Hub : Traits :

Lung FEV1/FVC ratio

3892 significantly associated models · 1081 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 1781220 4040155 3 2 1.1e-11 7.8e-34 1.9e-24 29 ARHGEF16 RP3-395M20.9
2 1 5611729 7460433 7 2 6.5e-19 4.9e-22 NaN NaN DNAJC11 THAP3
3 1 8467353 11222393 4 2 5.7e-09 1.1e-16 9.9e-17 0 GPR157 KIF1B
4 1 15651062 18461490 26 7 5.6e-74 3.9e-75 NaN NaN EPHA2 MFAP2 MST1L MST1P2 NBPF1 PADI2 RP11-108M9.5
5 1 18940380 20503710 2 1 2.9e-11 1.8e-17 1.1e-07 61 CAPZB
6 1 31402148 32762733 1 1 1.9e-10 1.5e-10 1.0e+00 100 PEF1
7 1 36079508 41065744 17 6 3.9e-22 5.7e-19 4.7e-01 99 DNALI1 PABPC4 SH3D21 TRIT1 YRDC
8 1 44779991 48392033 19 4 6.4e-18 2.9e-18 2.5e-03 88 ATPAF1 CYP4B1 MUTYH RP1-18D14.7
9 1 71163715 73435171 1 1 3.6e-09 3.4e-08 7.4e-03 76 NEGR1
10 1 77464831 79534138 6 7 5.7e-16 2.3e-15 1.0e+00 100 DNAJB4 GIPC2 NEXN
11 1 91800946 94294492 6 3 7.2e-24 5.3e-75 1.2e-94 -27 BTBD8 EPHX4 EVI5
12 1 109098737 110517617 2 1 9.5e-09 1.4e-07 1.5e-01 92 CELSR2
13 1 110716511 112953341 7 3 1.4e-25 3.0e-30 1.8e-03 92 DRAM2
14 1 149672809 150600181 2 1 4.4e-11 4.2e-11 1.0e+00 100 MTMR11
15 1 153504759 155924505 2 2 1.8e-07 5.0e-20 2.6e-14 31 C1orf43 SCAMP3
16 1 160851894 162347618 3 1 8.2e-09 2.4e-06 3.3e-05 23 FCGR2B
17 1 168443178 170032254 1 1 3.8e-07 4.6e-06 5.4e-01 98 NME7
18 1 185651973 187084806 1 1 1.8e-09 4.0e-18 1.0e-13 26 C1orf27
19 1 195927451 197414097 1 1 9.1e-08 3.2e-07 1.8e-01 93 CFH
20 1 200740278 202607593 3 2 1.6e-09 1.5e-13 2.2e-07 51 RP11-134G8.8 SHISA4
21 1 203890813 207334619 12 4 2.7e-17 7.3e-18 1.2e-07 62 CNTN2 NUCKS1 SRGAP2
22 1 217760821 219208920 1 2 2.6e-21 1.2e-29 6.4e-18 42 RRP15
23 1 219623621 221136787 1 1 9.2e-08 1.1e-29 3.4e-25 16 RAB3GAP2
24 1 222096959 223537385 2 1 5.0e-09 8.0e-08 4.3e-05 42 RP11-378J18.8
25 2 8649517 10394558 2 2 8.5e-20 4.2e-30 1.8e-05 86 ADAM17 ASAP2
26 2 14610061 16639566 2 1 2.7e-11 4.2e-28 7.7e-21 27 AC113608.1
27 2 17368202 19236850 1 1 2.1e-25 9.1e-47 9.1e-26 47 KCNS3
28 2 24021231 25889403 5 1 9.7e-14 1.8e-12 6.2e-01 100 ADCY3
29 2 28235763 29792216 3 1 1.6e-08 3.7e-08 2.3e-01 95 TRMT61B
30 2 32483593 34480075 2 2 2.3e-07 3.2e-13 3.2e-08 42 LTBP1 RASGRP3
31 2 35883253 37472804 2 2 2.3e-12 5.6e-28 6.5e-11 64 CRIM1
32 2 41701800 44521246 9 8 1.4e-23 3.1e-28 NaN NaN AC010883.5 COX7A2L EML4 FTOP1 MTA3 OXER1
33 2 55401562 56843605 1 1 2.9e-13 3.6e-25 7.9e-15 44 EFEMP1
34 2 60546132 62460013 8 1 9.9e-16 1.7e-12 1.1e-01 95 AHSA2
35 2 64168232 65948898 2 4 5.6e-13 4.2e-16 4.9e-09 48 SERTAD2 SLC1A4
36 2 73005579 74383630 1 1 2.1e-07 7.3e-07 5.2e-01 98 ALMS1-IT1
37 2 85547429 87126250 5 1 4.0e-09 9.3e-09 1.0e+00 100 IMMT
38 2 98714445 101629737 10 2 7.9e-12 3.2e-12 2.2e-01 97 C2orf15 LONRF2
39 2 102274098 103686111 1 1 1.0e-08 4.9e-21 1.3e-17 18 IL18R1
40 2 119497419 121675485 5 2 1.7e-09 2.1e-08 2.1e-01 95 TMEM185B TMEM37
41 2 151570279 153056846 1 1 1.1e-09 7.7e-10 2.1e-01 96 RIF1
42 2 156594333 158165818 1 1 3.2e-07 7.1e-18 1.3e-14 20 GPD2
43 2 159775621 161318004 3 1 9.7e-10 3.3e-08 3.3e-01 97 MARCH7
44 2 171683107 173114238 1 1 4.0e-07 1.0e-09 1.6e-05 50 CYBRD1
45 2 173245680 174820750 1 1 2.5e-09 5.2e-15 8.3e-08 53 MLTK
46 2 176342243 177746117 1 1 8.9e-11 6.3e-11 1.0e+00 100 HOXD-AS1
47 2 186863405 189113345 3 6 1.9e-19 1.7e-20 NaN NaN AC007319.1 CALCRL FAM171B
48 2 197660966 199060970 1 1 4.1e-07 2.0e-07 1.4e-01 92 HSPD1
49 2 203194256 205097250 2 1 3.8e-11 9.0e-08 2.8e-01 96 RAPH1
50 2 205851076 207355354 2 1 6.8e-14 1.3e-09 6.6e-02 91 AC007362.1
51 2 216800372 218224510 1 1 3.6e-07 1.2e-21 1.5e-19 10 IGFBP2
52 2 229528431 231277567 1 1 4.3e-22 3.0e-92 2.3e-86 6 DNER
53 2 233687080 235170697 1 1 2.4e-09 2.4e-08 2.7e-03 71 USP40
54 2 238531976 239996179 1 2 2.7e-10 4.1e-83 3.4e-93 -12 TRAF3IP1
55 2 241332207 243048760 10 5 5.0e-10 4.3e-14 1.4e-04 75 AC114730.7 BOK FARP2 MTERFD2
56 3 3838266 5232074 1 1 4.6e-09 5.2e-15 1.8e-07 55 ITPR1-AS1
57 3 10617048 12457119 2 2 5.8e-13 4.8e-19 1.9e-07 66 ATG7 VGLL4
58 3 13527134 14942024 1 1 2.6e-07 9.5e-18 6.5e-13 30 LSM3
59 3 24520283 26396178 2 2 2.7e-26 6.4e-67 1.5e-48 28 RARB TOP2B
60 3 40594264 42967174 2 1 2.1e-11 5.7e-11 1.0e+00 100 ULK4
61 3 44079200 45500950 1 1 3.1e-08 4.7e-08 1.2e-01 92 KIAA1143
62 3 48702606 50546340 7 1 9.5e-10 1.3e-09 2.4e-01 96 UBA7
63 3 51860817 53415468 3 1 3.2e-08 4.6e-07 1.6e-01 92 GNL3
64 3 54508115 56217454 2 2 2.9e-12 1.7e-33 2.8e-33 1 RP11-889D3.1 WNT5A
65 3 56564752 58613378 7 1 2.1e-25 5.8e-26 1.0e+00 100 SLMAP
66 3 72238172 74372906 2 2 2.4e-16 1.6e-15 6.2e-13 18 GXYLT2 PDZRN3
67 3 126695780 129317585 7 11 8.1e-46 1.7e-45 1.0e+00 100 ABTB1 ACAD9 EEFSEC RAB7A RPN1 RUVBL1 SEC61A1
68 3 137031237 138451352 1 1 1.8e-10 8.4e-12 3.6e-04 73 CLDN18
69 3 141992282 143476411 2 1 1.7e-07 1.7e-07 3.0e-01 96 U2SURP
70 3 151262987 152878838 1 1 4.1e-07 9.8e-08 7.0e-02 88 MBNL1
71 3 153142317 154733231 2 1 1.5e-13 2.0e-12 1.2e-01 95 ARHGEF26
72 3 155070465 157226796 5 2 4.5e-14 2.1e-13 2.4e-01 98 RP11-305K5.1 SSR3
73 3 182655858 184099956 1 1 1.3e-09 6.9e-10 5.1e-02 90 KLHL24
74 3 194754763 196158773 1 1 2.8e-07 3.3e-06 1.9e-05 16 MUC20
75 4 7060959 8621167 2 1 2.3e-12 3.2e-15 2.9e-06 65 AFAP1
76 4 9370814 10812968 3 1 3.9e-08 7.3e-09 4.0e-02 87 SLC2A9
77 4 53038557 54427925 1 1 6.3e-10 3.0e-10 1.1e-03 73 RASL11B
78 4 55582068 56988744 1 1 1.2e-08 9.6e-07 2.2e-05 25 TMEM165
79 4 57080198 58500584 1 1 4.0e-07 1.1e-07 3.7e-02 85 REST
80 4 76342004 77927345 2 1 1.2e-08 1.1e-07 6.6e-03 74 NUP54
81 4 82859484 84414282 1 1 3.1e-07 9.8e-07 1.0e-05 19 SCD5
82 4 88604547 90916437 5 5 1.0e-45 5.1e-96 5.0e-28 72 FAM13A HERC6 NAP1L5 TIGD2
83 4 105598022 107931444 5 6 1.6e-53 5.5e-55 1.4e-17 70 INTS12 NPNT PPA2 TBCK
84 4 112366943 113899790 3 1 5.5e-09 3.9e-08 6.7e-02 89 AP1AR
85 4 139253139 141220335 5 1 5.8e-15 2.3e-15 2.8e-03 86 RAB33B
86 4 144104906 146788825 7 10 1.1e-99 3.9e-255 4.6e-99 62 GYPA GYPE HHIP-AS1 OTUD4 RP11-361D14.2 RP11-673E1.1 RP11-673E1.3
87 4 152543783 155397517 5 2 7.8e-13 5.9e-16 5.3e-06 68 ARFIP1 SFRP2
88 5 12225 1390349 6 1 2.3e-19 2.2e-21 1.0e+00 100 AC026740.1
89 5 12998006 14640921 1 1 7.7e-08 4.0e-11 1.6e-05 57 DNAH5
90 5 33958959 35523639 1 1 5.0e-11 1.3e-10 2.8e-01 97 RAI14
91 5 42831514 44249820 1 1 4.7e-08 4.1e-11 2.9e-05 60 PAIP1
92 5 49462228 50432178 1 1 1.5e-08 1.2e-08 1.0e+00 100 EMB
93 5 51425511 53104869 5 6 8.5e-16 6.3e-58 2.3e-103 -81 CTD-2366F13.1 CTD-2366F13.2 ITGA1 ITGA2 MOCS2
94 5 53116123 55272596 2 2 2.4e-07 1.5e-08 4.2e-02 87 RP11-506H20.1 SNX18
95 5 71557313 73083183 1 1 4.8e-08 3.7e-06 3.6e-04 40 FCHO2
96 5 75812681 78353059 3 2 9.5e-10 2.4e-12 3.8e-04 74 CTD-2037K23.2 PDE8B
97 5 80873851 82264985 1 1 2.1e-07 5.6e-07 1.4e-06 7 RPS23
98 5 93348659 95856679 6 1 2.7e-42 4.6e-49 6.3e-12 78 SPATA9
99 5 97434545 99024399 4 1 1.1e-16 6.8e-15 9.8e-01 100 CTD-2007H13.3
100 5 111667502 113515807 1 1 5.9e-08 7.4e-08 2.7e-02 83 MCC
101 5 120708748 122492523 2 2 1.2e-15 7.3e-29 2.3e-18 38 LOX SNCAIP
102 5 125506061 128116643 4 2 1.9e-15 3.9e-15 1.0e+00 100 C5orf63 CTC-228N24.3
103 5 130451873 133140038 17 10 6.9e-29 1.0e-37 NaN NaN AC004041.2 C5orf56 MIR3936 PDLIM4 SLC22A4 SLC22A5 UQCRQ ZCCHC10
104 5 147012186 149420698 5 4 1.8e-74 1.7e-147 2.7e-66 56 AFAP1L1 HTR4 SH3TC2 SPINK9
105 5 149787068 151886485 4 3 4.5e-22 4.5e-23 6.8e-03 92 CCDC69 G3BP1 GM2A
106 5 155758384 157879489 7 9 4.4e-106 9.1e-97 1.0e+00 100 ADAM19 HAVCR1 MED7
107 5 172620700 174088123 1 1 1.1e-14 4.5e-21 8.7e-22 -4 CPEB4
108 5 176086479 177626134 2 1 1.1e-07 1.4e-12 8.9e-09 34 RP11-1277A3.3
109 5 177789202 179203479 1 1 8.0e-10 3.3e-12 5.3e-12 2 ZNF354C
110 6 202452 1392108 1 1 3.1e-08 5.0e-09 7.0e-04 66 EXOC2
111 6 6701209 8278455 2 2 1.5e-27 1.7e-49 1.7e-51 -4 DSP RIOK1
112 6 17060849 18686970 1 1 1.2e-07 3.2e-11 4.4e-05 62 KIF13A
113 6 20966438 22913739 1 1 1.5e-08 1.1e-55 1.9e-49 12 CASC15
114 6 33856903 36207973 8 7 2.2e-21 1.0e-18 NaN NaN C6orf106 DEF6 RPL10A ZNF76
115 6 55625041 58206146 5 2 5.2e-09 1.8e-15 1.0e-08 48 KIAA1586 PRIM2
116 6 89941356 91704536 1 1 2.4e-10 5.4e-16 4.5e-07 61 BACH2
117 6 108183628 110710018 7 6 2.1e-16 2.8e-82 2.5e-56 32 ARMC2 FOXO3 RP11-425D10.10 SESN1 SMPD2
118 6 115569351 120041948 8 4 1.1e-10 8.2e-16 2.5e-08 52 DCBLD1 FRK RP11-351A11.1 ZUFSP
119 6 121058929 122457698 1 1 3.3e-10 2.2e-15 6.4e-08 54 GJA1
120 6 125970401 127355237 1 1 1.2e-11 5.1e-12 1.0e+00 100 CENPW
121 6 140469979 143855272 4 6 5.8e-215 5.0e-234 1.0e+00 100 GPR126 HIVEP2 RP3-460G2.2 VTA1
122 7 2032803 3581391 2 1 1.0e-17 2.8e-16 1.6e-02 91 GNA12
123 7 6502367 7988091 1 1 1.5e-17 2.6e-15 9.7e-03 89 C1GALT1
124 7 19674247 21151172 2 1 9.9e-10 2.6e-12 6.0e-04 76 CTA-293F17.1
125 7 73425238 74494207 2 1 2.5e-08 3.3e-13 3.8e-12 9 GTF2IRD2
126 7 89057368 90739777 4 1 5.9e-10 6.4e-10 6.3e-02 91 DPY19L2P4
127 7 98356158 100865847 21 2 2.1e-28 2.0e-25 7.3e-02 97 ATP5J2 CNPY4
128 7 115619298 117135212 1 1 5.5e-12 1.7e-12 1.0e+00 100 MET
129 7 120294932 121729795 1 1 2.2e-08 1.8e-10 2.1e-05 55 FAM3C
130 7 129342404 130839735 2 1 2.6e-08 1.7e-08 3.4e-02 86 CEP41
131 7 134081554 135590031 2 1 4.1e-08 8.7e-18 2.0e-12 33 WDR91
132 7 139088401 140572110 1 1 1.4e-09 4.7e-09 1.5e-02 83 JHDM1D
133 8 8295058 9708433 1 1 7.6e-10 1.2e-14 2.2e-07 55 PPP1R3B
134 8 16188310 18955169 9 9 6.8e-22 3.2e-22 0.0e+00 -5570 ASAH1 MICU3 NAT1 PCM1
135 8 21758119 23240950 5 1 8.2e-09 5.0e-09 1.6e-01 94 CTD-3247F14.2
136 8 29223230 30694153 2 1 5.3e-08 5.9e-08 1.0e+00 100 TMEM66
137 8 56282834 57683880 1 1 3.7e-07 2.0e-07 1.5e-01 92 RPS20
138 8 70854206 72974329 2 1 2.9e-08 1.6e-08 1.0e+00 100 LACTB2
139 8 73280829 74727081 1 1 3.9e-10 5.3e-09 7.6e-01 100 SBSPON
140 8 100277018 101937374 2 1 1.3e-07 5.5e-07 3.0e-01 96 SPAG1
141 8 102002608 103832256 2 1 8.8e-11 4.8e-16 1.6e-12 24 KB-1107E3.1
142 8 108515373 110190556 3 1 3.0e-16 1.6e-15 1.7e-03 84 EIF3E
143 8 119737284 121763223 3 1 2.5e-10 1.1e-10 2.4e-06 47 DEPTOR
144 8 125745994 127150370 1 1 1.3e-07 3.6e-08 7.8e-08 5 TRIB1
145 8 130160834 132106838 2 2 5.3e-08 5.7e-09 3.8e-02 87 ASAP1 FAM49B
146 8 140969818 142706843 1 1 9.0e-08 1.1e-07 4.6e-03 72 PTK2
147 9 5521655 6957024 1 1 3.6e-07 1.1e-09 6.8e-06 46 IL33
148 9 14857740 16758776 1 1 1.5e-11 2.8e-12 4.8e-02 92 CCDC171
149 9 33130640 35043291 2 2 1.6e-07 5.4e-08 4.2e-01 98 NUDT2 UBE2R2
150 9 35641859 37183628 1 1 2.2e-07 1.8e-07 1.0e+00 100 RNF38
151 9 37222681 38765310 1 1 2.1e-09 3.1e-11 3.4e-04 71 SHB
152 9 88200133 89668506 2 1 8.4e-18 2.4e-17 7.0e-02 95 ISCA1
153 9 95502571 96898436 1 1 2.5e-07 1.9e-10 1.4e-04 64 RP11-165J3.6
154 9 97520168 98975128 2 4 1.7e-37 8.5e-46 1.0e+00 100 PTCH1 RP11-435O5.5
155 9 99707397 102521881 4 3 5.8e-14 2.9e-14 2.2e-07 54 C9orf156 COL15A1 XPA
156 9 131169528 132569553 1 1 1.2e-07 9.7e-07 2.8e-01 95 CRAT
157 10 3123433 4526111 1 1 6.2e-09 2.3e-10 1.8e-03 76 KLF6
158 10 11087863 13569805 5 5 1.6e-74 5.1e-97 2.6e-42 57 CAMK1D CDC123 NUDT5 SEC61A2
159 10 21123825 22724472 1 1 1.3e-10 5.7e-15 1.0e-13 9 MLLT10
160 10 30411253 32016090 1 1 1.5e-13 4.1e-14 2.9e-02 92 ZNF438
161 10 32035353 33875979 2 1 7.7e-12 4.4e-11 5.0e-03 82 CCDC7
162 10 51801913 53080509 1 1 1.2e-07 3.1e-08 1.4e-02 80 SGMS1
163 10 63856856 66034105 5 1 9.4e-20 6.5e-16 1.1e-04 77 NRBF2
164 10 74173864 79018276 18 7 2.7e-16 3.2e-21 NaN NaN C10orf11 CHCHD1 FAM149B1 MRPS16 NUDT13
165 10 80589774 82984432 19 9 5.6e-24 2.4e-22 NaN NaN FAM213A MBL1P RP11-137H2.6 RP11-506M13.3 SFTPD TSPAN14
166 10 95606207 97070115 1 1 1.4e-08 8.3e-09 3.1e-02 86 HELLS
167 10 103527782 106314564 3 3 1.5e-13 4.6e-17 7.2e-08 59 ACTR1A RP11-541N10.3 TMEM180
168 10 110937872 112588355 2 1 7.3e-10 2.7e-10 1.0e+00 100 ADD3
169 10 120269685 121907055 1 1 3.7e-08 2.6e-08 6.8e-08 6 GRK5
170 10 123438113 124889817 1 1 1.3e-09 1.8e-14 1.4e-08 45 PLEKHA1
171 11 198510 1479601 3 2 1.4e-10 2.0e-08 9.0e-01 100 AP006621.5 IFITM3
172 11 3177939 4922016 2 1 2.3e-10 2.4e-10 1.0e+00 100 STIM1
173 11 8001014 11227175 11 6 1.4e-12 3.5e-15 2.9e-08 50 ADM AMPD3 DENND5A SBF2 TMEM41B TMEM9B
174 11 29646947 31048683 1 1 3.7e-08 6.9e-10 2.9e-03 77 ARL14EP
175 11 34189564 35732073 2 8 1.9e-15 5.8e-13 NaN NaN APIP PDHX
176 11 56666189 58284951 6 1 6.9e-14 9.0e-12 6.5e-01 100 SERPING1
177 11 61479322 63110149 2 2 2.7e-09 4.2e-09 1.4e-02 83 GANAB SCGB1A1
178 11 64615450 66011280 1 1 6.3e-08 2.7e-12 4.8e-06 57 LTBP3
179 11 69606128 70966113 1 1 2.6e-10 5.4e-11 4.7e-14 -32 CTTN
180 11 71339667 74335121 16 14 7.5e-33 4.5e-29 NaN NaN ATG16L2 CLPB FAM168A PDE2A PLEKHB1 RP11-707G14.1 RP11-800A3.7 RP11-809N8.4 STARD10
181 11 77027574 78979645 6 1 1.5e-15 3.6e-16 2.4e-02 92 GAB2
182 11 85262816 86688920 1 1 6.2e-14 5.1e-24 1.8e-12 51 EED
183 11 99859184 101559718 2 2 2.7e-14 1.4e-13 6.5e-03 86 ARHGAP42 TMEM133
184 11 116384511 117800682 1 1 8.8e-08 2.0e-06 2.9e-01 95 PCSK7
185 11 120623637 122199441 1 1 6.9e-10 9.9e-14 2.4e-07 52 SORL1
186 11 124617939 127007433 6 3 1.4e-09 3.1e-17 2.6e-09 50 CDON RP11-680F20.12 ST3GAL4
187 11 130542882 132906064 1 1 1.9e-11 2.7e-27 1.8e-17 38 NTM
188 12 191619 2299048 2 2 2.0e-17 2.7e-16 5.1e-05 76 CCDC77 ERC1
189 12 14575459 16190627 1 1 3.3e-16 2.8e-19 7.8e-05 81 RERG
190 12 27172878 28607631 1 1 2.7e-10 3.6e-11 8.1e-03 84 MRPS35
191 12 51650192 53088525 1 1 1.7e-08 9.0e-20 6.0e-13 37 ACVR1B
192 12 53136542 55276396 4 2 9.2e-11 3.3e-21 2.1e-13 40 FLJ12825 PCBP2
193 12 55601472 58303535 10 2 3.0e-30 8.9e-30 1.0e+00 100 LRP1 SUOX
194 12 89116708 90799212 2 1 8.6e-09 3.9e-09 8.9e-03 80 ATP2B1
195 12 94772262 97056904 6 6 5.7e-43 1.0e-60 7.9e-04 96 AMDHD1 FGD6 RP11-536G4.2 USP44
196 12 101441467 103101412 2 2 1.2e-08 5.3e-06 6.9e-01 99 DRAM1 GNPTAB
197 12 114408276 115813607 1 1 3.3e-08 3.4e-09 3.3e-09 0 TBX3
198 12 123387922 125118479 4 1 2.5e-10 7.3e-10 2.7e-01 97 TCTN2
199 13 28011686 29410882 1 1 2.8e-07 2.3e-08 8.5e-07 22 PAN3-AS1
200 13 39533590 41928314 2 2 7.7e-09 5.1e-11 4.8e-05 62 COG6 FOXO1
201 13 47958937 49351645 1 2 4.0e-08 6.8e-07 5.8e-01 99 MED4-AS1
202 13 49583846 51061044 1 1 1.6e-09 1.6e-15 1.6e-07 57 KPNA3
203 14 22600863 24464590 8 5 6.3e-18 7.7e-15 1.2e-05 68 HAUS4 MRPL52 PPP1R3E RBM23
204 14 51775331 53232305 1 1 4.6e-09 4.9e-11 7.9e-04 74 NID2
205 14 53731553 55118795 1 1 1.4e-36 1.9e-30 7.5e-04 91 BMP4
206 14 73488591 77414761 9 4 1.1e-12 4.7e-16 5.8e-10 42 ELMSAN1 GPATCH2L LIN52 RPS6KL1
207 14 99421061 100845457 1 1 2.6e-09 8.0e-11 3.7e-03 80 HHIPL1
208 15 39530508 43299687 23 11 1.5e-36 6.8e-33 NaN NaN BMF EHD4 EIF2AK4 MAPKBP1 MGA NDUFAF1 RP11-23P13.4 RPAP1
209 15 48584083 52392509 10 8 1.0e-17 1.4e-34 NaN NaN COPS2 FAM227B GLDN RP11-295H24.3 SPPL2A
210 15 62636766 66277821 9 5 2.6e-15 3.0e-28 2.7e-18 37 FAM96A PARP16 PIF1 TPM1 USP3
211 15 66662107 68492262 2 2 1.8e-11 2.3e-14 8.2e-05 73 IQCH SMAD3
212 15 70426659 73087366 5 5 1.1e-229 9.2e-206 6.4e-56 74 CTD-2524L6.3 LARP6 THSD4
213 15 73524629 74915888 1 1 1.0e-10 3.3e-12 3.5e-10 19 LOXL1-AS1
214 15 75253414 79611011 17 9 3.7e-35 4.7e-32 NaN NaN CHRNA5 PEAK1 PSTPIP1 RP11-797A18.4 SNX33 UBE2Q2
215 15 82053795 86489699 22 9 2.6e-29 1.5e-47 NaN NaN AC103965.1 GOLGA6L4 GOLGA6L5 RP11-182J1.16 RP11-382A20.2 SCAND2P UBE2Q2P1 ZSCAN2
216 15 98944630 100972747 4 5 3.2e-16 1.2e-20 NaN NaN LYSMD4 RP11-6O2.4 SYNM
217 16 3608256 5338275 3 2 1.3e-14 3.3e-14 1.0e+00 100 LOC342346 RP11-95P2.1
218 16 29214126 31695263 14 2 4.8e-13 2.2e-11 7.9e-01 100 C16orf93 TBX6
219 16 57311211 59241430 7 1 8.1e-56 7.0e-58 4.8e-08 88 MMP15
220 16 65813302 69084178 42 9 1.0e-29 1.2e-27 NaN NaN ATP6V0D1 CMTM2 CTCF FBXL8 FHOD1 HSF4 LRRC29 RANBP10
221 16 72122463 73789190 1 1 1.2e-07 2.7e-07 6.7e-01 99 ZFHX3
222 16 74270536 76350805 7 3 1.2e-76 3.5e-77 1.0e+00 100 BCAR1 TMEM170A
223 16 85869881 87469883 2 2 5.6e-08 2.1e-15 4.7e-14 10 CTD-2015G9.2 RP11-463O9.1
224 17 3011213 5213391 9 11 5.4e-23 5.1e-27 NaN NaN ANKFY1 ATP2A3 CTD-3195I5.1 CYB5D2 RP11-810M2.2 UBE2G1 ZZEF1
225 17 5664752 8515636 4 3 2.6e-08 6.8e-07 1.0e+00 100 CHD3 KIAA0753 LSMD1
226 17 17017584 18923818 13 3 3.5e-14 1.9e-12 2.5e-01 97 ALKBH5 CCDC144B TOM1L2
227 17 26706946 31275580 22 3 1.5e-52 4.6e-53 1.0e+00 100 CPD LRRC37B SSH2
228 17 36211659 39048774 14 11 2.2e-37 3.1e-31 1.0e+00 100 CWC25 MSL1 ORMDL3 PCGF2 PIP4K2B THRA
229 17 43000481 43913030 1 1 3.6e-07 1.6e-06 9.9e-01 100 CRHR1
230 17 45337417 49307326 14 11 6.2e-15 2.8e-16 0.0e+00 -218500 GNGT2 HOXB2 HOXB3 HOXB-AS1 MYCBPAP NFE2L1 RP11-6N17.6 SNX11 SPOP
231 17 60013554 61464730 1 1 2.8e-19 2.9e-18 2.3e-04 82 MRC2
232 17 61765524 63531331 5 2 4.0e-18 2.4e-17 1.3e-04 80 DDX5 SMURF2
233 17 65123352 66885526 7 1 1.4e-17 9.8e-16 6.1e-01 100 LINC00674
234 17 69417947 70810416 1 1 3.1e-07 8.0e-14 3.6e-08 46 SOX9
235 17 72829885 74267010 1 1 1.0e-11 1.1e-09 5.7e-01 99 LLGL2
236 17 76320835 77734689 1 1 3.0e-07 3.1e-08 4.7e-07 17 C1QTNF1
237 17 78939414 80680449 2 2 8.7e-10 2.6e-08 4.4e-01 98 CCDC137 STRA13
238 18 8010444 11250447 4 6 5.0e-18 1.1e-29 6.8e-43 -47 KIAA0802 NAPG RP11-21J18.1 SOGA2
239 18 19692435 21303692 1 1 2.4e-08 2.1e-19 7.2e-15 25 RBBP8
240 19 1086043 2560423 3 1 4.9e-09 8.7e-11 5.0e-03 81 KLF16
241 19 7211841 9200017 2 2 1.2e-07 1.1e-10 3.0e-05 58 EVI5L MARCH2
242 19 13445144 14854034 1 1 2.6e-07 1.0e-11 1.2e-09 20 IL27RA
243 19 17672385 19081701 1 1 9.6e-08 2.1e-07 1.8e-02 79 KIAA1683
244 19 31077263 32530559 1 1 5.3e-18 6.2e-36 3.7e-22 40 TSHZ3
245 19 36181046 38976177 8 5 2.8e-09 1.7e-09 NaN NaN AC092295.7 CTD-2554C21.1 ZNF260
246 19 40038291 42504505 9 3 1.5e-15 6.5e-13 6.0e-02 93 HNRNPUL1 ITPKC SHKBP1
247 19 44843754 50108983 14 11 1.7e-37 9.6e-36 1.0e+00 100 AC074212.6 CCDC9 DMPK DMWD FOSB FUT2 PNMAL1 QPCTL SFRS16 SYMPK
248 19 51598669 53017693 1 1 5.0e-15 5.0e-15 1.0e+00 100 FPR3
249 20 2961408 4359816 1 1 2.4e-09 3.7e-12 2.5e-04 72 ADAM33
250 20 18506005 20398583 1 1 1.6e-10 6.1e-12 1.1e-02 86 SLC24A3
251 20 24532613 26307797 3 1 6.2e-09 9.4e-09 1.7e-01 94 CTD-2514C3.1
252 20 30060562 35916342 23 10 4.1e-17 1.4e-14 1.2e-01 96 C20orf112 C20orf203 ERGIC3 GSS ITCH MAP1LC3A RP5-1085F17.3 RSL24D1P6 TGIF2 TSPY26P
253 20 43293270 44801026 3 2 2.8e-12 3.1e-11 1.0e+00 100 DBNDD2 WFDC2
254 20 47554392 49028687 1 1 2.0e-10 1.6e-10 2.2e-04 67 B4GALT5
255 20 60064969 61679007 3 2 1.0e-10 3.3e-15 5.8e-09 45 CABLES2 MTG2
256 21 18271223 19680363 1 1 3.8e-10 2.5e-10 1.7e-07 32 BTG3
257 21 27565116 29033093 2 1 3.5e-12 2.3e-10 9.3e-01 100 AP001601.2
258 21 34589270 36786042 4 4 1.6e-21 7.6e-37 1.9e-34 7 CLIC6 LINC00310 LINC00649 MRPS6
259 21 39849553 41512399 5 1 4.5e-09 3.6e-09 3.2e-03 75 BRWD1-IT2
260 22 17581838 19203078 1 1 1.2e-26 3.7e-27 9.2e-04 91 MICAL3
261 22 19262852 20330744 2 2 1.6e-16 2.7e-15 3.2e-03 86 ARVCF ZDHHC8
262 22 20732809 21465050 2 3 6.9e-10 7.3e-28 1.3e-10 65 MED15 ZNF74
263 22 29015590 31171274 10 9 1.4e-28 5.5e-29 NaN NaN AP1B1 ASCC2 CTA-85E5.10 MTMR3 NIPSNAP1 UQCR10
264 22 40472399 43740418 9 4 1.6e-13 1.5e-12 1.2e-05 62 CYB5R3 EP300 RRP7A Z83851.1

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Alzheimer’s Disease (in mother) 1.13 1 1 3.0 0.00 1.0e+00 SFRS16
Alzheimer’s Disease (including proxy) 1.15 3 1 3.0 0.00 1.0e+00 EED SFRS16 SPPL2A
Crohns Disease (2017) 1.59 15 12 36.4 -0.77 4.4e-04 AC010883.5 ADCY3 C5orf56 FUT2 ITPKC MIR3936 ORMDL3 PDLIM4 SH3D21 SLC22A4 SLC22A5 SMAD3 STARD10 TSPAN14 UQCRQ
Irritable Bowel Disease (IBD) 1.53 18 12 36.4 -0.64 2.9e-03 AC010883.5 ADCY3 AHSA2 BACH2 C5orf56 ITPKC MIR3936 ORMDL3 PDLIM4 RP11-1277A3.3 SLC22A4 SLC22A5 SMAD3 STARD10 TSPAN14 UBA7 UQCR10 UQCRQ
Ulcerative Colitis (UC) 1.25 6 4 12.1 -0.46 3.6e-01 AC026740.1 AHSA2 ORMDL3 RP3-395M20.9 UBA7 UQCR10
Major Depression (MDD) 1.28 2 1 3.0 0.00 1.0e+00 NEGR1 PTCH1
Reaction Time 1.10 3 1 3.0 -0.98 1.6e-02 DNAJB4 FOXO3 GIPC2
Verbal and Numeric Reasoning (VNR) 1.10 10 4 12.1 0.14 7.0e-01 ALKBH5 BTG3 CRHR1 FOXO3 GNL3 NEGR1 PEF1 PPA2 SUOX UBA7
Breast Cancer 1.10 13 7 21.2 -0.49 7.2e-02 ADCY3 AP006621.5 C5orf56 CPEB4 CRHR1 IGFBP2 MIR3936 MLLT10 PCM1 RPS23 SLC22A5 UQCRQ ZCCHC10
Ovarian Cancer 1.21 4 3 9.1 -0.53 3.5e-01 CRHR1 DNALI1 HOXB2 HOXB-AS1
Prostate Cancer 1.45 6 3 9.1 0.86 1.2e-03 EEFSEC NUCKS1 RIF1 RPN1 RUVBL1 SEC61A1
Age at First Birth 1.02 1 1 3.0 0.00 1.0e+00 UBA7
Bipolar Disorder 1.56 1 0 0.0 0.00 1.0e+00 GNL3
Body Mass Index (BMI) (2010) 1.21 2 2 6.1 0.00 1.0e+00 ADCY3 NEGR1
Coronary Artery Disease (CAD) 1.32 1 1 3.0 0.00 1.0e+00 CELSR2
Crohns Disease (2012) 1.39 9 9 27.3 0.71 2.1e-02 C5orf56 FUT2 MIR3936 ORMDL3 PDLIM4 SLC22A4 SLC22A5 SMAD3 UQCRQ
Fasting Glucose 1.31 2 0 0.0 0.00 1.0e+00 QPCTL STARD10
HDL Cholesterol 1.43 8 5 15.2 0.21 5.6e-01 ATP6V0D1 C6orf106 CTCF FHOD1 MAPKBP1 ORMDL3 PABPC4 RPAP1
LDL Cholesterol 1.61 6 3 9.1 0.15 7.8e-01 C6orf106 CELSR2 EVI5 FOSB FUT2 RP11-680F20.12
Lupus 1.12 1 1 3.0 0.00 1.0e+00 APIP
Neuroticism 1.16 3 3 9.1 0.00 1.0e+00 ADM CRHR1 SBF2
Primary Biliary Cirrhosis 1.18 1 1 3.0 0.00 1.0e+00 ORMDL3
Rheumatoid Arthritis 1.28 1 0 0.0 0.00 1.0e+00 YRDC
Schizophrenia 1.04 6 5 15.2 -0.91 4.9e-03 AC103965.1 ACTR1A GNL3 GOLGA6L5 RP11-182J1.16 UBE2Q2P1
Triglycerides 1.08 3 2 6.1 0.00 1.0e+00 NRBF2 PABPC4 PCSK7
Type 2 Diabetes (T2D) 1.37 1 0 0.0 0.00 1.0e+00 STARD10
Ulcerative Colitis 1.31 3 2 6.1 0.00 1.0e+00 BCAR1 ORMDL3 RP3-395M20.9
Blood Eosinophil Count 2.11 72 55 166.7 -0.28 1.1e-02 AC010883.5 AC103965.1 AC114730.7 ADD3 AHSA2 ATP6V0D1 BACH2 C16orf93 C20orf112 C5orf56 CCDC9 CHD3 COG6 CPEB4 CRHR1 CTA-293F17.1 CTD-2007H13.3 DMPK DMWD EEFSEC EHD4 FBXL8 FCHO2 FHOD1 FOXO1 GNA12 GNGT2 GNL3 HAUS4 HTR4 IL18R1 IL33 IQCH ITPKC LINC00674 LOC342346 LRP1 MIR3936 MSL1 NDUFAF1 PCBP2 PDLIM4 PSTPIP1 QPCTL RAB7A RBBP8 RBM23 REST RP11-1277A3.3 RP11-182J1.16 RP11-425D10.10 RP11-680F20.12 RP3-395M20.9 RPL10A RPN1 RUVBL1 SCD5 SESN1 SLC22A4 SLC22A5 SMAD3 SMPD2 SUOX SYMPK TBX6 THRA TOM1L2 TSPY26P UQCRQ YRDC ZSCAN2 ZUFSP
Blood Platelet Count 1.30 109 83 251.5 -0.31 3.1e-04 AC010883.5 AC074212.6 AC092295.7 AC103965.1 ADD3 ANKFY1 AP006621.5 ASCC2 BCAR1 BOK BRWD1-IT2 C10orf11 C16orf93 C1orf43 C20orf203 C5orf56 C6orf106 C9orf156 CAPZB CHD3 CNTN2 CRHR1 CTD-2037K23.2 CTD-3247F14.2 CYB5R3 DEPTOR DMWD DNAJB4 DRAM2 EEFSEC EHD4 EVI5 FCGR2B FCHO2 FGD6 FLJ12825 FOXO1 FUT2 GIPC2 GNA12 GNL3 GSS GYPE HELLS HHIP-AS1 HOXB2 HSPD1 IMMT ITGA2 JHDM1D KIF1B LOC342346 LSMD1 LTBP3 MARCH7 MIR3936 MUTYH NEXN NRBF2 OTUD4 OXER1 PABPC4 PARP16 PCSK7 PDE8B PDLIM4 PIF1 QPCTL RAI14 RANBP10 RAPH1 RARB REST RP11-137H2.6 RP11-165J3.6 RP11-182J1.16 RP11-361D14.2 RP11-425D10.10 RP11-673E1.1 RP11-797A18.4 RP11-800A3.7 RP1-18D14.7 RP11-95P2.1 RPS6KL1 RUVBL1 SCGB1A1 SEC61A1 SERPING1 SERTAD2 SH3D21 SLC22A4 SLC22A5 SMPD2 SNX33 SSH2 SYMPK TIGD2 TMEM170A TMEM180 TMEM185B TOP2B TPM1 TRIT1 UBE2R2 UQCRQ Z83851.1 ZNF260 ZSCAN2 ZZEF1
Blood Red Count 1.11 84 66 200.0 0.07 4.9e-01 ADM ALKBH5 ATP6V0D1 ATPAF1 BACH2 C16orf93 C20orf203 C9orf156 CENPW CHRNA5 CNPY4 CNTN2 CPD CPEB4 CRHR1 CTCF CTD-2514C3.1 CTD-2524L6.3 DCBLD1 DEPTOR EHD4 EIF2AK4 EPHA2 FCGR2B FOXO1 GAB2 GJA1 GNL3 GPATCH2L GSS GYPE HELLS HOXB2 HOXB3 HOXB-AS1 HSF4 LIN52 LINC00649 LSMD1 MAPKBP1 MARCH7 MFAP2 MRC2 MST1L MST1P2 MUC20 MUTYH NBPF1 ORMDL3 PABPC4 PRIM2 PSTPIP1 RAI14 RANBP10 RP11-1277A3.3 RP11-182J1.16 RP11-23P13.4 RP11-425D10.10 RP11-435O5.5 RP11-673E1.1 RP11-797A18.4 RP1-18D14.7 RPAP1 RSL24D1P6 SBF2 SCAMP3 SERPING1 SERTAD2 SESN1 SHKBP1 SMPD2 SNX33 SSH2 STRA13 SUOX SYMPK TBX6 TMEM165 TMEM9B TRMT61B UBE2Q2 UBE2Q2P1 ULK4 WDR91
Blood White Count 1.92 69 53 160.6 -0.23 4.1e-02 AC007319.1 ACTR1A ADAM33 AHSA2 ALKBH5 ARHGAP42 ASCC2 BACH2 C16orf93 C5orf56 CALCRL CCDC9 CENPW CRHR1 CTA-85E5.10 DEF6 EHD4 EVI5 FAM213A FCGR2B GLDN GM2A GNA12 HELLS HSPD1 HTR4 IFITM3 ITCH ITGA2 ITPKC KB-1107E3.1 KLF6 LOC342346 MARCH7 MIR3936 MSL1 MTMR3 NFE2L1 NRBF2 ORMDL3 PDLIM4 PEAK1 PSTPIP1 PTCH1 RAB7A RAI14 REST RIOK1 RP11-23P13.4 RP11-435O5.5 RP11-6N17.6 RP11-797A18.4 RPN1 SCD5 SLC22A4 SLC22A5 SMPD2 SPINK9 SPPL2A SSH2 TBX6 THRA TIGD2 TOM1L2 TSPAN14 UBA7 UQCR10 UQCRQ ZNF76
Heel T-Score 1.75 93 68 206.1 0.14 1.8e-01 AC010883.5 AC103965.1 ANKFY1 AP1B1 ARL14EP ATP6V0D1 BMP4 C16orf93 CALCRL CAPZB CCDC77 CHD3 CMTM2 CPD CPEB4 CRHR1 CTA-85E5.10 CTC-228N24.3 CYBRD1 DDX5 DNAJC11 EIF3E EP300 EVI5 FAM213A FAM3C FCHO2 GAB2 GJA1 GLDN GNA12 GOLGA6L5 GPR126 GRK5 GSS HHIP-AS1 HOXD-AS1 HSF4 IQCH ITCH ITPR1-AS1 KPNA3 LACTB2 LSMD1 LTBP3 MAP1LC3A MARCH2 MBL1P MRC2 MTA3 MTMR3 NEGR1 NFE2L1 OTUD4 PCGF2 PDE2A PEAK1 PIP4K2B RANBP10 REST RP11-1277A3.3 RP11-137H2.6 RP11-165J3.6 RP11-361D14.2 RP11-435O5.5 RP11-6N17.6 RP11-810M2.2 RP11-95P2.1 RPL10A RPN1 RPS20 RRP15 SERPING1 SERTAD2 SFTPD SPPL2A SSH2 SSR3 STRA13 THAP3 THSD4 TMEM9B TRAF3IP1 TRMT61B TSPAN14 UBE2Q2P1 UQCR10 USP3 VGLL4 ZCCHC10 ZNF438 ZNF76 ZZEF1
BMI 1.35 64 43 130.3 0.39 9.6e-04 ACTR1A ADCY3 ANKFY1 ARHGEF26 ARL14EP C16orf93 C6orf106 CCDC171 CEP41 CPD CPEB4 CTD-2524L6.3 DNAJB4 DNAJC11 EEFSEC EP300 EVI5 FOSB FOXO3 GAB2 GIPC2 GNL3 GTF2IRD2 HOXB-AS1 HSPD1 HTR4 IQCH ITCH KB-1107E3.1 KIAA1683 KLF16 KLHL24 LINC00674 LOXL1-AS1 LRP1 MFAP2 MLLT10 MST1L MST1P2 MUTYH NDUFAF1 NEGR1 NEXN NFE2L1 NRBF2 OTUD4 PABPC4 PEF1 PSTPIP1 RAB7A RP11-797A18.4 RP1-18D14.7 RP3-395M20.9 RPL10A RPN1 SHISA4 SNX11 SSH2 SUOX TBX6 TRMT61B UBA7 Z83851.1 ZZEF1
Height 2.33 191 167 506.1 -0.12 8.6e-02 AC010883.5 AC074212.6 AC103965.1 ACAD9 ADAM17 ADAM33 ADCY3 ADM AFAP1 ALKBH5 ARHGEF26 ARL14EP ASAH1 ASCC2 ATP6V0D1 BCAR1 BMF BOK BTBD8 C10orf11 C1orf43 C1QTNF1 C5orf56 C6orf106 C9orf156 CABLES2 CCDC144B CCDC9 CELSR2 CENPW CHD3 COG6 COL15A1 CRHR1 CRIM1 CTA-293F17.1 CTA-85E5.10 CTCF CTD-2524L6.3 CTD-2554C21.1 CWC25 CYB5R3 CYBRD1 DDX5 DEF6 DEPTOR DMWD DNAJB4 DRAM1 EED EFEMP1 EIF2AK4 ERC1 ERGIC3 EVI5 EXOC2 FAM171B FARP2 FOXO3 FRK FUT2 GAB2 GIPC2 GLDN GNA12 GNGT2 GNL3 GNPTAB GOLGA6L4 GOLGA6L5 GPR126 GRK5 GSS GTF2IRD2 GYPA GYPE HHIP-AS1 HIVEP2 HOXB2 HOXB-AS1 HSPD1 INTS12 ISCA1 ITCH ITPKC KIAA0753 KIF1B KLHL24 KPNA3 LIN52 LINC00674 LLGL2 LOX LOXL1-AS1 LRP1 LRRC29 LRRC37B LSM3 LYSMD4 MAP1LC3A MARCH2 MBL1P MET MFAP2 MIR3936 MRC2 MRPS6 MSL1 MST1L MST1P2 MTG2 MTMR11 MUTYH NBPF1 NDUFAF1 NEXN NFE2L1 NUCKS1 NUDT2 OTUD4 PABPC4 PADI2 PDE2A PDHX PDLIM4 PEAK1 PEF1 PIP4K2B PLEKHA1 PPA2 PSTPIP1 PTCH1 QPCTL RANBP10 RBBP8 REST RP11-108M9.5 RP11-1277A3.3 RP11-165J3.6 RP11-182J1.16 RP11-361D14.2 RP11-382A20.2 RP11-425D10.10 RP11-435O5.5 RP11-506H20.1 RP11-506M13.3 RP11-673E1.1 RP11-673E1.3 RP11-6N17.6 RP11-797A18.4 RP11-810M2.2 RP11-95P2.1 RPL10A RPS20 RPS6KL1 RRP15 SBF2 SCAND2P SCD5 SEC61A2 SESN1 SGMS1 SH3D21 SHKBP1 SLC22A4 SLC22A5 SLC2A9 SMPD2 SMURF2 SNCAIP SNX11 SOX9 SPPL2A SSH2 ST3GAL4 STRA13 TBX6 TCTN2 TMEM165 TMEM170A TMEM180 TMEM185B TRAF3IP1 TRIB1 UBE2Q2 UBE2Q2P1 UBE2R2 UQCRQ ZNF354C ZNF76 ZSCAN2
Waist Hip Ratio (WHR) 1.66 60 41 124.2 0.24 5.1e-02 AC007319.1 AC010883.5 AC074212.6 AC103965.1 ADM ALKBH5 AMPD3 ANKFY1 AP006621.5 ARHGEF26 ATP6V0D1 C10orf11 CALCRL CCDC144B CENPW CEP41 CFH COL15A1 CPEB4 CRHR1 CTC-228N24.3 CTCF DMWD EHD4 ERGIC3 FAM13A FAM171B FLJ12825 FOXO3 FUT2 GANAB GLDN GNL3 GOLGA6L5 HHIP-AS1 IQCH KIAA1683 LYSMD4 MAPKBP1 MFAP2 MST1P2 NID2 OTUD4 PIP4K2B RANBP10 RP11-182J1.16 RP11-23P13.4 RP11-361D14.2 RP11-95P2.1 RPAP1 SBF2 SCGB1A1 TCTN2 TOM1L2 U2SURP UBE2G1 UBE2Q2P1 ZCCHC10 ZNF354C ZZEF1
Systolic Blood Pressure 1.59 75 46 139.4 -0.33 2.8e-03 ACTR1A ADCY3 ADM AFAP1 ARHGAP42 ARHGEF26 ATP2B1 BCAR1 BMP4 C1GALT1 CAMK1D CCDC77 CDC123 CPEB4 CRHR1 CTA-85E5.10 CTC-228N24.3 CTD-2015G9.2 CTD-2514C3.1 DCBLD1 DDX5 DMPK DMWD DNAJC11 EHD4 EIF2AK4 ELMSAN1 EPHA2 FAM213A FOXO3 FUT2 GIPC2 GNGT2 GNL3 HAUS4 HELLS HHIPL1 HOXD-AS1 HTR4 KB-1107E3.1 KIAA0753 LOC342346 MAPKBP1 MET MRC2 NDUFAF1 NEXN NRBF2 NUDT13 NUDT5 OXER1 QPCTL RBM23 RP11-137H2.6 RP11-23P13.4 RP11-6N17.6 RP11-800A3.7 RPL10A RPS6KL1 SBF2 SCD5 SEC61A1 SERPING1 SH3TC2 SLC24A3 SMAD3 SNX11 SPINK9 TMEM133 TMEM170A TSHZ3 TSPAN14 ULK4 VGLL4 ZCCHC10
Smoking Status 1.22 12 3 9.1 -0.31 3.2e-01 ACTR1A GNGT2 IQCH MET MLTK MRPS6 RARB SUOX TOP2B UBA7 Z83851.1 ZFHX3
Allergy or Eczema 1.64 28 15 45.5 -0.41 1.6e-02 AC010883.5 AC114730.7 AMPD3 BACH2 BCAR1 C1orf43 C6orf106 CALCRL FOXO1 GRK5 IL18R1 IQCH LRP1 MSL1 NDUFAF1 NEGR1 ORMDL3 PDLIM4 SESN1 SLC22A4 SLC22A5 SMAD3 SPOP SUOX THRA TMEM170A TOM1L2 UQCRQ
Cardiovascular Disease 1.46 35 17 51.5 -0.14 4.2e-01 AC007319.1 ANKFY1 ARHGAP42 ARL14EP ATP2B1 BCAR1 C1GALT1 CELSR2 CEP41 CPEB4 DNAJC11 EEFSEC EHD4 FLJ12825 FUT2 GNGT2 HTR4 KB-1107E3.1 KLF16 MET NDUFAF1 NEGR1 NRBF2 PABPC4 RP11-810M2.2 SCD5 SHISA4 SSH2 SUOX TMEM133 TMEM170A TSPY26P VGLL4 ZCCHC10 ZZEF1
Hypothyroidism (self reported) 1.26 11 7 21.2 0.28 4.1e-01 ASCC2 ATP6V0D1 BACH2 C9orf156 CTCF KIAA1683 PLEKHA1 RANBP10 SESN1 SUOX UQCR10
Respiratory disease 2.85 34 23 69.7 -0.75 8.1e-09 ABTB1 AC114730.7 ADAM19 BACH2 C16orf93 C1orf43 C5orf56 DDX5 DEF6 DMWD EEFSEC FOXO1 GNGT2 IL18R1 IL33 IQCH LRP1 LTBP3 MIR3936 MSL1 ORMDL3 PABPC4 PDLIM4 REST RP11-425D10.10 RUVBL1 SLC22A4 SLC22A5 SMAD3 SUOX THRA TSPAN14 UQCRQ ZNF76
Type 2 Diabetes (T2D) 1.58 11 7 21.2 -0.56 4.7e-02 AC010883.5 ANKFY1 C1GALT1 CAMK1D CENPW CLPB MAPKBP1 NUDT5 PABPC4 STARD10 ZZEF1
Lung FVC 2.02 98 67 203.0 -0.26 6.6e-03 AFAP1L1 ANKFY1 ASCC2 ATP6V0D1 BMF BMP4 BOK C10orf11 C1GALT1 C5orf56 C6orf106 CAMK1D CCDC171 CCDC7 CDC123 CENPW CFH CHRNA5 CNTN2 CPD CRHR1 CTA-85E5.10 CTC-228N24.3 CTD-2514C3.1 CTD-3247F14.2 CYB5D2 CYB5R3 DNER DSP EFEMP1 EIF2AK4 EPHA2 EPHX4 ERC1 ERGIC3 FHOD1 FOXO3 GM2A GNGT2 GPD2 GSS HOXB2 HOXB-AS1 HTR4 INTS12 IQCH ITCH KIAA0802 LIN52 LLGL2 LONRF2 LOXL1-AS1 LRRC29 MAP1LC3A MFAP2 MICAL3 MIR3936 MRPS6 MST1L MST1P2 NFE2L1 NRBF2 NUCKS1 NUDT5 PAIP1 PCSK7 PDE2A PDLIM4 PTCH1 RBBP8 REST RP11-361D14.2 RP11-378J18.8 RP11-382A20.2 RP11-435O5.5 RP11-541N10.3 RPL10A RPS20 RRP15 SHKBP1 SLC22A4 SLC22A5 SLMAP SMPD2 SMURF2 SNCAIP SOGA2 STARD10 STRA13 SUOX TBX3 THSD4 TIGD2 TRAF3IP1 UBA7 ZCCHC10 ZFHX3 ZZEF1
Neuroticism 1.12 10 3 9.1 -0.07 8.2e-01 ADM BTG3 CENPW CRHR1 GAB2 IQCH PTCH1 RPS6KL1 SBF2 SERPING1
Chronotype (morning person) 1.17 7 1 3.0 -0.40 3.7e-01 CTD-2524L6.3 LIN52 MTMR11 SHB TMEM180 TRAF3IP1 Z83851.1
Hair Pigment 0.33 37 28 84.8 -0.08 6.3e-01 AC010883.5 ADCY3 ADD3 ADM AP001601.2 ATG7 ATP2B1 C20orf112 C6orf106 C9orf156 CNTN2 CRHR1 EIF3E EMB ERGIC3 EXOC2 FOXO3 GAB2 HOXB3 HOXB-AS1 ITCH MAP1LC3A MSL1 NFE2L1 NUCKS1 PABPC4 PPP1R3B REST RP11-6N17.6 RP5-1085F17.3 RSL24D1P6 SBF2 SH3D21 SNX11 SPOP SUOX ZNF76
Tanning 0.35 17 12 36.4 0.07 8.0e-01 ADCY3 CNTN2 CTD-2514C3.1 ERGIC3 EXOC2 GAB2 GNL3 ITCH MAP1LC3A NRBF2 OXER1 RP11-137H2.6 RP11-305K5.1 RP11-6N17.6 RP5-1085F17.3 SNX11 SSR3
Hand grip strength (left) 1.55 22 14 42.4 -0.29 1.5e-01 ACTR1A ADCY3 AFAP1 C16orf93 CRHR1 ERGIC3 GSS HOXB2 HOXB3 HOXB-AS1 ITCH LOXL1-AS1 MAP1LC3A MIR3936 NUCKS1 PDLIM4 PEF1 PIP4K2B RPS6KL1 SLC22A4 SLC22A5 SNX11
Number of treatments/medications taken 1.28 5 2 6.1 0.53 3.6e-01 LINC00674 LRP1 RNF38 RPS6KL1 UBA7
Sensitivity / hurt feelings 1.11 3 2 6.1 -0.30 6.2e-01 CRHR1 GLDN PTCH1
Frequency of depressed mood in last 2 weeks 1.06 1 0 0.0 0.00 1.0e+00 SERPING1
Relative age of first facial hair 1.11 5 2 6.1 0.70 1.9e-01 AC004041.2 BRWD1-IT2 CRHR1 FOXO3 VGLL4
Ever had hysterectomy (womb removed) 1.06 1 0 0.0 0.00 1.0e+00 ARL14EP
Systolic blood pressure, automated reading 1.53 28 15 45.5 0.41 3.0e-02 ARHGAP42 ATP2B1 BCAR1 CAMK1D CPEB4 CRHR1 CTA-85E5.10 DMWD EIF2AK4 GNL3 HAUS4 HHIPL1 HTR4 NDUFAF1 NFE2L1 NRBF2 NUDT5 PPP1R3B RBM23 RP11-23P13.4 RP11-6N17.6 SBF2 SNX11 SPINK9 TMEM133 TMEM170A ULK4 VGLL4
Angina 1.21 2 1 3.0 0.00 1.0e+00 CELSR2 GNGT2
Vitamin and mineral supplements 1.14 1 1 3.0 0.00 1.0e+00 LRP1
Medication: Metformin 1.52 3 2 6.1 0.00 1.0e+00 AC010883.5 CAMK1D NUDT5
Diabetes (father) 1.15 1 1 3.0 0.00 1.0e+00 AC010883.5
Diabetes (mother) 1.63 3 3 9.1 0.00 1.0e+00 CAMK1D NUDT5 STARD10
Pack years adult smoking proportion 1.25 1 1 3.0 0.00 1.0e+00 CHRNA5
Impedance of leg (right) 1.59 62 46 139.4 -0.11 3.9e-01 AC010883.5 AC103965.1 ACTR1A ADCY3 ADM ALKBH5 AMPD3 ARVCF ATP6V0D1 BTBD8 C10orf11 C16orf93 C6orf106 CTC-228N24.3 CYBRD1 EHD4 EP300 EPHA2 ERGIC3 EVI5 GNGT2 GNL3 GOLGA6L4 GOLGA6L5 GTF2IRD2 HELLS HSPD1 ITCH KIAA1683 KLF16 LIN52 LSM3 MFAP2 MST1L MST1P2 MTMR11 NEGR1 NEXN NUCKS1 OTUD4 PABPC4 PEAK1 PSTPIP1 PTCH1 RP11-165J3.6 RP11-182J1.16 RP11-23P13.4 RP11-382A20.2 RP11-797A18.4 RPN1 RPS20 SBF2 SCAND2P SH3D21 SHISA4 SUOX TBX6 TMEM170A UBA7 UBE2Q2P1 ZNF74 ZSCAN2
Leg fat-free mass (left) 1.75 62 50 151.5 -0.16 1.7e-01 ACTR1A ADM ARHGEF26 BTBD8 C10orf11 C16orf93 C5orf56 C6orf106 CENPW CPEB4 CTC-228N24.3 CYBRD1 DEF6 DNAJB4 EFEMP1 EPHA2 ERGIC3 FOXO3 GIPC2 GNA12 GPR126 GSS HHIP-AS1 HIVEP2 INTS12 ITCH KLF16 KLHL24 LOXL1-AS1 MAP1LC3A MIR3936 MSL1 NEGR1 NEXN NUCKS1 OTUD4 PABPC4 PDE2A PDLIM4 PEF1 PIP4K2B PLEKHA1 PPA2 PTCH1 RP11-361D14.2 RP11-435O5.5 RP11-506H20.1 RPL10A RPN1 RPS20 SBF2 SH3D21 SHISA4 SLC22A4 SLC22A5 SMPD2 SNX11 SUOX TBX6 UBA7 UQCRQ ZNF76
Trunk fat percentage 1.30 39 23 69.7 -0.35 2.4e-02 AC103965.1 ADCY3 ADM C16orf93 C6orf106 CCDC171 CENPW CPD CRHR1 DNAJC11 FAM13A FOXO3 GNA12 GNGT2 GOLGA6L4 GOLGA6L5 HTR4 IQCH KIAA1683 KLHL24 LINC00674 NDUFAF1 NEGR1 NTM OTUD4 OXER1 PABPC4 RARB RP11-182J1.16 RP11-810M2.2 RP11-95P2.1 RPS6KL1 SBF2 SCAND2P SHISA4 SNX11 UBE2Q2P1 ZSCAN2 ZZEF1
Hand grip strength (right) 1.63 21 15 45.5 -0.43 3.1e-02 ACTR1A ADCY3 AFAP1 C16orf93 CRHR1 DNAJB4 ERGIC3 GSS HOXB2 HOXB3 HOXB-AS1 ITCH LOXL1-AS1 MAP1LC3A MIR3936 NUCKS1 PDLIM4 PEF1 PIP4K2B SLC22A4 SLC22A5
Current tobacco smoking 1.16 1 1 3.0 0.00 1.0e+00 ACTR1A
Maternal smoking around birth 1.19 2 1 3.0 0.00 1.0e+00 ACTR1A TSPAN14
Fed-up feelings 1.09 4 2 6.1 0.58 4.2e-01 AC113608.1 CRHR1 RPS6KL1 UBA7
Relative age voice broke 0.95 3 2 6.1 0.00 1.0e+00 CRHR1 FOXO3 RP11-95P2.1
Taking other prescription medications 1.21 3 2 6.1 0.00 1.0e+00 MSL1 RPS6KL1 UBA7
Age when periods started (menarche) 1.22 14 10 30.3 -0.07 8.2e-01 ADCY3 BRWD1-IT2 CENPW COG6 EEFSEC FOXO3 GAB2 GNL3 KLF16 NEGR1 NUCKS1 PAN3-AS1 SUOX UBA7
Bilateral oophorectomy (both ovaries removed) 1.05 1 1 3.0 0.00 1.0e+00 ARL14EP
Heel bone mineral density (BMD) T-score, automated (left) 1.36 15 6 18.2 0.16 5.4e-01 BMP4 EP300 FAM213A FAM3C HHIP-AS1 LACTB2 LTBP3 MRC2 OTUD4 PPP1R3B REST RP11-137H2.6 RP11-165J3.6 RP11-435O5.5 SERTAD2
High blood pressure 1.46 19 11 33.3 0.46 4.0e-02 ARHGAP42 ATP2B1 C1GALT1 CEP41 DNAJC11 EEFSEC GNGT2 HTR4 KB-1107E3.1 MET MIR3936 NEGR1 NRBF2 RP11-810M2.2 RUVBL1 SLC22A5 SUOX TMEM133 VGLL4
Hayfever, allergic rhinitis or eczema 1.61 18 14 42.4 0.82 1.4e-06 AC114730.7 BACH2 C1orf43 C6orf106 FOXO1 IL18R1 MSL1 NDUFAF1 ORMDL3 PDLIM4 RBBP8 SLC22A4 SLC22A5 SMAD3 SUOX THRA TOM1L2 UQCRQ
Multivitamins +/- minerals 1.17 2 1 3.0 0.00 1.0e+00 KIF1B NUCKS1
Supplements: Glucosamine 1.08 1 1 3.0 0.00 1.0e+00 NRBF2
Medication: Atenolol 1.15 1 0 0.0 0.00 1.0e+00 MET
Medication: Levothyroxine sodium 1.26 4 3 9.1 0.22 7.8e-01 ATP6V0D1 BACH2 C9orf156 SUOX
Sitting height 2.32 94 70 212.1 0.06 5.3e-01 AC007319.1 AC074212.6 AC103965.1 ADCY3 ADM AFAP1 BOK BTBD8 C10orf11 C5orf56 C6orf106 C9orf156 CALCRL CCDC171 CDON CENPW COX7A2L CRHR1 CYBRD1 DEPTOR DMWD DNAJB4 DRAM1 EFEMP1 EIF2AK4 ERC1 ERGIC3 EVI5 FAM171B FBXL8 FOXO3 FRK FUT2 GIPC2 GLDN GNA12 GNGT2 GNPTAB GOLGA6L4 GOLGA6L5 GPR126 GSS GYPA GYPE HELLS HHIP-AS1 HIVEP2 HOXB-AS1 INTS12 ISCA1 ITCH LOXL1-AS1 LRP1 LRRC37B MAP1LC3A MARCH2 MFAP2 MIR3936 MRC2 MSL1 MST1L MST1P2 MTMR11 MUTYH NEXN NUCKS1 OTUD4 PDE2A PDLIM4 PIP4K2B PLEKHA1 PPA2 PPP1R3B PTCH1 RP11-182J1.16 RP11-361D14.2 RP11-425D10.10 RP11-435O5.5 RP11-506H20.1 RP11-506M13.3 RP11-95P2.1 RPL10A RPS20 SBF2 SLC22A4 SLC22A5 SMPD2 ST3GAL4 STRA13 TMEM165 UBE2Q2P1 UQCRQ VGLL4 ZSCAN2
Chronic bronchitis/emphysema (father) 1.47 1 1 3.0 0.00 1.0e+00 CHRNA5
High blood pressure (mother) 1.28 3 1 3.0 0.00 1.0e+00 DNAJC11 FLJ12825 TMEM170A
Body mass index (BMI) 1.25 36 20 60.6 -0.34 4.2e-02 ACTR1A ADCY3 BRWD1-IT2 C16orf93 C6orf106 CCDC171 DNAJB4 DNAJC11 EEFSEC EP300 EVI5 FOSB FOXO3 GIPC2 GNL3 HSPD1 HTR4 ITCH KIAA1683 KLF16 LINC00674 MUTYH NEGR1 NEXN NFE2L1 OTUD4 PABPC4 PPP1R3B RP11-797A18.4 RP1-18D14.7 RP3-395M20.9 RPL10A SHISA4 SUOX TBX6 UBA7
Impedance of leg (left) 1.60 67 48 145.5 -0.03 7.8e-01 AC010883.5 AC103965.1 ACTR1A ADCY3 ADM ALKBH5 AMPD3 ARVCF ATP6V0D1 BTBD8 C10orf11 C16orf93 C6orf106 CEP41 CTC-228N24.3 CYBRD1 EHD4 EP300 EPHA2 ERGIC3 EVI5 FARP2 GNGT2 GNL3 GOLGA6L4 GOLGA6L5 GPR126 GTF2IRD2 HELLS HSPD1 ITCH KLF16 LIN52 LSM3 MFAP2 MST1L MST1P2 MTMR11 NEGR1 NEXN NUCKS1 OTUD4 PABPC4 PEAK1 PSTPIP1 PTCH1 RP11-165J3.6 RP11-182J1.16 RP11-23P13.4 RP11-382A20.2 RP11-673E1.3 RP11-797A18.4 RPN1 RPS20 RPS6KL1 SBF2 SCAND2P SH3D21 SHISA4 SMPD2 SUOX TBX6 TMEM170A UBA7 UBE2Q2P1 ZNF74 ZSCAN2
Leg predicted mass (left) 1.74 62 49 148.5 -0.16 1.7e-01 ACTR1A ADM ARHGEF26 BTBD8 C10orf11 C16orf93 C5orf56 C6orf106 CENPW CPEB4 CTC-228N24.3 CYBRD1 DEF6 DNAJB4 EFEMP1 EPHA2 ERGIC3 FOXO3 GIPC2 GNA12 GPR126 GSS HHIP-AS1 HIVEP2 INTS12 ITCH KLF16 KLHL24 LOXL1-AS1 MAP1LC3A MIR3936 MSL1 NEGR1 NEXN NUCKS1 OTUD4 PABPC4 PDE2A PDLIM4 PEF1 PIP4K2B PLEKHA1 PPA2 PTCH1 RP11-361D14.2 RP11-435O5.5 RP11-506H20.1 RPL10A RPN1 RPS20 SBF2 SH3D21 SHISA4 SLC22A4 SLC22A5 SMPD2 SNX11 SUOX TBX6 UBA7 UQCRQ ZNF76
Trunk fat mass 1.39 47 31 93.9 -0.26 5.9e-02 AC103965.1 ADCY3 ARHGEF26 C16orf93 C6orf106 CCDC171 CPD CRHR1 DNAJB4 DNAJC11 ERGIC3 FOXO3 GIPC2 GNA12 GNGT2 GOLGA6L4 GOLGA6L5 GPR126 HIVEP2 HTR4 IQCH ITCH KB-1107E3.1 KIAA1683 KLF16 KLHL24 LINC00674 NEGR1 NEXN OTUD4 PABPC4 PLEKHA1 RARB RP11-182J1.16 RP11-361D14.2 RP11-810M2.2 RP1-18D14.7 RP11-95P2.1 RPL10A SCAND2P SHISA4 SNX11 TBX6 UBA7 UBE2Q2P1 ZSCAN2 ZZEF1
Waist circumference 1.33 37 23 69.7 -0.28 7.5e-02 AC007319.1 ADCY3 ARL14EP C16orf93 C6orf106 CALCRL CCDC171 DNAJB4 DNAJC11 FOSB FOXO3 GIPC2 GOLGA6L4 HOXB2 HOXB3 HTR4 IQCH KB-1107E3.1 KIAA1683 KLF16 LINC00674 MICU3 MLLT10 NEGR1 OTUD4 PABPC4 RP11-182J1.16 RP11-810M2.2 RP3-395M20.9 RPL10A SHISA4 SNX11 SUOX TBX6 UBA7 ZSCAN2 ZZEF1
Number of incorrect matches in round 1.16 1 0 0.0 0.00 1.0e+00 TSPAN14
Past tobacco smoking 1.19 5 3 9.1 -0.63 2.5e-01 ACTR1A IQCH REST TMEM180 TOP2B
Alcohol usually taken with meals 1.12 3 1 3.0 0.00 1.0e+00 ACTR1A NEGR1 SERPING1
Nervous feelings 1.06 7 3 9.1 0.72 6.7e-02 ACTR1A CENPW CRHR1 GNL3 PPP1R3B RPS6KL1 SBF2
Frequency of tenseness / restlessness in last 2 weeks 0.94 2 1 3.0 0.00 1.0e+00 CRHR1 UBA7
Hearing difficulty/problems with background noise 1.09 1 1 3.0 0.00 1.0e+00 NUCKS1
Hair/balding pattern: Pattern 2 1.08 2 1 3.0 0.00 1.0e+00 C10orf11 CRHR1
Forced vital capacity (FVC) 2.34 69 45 136.4 0.18 1.2e-01 ADCY3 BMF BOK C10orf11 CAMK1D CCDC171 CDC123 CENPW CHRNA5 CRHR1 CTA-85E5.10 CTC-228N24.3 CTCF CYB5R3 CYBRD1 DEF6 DEPTOR EFEMP1 EIF2AK4 ERC1 ERGIC3 FARP2 GIPC2 GNA12 GOLGA6L5 GPR126 GYPA HHIP-AS1 HIVEP2 HTR4 INTS12 IQCH LONRF2 LOXL1-AS1 MFAP2 MST1L MST1P2 MTERFD2 NFE2L1 NUDT5 OTUD4 PCSK7 PIP4K2B PLEKHA1 PPA2 PSTPIP1 PTCH1 RAPH1 REST RP11-108M9.5 RP11-182J1.16 RP11-361D14.2 RP11-382A20.2 RP11-435O5.5 RP11-6N17.6 RP11-797A18.4 RPL10A RPS20 RRP15 SH3D21 SHKBP1 SLMAP SMPD2 SMURF2 SSH2 UBA7 UBE2Q2P1 UBE2R2 ZNF76
Heel bone mineral density (BMD) T-score, automated (right) 1.39 10 6 18.2 0.02 9.4e-01 BMP4 EPHA2 FAM213A FAM3C HHIP-AS1 PPP1R3B REST RP11-165J3.6 SERTAD2 ZNF76
Ever unenthusiastic/disinterested for a whole week 0.95 1 0 0.0 0.00 1.0e+00 UBA7
Qualifications: None of the above 1.09 6 4 12.1 -0.08 8.7e-01 ACTR1A FOXO3 LIN52 NEGR1 SUOX UBA7
Mouth/teeth dental problems 1.08 1 0 0.0 0.00 1.0e+00 FUT2
Heart attack 1.14 1 1 3.0 0.00 1.0e+00 CELSR2
Allergy 2.06 23 18 54.5 -0.82 1.1e-07 AC114730.7 BACH2 C1orf43 C5orf56 C6orf106 FOXO1 IL18R1 IL33 IQCH LRP1 MIR3936 MSL1 NDUFAF1 ORMDL3 PDLIM4 RBBP8 RP5-1085F17.3 SLC22A4 SLC22A5 SMAD3 SUOX THRA UQCRQ
Diabetes (self-reported) 1.35 2 1 3.0 0.00 1.0e+00 AC010883.5 C1GALT1
Hayfever/allergic rhinitis (self-reported) 1.52 6 3 9.1 0.99 1.7e-04 AC114730.7 BACH2 IL18R1 ORMDL3 SMAD3 SUOX
Medication: Ramipril 1.25 1 0 0.0 0.00 1.0e+00 TMEM133
Medication: Simvastatin 1.22 3 2 6.1 0.00 1.0e+00 CELSR2 DMWD FUT2
Fluid intelligence score 1.09 8 4 12.1 -0.42 2.6e-01 ALKBH5 BTG3 FOXO3 NEGR1 PEF1 PPA2 RARB UBA7
Illnesses of siblings 1.25 1 0 0.0 0.00 1.0e+00 SSH2
Neuroticism score 1.18 7 3 9.1 0.38 3.6e-01 ADM CRHR1 PPP1R3B PTCH1 RPS6KL1 SBF2 SERPING1
Weight 1.56 61 43 130.3 -0.33 5.0e-03 AC103965.1 ACTR1A ADCY3 ARHGEF26 BOK C16orf93 C6orf106 CCDC171 CENPW DNAJB4 EFEMP1 ERGIC3 FOSB FOXO1 FOXO3 GIPC2 GNA12 GOLGA6L4 GOLGA6L5 GPR126 GSS HHIP-AS1 HIVEP2 HTR4 INTS12 IQCH ITCH KB-1107E3.1 KLF16 KLHL24 LINC00674 MAP1LC3A MIR3936 NEGR1 NEXN NUCKS1 OTUD4 PABPC4 PDE2A PEF1 PLEKHA1 PPA2 RP11-182J1.16 RP11-361D14.2 RP11-435O5.5 RP11-810M2.2 RP1-18D14.7 RP11-95P2.1 RP3-395M20.9 RPL10A RPS20 SHISA4 SLC22A5 SMPD2 SNX11 SUOX TBX6 TRMT61B UBA7 UBE2Q2P1 ZSCAN2
Impedance of arm (right) 1.51 58 40 121.2 0.24 5.5e-02 AC103965.1 ACTR1A ADM AMPD3 ARVCF C10orf11 C6orf106 CENPW CHD3 CRHR1 DNAJB4 EEFSEC EHD4 EP300 FLJ12825 FOSB FOXO3 GAB2 GIPC2 GNGT2 GNL3 GOLGA6L4 GOLGA6L5 GPR126 GTF2IRD2 ITCH LOC342346 LOXL1-AS1 MARCH2 MFAP2 MST1L MST1P2 MTMR11 NEGR1 NEXN NFE2L1 NRBF2 NUCKS1 PEF1 PPP1R3B PSTPIP1 RAB7A RIF1 RP11-108M9.5 RP11-182J1.16 RP11-797A18.4 RP3-395M20.9 RPL10A RPS20 SBF2 SCAND2P SHISA4 SMAD3 SUOX TBX6 UBA7 UBE2Q2P1 ZNF354C
Arm fat percentage (right) 1.19 28 17 51.5 -0.10 6.0e-01 ADCY3 ADM AFAP1 C16orf93 C6orf106 CCDC171 CENPW CPD DNAJC11 HSPD1 HTR4 IQCH KIAA1683 KLF16 KLHL24 LINC00674 NDUFAF1 NEGR1 OXER1 PABPC4 RARB RP1-18D14.7 SBF2 SHISA4 SSH2 SSR3 TBX6 UBA7
Trunk fat-free mass 1.92 65 54 163.6 -0.14 2.0e-01 ACTR1A ADM AMPD3 BTBD8 C10orf11 C5orf56 C6orf106 CENPW CTC-228N24.3 CYBRD1 DEF6 DNAJB4 EFEMP1 ERGIC3 FOXO3 GIPC2 GNA12 GPR126 GSS HHIP-AS1 HIVEP2 INTS12 ITCH LOC342346 LOXL1-AS1 MAP1LC3A MARCH2 MET MFAP2 MIR3936 MSL1 MST1P2 NEXN NUCKS1 OTUD4 PABPC4 PDE2A PDLIM4 PEF1 PIP4K2B PLEKHA1 PPA2 PTCH1 RBBP8 REST RP11-182J1.16 RP11-361D14.2 RP11-435O5.5 RP11-506H20.1 RPL10A RPS20 RPS6KL1 SBF2 SH3D21 SHISA4 SLC22A4 SLC22A5 SMPD2 SNX11 SNX33 SUOX TBX6 UBA7 UQCRQ ZNF76
Hip circumference 1.41 50 36 109.1 -0.13 3.3e-01 AC103965.1 ACTR1A ADCY3 ALKBH5 ARHGEF26 BOK C16orf93 C6orf106 CCDC171 CPEB4 CYBRD1 DNAJB4 ERGIC3 FOXO3 GIPC2 GNA12 GOLGA6L4 GPR126 HHIP-AS1 HIVEP2 HTR4 ITCH KB-1107E3.1 KLF16 KLHL24 LINC00674 NEGR1 NEXN OTUD4 PABPC4 PEF1 PLEKHA1 PPA2 PPP1R3B PTCH1 RP11-182J1.16 RP11-361D14.2 RP11-435O5.5 RP1-18D14.7 RP11-95P2.1 RPL10A RPS20 SCAND2P SHISA4 SMPD2 SNX11 TBX6 TRMT61B UBA7 ZSCAN2
Alcohol intake versus 10 years previously 1.02 2 0 0.0 0.00 1.0e+00 NEGR1 PABPC4
Father's age at death 1.18 1 0 0.0 0.00 1.0e+00 CHRNA5
Worrier / anxious feelings 1.10 6 4 12.1 0.25 5.9e-01 ACTR1A CRHR1 PPP1R3B PTCH1 RPS6KL1 SERPING1
Frequency of tiredness / lethargy in last 2 weeks 1.03 1 0 0.0 0.00 1.0e+00 SERPING1
Hair/balding pattern: Pattern 3 1.11 3 2 6.1 0.00 1.0e+00 CENPW CRHR1 MAP1LC3A
Number of live births 1.19 1 0 0.0 0.00 1.0e+00 CRHR1
Forced expiratory volume in 1-second (FEV1) 2.94 84 56 169.7 -0.68 4.8e-15 AC103965.1 ADAM19 ADCY3 AFAP1 AFAP1L1 BCAR1 BOK C10orf11 C1GALT1 C20orf112 CAMK1D CCDC171 CCDC7 CDC123 CENPW CHRNA5 CRHR1 CTA-85E5.10 CTD-2524L6.3 DEF6 DNAJB4 DNALI1 EFEMP1 ERGIC3 FAM149B1 FAM168A GIPC2 GM2A GOLGA6L4 GOLGA6L5 GYPA HHIP-AS1 HTR4 INTS12 KIAA0802 KPNA3 LLGL2 LONRF2 LOXL1-AS1 LRRC37B MFAP2 MICAL3 MIR3936 MRPS16 MST1L MST1P2 NEXN NRBF2 NUDT5 OTUD4 PCGF2 PPA2 PTCH1 REST RP11-1277A3.3 RP11-182J1.16 RP11-361D14.2 RP11-382A20.2 RP11-425D10.10 RP11-435O5.5 RP11-541N10.3 RP11-680F20.12 RP11-800A3.7 RP11-809N8.4 RPL10A RPS20 RSL24D1P6 RUVBL1 SCAND2P SCGB1A1 SEC61A2 SLC22A5 SLMAP SMPD2 SMURF2 SOGA2 SPINK9 SUOX SYNM THSD4 UBA7 UBE2Q2P1 ZNF76 ZSCAN2
Pulse rate 1.15 2 2 6.1 0.00 1.0e+00 GJA1 PPP1R3E
Qualifications: A levels/AS levels or equivalent 0.96 7 2 6.1 0.19 6.9e-01 ACTR1A CRHR1 GPD2 KIAA1683 NEGR1 SUOX UBA7
Mouth/teeth dental problems: Dentures 1.16 2 0 0.0 0.00 1.0e+00 EIF2AK4 FUT2
Asthma 2.68 28 20 60.6 0.73 2.1e-06 AC114730.7 ADAM19 BACH2 C16orf93 C5orf56 DMWD EEFSEC GNGT2 HTR4 IL18R1 IL33 IQCH LRP1 LTBP3 MIR3936 MSL1 ORMDL3 PDLIM4 RUVBL1 SLC22A4 SLC22A5 SMAD3 SRGAP2 SUOX THRA UQCRQ YRDC ZNF76
Medication: Ibuprofen (e.g. Nurofen) 1.17 1 1 3.0 0.00 1.0e+00 LRP1
Medication: Cholesterol lowering 1.31 2 1 3.0 0.00 1.0e+00 CELSR2 DNAJC11
Prospective memory result 1.15 1 0 0.0 0.00 1.0e+00 PEF1
Lung cancer (father) 0.98 1 1 3.0 0.00 1.0e+00 CHRNA5
Forced expiratory volume in 1-second (FEV1), Best measure 2.99 81 55 166.7 -0.74 3.1e-18 AC103965.1 ADAM19 ADCY3 AFAP1 AFAP1L1 AP1B1 BCAR1 BOK C10orf11 C1GALT1 C20orf112 CAMK1D CCDC7 CDC123 CENPW CHRNA5 CRHR1 CTA-85E5.10 CTD-2524L6.3 DEF6 DNAJB4 DNALI1 DRAM2 EFEMP1 ERGIC3 FAM168A FRK GIPC2 GM2A GOLGA6L4 GOLGA6L5 GYPA HHIP-AS1 HTR4 INTS12 KIAA0802 KPNA3 LLGL2 LONRF2 LOXL1-AS1 LRRC37B MFAP2 MICAL3 MIR3936 MRPS16 MST1L MST1P2 NEXN NRBF2 NUDT5 OTUD4 PAIP1 PCGF2 PPA2 REST RP11-1277A3.3 RP11-182J1.16 RP11-361D14.2 RP11-382A20.2 RP11-809N8.4 RPL10A RPS20 RSL24D1P6 RUVBL1 SCAND2P SCGB1A1 SEC61A2 SLC22A5 SLMAP SMPD2 SMURF2 SOGA2 SPINK9 SUOX SYNM TBX3 THSD4 UBA7 UBE2Q2P1 ZNF76 ZSCAN2
Impedance of arm (left) 1.52 59 39 118.2 0.19 1.3e-01 AC103965.1 ACTR1A ADM AMPD3 C10orf11 C6orf106 CENPW CHD3 CRHR1 DNAJB4 DNALI1 EEFSEC EP300 EVI5 FLJ12825 FOSB FOXO3 GAB2 GIPC2 GNA12 GNGT2 GNL3 GOLGA6L4 GOLGA6L5 GPR126 GTF2IRD2 ITCH LOC342346 LOXL1-AS1 LSM3 MARCH2 MFAP2 MRPL52 MST1L MST1P2 MTMR11 NEGR1 NEXN NFE2L1 NRBF2 PEF1 PPP1R3B PSTPIP1 RIF1 RP11-108M9.5 RP11-182J1.16 RP11-797A18.4 RP3-395M20.9 RPL10A RPS20 RUVBL1 SBF2 SCAND2P SHISA4 SUOX TBX6 UBA7 UBE2Q2P1 ZNF354C
Arm fat mass (right) 1.25 33 21 63.6 -0.35 3.7e-02 ADCY3 ARHGEF26 C16orf93 C6orf106 CCDC171 CPD DNAJB4 DNAJC11 ERGIC3 FOSB FOXO3 GIPC2 HSPD1 HTR4 IQCH ITCH KIAA1683 KLF16 KLHL24 LINC00674 NEGR1 NEXN OTUD4 PABPC4 RP11-810M2.2 RP1-18D14.7 RP3-395M20.9 RPL10A SHISA4 SNX11 SUOX TBX6 UBA7
Trunk predicted mass 1.91 62 53 160.6 -0.16 1.8e-01 ACTR1A ADM AMPD3 BTBD8 C10orf11 C5orf56 C6orf106 CENPW CTC-228N24.3 CYBRD1 DEF6 DNAJB4 EFEMP1 ERGIC3 FOXO3 GIPC2 GNA12 GPR126 GSS HHIP-AS1 HIVEP2 INTS12 ITCH LOC342346 LOXL1-AS1 MAP1LC3A MARCH2 MIR3936 MSL1 MST1P2 NEXN NUCKS1 OTUD4 PABPC4 PDE2A PDLIM4 PEF1 PIP4K2B PLEKHA1 PPA2 PTCH1 RBBP8 REST RP11-361D14.2 RP11-435O5.5 RP11-506H20.1 RPL10A RPS20 RPS6KL1 SBF2 SH3D21 SHISA4 SLC22A4 SLC22A5 SMPD2 SNX11 SNX33 SUOX TBX6 UBA7 UQCRQ ZNF76
Standing height 2.30 132 111 336.4 0.09 2.4e-01 AC074212.6 AC103965.1 ADAM17 ADCY3 ADM AFAP1 ALKBH5 ATP6V0D1 BOK BTBD8 C5orf56 C6orf106 C9orf156 CABLES2 CCDC144B CENPW CHD3 COG6 CRHR1 CTCF CYBRD1 DEF6 DEPTOR DMWD DRAM1 EFEMP1 ERC1 ERGIC3 EVI5 FARP2 FOXO3 FRK FTOP1 FUT2 GIPC2 GNA12 GNGT2 GNL3 GNPTAB GOLGA6L4 GOLGA6L5 GPR126 GRK5 GSS GYPE HHIP-AS1 HIVEP2 HOXB-AS1 IL33 INTS12 ISCA1 ITCH KIAA0753 KIF1B KPNA3 LIN52 LLGL2 LOX LOXL1-AS1 LRP1 LRRC37B LSM3 MAP1LC3A MARCH2 MFAP2 MIR3936 MRC2 MRPS6 MSL1 MST1L MST1P2 MTMR11 MUTYH NBPF1 NDUFAF1 NEXN NFE2L1 NUCKS1 OTUD4 PABPC4 PADI2 PDE2A PDLIM4 PEAK1 PIP4K2B PLEKHA1 PPA2 PSTPIP1 PTCH1 QPCTL RANBP10 RBBP8 REST RP11-108M9.5 RP11-1277A3.3 RP11-165J3.6 RP11-182J1.16 RP11-361D14.2 RP11-382A20.2 RP11-425D10.10 RP11-435O5.5 RP11-506H20.1 RP11-673E1.3 RP11-6N17.6 RP11-797A18.4 RP11-95P2.1 RPL10A RPS20 RPS6KL1 RRP15 SBF2 SCAND2P SH3D21 SLC22A4 SLC22A5 SLC2A9 SMPD2 SMURF2 SNX11 SOX9 SSH2 ST3GAL4 STRA13 TBX6 TMEM170A TRAF3IP1 UBE2Q2 UBE2Q2P1 UQCRQ ZNF354C ZNF76 ZSCAN2
Exposure to tobacco smoke at home 0.90 1 1 3.0 0.00 1.0e+00 UBA7
Tense / 'highly strung' 1.06 2 0 0.0 0.00 1.0e+00 NUCKS1 RPS6KL1
Seen doctor (GP) for nerves, anxiety, tension or depression 1.12 2 1 3.0 0.00 1.0e+00 NEGR1 RPS6KL1
Hair/balding pattern: Pattern 4 1.15 9 7 21.2 0.09 8.1e-01 ATP6V0D1 C10orf11 CENPW CRHR1 CTCF GSS ITCH RANBP10 RIOK1
Birth weight of first child 1.50 6 3 9.1 -0.76 4.5e-02 OTUD4 PPA2 RP11-361D14.2 SESN1 SUOX TMEM170A
Peak expiratory flow (PEF) 2.79 42 22 66.7 -0.91 6.4e-19 AC010883.5 ADAM19 BCAR1 BMP4 C10orf11 C1GALT1 CAMK1D CCDC7 CDC123 CPD CRHR1 CTA-85E5.10 DNAJB4 ERGIC3 FAM168A FUT2 GIPC2 GSS GYPA HHIP-AS1 HOXB2 HOXB-AS1 HTR4 MAP1LC3A NEXN NUCKS1 NUDT5 OTUD4 PPA2 RARB REST RP11-361D14.2 RP11-800A3.7 SBSPON SEC61A2 SMPD2 SPINK9 SSH2 TCTN2 THSD4 TMEM170A ZNF76
Pulse wave reflection index 1.18 1 0 0.0 0.00 1.0e+00 PPP1R3E
Blood clot in the leg (DVT) 1.21 2 1 3.0 0.00 1.0e+00 ERGIC3 NME7
Medication: Paracetamol 1.24 3 2 6.1 0.00 1.0e+00 CRHR1 LRP1 UBA7
Headache pain in last month 1.47 9 3 9.1 -0.02 9.6e-01 BCAR1 CRHR1 DMWD LRP1 PPP1R3B SERPING1 SLC24A3 SUOX TMEM170A
Medication for cholesterol, blood pressure or diabetes 1.33 5 4 12.1 -0.21 7.3e-01 ATP2B1 CAMK1D CELSR2 DNAJC11 TMEM133
Glaucoma (self-reported) 1.11 1 1 3.0 0.00 1.0e+00 AFAP1
Hypothyroidism/myxoedema (self-reported) 1.26 8 6 18.2 -0.24 5.7e-01 ATP6V0D1 BACH2 C9orf156 CTCF PLEKHA1 PPP1R3B SESN1 SUOX
Medication: Ventolin 100micrograms inhaler 1.81 4 3 9.1 0.99 1.3e-02 FOXO1 IL18R1 ORMDL3 SMAD3
Birth weight 1.64 14 6 18.2 0.01 9.7e-01 ASCC2 CENPW DEF6 FCGR2B GNA12 GPR126 NUCKS1 PPA2 PTCH1 RP11-361D14.2 RP11-425D10.10 RP11-435O5.5 SESN1 SHB
Chronic bronchitis/emphysema (mother) 1.36 3 0 0.0 0.00 1.0e+00 CHRNA5 HHIP-AS1 RARB
High blood pressure (siblings) 1.25 2 1 3.0 0.00 1.0e+00 NRBF2 TMEM133
Forced vital capacity (FVC), Best measure 2.27 65 37 112.1 0.15 2.0e-01 AC103965.1 ADCY3 BMF BOK BTBD8 C10orf11 C5orf63 CCDC171 CDC123 CENPW CHRNA5 CRHR1 CTA-85E5.10 CYBRD1 DEF6 DRAM1 EFEMP1 ERC1 ERGIC3 FARP2 GIPC2 GNA12 GOLGA6L5 GPR126 GYPA HHIP-AS1 HIVEP2 HTR4 INTS12 IQCH LONRF2 LOXL1-AS1 MFAP2 MSL1 MST1L MST1P2 MTERFD2 NFE2L1 NUDT5 OTUD4 PCSK7 PIP4K2B PPA2 PSTPIP1 PTCH1 REST RP11-108M9.5 RP11-182J1.16 RP11-361D14.2 RP11-382A20.2 RP11-435O5.5 RP11-6N17.6 RP11-797A18.4 RPL10A RPS20 RRP15 SH3D21 SHKBP1 SMPD2 SMURF2 SSH2 SYNM UBA7 UBE2Q2P1 ZNF76
Body fat percentage 1.31 40 22 66.7 -0.39 1.1e-02 AC103965.1 ADCY3 ADM C16orf93 C6orf106 CCDC171 CENPW CPD CTC-228N24.3 DNAJC11 FOXO3 GNGT2 GOLGA6L4 GOLGA6L5 HTR4 IQCH KIAA1683 KLF16 KLHL24 LINC00674 NDUFAF1 NEGR1 NTM OXER1 RARB RP11-165J3.6 RP11-182J1.16 RP11-810M2.2 RP1-18D14.7 RP11-95P2.1 RPS6KL1 SBF2 SCAND2P SHISA4 SSH2 SYNM UBA7 UBE2Q2P1 ZSCAN2 ZZEF1
Leg fat percentage (right) 1.47 39 18 54.5 -0.53 5.5e-04 ADCY3 ADM C6orf106 CALCRL CCDC171 CENPW CPD CTC-228N24.3 DNAJB4 DNAJC11 ERGIC3 FOSB GIPC2 GOLGA6L4 GRK5 HTR4 IQCH KIAA1683 LINC00674 LRP1 MLLT10 MUTYH NDUFAF1 NEGR1 NFE2L1 PRIM2 RP11-165J3.6 RP11-182J1.16 RP11-435O5.5 RP11-810M2.2 RP11-95P2.1 RP3-395M20.9 RPS6KL1 SBF2 SCAND2P SHISA4 SSH2 UBA7 ZZEF1
Arm fat-free mass (right) 1.83 60 44 133.3 -0.21 7.0e-02 ACTR1A ADM ARHGEF26 BTBD8 C10orf11 C16orf93 C6orf106 CENPW CPEB4 CYBRD1 DEF6 DNAJB4 EFEMP1 ERGIC3 FOXO3 GIPC2 GNA12 GPR126 GSS HHIP-AS1 HIVEP2 INTS12 ITCH LOC342346 LOXL1-AS1 LRRC29 MAP1LC3A MARCH2 MET MIR3936 NEGR1 NEXN NUCKS1 OTUD4 PABPC4 PDE2A PDLIM4 PEF1 PIP4K2B PLEKHA1 PPA2 PTCH1 RBBP8 REST RP11-361D14.2 RP11-435O5.5 RP11-506H20.1 RP3-395M20.9 RPL10A RPS20 SBF2 SH3D21 SHISA4 SLC22A4 SLC22A5 SMPD2 SUOX TBX6 UBA7 ZNF76
Comparative body size at age 10 1.58 19 10 30.3 -0.45 4.6e-02 ADCY3 ATP6V0D1 C16orf93 CALCRL DNAJC11 EP300 FAM171B FHOD1 FOSB FUT2 GNGT2 GOLGA6L4 LRRC29 MED7 NEGR1 NUCKS1 PAN3-AS1 PPP1R3B VGLL4
Worry too long after embarrassment 1.06 2 0 0.0 0.00 1.0e+00 CRHR1 SERPING1
Wheeze or whistling in the chest in last year 1.71 10 6 18.2 0.84 3.5e-04 AC114730.7 ADAM19 BACH2 IL18R1 IL33 MSL1 ORMDL3 SMAD3 THRA UBA7
Age at first live birth 1.06 2 2 6.1 0.00 1.0e+00 MLTK UBA7
Qualifications: College or University degree 1.10 20 9 27.3 0.00 9.8e-01 ACTR1A ASCC2 CCDC144B CRHR1 FOXO3 GANAB HAUS4 KIAA1683 MAP1LC3A MET MTMR3 NEGR1 PPA2 RBM23 SHISA4 SUOX TIGD2 UBA7 UQCR10 VTA1
Eye problems/disorders: None of the above 1.06 1 0 0.0 0.00 1.0e+00 USP40
Medication for pain relief, constipation, heartburn 1.24 4 2 6.1 -0.99 7.6e-03 CRHR1 LRP1 NUCKS1 RPS6KL1
Medication: Blood pressure 1.34 6 3 9.1 0.34 5.0e-01 ARHGAP42 ATP2B1 CEP41 DNAJC11 RP11-810M2.2 TMEM133
Angina (self-reported) 1.20 2 1 3.0 0.00 1.0e+00 CELSR2 GNGT2
Migraine (self-reported) 1.18 2 1 3.0 0.00 1.0e+00 LRP1 SLC24A3
Medication: Ibuprofen 1.14 1 1 3.0 0.00 1.0e+00 LRP1
Medication: Seretide 50 evohaler 1.50 5 1 3.0 0.98 5.5e-04 IL18R1 MIR3936 PDLIM4 SLC22A4 SLC22A5
Mean time to correctly identify matches 1.10 5 1 3.0 0.66 1.6e-01 DNAJB4 FOXO3 GIPC2 NUCKS1 RP11-810M2.2
Whole body fat mass 1.35 44 29 87.9 -0.33 2.1e-02 AC103965.1 ADCY3 ARHGEF26 C16orf93 C6orf106 CCDC171 DNAJB4 DNAJC11 ERGIC3 FOSB FOXO3 GIPC2 GNA12 GOLGA6L4 GOLGA6L5 GPR126 HTR4 IQCH ITCH KB-1107E3.1 KIAA1683 KLF16 KLHL24 LINC00674 NEGR1 NEXN OTUD4 PABPC4 RP11-182J1.16 RP11-361D14.2 RP11-810M2.2 RP1-18D14.7 RP11-95P2.1 RP3-395M20.9 RPL10A SCAND2P SHISA4 SNX11 SUOX TBX6 UBA7 UBE2Q2P1 ZSCAN2 ZZEF1
Leg fat mass (right) 1.38 42 25 75.8 -0.49 4.1e-04 AC103965.1 ACTR1A ADCY3 ARHGEF26 C16orf93 C6orf106 CCDC171 CPD DNAJB4 DNAJC11 FOSB FOXO3 GIPC2 GOLGA6L4 HTR4 IQCH ITCH KB-1107E3.1 KIAA1683 KLF16 KLHL24 LINC00674 MLLT10 NEGR1 NEXN OTUD4 PABPC4 PEF1 PPP1R3B RP11-182J1.16 RP11-810M2.2 RP1-18D14.7 RP11-95P2.1 RP3-395M20.9 RPL10A SHISA4 SSH2 SUOX TBX6 UBA7 ZSCAN2 ZZEF1
Arm predicted mass (right) 1.82 61 45 136.4 -0.22 6.6e-02 ACTR1A ADM ARHGEF26 ARVCF BTBD8 C10orf11 C16orf93 C6orf106 CENPW CYBRD1 DEF6 DNAJB4 EFEMP1 ERGIC3 FOXO3 GIPC2 GNA12 GPR126 GSS HHIP-AS1 HIVEP2 INTS12 ITCH LOC342346 LOXL1-AS1 LRRC29 MAP1LC3A MARCH2 MET MIR3936 NEGR1 NEXN NUCKS1 OTUD4 PABPC4 PDLIM4 PEF1 PIP4K2B PLEKHA1 PPA2 PTCH1 RBBP8 REST RP11-182J1.16 RP11-361D14.2 RP11-435O5.5 RP11-506H20.1 RP3-395M20.9 RPL10A RPS20 SBF2 SH3D21 SHISA4 SLC22A4 SLC22A5 SMPD2 SUOX TBX6 TRMT61B UBA7 ZNF76
Pulse rate, automated reading 1.44 24 14 42.4 0.29 1.5e-01 AC007319.1 ALKBH5 BRWD1-IT2 C6orf106 CALCRL EIF2AK4 FAM171B GAB2 GJA1 GNL3 KIAA1683 MET MUTYH NEGR1 PABPC4 PCGF2 PPP1R3E RP11-351A11.1 RP11-382A20.2 RP11-95P2.1 SBF2 SERPING1 SERTAD2 SUOX
Alcohol intake frequency. 1.00 6 2 6.1 -0.25 6.3e-01 CCDC144B CRHR1 FUT2 LRP1 PPA2 SUOX
Comparative height size at age 10 2.11 84 59 178.8 0.06 5.6e-01 AC010883.5 AC103965.1 ADCY3 ATP6V0D1 BOK BTBD8 C10orf11 C1orf43 C5orf56 C6orf106 C9orf156 CCDC144B CENPW CRHR1 CYBRD1 DEF6 EFEMP1 ERGIC3 EVI5 FARP2 FOXO3 FUT2 GIPC2 GNA12 GOLGA6L4 GOLGA6L5 GPR126 GSS HHIP-AS1 HIVEP2 ITCH KIF1B LIN52 LOXL1-AS1 MAP1LC3A MFAP2 MIR3936 MRPS6 MSL1 MST1L MST1P2 MTMR11 NBPF1 NEXN NUCKS1 OTUD4 PADI2 PDE2A PDLIM4 PIP4K2B PLEKHA1 PPA2 PSTPIP1 PTCH1 RANBP10 RBBP8 RP11-108M9.5 RP11-165J3.6 RP11-182J1.16 RP11-361D14.2 RP11-435O5.5 RP11-506H20.1 RP11-6N17.6 RP11-797A18.4 RP11-810M2.2 RPL10A RPS20 RPS6KL1 SCAND2P SH3D21 SLC22A4 SLC22A5 SMPD2 SOX9 TBX6 TMEM170A TMEM41B TRAF3IP1 UBE2Q2 UBE2Q2P1 UQCRQ ZNF354C ZNF76 ZSCAN2
Number of full sisters 1.28 1 0 0.0 0.00 1.0e+00 NRBF2
Suffer from 'nerves' 0.98 2 0 0.0 0.00 1.0e+00 RPS6KL1 TBX6
Overall health rating 1.15 4 2 6.1 -0.10 9.0e-01 HTR4 LINC00674 TOM1L2 UBA7
Age at last live birth 0.98 1 1 3.0 0.00 1.0e+00 UBA7
Medication: Aspirin 1.04 1 0 0.0 0.00 1.0e+00 CELSR2
Knee pain experienced in last month 1.09 2 0 0.0 0.00 1.0e+00 ERGIC3 PABPC4
Hypertension (Self-reported) 1.46 19 12 36.4 0.45 4.8e-02 ARHGAP42 ATP2B1 C1GALT1 CEP41 DNAJC11 EEFSEC FUT2 GNGT2 HTR4 KB-1107E3.1 MET MIR3936 NRBF2 RP11-810M2.2 RUVBL1 SLC22A5 SUOX TMEM133 VGLL4
Illnesses of father: Heart disease 1.29 3 1 3.0 0.00 1.0e+00 CELSR2 RP11-378J18.8 SMAD3
Forced expiratory volume in 1-second (FEV1), predicted 1.86 28 21 63.6 -0.08 6.4e-01 AC103965.1 ADCY3 C6orf106 CENPW DEF6 ERGIC3 GNA12 GOLGA6L4 GOLGA6L5 GPR126 HHIP-AS1 HIVEP2 LOXL1-AS1 MAP1LC3A MFAP2 MIR3936 MST1L MST1P2 OTUD4 PTCH1 RP11-182J1.16 RP11-361D14.2 RP11-435O5.5 RPL10A SLC22A5 UBE2Q2P1 ZNF76 ZSCAN2
Whole body fat-free mass 1.85 66 52 157.6 -0.17 1.2e-01 ACTR1A ADM AMPD3 ARHGEF26 BTBD8 C10orf11 C16orf93 C5orf56 C6orf106 CENPW CPEB4 CTC-228N24.3 CYBRD1 DEF6 DNAJB4 EFEMP1 EPHA2 ERGIC3 FOXO3 GIPC2 GNA12 GPR126 GSS HHIP-AS1 HIVEP2 INTS12 ITCH LOC342346 LOXL1-AS1 MAP1LC3A MARCH2 MET MIR3936 MSL1 NEGR1 NEXN NUCKS1 OTUD4 PABPC4 PDE2A PDLIM4 PEF1 PIP4K2B PLEKHA1 PPA2 PTCH1 RBBP8 REST RP11-361D14.2 RP11-435O5.5 RP11-506H20.1 RPL10A RPS20 SBF2 SH3D21 SHISA4 SLC22A4 SLC22A5 SMPD2 SNX11 SNX33 SUOX TBX6 UBA7 UQCRQ ZNF76
Leg fat-free mass (right) 1.73 64 49 148.5 -0.12 3.0e-01 ACTR1A ADM ARHGEF26 BTBD8 C10orf11 C16orf93 C5orf56 C5orf63 C6orf106 CENPW CPEB4 CTC-228N24.3 CYBRD1 DEF6 DNAJB4 EFEMP1 EHD4 EPHA2 ERGIC3 FOXO3 GIPC2 GNA12 GPR126 GSS HHIP-AS1 HIVEP2 INTS12 ITCH LOXL1-AS1 MAP1LC3A MIR3936 MSL1 NEGR1 NEXN NUCKS1 OTUD4 PABPC4 PDE2A PDLIM4 PEF1 PIP4K2B PLEKHA1 PPA2 PTCH1 RP11-361D14.2 RP11-435O5.5 RP11-506H20.1 RPL10A RPN1 RPS20 SBF2 SH3D21 SHISA4 SLC22A4 SLC22A5 SMPD2 SMURF2 SNX11 SNX33 SUOX TBX6 UBA7 UQCRQ ZNF76
Arm fat percentage (left) 1.20 28 16 48.5 -0.19 3.4e-01 ADCY3 ADM AFAP1 C16orf93 C6orf106 CCDC171 CENPW CPD DNAJC11 HSPD1 HTR4 IQCH KIAA1683 KLF16 KLHL24 LINC00674 NDUFAF1 NEGR1 NTM OXER1 PABPC4 RP1-18D14.7 SBF2 SHISA4 SSH2 SSR3 TBX6 UBA7
Average weekly red wine intake 1.00 1 0 0.0 0.00 1.0e+00 SERPING1
Handedness (chirality/laterality): Left-handed 0.87 1 1 3.0 0.00 1.0e+00 CRHR1
Mood swings 1.02 5 3 9.1 0.72 1.7e-01 ASCC2 CRHR1 NUCKS1 RPS6KL1 UBA7
Long-standing illness, disability or infirmity 1.19 3 0 0.0 0.00 1.0e+00 CCDC171 EMB NEGR1
Diabetes diagnosed by doctor 1.46 4 1 3.0 0.96 3.5e-02 AC010883.5 CAMK1D CENPW CLPB
Qualifications: nursing, teaching 1.07 2 1 3.0 0.00 1.0e+00 CFH NEGR1
Eye problems/disorders: Cataract 1.03 1 1 3.0 0.00 1.0e+00 SLC24A3
Mouth/teeth dental problems: Mouth ulcers 0.91 1 1 3.0 0.00 1.0e+00 CRHR1
Back pain experienced in last month 1.09 1 0 0.0 0.00 1.0e+00 C6orf106
Mineral and other dietary supplements 1.13 1 0 0.0 0.00 1.0e+00 NRBF2
Asthma (self-reported) 2.71 30 21 63.6 0.73 7.8e-07 AC114730.7 ADAM19 BACH2 C16orf93 C1orf43 C5orf56 DDX5 DMWD EEFSEC GNGT2 HTR4 IL18R1 IL33 IQCH LRP1 MIR3936 MSL1 ORMDL3 PDLIM4 RUVBL1 SLC22A4 SLC22A5 SMAD3 SRGAP2 SUOX THRA TSPAN14 UQCRQ YRDC ZNF76
Medication: Aspirin 1.04 1 0 0.0 0.00 1.0e+00 CELSR2
Medication: Gliclazide 1.21 1 0 0.0 0.00 1.0e+00 EHD4
Smoking status: Current 1.16 1 1 3.0 0.00 1.0e+00 ACTR1A
Forced expiratory volume in 1-second (FEV1), predicted percentage 2.46 32 18 54.5 -0.90 4.2e-14 ADAM19 BCAR1 C10orf11 CAMK1D CDC123 CHRNA5 CRHR1 CTA-85E5.10 EED FAM168A GJA1 GPR126 HHIP-AS1 HTR4 INTS12 LLGL2 MICAL3 NRBF2 NUDT5 OTUD4 PCGF2 RARB RP11-361D14.2 RP11-382A20.2 SLMAP SMPD2 SOGA2 SPINK9 TMEM133 TMEM170A UBA7 VTA1
Whole body water mass 1.85 67 52 157.6 -0.16 1.5e-01 ACTR1A ADM AMPD3 ARHGEF26 BTBD8 C10orf11 C16orf93 C5orf56 C6orf106 CENPW CPEB4 CTC-228N24.3 CYBRD1 DEF6 DNAJB4 EFEMP1 EPHA2 ERGIC3 FOXO3 GIPC2 GNA12 GPR126 GSS HHIP-AS1 HIVEP2 INTS12 ITCH LOC342346 LOXL1-AS1 MAP1LC3A MARCH2 MET MIR3936 MSL1 NEGR1 NEXN NUCKS1 OTUD4 PABPC4 PDE2A PDLIM4 PEF1 PIP4K2B PLEKHA1 PPA2 PTCH1 RBBP8 REST RP11-361D14.2 RP11-435O5.5 RP11-506H20.1 RPL10A RPS20 SBF2 SH3D21 SHISA4 SLC22A4 SLC22A5 SMPD2 SNX11 SNX33 SUOX TBX6 TRMT61B UBA7 UQCRQ ZNF76
Leg predicted mass (right) 1.72 63 49 148.5 -0.13 2.6e-01 ACTR1A ADM ARHGEF26 BTBD8 C10orf11 C16orf93 C5orf56 C5orf63 C6orf106 CENPW CPEB4 CTC-228N24.3 CYBRD1 DEF6 DNAJB4 EHD4 EPHA2 ERGIC3 FOXO3 GIPC2 GNA12 GPR126 GSS HHIP-AS1 HIVEP2 INTS12 ITCH LOXL1-AS1 MAP1LC3A MIR3936 MSL1 NEGR1 NEXN NUCKS1 OTUD4 PABPC4 PDE2A PDLIM4 PEF1 PIP4K2B PLEKHA1 PPA2 PTCH1 RP11-361D14.2 RP11-435O5.5 RP11-506H20.1 RPL10A RPN1 RPS20 SBF2 SH3D21 SHISA4 SLC22A4 SLC22A5 SMPD2 SMURF2 SNX11 SNX33 SUOX TBX6 UBA7 UQCRQ ZNF76
Arm fat mass (left) 1.26 32 22 66.7 -0.37 2.8e-02 ADCY3 ARHGEF26 C16orf93 C6orf106 CCDC171 DNAJB4 DNAJC11 ERGIC3 FOSB FOXO3 GIPC2 GNA12 HSPD1 HTR4 IQCH ITCH KIAA1683 KLF16 KLHL24 LINC00674 NEGR1 NEXN OTUD4 PABPC4 RP11-810M2.2 RP1-18D14.7 RP3-395M20.9 RPL10A SHISA4 SUOX TBX6 UBA7
Number of self-reported non-cancer illnesses 1.36 6 1 3.0 0.95 3.2e-03 GNGT2 IQCH MIR3936 NEGR1 RUVBL1 SLC22A5
Average weekly champagne plus white wine intake 1.04 1 0 0.0 0.00 1.0e+00 CRHR1
Miserableness 1.05 4 2 6.1 0.53 4.7e-01 CRHR1 LOXL1-AS1 MSL1 UBA7
Guilty feelings 1.11 3 1 3.0 0.00 1.0e+00 CRHR1 PTCH1 RPS6KL1
Eye problems/disorders: Glaucoma 1.15 1 1 3.0 0.00 1.0e+00 AFAP1
Medication: Blood pressure 1.33 7 4 12.1 0.56 1.5e-01 ARHGAP42 C1GALT1 CRHR1 NRBF2 PDLIM4 SLC22A5 TMEM133
High cholesterol (Self-reported) 1.20 2 2 6.1 0.00 1.0e+00 CELSR2 FUT2
Medication: Bendroflumethiazide 1.25 3 0 0.0 0.00 1.0e+00 ATP2B1 MIR3936 SLC22A5
Medication: Paracetamol 1.17 3 2 6.1 0.00 1.0e+00 CRHR1 LRP1 UBA7
Medication: Lisinopril 1.10 2 0 0.0 0.00 1.0e+00 NRBF2 XPA
Medication: Atorvastatin 1.21 1 1 3.0 0.00 1.0e+00 CELSR2
Ever smoked 1.08 4 1 3.0 0.32 6.8e-01 ACTR1A REST TOP2B ZFHX3
Basal metabolic rate 1.79 69 53 160.6 -0.18 1.1e-01 ACTR1A ADM ARHGEF26 BOK BTBD8 C10orf11 C16orf93 C5orf56 C6orf106 CENPW CPEB4 CTC-228N24.3 CYBRD1 DEF6 DNAJB4 EFEMP1 EPHA2 ERGIC3 FOXO3 GIPC2 GNA12 GPR126 GSS HHIP-AS1 HIVEP2 INTS12 ITCH LINC00674 LOC342346 LOXL1-AS1 MAP1LC3A MARCH2 MET MIR3936 MSL1 NEGR1 NEXN NUCKS1 OTUD4 PABPC4 PDE2A PDLIM4 PEF1 PIP4K2B PLEKHA1 PPA2 PTCH1 RBBP8 RP11-182J1.16 RP11-361D14.2 RP11-435O5.5 RP11-506H20.1 RP11-95P2.1 RPL10A RPS20 SBF2 SH3D21 SHISA4 SLC22A4 SLC22A5 SMPD2 SNX11 SNX33 SUOX TBX6 TRMT61B UBA7 UQCRQ ZNF76
Leg fat percentage (left) 1.44 36 20 60.6 -0.46 4.0e-03 ADCY3 ADM C6orf106 CALCRL CCDC171 CENPW CTC-228N24.3 DNAJB4 DNAJC11 FOSB FOXO3 GIPC2 GOLGA6L4 GRK5 HTR4 IQCH KIAA1683 LINC00674 LRP1 MLLT10 MUTYH NDUFAF1 NEGR1 NFE2L1 PPP1R3B RP11-165J3.6 RP11-435O5.5 RP11-810M2.2 RP11-95P2.1 RP3-395M20.9 RPS6KL1 SBF2 SHISA4 SSH2 SYNM UBA7
Arm fat-free mass (left) 1.78 60 45 136.4 -0.20 9.3e-02 ACTR1A ADM ARHGEF26 BTBD8 C10orf11 C16orf93 C6orf106 CENPW CPEB4 CYBRD1 DEF6 DNAJB4 EFEMP1 ERGIC3 FOXO3 GIPC2 GNA12 GPR126 GSS HHIP-AS1 HIVEP2 INTS12 ITCH LOC342346 LOXL1-AS1 MAP1LC3A MARCH2 MET MIR3936 NEGR1 NEXN NUCKS1 OTUD4 PABPC4 PDE2A PEF1 PIP4K2B PLEKHA1 PPA2 PTCH1 RBBP8 RP11-361D14.2 RP11-435O5.5 RP11-506H20.1 RP3-395M20.9 RPL10A RPS20 SBF2 SH3D21 SHISA4 SLC22A4 SLC22A5 SMPD2 SNX11 SNX33 SUOX TBX6 TRMT61B UBA7 ZNF76
Number of operations (self-reported) 1.20 3 1 3.0 0.00 1.0e+00 ARL14EP IQCH PPA2
Average weekly beer plus cider intake 1.16 1 0 0.0 0.00 1.0e+00 UBA7
Irritability 1.16 3 1 3.0 0.00 1.0e+00 AC010883.5 CRHR1 FCHO2
Risk taking 1.14 1 0 0.0 0.00 1.0e+00 EMB
Fractured/broken bones in last 5 years 1.13 1 0 0.0 0.00 1.0e+00 FAM3C
Diastolic blood pressure, automated reading 1.55 34 18 54.5 -0.30 7.1e-02 ADM ANKFY1 ARHGAP42 ATP2A3 ATP2B1 C1GALT1 CPEB4 CTD-3195I5.1 EHD4 HAUS4 KLF16 LSMD1 MAPKBP1 MICAL3 MLTK NDUFAF1 NRBF2 PPP1R3B RBM23 RP11-23P13.4 RP11-351A11.1 RP11-800A3.7 RP11-809N8.4 RPAP1 SBF2 SHISA4 SLC22A5 SLC24A3 SLMAP SUOX THSD4 TMEM133 ULK4 ZZEF1
Myopia 1.08 2 0 0.0 0.00 1.0e+00 BMP4 LRP1
Vascular/heart problems diagnosed by doctor 1.43 18 11 33.3 -0.46 5.0e-02 ARHGAP42 ATP2B1 C1GALT1 CEP41 DNAJC11 EEFSEC GNGT2 KB-1107E3.1 MET MIR3936 NRBF2 RP11-810M2.2 RUVBL1 SERTAD2 SLC22A5 TMEM133 TSPY26P VGLL4
Cholesterol lowering medication 1.22 4 3 9.1 0.09 9.1e-01 CELSR2 EPHA2 FUT2 SSH2
Pain experienced in last month 1.19 6 3 9.1 -0.54 2.7e-01 CENPW HNRNPUL1 LRP1 PABPC4 SUOX UBA7
Heart attack/myocardial infarction (self-reported) 1.13 2 1 3.0 0.00 1.0e+00 CELSR2 RP11-378J18.8
Deep venous thrombosis (DVT) (self-reported) 1.20 2 1 3.0 0.00 1.0e+00 ERGIC3 NME7
Heart disease (siblings) 1.18 1 0 0.0 0.00 1.0e+00 RP11-378J18.8
Pack years of smoking 1.26 1 1 3.0 0.00 1.0e+00 CHRNA5
Impedance of whole body 1.55 74 50 151.5 0.08 5.0e-01 AC010883.5 AC103965.1 ACTR1A ADCY3 ADM AMPD3 ARVCF ATP6V0D1 BTBD8 C10orf11 C6orf106 CENPW CEP41 CRHR1 CTC-228N24.3 CYBRD1 EEFSEC EHD4 EP300 ERGIC3 EVI5 FOSB FOXO3 GAB2 GNGT2 GNL3 GOLGA6L4 GOLGA6L5 GPR126 GTF2IRD2 HELLS HSPD1 ITCH KLF16 LIN52 LOC342346 LSM3 MARCH2 MFAP2 MST1L MST1P2 MTMR11 NBPF1 NEGR1 NEXN NFE2L1 NIPSNAP1 NUCKS1 OTUD4 PABPC4 PEAK1 PEF1 PPP1R3B PSTPIP1 PTCH1 RIF1 RP11-182J1.16 RP11-23P13.4 RP11-797A18.4 RP3-395M20.9 RPL10A RPS20 SBF2 SCAND2P SHISA4 SMPD2 SNX33 SUOX TBX6 TMEM170A UBA7 UBE2Q2P1 ZNF354C ZSCAN2
Leg fat mass (left) 1.37 39 27 81.8 -0.47 1.3e-03 ACTR1A ADCY3 ARHGEF26 C16orf93 C6orf106 CCDC171 CPD DNAJB4 DNAJC11 FOSB FOXO3 GIPC2 GOLGA6L4 HTR4 IQCH ITCH KIAA1683 KLF16 KLHL24 LINC00674 MLLT10 NEGR1 NEXN OTUD4 PABPC4 PEF1 PPP1R3B RP11-182J1.16 RP11-810M2.2 RP1-18D14.7 RP11-95P2.1 RP3-395M20.9 RPL10A SHISA4 SUOX TBX6 UBA7 ZSCAN2 ZZEF1
Arm predicted mass (left) 1.77 61 45 136.4 -0.21 7.4e-02 ACTR1A ADM ARHGEF26 BTBD8 C10orf11 C16orf93 C6orf106 CENPW CPEB4 CYBRD1 DEF6 DNAJB4 ERGIC3 FOXO3 GIPC2 GNA12 GPR126 GSS HHIP-AS1 HIVEP2 INTS12 ITCH LOC342346 LOXL1-AS1 MAP1LC3A MARCH2 MET MIR3936 NEGR1 NEXN NUCKS1 OTUD4 PABPC4 PDE2A PDLIM4 PEF1 PIP4K2B PLEKHA1 PPA2 PTCH1 RBBP8 REST RP11-361D14.2 RP11-435O5.5 RP11-506H20.1 RP3-395M20.9 RPL10A RPS20 SBF2 SH3D21 SHISA4 SLC22A4 SLC22A5 SMPD2 SNX11 SNX33 SUOX TBX6 TRMT61B UBA7 ZNF76

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 135 3.87 5.65
GTEx Adipose Visceral Omentum 63 3.09 4.93
GTEx Adrenal Gland 45 3.09 5.25
GTEx Artery Aorta 105 3.53 5.70
GTEx Artery Coronary 43 3.63 5.00
GTEx Artery Tibial 152 4.04 5.58
GTEx Brain Caudate basal ganglia 27 2.93 4.65
GTEx Brain Cerebellar Hemisphere 48 3.22 4.82
GTEx Brain Cerebellum 72 3.63 5.69
GTEx Brain Cortex 34 3.29 5.54
GTEx Brain Frontal Cortex BA9 34 3.68 5.30
GTEx Brain Hippocampus 11 2.10 4.82
GTEx Brain Hypothalamus 21 3.55 5.47
GTEx Brain Nucleus accumbens basal ganglia 28 3.23 5.15
GTEx Brain Putamen basal ganglia 22 3.53 4.87
GTEx Breast Mammary Tissue 53 2.68 4.82
GTEx Breast Mammary Tissue (Male) 29 2.43 4.27
GTEx Breast Mammary Tissue (Female) 43 2.61 4.61
GTEx Cells EBV-transformed lymphocytes 42 2.96 5.05
GTEx Cells Transformed fibroblasts 141 3.36 5.41
GTEx Colon Sigmoid 55 3.76 5.24
GTEx Colon Transverse 59 2.86 4.83
GTEx Esophagus Gastroesophageal Junction 57 3.94 5.73
GTEx Esophagus Mucosa 107 3.22 5.18
GTEx Esophagus Muscularis 110 3.40 5.20
GTEx Heart Atrial Appendage 46 2.91 4.95
GTEx Heart Left Ventricle 46 3.00 4.92
GTEx Liver 21 2.93 4.73
GTEx Lung 126 4.39 5.74
GTEx Muscle Skeletal 97 3.35 5.02
GTEx Nerve Tibial 138 3.19 5.32
GTEx Ovary 41 4.51 6.18
GTEx Pancreas 55 3.37 5.11
GTEx Pituitary 44 3.94 5.39
GTEx Prostate 30 3.60 5.23
GTEx Skin Not Sun Exposed Suprapubic 90 3.66 5.31
GTEx Skin Sun Exposed Lower leg 139 3.82 5.52
GTEx Small Intestine Terminal Ileum 12 2.60 4.66
GTEx Spleen 58 4.11 5.03
GTEx Stomach 57 3.92 5.16
GTEx Testis 115 3.64 5.25
GTEx Thyroid 153 3.83 5.44
GTEx Uterus 16 2.82 4.33
GTEx Vagina 19 2.99 5.35
GTEx Whole Blood 85 4.27 5.91
METSIM Adipose 158 3.43 4.98
NTR Blood 66 2.75 4.90
ROSMAP Brain Pre-frontal Cortex 135 3.08 4.77
YFS Blood 136 2.95 4.52
CommonMind Brain Pre-frontal Cortex 166 3.09 4.83
TCGA Breast Tumor 31 4.05 5.43
TCGA Breast Normal 107 2.54 4.13
TCGA Ovarian Tumor 70 2.39 4.17
TCGA Prostate Tumor 99 2.86 4.88