98 PLXNA1
53 3 133088362 135671866 5 1 1.5e-17 1.4e-16 3.6e-01 99 CEP63
54 3 137087787 139050702 3 1 1.4e-09 8.4e-10 1.0e+00 100 MRAS
55 3 140350567 141867638 1 1 2.4e-11 1.6e-11 1.0e+00 100 ZBTB38
56 3 148988153 150461933 1 1 7.7e-09 8.1e-07 5.7e-06 16 PFN2
57 3 157125828 159140638 6 1 1.9e-32 2.4e-27 3.0e-01 99 RP11-538P18.2
58 3 195279119 197724684 5 4 2.7e-11 1.8e-16 1.8e-01 97 DLG1 NCBP2-AS2 PCYT1A
59 4 2233366 4219590 5 3 1.1e-14 3.8e-13 1.0e+00 100 GRK4 LRPAP1
60 4 4316736 5717867 1 1 9.1e-08 3.0e-09 1.5e-04 59 CYTL1
61 4 7887500 10749071 2 2 4.7e-08 2.2e-08 1.0e-01 91 CPZ SLC2A9
62 4 17104059 18507692 1 1 8.9e-15 2.2e-10 1.9e-01 96 DCAF16
63 4 53557678 55018996 1 1 1.1e-07 6.4e-08 1.0e+00 100 FIP1L1
64 4 57080198 58674284 4 2 3.4e-09 1.3e-08 1.0e+00 100 IGFBP7 NOA1
65 4 76539958 78402379 2 1 1.0e-09 2.2e-09 1.3e-01 94 SHROOM3
66 4 87165758 88859131 2 1 3.1e-10 2.3e-11 2.3e-02 88 AFF1
67 4 89335667 90734728 1 2 3.3e-11 5.6e-19 9.1e-09 58 TIGD2
68 4 99528449 100942337 1 1 1.9e-08 8.9e-10 2.7e-05 53 ADH1B
69 4 105373669 107622327 5 1 2.7e-39 1.7e-39 1.0e+00 100 INTS12
70 4 123124327 124538705 1 1 3.2e-07 1.0e-10 7.1e-05 62 NUDT6
71 4 127856015 129581793 3 1 2.7e-09 2.9e-11 2.4e-03 79 INTU
72 4 145203531 146706624 1 1 4.4e-08 1.1e-28 1.6e-31 -10 ANAPC10
73 4 150316563 151871473 1 1 5.6e-08 2.1e-10 2.6e-04 67 DCLK2
74 4 165595556 167114948 1 1 9.5e-12 6.8e-12 1.0e+00 100 CPE
75 4 169317081 170886793 1 1 3.7e-08 8.3e-08 7.2e-02 89 SH3RF1
76 5 42321011 44403631 7 3 5.7e-14 1.6e-20 5.2e-14 34 CTD-2201E18.3 NNT PAIP1
77 5 51592336 53083975 1 1 7.1e-10 7.5e-14 8.8e-06 65 ITGA2
78 5 60983430 62394367 1 1 3.2e-08 7.4e-13 2.1e-06 56 DIMT1
79 5 63390398 65013703 1 1 1.4e-07 1.6e-09 1.3e-05 48 CWC27
80 5 67818581 68828296 1 1 4.8e-08 4.3e-09 3.6e-04 63 MRPS36
81 5 77597974 79318982 3 1 4.2e-10 9.7e-11 1.0e+00 100 JMY
82 5 92051598 93624507 2 1 6.4e-11 1.1e-10 1.4e-01 95 NR2F1
83 5 117907292 119434193 1 1 6.5e-08 1.7e-09 6.7e-03 80 TNFAIP8
84 5 121480516 123449266 5 2 5.7e-12 2.1e-13 6.3e-04 78 CEP120 CTB-36H16.2
85 5 126587995 128220643 3 5 1.2e-13 1.2e-11 1.0e+00 100 CTC-228N24.3 SLC12A2
86 5 129797129 133140038 12 8 1.5e-19 4.2e-17 NaN NaN AC034220.3 HINT1 HSPA4 P4HA2 SLC22A5
87 5 138933151 140784895 7 1 1.9e-09 3.0e-07 2.1e-01 94 ZMAT2
88 5 141958831 143510824 1 1 5.4e-08 1.7e-13 4.5e-07 53 NR3C1
89 5 147063674 150635429 6 3 1.2e-17 1.7e-15 7.2e-01 100 ABLIM3 HTR4 NDST1
90 6 925581 2945331 1 1 9.5e-09 2.7e-12 7.0e-13 -5 GMDS
91 6 6701209 8278455 2 2 5.0e-10 2.5e-39 6.2e-37 6 DSP RIOK1
92 6 33856903 36581149 10 2 7.3e-14 2.9e-10 1.1e-11 -16 C6orf106 TCP11
93 6 44079216 46083971 2 2 9.7e-09 2.1e-11 1.2e-04 67 RP1-244F24.1 SUPT3H
94 6 55222696 56954550 1 1 1.0e-09 1.5e-12 1.4e-06 53 COL21A1
95 6 75612601 77324522 2 2 7.8e-11 6.2e-11 2.3e-03 78 MYO6 SENP6
96 6 80120201 81763771 2 1 1.8e-11 3.0e-10 4.1e-01 98 RP11-250B2.6
97 6 99324687 100719911 1 1 5.6e-08 1.4e-06 9.0e-01 100 RP1-199J3.5
98 6 104478130 106230491 2 1 3.2e-16 9.3e-17 1.0e+00 100 LIN28B
99 6 108183628 110710018 4 2 1.1e-07 6.3e-08 1.1e-01 92 FOXO3 SMPD2
100 6 125970401 127355237 1 1 1.3e-16 5.0e-19 2.8e-07 67 CENPW
101 6 130464889 132080991 1 1 1.5e-10 6.9e-11 1.4e-01 95 EPB41L2
102 6 133575570 136727603 4 2 1.9e-12 1.8e-14 5.6e-03 87 AHI1 TBPL1
103 6 143565218 145078694 1 1 3.4e-09 6.2e-11 4.5e-10 9 PLAGL1
104 6 154487421 156330580 3 1 2.0e-11 5.2e-11 3.7e-02 90 RP11-477D19.2
105 6 157713662 159884002 3 2 9.8e-13 1.2e-13 3.8e-02 92 MIR3918 TULP4
106 6 168923561 170822057 4 3 8.7e-12 1.6e-17 1.2e-08 55 PHF10 RP1-137D17.1 XXyac-YX65C7_A.2
107 7 1161158 2972072 1 1 1.6e-08 3.1e-08 7.8e-03 77 MAD1L1
108 7 5359680 7988091 4 3 9.4e-09 4.3e-08 1.0e-05 35 AC079742.4 AIMP2 C1GALT1
109 7 17133294 19854141 2 3 4.0e-11 9.8e-16 2.0e-10 37 SNX13 TWIST1
110 7 22946782 24382726 1 1 1.8e-08 1.4e-16 4.1e-14 16 CCDC126
111 7 25715984 27880888 4 2 1.5e-11 4.7e-12 1.5e-16 -43 AC004540.4 SKAP2
112 7 64498257 66931015 3 1 3.7e-09 3.9e-07 1.2e-01 91 VKORC1L1
113 7 104060000 105606983 1 1 3.2e-09 1.5e-08 4.1e-03 74 SRPK2
114 7 137446778 138952700 1 1 3.1e-07 3.6e-09 6.4e-04 67 TRIM24
115 7 139700516 141413051 5 3 2.3e-15 2.0e-15 1.0e+00 100 BRAF MRPS33 NDUFB2-AS1
116 7 149847287 151474607 4 3 5.8e-09 2.1e-08 4.5e-01 98 ABCB8 AOC1 CDK5
117 8 20853274 23240950 9 3 4.2e-11 4.3e-11 1.0e+00 100 BIN3 GFRA2 POLR3D
118 8 32670264 34065815 1 1 1.2e-09 1.8e-08 5.9e-05 49 TTI2
119 8 37329315 39836128 4 2 1.3e-08 6.0e-07 2.2e-02 79 ADAM32 RP11-90P5.2
120 8 48221724 49584958 1 1 1.3e-10 4.1e-12 2.3e-05 63 MCM4
121 8 56094665 57683880 2 1 1.5e-13 6.9e-14 6.2e-02 94 RPS20
122 8 60903659 62477554 1 1 5.3e-08 5.7e-10 1.0e+00 100 CHD7
123 8 85591518 87083747 3 1 2.5e-12 5.3e-13 5.5e-02 93 RP11-317J10.2
124 8 109213088 110765282 1 1 2.0e-08 2.8e-09 2.5e-04 62 RP11-1084E5.1
125 8 144465285 146293414 22 9 1.2e-20 4.4e-23 1.0e+00 100 BOP1 CTD-3232M19.2 GS1-393G12.12 HSF1 KIAA1875 KIFC2 KM-PA-2 NFKBIL2 TONSL
126 9 14857740 16758776 1 1 1.4e-12 8.4e-12 6.5e-02 93 CCDC171
127 9 85657836 87315117 3 1 1.3e-12 4.4e-12 1.0e-01 94 RMI1
128 9 94363366 96126104 5 1 8.7e-12 1.0e-10 1.0e-02 84 NOL8
129 9 97520168 98975128 2 1 2.6e-28 1.1e-32 4.5e-06 85 PTCH1
130 9 135521303 137034272 2 1 1.5e-07 7.7e-09 2.9e-03 74 CACFD1
131 9 138403706 140076439 7 2 2.8e-26 1.9e-26 1.0e+00 100 QSOX2 SDCCAG3
132 10 11167624 13569805 4 3 3.7e-13 2.4e-15 1.0e-01 96 CAMK1D CDC123 PROSER2
133 10 21087485 22724472 2 1 1.5e-09 7.9e-11 1.6e-02 86 MLLT10
134 10 30411253 32916171 2 2 2.1e-10 7.7e-09 5.9e-01 99 ARHGAP12 ZNF438
135 10 64195778 65606229 1 1 7.3e-09 6.7e-11 7.0e-04 73 NRBF2
136 10 69293282 70981217 5 2 1.6e-12 6.8e-31 1.3e-16 49 DNA2 PBLD
137 10 73402498 76373904 14 3 1.0e-17 6.5e-18 1.0e+00 100 DNAJB12 RP11-574K11.5 SEC24C
138 10 76664253 79018276 1 1 3.4e-19 1.6e-25 3.1e-08 72 C10orf11
139 10 80443273 81901722 1 1 2.2e-11 3.2e-20 1.4e-13 36 ZCCHC24
140 10 95060188 96779866 1 1 4.6e-09 5.2e-10 1.0e+00 100 PLCE1
141 10 103807817 106371784 3 2 3.7e-10 1.1e-09 1.0e+00 100 RP11-541N10.3 WBP1L
142 10 117949460 119582073 1 1 1.3e-07 1.1e-07 3.1e-01 96 KIAA1598
143 11 11706291 13250399 1 1 4.7e-08 3.3e-18 4.0e-16 12 PARVA
144 11 42881882 45937306 3 2 1.2e-17 7.2e-17 1.0e+00 100 PRDM11 RP11-613D13.5
145 11 60965461 63284510 13 9 1.9e-29 9.5e-29 1.0e+00 100 EEF1G EML3 GANAB MTA2 NXF1 RAB3IL1 ROM1 TTC9C
146 11 64789077 69406625 31 13 3.2e-15 4.0e-16 NaN NaN B3GNT1 CFL1 DPP3 EIF1AD MRPL21 PACS1 PELI3 RIN1 RNASEH2C SF3B2 TBX10
147 11 71769936 73198494 1 1 2.8e-07 3.7e-07 7.6e-03 72 STARD10
148 11 88358544 89943681 1 1 1.1e-07 7.7e-09 6.2e-03 78 NOX4
149 11 116352008 117795942 3 1 1.8e-08 1.7e-08 3.6e-02 86 SIDT2
150 11 118365263 119765318 1 1 1.4e-07 4.6e-06 2.0e-02 74 CCDC153
151 11 127866485 129376495 1 1 1.1e-09 1.8e-12 3.5e-12 3 FLI1
152 11 129575976 130992111 1 1 7.5e-11 1.0e-11 3.2e-03 81 ADAMTS8
153 12 403545 2299048 1 1 8.0e-10 1.4e-16 1.7e-08 53 ERC1
154 12 2489314 4086893 1 1 8.6e-08 3.4e-12 1.4e-14 -22 TSPAN9
155 12 26986748 29432481 6 9 1.5e-71 3.7e-66 1.0e+00 100 CCDC91 MRPS35 RP11-860B13.1 RP11-967K21.1
156 12 30084002 31526510 1 1 3.0e-12 3.7e-14 1.9e-03 83 IPO8
157 12 48039874 49444545 1 1 1.8e-07 5.0e-08 2.6e-03 70 ZNF641
158 12 49556303 51912062 7 2 4.3e-12 1.6e-11 1.0e+00 100 BCDIN3D DIP2B
159 12 55694116 57545756 3 2 8.0e-08 2.4e-07 1.0e+00 100 SPRYD4 SUOX
160 12 64519806 65969015 1 1 1.2e-09 2.3e-15 5.7e-12 24 TBC1D30
161 12 84732189 86337816 1 1 2.2e-08 2.3e-10 2.4e-03 77 LRRIQ1
162 12 101929013 103307835 1 1 5.1e-08 5.8e-13 2.4e-06 57 RN7SL793P
163 12 110233500 111634281 1 1 4.3e-09 2.6e-07 1.0e-02 75 VPS29
164 12 111910219 113517494 1 1 3.7e-07 2.3e-05 2.3e-01 92 HECTD4
165 12 114408276 115813607 1 1 1.3e-09 4.9e-20 1.6e-20 -3 TBX3
166 12 116650803 118162572 1 1 3.9e-07 1.3e-09 8.0e-04 70 FBXW8
167 12 120228544 122037099 6 2 8.5e-15 8.0e-15 8.9e-02 95 ACADS DYNLL1-AS1
168 12 122713991 124715313 11 7 8.6e-12 4.7e-12 NaN NaN ABCB9 CDK2AP1 MPHOSPH9 OGFOD2 SBNO1 SETD8
169 12 132613274 133778796 3 1 1.9e-07 5.5e-06 1.4e-02 71 PGAM5
170 13 49123516 50962458 4 4 1.2e-10 3.7e-09 5.2e-01 99 CDADC1 EBPL SETDB2
171 13 72585542 74288499 2 2 2.2e-07 4.4e-07 1.5e-06 9 MZT1 PIBF1
172 13 100558473 102022883 1 1 2.0e-08 5.7e-07 6.4e-01 99 TMTC4
173 14 53731553 55957996 2 2 2.0e-08 2.1e-09 3.6e-05 52 BMP4 SAMD4A
174 14 58981102 60650086 3 1 5.3e-08 3.8e-08 4.0e-03 73 DAAM1
175 14 60754455 62242523 1 1 6.8e-08 7.2e-10 1.0e+00 100 SLC38A6
176 14 73672831 76593690 5 4 1.8e-10 1.7e-26 1.2e-17 36 ALDH6A1 NPC2 RP11-293M10.6 RP5-1021I20.4
177 14 91738696 94495324 7 3 4.8e-31 1.3e-30 1.0e+00 100 BTBD7 RIN3 RP11-529H20.5
178 15 39530508 42886656 16 6 5.4e-13 1.8e-15 4.0e-07 59 BMF CHP DISP2 EIF2AK4 PAK6 RP11-23P13.7
179 15 50509591 52451884 3 2 1.1e-15 3.1e-11 6.6e-03 83 AP4E1 GLDN
180 15 66797492 69178312 5 5 4.4e-16 3.6e-17 NaN NaN IQCH MAP2K5 PIAS1
181 15 74138822 76613093 4 2 2.3e-08 1.3e-15 2.0e-18 -20 ARID3B CTD-2323K18.1
182 15 78032707 79611011 5 1 1.5e-10 5.3e-12 1.0e-02 86 PSMA4
183 15 82250003 86109582 14 3 2.5e-17 4.0e-13 9.1e-03 87 ALPK3 BTBD1 GOLGA6L9
184 16 86671 5627737 23 8 8.8e-34 8.4e-31 1.0e+00 100 CLUAP1 CORO7 SLC9A3R2 UBN1 WFIKKN1 ZNF200 ZNF205-AS1
185 16 7730365 9438692 2 2 4.4e-10 8.4e-09 1.2e-04 56 METTL22 RP11-568A19.1
186 16 27655848 29595483 14 1 1.2e-11 3.4e-11 8.0e-02 93 EIF3C
187 16 29711343 31957368 22 1 4.8e-17 3.9e-15 1.9e-01 97 STX1B
188 16 66542957 68548595 5 1 2.1e-10 1.8e-09 1.0e+00 100 ATP6V0D1
189 16 68670071 73789190 15 11 9.2e-18 5.3e-26 NaN NaN COG4 IL34 KIAA0174 NFAT5 NOB1 NQO1 SF3B3 VAC14-AS1 ZFHX3
190 16 77358979 79943873 2 1 3.4e-12 1.9e-11 3.1e-10 12 WWOX
191 16 88030355 89544756 4 2 1.5e-08 1.4e-10 4.8e-05 60 PIEZO1 SNAI3-AS1
192 17 1263564 2900882 1 1 1.1e-07 4.7e-08 9.9e-07 20 SMG6
193 17 3371501 4863410 1 1 3.4e-07 1.0e-07 9.6e-02 90 ANKFY1
194 17 6397773 8721285 14 10 1.6e-14 1.3e-14 1.0e+00 100 AC113189.5 CHRNB1 CNTROB DLG4 ZBTB4
195 17 15149905 16908991 6 1 1.3e-08 1.6e-08 5.5e-02 88 ZSWIM7
196 17 17017584 18325085 3 1 8.8e-09 6.8e-09 1.0e-01 92 TOM1L2
197 17 26888725 30380381 9 5 5.4e-13 1.7e-26 NaN NaN CRLF3 NUFIP2 OMG TEFM
198 17 36660684 38783469 10 1 8.7e-17 8.7e-17 1.0e+00 100 PNMT
199 17 41946180 47357969 46 13 1.1e-55 3.0e-53 1.0e+00 100 ARL17B CDK5RAP3 HOXB-AS1 LRRC37A NSF PLCD3 RP11-6N17.10 RP11-6N17.9
200 17 48013115 49468264 1 1 1.8e-07 3.3e-06 4.2e-01 97 ABCC3
201 17 58828402 60172573 2 2 1.4e-16 3.7e-22 4.8e-03 92 RP11-332H18.4
202 17 61221773 63531331 8 2 3.4e-17 1.9e-15 9.8e-01 100 CD79B SMURF2
203 17 72503355 74267010 7 4 3.6e-12 8.0e-12 NaN NaN GGA3 LLGL2 MRPS7
204 17 74438939 76195302 2 2 8.6e-08 3.4e-07 1.0e+00 100 SEC14L1 SEPT9
205 17 78778692 80866427 8 10 1.2e-24 1.8e-26 NaN NaN ACTG1 ASPSCR1 CCDC57 DCXR MYADML2 STRA13
206 18 69836 910635 1 1 3.1e-12 3.7e-12 1.0e+00 100 USP14
207 18 8010444 9532097 2 1 1.5e-11 9.2e-13 3.4e-03 83 SOGA2
208 18 19692435 23204100 5 3 3.3e-10 5.0e-20 5.4e-07 70 C18orf8 RBBP8 RP11-449D8.5
209 18 49172179 51753106 1 1 1.8e-07 8.7e-14 7.4e-09 40 DCC
210 18 52209411 54028036 1 1 2.9e-08 9.5e-12 2.7e-08 33 TCF4
211 19 288246 2923263 3 2 4.6e-11 1.1e-09 3.7e-01 98 DOT1L WDR18
212 19 5169772 6609390 5 1 1.4e-15 1.8e-14 1.0e+00 100 AC104532.4
213 19 9271969 11372077 3 2 4.0e-09 5.6e-10 6.3e-03 81 KRI1 OLFM2
214 19 36113459 37605917 3 1 1.0e-08 1.4e-08 1.0e+00 100 ZFP82
215 19 40259342 41827120 3 1 3.3e-23 1.1e-22 4.0e-02 96 LTBP4
216 19 45416478 47796800 6 3 1.3e-09 3.1e-09 8.7e-01 100 CALM3 EML2 PNMAL1
217 19 51666972 53087879 1 1 1.5e-07 6.6e-06 6.3e-01 99 ZNF577
218 20 9925555 11347455 1 1 3.0e-07 1.2e-08 1.4e-03 68 JAG1
219 20 20407782 22065466 2 1 1.3e-08 2.2e-07 2.8e-02 82 XRN2
220 20 24230055 26307797 7 1 2.1e-11 2.1e-11 1.3e-01 95 PYGB
221 20 29522520 31494382 6 2 4.6e-14 1.8e-13 1.0e+00 100 HM13 PLAGL2
222 20 31884069 35512648 37 9 2.9e-37 1.1e-39 NaN NaN CEP250 ERGIC3 GGT7 GSS MAP1LC3A NCOA6 RALY UQCC
223 20 44824099 46516716 1 2 1.8e-12 9.3e-30 9.6e-20 36 EYA2
224 20 46838455 48603940 3 1 1.2e-09 2.2e-11 1.0e+00 100 ARFGEF2
225 20 61522825 62912463 15 10 1.5e-36 1.9e-36 1.0e+00 100 ARFRP1 CTD-3184A7.4 GMEB2 LIME1 OPRL1 SLC2A4RG STMN3 ZGPAT
226 21 34750338 36786185 2 3 6.7e-12 1.2e-14 1.1e-05 67 CLIC6 MRPS6
227 22 17581838 19203078 1 1 2.0e-16 7.1e-19 2.0e-04 82 MICAL3
228 22 29439201 32296000 8 4 4.7e-15 4.4e-12 5.4e-01 99 CTA-85E5.10 OSM RNF185
229 22 41720697 43459864 2 2 2.9e-09 1.3e-07 2.1e-02 81 SLC25A5P1 Z83851.1

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Alzheimer’s Disease (in father) 1.08 2 0 0.0 0.00 1.0e+00 CARF NNT
Alzheimer’s Disease (including proxy) 1.09 1 1 3.0 0.00 1.0e+00 STX1B
Crohns Disease (2017) 1.85 18 14 42.4 0.89 2.3e-08 AC034220.3 ARFRP1 CTD-3184A7.4 CTSS EIF3C HINT1 LIME1 MUC1 P4HA2 PARK7 RP11-574K11.5 SDCCAG3 SEC24C SLC22A5 STARD10 STMN3 ZBTB38 ZGPAT
Irritable Bowel Disease (IBD) 1.77 21 15 45.5 0.87 5.7e-08 AC016747.3 AC034220.3 ARFRP1 CTD-3184A7.4 CTSS EIF3C GMEB2 HINT1 KM-PA-2 LIME1 MUC1 P4HA2 PARK7 RP11-316M1.12 RP11-378A13.1 SDCCAG3 SLC22A5 SLC2A4RG STARD10 STMN3 ZGPAT
Ulcerative Colitis (UC) 1.33 8 5 15.2 0.81 8.2e-03 AC016747.3 ARFRP1 LIME1 MUC1 PARK7 SDCCAG3 SLC22A5 STMN3
Major Depression (MDD) 1.39 2 0 0.0 0.00 1.0e+00 RNF123 TCF4
Reaction Time 1.29 7 2 6.1 -0.16 7.4e-01 DLG4 FOXO3 HECTD4 KIFC2 RMI1 TOM1L2 WFIKKN1
Verbal and Numeric Reasoning (VNR) 1.41 14 9 27.3 0.32 2.4e-01 ARFGEF2 ARL17B DCAF16 DISP2 EIF3C FOXO3 HSF1 KIFC2 LRRC37A NFKBIL2 RNF123 SLC25A5P1 SUOX ZMAT2
Breast Cancer 1.48 10 6 18.2 0.23 4.7e-01 B3GNT1 CTC-228N24.3 CTD-2323K18.1 LRRC37A MLLT10 MUC1 NSF PARK7 RIN3 ZBTB38
Ovarian Cancer 1.33 5 4 12.1 0.99 4.1e-05 CLIC6 HOXB-AS1 LRRC37A MLLT10 NSF
Prostate Cancer 1.61 3 3 9.1 -0.52 4.8e-01 ARFRP1 MDM4 STMN3
Age at First Birth 1.19 1 1 3.0 0.00 1.0e+00 RNF123
Bipolar Disorder 1.82 2 0 0.0 0.00 1.0e+00 B3GNT1 GGT7
Body Mass Index (BMI) (2010) 1.64 3 2 6.1 0.00 1.0e+00 CDK5RAP3 EIF3C MAP2K5
Coronary Artery Disease (CAD) 1.47 1 1 3.0 0.00 1.0e+00 CARF
Crohns Disease (2012) 1.73 10 8 24.2 -0.96 3.8e-07 AC034220.3 ARFRP1 CTD-3184A7.4 HINT1 LIME1 P4HA2 SDCCAG3 SLC22A5 STMN3 ZGPAT
Mean Putamen Volume 1.17 2 0 0.0 0.00 1.0e+00 HM13 NSF
HDL Cholesterol 1.23 6 3 9.1 -0.29 5.8e-01 AFF1 ATP6V0D1 C6orf106 NRBF2 PNMT SIDT2
LDL Cholesterol 1.33 4 3 9.1 -0.23 7.7e-01 C6orf106 CACFD1 ERGIC3 HECTD4
Neuroticism 1.07 2 1 3.0 0.00 1.0e+00 LRRC37A TCF4
Primary Biliary Cirrhosis 1.25 4 1 3.0 0.81 9.9e-02 CCDC153 HECTD4 LRRC37A PNMT
Rheumatoid Arthritis 1.12 1 0 0.0 0.00 1.0e+00 CCDC153
Schizophrenia 1.25 10 2 6.1 -0.07 8.4e-01 ABCB9 CA14 CUL3 MAD1L1 MRPS21 RP11-458I7.1 RP11-90P5.2 RPRD2 SBNO1 SETD8
Triglycerides 1.28 3 3 9.1 0.00 1.0e+00 AFF1 NRBF2 SIDT2
Ulcerative Colitis 1.37 6 4 12.1 -0.77 4.2e-02 ARFRP1 LIME1 PARK7 SDCCAG3 SLC22A5 STMN3
Blood Eosinophil Count 2.46 54 38 115.2 0.35 4.2e-03 ABCB9 AC034220.3 AC104532.4 AC113189.5 AHI1 ARL17B ATP6V0D1 CA14 CACFD1 CALM3 CARF CERS2 CHRNB1 CORO7 CRLF3 CTC-228N24.3 CTSS DLG4 EBPL EIF1AD GS1-393G12.12 HECTD4 HINT1 HLX HTR4 IQCH KM-PA-2 LRRC37A MAP2K5 MCM4 MCM6 MPHOSPH9 MRPS21 NOB1 NSF OGFOD2 P4HA2 PACS1 RIN3 RNF185 RP11-316M1.12 RP1-244F24.1 SDCCAG3 SEMA3B-AS1 SETD8 SKAP2 SLC22A5 SLC2A4RG SLC38A6 SMPD2 SUOX TOM1L2 TSEN2 ZBTB40
Blood Platelet Count 1.42 95 74 224.2 0.12 2.4e-01 ABCB9 AC034220.3 ADH1B ANKFY1 ARFRP1 BIN3 BOP1 C18orf8 C6orf106 CACFD1 CARF CCDC153 CDK5RAP3 CEP120 CERS2 CFL1 CHRNB1 CORO7 CRLF3 CTA-85E5.10 CTD-2323K18.1 CTD-3184A7.4 CTSS DCAF16 DIMT1 DIP2B DISP2 EIF3C FAM136A GMEB2 GSS HECTD4 HINT1 HLX HM13 HOXB-AS1 HSF1 KIAA1875 LIME1 LRRC37A LRRN2 MPHOSPH9 MRPS21 MSH6 MUC1 NFKBIL2 NRBF2 OGFOD2 OMG OSM P4HA2 PARK7 PDE12 PGAM5 PIAS1 PIEZO1 PLAGL2 PLXNA1 PNMT PROSER2 RAB7L1 RALY RIN3 RNASEH2C RP11-1084E5.1 RP11-316M1.12 RP11-378A13.1 RP11-458I7.1 RP11-6N17.10 RP11-6N17.9 RPRD2 SAMD4A SBNO1 SCMH1 SEMA3B-AS1 SETD8 SIDT2 SLC22A5 SLC25A5P1 SMG6 SMPD2 ST7L STAT4 STMN3 TBPL1 TCP11 TIGD2 TMEM194B TSEN2 VKORC1L1 WFIKKN1 ZGPAT ZNF577 ZNF641 ZNF654
Blood Red Count 1.52 66 51 154.5 -0.15 2.1e-01 ABCB8 AC113189.5 ACADS AFF1 AOC1 ARFRP1 ARL17B ASPSCR1 C6orf106 CACFD1 CALM3 CCNT2 CENPW CHP CLCNKA CNIH4 CNTROB DARS DCXR DOT1L EIF2AK4 EIF3C FAM136A GMEB2 GSS HECTD4 HM13 HOXB-AS1 HSF1 KIAA0174 LLGL2 LRRC37A LTBP4 MCM6 MST1P2 MUC1 MYADML2 NFAT5 NFKBIL2 NOB1 NRBF2 NSF PELI3 PIAS1 PNMT RIN1 RNASEH2C RP11-332H18.4 RP11-541N10.3 SBNO1 SEMA3B-AS1 SETD8 SNAI3-AS1 SPRYD4 STMN3 STX1B SUPT3H TBX10 TOM1L2 TSEN2 WFIKKN1 ZBTB38 ZBTB4 ZGPAT ZNF641 ZNF654
Blood White Count 1.43 69 44 133.3 -0.16 1.8e-01 AC016747.3 AC034220.3 AHI1 AP4E1 ARFRP1 BTBD7 C18orf8 CA14 CACFD1 CCDC126 CCDC153 CENPW CEP120 CHD7 CHP CLUAP1 CNIH4 CORO7 CTA-85E5.10 CTB-36H16.2 CTC-228N24.3 CTD-2323K18.1 CTD-3184A7.4 DCAF16 DIP2B EBPL EIF1AD EIF3C GFPT1 GGT7 GRK4 HECTD4 HINT1 HTR4 KRI1 LRRC37A MAP1LC3A MRPS21 MRPS36 NCOA6 NOB1 NRBF2 NUFIP2 P4HA2 PNMT PTCH1 RALY RIN3 RMI1 RNF123 RNF185 RP11-378A13.1 SCMH1 SDCCAG3 SLC22A5 SMPD2 ST3GAL6-AS1 STMN3 STX1B TCP11 TIGD2 TNFAIP8 TOM1L2 TULP4 UBXN2A VKORC1L1 ZGPAT ZNF577 ZSWIM7
Heel T-Score 1.98 102 70 212.1 0.14 1.2e-01 ABCB9 AFF1 ANAPC10 ANKFY1 AP4E1 ARL17B ASPSCR1 BMP4 BOP1 C18orf8 C1orf133 CACFD1 CCDC153 CCDC91 CDK2AP1 CEP120 CERS2 CHRNB1 CLCNKA CMSS1 CNIH4 COL21A1 COPS7B CORO7 CTA-85E5.10 CTB-36H16.2 CTC-228N24.3 CTSS DCAF16 DCXR DIP2B DLG1 DOT1L EBPL EEF1G EML3 EPB41L2 EYA2 FIP1L1 FLI1 GGT7 GLDN GS1-393G12.12 GSS HLX HSPA4 IPO8 IQCH JAG1 KIAA0174 KM-PA-2 LIME1 LIN28B LRRC37A MAP1LC3A MAP2K5 MCM4 MPHOSPH9 MRAS MRPL21 MRPS21 MRPS35 MSH6 MTA2 MUC1 NCOA6 NSF OGFOD2 OSM PDE12 PLCD3 RALY RIOK1 RNASEH2C ROM1 RP11-250B2.6 RP11-378A13.1 RP11-860B13.1 RP11-967K21.1 RPRD2 RPS20 RRP15 SBNO1 SCMH1 SEC24C SETD8 SKAP2 SLC2A4RG SLC9A3R2 SNAI3-AS1 ST7L STRA13 STX1B TONSL TRAF3IP1 TSPAN9 TWIST1 ZBTB38 ZBTB4 ZBTB40 ZNF200 ZNF641
BMI 1.64 69 38 115.2 -0.54 1.1e-06 AC113189.5 ANKFY1 ARFGEF2 ARHGAP12 BTBD7 C18orf8 C6orf106 CARF CCDC171 CDK5RAP3 CEP120 CHRNB1 CLUAP1 CRIM1 CTD-2201E18.3 CTD-3184A7.4 CWC27 DCAF16 DLG1 DLG4 EIF2AK4 EIF3C EML2 FOXO3 GGT7 HINT1 HLX HTR4 IQCH KIAA1598 MAP1LC3A MAP2K5 MLLT10 MRPL21 MST1P2 NCOA6 NFAT5 NOB1 NOP58 NR2F1 NR3C1 NRBF2 PCYT1A PNMAL1 PYGB RALY RNF123 RP11-449D8.5 RP11-538P18.2 RP11-613D13.5 RP11-6N17.10 RP11-6N17.9 RP1-283E3.4 SEMA3B-AS1 SF3B3 SLC25A5P1 SLC9A3R2 SPRYD4 STMN3 STRA13 STX1B SUOX TCP11 UBN1 VAC14-AS1 ZCCHC24 ZMAT2 ZNF654 ZSWIM7
Height 3.95 186 167 506.1 -0.26 1.5e-04 ABCB9 AC034220.3 AC062029.1 ACTG1 AHI1 ALDH6A1 ANAPC10 AOC1 AP4E1 ARFGEF2 ARFRP1 ARL17B ASPSCR1 ATP6V0D1 B3GNT7 BMF BOK BOP1 BRAF C10orf11 C18orf8 C2orf54 C6orf106 CA14 CACFD1 CARF CCDC126 CCDC91 CD79B CDK2AP1 CDK5RAP3 CENPW CEP120 CEP250 CEP63 CHD7 CHP CHRNB1 CMSS1 CNIH4 CNTROB COG4 COPS7B CPE CPZ CRIM1 CRLF3 CTA-85E5.10 CTC-228N24.3 CTD-2323K18.1 CTD-3232M19.2 CYTL1 DCAF16 DCC DCXR DIP2B DISP2 DNA2 DOT1L DPP3 DYNLL1-AS1 EBPL EFEMP1 EIF1AD EIF2AK4 EIF4E2 ERC1 ERGIC3 FAM136A FBXW8 FLI1 FOXO3 GGT7 GLB1 GSS HECTD4 HINT1 HLX HM13 IPO8 IQCH JAG1 KIAA1875 KM-PA-2 LIME1 LIN28B LLGL2 LRRC37A LTBP1 LTBP4 MAP1LC3A MCM4 MDM4 MPHOSPH9 MRAS MRPS33 MRPS35 MRPS6 MSH6 MST1P2 MUC1 MYADML2 MYO6 NCOA6 NDST1 NDUFB2-AS1 NFAT5 NOB1 NOL8 NOP58 NPC2 NQO1 NR3C1 NSF NUDT6 NUFIP2 OGFOD2 OMG P4HA2 PARK7 PBLD PDIK1L PELI3 PIEZO1 PLCD3 PRDM11 PROSER2 PTCH1 PYGB QSOX2 RAB7L1 RAD18 RALY RBBP8 RMI1 RP11-171I2.2 RP11-332H18.4 RP11-378A13.1 RP11-477D19.2 RP11-529H20.5 RP11-538P18.2 RP11-6N17.10 RP11-860B13.1 RP11-90P5.2 RP11-967K21.1 RPS20 RRP15 SAMD4A SBNO1 SCMH1 SDCCAG3 SEMA3B-AS1 SENP6 SEPT9 SETD8 SF3B2 SLC22A5 SLC2A4RG SLC2A9 SLC9A3R2 SMG6 SMPD2 SMURF2 SNAI3-AS1 SNX13 ST7L STMN3 STRA13 SUSD5 TBC1D30 TCF4 TCP11 TEFM TMTC4 TOM1L2 TONSL TRAF3IP1 TSEN2 TULP4 UBXN2A UQCC VKORC1L1 WFIKKN1 ZBTB38 ZBTB4 ZNF641
Waist Hip Ratio (WHR) 2.22 64 46 139.4 -0.22 6.5e-02 ABCB9 AC004540.4 AC113189.5 ANAPC10 ANKFY1 ASPSCR1 C6orf106 CENPW CEP250 CHRNB1 CMSS1 CNTROB CORO7 CTC-228N24.3 CTD-2323K18.1 CYTL1 DISP2 DOT1L EBPL EEF1G EML2 EML3 EYA2 GANAB GGT7 HLX HSPA4 LRRC37A MAP2K5 MPHOSPH9 MRAS MRPS35 MRPS7 MST1P2 MTA2 MUC1 MYADML2 NCOA6 NFAT5 NOL8 NRBF2 NSF OGFOD2 OPRL1 OSM PLCE1 RNASEH2C ROM1 RP11-23P13.7 RP11-250B2.6 RP11-332H18.4 RP11-529H20.5 SBNO1 SEMA3B-AS1 SETD8 TFG TNFAIP8 TOM1L2 TSEN2 UQCC ZBTB4 ZCCHC24 ZNF200 ZSWIM7
Systolic Blood Pressure 1.52 61 31 93.9 -0.09 4.8e-01 ADAMTS8 ARFGEF2 BMP4 CALML6 CAMK1D CARF CCNT2 CDC123 CEP63 CFL1 CHP CLCNKA CMSS1 COG4 COL21A1 CORO7 CTC-228N24.3 DCAF16 DCLK2 DLG4 EFEMP1 EPB41L2 ERGIC3 FOXO3 GMEB2 HECTD4 HSPA4 HTR4 IL34 LRRC37A MICAL3 MRAS NSF OPRL1 PCYT1A RIN3 RN7SL793P RNASEH2C RNF123 RP11-332H18.4 RP11-378A13.1 RP11-538P18.2 RP11-541N10.3 RP11-90P5.2 SEPT9 SF3B3 SIDT2 SLC12A2 SLC9A3R2 SMG6 TMBIM1 TMEM194B TNFAIP8 UBN1 UBXN2A UQCC VAC14-AS1 ZGPAT ZMAT2 ZNF641 ZNF654
Smoking Status 1.63 16 4 12.1 0.25 3.5e-01 COG4 IQCH MAP2K5 MLLT10 MRPS6 MSH6 NOB1 NUFIP2 PLAGL2 RNF123 SLC25A5P1 STMN3 SUOX USP14 WFIKKN1 ZFHX3
Allergy or Eczema 1.55 19 15 45.5 -0.52 1.8e-02 ABCB9 AHI1 ARFRP1 C6orf106 CHP CTD-3184A7.4 EIF1AD GMEB2 HECTD4 LIME1 MPHOSPH9 MRPS33 OGFOD2 RP11-574K11.5 SETD8 STMN3 SUOX ZBTB38 ZGPAT
Cardiovascular Disease 1.55 34 12 36.4 -0.29 8.0e-02 ANKFY1 C18orf8 C1GALT1 CHP CLCNKA CRLF3 CTC-228N24.3 DCAF16 DLG4 GMEB2 HECTD4 HSF1 HTR4 IL34 MAP2K5 MRAS NOP58 OPRL1 PIAS1 RP11-332H18.4 RP11-378A13.1 RP11-538P18.2 RP11-613D13.5 SF3B3 SIDT2 SLC12A2 SLC22A5 STX1B TCP11 TMBIM1 VAC14-AS1 XRN2 ZGPAT ZNF641
Hypothyroidism (self reported) 1.25 5 3 9.1 -0.29 6.3e-01 AHI1 CTA-85E5.10 HECTD4 SUOX TMEM194B
Respiratory disease 1.80 16 11 33.3 -0.21 3.8e-01 AC034220.3 AHI1 ARFRP1 CARF CCDC153 IQCH LIME1 MAP2K5 P4HA2 PNMT RNF123 RP11-574K11.5 SLC22A5 STMN3 SUOX ZGPAT
Type 2 Diabetes (T2D) 1.78 13 7 21.2 -0.68 1.0e-02 ANKFY1 C1GALT1 CAMK1D CENPW CTD-2323K18.1 EML2 HSF1 MRAS NFKBIL2 NOB1 RNF123 STARD10 ZCCHC24
Lung FEV1/FVC ratio 2.84 77 57 172.7 -0.19 8.6e-02 ABLIM3 ACTG1 ANKFY1 ARHGAP12 ATP6V0D1 BIN3 BMF BMP4 BTBD1 C10orf11 C1GALT1 C6orf106 CAMK1D CARF CCDC171 CDC123 CENPW CFHR3 CHRNB1 CLCNKA CTA-85E5.10 CTC-228N24.3 DSP EFEMP1 EIF2AK4 ERC1 FOXO3 GPD2 GSS HLX HOXB-AS1 HTR4 INTS12 ITGA2 LLGL2 LONRF2 LRRC37A LTBP4 MAP1LC3A MICAL3 MLLT10 MRPS35 MRPS6 MST1P2 NCOA6 NRBF2 NSF P4HA2 PAIP1 PAK6 PDE12 PIBF1 PSMA4 PTCH1 RAB7L1 RALY ROM1 RP11-23P13.7 RP11-574K11.5 RPS20 RRP15 SEC24C SLC22A5 SLC2A9 SLC38A6 SMURF2 SOGA2 STARD10 STRA13 SUOX TBX3 TCP11 TEFM TIGD2 TRAF3IP1 ZBTB38 ZFHX3
Neuroticism 1.44 10 7 21.2 -0.74 5.7e-03 ACTG1 ARL17B CENPW IQCH LRRC37A MAP2K5 NSF PTCH1 TCF4 UBXN2A
Chronotype (morning person) 1.27 5 4 12.1 -0.52 3.6e-01 RP11-316M1.12 SDCCAG3 SEMA3B-AS1 SLC25A5P1 TRAF3IP1
Hair Pigment 0.92 51 39 118.2 0.49 1.1e-04 ABCB9 ACTG1 ASPSCR1 B3GNT1 BRAF BTBD1 CCDC57 CDK5RAP3 CEP250 CTC-228N24.3 DCXR DHDDS DNAJB12 DPP3 ERGIC3 FAM136A FOXO3 GGT7 HECTD4 HM13 LRRC37A LRRN2 MAP1LC3A MPHOSPH9 MRAS MRPL21 MYADML2 NCOA6 NNT OGFOD2 OPRL1 PELI3 PIEZO1 PLXNA1 RAB7L1 RALY RNASEH2C RP11-6N17.10 RP11-6N17.9 SETD8 SNAI3-AS1 STAT4 STMN3 STRA13 SUOX TBC1D30 TBX10 TWIST1 UQCC ZBTB38 ZCCHC24
Tanning 1.23 17 14 42.4 -0.51 3.7e-02 ACTG1 CEP250 CERS2 CORO7 CTSS ERGIC3 GGT7 HECTD4 MAP1LC3A NCOA6 NOX4 PIEZO1 PLAGL2 RALY RP11-316M1.12 SNAI3-AS1 UQCC
Hand grip strength (left) 2.28 31 19 57.6 -0.09 6.3e-01 AC034220.3 AOC1 ARFGEF2 BRAF CCNT2 CD79B CEP250 DARS DCAF16 DOT1L ERGIC3 GSS HINT1 HOXB-AS1 JAG1 LIN28B LRRC37A MAP1LC3A NCOA6 NOB1 NSF P4HA2 RAB7L1 RP11-171I2.2 RP11-191L17.1 SLC9A3R2 STX1B TCF4 UQCC WDR18 ZBTB38
Number of treatments/medications taken 1.31 3 1 3.0 0.00 1.0e+00 HECTD4 MLLT10 RNF123
Sensitivity / hurt feelings 1.29 4 4 12.1 0.69 1.9e-01 ARL17B LRRC37A NSF PTCH1
Hearing difficulty/problems: Yes 1.22 1 1 3.0 0.00 1.0e+00 ABLIM3
Relative age of first facial hair 1.65 12 5 15.2 0.50 8.4e-02 C6orf106 EIF4E2 FOXO3 GGT7 IL34 LIN28B LRRC37A NCOA6 NSF SEMA3B-AS1 TWIST1 ZBTB38
Ever used hormone-replacement therapy (HRT) 1.13 1 0 0.0 0.00 1.0e+00 BCDIN3D
Systolic blood pressure, automated reading 1.50 23 15 45.5 0.25 2.3e-01 ADAMTS8 CAMK1D CCNT2 CHP COL21A1 CTC-228N24.3 DCAF16 DLG4 GMEB2 HECTD4 HTR4 LRRC37A NSF OPRL1 PRDM11 RP11-332H18.4 RP11-538P18.2 RP11-541N10.3 SLC12A2 SMG6 STMN3 UBXN2A ZGPAT
Medication for hormone replacement therapy 1.13 1 0 0.0 0.00 1.0e+00 RP1-199J3.5
Medication: Metformin 1.55 3 1 3.0 0.00 1.0e+00 CAMK1D MRAS ZCCHC24
Diabetes (mother) 1.41 2 2 6.1 0.00 1.0e+00 CAMK1D STARD10
Pack years adult smoking proportion 1.75 1 1 3.0 0.00 1.0e+00 PSMA4
Impedance of leg (right) 2.28 59 35 106.1 0.27 3.0e-02 AOC1 B3GNT1 C6orf106 CD79B CEP120 CEP250 CLUAP1 CTA-85E5.10 CTC-228N24.3 CTD-3232M19.2 CTSS CYTL1 DHDDS DIP2B DNA2 EIF3C EML2 ERGIC3 GGT7 GLB1 GS1-393G12.12 HINT1 HLX KM-PA-2 LIN28B LRRC37A LTBP1 MAP1LC3A MRPL21 MST1P2 MUC1 NCOA6 NOL8 NUDT6 OLFM2 PIAS1 PLCE1 PTCH1 RAB7L1 RALY RIN1 RIN3 RNF123 RP11-23P13.7 RP11-458I7.1 RP11-90P5.2 RPS20 SEMA3B-AS1 SLC12A2 SLC2A4RG SLC9A3R2 SMG6 SNAI3-AS1 STX1B SUOX SUPT3H TOM1L2 UQCC ZNF641
Leg fat-free mass (left) 2.82 75 57 172.7 0.26 1.8e-02 ABCB9 AC034220.3 ACTG1 ANAPC10 AOC1 BOK C18orf8 C6orf106 CALML6 CCDC91 CD79B CDK5RAP3 CENPW CEP120 CEP250 CHRNB1 CLUAP1 CNIH4 COPS7B CRIM1 CRLF3 CTC-228N24.3 DCAF16 DHDDS DNA2 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C ERGIC3 FOXO3 GGT7 GLB1 GSS HECTD4 HINT1 IPO8 IQCH KIAA1598 MAP1LC3A MAP2K5 MPHOSPH9 MRPL21 MUC1 NCOA6 NR3C1 NUDT6 OGFOD2 OMG P4HA2 PBLD PDIK1L PNMAL1 PTCH1 RAB7L1 RALY RIN3 RNF123 RP11-332H18.4 RP11-613D13.5 RP11-967K21.1 RPS20 SCMH1 SETD8 SLC12A2 SLC9A3R2 SMPD2 STX1B SUOX SUPT3H TEFM UQCC ZBTB38 ZNF654
Trunk fat percentage 1.98 46 30 90.9 0.55 3.2e-05 ARFRP1 C18orf8 C6orf106 CCDC171 CDK5RAP3 CENPW CRIM1 CTSS CWC27 DARS DIP2B DLG1 DNA2 EFEMP1 EIF3C EML3 FOXO3 GANAB GFPT1 HTR4 IQCH KIAA1598 LIME1 LRRC37A MAP2K5 MCM6 MLLT10 MRPS21 NOB1 NSF OLFM2 PACS1 PYGB RIN3 RMI1 ROM1 RP11-613D13.5 RP11-6N17.10 RP11-6N17.9 RP1-283E3.4 SLC2A4RG SLC9A3R2 ST7L STX1B TCP11 ZBTB38
Hand grip strength (right) 2.28 32 19 57.6 -0.06 7.2e-01 AC034220.3 AOC1 ARFGEF2 C6orf106 CCNT2 CD79B CEP250 CTD-2323K18.1 DARS DCAF16 DOT1L EIF3C ERGIC3 GSS HINT1 HOXB-AS1 JAG1 LIN28B LRRC37A MAP1LC3A NCOA6 NOB1 NSF P4HA2 PLCD3 RAB7L1 RP11-171I2.2 RP11-191L17.1 RP11-317J10.2 SCMH1 UQCC ZBTB38
Townsend deprivation index at recruitment 1.05 1 0 0.0 0.00 1.0e+00 MAP2K5
Current tobacco smoking 1.48 5 1 3.0 0.41 4.2e-01 ARFRP1 CARF CUL3 NUFIP2 STMN3
Fed-up feelings 1.43 5 3 9.1 0.75 8.7e-02 B3GNT1 DCC HECTD4 LRRC37A NSF
Frequency of unenthusiasm / disinterest in last 2 weeks 1.50 2 0 0.0 0.00 1.0e+00 DCC NRBF2
Relative age voice broke 1.43 6 3 9.1 0.28 5.5e-01 FOXO3 LIN28B LRRC37A NSF SCMH1 UQCC
Taking other prescription medications 1.31 3 1 3.0 0.00 1.0e+00 AHI1 HECTD4 RNF123
Age when periods started (menarche) 1.90 16 9 27.3 0.26 2.9e-01 AC016747.3 CENPW CHP FOXO3 GGT7 IQCH LIN28B MAP2K5 MSH6 NFAT5 NOB1 OLFM2 RNASEH2C RP11-422P24.10 SEMA3B-AS1 ZNF654
Heel bone mineral density (BMD) T-score, automated (left) 1.45 7 2 6.1 0.02 9.7e-01 BMP4 EBPL EYA2 GGT7 NCOA6 RNASEH2C ST7L
High blood pressure 1.49 16 9 27.3 0.04 8.8e-01 AC034220.3 C1GALT1 CHP DCAF16 DLG4 GMEB2 HECTD4 HTR4 IQCH MAP2K5 MRAS OPRL1 RP11-332H18.4 RP11-538P18.2 STX1B VAC14-AS1
Hayfever, allergic rhinitis or eczema 1.55 17 9 27.3 0.33 1.8e-01 ABCB9 AHI1 ARFRP1 CHP CTD-3184A7.4 EIF1AD LIME1 MPHOSPH9 MRPS33 OGFOD2 P4HA2 SETD8 SLC22A5 STMN3 SUOX ZBTB38 ZGPAT
Multivitamins +/- minerals 1.19 1 0 0.0 0.00 1.0e+00 MAP1LC3A
Medication: Atenolol 1.16 1 1 3.0 0.00 1.0e+00 HECTD4
Medication: Levothyroxine sodium 1.19 2 2 6.1 0.00 1.0e+00 HECTD4 SUOX
Sitting height 3.92 112 94 284.8 0.12 1.6e-01 ABCB9 AC034220.3 AC062029.1 AC079742.4 ANAPC10 AOC1 ARFGEF2 ARID3B ARL17B ASPSCR1 BOK BOP1 C18orf8 C6orf106 CA14 CACFD1 CCDC126 CCDC171 CCDC91 CD79B CDK2AP1 CENPW CEP120 CEP250 CHP CHRNB1 CNIH4 CNTROB COG4 COPS7B CORO7 CPE CPZ CRIM1 CRLF3 CTD-2323K18.1 CTD-3232M19.2 DCAF16 DCC DCXR DNA2 DOT1L EBPL EFEMP1 EIF2AK4 EIF4E2 ERC1 ERGIC3 EYA2 FAM136A FBXW8 FOXO3 GGT7 GLB1 GSS HINT1 HM13 JAG1 KIAA1875 KM-PA-2 LRRC37A LTBP1 MAP1LC3A MPHOSPH9 MST1P2 MYADML2 NCOA6 NFAT5 NOB1 NQO1 NSF NUDT6 OGFOD2 P4HA2 PARK7 PBLD PDIK1L PLAGL2 PLCD3 PROSER2 PTCH1 PYGB QSOX2 RAB7L1 RALY RP11-171I2.2 RP11-250B2.6 RP11-529H20.5 RP11-538P18.2 RP11-967K21.1 RPS20 SAMD4A SBNO1 SCMH1 SDCCAG3 SENP6 SETD8 SLC9A3R2 SMPD2 SNAI3-AS1 SNX13 ST3GAL6-AS1 SUPT3H TBC1D30 TULP4 UBXN2A UQCC WFIKKN1 ZBTB38 ZBTB4 ZNF438 ZNF641
Chronic bronchitis/emphysema (father) 1.45 1 1 3.0 0.00 1.0e+00 PSMA4
Body mass index (BMI) 1.50 33 20 60.6 0.70 4.2e-06 ARFGEF2 BTBD7 C18orf8 C6orf106 CALML6 CCDC171 CCNT2 CDK5RAP3 CEP120 CLUAP1 CTD-3184A7.4 CWC27 DCAF16 EIF3C FOXO3 GGT7 HTR4 IQCH KIAA1598 MAP2K5 MCM6 MLLT10 NOB1 NR2F1 NRBF2 RNF123 RP11-613D13.5 RP1-283E3.4 SLC9A3R2 STX1B SUOX TCP11 ZNF654
Impedance of leg (left) 2.37 55 35 106.1 0.19 1.5e-01 AOC1 CD79B CEP120 CEP250 CLUAP1 CTC-228N24.3 CTSS CYTL1 DHDDS DIP2B DNA2 EIF3C EML2 ERGIC3 GGT7 GLB1 GS1-393G12.12 HINT1 HLX HOXB-AS1 KM-PA-2 LIN28B LRRC37A LTBP1 MAP1LC3A MRPL21 MST1P2 MUC1 NCOA6 NOL8 NSF NUDT6 OLFM2 PIAS1 RAB7L1 RALY RIN1 RIN3 RNF123 RNF185 RP11-458I7.1 RP11-90P5.2 RPS20 SEMA3B-AS1 SLC12A2 SLC2A4RG SLC9A3R2 SMG6 SMPD2 STX1B SUOX SUPT3H TOM1L2 UQCC ZNF641
Leg predicted mass (left) 2.82 75 57 172.7 0.25 1.9e-02 ABCB9 AC034220.3 ACTG1 ANAPC10 AOC1 BOK C18orf8 C6orf106 CALML6 CCDC91 CD79B CDK5RAP3 CENPW CEP120 CEP250 CHRNB1 CNIH4 COPS7B CRIM1 CRLF3 CTC-228N24.3 DCAF16 DHDDS DNA2 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C ERGIC3 FOXO3 GGT7 GLB1 GSS HECTD4 HINT1 IPO8 IQCH KIAA1598 MAP1LC3A MAP2K5 MPHOSPH9 MRPL21 MUC1 NCOA6 NR3C1 NUDT6 OGFOD2 OMG P4HA2 PBLD PDIK1L PNMAL1 PTCH1 RAB7L1 RALY RIN3 RNF123 RP11-332H18.4 RP11-613D13.5 RP11-90P5.2 RP11-967K21.1 RPS20 SCMH1 SETD8 SLC12A2 SLC9A3R2 SMPD2 STX1B SUOX SUPT3H TEFM UQCC ZBTB38 ZNF654
Trunk fat mass 2.05 52 37 112.1 0.55 1.0e-05 ANAPC10 ARFRP1 C18orf8 C6orf106 CCDC171 CDK5RAP3 CEP120 CEP250 CRIM1 CTD-2201E18.3 CWC27 DLG1 DLG4 DYNLL1-AS1 EFEMP1 EIF2AK4 EIF3C ERGIC3 FOXO3 GGT7 HINT1 HTR4 IQCH KIAA1598 LIME1 LIN28B LRRC37A MAP1LC3A MAP2K5 MCM6 MLLT10 MRPS21 NCOA6 NOB1 NR3C1 NSF PCYT1A PYGB RNF123 RP11-613D13.5 RP11-6N17.10 RP11-6N17.9 RP11-967K21.1 RP1-283E3.4 SLC2A4RG SLC9A3R2 ST7L STX1B TCP11 UQCC ZBTB38 ZNF654
Waist circumference 1.75 36 25 75.8 0.66 5.8e-06 AC004540.4 ARFRP1 BTBD7 C18orf8 C6orf106 CALML6 CCDC171 CDK5RAP3 CEP120 CRIM1 CWC27 DLG4 EIF3C FOXO3 GGT7 HINT1 HTR4 IQCH KIAA1598 LIME1 MAP2K5 MLLT10 NOB1 NR3C1 PYGB RNASEH2C RNF123 RP11-613D13.5 RP11-6N17.9 RP1-283E3.4 SLC9A3R2 STX1B TCP11 ZBTB38 ZCCHC24 ZNF654
Number of incorrect matches in round 1.19 2 0 0.0 0.00 1.0e+00 RIN1 STX1B
Past tobacco smoking 1.48 7 2 6.1 0.58 1.3e-01 GGT7 IQCH MAP1LC3A MAP2K5 MLLT10 MSH6 NOB1
Alcohol usually taken with meals 1.48 1 0 0.0 0.00 1.0e+00 CHRNB1
Nervous feelings 1.28 4 2 6.1 0.98 2.2e-03 CENPW IQCH LRRC37A NSF
Frequency of tenseness / restlessness in last 2 weeks 1.30 4 2 6.1 0.97 4.9e-03 ARL17B LRRC37A NSF RNF123
Hearing difficulty/problems with background noise 1.36 3 1 3.0 0.00 1.0e+00 LIN28B LRRC37A RAB7L1
Hair/balding pattern: Pattern 2 1.37 4 3 9.1 0.76 1.3e-01 C10orf11 LRRC37A NSF TWIST1
Had menopause 1.12 1 0 0.0 0.00 1.0e+00 CHP
Forced vital capacity (FVC) 4.89 155 93 281.8 -0.91 1.6e-65 ABLIM3 AC073834.3 AC079742.4 AC104532.4 AHI1 AIMP2 ANAPC10 ANGPTL1 AOC1 AP4E1 ARFGEF2 ARFRP1 ARID3B ARL17B ASPSCR1 BCDIN3D BMF BOK BRAF BTBD1 C10orf11 C2orf54 C6orf106 CACFD1 CAMK1D CARF CCDC126 CCDC171 CCDC57 CCDC88A CCNT2 CD79B CDC123 CENPW CEP120 CFHR3 CFL1 CLCNKA CLUAP1 COG4 CPE CRIM1 CTA-85E5.10 CTB-36H16.2 CTC-228N24.3 CTD-2323K18.1 CTD-3184A7.4 CTSS CUL3 DARS DCAF16 DCXR DHDDS DLG1 DPP3 EBPL EFEMP1 EIF2AK4 EIF4E3 EML2 EML3 EPB41L2 ERC1 EYA2 FAM136A GANAB GMEB2 GOLGA6L9 GRK4 HTR4 IGFBP7 INTS12 IPO8 IQCH JAG1 LIME1 LONRF2 LRPAP1 LRRC37A LRRIQ1 LTBP4 MAP2 MAP2K5 MCM6 MDM4 METTL22 MLLT10 MRPL21 MRPS33 MRPS35 MST1P2 MUC1 MYADML2 NDUFB2-AS1 NFAT5 NOB1 NOP58 NOX4 NQO1 NSF OSM PDE12 PDIK1L PELI3 PGAM5 PLCD3 PNMT PRDM11 PSMA4 PTCH1 PYGB QSOX2 RAB3IL1 RIN3 RNF123 RP11-250B2.6 RP11-316M1.12 RP11-378A13.1 RP11-449D8.5 RP11-538P18.2 RP11-541N10.3 RP11-574K11.5 RP11-967K21.1 RPS20 RRP15 SCMH1 SEC14L1 SEC24C SEP15 SF3B2 SF3B3 SHROOM3 SLC12A2 SLC2A4RG SMG7 SMPD2 SMURF2 SNAI3-AS1 STMN3 STX1B SUSD5 TBC1D30 TCP11 TULP4 UBXN2A UQCC USP14 WBP1L WDR18 ZBTB38 ZCCHC24 ZFP82 ZGPAT ZMAT2 ZNF438
Heel bone mineral density (BMD) T-score, automated (right) 1.49 4 2 6.1 -0.65 3.5e-01 BMP4 EYA2 NCOA6 ST7L
Ever unenthusiastic/disinterested for a whole week 1.12 3 1 3.0 0.94 5.8e-02 LRRC37A NSF ZMAT2
Qualifications: None of the above 1.44 12 9 27.3 -0.32 2.9e-01 ABCB9 B3GNT1 BCDIN3D EIF3C FOXO3 MPHOSPH9 NRBF2 OGFOD2 RNF123 SBNO1 SETD8 SUOX
Mouth/teeth dental problems 1.27 1 0 0.0 0.00 1.0e+00 MCM6
Heart attack 1.25 1 0 0.0 0.00 1.0e+00 TOM1L2
Allergy 1.78 23 16 48.5 -0.08 6.9e-01 ABCB9 AC034220.3 AHI1 ARFRP1 CCDC153 CHP CTD-3184A7.4 HINT1 LIME1 MAP2K5 MPHOSPH9 MRPS33 OGFOD2 P4HA2 RBBP8 RP11-574K11.5 SBNO1 SETD8 SLC22A5 STMN3 SUOX ZBTB38 ZGPAT
Diabetes (self-reported) 1.71 4 1 3.0 0.99 1.2e-03 C1GALT1 CAMK1D CTC-228N24.3 ZCCHC24
Medication: Simvastatin 1.37 2 0 0.0 0.00 1.0e+00 CTC-228N24.3 OPRL1
Fluid intelligence score 1.35 11 4 12.1 0.22 5.0e-01 ABCB9 DCAF16 EIF3C FOXO3 HSF1 KIFC2 MPHOSPH9 NFKBIL2 RNF123 SETD8 SUOX
Illnesses of siblings 1.23 2 0 0.0 0.00 1.0e+00 HECTD4 STX1B
Neuroticism score 1.35 9 5 15.2 0.75 1.2e-02 ARL17B LRRC37A NSF PTCH1 RNF123 SEMA3B-AS1 TCF4 UBN1 UBXN2A
Weight 2.31 69 49 148.5 0.47 2.1e-05 AC034220.3 ANAPC10 ARFRP1 BOK BTBD7 C18orf8 C6orf106 CALML6 CCDC171 CD79B CDK5RAP3 CENPW CEP120 CEP250 COPS7B CRIM1 CRLF3 CWC27 DCAF16 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C EIF4E2 ERGIC3 FOXO3 GGT7 GSS HECTD4 HINT1 HTR4 IQCH KIAA1598 LIME1 MAP1LC3A MAP2K5 MCM6 MLLT10 MRPL21 MUC1 NCOA6 NR2F1 NR3C1 OMG P4HA2 PCYT1A PYGB RAB7L1 RALY RNF123 RP11-332H18.4 RP11-613D13.5 RP11-967K21.1 RP1-283E3.4 RPS20 SCMH1 SENP6 SETD8 SLC25A5P1 SLC9A3R2 SMPD2 STX1B SUOX TEFM UQCC ZBTB38 ZMAT2 ZNF654
Impedance of arm (right) 1.67 55 41 124.2 0.30 2.0e-02 AOC1 ARL17B BOP1 CALML6 CENPW CEP120 CTA-85E5.10 CTD-3232M19.2 CTSS DHDDS DIP2B EEF1G EFEMP1 EML3 ERGIC3 FOXO3 GANAB GGT7 GS1-393G12.12 HLX KM-PA-2 LIN28B LRPAP1 LRRC37A LTBP1 MAP1LC3A MLLT10 MST1P2 MTA2 MUC1 NCOA6 NOL8 NRBF2 NSF NUFIP2 OLFM2 PIAS1 PNMAL1 RALY RIN3 RMI1 RNF123 RNF185 ROM1 RP11-529H20.5 RPS20 SCMH1 SEMA3B-AS1 SLC2A4RG SLC9A3R2 ST7L STX1B SUOX TFG ZNF641
Arm fat percentage (right) 1.78 37 22 66.7 0.64 1.3e-05 ARFGEF2 ARFRP1 C18orf8 C6orf106 CARF CCDC171 CCNT2 CD79B CDK5RAP3 CENPW CRIM1 CWC27 DCAF16 DLG1 DLG4 DPP3 EIF3C GRK4 HTR4 IQCH KIAA1598 MAP2K5 MCM6 MLLT10 NOB1 NOP58 PYGB RNF123 RP11-449D8.5 RP11-613D13.5 RP11-6N17.9 RP11-967K21.1 RP1-283E3.4 SLC2A4RG STX1B TCP11 ZNF654
Trunk fat-free mass 3.22 90 71 215.2 0.31 1.1e-03 ABCB9 AC034220.3 AC062029.1 ANAPC10 AOC1 ARFGEF2 B3GNT7 BOK C18orf8 C6orf106 CALML6 CCDC91 CD79B CENPW CEP120 CEP250 CHP CHRNB1 CNIH4 CNTROB COPS7B CRIM1 CRLF3 CTC-228N24.3 CTD-2323K18.1 DCAF16 DHDDS DNA2 DOT1L EBPL EFEMP1 EIF2AK4 EIF4E2 ERGIC3 FBXW8 FOXO3 GGT7 GSS HECTD4 HINT1 IPO8 KIAA1598 LIN28B MAP1LC3A MPHOSPH9 MRPL21 MST1P2 MUC1 NCOA6 NR3C1 NUDT6 OGFOD2 OMG P4HA2 PARK7 PBLD PDIK1L PNMAL1 PTCH1 QSOX2 RAB7L1 RALY RBBP8 RIN3 RNF123 RP11-332H18.4 RP11-477D19.2 RP11-529H20.5 RP11-613D13.5 RP11-967K21.1 RPS20 SBNO1 SCMH1 SDCCAG3 SENP6 SETD8 SLC25A5P1 SLC9A3R2 SMPD2 SNAI3-AS1 SNX13 SUOX TBC1D30 TEFM UBXN2A UQCC ZBTB38 ZBTB4 ZMAT2 ZNF654
Hip circumference 2.03 53 40 121.2 0.53 2.3e-05 ANAPC10 ARFRP1 BOK BTBD7 C18orf8 C6orf106 CCDC171 CDK5RAP3 CEP120 CEP250 CRIM1 CRLF3 DCXR DLG4 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C ERGIC3 EYA2 FOXO3 GGT7 HECTD4 HINT1 HTR4 IQCH KIAA1598 LIME1 MAP1LC3A MAP2K5 MLLT10 MRPS21 NCOA6 NOB1 NR3C1 OMG PCYT1A RALY RNF123 RP11-613D13.5 RP11-967K21.1 RP1-283E3.4 SENP6 SLC9A3R2 STMN3 STX1B TCP11 TEFM UQCC ZBTB38 ZMAT2 ZNF654
Father's age at death 1.30 1 1 3.0 0.00 1.0e+00 PSMA4
Worrier / anxious feelings 1.18 5 3 9.1 0.34 5.1e-01 LRRC37A NSF PTCH1 STX1B TCF4
Hair/balding pattern: Pattern 3 1.61 6 5 15.2 -0.64 1.2e-01 ARL17B CENPW LRRC37A MAP1LC3A NSF TWIST1
Number of live births 1.32 3 0 0.0 0.00 1.0e+00 CTA-85E5.10 KIAA1598 LRRC37A
Forced expiratory volume in 1-second (FEV1) 4.54 114 74 224.2 -0.92 2.1e-51 ABLIM3 AC073834.3 AC104532.4 AHI1 ANAPC10 ANGPTL1 AOC1 ARFGEF2 ARFRP1 ARID3B ARL17B ASPSCR1 BOK BRAF BTBD1 C10orf11 C1GALT1 C6orf106 CACFD1 CAMK1D CCDC126 CCDC171 CCNT2 CD79B CDC123 CENPW CEP120 CLUAP1 COG4 CRIM1 CTA-85E5.10 CTB-36H16.2 CTD-2323K18.1 CTD-3184A7.4 CTSS DARS DCAF16 DCXR DHDDS DLG1 DPP3 EBPL EEF1G EFEMP1 EML3 GANAB GOLGA6L9 GPD2 HSPA4 HTR4 IGFBP7 INTS12 IPO8 JAG1 LLGL2 LONRF2 LRPAP1 LRRC37A LRRIQ1 MCM6 MDM4 MICAL3 MRPL21 MST1P2 MUC1 MYADML2 NFAT5 NOB1 NQO1 NSF OSM PDE12 PDIK1L PELI3 PGAM5 PLAGL2 PLCD3 PRDM11 PSMA4 PTCH1 PYGB QSOX2 RAB3IL1 RIN3 RNF123 RNF185 ROM1 RP11-378A13.1 RP11-538P18.2 RP11-541N10.3 RP11-574K11.5 RP11-967K21.1 SCMH1 SEC24C SF3B2 SF3B3 SH3RF1 SMG7 SMPD2 SMURF2 SNAI3-AS1 SOGA2 STX1B SUOX SUSD5 TBC1D30 TCP11 TULP4 UBXN2A VPS29 WBP1L ZBTB38 ZCCHC24 ZGPAT
Pulse rate 1.16 4 2 6.1 1.00 2.7e-03 B3GNT7 CEP120 TOM1L2 ZBTB38
Qualifications: A levels/AS levels or equivalent 1.59 11 8 24.2 0.33 2.8e-01 ABCB9 GPD2 LRRC37A MPHOSPH9 NRBF2 OGFOD2 RNF123 SBNO1 SETD8 SUOX UQCC
Mouth/teeth dental problems: Dentures 1.27 2 1 3.0 0.00 1.0e+00 MUC1 PSMA4
Asthma 1.70 13 8 24.2 0.11 6.8e-01 AC034220.3 AHI1 HTR4 IQCH LIME1 MAP2K5 P4HA2 PNMT RP11-574K11.5 SLC22A5 STMN3 SUOX ZGPAT
Medication: Cholesterol lowering 1.24 3 0 0.0 0.00 1.0e+00 NOP58 OPRL1 SIDT2
Lung cancer (father) 1.27 1 1 3.0 0.00 1.0e+00 PSMA4
Forced expiratory volume in 1-second (FEV1), Best measure 4.48 104 72 218.2 -0.92 2.5e-47 ABLIM3 AC073834.3 AHI1 ANAPC10 ANGPTL1 AOC1 AP4E1 ARFGEF2 ARFRP1 ARL17B ASPSCR1 BOK BRAF BTBD1 C10orf11 C1GALT1 C6orf106 CACFD1 CALML6 CAMK1D CD79B CDC123 CENPW CEP120 CLUAP1 COG4 CRIM1 CTA-85E5.10 CTB-36H16.2 CTD-2323K18.1 CTSS DARS DCAF16 DCXR DHDDS DLG1 DPP3 EBPL EEF1G EFEMP1 EML3 GANAB GOLGA6L9 HSPA4 HTR4 INTS12 IPO8 JAG1 LLGL2 LONRF2 LRPAP1 LRRC37A LRRIQ1 LTBP4 MCM6 MDM4 MICAL3 MRPL21 MST1P2 MYADML2 NFAT5 NOB1 NQO1 NSF OSM PAIP1 PDE12 PDIK1L PLAGL2 PLCD3 PNMT PRDM11 PSMA4 PTCH1 PYGB QSOX2 RAB3IL1 RIN3 RNF123 ROM1 RP1-137D17.1 RP11-449D8.5 RP11-538P18.2 RP11-574K11.5 RP11-967K21.1 SCMH1 SEC24C SH3RF1 SMG7 SMPD2 SMURF2 SNAI3-AS1 SOGA2 STX1B SUOX TBC1D30 TBX3 TCP11 TULP4 UBXN2A ZBTB38 ZCCHC24 ZGPAT ZMAT2
Impedance of arm (left) 1.61 54 40 121.2 0.22 1.0e-01 AOC1 ARL17B BOP1 C18orf8 CALML6 CENPW CEP120 CTD-3232M19.2 CTSS DIP2B EEF1G EFEMP1 EML3 ERGIC3 FOXO3 GANAB GGT7 GS1-393G12.12 HECTD4 HLX KM-PA-2 LIN28B LRRC37A LTBP1 MAP1LC3A MLLT10 MST1P2 MTA2 MUC1 NCOA6 NOL8 NRBF2 NSF NUFIP2 OLFM2 PIAS1 PNMAL1 RALY RIN3 RMI1 RNF123 RNF185 ROM1 RP11-529H20.5 RPS20 SAMD4A SCMH1 SEMA3B-AS1 SLC2A4RG SLC9A3R2 STX1B SUOX TFG ZNF641
Arm fat mass (right) 1.72 39 28 84.8 0.69 5.0e-07 ARFRP1 C18orf8 C6orf106 CCDC171 CCNT2 CDK5RAP3 CEP120 CLUAP1 CRIM1 CWC27 DLG4 EIF3C FOXO3 GGT7 HINT1 HTR4 IQCH KIAA1598 MAP1LC3A MAP2K5 MCM6 MLLT10 NCOA6 NOB1 NR2F1 NR3C1 PYGB RALY RNF123 RP11-613D13.5 RP11-6N17.9 RP1-283E3.4 SLC9A3R2 STX1B SUOX TCP11 UQCC ZBTB38 ZNF654
Trunk predicted mass 3.22 89 70 212.1 0.31 1.2e-03 ABCB9 AC034220.3 AC062029.1 ANAPC10 AOC1 ARFGEF2 B3GNT7 BOK C18orf8 C6orf106 CALML6 CCDC91 CD79B CENPW CEP120 CEP250 CHP CHRNB1 CNIH4 CNTROB COPS7B CRIM1 CRLF3 CTC-228N24.3 CTD-2323K18.1 DCAF16 DHDDS DNA2 DOT1L EBPL EFEMP1 EIF2AK4 EIF4E2 ERGIC3 FBXW8 FOXO3 GGT7 GSS HECTD4 HINT1 IPO8 KIAA1598 LIN28B MAP1LC3A MPHOSPH9 MRPL21 MST1P2 MUC1 NCOA6 NR3C1 NUDT6 OGFOD2 OMG P4HA2 PARK7 PBLD PDIK1L PNMAL1 PTCH1 QSOX2 RAB7L1 RALY RIN3 RNF123 RP11-332H18.4 RP11-477D19.2 RP11-529H20.5 RP11-613D13.5 RP11-967K21.1 RPS20 SBNO1 SCMH1 SDCCAG3 SENP6 SETD8 SLC25A5P1 SLC9A3R2 SMPD2 SNAI3-AS1 SNX13 SUOX TBC1D30 TEFM UBXN2A UQCC ZBTB38 ZBTB4 ZMAT2 ZNF654
Standing height 3.84 144 120 363.6 0.31 7.7e-05 ABCB9 AC034220.3 AC062029.1 ACTG1 ALDH6A1 ANAPC10 AOC1 ARFGEF2 ASPSCR1 B3GNT7 BOK BOP1 BRAF C18orf8 C6orf106 CA14 CACFD1 CCDC126 CCDC91 CD79B CDK2AP1 CDK5RAP3 CENPW CEP120 CEP250 CEP63 CHP CHRNB1 CNIH4 CNTROB COG4 COPS7B CPZ CRIM1 CRLF3 CTC-228N24.3 CTD-2323K18.1 CTD-3232M19.2 CYTL1 DCAF16 DCXR DIP2B DISP2 DNA2 DOT1L DYNLL1-AS1 EBPL EFEMP1 EIF2AK4 EIF4E2 ERC1 ERGIC3 FAM136A FBXW8 FLI1 FOXO3 GGT7 GLB1 GRK4 GSS HECTD4 HINT1 HLX HM13 IPO8 JAG1 KIAA1875 KM-PA-2 LIN28B LLGL2 LRRC37A LTBP1 MAP1LC3A MCM4 MPHOSPH9 MRPS35 MRPS6 MST1P2 MYADML2 MYO6 NCOA6 NDUFB2-AS1 NFAT5 NOB1 NOL8 NOP58 NPC2 NR3C1 NSF NUDT6 OGFOD2 OMG P4HA2 PARK7 PBLD PDIK1L PIEZO1 PLCD3 PROSER2 PTCH1 QSOX2 RAB7L1 RALY RBBP8 RMI1 RP11-171I2.2 RP11-332H18.4 RP11-477D19.2 RP11-529H20.5 RP11-538P18.2 RP11-6N17.10 RP11-860B13.1 RP11-967K21.1 RPS20 RRP15 SAMD4A SBNO1 SCMH1 SDCCAG3 SEMA3B-AS1 SENP6 SETD8 SF3B2 SLC22A5 SLC2A9 SLC9A3R2 SMPD2 SMURF2 SNAI3-AS1 SNX13 STRA13 SUSD5 TBC1D30 TEFM TMTC4 TRAF3IP1 TSEN2 TULP4 UBXN2A UQCC WFIKKN1 ZBTB38 ZBTB4 ZNF641
Exposure to tobacco smoke at home 1.13 1 0 0.0 0.00 1.0e+00 RNF123
Tense / 'highly strung' 1.17 2 0 0.0 0.00 1.0e+00 SEMA3B-AS1 STX1B
Seen doctor (GP) for nerves, anxiety, tension or depression 1.26 1 1 3.0 0.00 1.0e+00 TCF4
Hair/balding pattern: Pattern 4 2.14 13 9 27.3 -0.35 2.2e-01 ARL17B C10orf11 CENPW CTB-36H16.2 DIP2B FAM136A GSS LRRC37A NSF SMG6 SUPT3H TWIST1 ZBTB38
Birth weight of first child 1.78 10 5 15.2 -0.54 5.5e-02 ANAPC10 ASPSCR1 CTC-228N24.3 DCAF16 DCXR DLG4 HECTD4 IPO8 SLC12A2 ZBTB38
Peak expiratory flow (PEF) 2.55 36 20 60.6 -0.49 1.4e-03 ANAPC10 ASPSCR1 BMP4 BOK C10orf11 C1GALT1 CACFD1 CAMK1D CD79B CDC123 CEP250 CTA-85E5.10 DCAF16 DLG1 DLG4 DPP3 EBPL EFEMP1 ERGIC3 GSS HTR4 LRRC37A LRRIQ1 MAP1LC3A MDM4 MYADML2 NCOA6 NR2F1 NSF RAB7L1 RNF123 SF3B2 SMPD2 TMEM194B TNFAIP8 UQCC
Qualifications: O levels/GCSEs or equivalent 1.30 5 3 9.1 0.98 3.3e-03 ABCB9 MPHOSPH9 OGFOD2 SBNO1 SETD8
Blood clot in the leg (DVT) 1.43 2 1 3.0 0.00 1.0e+00 AC113189.5 CACFD1
Medication: Paracetamol 1.41 3 1 3.0 0.99 1.1e-02 LRRC37A MLLT10 NSF
Headache pain in last month 1.40 4 3 9.1 0.81 9.3e-02 AFF1 ARL17B LRRC37A NSF
Medication for cholesterol, blood pressure or diabetes 1.33 2 1 3.0 0.00 1.0e+00 OPRL1 SIDT2
Gout (self-reported) 1.14 2 1 3.0 0.00 1.0e+00 MUC1 SLC2A9
Hypothyroidism/myxoedema (self-reported) 1.25 5 3 9.1 0.59 3.0e-01 AHI1 HECTD4 SBNO1 SETD8 SUOX
Medication: Amlodipine 1.28 1 0 0.0 0.00 1.0e+00 CHRNB1
Medication: Ventolin 100micrograms inhaler 1.23 1 0 0.0 0.00 1.0e+00 SUOX
Birth weight 1.64 11 5 15.2 0.08 8.2e-01 ANAPC10 CENPW CTA-85E5.10 DCAF16 DLG4 DNA2 HECTD4 PTCH1 RAB7L1 TCP11 TEFM
Chronic bronchitis/emphysema (mother) 1.40 1 1 3.0 0.00 1.0e+00 PSMA4
High blood pressure (siblings) 1.27 2 0 0.0 0.00 1.0e+00 HECTD4 STX1B
Forced vital capacity (FVC), Best measure 4.86 142 86 260.6 -0.91 2.4e-60 ABLIM3 AC073834.3 AC104532.4 AHI1 ANAPC10 ANGPTL1 AOC1 AP4E1 ARFGEF2 ARFRP1 ARID3B ARL17B ASPSCR1 BCDIN3D BMF BOK BRAF BTBD1 C10orf11 C1GALT1 C2orf54 CACFD1 CAMK1D CARF CCDC126 CCDC171 CD79B CDC123 CENPW CEP120 CERS2 CFHR3 CLUAP1 COG4 CPE CRIM1 CTA-85E5.10 CTB-36H16.2 CTC-228N24.3 CTD-2323K18.1 CTD-3184A7.4 CTSS CUL3 DARS DCAF16 DCXR DHDDS DLG1 DPP3 EBPL EEF1G EFEMP1 EIF2AK4 EML3 EPB41L2 ERC1 EYA2 FAM136A GANAB GOLGA6L9 HTR4 INTS12 IPO8 JAG1 LONRF2 LRPAP1 LRRC37A LRRIQ1 LTBP4 MCM6 MDM4 METTL22 MICAL3 MLLT10 MRPL21 MRPS35 MST1P2 MUC1 MYADML2 NDUFB2-AS1 NFAT5 NNT NOB1 NOP58 NOX4 NQO1 NSF OSM PDE12 PDIK1L PELI3 PLCD3 PLXNA1 PNMT PRDM11 PSMA4 PTCH1 PYGB QSOX2 RAB3IL1 RIN3 RNASEH2C RNF123 ROM1 RP11-250B2.6 RP11-316M1.12 RP1-137D17.1 RP11-422P24.10 RP11-449D8.5 RP11-538P18.2 RP11-568A19.1 RP11-574K11.5 RP11-613D13.5 RP11-967K21.1 RP1-283E3.4 RPS20 RRP15 SCMH1 SEC24C SF3B2 SHROOM3 SLC12A2 SLC2A4RG SMG7 SMPD2 SMURF2 SNAI3-AS1 STMN3 STX1B SUOX SUSD5 TBC1D30 TCP11 TULP4 UBXN2A UQCC WDR18 ZBTB38 ZCCHC24 ZGPAT ZMAT2 ZNF438
Body fat percentage 1.98 46 27 81.8 0.69 1.9e-08 AC073834.3 ARFGEF2 ARFRP1 C18orf8 C6orf106 CCDC171 CCNT2 CD79B CDK5RAP3 CENPW CRIM1 CTC-228N24.3 CTSS CWC27 DARS DCAF16 DLG1 DNA2 EIF3C FOXO3 HTR4 IQCH KIAA1598 LIME1 MAP2K5 MCM6 MLLT10 MRPS21 NOB1 NSF PYGB RIN3 RNF123 RP11-613D13.5 RP11-6N17.9 RP1-283E3.4 RPRD2 SLC2A4RG SLC9A3R2 ST7L STMN3 STX1B TCP11 ZBTB38 ZGPAT ZNF654
Leg fat percentage (right) 2.16 43 26 78.8 0.71 2.1e-08 AC073834.3 ARFGEF2 ARFRP1 C18orf8 C6orf106 CARF CCDC171 CCNT2 CD79B CENPW CTC-228N24.3 CTD-3184A7.4 CWC27 DARS DCAF16 DLG1 DLG4 DNA2 EIF3C HTR4 IQCH KIAA1598 LIME1 MAP2K5 MCM6 MLLT10 MRPS21 NOB1 PYGB RIN3 RNF123 RP11-613D13.5 RP1-283E3.4 RPRD2 SLC12A2 SLC2A4RG SNAI3-AS1 STMN3 STX1B TCP11 UQCC ZCCHC24 ZNF654
Arm fat-free mass (right) 2.87 81 60 181.8 0.38 2.0e-04 ABCB9 AC034220.3 AC062029.1 ANAPC10 AOC1 ARFGEF2 BOK C18orf8 C6orf106 CALML6 CCDC91 CD79B CENPW CEP120 CEP250 CHP CHRNB1 CNIH4 COPS7B CRIM1 CRLF3 CTD-2323K18.1 DCAF16 DHDDS DNA2 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C EIF4E2 ERGIC3 FOXO3 GGT7 GSS HECTD4 HINT1 IPO8 KIAA1598 MAP1LC3A MLLT10 MPHOSPH9 MRPL21 MUC1 NCOA6 NR3C1 NUDT6 OGFOD2 OMG P4HA2 PARK7 PBLD PDIK1L PNMAL1 PTCH1 RAB7L1 RALY RIN3 RNF123 RP11-332H18.4 RP11-613D13.5 RP11-967K21.1 RPS20 SCMH1 SDCCAG3 SENP6 SETD8 SLC25A5P1 SLC9A3R2 SMPD2 SNX13 STX1B SUOX TBC1D30 TEFM UBXN2A UQCC ZBTB38 ZBTB4 ZMAT2 ZNF654
Exposure to tobacco smoke outside home 1.26 1 0 0.0 0.00 1.0e+00 NRBF2
Comparative body size at age 10 1.47 15 10 30.3 -0.15 5.9e-01 ATP6V0D1 BCDIN3D CLUAP1 DOT1L EIF3C IQCH LIN28B MAP2K5 RAB7L1 SEMA3B-AS1 SMG6 ST7L STX1B ZNF641 ZNF654
Worry too long after embarrassment 1.16 4 1 3.0 0.32 6.8e-01 AHI1 BCDIN3D IQCH LRRC37A
Wheeze or whistling in the chest in last year 1.60 9 3 9.1 0.97 3.2e-06 ARFRP1 BTBD7 CCDC171 CTD-3184A7.4 LIME1 RNF123 STMN3 STX1B ZGPAT
Age at first live birth 1.22 4 1 3.0 -0.51 4.9e-01 KIAA1598 NRBF2 RNF123 SUOX
Health satisfaction 1.24 1 0 0.0 0.00 1.0e+00 RNF123
Qualifications: College or University degree 1.65 23 20 60.6 -0.11 5.9e-01 ABCB9 B3GNT1 BCDIN3D C18orf8 CLUAP1 DNA2 EIF3C FOXO3 GRK4 KIFC2 LRRC37A MDM4 MPHOSPH9 NRBF2 NSF OGFOD2 RIN1 RNF123 RP11-1084E5.1 SBNO1 SETD8 SUOX TIGD2
Mouth/teeth dental problems: Loose teeth 1.28 2 2 6.1 -0.99 1.1e-03 CCDC91 RP11-967K21.1
Medication for pain relief, constipation, heartburn 1.40 4 1 3.0 -0.20 7.5e-01 C6orf106 LRRC37A MPHOSPH9 PLCD3
Medication: Blood pressure 1.38 2 0 0.0 0.00 1.0e+00 DLG4 HECTD4
Angina (self-reported) 1.32 1 0 0.0 0.00 1.0e+00 GGT7
Medication: Allopurinol 1.17 2 1 3.0 0.00 1.0e+00 MUC1 SLC2A9
Mean time to correctly identify matches 1.19 8 3 9.1 -0.02 9.6e-01 ARFGEF2 DLG4 FOXO3 HECTD4 RAB7L1 RMI1 TOM1L2 WFIKKN1
Whole body fat mass 1.91 44 33 100.0 0.65 7.3e-07 ANAPC10 ARFRP1 C18orf8 C6orf106 CCDC171 CDK5RAP3 CEP120 CEP250 CRIM1 CTD-2201E18.3 CWC27 DLG1 EFEMP1 EIF3C ERGIC3 FOXO3 GGT7 HINT1 HTR4 IQCH KIAA1598 LIME1 MAP1LC3A MAP2K5 MCM6 MLLT10 MRPS21 NCOA6 NOB1 NR3C1 PCYT1A PYGB RNF123 RP11-613D13.5 RP11-6N17.9 RP1-283E3.4 SLC2A4RG SLC9A3R2 STMN3 STX1B TCP11 UQCC ZBTB38 ZNF654
Leg fat mass (right) 1.80 38 26 78.8 0.72 2.1e-07 ARFRP1 C18orf8 C6orf106 CCDC171 CCNT2 CDK5RAP3 CEP120 CRIM1 CTC-228N24.3 CTD-2201E18.3 CTD-3184A7.4 CWC27 EIF3C FOXO3 GGT7 HINT1 HTR4 IQCH KIAA1598 LIME1 MAP1LC3A MAP2K5 MCM6 MLLT10 MRPS21 NCOA6 NOB1 PCYT1A PYGB RALY RNF123 RP11-613D13.5 RP1-283E3.4 SLC9A3R2 STX1B TCP11 ZBTB38 ZNF654
Arm predicted mass (right) 2.85 82 60 181.8 0.40 9.0e-05 ABCB9 AC034220.3 AC062029.1 ANAPC10 AOC1 ARFGEF2 B3GNT7 BOK C18orf8 C6orf106 CALML6 CCDC91 CD79B CENPW CEP120 CEP250 CHP CHRNB1 CNIH4 COPS7B CRIM1 CRLF3 CTD-2323K18.1 DCAF16 DHDDS DNA2 DOT1L EBPL EFEMP1 EIF3C EIF4E2 ERGIC3 FOXO3 GGT7 GSS HECTD4 HINT1 IPO8 KIAA1598 MAP1LC3A MLLT10 MPHOSPH9 MRPL21 MUC1 NCOA6 NR3C1 NUDT6 OGFOD2 OMG P4HA2 PARK7 PBLD PCYT1A PDIK1L PNMAL1 PTCH1 RAB7L1 RALY RIN3 RNF123 RP11-332H18.4 RP11-613D13.5 RP11-967K21.1 RPS20 SCMH1 SDCCAG3 SENP6 SETD8 SLC25A5P1 SLC9A3R2 SMPD2 SNX13 STX1B SUOX TBC1D30 TEFM UBXN2A UQCC ZBTB38 ZBTB4 ZMAT2 ZNF654
Pulse rate, automated reading 1.45 16 11 33.3 0.65 6.4e-03 B3GNT7 BTBD1 C6orf106 CCDC58 CD55 CEP120 DARS EEF1G EML3 GANAB MSH6 PDIK1L RNASEH2C TMEM194B TOM1L2 ZBTB38
Alcohol intake frequency. 1.39 10 6 18.2 0.41 2.1e-01 ADH1B C18orf8 CDADC1 EIF3C LRRC37A NOA1 NSF SETD8 SMPD2 TCF4
Comparative height size at age 10 3.48 94 70 212.1 0.30 1.8e-03 ABCB9 AC034220.3 AC062029.1 ANAPC10 AOC1 ARFGEF2 ASPSCR1 B3GNT7 BCDIN3D BOK C18orf8 C6orf106 CCDC126 CCDC91 CD79B CDK2AP1 CENPW CEP120 CEP250 CEP63 CHRNB1 CNIH4 CNTROB COPS7B CPE CRIM1 CRLF3 CTD-3232M19.2 DCAF16 DNA2 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C EIF4E2 ERGIC3 FLI1 FOXO3 GGT7 GSS HECTD4 HINT1 IQCH KIAA1875 KM-PA-2 LRRC37A MAP1LC3A MICAL3 MPHOSPH9 MRPS6 MST1P2 MYADML2 MYO6 NCOA6 NR3C1 NSF OGFOD2 OMG P4HA2 PBLD PDIK1L PIEZO1 PLCD3 PTCH1 QSOX2 RAB7L1 RBBP8 RMI1 RP11-171I2.2 RP11-332H18.4 RP11-378A13.1 RP11-477D19.2 RP11-529H20.5 RP11-967K21.1 RP1-199J3.5 RPS20 SBNO1 SCMH1 SDCCAG3 SENP6 SETD8 SLC2A9 SLC9A3R2 SMPD2 SUSD5 TCF4 TEFM TRAF3IP1 UBXN2A UQCC WFIKKN1 ZBTB38 ZBTB4
Suffer from 'nerves' 1.07 1 0 0.0 0.00 1.0e+00 EIF3C
Overall health rating 1.48 8 3 9.1 0.96 2.0e-04 C6orf106 DCAF16 DPP3 GRK4 HTR4 PELI3 RNF123 STX1B
Age at last live birth 1.03 1 1 3.0 0.00 1.0e+00 RNF123
Knee pain experienced in last month 1.46 4 3 9.1 -0.72 2.8e-01 CEP250 ERGIC3 STX1B UQCC
Hypertension (Self-reported) 1.52 17 8 24.2 0.20 4.2e-01 AC034220.3 C1GALT1 CHP DCAF16 DLG4 GMEB2 HECTD4 HTR4 MAP2K5 MRAS OPRL1 RP11-332H18.4 RP11-538P18.2 SLC12A2 STX1B VAC14-AS1 ZNF641
Illnesses of siblings: Diabetes 1.33 1 1 3.0 0.00 1.0e+00 CAMK1D
Smoking status: Previous 1.45 1 0 0.0 0.00 1.0e+00 MSH6
Forced expiratory volume in 1-second (FEV1), predicted 2.65 35 25 75.8 0.41 9.1e-03 AC034220.3 ANAPC10 BOK C18orf8 C6orf106 CCDC91 CD79B CENPW CEP250 CHRNB1 CNIH4 CRLF3 DCAF16 DOT1L EBPL EFEMP1 ERGIC3 GGT7 LIN28B LTBP1 MAP1LC3A MST1P2 NCOA6 P4HA2 PTCH1 RP11-332H18.4 RP11-529H20.5 RP11-967K21.1 SCMH1 SDCCAG3 SEMA3B-AS1 TEFM UQCC ZBTB38 ZBTB4
Whole body fat-free mass 3.06 87 72 218.2 0.30 2.4e-03 ABCB9 AC034220.3 AC062029.1 ANAPC10 AOC1 ARFGEF2 B3GNT7 BOK C18orf8 C6orf106 CALML6 CCDC91 CD79B CENPW CEP120 CEP250 CHP CHRNB1 CNIH4 COPS7B CRIM1 CRLF3 CTA-85E5.10 CTC-228N24.3 CTD-2323K18.1 DCAF16 DHDDS DNA2 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C EIF4E2 ERGIC3 FOXO3 GGT7 GSS HECTD4 HINT1 IPO8 KIAA1598 LIN28B MAP1LC3A MPHOSPH9 MRPL21 MUC1 NCOA6 NR3C1 NUDT6 OGFOD2 OMG P4HA2 PARK7 PBLD PDIK1L PNMAL1 PTCH1 QSOX2 RAB7L1 RALY RIN3 RNF123 RP11-332H18.4 RP11-613D13.5 RP11-967K21.1 RPS20 SBNO1 SCMH1 SDCCAG3 SENP6 SETD8 SLC12A2 SLC25A5P1 SLC9A3R2 SMPD2 SNAI3-AS1 SNX13 STX1B SUOX TEFM UBXN2A UQCC ZBTB38 ZBTB4 ZMAT2 ZNF654
Leg fat-free mass (right) 2.86 82 58 175.8 0.22 3.1e-02 ABCB9 AC004540.4 AC034220.3 AC062029.1 ACTG1 ANAPC10 AOC1 ARFGEF2 BOK C18orf8 C6orf106 CALML6 CD79B CDK5RAP3 CENPW CEP120 CEP250 CHRNB1 CLUAP1 CNIH4 COPS7B CRIM1 CRLF3 CTA-85E5.10 CTC-228N24.3 DCAF16 DHDDS DNA2 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C ERGIC3 FOXO3 GGT7 GLB1 GSS HECTD4 HINT1 IPO8 KIAA1598 MAP1LC3A MAP2K5 MPHOSPH9 MRPL21 MUC1 NCOA6 NR2F1 NR3C1 NUDT6 OGFOD2 OMG P4HA2 PARK7 PBLD PDIK1L PTCH1 QSOX2 RAB7L1 RALY RIN3 RNF123 RP11-332H18.4 RP11-613D13.5 RP11-90P5.2 RP11-967K21.1 RPS20 SCMH1 SETD8 SLC12A2 SLC9A3R2 SMPD2 SMURF2 SNAI3-AS1 STX1B SUOX SUPT3H TEFM UQCC ZBTB38 ZNF654
Arm fat percentage (left) 1.76 38 21 63.6 0.60 3.7e-05 ARFGEF2 ARFRP1 C18orf8 C6orf106 CARF CCDC171 CCNT2 CD79B CDK5RAP3 CENPW CHRNB1 CRIM1 CWC27 DCAF16 DLG1 DLG4 DPP3 EIF3C GRK4 HTR4 IQCH KIAA1598 MAP2K5 MCM6 MLLT10 NFAT5 NOB1 NOP58 PYGB RNF123 RP11-613D13.5 RP11-6N17.9 RP11-967K21.1 RP1-283E3.4 SLC2A4RG STX1B TCP11 ZNF654
Average weekly red wine intake 1.46 5 2 6.1 0.31 6.1e-01 B3GNT1 C18orf8 NRBF2 OGFOD2 SETD8
Handedness (chirality/laterality): Left-handed 1.31 4 2 6.1 -0.60 4.0e-01 ARL17B LRRC37A MAP2 NSF
Mood swings 1.43 5 5 15.2 0.72 1.1e-01 DCC LRRC37A NSF RNF123 TCF4
Long-standing illness, disability or infirmity 1.69 5 1 3.0 0.96 1.1e-02 CCDC171 MRAS NR2F1 RNF123 ZGPAT
Diabetes diagnosed by doctor 1.69 4 2 6.1 0.53 4.7e-01 C1GALT1 CAMK1D CENPW ZCCHC24
Qualifications: nursing, teaching 1.36 4 1 3.0 1.00 3.6e-03 ABCB9 MPHOSPH9 OGFOD2 SETD8
Mouth/teeth dental problems: Mouth ulcers 1.32 4 2 6.1 0.70 1.9e-01 ARL17B CTSS LRRC37A NSF
Back pain experienced in last month 1.20 1 0 0.0 0.00 1.0e+00 C6orf106
Asthma (self-reported) 1.71 11 9 27.3 -0.10 7.4e-01 AC034220.3 AHI1 HTR4 IQCH MAP2K5 P4HA2 PNMT RP11-574K11.5 SLC22A5 STMN3 SUOX
Smoking status: Current 1.48 3 1 3.0 0.00 1.0e+00 ARFRP1 CARF NUFIP2
Forced expiratory volume in 1-second (FEV1), predicted percentage 4.76 59 31 93.9 -0.96 3.7e-36 ALDH6A1 ANGPTL1 ARFRP1 ARL17B ASPSCR1 BOK BTBD1 C10orf11 CAMK1D CCDC91 CDC123 CEP120 CEP63 CLIC6 CLUAP1 CTA-85E5.10 CTD-3184A7.4 CTSS DHDDS EEF1G EML3 GANAB GOLGA6L9 HM13 HTR4 INTS12 JAG1 LIME1 LLGL2 LRRC37A MAP2 MICAL3 MTA2 NNT NOB1 NSF OSM PDE12 PDIK1L PLAGL2 PNMT PSMA4 PYGB QSOX2 RIN3 RNF123 ROM1 RP11-538P18.2 RP11-541N10.3 RP11-967K21.1 SEC24C SLC2A4RG SOGA2 STMN3 STX1B TCP11 UQCC ZGPAT ZSWIM7
Whole body water mass 3.04 87 72 218.2 0.30 2.2e-03 ABCB9 AC034220.3 AC062029.1 ANAPC10 AOC1 ARFGEF2 B3GNT7 BOK C18orf8 C6orf106 CALML6 CCDC91 CD79B CENPW CEP120 CEP250 CHP CHRNB1 CNIH4 COPS7B CRIM1 CRLF3 CTA-85E5.10 CTC-228N24.3 CTD-2323K18.1 DCAF16 DHDDS DNA2 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C EIF4E2 ERGIC3 FOXO3 GGT7 GSS HECTD4 HINT1 IPO8 KIAA1598 MAP1LC3A MPHOSPH9 MRPL21 MUC1 NCOA6 NR3C1 NUDT6 OGFOD2 OMG P4HA2 PARK7 PBLD PDIK1L PNMAL1 PTCH1 QSOX2 RAB7L1 RALY RIN3 RNF123 RP11-332H18.4 RP11-613D13.5 RP11-967K21.1 RPS20 SBNO1 SCMH1 SDCCAG3 SENP6 SETD8 SLC12A2 SLC25A5P1 SLC9A3R2 SMPD2 SNAI3-AS1 SNX13 STX1B SUOX SUPT3H TEFM UBXN2A UQCC ZBTB38 ZBTB4 ZMAT2 ZNF654
Leg predicted mass (right) 2.86 83 58 175.8 0.23 2.3e-02 ABCB9 AC034220.3 AC062029.1 ACTG1 ANAPC10 AOC1 ARFGEF2 BOK C18orf8 C6orf106 CALML6 CD79B CDK5RAP3 CENPW CEP120 CEP250 CHRNB1 CLUAP1 CNIH4 COPS7B CRIM1 CRLF3 CTA-85E5.10 CTC-228N24.3 DCAF16 DHDDS DNA2 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C ERGIC3 FOXO3 GGT7 GLB1 GSS HECTD4 HINT1 IPO8 KIAA1598 MAP1LC3A MAP2K5 MPHOSPH9 MRPL21 MUC1 NCOA6 NR2F1 NR3C1 NUDT6 OGFOD2 OMG P4HA2 PARK7 PBLD PDIK1L PNMAL1 PTCH1 RAB7L1 RALY RIN3 RNF123 RP11-332H18.4 RP11-613D13.5 RP11-90P5.2 RP11-967K21.1 RPS20 SCMH1 SETD8 SLC12A2 SLC9A3R2 SMPD2 SMURF2 SNAI3-AS1 STX1B SUOX SUPT3H TEFM UQCC ZBTB38 ZBTB4 ZMAT2 ZNF654
Arm fat mass (left) 1.72 38 27 81.8 0.71 3.3e-07 ARFRP1 BTBD7 C18orf8 C6orf106 CCDC171 CCNT2 CDK5RAP3 CEP120 CLUAP1 CRIM1 CWC27 DLG4 EIF3C FOXO3 GGT7 HINT1 HTR4 IQCH KIAA1598 MAP1LC3A MAP2K5 MCM6 MLLT10 NCOA6 NOB1 NR2F1 PYGB RALY RNF123 RP11-613D13.5 RP11-6N17.9 RP1-283E3.4 SLC9A3R2 STX1B TCP11 UQCC ZBTB38 ZNF654
Number of self-reported non-cancer illnesses 1.64 5 2 6.1 0.11 8.6e-01 HECTD4 IQCH MAP2K5 OPRL1 RNF123
Average weekly champagne plus white wine intake 1.23 1 0 0.0 0.00 1.0e+00 LRRC37A
Miserableness 1.26 4 3 9.1 0.90 3.9e-02 LRRC37A NSF RNF123 TCF4
Guilty feelings 1.29 3 1 3.0 0.55 4.5e-01 LIN28B LRRC37A UBXN2A
Financial situation satisfaction 1.15 1 0 0.0 0.00 1.0e+00 RNF123
Commuting to job workplace: Public transport 1.24 1 0 0.0 0.00 1.0e+00 HM13
Medication: Blood pressure 1.49 9 5 15.2 -0.01 9.9e-01 AC034220.3 C1GALT1 CHP GMEB2 HECTD4 LRRC37A MRAS P4HA2 ZGPAT
Supplements: Fish oil (including cod liver oil) 1.28 2 0 0.0 0.00 1.0e+00 NFAT5 PELI3
High cholesterol (Self-reported) 1.50 6 3 9.1 0.67 1.4e-01 CARF CLCNKA NOP58 OPRL1 SIDT2 TSEN2
Medication: Bendroflumethiazide 1.33 2 0 0.0 0.00 1.0e+00 AC034220.3 P4HA2
Medication: Paracetamol 1.29 2 1 3.0 0.00 1.0e+00 LRRC37A NSF
Ever smoked 1.36 3 1 3.0 0.61 3.9e-01 MSH6 PSMA4 ZFHX3
Basal metabolic rate 2.88 82 67 203.0 0.33 1.2e-03 ABCB9 AC004540.4 AC034220.3 AC062029.1 ANAPC10 AOC1 ARFGEF2 BOK C18orf8 C6orf106 CALML6 CCDC91 CD79B CDK5RAP3 CENPW CEP120 CEP250 CHRNB1 CNIH4 COPS7B CRIM1 CRLF3 CTC-228N24.3 CTD-2323K18.1 DCAF16 DNA2 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C EIF4E2 ERGIC3 FOXO3 GGT7 GSS HECTD4 HINT1 IPO8 IQCH KIAA1598 MAP1LC3A MAP2K5 MPHOSPH9 MRPL21 MUC1 NCOA6 NR3C1 NUDT6 OGFOD2 OMG P4HA2 PARK7 PBLD PDIK1L PNMAL1 PTCH1 RAB7L1 RALY RIN3 RNF123 RP11-332H18.4 RP11-613D13.5 RP11-967K21.1 RPS20 SCMH1 SDCCAG3 SENP6 SETD8 SLC12A2 SLC25A5P1 SLC9A3R2 SMPD2 STX1B SUOX TEFM UBXN2A UQCC ZBTB38 ZBTB4 ZMAT2 ZNF654
Leg fat percentage (left) 2.17 43 31 93.9 0.69 4.5e-08 AC073834.3 ARFGEF2 ARFRP1 C18orf8 C6orf106 CARF CCDC171 CCNT2 CD79B CENPW CTC-228N24.3 CTD-3184A7.4 CWC27 DARS DCAF16 DLG1 DNA2 EIF3C FOXO3 HTR4 IQCH KIAA1598 LIME1 MAP2K5 MCM6 MLLT10 MPHOSPH9 NOB1 PYGB RIN3 RNF123 RP11-613D13.5 RP1-283E3.4 SLC12A2 SLC2A4RG SLC9A3R2 STMN3 STX1B TCP11 UQCC ZCCHC24 ZGPAT ZNF654
Arm fat-free mass (left) 2.87 75 60 181.8 0.41 9.6e-05 ABCB9 AC034220.3 ANAPC10 AOC1 ARFGEF2 BOK C18orf8 C6orf106 CALML6 CCDC91 CD79B CENPW CEP120 CEP250 CHRNB1 CNIH4 COPS7B CRIM1 CRLF3 CTD-2323K18.1 DCAF16 DHDDS DOT1L EBPL EFEMP1 EIF2AK4 EIF3C EIF4E2 ERGIC3 FOXO3 GGT7 GSS HECTD4 HINT1 KIAA1598 MAP1LC3A MLLT10 MPHOSPH9 MRPL21 MUC1 NCOA6 NR3C1 NUDT6 OGFOD2 OMG P4HA2 PARK7 PBLD PDIK1L PNMAL1 PTCH1 RAB7L1 RALY RIN3 RNF123 RP11-332H18.4 RP11-613D13.5 RP11-967K21.1 RPS20 SCMH1 SDCCAG3 SENP6 SETD8 SLC25A5P1 SLC9A3R2 SMPD2 SNX13 STX1B SUOX TEFM UBXN2A UQCC ZBTB38 ZBTB4 ZNF654
Number of operations (self-reported) 1.38 3 1 3.0 0.00 1.0e+00 CTC-228N24.3 MLLT10 PARK7
Average weekly beer plus cider intake 1.19 1 0 0.0 0.00 1.0e+00 RNF123
Irritability 1.35 2 2 6.1 0.00 1.0e+00 LRRC37A NSF
Ever had prostate specific antigen (PSA) test 1.31 1 0 0.0 0.00 1.0e+00 ZBTB38
Fractured/broken bones in last 5 years 1.33 2 0 0.0 0.00 1.0e+00 IQCH MAP2K5
Diastolic blood pressure, automated reading 1.60 28 17 51.5 0.19 3.2e-01 ABCB9 ADAMTS8 ANKFY1 ARFRP1 CCNT2 CEP120 CHP DARS DCAF16 DLG4 GMEB2 HECTD4 JAG1 MICAL3 MPHOSPH9 OGFOD2 PDE12 RNF123 RP11-23P13.7 RP11-332H18.4 RP11-538P18.2 SBNO1 SCMH1 SETD8 SMG6 STMN3 STX1B ZGPAT
Myopia 1.40 2 1 3.0 0.00 1.0e+00 BMP4 QSOX2
Vascular/heart problems diagnosed by doctor 1.47 15 10 30.3 -0.12 6.5e-01 AC034220.3 C1GALT1 CHP DCAF16 DLG4 GMEB2 HECTD4 IQCH MAP2K5 MRAS OPRL1 OSM RP11-538P18.2 SLC22A5 STX1B
Cholesterol lowering medication 1.33 5 0 0.0 0.58 3.1e-01 CARF CLCNKA OPRL1 SIDT2 STX1B
Pain experienced in last month 1.29 3 0 0.0 0.00 1.0e+00 CENPW STX1B SUOX
Heart attack/myocardial infarction (self-reported) 1.24 1 0 0.0 0.00 1.0e+00 TOM1L2
Deep venous thrombosis (DVT) (self-reported) 1.41 2 1 3.0 0.00 1.0e+00 AC113189.5 CACFD1
Pack years of smoking 1.67 1 1 3.0 0.00 1.0e+00 PSMA4
Impedance of whole body 1.81 60 46 139.4 0.22 7.6e-02 AOC1 ARL17B CALML6 CENPW CEP120 CLUAP1 CTA-85E5.10 CTC-228N24.3 CTD-3232M19.2 CTSS DHDDS DIP2B EEF1G EFEMP1 EML3 ERGIC3 FOXO3 GANAB GGT7 GS1-393G12.12 HINT1 HLX KM-PA-2 LIN28B LRRC37A LRRN2 LTBP1 MAP1LC3A MRPL21 MST1P2 MTA2 MUC1 NCOA6 NOL8 NRBF2 NSF NUFIP2 OLFM2 PIAS1 PNMAL1 RAB7L1 RALY RIN1 RIN3 RMI1 RNF123 RNF185 RPS20 SCMH1 SEMA3B-AS1 SLC12A2 SLC2A4RG SLC9A3R2 STX1B SUOX SUPT3H TFG UQCC ZNF641 ZNF654
Leg fat mass (left) 1.79 41 26 78.8 0.73 2.0e-08 ARFRP1 BTBD7 C18orf8 C6orf106 CCDC171 CCNT2 CDK5RAP3 CEP120 CRIM1 CTC-228N24.3 CTD-2201E18.3 CTD-3184A7.4 CWC27 DARS DLG1 EIF3C FOXO3 GGT7 HTR4 IQCH KIAA1598 LIME1 MAP1LC3A MAP2K5 MCM6 MLLT10 MRPS21 NCOA6 NOB1 PCYT1A PYGB RALY RNF123 RP11-613D13.5 RP1-283E3.4 SLC9A3R2 STMN3 STX1B TCP11 ZBTB38 ZNF654
Arm predicted mass (left) 2.85 76 61 184.8 0.40 1.0e-04 ABCB9 AC034220.3 ANAPC10 AOC1 ARFGEF2 BOK C18orf8 C6orf106 CALML6 CCDC91 CD79B CENPW CEP120 CEP250 CHP CHRNB1 CNIH4 COPS7B CRIM1 CRLF3 CTD-2323K18.1 DCAF16 DNA2 DOT1L EBPL EFEMP1 EIF2AK4 EIF3C EIF4E2 ERGIC3 FOXO3 GGT7 GSS HECTD4 HINT1 KIAA1598 MAP1LC3A MLLT10 MPHOSPH9 MRPL21 MUC1 NCOA6 NR3C1 NUDT6 OGFOD2 OMG P4HA2 PARK7 PBLD PDIK1L PNMAL1 PTCH1 RAB7L1 RALY RIN3 RNF123 RP11-332H18.4 RP11-613D13.5 RP11-967K21.1 RPS20 SCMH1 SDCCAG3 SENP6 SETD8 SLC25A5P1 SLC9A3R2 SMPD2 STX1B SUOX TEFM UBXN2A UQCC ZBTB38 ZBTB4 ZMAT2 ZNF654

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 108 3.09 5.10
GTEx Adipose Visceral Omentum 76 3.73 5.68
GTEx Adrenal Gland 53 3.64 5.64
GTEx Artery Aorta 104 3.49 5.71
GTEx Artery Coronary 45 3.80 6.43
GTEx Artery Tibial 116 3.09 5.15
GTEx Brain Caudate basal ganglia 30 3.26 5.60
GTEx Brain Cerebellar Hemisphere 52 3.49 6.06
GTEx Brain Cerebellum 80 4.03 5.68
GTEx Brain Cortex 42 4.06 5.94
GTEx Brain Frontal Cortex BA9 30 3.24 5.84
GTEx Brain Hippocampus 18 3.43 6.69
GTEx Brain Hypothalamus 20 3.38 6.26
GTEx Brain Nucleus accumbens basal ganglia 28 3.23 5.92
GTEx Brain Putamen basal ganglia 18 2.88 5.86
GTEx Breast Mammary Tissue 70 3.54 5.74
GTEx Breast Mammary Tissue (Male) 34 2.85 5.97
GTEx Breast Mammary Tissue (Female) 48 2.92 5.31
GTEx Cells EBV-transformed lymphocytes 44 3.10 5.90
GTEx Cells Transformed fibroblasts 149 3.55 5.33
GTEx Colon Sigmoid 35 2.39 5.60
GTEx Colon Transverse 66 3.20 5.63
GTEx Esophagus Gastroesophageal Junction 52 3.60 6.00
GTEx Esophagus Mucosa 121 3.64 5.42
GTEx Esophagus Muscularis 127 3.93 5.77
GTEx Heart Atrial Appendage 62 3.92 6.32
GTEx Heart Left Ventricle 59 3.85 5.71
GTEx Liver 28 3.91 5.94
GTEx Lung 103 3.59 5.58
GTEx Muscle Skeletal 105 3.63 5.44
GTEx Nerve Tibial 146 3.38 5.16
GTEx Ovary 42 4.62 7.03
GTEx Pancreas 51 3.12 5.61
GTEx Pituitary 50 4.48 6.33
GTEx Prostate 27 3.24 5.68
GTEx Skin Not Sun Exposed Suprapubic 85 3.46 5.67
GTEx Skin Sun Exposed Lower leg 134 3.68 5.46
GTEx Small Intestine Terminal Ileum 20 4.33 6.32
GTEx Spleen 56 3.97 5.87
GTEx Stomach 58 3.99 5.99
GTEx Testis 111 3.52 5.32
GTEx Thyroid 148 3.70 5.47
GTEx Uterus 25 4.41 7.13
GTEx Vagina 19 2.99 6.18
GTEx Whole Blood 60 3.02 5.19
METSIM Adipose 111 2.41 4.37
NTR Blood 62 2.58 4.53
ROSMAP Brain Pre-frontal Cortex 105 2.39 4.24
YFS Blood 146 3.16 4.37
CommonMind Brain Pre-frontal Cortex 121 2.25 4.27
TCGA Breast Tumor 27 3.52 5.21
TCGA Breast Normal 97 2.31 4.03
TCGA Ovarian Tumor 59 2.02 4.03
TCGA Prostate Tumor 109 3.15 4.80