Hub : Traits :

Blood Eosinophil Count

6014 significantly associated models · 1526 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 1287040 4263997 12 2 2.9e-15 8.2e-15 1.8e-01 97 TNFRSF14 WRAP73
2 1 7288507 10771488 9 6 2.0e-29 3.9e-32 3.8e-03 94 H6PD LZIC PIK3CD RBP7 RP5-1115A15.1 TMEM201
3 1 11032827 12786444 5 2 2.2e-30 3.1e-34 6.4e-06 86 MIIP
4 1 15829187 16844848 2 1 4.9e-09 1.1e-06 5.4e-01 98 ARHGEF19-AS1
5 1 20291950 21805048 2 1 2.1e-07 1.3e-07 3.7e-02 84 KIF17
6 1 22080775 29259314 40 12 6.4e-28 1.7e-23 4.2e-04 88 CEP85 CLIC4 DNAJC8 EYA3 FUCA1 ID3 LUZP1 TCEA3 TCEB3 THEMIS2 ZBTB40 ZDHHC18
7 1 30506995 31928387 1 1 1.0e-08 1.1e-08 6.9e-06 38 LAPTM5
8 1 32795632 34592020 4 1 2.4e-10 4.1e-13 2.5e-04 74 PHC2
9 1 37566653 40170389 4 2 3.4e-13 1.3e-11 1.0e+00 100 AKIRIN1 INPP5B
10 1 41276073 43194594 1 1 1.2e-10 1.9e-33 2.1e-24 28 HIVEP3
11 1 46017836 47573980 3 1 7.3e-11 2.5e-08 1.2e-01 92 RAD54L
12 1 64515379 66797669 4 5 2.9e-23 8.9e-31 1.7e-10 69 JAK1 LEPR LEPROT RAVER2
13 1 91271668 94534354 8 2 6.4e-28 2.0e-26 1.6e-01 98 CDC7 DR1
14 1 100643910 102246949 4 3 2.0e-32 8.3e-37 2.8e-08 81 EXTL2 RP11-421L21.3
15 1 149672809 151929022 27 8 7.9e-52 1.6e-69 NaN NaN ARNT CA14 GOLPH3L MCL1 MRPS21 SCNM1
16 1 154225344 155726290 5 1 5.6e-11 4.6e-09 3.8e-01 98 DCST2
17 1 156948880 158369319 1 1 2.5e-07 6.8e-07 1.0e+00 100 FCRL3
18 1 160452218 161885352 5 1 5.3e-11 2.4e-12 2.6e-06 55 B4GALT3
19 1 166702558 168182443 1 1 6.2e-15 5.9e-16 1.0e+00 100 CD247
20 1 168932500 170514229 2 1 6.0e-08 8.9e-12 3.2e-05 63 C1orf112
21 1 180360900 181760749 2 1 9.5e-09 5.4e-09 1.8e-01 95 RP11-309G3.3
22 1 200014178 201528243 1 1 3.0e-07 1.3e-07 1.2e-05 31 CAMSAP2
23 1 203698379 205241659 2 1 4.7e-09 2.3e-08 1.0e+00 100 PIK3C2B
24 1 206194087 207554840 3 2 1.3e-10 3.9e-13 5.5e-12 10 DYRK3 IKBKE
25 1 212274413 213728049 2 1 7.5e-11 1.3e-11 2.1e-02 88 TATDN3
26 1 220006085 221753645 3 4 2.2e-14 1.6e-16 1.0e+00 100 HLX MARK1 RP11-295M18.6
27 1 223192017 224650947 1 1 2.4e-07 4.6e-06 1.0e+00 100 CAPN2
28 1 228878522 230400531 3 1 4.8e-16 8.0e-15 1.0e+00 100 HMGN2P19
29 2 8126791 9522950 1 1 2.4e-10 6.8e-36 2.9e-28 22 ID2
30 2 24324172 25735072 1 1 5.1e-08 5.7e-07 5.1e-02 85 CENPO
31 2 26883355 28908597 2 1 4.5e-09 2.6e-33 2.3e-32 3 AC074117.10
32 2 29976100 31563885 1 1 4.3e-09 2.0e-09 3.3e-08 15 LCLAT1
33 2 36738571 38156133 1 1 1.3e-10 3.2e-09 5.6e-02 90 CEBPZ
34 2 42753863 44157441 2 2 8.7e-09 5.5e-11 3.6e-09 19 AC010883.5
35 2 60422555 62807954 13 4 5.4e-17 3.8e-17 1.0e+00 100 PUS10 RP11-493E12.2
36 2 64769481 66995349 2 1 2.5e-15 5.2e-18 7.4e-05 79 AC074391.1
37 2 70596291 72348725 4 1 1.7e-12 2.8e-12 5.9e-11 12 NAGK
38 2 73477527 75429228 3 2 3.2e-12 1.2e-12 7.7e-04 78 DGUOK-AS1 LBX2-AS1
39 2 85067830 87126250 8 3 1.4e-10 6.0e-12 1.0e+00 100 GNLY RP11-301O19.1 VAMP8
40 2 95339024 100615241 27 12 4.8e-131 1.5e-118 NaN NaN AC017099.3 ACTR1B ADRA2B ANKRD36 ANKRD36C FAHD2CP ITPRIPL1 LINC00342 LYG1 TMEM127 ZNF514
41 2 101617631 104049356 9 12 3.4e-166 4.7e-272 NaN NaN IL18R1 IL18RAP IL1R1 IL1R2 IL1RL1 IL1RL2 MFSD9
42 2 105665534 107507702 2 1 4.2e-11 1.3e-11 8.2e-04 76 NCK2
43 2 111830273 113298586 1 1 6.9e-08 1.4e-61 2.9e-59 4 ANAPC1
44 2 135972093 137435625 1 1 6.4e-09 2.7e-15 1.0e-08 48 DARS
45 2 147905651 149475737 2 1 6.4e-10 1.2e-11 2.3e-04 71 ACVR2A
46 2 168949234 170419444 1 1 2.0e-08 2.0e-07 1.0e+00 100 NOSTRIN
47 2 181139278 183092956 2 1 2.7e-09 3.3e-10 2.6e-02 87 ITGA4
48 2 187633716 189122229 1 1 8.9e-08 4.1e-07 3.9e-01 97 TFPI
49 2 195903576 197733242 2 1 5.2e-09 2.4e-11 1.1e-05 57 STK17B
50 2 202952678 205434906 3 2 6.1e-13 2.1e-21 6.9e-12 48 CTLA4 NBEAL1
51 2 211541064 214703618 3 2 1.0e-38 5.3e-160 1.2e-121 24 ERBB4 IKZF2
52 2 233227833 234815167 1 1 1.1e-13 6.8e-33 2.2e-24 27 INPP5D
53 2 238178706 239648926 1 1 7.0e-12 7.7e-11 1.5e-01 95 UBE2F
54 2 240849333 243048760 17 13 1.9e-66 8.6e-60 NaN NaN AC005104.3 AC093642.3 AC114730.11 AC114730.7 D2HGDH GPR35 PPP1R7 SEPT2
55 3 2496493 3918983 1 1 4.0e-07 2.6e-46 4.0e-49 -6 CRBN
56 3 11350553 13608348 7 10 1.4e-22 1.3e-38 NaN NaN CAND2 MKRN2 PPARG SYN2 TIMP4 TSEN2
57 3 15873407 17814553 3 1 1.2e-22 9.4e-26 1.3e-04 87 PLCL2
58 3 27058203 28450371 2 1 3.7e-19 2.3e-21 1.7e-04 84 EOMES
59 3 32299549 33884651 3 2 2.4e-13 6.0e-20 3.7e-09 58 CCR4 CRTAP
60 3 41894440 43826355 9 3 7.2e-24 1.6e-41 1.9e-26 38 CCDC13-AS1 SEC22C ZNF662
61 3 45284315 47717626 3 2 1.9e-09 2.3e-14 2.4e-06 62 CXCR6 NBEAL2
62 3 47813588 53860103 65 10 1.4e-29 2.4e-25 NaN NaN ARIH2 FAM212A GPX1 HEMK1 ITIH4-AS1 RAD54L2 RBM6 RP13-131K19.6 SEMA3B-AS1 TCTA
63 3 97758623 99235739 1 1 4.4e-12 6.3e-11 1.8e-03 77 ST3GAL6
64 3 100350244 102243332 10 2 1.7e-22 2.4e-20 7.7e-01 100 FAM55C NXPE3
65 3 111363738 113430299 4 4 1.5e-14 8.5e-35 1.0e-16 55 CD200 CD200R1 GTPBP8 SLC35A5
66 3 118850251 120486383 1 1 1.2e-07 6.7e-07 8.7e-01 100 GSK3B
67 3 121346656 122860765 2 2 1.3e-09 4.0e-12 7.1e-06 58 CSTA RP11-299J3.8
68 3 126603779 129808869 12 12 1.0e-202 0.0e+00 NaN NaN ACAD9 EEFSEC RAB7A RP11-723O4.9 RPL32P3 RPN1 RUVBL1 TPRA1
69 3 141326602 143224385 2 1 8.9e-11 3.2e-13 6.9e-04 78 TRPC1
70 3 148058326 149499021 1 1 6.7e-11 6.7e-13 3.8e-06 59 HLTF
71 3 159421438 160849094 1 1 2.7e-07 1.0e-09 1.4e-08 14 SMC4
72 3 168789705 170491996 7 2 1.2e-22 1.1e-22 1.0e+00 100 GPR160 MYNN
73 3 170624266 172227905 1 1 1.5e-14 1.8e-14 4.3e-02 93 PLD1
74 3 182942402 184607480 2 1 4.1e-14 3.1e-13 1.0e+00 100 ABCC5
75 3 193664025 195106167 2 1 1.3e-10 4.8e-10 6.2e-02 91 FAM43A
76 3 195734915 197161849 4 8 1.5e-15 4.1e-21 NaN NaN CEP19 NRROS PIGX
77 4 2051518 3451960 1 1 2.1e-08 4.1e-12 3.2e-05 64 TNIP2
78 4 6363608 7765495 1 1 5.6e-10 2.9e-09 1.0e+00 100 GRPEL1
79 4 37915462 40274255 12 7 3.5e-171 1.4e-156 NaN NaN AC021860.1 KLHL5 RP11-617D20.1 TLR1 TLR6 TMEM156
80 4 57080198 58531645 3 1 8.0e-14 2.8e-11 1.8e-02 87 REST
81 4 82645452 84733572 8 2 1.8e-82 1.7e-81 1.0e+00 100 THAP9-AS1 TMEM150C
82 4 89335667 90734728 1 1 2.1e-08 6.4e-09 5.5e-03 77 TIGD2
83 4 99296818 100942337 2 1 3.1e-11 9.1e-09 7.2e-07 26 ADH5
84 4 122377715 124935698 3 2 3.3e-25 7.7e-23 4.4e-02 96 KIAA1109 SPATA5
85 4 153256845 154709854 1 1 5.1e-08 1.4e-20 4.6e-15 29 RP11-285C1.2
86 5 6016507 7454862 1 1 2.0e-07 2.1e-08 1.0e+00 100 PAPD7
87 5 9999146 11452037 1 1 4.6e-12 1.9e-23 1.6e-21 9 DAP
88 5 34920257 36938041 5 2 2.0e-17 1.7e-51 2.1e-26 50 IL7R NADKD1
89 5 42795088 44208409 1 1 1.1e-08 1.2e-06 4.7e-02 83 C5orf34
90 5 49462228 50836718 1 1 1.8e-07 4.2e-08 1.0e+00 100 PARP8
91 5 53827696 55223929 1 1 5.9e-08 1.2e-08 7.9e-02 90 CCNO
92 5 71557313 73083183 1 1 5.1e-11 1.0e-11 1.0e+00 100 FCHO2
93 5 97434545 99024399 3 1 1.7e-16 1.1e-17 1.1e-02 91 CTD-2007H13.3
94 5 106500969 108412472 1 1 7.8e-08 6.1e-07 2.1e-04 45 FBXL17
95 5 109381583 111770880 5 5 5.6e-74 3.3e-84 3.0e-02 99 SLC25A46 TSLP WDR36
96 5 126587995 128116643 1 1 2.0e-10 4.4e-10 1.0e+00 100 CTC-228N24.3
97 5 128541597 134175339 30 16 8.1e-254 3.6e-281 NaN NaN AC063976.3 ACSL6 CDC42SE2 CHSY3 GDF9 HSPA4 KIF3A LYRM7 P4HA2-AS1 PDLIM4 RAD50 SKP1 SLC22A5
98 5 140482871 142404354 5 2 2.0e-82 1.3e-78 5.3e-01 100 NDFIP1 SPRY4
99 5 147516165 148894875 1 1 1.2e-60 5.0e-79 2.6e-20 76 ADRB2
100 5 149712217 151158863 1 1 9.5e-08 3.9e-17 2.6e-12 31 TNIP1
101 5 159129977 160547028 1 1 3.9e-09 3.1e-15 4.5e-08 52 SLU7
102 5 171372346 174088123 2 2 3.7e-08 7.2e-09 1.4e-06 31 CPEB4 NEURL1B
103 5 176040488 177426530 3 1 2.0e-23 4.9e-22 1.0e+00 100 RGS14
104 6 202452 1392108 1 2 4.1e-20 4.9e-57 7.9e-35 40 EXOC2
105 6 11310419 12864134 1 1 9.4e-08 4.3e-09 2.4e-09 -3 HIVEP1
106 6 33662667 36975033 14 10 2.4e-22 8.0e-22 NaN NaN ANKS1A MAPK13 PACSIN1 SRPK1 TEAD3 ZNF76
107 6 41005502 43388216 8 7 1.1e-11 5.9e-22 NaN NaN CCND3 GUCA1A MRPS10 PRPH2 TRERF1 UBR2
108 6 87167376 88880701 8 1 1.1e-11 8.3e-13 1.3e-03 80 RP11-393I2.4
109 6 89579638 91704536 3 4 7.2e-55 6.5e-82 6.6e-22 75 BACH2 LYRM2 MDN1
110 6 105941365 107467855 1 1 3.4e-07 3.2e-45 7.5e-43 5 ATG5
111 6 108612536 110843638 8 8 1.9e-13 4.1e-14 1.0e+00 100 CD164 RP11-425D10.10 SESN1 SMPD2 ZBTB24
112 6 134582344 137931117 4 5 1.0e-19 4.3e-85 2.2e-57 33 AHI1 HBS1L PEX7
113 6 149347912 150761928 1 1 9.5e-08 6.6e-11 7.0e-08 32 NUP43
114 6 151030107 152470136 1 1 1.2e-07 1.2e-10 1.8e-04 66 RMND1
115 7 814788 3778937 4 5 6.4e-23 1.8e-21 4.4e-01 99 CARD11 GNA12 INTS1 TTYH3
116 7 22283925 23861625 2 2 3.6e-18 5.8e-33 1.9e-14 59 AK3P3 FAM126A
117 7 25982367 27880888 6 1 9.3e-13 3.6e-13 1.0e+00 100 SKAP2
118 7 36196921 38186423 1 1 1.0e-08 1.4e-33 3.1e-29 14 ELMO1
119 7 43924401 45920582 7 3 3.0e-18 2.6e-18 1.0e+00 100 CCM2 NACAD SNHG15
120 7 75059331 78122616 16 14 1.1e-23 3.2e-60 NaN NaN AC004980.7 AC005077.14 HIP1 HSPB1 POM121C POR RHBDD2 RSBN1L-AS1 TMEM120A ZP3
121 7 90874777 93160671 8 7 6.1e-27 6.7e-56 NaN NaN AC000120.7 AKAP9 CDK6 FAM133B GATAD1 KRIT1 PEX1
122 7 99591418 100979310 1 1 7.4e-10 4.3e-08 7.3e-02 89 GIGYF1
123 7 127878155 129312570 2 1 2.1e-13 6.0e-13 1.0e+00 100 IRF5
124 7 129917130 131315092 1 1 1.5e-07 1.5e-08 2.6e-07 17 RP11-138A9.1
125 7 134081554 136094817 5 2 3.6e-11 1.1e-11 1.3e-04 68 RP11-134L10.1 SLC13A4
126 7 138030784 140449834 3 2 2.1e-11 1.0e-12 8.9e-05 70 PARP12 ZC3HAV1
127 7 147814190 151119265 15 10 1.4e-85 6.6e-83 NaN NaN GIMAP1 GIMAP7 RP4-800G7.2 ZNF425 ZNF783 ZNF786
128 8 19064892 20521138 1 1 3.8e-08 2.9e-09 2.1e-05 49 LPL
129 8 21600469 23633291 3 3 9.6e-24 2.6e-28 1.9e-01 99 PPP3CC TNFRSF10B
130 8 47421087 49584958 6 2 4.3e-16 1.5e-15 1.6e-02 91 MCM4 SPIDR
131 8 60903659 62477554 1 1 2.4e-13 3.3e-30 2.5e-19 38 CHD7
132 8 80174864 82124528 2 1 2.7e-10 5.7e-14 1.2e-11 19 ZBTB10
133 8 95199215 96825195 3 1 1.2e-10 3.2e-11 2.9e-02 89 TP53INP1
134 8 118508942 121136001 3 2 9.7e-11 1.7e-10 2.3e-01 96 NOV SAMD12
135 8 126867367 129812343 2 3 3.0e-13 6.9e-56 5.5e-41 28 FAM84B PVT1
136 8 144438516 146233840 3 2 1.4e-07 1.9e-07 5.1e-02 86 GS1-393G12.12 KIAA1875
137 9 1923359 3353579 1 1 2.5e-07 4.2e-10 4.1e-08 23 VLDLR
138 9 4093295 7345375 12 19 2.9e-158 0.0e+00 NaN NaN ERMP1 GLDC IGHEP2 IL33 JAK2 KIAA1432 KIAA2026 PDCD1LG2 PLGRKT RCL1 RLN2
139 9 34382175 35792423 2 1 2.0e-09 9.4e-10 1.1e-01 93 PIGO
140 9 85657836 87315117 2 1 3.4e-15 3.2e-15 1.0e+00 100 RMI1
141 9 93170435 94885207 3 1 7.6e-35 1.4e-39 1.9e-09 79 AUH
142 9 116849447 118389134 2 2 5.8e-14 2.7e-32 3.7e-14 59 TNFSF15 TNFSF8
143 9 126321003 127872298 2 1 7.4e-11 3.5e-11 1.0e+00 100 PSMB7
144 9 133755528 137631198 10 6 1.0e-27 2.8e-33 7.7e-31 8 BRD3 CACFD1 GBGT1 GFI1B GTF3C4 RAPGEF1
145 9 138403706 140642331 10 2 2.9e-20 1.7e-20 1.0e+00 100 ENTPD2 SEC16A
146 10 98481 1876813 7 2 5.6e-35 3.4e-47 2.6e-11 79 GTPBP4 IDI1
147 10 4999536 7317647 5 4 1.4e-19 3.5e-21 4.7e-05 81 ASB13 FAM208B IL2RA PRKCQ
148 10 24445550 25939515 1 1 1.5e-13 5.9e-15 8.5e-03 89 PRTFDC1
149 10 26033058 27549961 1 2 1.4e-61 3.0e-56 1.0e+00 100 APBB1IP
150 10 28027163 29671014 4 2 3.4e-50 5.3e-50 2.7e-01 99 RP11-351M16.3 WAC-AS1
151 10 34607015 36198981 3 1 7.9e-11 3.8e-11 1.0e+00 100 RP11-297A16.2
152 10 43219070 44601368 1 1 4.7e-08 1.1e-09 5.1e-03 79 RP11-517P14.2
153 10 63870456 65376395 2 2 6.9e-20 7.3e-97 1.4e-86 11 ADO
154 10 69888483 71352551 1 1 5.4e-08 4.3e-07 1.7e-01 93 STOX1
155 10 74714177 76225597 3 1 4.2e-10 1.1e-07 3.7e-01 97 SEC24C
156 10 89164194 91470834 4 4 8.0e-18 7.8e-38 5.1e-13 68 ATAD1 FAS KILLIN PTEN
157 10 93353083 95513408 5 9 6.0e-56 3.3e-52 NaN NaN EIF2S2P3 HHEX KIF11 MARCH5
158 10 98058920 99903704 5 1 6.4e-10 4.7e-10 1.0e+00 100 FRAT1
159 10 103527782 105108455 2 1 2.0e-10 1.5e-10 5.3e-04 71 TRIM8
160 10 110937872 112588355 2 1 1.5e-15 1.1e-14 1.2e-01 96 ADD3
161 10 125936004 127370912 1 1 8.4e-08 2.6e-07 2.7e-01 95 ZRANB1
162 11 198510 1150353 8 11 4.7e-48 1.6e-35 1.0e+00 100 B4GALNT4 IFITM2 PTDSS2 RP11-326C3.15 RP11-326C3.7
163 11 1619859 3776371 4 2 4.3e-14 6.4e-15 5.4e-06 66 C11orf21 NAP1L4
164 11 16343081 18068163 2 1 2.4e-09 2.2e-09 1.0e+00 100 NUCB2
165 11 26818083 28220506 1 1 8.7e-10 2.1e-12 2.7e-04 73 LIN7C
166 11 46723603 48559571 5 1 2.8e-16 4.6e-17 1.0e+00 100 PSMC3
167 11 56306839 58178587 4 3 1.1e-12 7.2e-28 2.9e-17 40 APLNR MED19 SLC43A3
168 11 60173360 62605067 12 3 2.7e-33 6.4e-31 8.6e-01 100 CD5 FADS1 RPLP0P2
169 11 63011204 66963425 42 9 2.7e-52 4.2e-48 1.0e+00 100 EFEMP2 LTBP3 MAP3K11 MUS81 NUDT22 PACS1 PPP1R14B RP11-867G23.2
170 11 75369353 77433527 5 2 2.4e-61 3.9e-94 3.3e-30 69 LRRC32 PRKRIR
171 11 107181776 109054930 7 1 8.9e-35 6.5e-35 1.0e+00 100 ATM
172 11 110472030 112295421 3 2 7.3e-12 2.2e-12 5.4e-03 84 COLCA2 SIK2
173 11 115953897 117853613 6 3 7.8e-20 1.3e-24 1.5e-08 69 PAFAH1B2 SIDT2 ZNF259
174 11 125374128 126914307 8 1 2.8e-17 8.1e-17 1.0e+00 100 FAM118B
175 12 5738318 6956462 3 3 2.2e-20 1.7e-19 1.0e+00 100 LTBR TNFRSF1A
176 12 45455769 47914353 2 1 2.9e-07 7.3e-10 1.9e-08 17 ARID2
177 12 49872443 52120263 4 1 1.4e-09 4.0e-09 8.8e-04 68 SLC11A2
178 12 52369300 53772927 1 1 1.1e-08 2.3e-10 4.4e-03 80 KRT1
179 12 53991321 58303535 13 5 8.7e-34 7.7e-40 2.6e-21 48 AC034102.1 GLS2 LRP1 NFE2
180 12 61957419 63506862 1 1 8.7e-09 7.8e-09 1.0e+00 100 USP15
181 12 89060567 90682621 3 2 1.0e-11 1.0e-11 1.0e+00 100 DUSP6 RP11-981P6.1
182 12 91849109 93464532 2 2 1.7e-09 1.9e-25 2.6e-16 38 BTG1 CLLU1OS
183 12 108841863 114328548 35 24 2.8e-301 0.0e+00 NaN NaN ADAM1A ALDH2 C12orf52 CUX2 DDX54 FAM216A GPN3 MAPKAPK5-AS1 MYO1H PPP1CC PPTC7 RP1-71H24.1 SH2B3 TCHP TCTN1 TMEM116 UNG VPS29
184 12 120324021 124774793 23 8 3.8e-22 4.0e-18 1.0e+00 100 ABCB9 AC084018.1 CDK2AP1 RP11-282O18.3 SBNO1 SETD8 SPPL3
185 12 132613274 133778796 1 1 7.0e-08 5.2e-08 5.5e-02 88 PXMP2
186 13 30616134 32034308 1 1 7.5e-08 1.9e-11 9.9e-11 7 ALOX5AP
187 13 39533590 43594717 10 13 1.7e-36 4.3e-54 NaN NaN AKAP11 COG6 CYCSP34 ELF1 FOXO1 MRPS31 SUGT1L1 TPTE2P5
188 13 49375072 50962458 2 2 2.9e-11 8.1e-19 1.8e-22 -21 EBPL PHF11
189 13 99047988 100903542 3 2 1.9e-31 1.0e-34 4.5e-13 65 TM9SF2 UBAC2
190 13 113970662 115106996 4 3 4.7e-12 6.3e-15 1.4e-01 96 RASA3 UPF3A
191 14 20758949 22163479 1 1 4.4e-08 6.9e-08 2.2e-01 95 METT11D1
192 14 22670975 26218651 7 5 1.9e-17 3.5e-57 4.6e-39 33 AP1G2 RP11-298I3.1 SLC7A8 STXBP6
193 14 34645201 38715739 9 3 8.2e-12 1.6e-25 2.4e-15 42 NFKBIA PSMA6 SLC25A21
194 14 52042229 53430571 1 1 1.8e-08 7.6e-12 4.8e-05 65 PTGDR
195 14 54715845 56575157 6 1 1.2e-22 3.6e-23 1.0e+00 100 RP11-665C16.6
196 14 60017897 61664530 2 1 5.4e-09 3.8e-08 3.1e-01 97 C14orf39
197 14 64275785 66266677 6 2 2.4e-13 1.5e-13 8.1e-01 100 MAX ZBTB1
198 14 72695406 74410663 5 2 1.4e-15 1.2e-10 6.8e-01 100 PSEN1 RP11-109N23.6
199 14 74829160 76813677 2 2 3.3e-15 7.8e-58 1.0e-36 38 ACYP1 FLVCR2
200 14 77043210 78781111 8 1 4.0e-11 3.6e-10 5.7e-01 99 NOXRED1
201 14 92286262 95294286 3 4 5.5e-22 1.0e-47 8.6e-38 22 IFI27L2 PRIMA1 RIN3
202 14 102288663 104892153 12 4 6.2e-11 2.0e-16 1.7e-02 92 ANKRD9 RCOR1 RP11-45P15.4 TRMT61A
203 15 38088200 39556796 1 1 1.7e-07 6.7e-12 8.8e-06 58 RASGRP1
204 15 40123349 44788705 21 10 5.1e-14 1.5e-12 1.0e+00 100 C15orf57 EHD4 LOC729082 NDUFAF1 NUSAP1 OIP5-AS1 SPTBN5 ZSCAN29
205 15 58188859 59850800 2 1 2.3e-08 2.4e-08 1.7e-02 82 ADAM10
206 15 62716641 64579572 2 2 1.8e-08 3.3e-09 1.0e+00 100 LACTB USP3
207 15 64926130 66368503 1 1 7.6e-08 1.5e-06 9.4e-05 34 IGDCC3
208 15 66662107 69244680 8 7 9.0e-26 1.5e-38 1.4e-11 73 CLN6 MAP2K5 PIAS1 RP11-502I4.3 SMAD3
209 15 70475700 71876010 1 1 2.0e-07 5.8e-12 2.6e-06 53 THAP10
210 15 76527630 78073289 3 1 4.8e-09 1.8e-09 3.0e-04 64 TSPAN3
211 15 79427450 80913123 2 1 5.5e-50 3.5e-49 1.7e-02 97 ST20
212 15 84151637 86990983 14 3 1.7e-10 8.9e-15 1.8e-03 84 AC103965.1 AKAP13 RP11-158M2.3
213 15 90192905 92120170 2 2 1.7e-09 2.1e-18 5.7e-06 73 FURIN GABARAPL3
214 16 511080 1976867 2 1 1.5e-12 1.5e-12 1.0e+00 100 CACNA1H
215 16 2191734 3575270 1 1 2.1e-08 2.6e-38 4.7e-32 17 ZG16B
216 16 3714611 5338275 7 1 9.0e-12 7.7e-09 2.7e-01 96 LOC342346
217 16 10157081 12138068 8 11 6.6e-114 8.3e-124 NaN NaN CLEC16A DEXI RMI2 RP11-396B14.2 RP11-876N24.4 RP11-876N24.5
218 16 20109653 21352507 2 1 1.2e-07 1.7e-11 3.0e-05 62 DCUN1D3
219 16 26518263 28154759 5 3 2.7e-33 1.2e-50 4.2e-22 58 IL21R IL4R
220 16 28825605 31833122 44 8 4.1e-34 3.2e-32 1.0e+00 100 AC002310.12 C16orf93 DOC2A HSD3B7 LOC595101 PPP4C RP11-231C14.4 YPEL3
221 16 56330832 58728822 4 5 7.4e-18 1.3e-20 4.0e-08 65 AC009052.12 CCDC102A NLRC5 ZNF319
222 16 66262051 70840490 38 13 1.9e-30 1.5e-27 1.0e+00 100 CIRH1A NFATC3 PDPR PLA2G15 PRMT7 RP11-296I10.3 SLC9A5 WWP2 ZFP90
223 16 77436921 79943873 1 1 2.0e-10 1.0e-11 2.6e-11 4 WWOX
224 16 85026261 86517100 2 1 2.6e-19 9.2e-31 9.0e-29 7 C16orf74
225 16 87834943 89544756 3 2 2.8e-14 2.4e-34 2.9e-20 43 PIEZO1 RNF166
226 17 3587 1336407 2 1 1.1e-07 8.6e-08 7.3e-02 89 VPS53
227 17 2001657 3638037 1 1 3.8e-12 5.2e-14 3.0e-11 22 RAP1GAP2
228 17 3834598 5714962 8 5 4.3e-30 1.5e-43 6.3e-10 80 AC012146.7 ALOX15 KIF1C SLC25A11 ZMYND15
229 17 6397773 9565411 24 9 1.1e-22 1.6e-30 NaN NaN AC113189.5 ACAP1 CLDN7 DLG4 PIK3R6 SOX15 TNFSF13
230 17 17017584 18914778 8 1 8.0e-12 3.8e-12 7.4e-02 93 TOM1L2
231 17 34146026 35595368 2 1 1.3e-09 4.0e-07 8.0e-01 100 ZNHIT3
232 17 37083464 48347817 75 22 2.7e-36 2.6e-44 NaN NaN ACBD4 CRHR1-IT1 DCAKD EFCAB13 GSDMB IFI35 MED24 MPP2 PLCD3 PLEKHM1 PNPO PPP1R1B SMARCE1 THRA UBE2Z ZNF652
233 17 55681549 58837937 6 2 3.5e-14 3.1e-15 9.4e-05 76 RPS6KB1 SUPT4H1
234 17 65123352 66885526 8 2 1.0e-36 6.2e-39 3.9e-02 98 C17orf58 SH3GL1P3
235 17 67467957 68868764 1 1 4.2e-13 9.5e-17 3.9e-05 76 KCNJ2
236 17 73059836 75194387 6 2 1.9e-11 3.5e-12 3.5e-02 91 RHBDF2 WBP2
237 17 80205713 81051007 1 1 7.0e-09 6.5e-16 5.1e-13 20 B3GNTL1
238 18 12090696 13626101 1 1 4.8e-09 3.1e-10 3.4e-05 57 PTPN2
239 18 19692435 21303692 1 1 7.8e-11 1.0e-13 5.9e-05 71 RBBP8
240 18 42966587 44377004 1 1 9.8e-09 1.0e-08 2.1e-02 84 ATP5A1
241 18 47706580 49306115 2 1 2.6e-09 5.2e-10 6.4e-02 91 SMAD4
242 18 51100222 52540420 1 1 7.6e-09 6.7e-09 1.0e+00 100 POLI
243 18 55645543 57113104 1 1 1.5e-11 2.1e-13 1.1e-10 23 MALT1
244 18 60673332 62088914 1 1 3.7e-23 9.6e-30 3.2e-09 73 SERPINB11
245 18 66371289 68204223 1 1 4.3e-17 5.8e-17 1.0e+00 100 DOK6
246 19 260912 1966232 7 6 8.2e-27 7.5e-23 0.0e+00 -24900 CNN2 GPX4 POLR2E
247 19 2058331 4821612 3 2 3.6e-10 2.3e-11 9.1e-03 85 AC005786.7 MAP2K2
248 19 5195917 6609390 4 1 3.9e-08 1.0e-07 1.5e-01 93 VMAC
249 19 7879326 9273800 1 1 2.7e-07 5.8e-07 1.0e+00 100 ZNF414
250 19 10283932 13954633 7 3 1.1e-11 5.4e-11 7.6e-05 64 CARM1 MAST1 ZNF69
251 19 15909516 17624714 4 4 1.6e-14 2.0e-117 2.1e-75 36 C19orf44 CTC-429P9.2 CTC-429P9.3 NWD1
252 19 17695449 20451172 15 4 2.1e-14 9.6e-20 5.7e-02 96 JUND LPAR2 LRRC25
253 19 36282543 38725416 10 1 4.7e-11 2.1e-11 1.2e-02 86 ZNF260
254 19 39135874 41419653 11 7 2.2e-101 4.1e-142 9.8e-02 100 AC005614.5 MAP3K10 PAF1 SAMD4B SELV SUPT5H
255 19 41765229 43637183 3 1 3.7e-14 1.4e-16 5.5e-04 82 CXCL17
256 19 44649590 48684812 16 12 3.1e-32 3.1e-29 NaN NaN AC074212.6 APOC2 CALM3 CCDC9 DMPK DMWD PPP5C PVRL2 SYMPK TOMM40
257 19 48770567 50214653 2 1 8.3e-20 1.5e-17 1.5e-04 80 BAX
258 19 51560467 53017693 2 2 1.8e-11 7.0e-17 2.6e-14 17 FPR2 FPR3
259 20 61795 2296340 4 3 1.7e-08 5.1e-08 8.4e-02 90 NSFL1C RBCK1 SIRPB1
260 20 16854470 18353550 2 1 2.7e-16 4.5e-18 1.2e-03 86 DSTN
261 20 29833609 32140287 5 4 6.1e-12 1.5e-13 3.4e-15 -14 C20orf112 COX4I2 RP5-1085F17.3 TSPY26P
262 20 48435408 51079271 2 2 1.2e-07 5.3e-20 1.6e-14 30 ATP9A PTPN1
263 21 33710324 35336884 4 2 1.4e-20 1.4e-20 1.0e+00 100 IL10RB-AS1 OLIG1
264 21 44392270 46456957 5 8 1.2e-20 1.3e-19 NaN NaN AGPAT3 C21orf2 ICOSLG RRP1B
265 22 16886873 18655860 3 2 2.0e-15 5.9e-16 1.0e+00 100 BID IL17RA
266 22 19262852 20330744 3 1 1.5e-11 8.4e-10 2.7e-01 97 AC006547.14
267 22 21053389 22685340 4 1 2.5e-10 2.9e-09 2.7e-01 97 CCDC116
268 22 23540414 25723300 10 3 2.7e-19 2.3e-32 1.1e-09 74 GGT1 MIF POM121L9P
269 22 29585080 32995751 17 3 1.1e-30 9.4e-30 9.7e-01 100 RNF185 RNF215
270 22 36191428 38292974 6 5 2.4e-27 5.7e-30 3.6e-11 66 C1QTNF6 FOXRED2 IL2RB PVALB TST
271 22 40472399 43615241 27 12 4.8e-34 4.7e-26 NaN NaN ACO2 CSDC2 CYP2D6 DESI1 EP300 NHP2L1 PMM1 POLR3H RP4-756G23.5 SMDT1
272 22 45848271 47450911 2 1 8.2e-12 1.1e-16 1.9e-06 67 PPARA

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Alzheimer’s Disease (in mother) 1.18 1 1 3.0 0.00 1.0e+00 TOMM40
Alzheimer’s Disease (in father) 1.08 1 0 0.0 0.00 1.0e+00 TOMM40
Alzheimer’s Disease (including proxy) 1.38 5 3 9.1 0.43 4.7e-01 AC012146.7 B4GALT3 GIGYF1 INPP5D TOMM40
Crohns Disease (2017) 2.18 39 30 90.9 0.21 1.8e-01 AC010883.5 ACSL6 ADO CAMSAP2 CCDC116 CENPO DAP FADS1 FAM212A GPX1 ICOSLG IGHEP2 IL18R1 IL18RAP IL1RL1 JAK2 KIAA1109 KIF3A LRRC32 LYRM7 NDFIP1 P4HA2-AS1 PDLIM4 POLR2E PPP1R14B PPP1R1B PPP5C PVALB RAD50 RASGRP1 RBM6 RP11-297A16.2 SEC16A SLC22A5 SMAD3 TMEM156 TNFSF15 TNFSF8 TRMT61A
Irritable Bowel Disease (IBD) 2.26 45 35 106.1 -0.03 8.2e-01 AC010883.5 ACSL6 ADO BACH2 CAMSAP2 CCDC116 CENPO DAP GPR35 GPX1 HHEX ICOSLG IGHEP2 IL18R1 IL18RAP IL1R1 IL1RL1 JAK2 KIAA1109 KIF11 LRRC32 LYRM7 MARCH5 NDFIP1 P4HA2-AS1 PDLIM4 POLR2E PPP1R1B PPP5C PRKRIR PTPN2 RAD50 RBM6 RGS14 RMI2 RP11-297A16.2 RP11-493E12.2 RP13-131K19.6 SEC16A SLC22A5 SMAD3 TCTA THRA TNFRSF14 TNFSF15
Ulcerative Colitis (UC) 1.87 24 14 42.4 -0.30 1.3e-01 CAMSAP2 CCDC116 GNA12 GPR35 GPX1 ICOSLG IGHEP2 IL1R1 IRF5 JAK2 KIAA1109 NDUFAF1 PDCD1LG2 PPP1R1B RBM6 RGS14 RP11-493E12.2 RP13-131K19.6 SEC16A TCTA THRA TNFRSF14 TNFSF15 ZFP90
Reaction Time 1.14 5 2 6.1 0.85 7.0e-02 CLDN7 DLG4 MAPKAPK5-AS1 RMI1 SH2B3
Verbal and Numeric Reasoning (VNR) 0.99 5 1 3.0 0.46 4.4e-01 ABCB9 AC034102.1 PLEKHM1 RBM6 WWP2
Breast Cancer 1.06 12 6 18.2 0.31 3.1e-01 AKAP9 CENPO CPEB4 CTC-228N24.3 EFEMP2 MUS81 P4HA2-AS1 PACS1 PLEKHM1 PVT1 RIN3 SLC22A5
Ovarian Cancer 0.99 2 1 3.0 0.00 1.0e+00 PLEKHM1 PNPO
Prostate Cancer 1.46 7 4 12.1 0.56 1.5e-01 EEFSEC IDI1 PVT1 RPN1 RUVBL1 VAMP8 VPS53
Age at First Birth 1.08 1 1 3.0 0.00 1.0e+00 RBM6
Coronary Artery Disease (CAD) 1.45 3 1 3.0 0.00 1.0e+00 NBEAL1 TOM1L2 UBE2Z
Crohns Disease (2012) 1.87 22 13 39.4 -0.40 6.1e-02 ACSL6 ADO CCDC116 FADS1 FAM212A ICOSLG IGHEP2 IL18R1 IL18RAP IL1RL1 LRRC32 NDFIP1 P4HA2-AS1 PDLIM4 PPP1R14B RAD50 RBM6 RP11-297A16.2 SLC22A5 SMAD3 TNFSF15 TNFSF8
Mean Putamen Volume 1.02 1 1 3.0 0.00 1.0e+00 COX4I2
Fasting Glucose 1.08 2 2 6.1 0.00 1.0e+00 FADS1 NOSTRIN
HbA1C 1.07 1 0 0.0 0.00 1.0e+00 B3GNTL1
HDL Cholesterol 1.68 15 11 33.3 0.23 4.0e-01 CCDC116 FADS1 LPL MYO1H PLA2G15 PPP1R1B PRMT7 PSMC3 RBM6 RP11-138A9.1 SBNO1 TOMM40 UNG ZDHHC18 ZNF259
LDL Cholesterol 1.73 7 6 18.2 -0.36 3.4e-01 CACFD1 CARM1 FADS1 PVRL2 SH2B3 TOMM40 ZNF259
Lupus 1.50 6 3 9.1 0.03 9.4e-01 CCDC116 DEXI GSDMB IFITM2 IRF5 ZNF76
Neuroticism 0.97 1 1 3.0 0.00 1.0e+00 PLEKHM1
Primary Biliary Cirrhosis 1.71 11 6 18.2 0.42 1.3e-01 CARM1 DEXI FCRL3 IRF5 LTBR PLCL2 PLEKHM1 PPP1R14B PPP1R1B RMI2 SH2B3
Rheumatoid Arthritis 1.48 2 1 3.0 0.00 1.0e+00 IRF5 SH2B3
Schizophrenia 1.14 10 3 9.1 0.04 9.0e-01 ABCB9 CA14 CYP2D6 ITIH4-AS1 LPAR2 RP11-231C14.4 RP11-282O18.3 RP5-1115A15.1 TOM1L2 VPS29
Triglycerides 2.08 8 5 15.2 -0.57 1.4e-01 AC074117.10 APOC2 FADS1 LPL PAFAH1B2 PVRL2 SIDT2 ZNF259
Type 2 Diabetes (T2D) 1.42 3 3 9.1 0.93 7.9e-03 EIF2S2P3 HHEX KIF11
Ulcerative Colitis 1.77 14 2 6.1 0.40 1.5e-01 CAMSAP2 CCDC116 GPX1 IGHEP2 IL1R1 IRF5 JAK2 PDCD1LG2 PPP1R1B RBM6 RP11-297A16.2 RP13-131K19.6 TNFRSF14 ZFP90
Blood Platelet Count 2.17 179 147 445.5 0.43 7.0e-11 ABCB9 ABCC5 AC000120.7 AC002310.12 AC005077.14 AC006547.14 AC010883.5 AC021860.1 AC074117.10 AC103965.1 AC114730.11 ACSL6 ADAM1A ADD3 ADH5 ADO ANAPC1 ANKRD9 ARNT ATM ATP5A1 B4GALNT4 BAX BRD3 C12orf52 C16orf93 C1QTNF6 CACFD1 CAND2 CCDC116 CD164 CDC7 CDK2AP1 CDK6 CEBPZ CEP19 CEP85 CLIC4 CNN2 COX4I2 CRHR1-IT1 CTLA4 CUX2 CYCSP34 DCAKD DCUN1D3 DESI1 DMPK DOC2A DOK6 DR1 DSTN EFEMP2 ELF1 EOMES ERMP1 FADS1 FAM133B FAM55C FCHO2 FOXO1 GATAD1 GIGYF1 GLS2 GNA12 GPN3 GPX4 GRPEL1 HBS1L HLX IFITM2 IGDCC3 IGHEP2 IRF5 JAK2 KIAA1875 KIF1C KIF3A LACTB LBX2-AS1 LOC342346 LPAR2 LTBP3 LTBR MAP3K11 MARCH5 MAX MCL1 MED24 MIIP MKRN2 MRPS31 MUS81 NBEAL2 NDFIP1 NFE2 NHP2L1 NUCB2 P4HA2-AS1 PACSIN1 PARP12 PDLIM4 PEX7 PHC2 PHF11 PIEZO1 PIK3C2B PLGRKT POLR2E POLR3H POR PPP1CC PPP1R1B PPP4C PPTC7 PRTFDC1 PSMB7 PSMC3 PTEN RAD50 RAVER2 RCL1 RCOR1 REST RIN3 RLN2 RMI1 RMI2 RNF166 RNF215 RP11-158M2.3 RP11-282O18.3 RP11-326C3.15 RP11-425D10.10 RP11-493E12.2 RP11-617D20.1 RP11-665C16.6 RP11-723O4.9 RP11-867G23.2 RP11-981P6.1 RP1-71H24.1 RPLP0P2 RPN1 RUVBL1 SBNO1 SCNM1 SEMA3B-AS1 SETD8 SH2B3 SIK2 SLC11A2 SLC22A5 SMPD2 SNHG15 SPPL3 STXBP6 SUPT4H1 SYN2 TCTN1 TEAD3 THAP9-AS1 THEMIS2 TIMP4 TMEM120A TNFRSF10B TNFRSF1A TOMM40 TPTE2P5 TRIM8 TRMT61A TSEN2 UBE2Z USP15 VLDLR VPS29 ZBTB24 ZDHHC18 ZFP90 ZNF259
Blood Red Count 1.72 113 95 287.9 0.31 2.7e-04 ABCC5 AC000120.7 AC010883.5 AC012146.7 AC021860.1 AC074117.10 AC084018.1 ACBD4 ADAM1A ANAPC1 ATM BACH2 BRD3 C11orf21 C16orf93 CACFD1 CAND2 CCDC102A CD164 CLIC4 CNN2 COLCA2 COX4I2 CPEB4 CRHR1-IT1 CYCSP34 DAP DARS DOC2A DR1 EIF2S2P3 ELF1 FADS1 FAM133B FAM212A FOXO1 FUCA1 GBGT1 GFI1B GLS2 GPN3 GSDMB GUCA1A HBS1L HHEX ID3 IGDCC3 IGHEP2 ITGA4 JAK2 KIF11 KIF17 KILLIN LOC595101 LRRC25 MAP2K2 MAPKAPK5-AS1 MAST1 MAX MCM4 MRPS31 MYNN NDFIP1 NFE2 PIEZO1 PLEKHM1 PNPO POLI PPARG PPP1R1B PPP4C PPP5C PPTC7 PTPN1 RAD54L RBM6 RCL1 RGS14 RLN2 RP11-158M2.3 RP11-231C14.4 RP11-45P15.4 RP11-617D20.1 RPLP0P2 RRP1B SEPT2 SESN1 SH2B3 SLC25A21 SMPD2 SPIDR SRPK1 SUGT1L1 SYMPK SYN2 TCEB3 THAP9-AS1 TMEM116 TMEM150C TOM1L2 TP53INP1 TPTE2P5 TRERF1 TRIM8 TRMT61A TRPC1 TSEN2 TSPAN3 TSPY26P VPS29 WWP2 YPEL3 ZFP90
Blood White Count 3.68 171 141 427.3 0.57 1.8e-18 ABCC5 AC005104.3 AC006547.14 AC010883.5 AC012146.7 AC021860.1 AC074391.1 AC084018.1 ACAD9 ACSL6 ADAM1A ADD3 ADRB2 AHI1 AK3P3 ALDH2 ALOX15 APBB1IP ARNT ATM ATP5A1 AUH B4GALNT4 B4GALT3 BACH2 BAX BID C11orf21 C12orf52 C16orf93 C19orf44 C5orf34 CA14 CACFD1 CACNA1H CARM1 CCDC116 CCDC9 CD164 CDK6 CENPO CEP19 CHD7 CUX2 CXCL17 CYP2D6 DOC2A DOK6 EFEMP2 ENTPD2 EOMES FADS1 FAM133B FAM84B FRAT1 GATAD1 GBGT1 GGT1 GNA12 GSK3B HBS1L HLTF IFI35 IFITM2 IKZF2 IL17RA IL1R2 KIF3A KRIT1 LAPTM5 LEPR LOC342346 LOC595101 LOC729082 LUZP1 MAPKAPK5-AS1 MAX MCL1 MED24 MIF MKRN2 MPP2 MRPS21 MUS81 NDFIP1 NFKBIA NLRC5 NOSTRIN NOXRED1 P4HA2-AS1 PACSIN1 PARP12 PDLIM4 PDPR PEX1 PEX7 PHF11 PIGX PIK3CD POLI POLR2E POM121C POM121L9P PPP1R1B PPTC7 PRPH2 PRTFDC1 PSMB7 PSMC3 PTDSS2 PVRL2 PVT1 RAB7A RAD50 RBBP8 RBM6 REST RGS14 RIN3 RMI1 RNF185 RP11-138A9.1 RP11-296I10.3 RP11-393I2.4 RP11-45P15.4 RP11-493E12.2 RP11-617D20.1 RP11-665C16.6 RP11-876N24.4 RP11-876N24.5 RP1-71H24.1 RP5-1115A15.1 RPLP0P2 RPN1 SBNO1 SEC16A SH2B3 SLC11A2 SLC22A5 SMPD2 SNHG15 SPPL3 STXBP6 TCEA3 TCTN1 TFPI THAP9-AS1 THEMIS2 THRA TIMP4 TMEM116 TMEM150C TNFRSF10B TNFRSF1A TOM1L2 TRERF1 TRPC1 TSPAN3 UBE2F UNG VLDLR VPS29 WAC-AS1 WBP2 ZBTB24 ZNF662 ZNF69 ZNF76 ZNF783 ZNF786 ZRANB1
Heel T-Score 1.15 83 64 193.9 0.22 3.7e-02 ABCB9 AC000120.7 AC010883.5 AC034102.1 ACO2 ADRA2B AKAP11 AKAP9 APLNR ARHGEF19-AS1 ARIH2 BTG1 C16orf93 CACFD1 CAMSAP2 CCDC116 CCNO CD164 CDK2AP1 CDK6 CEBPZ CLDN7 COX4I2 CPEB4 CRHR1-IT1 CSDC2 CTC-228N24.3 DCAKD EP300 ERMP1 FADS1 FAHD2CP FAM133B FAM212A FCHO2 GATAD1 GNA12 GS1-393G12.12 HLX HSPA4 ID3 IFI35 IGDCC3 IRF5 ITGA4 KRIT1 LCLAT1 LOC595101 LRRC25 MAP2K2 MAP3K11 NHP2L1 PACS1 PLEKHM1 POLR2E POLR3H PPP1R14B PSMA6 PSMB7 RBM6 REST RIN3 RMI1 RP11-231C14.4 RP11-282O18.3 RP11-45P15.4 RP13-131K19.6 RP4-800G7.2 RP5-1115A15.1 RPN1 SETD8 SLC11A2 SLC9A5 STOX1 TCTA TFPI TLR1 TRMT61A TRPC1 USP3 ZBTB1 ZDHHC18 ZNF76
BMI 1.18 62 44 133.3 -0.07 5.7e-01 AC006547.14 AC034102.1 ACTR1B ADAM10 ANKS1A C16orf93 C17orf58 CAND2 CENPO CIRH1A CPEB4 CXCL17 DOC2A EFEMP2 FRAT1 GPN3 GPX1 HHEX HSD3B7 ITGA4 ITIH4-AS1 LIN7C LOC595101 LOC729082 LRP1 MAP2K2 MAP2K5 MED24 MUS81 NDUFAF1 PACS1 PACSIN1 PDPR PHC2 PNPO POM121C PPP4C PPTC7 PSMB7 RBM6 RP11-231C14.4 RP11-296I10.3 RP11-981P6.1 RPN1 RSBN1L-AS1 SH3GL1P3 SMAD3 TEAD3 TFPI THRA TNFRSF14 TNIP2 TRIM8 TRMT61A TSPY26P UBE2Z UBR2 USP3 VPS29 WBP2 WWP2 ZNHIT3
Height 1.46 186 156 472.7 -0.31 6.2e-06 ABCB9 AC000120.7 AC005104.3 AC010883.5 AC021860.1 AC063976.3 AC074391.1 AC103965.1 AC113189.5 ACAP1 ACBD4 ACSL6 ADO AK3P3 AKAP13 AKAP9 ANKRD36 ANKS1A APOC2 ARHGEF19-AS1 ARIH2 ATP9A BRD3 C14orf39 C17orf58 CA14 CACFD1 CACNA1H CAND2 CARM1 CCDC116 CCDC9 CCNO CCR4 CD164 CDC42SE2 CDC7 CDK2AP1 CDK6 CENPO CEP85 COG6 COX4I2 CRTAP CTC-228N24.3 CXCL17 DAP DCAKD DESI1 DGUOK-AS1 DOC2A DSTN EBPL EFCAB13 ELF1 FADS1 FAM133B FOXRED2 GATAD1 GGT1 GIGYF1 GLS2 GNA12 GRPEL1 HEMK1 HIVEP3 IFI35 IL18R1 IL18RAP IL1R1 IL1RL1 IL7R IRF5 ITIH4-AS1 KCNJ2 KIF17 KIF3A KRIT1 LBX2-AS1 LOC729082 LPAR2 LPL LRP1 LUZP1 LYRM7 MAP2K2 MAP3K10 MAP3K11 MAPK13 MARCH5 MARK1 MAX MED24 MKRN2 MRPS21 MRPS31 MUS81 NDUFAF1 NFKBIA NOSTRIN NUCB2 NUSAP1 OIP5-AS1 P4HA2-AS1 PACSIN1 PAPD7 PARP12 PDLIM4 PDPR PEX1 PHC2 PIEZO1 PLCD3 PLEKHM1 POLR2E POM121C PPARA PPP4C PPTC7 PRTFDC1 PSMC3 PTDSS2 PTEN PUS10 PVT1 RAD50 RBBP8 RBCK1 REST RGS14 RMI1 RMND1 RP11-231C14.4 RP11-282O18.3 RP11-295M18.6 RP11-296I10.3 RP11-351M16.3 RP11-425D10.10 RP11-517P14.2 RP11-617D20.1 RP13-131K19.6 RP4-800G7.2 RP5-1085F17.3 RP5-1115A15.1 RSBN1L-AS1 SBNO1 SEC16A SEMA3B-AS1 SEPT2 SESN1 SETD8 SH2B3 SH3GL1P3 SLC11A2 SLC13A4 SLC22A5 SMPD2 SOX15 SPPL3 SRPK1 STOX1 SUGT1L1 TCTA TEAD3 THRA TLR1 TNFSF13 TOM1L2 TRMT61A TRPC1 TSEN2 TSPAN3 UBE2Z UPF3A USP3 WAC-AS1 WWP2 ZBTB24 ZDHHC18 ZNF260 ZNF414 ZNF652 ZNF76 ZNF783 ZNF786 ZRANB1
Waist Hip Ratio (WHR) 1.34 40 29 87.9 0.11 4.7e-01 ABCB9 ADAM10 AUH BRD3 CAND2 CPEB4 CRHR1-IT1 CTC-228N24.3 EIF2S2P3 FAM212A GPX1 IFI35 JUND KCNJ2 LRRC25 LUZP1 MAP3K10 MAP3K11 MARK1 MKRN2 PHF11 PLEKHM1 PSMC3 RNF215 RP11-138A9.1 RP11-282O18.3 RP11-876N24.5 RP13-131K19.6 RSBN1L-AS1 SETD8 SMAD3 SYN2 TCEA3 TCTA TFPI TIMP4 TOM1L2 TSEN2 USP3 ZFP90
Systolic Blood Pressure 1.42 80 55 166.7 0.38 3.3e-04 ABCC5 AC006547.14 AC010883.5 AC074212.6 AC113189.5 ACAP1 ACBD4 ADAM1A ADO ADRB2 C15orf57 CDK6 CENPO CLDN7 CLIC4 CPEB4 CTC-228N24.3 DCAKD DCUN1D3 DLG4 DMPK DOC2A FAM133B GATAD1 GIMAP7 GPN3 HHEX ITGA4 ITIH4-AS1 KIF11 LIN7C LOC342346 MAP3K11 MAPKAPK5-AS1 MARK1 MED19 MIIP MUS81 MYNN NDUFAF1 NFKBIA NUCB2 OIP5-AS1 PLCD3 PLEKHM1 PPTC7 PSMB7 PSMC3 RCOR1 RIN3 RP11-138A9.1 RP11-158M2.3 RP11-296I10.3 RP11-297A16.2 RP11-298I3.1 RP11-981P6.1 RP5-1115A15.1 RRP1B SEC24C SH2B3 SH3GL1P3 SIK2 SLC13A4 SMAD3 SMC4 SPRY4 SPTBN5 TCEB3 TCHP TEAD3 THAP9-AS1 TMEM116 TOM1L2 TP53INP1 TRIM8 UBE2Z UPF3A VPS29 WBP2 ZDHHC18
Smoking Status 1.10 7 5 15.2 -0.22 5.9e-01 AC034102.1 DESI1 LIN7C PHC2 PPP1R14B RP5-1115A15.1 SEMA3B-AS1
Allergy or Eczema 4.15 96 67 203.0 0.88 8.4e-38 ABCB9 AC010883.5 AC034102.1 AC093642.3 AC114730.7 ACO2 AHI1 ATP9A B4GALT3 BACH2 CARD11 CCDC116 CCR4 CD247 CDK2AP1 CEP19 CLEC16A CLIC4 D2HGDH DESI1 DEXI EFEMP2 EP300 ERMP1 FAM55C FOXO1 GLDC GLS2 IFITM2 IGHEP2 IL18R1 IL18RAP IL1R1 IL1R2 IL1RL2 IL2RA IL4R IL7R JAK2 KIAA1109 KIAA1432 KIF3A LCLAT1 LOC729082 LRP1 LRRC32 MAP3K11 MED24 MUS81 NADKD1 NDFIP1 NDUFAF1 NHP2L1 NRROS NUSAP1 OIP5-AS1 P4HA2-AS1 PACS1 PACSIN1 PIGX PLGRKT POLI POLR3H PPP1R1B PRKCQ PRKRIR PSMB7 PVRL2 RGS14 RP11-282O18.3 RP11-396B14.2 RP11-493E12.2 RP11-502I4.3 RP11-876N24.4 RP11-876N24.5 RP4-756G23.5 RP5-1115A15.1 SESN1 SETD8 SIK2 SLC22A5 SLC25A46 SMAD3 SMAD4 SMARCE1 SPATA5 SPPL3 THRA TMEM201 TNFRSF14 TOM1L2 TSLP WDR36 ZFP90 ZNF425 ZNHIT3
Cardiovascular Disease 1.45 47 23 69.7 0.45 1.4e-03 AC006547.14 AC010883.5 AC113189.5 ADO ADRB2 C16orf93 CARM1 CDK6 COX4I2 CPEB4 DCAKD DLG4 GATAD1 HSD3B7 LOC729082 LPL MAPKAPK5-AS1 NDUFAF1 NFKBIA NUCB2 NUSAP1 OIP5-AS1 PNPO PSMC3 PVRL2 RAD50 RP11-138A9.1 RP11-981P6.1 RP5-1115A15.1 RRP1B SH2B3 SIK2 SMARCE1 SPRY4 SPTBN5 TCHP TMEM116 TOMM40 TP53INP1 TRMT61A TSPY26P UBE2Z UPF3A WBP2 ZDHHC18 ZNF259 ZNF652
Hypothyroidism (self reported) 2.41 45 35 106.1 0.49 2.0e-04 AC005104.3 AC034102.1 AC114730.7 ACO2 ADAM1A AKAP11 ALDH2 ANKRD36 ASB13 BACH2 C12orf52 C1QTNF6 CD247 CHD7 CTLA4 CUX2 DOK6 EFCAB13 FADS1 FCHO2 FCRL3 GIGYF1 IRF5 JUND LRRC25 MAPKAPK5-AS1 MYNN POLR3H PPP1R14B PSMB7 PTPN2 PVT1 RASGRP1 RAVER2 RP11-617D20.1 RP5-1115A15.1 SEPT2 SESN1 SH2B3 SYN2 TCEB3 TCHP TCTN1 TIMP4 VPS29
Respiratory disease 4.05 62 50 151.5 0.89 1.7e-28 AC034102.1 AC093642.3 AC114730.11 AC114730.7 ACO2 ACSL6 AHI1 BACH2 CD247 CLEC16A D2HGDH DESI1 DEXI EIF2S2P3 ERMP1 FADS1 FOXO1 GLDC HHEX IL18R1 IL1R1 IL1RL2 IL33 IL4R KIAA1109 KIAA1432 KIF11 KIF3A LOC729082 LRP1 LRRC32 MARCH5 MED24 NBEAL1 NDFIP1 NHP2L1 NRROS NUSAP1 P4HA2-AS1 PDLIM4 POLR3H PPP1R1B PRKCQ PRKRIR RAD50 RP11-396B14.2 RP11-876N24.4 RP11-876N24.5 RP5-1115A15.1 SEC24C SIK2 SLC22A5 SLC25A46 SMAD3 SPATA5 SPPL3 THRA TSLP UBAC2 WDR36 ZNF652 ZNF76
Type 2 Diabetes (T2D) 1.38 8 5 15.2 -0.26 4.5e-01 AC010883.5 EIF2S2P3 FAM212A HHEX KIF11 RBM6 RP11-138A9.1 WWP2
Lung FEV1/FVC ratio 1.45 74 45 136.4 -0.24 3.8e-02 AC005104.3 AC010883.5 AC034102.1 AC074212.6 AC103965.1 ACO2 ADD3 BACH2 C16orf93 C17orf58 C20orf112 CCDC102A CCDC9 CD164 CENPO CLDN7 COG6 CPEB4 CTC-228N24.3 CTD-2007H13.3 CTLA4 D2HGDH DEXI DMPK EBPL EEFSEC EHD4 FAM55C FOXO1 GLDC GNA12 GPX1 IFITM2 IL18R1 IL1RL2 IL33 JUND LOC342346 LOC595101 LRP1 LRRC25 LTBR LYG1 MAP3K10 MARK1 MUS81 NDUFAF1 NFKBIA P4HA2-AS1 RAB7A RGS14 RP11-298I3.1 RP11-396B14.2 RP11-493E12.2 RPN1 RUVBL1 SEC24C SEPT2 SESN1 SH3GL1P3 SLC22A5 SMAD3 SPTBN5 SYMPK TCEA3 TIGD2 TNFSF13 TOM1L2 TPRA1 TSPAN3 TSPY26P ZNF319 ZNF652 ZNF76
Lung FVC 1.16 55 39 118.2 0.21 1.0e-01 ABCB9 AC034102.1 AC113189.5 ACSL6 ARHGEF19-AS1 ARNT C5orf34 CA14 CACFD1 CALM3 CDK2AP1 CLDN7 COX4I2 CRHR1-IT1 CTC-228N24.3 DARS DLG4 GS1-393G12.12 HEMK1 HLX JUND LIN7C LRRC25 MAPK13 MARK1 MCL1 MRPS21 P4HA2-AS1 PACS1 PDLIM4 PDPR PIEZO1 PLEKHM1 PPP1R1B RIN3 RNF185 RP11-282O18.3 RP11-296I10.3 RP11-425D10.10 RP11-493E12.2 RPLP0P2 SCNM1 SEC16A SKAP2 SLC22A5 SMPD2 SOX15 SPPL3 SRPK1 TCHP TEAD3 TSEN2 VMAC WWP2 ZNF76
Neuroticism 1.10 11 4 12.1 -0.04 9.1e-01 ACO2 EP300 MYO1H PLCL2 PLEKHM1 POR RNF166 RP5-1115A15.1 SYN2 TCEA3 THRA
Chronotype (morning person) 1.07 9 1 3.0 0.40 2.8e-01 CXCL17 DESI1 GLS2 MAPKAPK5-AS1 MRPS21 PSMB7 RMI1 SEC16A SYN2
Hair Pigment 0.34 32 23 69.7 0.10 5.8e-01 ABCB9 AC006547.14 AC010883.5 ACO2 ADD3 ARID2 B3GNTL1 C14orf39 C20orf112 CDK2AP1 DUSP6 EOMES ERMP1 EXOC2 GIGYF1 KIAA1432 MAPKAPK5-AS1 MKRN2 PIEZO1 PNPO RNF166 RP11-282O18.3 RP11-297A16.2 RP11-299J3.8 RP11-981P6.1 RP5-1085F17.3 SETD8 SH2B3 TRMT61A TSEN2 TSPY26P ZNF76
Tanning 0.31 9 6 18.2 0.09 7.8e-01 ARNT EXOC2 GOLPH3L MAPK13 PIEZO1 RNF166 SH2B3 ST3GAL6 TSPY26P
Hand grip strength (left) 1.15 13 10 30.3 0.76 2.7e-03 CENPO DOC2A P4HA2-AS1 PDLIM4 PDPR PHC2 PLEKHM1 PPP4C RP11-296I10.3 SLC22A5 WWP2 ZNF260 ZNF76
Number of treatments/medications taken 1.31 4 3 9.1 -0.61 3.9e-01 LRP1 RBM6 SH2B3 SH3GL1P3
Sensitivity / hurt feelings 1.02 2 2 6.1 0.00 1.0e+00 MYO1H PLEKHM1
Frequency of depressed mood in last 2 weeks 0.99 1 0 0.0 0.00 1.0e+00 RP5-1115A15.1
Hearing difficulty/problems: Yes 1.06 2 1 3.0 0.00 1.0e+00 CLDN7 UNG
Relative age of first facial hair 1.00 6 1 3.0 0.23 6.6e-01 CTLA4 KILLIN PLEKHM1 RAD54L2 SPPL3 USP3
Ever used hormone-replacement therapy (HRT) 1.00 1 0 0.0 0.00 1.0e+00 PSMB7
Systolic blood pressure, automated reading 1.25 28 14 42.4 -0.43 2.2e-02 AC006547.14 ACBD4 ADRB2 CDK6 CLDN7 CPEB4 DCAKD DLG4 DMPK FAM133B GATAD1 HSD3B7 MAPKAPK5-AS1 MED19 NDUFAF1 NFKBIA OIP5-AS1 PLEKHM1 PSMB7 RP11-298I3.1 RP11-981P6.1 RP5-1115A15.1 SEC24C SH2B3 SMC4 TEAD3 TMEM116 UPF3A
Vitamin and mineral supplements 1.11 2 1 3.0 0.00 1.0e+00 LRP1 RP11-665C16.6
Medication: Metformin 1.24 4 2 6.1 -0.19 7.2e-01 AC010883.5 EIF2S2P3 HHEX KIF11
Diabetes (father) 1.21 2 2 6.1 0.00 1.0e+00 AC010883.5 EIF2S2P3
Diabetes (mother) 1.24 3 3 9.1 -0.25 7.5e-01 EIF2S2P3 NFATC3 PLA2G15
Impedance of leg (right) 1.29 53 33 100.0 -0.27 4.8e-02 AC005104.3 AC006547.14 AC010883.5 AC034102.1 AC074117.10 AC103965.1 ACBD4 ARID2 ARNT C14orf39 CDC42SE2 CTC-228N24.3 DCAKD DCST2 DOC2A EFEMP2 EP300 ERMP1 GIMAP7 GS1-393G12.12 HEMK1 HSD3B7 ITIH4-AS1 JUND LIN7C LOC595101 LPAR2 LRRC25 MARK1 MCL1 MUS81 PACSIN1 PARP12 PDPR PHC2 PLA2G15 POM121C PPP4C RBM6 RIN3 RP11-231C14.4 RP11-393I2.4 RP11-425D10.10 SCNM1 SEMA3B-AS1 TEAD3 TOM1L2 TRIM8 TSPAN3 USP3 ZBTB24 ZC3HAV1 ZNF652
Leg fat-free mass (left) 1.45 61 46 139.4 0.53 1.7e-06 ABCB9 AC005104.3 AC006547.14 AC034102.1 AC074117.10 ACBD4 ARHGEF19-AS1 ARID2 C14orf39 C16orf93 CD164 CDC42SE2 CDK2AP1 CDK6 CEP85 CPEB4 CRTAP CTC-228N24.3 DCST2 DOC2A EFEMP2 FAM133B GATAD1 GNA12 GPN3 HIVEP3 HSD3B7 KRIT1 LIN7C LOC595101 MRPS31 NFKBIA NOSTRIN P4HA2-AS1 PACSIN1 PARP12 PDLIM4 PHC2 PLCD3 PPP4C PPTC7 RBM6 RIN3 RMND1 RP11-231C14.4 RP11-282O18.3 RP11-425D10.10 RPN1 RSBN1L-AS1 SEPT2 SETD8 SH2B3 SH3GL1P3 SLC22A5 SMPD2 TEAD3 TRIM8 UPF3A VPS29 ZBTB24 ZRANB1
Trunk fat percentage 1.24 44 33 100.0 -0.37 1.1e-02 AC103965.1 ACO2 ARIH2 C16orf93 C17orf58 CENPO DCAKD DESI1 DOC2A FAM212A HSD3B7 JUND LIN7C LOC595101 LOC729082 LRRC25 MAP2K2 MAP2K5 MAPK13 NDUFAF1 PACS1 PACSIN1 PDPR PLEKHM1 PMM1 POLR3H POM121C PPARG PPP4C RBM6 RIN3 RP11-138A9.1 RP11-231C14.4 RP11-296I10.3 RP11-981P6.1 RP5-1115A15.1 RSBN1L-AS1 SH3GL1P3 SMAD3 TEAD3 TIMP4 UPF3A WBP2 WWP2
Hand grip strength (right) 1.20 13 8 24.2 0.78 6.2e-04 ACBD4 BRD3 CENPO DOC2A MAX P4HA2-AS1 PDLIM4 PDPR PLEKHM1 PPP4C RP11-296I10.3 SLC22A5 ZNF260
Current tobacco smoking 1.16 3 2 6.1 0.66 2.3e-01 ACO2 DESI1 POLR3H
Maternal smoking around birth 1.13 2 0 0.0 0.00 1.0e+00 ACO2 PMM1
Fed-up feelings 1.14 5 3 9.1 0.59 3.0e-01 GPX1 PLEKHM1 PPP1R14B RBM6 SH2B3
Relative age voice broke 1.07 1 1 3.0 0.00 1.0e+00 PLEKHM1
Taking other prescription medications 1.54 5 2 6.1 -0.78 1.2e-01 D2HGDH PPP1R1B RBM6 SH2B3 SH3GL1P3
Age when periods started (menarche) 1.18 13 6 18.2 0.09 7.6e-01 CENPO COG6 DOC2A EEFSEC GPX1 HEMK1 NFKBIA PDPR RMND1 RP11-231C14.4 RP11-296I10.3 RP11-493E12.2 WWP2
Heel bone mineral density (BMD) T-score, automated (left) 1.16 10 8 24.2 -0.08 8.2e-01 AKAP11 CDK6 CEBPZ EP300 FADS1 FAM212A RBM6 RP5-1115A15.1 SLC9A5 TRMT61A
High blood pressure 1.31 21 8 24.2 -0.73 1.5e-04 ADRB2 C16orf93 DLG4 DOC2A HSD3B7 MAPKAPK5-AS1 P4HA2-AS1 PDLIM4 PSMC3 RP11-138A9.1 RP5-1115A15.1 RRP1B SH2B3 SIK2 SLC22A5 TMEM116 TRMT61A TSPY26P UBE2Z WBP2 ZDHHC18
Hayfever, allergic rhinitis or eczema 3.79 69 46 139.4 -0.87 1.3e-25 AC034102.1 AC093642.3 AC114730.7 ACO2 B4GALT3 BACH2 CARD11 CCDC116 CCR4 CD247 CEP85 CLEC16A CLIC4 D2HGDH DESI1 DEXI EFEMP2 ERMP1 FOXO1 GLDC GLS2 GSDMB IL18R1 IL1R1 IL1RL2 IL2RA IL4R IL7R KIAA1109 KIF3A LCLAT1 LOC729082 LRP1 LRRC32 MED24 MUS81 NDFIP1 NDUFAF1 NUSAP1 P4HA2-AS1 PACS1 PIGX PLGRKT POLI POLR3H PPP1R1B PRKCQ PRKRIR PSMB7 PVRL2 RAD50 RGS14 RP11-282O18.3 RP11-396B14.2 RP11-493E12.2 RP11-876N24.4 RP11-876N24.5 RP5-1115A15.1 SIK2 SLC22A5 SLC25A46 SMAD3 SMAD4 SMARCE1 SPATA5 SPPL3 THRA TSLP WDR36
Medication: Atenolol 1.26 1 1 3.0 0.00 1.0e+00 SH2B3
Medication: Levothyroxine sodium 2.04 21 13 39.4 -0.59 3.3e-03 AC005104.3 AC034102.1 ADAM1A ASB13 BACH2 CTLA4 DOK6 EFCAB13 FADS1 LRRC25 MAPKAPK5-AS1 MYNN PPP1R14B RASGRP1 SEPT2 SH2B3 SYN2 TCTN1 TIMP4 TMEM116 VPS29
Sitting height 1.41 81 61 184.8 0.43 2.4e-05 ABCB9 AC103965.1 ACBD4 AKAP13 ARID2 ARIH2 ATP9A BRD3 C14orf39 CACFD1 CCDC116 CCNO CCR4 CD164 CDK2AP1 CDK6 CENPO CEP85 CHSY3 COX4I2 CRTAP CXCL17 DCAKD EBPL FAM133B GATAD1 GIGYF1 GNA12 IFI35 KIF17 KRIT1 LPAR2 LRP1 MAX NOSTRIN NOV NUSAP1 OIP5-AS1 P4HA2-AS1 PACSIN1 PARP12 PDLIM4 PDPR PLCD3 PLEKHM1 PPARA PRTFDC1 PSMC3 PUS10 REST RGS14 RP11-282O18.3 RP11-296I10.3 RP11-425D10.10 RP13-131K19.6 RSBN1L-AS1 SBNO1 SEC16A SETD8 SLC11A2 SLC13A4 SLC22A5 SLC9A5 SMPD2 SOX15 SRPK1 STOX1 TCTA TEAD3 TFPI TRPC1 UBE2Z UPF3A USP3 WAC-AS1 WWP2 ZBTB24 ZNF414 ZNF76 ZNF783 ZRANB1
High blood pressure (mother) 1.11 1 0 0.0 0.00 1.0e+00 UBE2Z
Body mass index (BMI) 1.19 41 25 75.8 0.11 4.8e-01 AC006547.14 AC034102.1 C16orf93 C17orf58 CENPO CXCL17 DARS DOC2A EFEMP2 GPN3 GPX1 HSD3B7 ITIH4-AS1 LIN7C LOC595101 MAP2K2 MAP2K5 MUS81 PACS1 PACSIN1 PDPR PHC2 PNPO POM121C PPP4C PPTC7 RBM6 RP11-231C14.4 RP11-296I10.3 RP11-981P6.1 RP5-1115A15.1 SH3GL1P3 SMAD3 TEAD3 TFPI TNFRSF14 TRIM8 TRMT61A USP3 VPS29 WWP2
Impedance of leg (left) 1.28 54 35 106.1 -0.37 5.1e-03 AC005104.3 AC006547.14 AC010883.5 AC034102.1 AC074117.10 AC103965.1 ACBD4 ARID2 CTC-228N24.3 DCAKD DCST2 DOC2A EP300 ERMP1 GIMAP7 GS1-393G12.12 HEMK1 HSD3B7 ITIH4-AS1 JUND LIN7C LOC595101 LPAR2 LRRC25 MARK1 MUS81 PACSIN1 PARP12 PDPR PHC2 PLA2G15 PLEKHM1 POM121C PPP4C RBM6 RIN3 RNF185 RP11-231C14.4 RP11-393I2.4 RP11-425D10.10 RPN1 SCNM1 SEMA3B-AS1 SETD8 TEAD3 TOM1L2 TP53INP1 TRIM8 TSPAN3 UBR2 USP3 ZBTB24 ZC3HAV1 ZNF652
Leg predicted mass (left) 1.44 60 43 130.3 0.54 1.5e-06 ABCB9 AC005104.3 AC034102.1 AC074117.10 ACBD4 ARHGEF19-AS1 ARID2 C14orf39 C16orf93 CD164 CDC42SE2 CDK2AP1 CDK6 CEP85 CPEB4 CRTAP CTC-228N24.3 DCST2 DOC2A EFEMP2 FAM133B GATAD1 GNA12 GPN3 HIVEP3 HSD3B7 KRIT1 LIN7C LOC595101 MRPS31 NFKBIA NOSTRIN P4HA2-AS1 PACSIN1 PARP12 PDLIM4 PHC2 PLCD3 PPP4C PPTC7 RBM6 RIN3 RMND1 RP11-231C14.4 RP11-282O18.3 RP11-425D10.10 RPN1 RSBN1L-AS1 SEPT2 SETD8 SH2B3 SH3GL1P3 SLC22A5 SMPD2 TEAD3 TRIM8 UPF3A VPS29 ZBTB24 ZRANB1
Trunk fat mass 1.21 42 30 90.9 -0.06 6.9e-01 AC103965.1 ACO2 ARIH2 C16orf93 C17orf58 CDK6 CENPO DESI1 DLG4 DOC2A FAM133B FAM212A GNA12 GPN3 HIVEP3 HSD3B7 JUND LIN7C LOC595101 LRRC25 MAP2K2 MAP2K5 MAPK13 PACS1 PACSIN1 PAPD7 PDPR POM121C PPARG PPP4C PPTC7 RBM6 RP11-138A9.1 RP11-231C14.4 RP11-981P6.1 RP5-1115A15.1 RSBN1L-AS1 SH3GL1P3 SMAD3 UPF3A WBP2 WWP2
Waist circumference 1.25 34 27 81.8 -0.03 8.6e-01 AC034102.1 C16orf93 C17orf58 CDK6 CENPO CLDN7 DLG4 DOC2A FAM212A HSD3B7 IFITM2 JUND LIN7C LOC595101 LRRC25 MAP2K2 MAP2K5 PACSIN1 PAFAH1B2 PDPR PHC2 PNPO POM121C PPP4C RBM6 RP11-231C14.4 RP11-296I10.3 RP11-981P6.1 SH3GL1P3 SMAD3 TEAD3 TFPI WWP2 ZNHIT3
Number of incorrect matches in round 1.06 4 4 12.1 -0.99 1.5e-02 DOC2A LOC595101 PPP4C RP11-231C14.4
Past tobacco smoking 0.99 3 1 3.0 0.00 1.0e+00 PHC2 RAD54L2 SH2B3
Alcohol usually taken with meals 1.07 3 0 0.0 0.00 1.0e+00 GRPEL1 POR RMI1
Nervous feelings 1.05 6 2 6.1 0.38 4.6e-01 DOC2A FRAT1 LIN7C MYO1H PLEKHM1 PPP4C
Frequency of tenseness / restlessness in last 2 weeks 1.11 2 1 3.0 0.00 1.0e+00 GPX1 PLEKHM1
Hearing difficulty/problems with background noise 1.06 2 0 0.0 0.00 1.0e+00 PLEKHM1 RPS6KB1
Hair/balding pattern: Pattern 2 0.98 2 1 3.0 0.00 1.0e+00 CLIC4 PLEKHM1
Had menopause 1.13 1 0 0.0 0.00 1.0e+00 IFI35
Forced vital capacity (FVC) 1.17 34 26 78.8 0.35 3.5e-02 AC005104.3 ARNT CACFD1 CCR4 CDK6 CENPO CEP85 CLDN7 CRHR1-IT1 CTC-228N24.3 CXCL17 DARS FAM133B GATAD1 GNA12 MAP2K2 MAPK13 PACSIN1 PDPR PLEKHM1 PSMC3 REST RIN3 RP11-296I10.3 RP11-425D10.10 SEPT2 SMPD2 SRPK1 TEAD3 UBE2Z WAC-AS1 WWP2 ZBTB24 ZNF76
Heel bone mineral density (BMD) T-score, automated (right) 1.14 13 9 27.3 -0.03 9.3e-01 AKAP11 ARHGEF19-AS1 CDK6 EP300 FADS1 FAM212A GATAD1 MAP3K11 RBM6 RP4-800G7.2 RP5-1115A15.1 SLC9A5 TRMT61A
Ever unenthusiastic/disinterested for a whole week 1.18 3 0 0.0 0.00 1.0e+00 PLEKHM1 SYN2 TIMP4
Qualifications: None of the above 1.04 6 5 15.2 -0.53 2.2e-01 ABCB9 AC034102.1 CDK2AP1 RBM6 RP11-282O18.3 SETD8
Mouth/teeth dental problems 1.14 3 0 0.0 0.00 1.0e+00 CXCR6 MYO1H SLC13A4
Allergy 4.41 87 68 206.1 0.88 8.0e-35 ABCB9 AC034102.1 AC093642.3 AC114730.7 ACO2 ACSL6 AHI1 B4GALT3 BACH2 CARD11 CCR4 CD247 CDK2AP1 CLEC16A CLIC4 D2HGDH DESI1 DEXI EFEMP2 EP300 ERMP1 FADS1 FAM55C FOXO1 GLDC GNA12 GSDMB HHEX IL18R1 IL1R1 IL1RL2 IL2RA IL33 IL4R IL7R KIAA1109 KIAA1432 KIF11 KIF3A KRT1 LCLAT1 LOC729082 LRP1 LRRC32 MED24 MUS81 NDFIP1 NDUFAF1 NHP2L1 NRROS NUSAP1 OIP5-AS1 P4HA2-AS1 PDLIM4 PLGRKT PMM1 POLI POLR3H PPP1R1B PRKCQ PRKRIR PSMB7 RAD50 RBBP8 RGS14 RMI2 RP11-282O18.3 RP11-396B14.2 RP11-502I4.3 RP11-876N24.4 RP11-876N24.5 RP5-1115A15.1 SETD8 SIK2 SLC22A5 SLC25A46 SMAD3 SMAD4 SMARCE1 SPATA5 SPPL3 THRA TNFRSF14 TSLP UBAC2 WDR36 ZNF652
Diabetes (self-reported) 1.24 6 4 12.1 0.70 5.1e-02 AC010883.5 EIF2S2P3 FAM212A HHEX KIF11 RBM6
Hayfever/allergic rhinitis (self-reported) 2.40 20 13 39.4 -0.93 7.8e-11 AC093642.3 AC114730.7 B4GALT3 BACH2 CD247 CLEC16A D2HGDH DEXI GLDC IL18R1 IL1RL2 IL7R KIAA1109 LRRC32 RP11-396B14.2 SLC25A46 SMAD3 SPATA5 TSLP WDR36
Medication: Simvastatin 1.28 5 5 15.2 0.56 3.2e-01 CARM1 LPL PVRL2 TOMM40 ZNF259
Fluid intelligence score 0.96 4 2 6.1 0.98 2.2e-03 ABCB9 FRAT1 RBM6 RP11-282O18.3
Illnesses of siblings 1.18 2 0 0.0 0.00 1.0e+00 HSD3B7 SH2B3
Neuroticism score 1.16 6 3 9.1 0.52 2.3e-01 ACO2 MYO1H PLCL2 PLEKHM1 RP5-1115A15.1 SYN2
Weight 1.34 53 40 121.2 0.34 8.1e-03 AC005104.3 AC034102.1 AC074117.10 ACBD4 C14orf39 C16orf93 C17orf58 CD164 CDK2AP1 CDK6 DOC2A EFEMP2 FAM133B FOXO1 GATAD1 GNA12 GPN3 HIVEP3 HSD3B7 KRIT1 LIN7C LOC595101 MAP2K5 NFKBIA NOSTRIN P4HA2-AS1 PACS1 PACSIN1 PAPD7 PDLIM4 PHC2 POM121C PPP4C PPTC7 RBM6 RP11-231C14.4 RP11-282O18.3 RP11-425D10.10 RP11-617D20.1 RP11-981P6.1 RSBN1L-AS1 SEPT2 SETD8 SH3GL1P3 SLC22A5 SMAD3 SMPD2 TEAD3 TNFRSF14 TRIM8 UPF3A VPS29 ZBTB24
Impedance of arm (right) 1.29 66 48 145.5 -0.41 3.8e-04 AC006547.14 AC034102.1 AC074117.10 AC103965.1 ACBD4 ACO2 AKAP13 ARID2 ARIH2 ARNT CRHR1-IT1 CSDC2 DCAKD DCST2 DESI1 DOC2A EFEMP2 EP300 GBGT1 GPN3 GPX1 GS1-393G12.12 HEMK1 HSD3B7 ITIH4-AS1 JUND LCLAT1 LIN7C LOC342346 LOC595101 LPAR2 LRRC25 LRRC32 MCL1 MED24 MUS81 NHP2L1 PACSIN1 PHC2 PLA2G15 PLEKHM1 PMM1 POLR3H PPP4C PPTC7 PSMB7 RAB7A RBM6 RIN3 RMI1 RNF185 RNF215 RP11-231C14.4 RP11-393I2.4 RP11-502I4.3 RP13-131K19.6 SCNM1 SEMA3B-AS1 SYN2 TEAD3 TRIM8 TRMT61A TSPAN3 UPF3A VPS29 ZNF652
Arm fat percentage (right) 1.20 37 27 81.8 -0.32 4.3e-02 ACO2 C16orf93 C17orf58 CENPO DLG4 DOC2A FAM212A HSD3B7 JUND LIN7C LOC595101 LOC729082 LRRC25 MAP2K2 MAP2K5 MAPK13 NDUFAF1 NUSAP1 OIP5-AS1 PDPR POM121C PPARG PPP4C RBM6 RP11-138A9.1 RP11-231C14.4 RP11-296I10.3 RP11-981P6.1 RP5-1115A15.1 SH3GL1P3 SMAD3 TEAD3 USP3 WBP2 WWP2 ZNF76 ZNHIT3
Trunk fat-free mass 1.58 77 60 181.8 0.54 3.3e-08 ABCB9 AC005104.3 AC034102.1 AC074117.10 ACBD4 ADAM1A AKAP13 ARID2 BRD3 C14orf39 CD164 CDK2AP1 CDK6 CENPO CEP85 CTC-228N24.3 CUX2 DCAKD DESI1 DOC2A EFEMP2 FAM133B GATAD1 GLS2 GNA12 GPN3 HIVEP3 HSD3B7 KRIT1 LBX2-AS1 LIN7C LOC342346 LOC595101 LRRC25 LUZP1 MAX NFATC3 NFKBIA NOSTRIN P4HA2-AS1 PACSIN1 PAPD7 PARP12 PDLIM4 PHC2 PLCD3 PPP4C PPTC7 PRTFDC1 PSMB7 PSMC3 PTEN RBM6 REST RIN3 RMND1 RP11-231C14.4 RP11-282O18.3 RP11-425D10.10 SBNO1 SEC16A SEPT2 SETD8 SH2B3 SLC22A5 SMPD2 SOX15 SRPK1 TEAD3 TRIM8 UBE2Z VPS29 WAC-AS1 ZBTB24 ZNF414 ZNF76 ZRANB1
Hip circumference 1.29 44 32 97.0 0.30 3.6e-02 ABCB9 ANKRD36C C16orf93 C17orf58 CDK6 CENPO CPEB4 DLG4 DOC2A FAM133B GATAD1 GNA12 GPN3 HIVEP3 HSD3B7 KCNJ2 LIN7C LOC595101 MAP2K2 MAPKAPK5-AS1 PACS1 PACSIN1 PDPR PHC2 POM121C PPP4C PPTC7 RBM6 RP11-138A9.1 RP11-231C14.4 RP11-981P6.1 RSBN1L-AS1 SH2B3 SH3GL1P3 SMAD3 SMPD2 TEAD3 TRIM8 UBR2 UPF3A VPS29 WBP2 WWP2 ZBTB24
Alcohol intake versus 10 years previously 1.05 2 1 3.0 0.00 1.0e+00 DOC2A RBM6
Father's age at death 1.35 1 1 3.0 0.00 1.0e+00 SH2B3
Worrier / anxious feelings 1.00 6 2 6.1 0.47 3.4e-01 ITIH4-AS1 MYO1H PLEKHM1 PPP4C SEMA3B-AS1 TEAD3
Frequency of tiredness / lethargy in last 2 weeks 1.16 7 2 6.1 -0.06 8.9e-01 ACO2 GPX1 LIN7C MYO1H TCTA UBE2Z UNG
Hair/balding pattern: Pattern 3 0.91 2 1 3.0 0.00 1.0e+00 CRHR1-IT1 PLEKHM1
Number of live births 1.02 2 0 0.0 0.00 1.0e+00 FADS1 PLEKHM1
Forced expiratory volume in 1-second (FEV1) 1.22 29 20 60.6 0.48 6.3e-03 AC034102.1 C20orf112 CACFD1 CDK6 CENPO CEP85 CRHR1-IT1 CXCL17 DARS GPX1 MAPK13 NFKBIA PACSIN1 PDPR PLEKHM1 REST RIN3 RNF185 RP11-296I10.3 RP11-425D10.10 SEC24C SLC22A5 SMPD2 SRPK1 TEAD3 WAC-AS1 WWP2 ZBTB24 ZNF76
Pulse rate 1.06 3 3 9.1 0.00 1.0e+00 FADS1 FAM212A GIGYF1
Qualifications: A levels/AS levels or equivalent 1.07 8 5 15.2 0.56 1.1e-01 ABCB9 CDK2AP1 GPX1 PLEKHM1 POM121C RBM6 RP11-282O18.3 SETD8
Mouth/teeth dental problems: Dentures 1.09 2 0 0.0 0.00 1.0e+00 B4GALT3 RBM6
Asthma 4.10 58 45 136.4 -0.89 3.8e-27 AC034102.1 AC093642.3 AC114730.11 AC114730.7 ACO2 ACSL6 AHI1 B4GALT3 BACH2 CARM1 CD247 CLEC16A D2HGDH DESI1 DEXI EIF2S2P3 ERMP1 FADS1 GLDC HHEX IL18R1 IL1R1 IL1RL2 IL33 IL4R KIAA1109 KIAA1432 KIF11 KIF3A LRP1 LRRC32 MED24 NDFIP1 NHP2L1 NRROS NUSAP1 P4HA2-AS1 PDLIM4 POLR3H PPP1R1B PRKRIR RAD50 RP11-396B14.2 RP11-876N24.4 RP11-876N24.5 RP5-1115A15.1 SIK2 SLC22A5 SLC25A46 SMAD3 SMAD4 SPPL3 THRA TSLP UBAC2 WDR36 ZNF652 ZNF76
Medication: Ibuprofen (e.g. Nurofen) 1.01 1 1 3.0 0.00 1.0e+00 LRP1
Medication: Cholesterol lowering 1.25 5 4 12.1 0.59 3.0e-01 CARM1 LPL PVRL2 TOMM40 ZNF259
Depression (self-reported) 0.99 1 0 0.0 0.00 1.0e+00 RP5-1115A15.1
Illnesses of mother 1.05 2 1 3.0 0.00 1.0e+00 MED24 UBE2Z
Forced expiratory volume in 1-second (FEV1), Best measure 1.25 27 18 54.5 0.51 4.0e-03 AC034102.1 C20orf112 C5orf34 CACFD1 CDK6 CEP85 CRHR1-IT1 CXCL17 DARS GPX1 MAPK13 PACSIN1 PDPR PLEKHM1 REST RIN3 RP11-296I10.3 RP11-425D10.10 SEC24C SLC22A5 SMPD2 SRPK1 TEAD3 WAC-AS1 WWP2 ZBTB24 ZNF76
Impedance of arm (left) 1.29 60 45 136.4 -0.35 4.7e-03 AC006547.14 AC034102.1 AC074117.10 AC103965.1 ACBD4 ACO2 AKAP13 ARID2 ARIH2 ARNT CRHR1-IT1 CSDC2 DCAKD DESI1 DOC2A EFEMP2 EP300 GPN3 GPX1 GS1-393G12.12 HEMK1 HSD3B7 ITIH4-AS1 JUND LIN7C LOC342346 LOC595101 LPAR2 LRRC25 LRRC32 MCL1 MUS81 NHP2L1 PACSIN1 PHC2 PLEKHM1 PMM1 POLR3H PPP4C PSMA6 PSMB7 RBM6 RIN3 RMI1 RNF185 RNF215 RP11-231C14.4 RP11-393I2.4 RP11-502I4.3 RP13-131K19.6 SCNM1 SEMA3B-AS1 SH2B3 TCTA TEAD3 TNIP2 TRIM8 TSPAN3 VPS29 ZNF652
Arm fat mass (right) 1.21 36 24 72.7 0.03 8.5e-01 AC034102.1 ACO2 C16orf93 C17orf58 CDK6 CENPO DLG4 DOC2A FAM212A GPN3 HSD3B7 JUND LIN7C LOC595101 LRRC25 MAP2K2 MAP2K5 PACS1 PACSIN1 PDPR PHC2 POM121C PPP4C PPTC7 RBM6 RP11-231C14.4 RP11-296I10.3 RP11-981P6.1 RP5-1115A15.1 RSBN1L-AS1 SH3GL1P3 SMAD3 TEAD3 TRIM8 VPS29 WWP2
Trunk predicted mass 1.59 75 60 181.8 0.55 3.4e-08 ABCB9 AC005104.3 AC034102.1 AC074117.10 ACBD4 ADAM1A AKAP13 ARID2 BRD3 C14orf39 CD164 CDK2AP1 CDK6 CENPO CEP85 CTC-228N24.3 CUX2 DCAKD DESI1 DOC2A EFEMP2 FAM133B GATAD1 GLS2 GNA12 GPN3 HSD3B7 KRIT1 LIN7C LOC342346 LOC595101 LRRC25 LUZP1 MAX NFATC3 NFKBIA NOSTRIN P4HA2-AS1 PACSIN1 PAPD7 PARP12 PDLIM4 PHC2 PLCD3 PPP4C PPTC7 PRTFDC1 PSMB7 PSMC3 PTEN RBM6 REST RIN3 RMND1 RP11-231C14.4 RP11-282O18.3 RP11-425D10.10 SBNO1 SEC16A SEPT2 SETD8 SH2B3 SLC22A5 SMPD2 SOX15 SRPK1 TEAD3 TRIM8 UBE2Z VPS29 WAC-AS1 ZBTB24 ZNF414 ZNF76 ZRANB1
Standing height 1.43 125 97 293.9 0.36 8.5e-06 ABCB9 AC005104.3 AC021860.1 AC063976.3 AC103965.1 AC113189.5 ACBD4 ACSL6 ADO APOC2 ARHGEF19-AS1 ARIH2 BRD3 CA14 CACFD1 CACNA1H CCNO CCR4 CD164 CDK2AP1 CDK6 CENPO CEP85 COG6 COX4I2 CRTAP CXCL17 DCAKD DESI1 DOC2A EBPL EFCAB13 ELF1 FADS1 FAM133B GATAD1 GIGYF1 GLS2 GNA12 HEMK1 HIVEP3 IFI35 IL1R1 ITIH4-AS1 KIF17 KRIT1 LBX2-AS1 LOC729082 LPAR2 LRP1 LUZP1 MAP2K2 MAP3K11 MAX MKRN2 MRPS31 NDUFAF1 NFKBIA NOSTRIN NUCB2 NUSAP1 OIP5-AS1 P4HA2-AS1 PACSIN1 PAPD7 PARP12 PDLIM4 PDPR PHC2 PLCD3 PLEKHM1 PPARA PPP3CC PPP4C PSMC3 PTEN PUS10 RAD50 RBBP8 REST RGS14 RMI1 RMND1 RP11-231C14.4 RP11-282O18.3 RP11-296I10.3 RP11-425D10.10 RP13-131K19.6 RP4-756G23.5 RP5-1085F17.3 RP5-1115A15.1 RPL32P3 SBNO1 SEC16A SEPT2 SETD8 SH2B3 SH3GL1P3 SLC11A2 SLC13A4 SLC22A5 SMPD2 SOX15 SPPL3 SRPK1 STOX1 SUGT1L1 TCTA TEAD3 TLR1 TRMT61A TRPC1 TSEN2 TSPAN3 UBE2Z UPF3A USP3 WAC-AS1 WWP2 ZBTB24 ZNF414 ZNF76 ZNF783 ZNF786 ZRANB1
Breastfed as a baby 1.23 1 0 0.0 0.00 1.0e+00 PSMB7
Tense / 'highly strung' 1.13 3 2 6.1 0.47 5.3e-01 ACO2 RP5-1115A15.1 ZSCAN29
Hair/balding pattern: Pattern 4 0.92 9 6 18.2 -0.35 3.5e-01 ATG5 CLIC4 CRHR1-IT1 DCAKD EXOC2 FADS1 PLEKHM1 POLI RP5-1115A15.1
Birth weight of first child 1.34 6 4 12.1 0.71 1.2e-01 DLG4 MAPKAPK5-AS1 RP11-158M2.3 SH2B3 TEAD3 ZNF76
Peak expiratory flow (PEF) 1.10 9 7 21.2 0.25 5.1e-01 AC010883.5 CACFD1 MAST1 PLEKHM1 RP11-425D10.10 SMPD2 TRPC1 ZBTB24 ZNF76
Ever highly irritable/argumentative for 2 days 1.08 1 0 0.0 0.00 1.0e+00 RBM6
Qualifications: O levels/GCSEs or equivalent 1.05 5 3 9.1 0.77 7.4e-02 ABCB9 CDK2AP1 LYG1 RP11-282O18.3 SETD8
Blood clot in the leg (DVT) 1.10 2 2 6.1 0.00 1.0e+00 CACFD1 GBGT1
Medication: Paracetamol 1.15 2 2 6.1 0.00 1.0e+00 LRP1 PLEKHM1
Headache pain in last month 1.27 7 5 15.2 0.76 4.8e-02 AC034102.1 ACBD4 FAM216A LRP1 MRPS21 PLEKHM1 PPP1CC
Medication for cholesterol, blood pressure or diabetes 1.25 5 4 12.1 0.60 2.9e-01 RRP1B SH2B3 SIK2 TSPY26P ZNF259
Gout (self-reported) 1.17 3 2 6.1 0.00 1.0e+00 MAP3K11 SH2B3 WWP2
Hypothyroidism/myxoedema (self-reported) 2.16 28 16 48.5 -0.52 3.0e-03 AC005104.3 AC034102.1 AC093642.3 AC114730.7 ADAM1A ASB13 BACH2 C1QTNF6 CD247 CHD7 DOK6 EFCAB13 FCHO2 LRRC25 MAPKAPK5-AS1 PPP1R14B PSMB7 RASGRP1 RP5-1115A15.1 SEPT2 SESN1 SH2B3 SYN2 TCEB3 TCHP TCTN1 TIMP4 VPS29
Medication: Amlodipine 1.20 1 0 0.0 0.00 1.0e+00 AC113189.5
Medication: Ventolin 100micrograms inhaler 2.43 16 7 21.2 -0.92 1.3e-07 AC093642.3 AC114730.7 AHI1 BACH2 CD247 CLEC16A D2HGDH DEXI FOXO1 GLDC IL18R1 IL1RL2 LRRC32 PPP1R1B PRKRIR SMAD3
Birth weight 1.62 19 12 36.4 0.00 1.0e+00 ACAP1 CDK6 CLDN7 DLG4 EIF2S2P3 GNA12 HHEX KIF11 MAPK13 RP11-158M2.3 RP11-425D10.10 RP5-1085F17.3 SESN1 SH2B3 SIK2 SRPK1 TEAD3 TNFSF13 ZNF76
High blood pressure (siblings) 1.20 2 0 0.0 0.00 1.0e+00 HSD3B7 SH2B3
Forced vital capacity (FVC), Best measure 1.17 31 24 72.7 0.36 3.6e-02 AC005104.3 ARNT C5orf34 CACFD1 CDK6 CENPO CEP85 CRHR1-IT1 CTC-228N24.3 CXCL17 DARS FAM133B GATAD1 GNA12 MAPK13 PACSIN1 PDPR PLEKHM1 PSMC3 REST RIN3 RP11-296I10.3 RP11-425D10.10 SEPT2 SMPD2 SRPK1 TEAD3 WAC-AS1 WWP2 ZBTB24 ZNF76
Body fat percentage 1.27 42 33 100.0 -0.39 8.2e-03 AC103965.1 ACO2 C16orf93 C17orf58 CENPO CTC-228N24.3 CXCL17 DARS DCAKD DESI1 DOC2A FAM212A HSD3B7 JUND LIN7C LOC595101 LOC729082 LRRC25 MAP2K2 MAP2K5 MAPK13 NDUFAF1 NUSAP1 OIP5-AS1 PACS1 PDPR POLR3H POM121C PPARG PPP4C RBM6 RIN3 RP11-138A9.1 RP11-231C14.4 RP11-296I10.3 RP11-981P6.1 RP5-1115A15.1 RSBN1L-AS1 SH3GL1P3 SMAD3 TEAD3 WWP2
Leg fat percentage (right) 1.33 41 29 87.9 -0.49 9.6e-04 ATP9A C17orf58 CENPO CTC-228N24.3 CXCL17 DARS DCAKD DLG4 DOC2A FAM212A GPX1 HSD3B7 JUND LIN7C LOC729082 LRP1 LRRC25 MAP2K2 MAP2K5 MAPK13 NDUFAF1 NUSAP1 OIP5-AS1 PACS1 PDPR PLGRKT POM121C PSMC3 RBM6 RIN3 RP11-138A9.1 RP11-231C14.4 RP11-296I10.3 RP11-867G23.2 RP11-981P6.1 RP5-1115A15.1 SH3GL1P3 SMAD3 TEAD3 TFPI WWP2
Arm fat-free mass (right) 1.50 66 50 151.5 0.57 3.4e-08 ABCB9 AC005104.3 AC006547.14 AC034102.1 AC074117.10 ACBD4 ADAM1A AKAP13 ARID2 C14orf39 CD164 CDK2AP1 CDK6 CEP85 CUX2 DCAKD DOC2A EFEMP2 FAM133B GATAD1 GNA12 GPN3 GPX1 HIVEP3 HSD3B7 KRIT1 LIN7C LOC595101 LUZP1 MAX NFATC3 NFKBIA NOSTRIN P4HA2-AS1 PACSIN1 PAPD7 PARP12 PDLIM4 PHC2 PLCD3 PPP4C PPTC7 PSMB7 RAPGEF1 RBM6 RIN3 RP11-231C14.4 RP11-282O18.3 RP11-425D10.10 RSBN1L-AS1 SEC16A SEPT2 SETD8 SH2B3 SLC22A5 SMPD2 SOX15 TEAD3 TRIM8 UBE2Z VPS29 WAC-AS1 ZBTB24 ZNF414 ZNF76 ZRANB1
Comparative body size at age 10 1.28 16 7 21.2 0.16 5.4e-01 ADRA2B C16orf93 C5orf34 CENPO DOC2A EP300 FAHD2CP LIN7C LOC595101 MAP3K11 NEURL1B NHP2L1 RP11-231C14.4 SMAD3 TEAD3 TMEM127
Worry too long after embarrassment 1.03 2 1 3.0 0.00 1.0e+00 MYO1H PLEKHM1
Seen a psychiatrist for nerves, anxiety, tension or depression 1.06 1 0 0.0 0.00 1.0e+00 SYN2
Wheeze or whistling in the chest in last year 2.24 27 20 60.6 -0.91 6.1e-12 AC093642.3 AC114730.7 BACH2 CD247 CLEC16A D2HGDH DEXI GLDC IL18R1 IL1R1 IL1RL2 IL33 KIAA1432 LIN7C LRP1 LRRC32 MED24 NRROS PPP1R1B RBM6 RP11-396B14.2 RP11-876N24.5 SIK2 SMAD3 THRA TSLP UBAC2
Age at first live birth 1.05 3 1 3.0 0.00 1.0e+00 GPX1 RBM6 RP13-131K19.6
Shortness of breath walking on level ground 1.06 1 0 0.0 0.00 1.0e+00 LRRC32
Qualifications: College or University degree 1.02 20 13 39.4 -0.11 6.4e-01 ABCB9 AC005786.7 AC034102.1 CACNA1H CDK2AP1 CRHR1-IT1 DR1 FAM212A GPX1 HSD3B7 JUND LRRC25 PLEKHM1 RBM6 RP11-282O18.3 RP11-298I3.1 RP13-131K19.6 SETD8 TNIP2 TRMT61A
Eye problems/disorders: None of the above 1.09 1 0 0.0 0.00 1.0e+00 B4GALNT4
Medication for pain relief, constipation, heartburn 1.10 3 2 6.1 0.00 1.0e+00 ABCB9 LRP1 PLEKHM1
Medication: Blood pressure 1.25 5 4 12.1 -0.76 1.3e-01 DLG4 RRP1B SH2B3 SIK2 TSPY26P
Migraine (self-reported) 1.13 1 1 3.0 0.00 1.0e+00 LRP1
Medication: Ibuprofen 0.99 1 1 3.0 0.00 1.0e+00 LRP1
Medication: Allopurinol 1.14 1 0 0.0 0.00 1.0e+00 MAP3K11
Medication: Seretide 50 evohaler 1.62 4 0 0.0 -0.99 1.0e-02 D2HGDH IL18R1 P4HA2-AS1 SLC22A5
Mean time to correctly identify matches 1.13 6 3 9.1 -0.84 3.8e-02 CLDN7 DLG4 MAPKAPK5-AS1 NBEAL2 RMI1 SH2B3
Whole body fat mass 1.22 40 28 84.8 0.08 6.4e-01 AC034102.1 ACO2 C16orf93 C17orf58 CDK6 CENPO DARS DOC2A FAM212A GNA12 GPN3 HIVEP3 HSD3B7 JUND LIN7C LOC595101 LRRC25 MAP2K2 MAP2K5 PACS1 PACSIN1 PAPD7 PDPR PHC2 POM121C PPARG PPP4C PPTC7 RBM6 RP11-231C14.4 RP11-296I10.3 RP11-981P6.1 RP5-1115A15.1 RSBN1L-AS1 SH3GL1P3 SMAD3 TRIM8 UPF3A VPS29 WWP2
Leg fat mass (right) 1.24 41 27 81.8 0.18 2.5e-01 AC034102.1 C16orf93 C17orf58 CD164 CDK6 CENPO DARS DOC2A EFEMP2 FAM212A GPN3 GPX1 HSD3B7 JUND LIN7C LOC595101 LRRC25 MAP2K2 MAP2K5 PACS1 PACSIN1 PAPD7 PDPR PHC2 POM121C PPP4C PPTC7 RBM6 RP11-231C14.4 RP11-867G23.2 RP11-981P6.1 RP5-1115A15.1 RSBN1L-AS1 SH3GL1P3 SMAD3 TEAD3 TFPI TNFRSF14 TRIM8 VPS29 WWP2
Arm predicted mass (right) 1.52 69 50 151.5 0.55 4.3e-08 ABCB9 AC005104.3 AC006547.14 AC034102.1 AC074117.10 ACBD4 ADAM1A AKAP13 ARID2 C14orf39 C16orf93 CD164 CDK2AP1 CDK6 CEP85 CUX2 DCAKD DCST2 DOC2A EFEMP2 FAM133B GATAD1 GNA12 GPN3 GPX1 HSD3B7 KRIT1 LIN7C LOC342346 LOC595101 LUZP1 MAX MED24 NFATC3 NFKBIA NOSTRIN P4HA2-AS1 PACSIN1 PAPD7 PARP12 PDLIM4 PHC2 PLCD3 PPP4C PPTC7 PSMB7 RAPGEF1 RBM6 RIN3 RP11-231C14.4 RP11-282O18.3 RP11-425D10.10 SEC16A SEPT2 SETD8 SH2B3 SH3GL1P3 SLC22A5 SMPD2 SOX15 TEAD3 TRIM8 UBE2Z VPS29 WAC-AS1 ZBTB24 ZNF414 ZNF76 ZRANB1
Pulse rate, automated reading 1.22 20 13 39.4 -0.30 1.6e-01 AC034102.1 ADRA2B ARIH2 ARNT C16orf93 CSTA FADS1 FAM212A GIGYF1 GPN3 ITPRIPL1 PPTC7 RBM6 RP13-131K19.6 SLC13A4 SLC7A8 TCTA TFPI TOM1L2 VPS29
Alcohol intake frequency. 1.06 12 5 15.2 0.09 7.9e-01 ABCB9 AC074117.10 C16orf93 DOC2A HSD3B7 LRP1 PLEKHM1 PPP4C RBM6 RP11-282O18.3 SETD8 WWP2
Comparative height size at age 10 1.32 60 43 130.3 0.46 9.8e-05 ABCB9 AC005104.3 AC010883.5 AC103965.1 ACBD4 ACSL6 CCR4 CDK2AP1 CDK6 CENPO CEP85 CRTAP CUX2 DOC2A FAM133B GATAD1 GNA12 KIF11 KIF17 KRIT1 LBX2-AS1 MAP2K2 MAX NFKBIA NOSTRIN NOXRED1 NUCB2 P4HA2-AS1 PACSIN1 PAPD7 PDLIM4 PLCD3 PLEKHM1 PPP4C PSMC3 RBBP8 RMI1 RP11-231C14.4 RP11-282O18.3 RP11-425D10.10 RP5-1085F17.3 SBNO1 SEC16A SEPT2 SETD8 SH2B3 SH3GL1P3 SLC13A4 SLC22A5 SRPK1 SUGT1L1 TEAD3 TSPAN3 UBE2Z UPF3A ZBTB24 ZNF260 ZNF414 ZNF76 ZRANB1
Number of full sisters 1.06 1 0 0.0 0.00 1.0e+00 TNIP2
Overall health rating 1.04 7 4 12.1 -0.76 4.7e-02 C17orf58 GPX1 POM121C RBM6 SH3GL1P3 TOM1L2 TSPY26P
Chest pain or discomfort 1.15 1 0 0.0 0.00 1.0e+00 THRA
Age at last live birth 1.04 1 1 3.0 0.00 1.0e+00 RBM6
Leg pain on walking 1.01 1 1 3.0 0.00 1.0e+00 RBM6
Qualifications: NVQ or HND or HNC or equivalent 1.19 1 0 0.0 0.00 1.0e+00 RBM6
Knee pain experienced in last month 1.10 1 0 0.0 0.00 1.0e+00 RP11-981P6.1
Hypertension (Self-reported) 1.30 22 9 27.3 -0.71 1.9e-04 AC021860.1 ADRB2 DLG4 DOC2A HSD3B7 MAPKAPK5-AS1 P4HA2-AS1 PDLIM4 PSMC3 RP11-138A9.1 RP11-617D20.1 RP5-1115A15.1 RRP1B SH2B3 SIK2 SLC22A5 TMEM116 TP53INP1 TSPY26P UBE2Z WBP2 ZDHHC18
Illnesses of father: Heart disease 1.18 1 0 0.0 0.00 1.0e+00 SMAD3
Illnesses of siblings: Diabetes 1.31 1 0 0.0 0.00 1.0e+00 EIF2S2P3
Smoking status: Previous 0.95 1 0 0.0 0.00 1.0e+00 SH2B3
Forced expiratory volume in 1-second (FEV1), predicted 1.22 12 10 30.3 0.53 7.7e-02 AC103965.1 CDK6 FAM133B GNA12 NOSTRIN P4HA2-AS1 PACSIN1 PDLIM4 SEC16A SLC22A5 TEAD3 ZNF76
Whole body fat-free mass 1.54 72 55 166.7 0.56 2.5e-08 ABCB9 AC005104.3 AC034102.1 AC074117.10 ACBD4 ARID2 BRD3 C14orf39 CD164 CDC42SE2 CDK2AP1 CDK6 CEP85 CTC-228N24.3 CUX2 DCAKD DCST2 DESI1 DOC2A EFEMP2 FAM133B GATAD1 GNA12 GPN3 HIVEP3 HSD3B7 KRIT1 LIN7C LOC342346 LOC595101 LUZP1 LYRM7 MAX NFATC3 NFKBIA NOSTRIN P4HA2-AS1 PACSIN1 PAPD7 PARP12 PDLIM4 PHC2 PLCD3 PPP4C PPTC7 PSMC3 RBM6 REST RIN3 RMND1 RP11-231C14.4 RP11-282O18.3 RP11-425D10.10 RSBN1L-AS1 SEC16A SEPT2 SETD8 SH2B3 SLC22A5 SMPD2 SOX15 SRPK1 TEAD3 TRIM8 UBE2Z UPF3A VPS29 WAC-AS1 ZBTB24 ZNF414 ZNF76 ZRANB1
Leg fat-free mass (right) 1.48 63 48 145.5 0.50 7.4e-06 ABCB9 AC005104.3 AC006547.14 AC034102.1 AC074117.10 ACBD4 ARID2 C14orf39 C16orf93 CD164 CDC42SE2 CDK2AP1 CDK6 CEP85 CPEB4 CRTAP CTC-228N24.3 DCST2 DOC2A EFCAB13 EFEMP2 FAM133B GATAD1 GNA12 GPN3 HIVEP3 HSD3B7 KRIT1 LIN7C LOC595101 MRPS31 NFKBIA NOSTRIN P4HA2-AS1 PACSIN1 PARP12 PDLIM4 PHC2 PLCD3 PPP4C PPTC7 RBM6 RIN3 RMND1 RP11-231C14.4 RP11-282O18.3 RP11-425D10.10 RP11-617D20.1 RP11-981P6.1 RPN1 RSBN1L-AS1 SEPT2 SETD8 SH2B3 SLC22A5 SMPD2 SRPK1 TEAD3 TRIM8 UPF3A VPS29 ZBTB24 ZRANB1
Arm fat percentage (left) 1.22 38 28 84.8 -0.37 1.8e-02 ACO2 C16orf93 C17orf58 CENPO DESI1 DLG4 DOC2A FAM212A HSD3B7 JUND LIN7C LOC595101 LOC729082 LRRC25 MAP2K2 MAP2K5 MAPK13 NDUFAF1 NUSAP1 OIP5-AS1 PDPR POLR3H POM121C PPARG PPP4C RBM6 RP11-138A9.1 RP11-231C14.4 RP11-296I10.3 RP11-981P6.1 RP5-1115A15.1 SH3GL1P3 SMAD3 TEAD3 USP3 WBP2 WWP2 ZNF76
Average weekly red wine intake 1.06 1 0 0.0 0.00 1.0e+00 RP11-282O18.3
Handedness (chirality/laterality): Left-handed 0.94 1 1 3.0 0.00 1.0e+00 PLEKHM1
Mood swings 1.07 7 2 6.1 -0.13 7.6e-01 ACO2 DESI1 EP300 GPX1 PLEKHM1 RBM6 RP4-756G23.5
Loneliness, isolation 1.15 1 0 0.0 0.00 1.0e+00 POR
Ever had bowel cancer screening 1.19 1 0 0.0 0.00 1.0e+00 SIK2
Diabetes diagnosed by doctor 1.32 7 4 12.1 0.65 6.0e-02 AC010883.5 EIF2S2P3 FAM212A HHEX KIF11 RBM6 RP11-138A9.1
Qualifications: nursing, teaching 1.12 5 2 6.1 0.90 1.4e-02 ABCB9 ACTR1B RBM6 RP11-282O18.3 TMEM127
Mouth/teeth dental problems: Mouth ulcers 1.48 6 4 12.1 0.56 2.5e-01 CXCR6 IRF5 KIAA1875 PLEKHM1 PPP5C SMC4
Medication for cholesterol 1.10 2 2 6.1 0.00 1.0e+00 RP11-138A9.1 SH2B3
Asthma (self-reported) 4.07 57 46 139.4 -0.89 4.6e-26 AC034102.1 AC093642.3 AC114730.11 AC114730.7 ACO2 ACSL6 AHI1 B4GALT3 BACH2 CD247 CLEC16A D2HGDH DESI1 DEXI EIF2S2P3 ERMP1 FADS1 GLDC HHEX IL18R1 IL1R1 IL1RL2 IL33 IL4R KIAA1109 KIAA1432 KIF11 KIF3A LRP1 LRRC32 MED24 NDFIP1 NHP2L1 NRROS P4HA2-AS1 PDLIM4 POLI POLR3H PPP1R1B PRKRIR RAD50 RP11-396B14.2 RP11-876N24.4 RP11-876N24.5 RP5-1115A15.1 SIK2 SLC22A5 SLC25A46 SMAD3 SPPL3 THRA TSLP UBAC2 WBP2 WDR36 ZNF652 ZNF76
Medication: Aspirin 1.14 1 0 0.0 0.00 1.0e+00 SIK2
Smoking status: Current 1.13 1 0 0.0 0.00 1.0e+00 DESI1
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.14 5 5 15.2 0.35 5.6e-01 PLEKHM1 PPP1R1B RIN3 RP11-296I10.3 ZNF76
Whole body water mass 1.54 70 55 166.7 0.58 1.3e-08 ABCB9 AC005104.3 AC034102.1 AC074117.10 ACBD4 ACSL6 ADAM1A ARID2 BRD3 C14orf39 CD164 CDK2AP1 CDK6 CEP85 CTC-228N24.3 CUX2 DCAKD DCST2 DOC2A EFEMP2 FAM133B GATAD1 GNA12 GPN3 HIVEP3 HSD3B7 KRIT1 LIN7C LOC342346 LOC595101 LUZP1 MAX NFATC3 NFKBIA NOSTRIN P4HA2-AS1 PACSIN1 PAPD7 PARP12 PDLIM4 PHC2 PLCD3 PPP4C PPTC7 PSMC3 RBM6 RIN3 RMND1 RP11-231C14.4 RP11-282O18.3 RP11-425D10.10 RSBN1L-AS1 SEC16A SEPT2 SETD8 SH2B3 SLC22A5 SMPD2 SOX15 SRPK1 TEAD3 TRIM8 UBE2Z UPF3A VPS29 WAC-AS1 ZBTB24 ZNF414 ZNF76 ZRANB1
Leg predicted mass (right) 1.48 63 48 145.5 0.51 3.9e-06 ABCB9 AC005104.3 AC006547.14 AC034102.1 AC074117.10 ACBD4 ARID2 C14orf39 C16orf93 CD164 CDC42SE2 CDK2AP1 CDK6 CEP85 CPEB4 CRTAP CTC-228N24.3 DCAKD DCST2 DOC2A EFCAB13 EFEMP2 FAM133B GATAD1 GNA12 GPN3 HIVEP3 HSD3B7 KRIT1 LIN7C LOC595101 MRPS31 NFKBIA NOSTRIN P4HA2-AS1 PACSIN1 PARP12 PDLIM4 PHC2 PLCD3 PPP4C PPTC7 RBM6 RIN3 RMND1 RP11-231C14.4 RP11-282O18.3 RP11-425D10.10 RP11-617D20.1 RPN1 RSBN1L-AS1 SEPT2 SETD8 SH2B3 SLC22A5 SMPD2 SRPK1 TEAD3 TRIM8 UPF3A VPS29 ZBTB24 ZRANB1
Arm fat mass (left) 1.22 39 24 72.7 0.06 7.4e-01 AC034102.1 ACO2 C16orf93 C17orf58 CDK6 CENPO DLG4 DOC2A FAM212A GPN3 HSD3B7 LIN7C LOC595101 LRRC25 MAP2K2 MAP2K5 PACS1 PACSIN1 PDPR PHC2 POM121C PPP4C PPTC7 RBM6 RP11-231C14.4 RP11-296I10.3 RP11-981P6.1 RP5-1115A15.1 RSBN1L-AS1 SH3GL1P3 SMAD3 TEAD3 TNFRSF14 TRIM8 UBR2 VPS29 WBP2 WWP2 ZNHIT3
Number of self-reported non-cancer illnesses 1.63 6 2 6.1 -0.98 9.0e-04 DEXI IL1RL2 LRRC32 RP11-396B14.2 SH2B3 SLC22A5
Average weekly champagne plus white wine intake 1.03 1 0 0.0 0.00 1.0e+00 FADS1
Miserableness 1.08 4 3 9.1 0.53 4.7e-01 GPX1 PLEKHM1 RBM6 RP5-1115A15.1
Guilty feelings 1.19 2 1 3.0 0.00 1.0e+00 PLEKHM1 TCEA3
Tinnitus: Yes, now most or all of the time 1.01 1 0 0.0 0.00 1.0e+00 PNPO
Medication: Blood pressure 1.19 8 4 12.1 -0.76 2.9e-02 MYNN P4HA2-AS1 PDLIM4 PLEKHM1 RP11-138A9.1 SH2B3 SIK2 SLC22A5
Pain type(s) experienced in last month: Hip pain 1.08 1 0 0.0 0.00 1.0e+00 NOV
High cholesterol (Self-reported) 1.57 10 7 21.2 -0.03 9.3e-01 CARM1 LPL PNPO PVRL2 SIDT2 TOMM40 TSEN2 WBP2 ZDHHC18 ZNF259
Medication: Bendroflumethiazide 1.21 4 1 3.0 -0.68 3.2e-01 HSD3B7 P4HA2-AS1 PDLIM4 ZDHHC18
Medication: Paracetamol 1.05 4 2 6.1 0.67 3.3e-01 DCAKD GPX1 LRP1 PLEKHM1
Medication: Atorvastatin 1.22 2 2 6.1 0.00 1.0e+00 TOMM40 ZNF259
Illnesses of father: High blood pressure 1.20 1 0 0.0 0.00 1.0e+00 UPF3A
Ever smoked 1.05 2 1 3.0 0.00 1.0e+00 PHC2 RAD54L2
Basal metabolic rate 1.49 67 51 154.5 0.53 3.2e-07 ABCB9 AC005104.3 AC006547.14 AC034102.1 AC074117.10 ACBD4 ARID2 C14orf39 C16orf93 CD164 CDK2AP1 CDK6 CEP85 CTC-228N24.3 CUX2 DCAKD DCST2 DESI1 DOC2A EFEMP2 FAM133B GATAD1 GNA12 GPN3 HIVEP3 HSD3B7 KRIT1 LIN7C LOC342346 LOC595101 MAX NFATC3 NFKBIA NOSTRIN P4HA2-AS1 PACSIN1 PAPD7 PARP12 PDLIM4 PHC2 PLCD3 PPP4C PPTC7 PSMC3 RBM6 RIN3 RMND1 RP11-231C14.4 RP11-282O18.3 RP11-425D10.10 RSBN1L-AS1 SEC16A SEPT2 SETD8 SH2B3 SH3GL1P3 SLC22A5 SMPD2 SRPK1 TEAD3 TRIM8 UPF3A VPS29 ZBTB24 ZNF414 ZNF76 ZRANB1
Leg fat percentage (left) 1.36 44 27 81.8 -0.34 2.3e-02 ATP9A C16orf93 C17orf58 CENPO CTC-228N24.3 CXCL17 DARS DCAKD DOC2A FAM212A GPN3 GPX1 HSD3B7 JUND LIN7C LOC595101 LOC729082 LRP1 LRRC25 MAP2K2 MAP2K5 MAPK13 NDUFAF1 NUSAP1 OIP5-AS1 PACS1 PDPR POM121C PPARG PPP4C PPTC7 PSMC3 RBM6 RIN3 RP11-231C14.4 RP11-296I10.3 RP11-867G23.2 RP11-981P6.1 RP5-1115A15.1 SH3GL1P3 SMAD3 TEAD3 TFPI WWP2
Arm fat-free mass (left) 1.52 64 53 160.6 0.55 1.9e-07 ABCB9 AC005104.3 AC034102.1 AC074117.10 ACBD4 ADAM1A AKAP13 ARID2 C14orf39 CD164 CDK2AP1 CDK6 CUX2 DCAKD DOC2A EFEMP2 FAM133B GATAD1 GNA12 GPN3 GPX1 HIVEP3 HSD3B7 KRIT1 LIN7C LOC342346 LOC595101 MAX NFATC3 NFKBIA NOSTRIN P4HA2-AS1 PACSIN1 PAPD7 PARP12 PDLIM4 PHC2 PLCD3 PPP4C PPTC7 PSMB7 RAPGEF1 RBM6 RIN3 RP11-231C14.4 RP11-282O18.3 RP11-425D10.10 RSBN1L-AS1 SEC16A SEPT2 SETD8 SH2B3 SH3GL1P3 SLC22A5 SMPD2 SOX15 TEAD3 TRIM8 UPF3A VPS29 ZBTB24 ZNF414 ZNF76 ZRANB1
Number of operations (self-reported) 1.13 2 0 0.0 0.00 1.0e+00 MYNN PSMB7
Average weekly beer plus cider intake 1.10 2 1 3.0 0.00 1.0e+00 POR RBM6
Irritability 1.14 5 1 3.0 0.75 1.5e-01 AC010883.5 ACO2 ARIH2 FADS1 PLEKHM1
Fractured/broken bones in last 5 years 1.14 1 0 0.0 0.00 1.0e+00 C17orf58
Diastolic blood pressure, automated reading 1.50 37 25 75.8 -0.69 1.7e-06 ABCB9 AC002310.12 AC010883.5 ADAM1A ADRA2B ANKRD36 C16orf93 CD164 CDK2AP1 CLIC4 CPEB4 CSTA DARS DCAKD DLG4 FAHD2CP GPN3 HSD3B7 ITPRIPL1 LINC00342 LOC729082 MAPKAPK5-AS1 MED19 NDUFAF1 NUSAP1 OIP5-AS1 P4HA2-AS1 PPTC7 RBM6 RP11-282O18.3 RP5-1115A15.1 SETD8 SH2B3 SPTBN5 TMEM116 TMEM127 VPS29
Myopia 1.02 1 0 0.0 0.00 1.0e+00 LRP1
Vascular/heart problems diagnosed by doctor 1.33 20 11 33.3 0.74 1.8e-04 AC006547.14 ADRB2 DLG4 HSD3B7 MAPKAPK5-AS1 OIP5-AS1 P4HA2-AS1 PDLIM4 PSMC3 RP5-1115A15.1 RRP1B SH2B3 SIK2 SLC22A5 TMEM116 TP53INP1 TRMT61A TSPY26P UBE2Z ZNF652
Cholesterol lowering medication 1.34 6 4 12.1 -0.01 9.9e-01 CARM1 LPL PVRL2 RP11-138A9.1 TOMM40 ZNF259
Pain experienced in last month 1.14 2 1 3.0 0.00 1.0e+00 AC034102.1 LRP1
Basal cell carcinoma (self-reported) 1.23 1 0 0.0 0.00 1.0e+00 EP300
Deep venous thrombosis (DVT) (self-reported) 1.08 2 2 6.1 0.00 1.0e+00 CACFD1 GBGT1
Impedance of whole body 1.29 65 51 154.5 -0.38 1.4e-03 AC005104.3 AC006547.14 AC010883.5 AC034102.1 AC074117.10 AC103965.1 ACBD4 ACO2 ARID2 ARIH2 ARNT CRHR1-IT1 CSDC2 CTC-228N24.3 DCAKD DCST2 DESI1 DOC2A EFEMP2 EP300 ERMP1 GPX1 GS1-393G12.12 HEMK1 HSD3B7 ITIH4-AS1 JUND LIN7C LOC342346 LOC595101 LPAR2 LRRC25 MARK1 MCL1 MUS81 NFATC3 NHP2L1 PACSIN1 PHC2 PLA2G15 PLEKHM1 POLR3H POM121C PPP4C PSMB7 RBM6 RIN3 RMI1 RNF185 RNF215 RP11-231C14.4 RP11-393I2.4 RP11-425D10.10 RP11-502I4.3 RP13-131K19.6 RP4-756G23.5 SCNM1 SEMA3B-AS1 TEAD3 TNIP2 TRIM8 TSPAN3 UPF3A VPS29 ZNF652
Leg fat mass (left) 1.25 42 32 97.0 0.20 2.0e-01 AC034102.1 C16orf93 C17orf58 CD164 CDK6 CENPO CTC-228N24.3 DARS DOC2A EFEMP2 FAM212A GPN3 GPX1 HSD3B7 JUND LIN7C LOC595101 LRRC25 MAP2K2 MAP2K5 PACS1 PACSIN1 PAPD7 PDPR PHC2 POM121C PPP4C PPTC7 RBM6 RP11-231C14.4 RP11-867G23.2 RP11-981P6.1 RP5-1115A15.1 RSBN1L-AS1 SH3GL1P3 SMAD3 TEAD3 TFPI TNFRSF14 TRIM8 VPS29 WWP2
Arm predicted mass (left) 1.51 63 46 139.4 0.55 2.0e-07 ABCB9 AC005104.3 AC034102.1 AC074117.10 ACBD4 ADAM1A ALDH2 ARID2 C14orf39 CD164 CDK2AP1 CDK6 CUX2 DCAKD DOC2A EFEMP2 FAM133B GATAD1 GNA12 GPN3 GPX1 HSD3B7 KRIT1 LIN7C LOC342346 LOC595101 MAX NFATC3 NFKBIA NOSTRIN P4HA2-AS1 PACSIN1 PAPD7 PARP12 PDLIM4 PHC2 PLCD3 PPP4C PPTC7 PSMB7 RBM6 RIN3 RP11-231C14.4 RP11-282O18.3 RP11-425D10.10 RSBN1L-AS1 SEC16A SEPT2 SETD8 SH2B3 SH3GL1P3 SLC22A5 SMPD2 SOX15 SRPK1 TEAD3 TRIM8 UPF3A VPS29 ZBTB24 ZNF414 ZNF76 ZRANB1

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 166 4.75 7.76
GTEx Adipose Visceral Omentum 125 6.14 9.12
GTEx Adrenal Gland 82 5.63 9.17
GTEx Artery Aorta 148 4.97 8.00
GTEx Artery Coronary 63 5.32 7.66
GTEx Artery Tibial 176 4.68 8.15
GTEx Brain Caudate basal ganglia 41 4.46 7.30
GTEx Brain Cerebellar Hemisphere 77 5.17 8.44
GTEx Brain Cerebellum 109 5.50 7.83
GTEx Brain Cortex 60 5.80 8.93
GTEx Brain Frontal Cortex BA9 56 6.05 10.26
GTEx Brain Hippocampus 33 6.29 9.58
GTEx Brain Hypothalamus 33 5.58 8.70
GTEx Brain Nucleus accumbens basal ganglia 44 5.08 9.30
GTEx Brain Putamen basal ganglia 37 5.93 9.37
GTEx Breast Mammary Tissue 99 5.01 8.96
GTEx Breast Mammary Tissue (Male) 53 4.44 7.71
GTEx Breast Mammary Tissue (Female) 84 5.11 8.31
GTEx Cells EBV-transformed lymphocytes 72 5.07 7.62
GTEx Cells Transformed fibroblasts 217 5.17 7.44
GTEx Colon Sigmoid 78 5.33 8.94
GTEx Colon Transverse 116 5.62 9.53
GTEx Esophagus Gastroesophageal Junction 73 5.05 8.32
GTEx Esophagus Mucosa 188 5.66 8.07
GTEx Esophagus Muscularis 163 5.04 7.87
GTEx Heart Atrial Appendage 81 5.13 8.35
GTEx Heart Left Ventricle 80 5.23 9.92
GTEx Liver 43 6.00 10.58
GTEx Lung 156 5.43 8.39
GTEx Muscle Skeletal 146 5.05 7.78
GTEx Nerve Tibial 218 5.04 8.02
GTEx Ovary 52 5.72 7.73
GTEx Pancreas 90 5.51 9.69
GTEx Pituitary 70 6.27 8.90
GTEx Prostate 49 5.88 9.50
GTEx Skin Not Sun Exposed Suprapubic 135 5.49 9.05
GTEx Skin Sun Exposed Lower leg 193 5.31 7.94
GTEx Small Intestine Terminal Ileum 25 5.41 9.16
GTEx Spleen 92 6.52 9.08
GTEx Stomach 90 6.19 9.63
GTEx Testis 165 5.23 8.73
GTEx Thyroid 235 5.88 8.81
GTEx Uterus 33 5.82 7.31
GTEx Vagina 34 5.35 9.01
GTEx Whole Blood 144 7.24 10.13
METSIM Adipose 217 4.71 6.85
NTR Blood 148 6.16 8.29
ROSMAP Brain Pre-frontal Cortex 221 5.03 7.16
YFS Blood 239 5.18 7.99
CommonMind Brain Pre-frontal Cortex 216 4.02 6.09
TCGA Breast Tumor 39 5.09 7.83
TCGA Breast Normal 163 3.87 6.57
TCGA Ovarian Tumor 90 3.08 5.10
TCGA Prostate Tumor 157 4.54 6.51